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Found 644 Enz. Inhib. hit(s) with Target = 'Heme oxygenase'
TargetHeme oxygenase HutZ [D132E](Vibrio cholerae)
Hokkaido University

LigandPNGBDBM231681(Hemin)
Affinity DataKd:  27nMpH: 8.0Assay Description:Heme binding was tracked by difference spectroscopy in the Soret region of the UV−visible spectrum. Successive aliquots of 0.5 mM hemin in 0.1 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeme oxygenase HutZ [D132N](Vibrio cholerae)
Hokkaido University

LigandPNGBDBM231681(Hemin)
Affinity DataKd:  150nMpH: 8.0Assay Description:Heme binding was tracked by difference spectroscopy in the Soret region of the UV−visible spectrum. Successive aliquots of 0.5 mM hemin in 0.1 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeme oxygenase HutZ [D132L](Vibrio cholerae)
Hokkaido University

LigandPNGBDBM231681(Hemin)
Affinity DataKd:  470nMpH: 8.0Assay Description:Heme binding was tracked by difference spectroscopy in the Soret region of the UV−visible spectrum. Successive aliquots of 0.5 mM hemin in 0.1 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeme oxygenase HutZ [D132N](Vibrio cholerae)
Hokkaido University

LigandPNGBDBM231681(Hemin)
Affinity DataKd:  1.90E+3nMpH: 6.0Assay Description:Heme binding was tracked by difference spectroscopy in the Soret region of the UV−visible spectrum. Successive aliquots of 0.5 mM hemin in 0.1 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeme oxygenase HutZ [D132E](Vibrio cholerae)
Hokkaido University

LigandPNGBDBM231681(Hemin)
Affinity DataKd:  4.10E+3nMpH: 6.0Assay Description:Heme binding was tracked by difference spectroscopy in the Soret region of the UV−visible spectrum. Successive aliquots of 0.5 mM hemin in 0.1 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeme oxygenase 2(Rattus norvegicus (rat))
University Of Catania

Curated by ChEMBL
LigandPNGBDBM50271513(1-(4-(4-bromophenoxy)butyl)-1H-imidazole | CHEMBL4...)
Affinity DataIC50:  7.50E+4nMAssay Description:Inhibition of Sprague-Dawley rat brain HO-2 assessed as bilirubin formation after 60 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeme oxygenase 2(Rattus norvegicus (rat))
University Of Catania

Curated by ChEMBL
LigandPNGBDBM50271548(1-(4-(2-bromophenoxy)butyl)-1H-imidazole | CHEMBL5...)
Affinity DataIC50:  2.40E+4nMAssay Description:Inhibition of Sprague-Dawley rat brain HO-2 assessed as bilirubin formation after 60 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeme oxygenase 2(Rattus norvegicus (rat))
University Of Catania

Curated by ChEMBL
LigandPNGBDBM50438650(CHEMBL2414455)
Affinity DataIC50:  7.00E+4nMAssay Description:Inhibition of Sprague-Dawley rat brain HO-2 assessed as bilirubin formation after 60 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeme oxygenase 2(Rattus norvegicus (rat))
University Of Catania

Curated by ChEMBL
LigandPNGBDBM50438651(CHEMBL2414454)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of Sprague-Dawley rat brain HO-2 assessed as bilirubin formation after 60 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeme oxygenase 2(Rattus norvegicus (rat))
University Of Catania

Curated by ChEMBL
LigandPNGBDBM50438652(CHEMBL2414453)
Affinity DataIC50:  9.00E+4nMAssay Description:Inhibition of Sprague-Dawley rat brain HO-2 assessed as bilirubin formation after 60 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeme oxygenase 2(Rattus norvegicus (rat))
University Of Catania

Curated by ChEMBL
LigandPNGBDBM50438653(CHEMBL2414450)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of Sprague-Dawley rat brain HO-2 assessed as bilirubin formation after 60 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeme oxygenase 2(Rattus norvegicus (rat))
University Of Catania

Curated by ChEMBL
LigandPNGBDBM50438654(CHEMBL2414448)
Affinity DataIC50:  2.10E+4nMAssay Description:Inhibition of Sprague-Dawley rat brain HO-2 assessed as bilirubin formation after 60 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeme oxygenase 2(Rattus norvegicus (rat))
University Of Catania

Curated by ChEMBL
LigandPNGBDBM50438655(CHEMBL2414446)
Affinity DataIC50:  2.70E+4nMAssay Description:Inhibition of Sprague-Dawley rat brain HO-2 assessed as bilirubin formation after 60 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeme oxygenase 2(Rattus norvegicus (rat))
University Of Catania

Curated by ChEMBL
LigandPNGBDBM50438656(CHEMBL2414445)
Affinity DataIC50:  3.00E+4nMAssay Description:Inhibition of Sprague-Dawley rat brain HO-2 assessed as bilirubin formation after 60 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeme oxygenase 2(Rattus norvegicus (rat))
University Of Catania

Curated by ChEMBL
LigandPNGBDBM50438657(CHEMBL1363752)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of Sprague-Dawley rat brain HO-2 assessed as bilirubin formation after 60 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeme oxygenase 2(Rattus norvegicus (rat))
University Of Catania

Curated by ChEMBL
LigandPNGBDBM50271549(1-(4-(3-bromophenoxy)butyl)-1H-imidazole | CHEMBL4...)
Affinity DataIC50:  2.20E+3nMAssay Description:Inhibition of Sprague-Dawley rat brain HO-2 assessed as bilirubin formation after 60 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeme oxygenase 2(Rattus norvegicus (rat))
University Of Catania

Curated by ChEMBL
LigandPNGBDBM84805(1-azolyl-4-phenyl-2-butanone, 7)
Affinity DataIC50:  3.40E+4nMAssay Description:Inhibition of Sprague-Dawley rat brain HO-2 assessed as bilirubin formation after 60 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeme oxygenase 2(Rattus norvegicus (rat))
University Of Catania

Curated by ChEMBL
LigandPNGBDBM50438658(CHEMBL1188560)
Affinity DataIC50:  1.80E+3nMAssay Description:Inhibition of Sprague-Dawley rat brain HO-2 assessed as bilirubin formation after 60 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeme oxygenase 2(Rattus norvegicus (rat))
University Of Catania

Curated by ChEMBL
LigandPNGBDBM50240895(2-(1H-Imidazol-1-yl)-1-(4-nitrophenyl)ethanone | 2...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of Sprague-Dawley rat brain HO-2 assessed as bilirubin formation after 60 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeme oxygenase 2(Rattus norvegicus (rat))
University Of Catania

Curated by ChEMBL
LigandPNGBDBM50044424(4-(((2S,4S)-2-((1H-imidazol-1-yl)methyl)-2-(4-chlo...)
Affinity DataIC50:  2.45E+4nMAssay Description:Inhibition of Sprague-Dawley rat brain HO-2 assessed as bilirubin formation after 60 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeme oxygenase 1(Rattus norvegicus (rat))
University Of Catania

Curated by ChEMBL
LigandPNGBDBM50271513(1-(4-(4-bromophenoxy)butyl)-1H-imidazole | CHEMBL4...)
Affinity DataIC50:  3.10E+4nMAssay Description:Inhibition of Sprague-Dawley rat spleen microsomal HO-1 assessed as bilirubin formation after 60 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeme oxygenase 1(Rattus norvegicus (rat))
University Of Catania

Curated by ChEMBL
LigandPNGBDBM50271548(1-(4-(2-bromophenoxy)butyl)-1H-imidazole | CHEMBL5...)
Affinity DataIC50:  5.30E+4nMAssay Description:Inhibition of Sprague-Dawley rat spleen microsomal HO-1 assessed as bilirubin formation after 60 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeme oxygenase 1(Rattus norvegicus (rat))
University Of Catania

Curated by ChEMBL
LigandPNGBDBM50438650(CHEMBL2414455)
Affinity DataIC50:  3.80E+4nMAssay Description:Inhibition of Sprague-Dawley rat spleen microsomal HO-1 assessed as bilirubin formation after 60 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeme oxygenase 1(Rattus norvegicus (rat))
University Of Catania

Curated by ChEMBL
LigandPNGBDBM50438651(CHEMBL2414454)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of Sprague-Dawley rat spleen microsomal HO-1 assessed as bilirubin formation after 60 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeme oxygenase 1(Rattus norvegicus (rat))
University Of Catania

Curated by ChEMBL
LigandPNGBDBM50438652(CHEMBL2414453)
Affinity DataIC50:  7.50E+4nMAssay Description:Inhibition of Sprague-Dawley rat spleen microsomal HO-1 assessed as bilirubin formation after 60 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeme oxygenase 1(Rattus norvegicus (rat))
University Of Catania

Curated by ChEMBL
LigandPNGBDBM50438659(CHEMBL2414452)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of Sprague-Dawley rat spleen microsomal HO-1 assessed as bilirubin formation after 60 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeme oxygenase 1(Rattus norvegicus (rat))
University Of Catania

Curated by ChEMBL
LigandPNGBDBM50438660(CHEMBL1404869)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of Sprague-Dawley rat spleen microsomal HO-1 assessed as bilirubin formation after 60 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeme oxygenase 1(Rattus norvegicus (rat))
University Of Catania

Curated by ChEMBL
LigandPNGBDBM50438661(CHEMBL2414451)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of Sprague-Dawley rat spleen microsomal HO-1 assessed as bilirubin formation after 60 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeme oxygenase 1(Rattus norvegicus (rat))
University Of Catania

Curated by ChEMBL
LigandPNGBDBM50438653(CHEMBL2414450)
Affinity DataIC50:  6.90E+4nMAssay Description:Inhibition of Sprague-Dawley rat spleen microsomal HO-1 assessed as bilirubin formation after 60 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeme oxygenase 1(Rattus norvegicus (rat))
University Of Catania

Curated by ChEMBL
LigandPNGBDBM50438662(CHEMBL2414449)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of Sprague-Dawley rat spleen microsomal HO-1 assessed as bilirubin formation after 60 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeme oxygenase 1(Rattus norvegicus (rat))
University Of Catania

Curated by ChEMBL
LigandPNGBDBM50438654(CHEMBL2414448)
Affinity DataIC50:  5.60E+4nMAssay Description:Inhibition of Sprague-Dawley rat spleen microsomal HO-1 assessed as bilirubin formation after 60 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeme oxygenase 1(Rattus norvegicus (rat))
University Of Catania

Curated by ChEMBL
LigandPNGBDBM50438663(CHEMBL1452451)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of Sprague-Dawley rat spleen microsomal HO-1 assessed as bilirubin formation after 60 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeme oxygenase 1(Rattus norvegicus (rat))
University Of Catania

Curated by ChEMBL
LigandPNGBDBM50438664(CHEMBL2414447)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of Sprague-Dawley rat spleen microsomal HO-1 assessed as bilirubin formation after 60 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeme oxygenase 1(Rattus norvegicus (rat))
University Of Catania

Curated by ChEMBL
LigandPNGBDBM50438655(CHEMBL2414446)
Affinity DataIC50:  9.20E+4nMAssay Description:Inhibition of Sprague-Dawley rat spleen microsomal HO-1 assessed as bilirubin formation after 60 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeme oxygenase 1(Rattus norvegicus (rat))
University Of Catania

Curated by ChEMBL
LigandPNGBDBM50438656(CHEMBL2414445)
Affinity DataIC50:  2.10E+4nMAssay Description:Inhibition of Sprague-Dawley rat spleen microsomal HO-1 assessed as bilirubin formation after 60 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeme oxygenase 1(Rattus norvegicus (rat))
University Of Catania

Curated by ChEMBL
LigandPNGBDBM50438665(CHEMBL2414444)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of Sprague-Dawley rat spleen microsomal HO-1 assessed as bilirubin formation after 60 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeme oxygenase 1(Rattus norvegicus (rat))
University Of Catania

Curated by ChEMBL
LigandPNGBDBM50438657(CHEMBL1363752)
Affinity DataIC50:  3.10E+4nMAssay Description:Inhibition of Sprague-Dawley rat spleen microsomal HO-1 assessed as bilirubin formation after 60 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeme oxygenase 1(Rattus norvegicus (rat))
University Of Catania

Curated by ChEMBL
LigandPNGBDBM50271549(1-(4-(3-bromophenoxy)butyl)-1H-imidazole | CHEMBL4...)
Affinity DataIC50:  2.10E+3nMAssay Description:Inhibition of Sprague-Dawley rat spleen microsomal HO-1 assessed as bilirubin formation after 60 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeme oxygenase 1(Rattus norvegicus (rat))
University Of Catania

Curated by ChEMBL
LigandPNGBDBM84805(1-azolyl-4-phenyl-2-butanone, 7)
Affinity DataIC50:  2.60E+3nMAssay Description:Inhibition of Sprague-Dawley rat spleen microsomal HO-1 assessed as bilirubin formation after 60 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeme oxygenase 1(Rattus norvegicus (rat))
University Of Catania

Curated by ChEMBL
LigandPNGBDBM50438658(CHEMBL1188560)
Affinity DataIC50:  60nMAssay Description:Inhibition of Sprague-Dawley rat spleen microsomal HO-1 assessed as bilirubin formation after 60 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeme oxygenase 1(Rattus norvegicus (rat))
University Of Catania

Curated by ChEMBL
LigandPNGBDBM50240895(2-(1H-Imidazol-1-yl)-1-(4-nitrophenyl)ethanone | 2...)
Affinity DataIC50:  2.50E+3nMAssay Description:Inhibition of Sprague-Dawley rat spleen microsomal HO-1 assessed as bilirubin formation after 60 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeme oxygenase 1(Rattus norvegicus (rat))
University Of Catania

Curated by ChEMBL
LigandPNGBDBM50044424(4-(((2S,4S)-2-((1H-imidazol-1-yl)methyl)-2-(4-chlo...)
Affinity DataIC50:  5.50E+3nMAssay Description:Inhibition of Sprague-Dawley rat spleen microsomal HO-1 assessed as bilirubin formation after 60 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeme oxygenase 1(Rattus norvegicus (rat))
University Of Catania

Curated by ChEMBL
LigandPNGBDBM31652(imidazole-dioxolane, 3)
Affinity DataIC50:  1.03E+3nMpH: 7.4 T: 2°CAssay Description:HO activity in rat spleen (HO-1) and brain (HO-2) microsomal fractions was determined by the quantitation of CO formed from the degradation of methem...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeme oxygenase 1(Rattus norvegicus (rat))
University Of Catania

Curated by ChEMBL
LigandPNGBDBM31653(CHEMBL421109 | imidazole-dioxolane, 5)
Affinity DataIC50:  330nMpH: 7.4 T: 2°CAssay Description:HO activity in rat spleen (HO-1) and brain (HO-2) microsomal fractions was determined by the quantitation of CO formed from the degradation of methem...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeme oxygenase 1(Rattus norvegicus (rat))
University Of Catania

Curated by ChEMBL
LigandPNGBDBM31654(CHEMBL368045 | imidazole-dioxolane, 6)
Affinity DataIC50:  4.00E+3nMpH: 7.4 T: 2°CAssay Description:HO activity in rat spleen (HO-1) and brain (HO-2) microsomal fractions was determined by the quantitation of CO formed from the degradation of methem...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeme oxygenase 1(Rattus norvegicus (rat))
University Of Catania

Curated by ChEMBL
LigandPNGBDBM31655(CHEMBL179494 | imidazole-dioxolane, 7)
Affinity DataIC50:  4.00E+3nMpH: 7.4 T: 2°CAssay Description:HO activity in rat spleen (HO-1) and brain (HO-2) microsomal fractions was determined by the quantitation of CO formed from the degradation of methem...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeme oxygenase 1(Rattus norvegicus (rat))
University Of Catania

Curated by ChEMBL
LigandPNGBDBM31656(imidazole-dioxolane, 8)
Affinity DataIC50:  2.50E+4nMpH: 7.4 T: 2°CAssay Description:HO activity in rat spleen (HO-1) and brain (HO-2) microsomal fractions was determined by the quantitation of CO formed from the degradation of methem...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeme oxygenase 1(Rattus norvegicus (rat))
University Of Catania

Curated by ChEMBL
LigandPNGBDBM31657(imidazole-dioxolane, 9)
Affinity DataIC50:  1.59E+3nMpH: 7.4 T: 2°CAssay Description:HO activity in rat spleen (HO-1) and brain (HO-2) microsomal fractions was determined by the quantitation of CO formed from the degradation of methem...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeme oxygenase 1(Rattus norvegicus (rat))
University Of Catania

Curated by ChEMBL
LigandPNGBDBM31658(imidazole-dioxolane, 10)
Affinity DataIC50:  2.10E+3nMpH: 7.4 T: 2°CAssay Description:HO activity in rat spleen (HO-1) and brain (HO-2) microsomal fractions was determined by the quantitation of CO formed from the degradation of methem...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeme oxygenase 1(Rattus norvegicus (rat))
University Of Catania

Curated by ChEMBL
LigandPNGBDBM31659(imidazole-dioxolane, 11)
Affinity DataIC50:  700nMpH: 7.4 T: 2°CAssay Description:HO activity in rat spleen (HO-1) and brain (HO-2) microsomal fractions was determined by the quantitation of CO formed from the degradation of methem...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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