Found 514 Enz. Inhib. hit(s) with Target = 'L-lactate dehydrogenase B chain' 
Affinity DataKd: 1.10E+4nMAssay Description:Binding affinity to truncated human N-terminal His6-tagged LDH-H expressed in Escherichia coli Rosetta (DE3) after 5 mins by Red-NHS fluorescence dye...More data for this Ligand-Target Pair
Affinity DataKd: 2.50E+4nMAssay Description:Binding affinity to truncated human N-terminal His6-tagged LDH-H expressed in Escherichia coli Rosetta (DE3) after 5 mins by Red-NHS fluorescence dye...More data for this Ligand-Target Pair
Affinity DataKd: 6.40E+4nMAssay Description:Binding affinity to truncated human N-terminal His6-tagged LDH-H expressed in Escherichia coli Rosetta (DE3) after 5 mins by Red-NHS fluorescence dye...More data for this Ligand-Target Pair
Affinity DataKd: 6.70E+4nMAssay Description:Binding affinity to truncated human N-terminal His6-tagged LDH-H expressed in Escherichia coli Rosetta (DE3) after 5 mins by Red-NHS fluorescence dye...More data for this Ligand-Target Pair
Affinity DataKd: 1.13E+5nMAssay Description:Binding affinity to truncated human N-terminal His6-tagged LDH-H expressed in Escherichia coli Rosetta (DE3) after 5 mins by Red-NHS fluorescence dye...More data for this Ligand-Target Pair
Affinity DataKd: 1.42E+5nMAssay Description:Binding affinity to truncated human N-terminal His6-tagged LDH-H expressed in Escherichia coli Rosetta (DE3) after 5 mins by Red-NHS fluorescence dye...More data for this Ligand-Target Pair
Affinity DataKd: 3.80E+5nMAssay Description:Competitive binding affinity to recombinant full length human His-tagged LDH-1 (1 to 322 residues) expressed in Escherichia coli assessed as protein-...More data for this Ligand-Target Pair
Affinity DataKd: 3.98E+5nMAssay Description:Binding affinity to truncated human N-terminal His6-tagged LDH-H expressed in Escherichia coli Rosetta (DE3) after 5 mins by Red-NHS fluorescence dye...More data for this Ligand-Target Pair
Affinity DataKd: 4.65E+5nMAssay Description:Binding affinity to truncated human N-terminal His6-tagged LDH-H expressed in Escherichia coli Rosetta (DE3) after 5 mins by Red-NHS fluorescence dye...More data for this Ligand-Target Pair
Affinity DataKd: 7.87E+5nMAssay Description:Binding affinity to truncated human N-terminal His6-tagged LDH-H expressed in Escherichia coli Rosetta (DE3) after 5 mins by Red-NHS fluorescence dye...More data for this Ligand-Target Pair
Affinity DataKd: >1.00E+6nMAssay Description:Binding affinity to truncated human N-terminal His6-tagged LDH-H expressed in Escherichia coli Rosetta (DE3) after 5 mins by Red-NHS fluorescence dye...More data for this Ligand-Target Pair
Affinity DataKd: >1.00E+6nMAssay Description:Binding affinity to truncated human N-terminal His6-tagged LDH-H expressed in Escherichia coli Rosetta (DE3) after 5 mins by Red-NHS fluorescence dye...More data for this Ligand-Target Pair
Affinity DataKd: >1.00E+6nMAssay Description:Binding affinity to truncated human N-terminal His6-tagged LDH-H expressed in Escherichia coli Rosetta (DE3) after 5 mins by Red-NHS fluorescence dye...More data for this Ligand-Target Pair
Affinity DataKd: 1.02E+6nMAssay Description:Binding affinity to full length human N-terminal His6-tagged LDH-H expressed in Escherichia coli Rosetta (DE3) in sodium phosphate buffer at pH 7.6 b...More data for this Ligand-Target Pair
Affinity DataKd: 1.05E+6nMAssay Description:Binding affinity to full length human N-terminal His6-tagged LDH-H expressed in Escherichia coli Rosetta (DE3) in sodium phosphate buffer at pH 7.6 b...More data for this Ligand-Target Pair
Affinity DataKd: 1.05E+6nMAssay Description:Binding affinity to truncated human N-terminal His6-tagged LDH-H expressed in Escherichia coli Rosetta (DE3) after 5 mins by Red-NHS fluorescence dye...More data for this Ligand-Target Pair
Affinity DataKd: 1.49E+6nMAssay Description:Binding affinity to full length human N-terminal His6-tagged LDH-H expressed in Escherichia coli Rosetta (DE3) in sodium phosphate buffer at pH 7.6 b...More data for this Ligand-Target Pair
Affinity DataKd: 1.78E+6nMAssay Description:Binding affinity to full length human N-terminal His6-tagged LDH-H expressed in Escherichia coli Rosetta (DE3) measured after 5 mins by Red-NHS fluor...More data for this Ligand-Target Pair
Affinity DataKi: 50nMAssay Description:inhibitory activity against Human Lactate Dehydrogenase (LDH-M)More data for this Ligand-Target Pair
Affinity DataKi: 100nMAssay Description:inhibitory activity against Human Lactate Dehydrogenase (LDH-M)More data for this Ligand-Target Pair
Affinity DataKi: 200nMAssay Description:inhibitory activity against Human Lactate Dehydrogenase (LDH-M)More data for this Ligand-Target Pair
Affinity DataKi: 400nMAssay Description:Competitive inhibition of human LDH1 in presence of NADHMore data for this Ligand-Target Pair
Affinity DataKi: 500nMAssay Description:inhibitory activity against Human Lactate Dehydrogenase (LDH-M)More data for this Ligand-Target Pair
Affinity DataKi: 700nMAssay Description:Non-competitive inhibition of human recombinant LDHB assessed as inhibition constant using varying concentration of pyruvate as substrate preincubate...More data for this Ligand-Target Pair
Affinity DataKi: 700nMAssay Description:Competitive inhibition of human LDH1 in presence of NADHMore data for this Ligand-Target Pair
Affinity DataKi: 1.00E+3nMAssay Description:Competitive inhibition of human LDH1 in presence of NADHMore data for this Ligand-Target Pair
Affinity DataKi: 1.00E+3nMAssay Description:inhibitory activity against Human Lactate Dehydrogenase (LDH-H)More data for this Ligand-Target Pair
Affinity DataKi: 1.00E+3nMAssay Description:inhibitory activity against Human Lactate Dehydrogenase (LDH-M)More data for this Ligand-Target Pair
TargetL-lactate dehydrogenase B chain(Mus musculus (Mouse))
Sapienza University Of Rome
Curated by ChEMBL
Sapienza University Of Rome
Curated by ChEMBL
Affinity DataKi: 1.40E+3nMAssay Description:Inhibition of mouse LDHB using sodium pyruvate as substrateMore data for this Ligand-Target Pair
Affinity DataKi: 1.40E+3nMAssay Description:Competitive inhibition of human LDH1 in presence of NADHMore data for this Ligand-Target Pair
Affinity DataKi: 2.00E+3nMAssay Description:Mixed inhibition of human recombinant LDHB assessed as inhibition constant using varying concentration of pyruvate as substrate preincubated for 10 m...More data for this Ligand-Target Pair
Affinity DataKi: 2.00E+3nMAssay Description:inhibitory activity against Human Lactate Dehydrogenase (LDH-M)More data for this Ligand-Target Pair
Affinity DataKi: 3.00E+3nMAssay Description:inhibitory activity against Human Lactate Dehydrogenase (LDH-M)More data for this Ligand-Target Pair
Affinity DataKi: 4.00E+3nMAssay Description:inhibitory activity against Human Lactate Dehydrogenase (LDH-M)More data for this Ligand-Target Pair
Affinity DataKi: 5.10E+3nMAssay Description:Non-competitive inhibition of human recombinant LDHB assessed as inhibition constant using varying concentration of pyruvate as substrate preincubate...More data for this Ligand-Target Pair
Affinity DataKi: 7.00E+3nMAssay Description:inhibitory activity against Human Lactate Dehydrogenase (LDH-H)More data for this Ligand-Target Pair
Affinity DataKi: 7.00E+3nMAssay Description:Competitive inhibition of human LDH1 in presence of NADHMore data for this Ligand-Target Pair
Affinity DataKi: 8.00E+3nMAssay Description:Competitive inhibition of human LDH1 in presence of NADHMore data for this Ligand-Target Pair
Affinity DataKi: 8.00E+3nMAssay Description:Competitive inhibition of human LDH1 in presence of NADHMore data for this Ligand-Target Pair
Affinity DataKi: 1.29E+4nMAssay Description:Non-competitive inhibition of human recombinant LDHB assessed as inhibition constant using varying concentration of pyruvate as substrate preincubate...More data for this Ligand-Target Pair
Affinity DataKi: 1.30E+4nMAssay Description:inhibitory activity against Human Lactate Dehydrogenase (LDH-M)More data for this Ligand-Target Pair
Affinity DataKi: 1.51E+4nMAssay Description:Inhibition of LDHB in human heart using pyruvate as substrate incubated for 3 mins by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataKi: 1.51E+4nMAssay Description:Competitive inhibition of human LDH1 meaured for 3 mins in presence of pyruvate by fluorescence analysisMore data for this Ligand-Target Pair
Affinity DataKi: 1.90E+4nMAssay Description:inhibitory activity against Human Lactate Dehydrogenase (LDH-H)More data for this Ligand-Target Pair
Affinity DataKi: 1.90E+4nMAssay Description:Competitive inhibition of human LDH1 in presence of NADHMore data for this Ligand-Target Pair
Affinity DataKi: 2.32E+4nMAssay Description:Competitive inhibition of human LDH1 meaured for 3 mins in presence of NADH by fluorescence analysisMore data for this Ligand-Target Pair
TargetL-lactate dehydrogenase B chain(Sus scrofa)
University Of Rochester Medical Center
Curated by ChEMBL
University Of Rochester Medical Center
Curated by ChEMBL
Affinity DataKi: 2.52E+4nMAssay Description:In vitro inhibitory activity against pig heart lactate dehydrogenase (LDH)More data for this Ligand-Target Pair
Affinity DataKi: 3.30E+4nMAssay Description:Competitive inhibition of human LDH1 in presence of NADHMore data for this Ligand-Target Pair
Affinity DataKi: 3.40E+4nMAssay Description:inhibitory activity against Human Lactate Dehydrogenase (LDH-M)More data for this Ligand-Target Pair
Affinity DataKi: 3.40E+4nMAssay Description:Competitive inhibition of human LDH1 in presence of NADHMore data for this Ligand-Target Pair
