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Found 351 Enz. Inhib. hit(s) with Target = 'Chitinase'
TargetChitinase(Ostrinia furnacalis)
Dalian University Of Technology

Curated by ChEMBL
LigandPNGBDBM50514507(CHEMBL1583158)
Affinity DataKd:  85nMAssay Description:Binding affinity to Ostrinia furnacalis chitinase h catalytic domain overexpressed in Pichia pastoris by isothermal titration calorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChitinase-3-like protein 1(Human)
Molecure

US Patent
LigandPNGBDBM616496(US20230278996, Example 5.)
Affinity DataKd: <100nMAssay Description:The standard experimental protocol for YKL-40 indirect binding AlphaScreen assay comprised of 5 step additions to wells of a 96 well plate: (i) in th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetChitinase B(Serratia marcescens)
Dalian University Of Technology

Curated by ChEMBL
LigandPNGBDBM50514507(CHEMBL1583158)
Affinity DataKd:  190nMAssay Description:Binding affinity to Serratia marcescens chitinase b catalytic domain overexpressed in Escherichia coli BL21(DE3) cells by isothermal titration calori...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChitinase B(Serratia marcescens)
Dalian University Of Technology

Curated by ChEMBL
LigandPNGBDBM50173286(5-[3-[amino-(methylcarbamoylamino)methylidene]amin...)
Affinity DataKd:  3.30E+4nMAssay Description:Inhibition of Serratia marcescens chitinase BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChitinase(Ostrinia furnacalis)
Dalian University Of Technology

Curated by ChEMBL
LigandPNGBDBM50514507(CHEMBL1583158)
Affinity DataKi:  9nMAssay Description:Inhibition of Ostrinia furnacalis chitinase h catalytic domain overexpressed in Pichia pastoris using 4MU-(GlcNAc)2 as substrate after 30 mins by flu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChitinase B(Serratia marcescens)
Dalian University Of Technology

Curated by ChEMBL
LigandPNGBDBM10854(4-[(1S,4R,10S,13S,16S,18R)-10-{3-[(acetamidomethan...)
Affinity DataKi:  20nM ΔG°:  -45.7kJ/molepH: 5.5 T: 2°CAssay Description:The IC50s of inhibitor against the human chitinase were determined using the fluorogenic substrate 4MU-NAG3. The fluorescence of the liberated 4MU wa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChitinase B(Serratia marcescens)
Dalian University Of Technology

Curated by ChEMBL
LigandPNGBDBM50514507(CHEMBL1583158)
Affinity DataKi:  58nMAssay Description:Inhibition of Serratia marcescens chitinase b catalytic domain overexpressed in Escherichia coli BL21(DE3) cells using 4MU-(GlcNAc)2 as substrate aft...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChitinase(Onchocerca volvulus)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50022832(Rafoxanide)
Affinity DataKi:  130nMAssay Description:Competitive inhibition of Onchocerca volvulus L3 larvae chitinase using 20 uM 4-methylumbelliferyl-N,N',N''-beta-chitotrioside as substrate after 10 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChitinase B(Serratia marcescens)
Dalian University Of Technology

Curated by ChEMBL
LigandPNGBDBM50587858(9-O-(Benzoyl)Berberrubine Chloride | CHEMBL1223325)
Affinity DataKi:  150nMAssay Description:Inhibition of Serratia marcescens chitinase B expressed in Escherichia coli BL21(DE3) cells using MU-(GlcNAc)2 as a substrate assessed as inhibition ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetChitinase B(Serratia marcescens)
Dalian University Of Technology

Curated by ChEMBL
LigandPNGBDBM50587859(CHEMBL5180998)
Affinity DataKi:  150nMAssay Description:Inhibition of Serratia marcescens chitinase B expressed in Escherichia coli BL21(DE3) cells using MU-(GlcNAc)2 as a substrate assessed as inhibition ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetChitinase B(Serratia marcescens)
Dalian University Of Technology

Curated by ChEMBL
LigandPNGBDBM50587857(CHEMBL5199149)
Affinity DataKi:  150nMAssay Description:Inhibition of Serratia marcescens chitinase B expressed in Escherichia coli BL21(DE3) cells using MU-(GlcNAc)2 as a substrate assessed as inhibition ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetChitinase(Hypocrea rufa)
University Of Siena

Curated by ChEMBL
LigandPNGBDBM50254171(CHEMBL4069120)
Affinity DataKi:  220nMAssay Description:Inhibition of Trichoderma viride chitinase incubated for 10 mins to 3 hrs using 4-nitrophenyl N-acetyl-beta-D-glucosaminide substrate by spectrophoto...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChitinase(Ostrinia furnacalis)
Dalian University Of Technology

Curated by ChEMBL
LigandPNGBDBM50514508(CHEMBL4549449)
Affinity DataKi:  390nMAssay Description:Inhibition of Ostrinia furnacalis chitinase h catalytic domain overexpressed in Pichia pastoris using 4MU-(GlcNAc)2 as substrate after 30 mins by flu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChitinase B(Serratia marcescens)
Dalian University Of Technology

Curated by ChEMBL
LigandPNGBDBM50514508(CHEMBL4549449)
Affinity DataKi:  410nMAssay Description:Inhibition of Serratia marcescens chitinase b catalytic domain overexpressed in Escherichia coli BL21(DE3) cells using 4MU-(GlcNAc)2 as substrate aft...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChitinase(Onchocerca volvulus)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50063753(CHEMBL12131 | Closantel | N-(5-chloro-4-((4-chloro...)
Affinity DataKi:  468nMAssay Description:Inhibition of Onchocerca volvulus L3 larvae chitinase using 4-methylumbelliferyl-N,N',N''-beta-chitotrioside as a profluorescent substrate after 10 m...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChitinase(Onchocerca volvulus)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50063753(CHEMBL12131 | Closantel | N-(5-chloro-4-((4-chloro...)
Affinity DataKi:  470nMAssay Description:Competitive inhibition of Onchocerca volvulus L3 larvae chitinase using 20 uM 4-methylumbelliferyl-N,N',N''-beta-chitotrioside as substrate after 10 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChitinase(Onchocerca volvulus)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50498224(CHEMBL3577757)
Affinity DataKi:  980nMAssay Description:Competitive inhibition of L3 larval stage of Onchocerca volvulus chitinase using 4-methylumbelliferyl-N-N'-N''-beta-chitotrioside as substrate assess...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetChitinase(Onchocerca volvulus)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM100152(7-methoxy-1-methyl-9H-beta-carboline;hydrochloride...)
Affinity DataKi:  3.78E+3nMAssay Description:Competitive inhibition of L3 larval stage of Onchocerca volvulus chitinase using 4-methylumbelliferyl-N-N'-N''-beta-chitotrioside as substrate assess...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChitinase(Hypocrea rufa)
University Of Siena

Curated by ChEMBL
LigandPNGBDBM50254176(CHEMBL3040884)
Affinity DataKi:  1.41E+4nMAssay Description:Inhibition of Trichoderma viride chitinase incubated for 10 mins to 3 hrs using 4-nitrophenyl N-acetyl-beta-D-glucosaminide substrate by spectrophoto...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChitinase(Hypocrea rufa)
University Of Siena

Curated by ChEMBL
LigandPNGBDBM50254177(CHEMBL3040820)
Affinity DataKi:  1.78E+4nMAssay Description:Inhibition of Trichoderma viride chitinase incubated for 10 mins to 3 hrs using 4-nitrophenyl N-acetyl-beta-D-glucosaminide substrate by spectrophoto...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChitinase(Hypocrea rufa)
University Of Siena

Curated by ChEMBL
LigandPNGBDBM50254178(CHEMBL3558827)
Affinity DataKi:  3.13E+4nMAssay Description:Inhibition of Trichoderma viride chitinase incubated for 10 mins to 3 hrs using 4-nitrophenyl N-acetyl-beta-D-glucosaminide substrate by spectrophoto...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChitinase B(Serratia marcescens)
Dalian University Of Technology

Curated by ChEMBL
LigandPNGBDBM10853((2R,5S,8S,11S,15S)-8-benzyl-2,7-dimethyl-5-[3-({[(...)
Affinity DataKi:  3.30E+4nM ΔG°:  -26.6kJ/molepH: 5.5 T: 2°CAssay Description:The IC50s of inhibitor against the human chitinase were determined using the fluorogenic substrate 4MU-NAG3. The fluorescence of the liberated 4MU wa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChitinase(Hypocrea rufa)
University Of Siena

Curated by ChEMBL
LigandPNGBDBM50254180(CHEMBL3558806)
Affinity DataKi:  3.48E+4nMAssay Description:Inhibition of Trichoderma viride chitinase incubated for 10 mins to 3 hrs using 4-nitrophenyl N-acetyl-beta-D-glucosaminide substrate by spectrophoto...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChitinase(Hypocrea rufa)
University Of Siena

Curated by ChEMBL
LigandPNGBDBM50254181(CHEMBL3558803)
Affinity DataKi:  3.58E+4nMAssay Description:Inhibition of Trichoderma viride chitinase incubated for 10 mins to 3 hrs using 4-nitrophenyl N-acetyl-beta-D-glucosaminide substrate by spectrophoto...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChitinase(Hypocrea rufa)
University Of Siena

Curated by ChEMBL
LigandPNGBDBM50254182(CHEMBL3040830)
Affinity DataKi:  4.20E+4nMAssay Description:Inhibition of Trichoderma viride chitinase incubated for 10 mins to 3 hrs using 4-nitrophenyl N-acetyl-beta-D-glucosaminide substrate by spectrophoto...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChitinase(Hypocrea rufa)
University Of Siena

Curated by ChEMBL
LigandPNGBDBM50254179(CHEMBL3558802)
Affinity DataKi:  4.53E+4nMAssay Description:Inhibition of Trichoderma viride chitinase incubated for 10 mins to 3 hrs using 4-nitrophenyl N-acetyl-beta-D-glucosaminide substrate by spectrophoto...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChitinase(Hypocrea rufa)
University Of Siena

Curated by ChEMBL
LigandPNGBDBM50254183(CHEMBL575667)
Affinity DataKi:  5.08E+4nMAssay Description:Inhibition of Trichoderma viride chitinase incubated for 10 mins to 3 hrs using 4-nitrophenyl N-acetyl-beta-D-glucosaminide substrate by spectrophoto...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChitinase(Onchocerca volvulus)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50022822(CHEMBL483713)
Affinity DataIC50:  1.98E+3nMAssay Description:Inhibition of Onchocerca volvulus L3 larvae chitinase using 20 uM 4-methylumbelliferyl-N,N',N''-beta-chitotrioside as substrate after 10 mins by micr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChitinase(Onchocerca volvulus)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50022823(CHEMBL3297930)
Affinity DataIC50:  1.28E+3nMAssay Description:Inhibition of Onchocerca volvulus L3 larvae chitinase using 20 uM 4-methylumbelliferyl-N,N',N''-beta-chitotrioside as substrate after 10 mins by micr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChitinase(Onchocerca volvulus)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50022824(CHEMBL3298097)
Affinity DataIC50:  1.81E+3nMAssay Description:Inhibition of Onchocerca volvulus L3 larvae chitinase using 20 uM 4-methylumbelliferyl-N,N',N''-beta-chitotrioside as substrate after 10 mins by micr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChitinase(Onchocerca volvulus)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50022825(CHEMBL3298098)
Affinity DataIC50:  3.71E+3nMAssay Description:Inhibition of Onchocerca volvulus L3 larvae chitinase using 20 uM 4-methylumbelliferyl-N,N',N''-beta-chitotrioside as substrate after 10 mins by micr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChitinase(Onchocerca volvulus)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50022826(CHEMBL3298099)
Affinity DataIC50:  1.06E+3nMAssay Description:Inhibition of Onchocerca volvulus L3 larvae chitinase using 20 uM 4-methylumbelliferyl-N,N',N''-beta-chitotrioside as substrate after 10 mins by micr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChitinase(Onchocerca volvulus)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50022827(CHEMBL3298100)
Affinity DataIC50:  1.11E+3nMAssay Description:Inhibition of Onchocerca volvulus L3 larvae chitinase using 20 uM 4-methylumbelliferyl-N,N',N''-beta-chitotrioside as substrate after 10 mins by micr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChitinase(Onchocerca volvulus)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50022828(CHEMBL3298101)
Affinity DataIC50:  1.57E+3nMAssay Description:Inhibition of Onchocerca volvulus L3 larvae chitinase using 20 uM 4-methylumbelliferyl-N,N',N''-beta-chitotrioside as substrate after 10 mins by micr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChitinase(Onchocerca volvulus)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50022829(CHEMBL3298102)
Affinity DataIC50:  700nMAssay Description:Inhibition of Onchocerca volvulus L3 larvae chitinase using 20 uM 4-methylumbelliferyl-N,N',N''-beta-chitotrioside as substrate after 10 mins by micr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChitinase(Onchocerca volvulus)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50022830(CHEMBL3298103)
Affinity DataIC50:  600nMAssay Description:Inhibition of Onchocerca volvulus L3 larvae chitinase using 20 uM 4-methylumbelliferyl-N,N',N''-beta-chitotrioside as substrate after 10 mins by micr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChitinase(Onchocerca volvulus)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50063753(CHEMBL12131 | Closantel | N-(5-chloro-4-((4-chloro...)
Affinity DataIC50:  1.60E+3nMAssay Description:Inhibition of Onchocerca volvulus L3 larvae chitinase using 20 uM 4-methylumbelliferyl-N,N',N''-beta-chitotrioside as substrate after 10 mins by micr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChitinase(Onchocerca volvulus)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50022832(Rafoxanide)
Affinity DataIC50:  340nMAssay Description:Inhibition of Onchocerca volvulus L3 larvae chitinase using 20 uM 4-methylumbelliferyl-N,N',N''-beta-chitotrioside as substrate after 10 mins by micr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChitinase(Onchocerca volvulus)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50022834(CHEMBL3298104)
Affinity DataIC50:  870nMAssay Description:Inhibition of Onchocerca volvulus L3 larvae chitinase using 20 uM 4-methylumbelliferyl-N,N',N''-beta-chitotrioside as substrate after 10 mins by micr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChitinase(Onchocerca volvulus)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50022842(CHEMBL3298105)
Affinity DataIC50:  1.74E+3nMAssay Description:Inhibition of Onchocerca volvulus L3 larvae chitinase using 20 uM 4-methylumbelliferyl-N,N',N''-beta-chitotrioside as substrate after 10 mins by micr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChitinase(Onchocerca volvulus)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50022885(CHEMBL3298106)
Affinity DataIC50:  1.20E+3nMAssay Description:Inhibition of Onchocerca volvulus L3 larvae chitinase using 20 uM 4-methylumbelliferyl-N,N',N''-beta-chitotrioside as substrate after 10 mins by micr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChitinase(Onchocerca volvulus)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50022886(CHEMBL3298107)
Affinity DataIC50:  940nMAssay Description:Inhibition of Onchocerca volvulus L3 larvae chitinase using 20 uM 4-methylumbelliferyl-N,N',N''-beta-chitotrioside as substrate after 10 mins by micr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChitinase(Onchocerca volvulus)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50022887(CHEMBL3298108)
Affinity DataIC50:  890nMAssay Description:Inhibition of Onchocerca volvulus L3 larvae chitinase using 20 uM 4-methylumbelliferyl-N,N',N''-beta-chitotrioside as substrate after 10 mins by micr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChitinase(Onchocerca volvulus)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50022888(CHEMBL3298109)
Affinity DataIC50:  1.29E+3nMAssay Description:Inhibition of Onchocerca volvulus L3 larvae chitinase using 20 uM 4-methylumbelliferyl-N,N',N''-beta-chitotrioside as substrate after 10 mins by micr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChitinase(Onchocerca volvulus)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50022890(CHEMBL3298110)
Affinity DataIC50:  470nMAssay Description:Inhibition of Onchocerca volvulus L3 larvae chitinase using 20 uM 4-methylumbelliferyl-N,N',N''-beta-chitotrioside as substrate after 10 mins by micr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChitinase(Onchocerca volvulus)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50022891(CHEMBL3298111)
Affinity DataIC50:  990nMAssay Description:Inhibition of Onchocerca volvulus L3 larvae chitinase using 20 uM 4-methylumbelliferyl-N,N',N''-beta-chitotrioside as substrate after 10 mins by micr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChitinase(Onchocerca volvulus)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50022892(CHEMBL3298112)
Affinity DataIC50:  370nMAssay Description:Inhibition of Onchocerca volvulus L3 larvae chitinase using 20 uM 4-methylumbelliferyl-N,N',N''-beta-chitotrioside as substrate after 10 mins by micr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChitinase B(Serratia marcescens)
Dalian University Of Technology

Curated by ChEMBL
LigandPNGBDBM50344942(CHEMBL532 | E-MYCIN E | ERYTHROMYCIN | ERYTHROMYCI...)
Affinity DataIC50: >3.00E+5nMAssay Description:Inhibition of Serratia marcescens chitinase ChiB assessed as reduction in chitinolytic activity using 4MU-(GlcNAc)2 substrate by fluorescence based a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChitinase B(Serratia marcescens)
Dalian University Of Technology

Curated by ChEMBL
LigandPNGBDBM50089844(CHEMBL3577623)
Affinity DataIC50:  1.40E+3nMAssay Description:Inhibition of Serratia marcescens chitinase ChiB assessed as reduction in chitinolytic activity using 4MU-(GlcNAc)2 substrate by fluorescence based a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChitinase B(Serratia marcescens)
Dalian University Of Technology

Curated by ChEMBL
LigandPNGBDBM50089845(CHEMBL3577622)
Affinity DataIC50:  1.70E+3nMAssay Description:Inhibition of Serratia marcescens chitinase ChiB assessed as reduction in chitinolytic activity using 4MU-(GlcNAc)2 substrate by fluorescence based a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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