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Found 4 Enz. Inhib. hit(s) with Target = 'Histidine protein kinase SaeS'
TargetHistidine protein kinase SaeS(Staphylococcus aureus (strain NCTC 8325))
University Of Southampton

Curated by ChEMBL
LigandPNGBDBM50468034(CHEMBL4286992)
Affinity DataKd:  6.80E+3nMAssay Description:Binding affinity to Staphylococcus aureus SaeS kinase domain after 15 mins by fluorescence spectrophotometryMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistidine protein kinase SaeS(Staphylococcus aureus (strain NCTC 8325))
University Of Southampton

Curated by ChEMBL
LigandPNGBDBM76798((E)-1-[2,4-dihydroxy-3-[(2E)-6-hydroxy-3,7-dimethy...)
Affinity DataKd:  4.00E+4nMAssay Description:Binding affinity to Staphylococcus aureus SaeS kinase domain after 15 mins by fluorescence spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistidine protein kinase SaeS(Staphylococcus aureus (strain NCTC 8325))
University Of Southampton

Curated by ChEMBL
LigandPNGBDBM50468034(CHEMBL4286992)
Affinity DataIC50:  1.60E+5nMAssay Description:Inhibition of recombinant Staphylococcus aureus SaeS autophosphorylation expressed in Escherichia coli BL21(DE3) preincubated for 15 mins followed by...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistidine protein kinase SaeS(Staphylococcus aureus (strain NCTC 8325))
University Of Southampton

Curated by ChEMBL
LigandPNGBDBM76798((E)-1-[2,4-dihydroxy-3-[(2E)-6-hydroxy-3,7-dimethy...)
Affinity DataIC50:  2.20E+5nMAssay Description:Inhibition of recombinant Staphylococcus aureus SaeS autophosphorylation expressed in Escherichia coli BL21(DE3) preincubated for 15 mins followed by...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed