Found 482 Enz. Inhib. hit(s) with Target = 'Microtubule-associated protein tau' 
Affinity DataKd: 0.700nMAssay Description:Binding affinity to heparin induced human Tau 441 at 50 pM to 500 nM after 30 minsMore data for this Ligand-Target Pair
Affinity DataKd: 44.8nMAssay Description:Binding affinity to recombinant human tau expressed in Escherichia coli after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataKd: 50nMAssay Description:Binding affinity human recombinant tau (243 to 375) expressed in Escherichia coli BL21(DE3)RIL after 1 hr by scintillation countingMore data for this Ligand-Target Pair
Affinity DataKd: 80nMAssay Description:(A) Expression and Purification of Human Tau: 1 mM IPTG (Sangon Biotech, Cat. No A100487) was used to induce production of tau by bacteria (BL21, Inv...More data for this Ligand-Target Pair
Affinity DataKd: 100nMAssay Description:(A) Expression and Purification of Human Tau: 1 mM IPTG (Sangon Biotech, Cat. No A100487) was used to induce production of tau by bacteria (BL21, Inv...More data for this Ligand-Target Pair
Affinity DataKd: 110nMAssay Description:(A) Expression and Purification of Human Tau: 1 mM IPTG (Sangon Biotech, Cat. No A100487) was used to induce production of tau by bacteria (BL21, Inv...More data for this Ligand-Target Pair
Affinity DataKd: 120nMAssay Description:(A) Expression and Purification of Human Tau: 1 mM IPTG (Sangon Biotech, Cat. No A100487) was used to induce production of tau by bacteria (BL21, Inv...More data for this Ligand-Target Pair
Affinity DataKd: 150nMAssay Description:(A) Expression and Purification of Human Tau: 1 mM IPTG (Sangon Biotech, Cat. No A100487) was used to induce production of tau by bacteria (BL21, Inv...More data for this Ligand-Target Pair
Affinity DataKd: 230nMAssay Description:(A) Expression and Purification of Human Tau: 1 mM IPTG (Sangon Biotech, Cat. No A100487) was used to induce production of tau by bacteria (BL21, Inv...More data for this Ligand-Target Pair
Affinity DataKd: 300nMAssay Description:Binding affinity to recombinant human tau (441 amino acid residues) aggregates expressed in Escherichia coli assessed as apparent dissociation consta...More data for this Ligand-Target Pair
Affinity DataKd: 394nMAssay Description:Binding affinity to N-terminal His-tagged recombinant human Tau40 expressed in Escherichia coli Rosetta (DE3) assessed as dissociation constant incub...More data for this Ligand-Target Pair
Affinity DataKd: 450nMAssay Description:Binding affinity to recombinant human tau (441 amino acid residues) aggregates expressed in Escherichia coli assessed as apparent dissociation consta...More data for this Ligand-Target Pair
Affinity DataKd: 470nMAssay Description:(A) Expression and Purification of Human Tau: 1 mM IPTG (Sangon Biotech, Cat. No A100487) was used to induce production of tau by bacteria (BL21, Inv...More data for this Ligand-Target Pair
Affinity DataKd: 550nMAssay Description:(A) Expression and Purification of Human Tau: 1 mM IPTG (Sangon Biotech, Cat. No A100487) was used to induce production of tau by bacteria (BL21, Inv...More data for this Ligand-Target Pair
Affinity DataKd: 763nMAssay Description:Binding affinity to human Tau (1 to 441 residues) by ITC methodMore data for this Ligand-Target Pair
Affinity DataKd: 2.36E+3nMAssay Description:Binding affinity to recombinant human tau (441 amino acid residues) aggregates expressed in Escherichia coli assessed as apparent dissociation consta...More data for this Ligand-Target Pair
Affinity DataKi: 0.180nM ΔG°: -55.6kJ/molepH: 7.4 T: 2°CAssay Description:For displacement tau binding assay, unlabeled test compounds were dissolved in DMSO at 1 mM. Dilutions of tests compounds to various concentrations w...More data for this Ligand-Target Pair
Affinity DataKi: 0.220nM ΔG°: -55.1kJ/molepH: 7.4 T: 2°CAssay Description:For displacement tau binding assay, unlabeled test compounds were dissolved in DMSO at 1 mM. Dilutions of tests compounds to various concentrations w...More data for this Ligand-Target Pair
Affinity DataKi: 0.224nM ΔG°: -55.1kJ/molepH: 7.4 T: 2°CAssay Description:For displacement tau binding assay, unlabeled test compounds were dissolved in DMSO at 1 mM. Dilutions of tests compounds to various concentrations w...More data for this Ligand-Target Pair
Affinity DataKi: 0.290nM ΔG°: -54.4kJ/molepH: 7.4 T: 2°CAssay Description:For displacement tau binding assay, unlabeled test compounds were dissolved in DMSO at 1 mM. Dilutions of tests compounds to various concentrations w...More data for this Ligand-Target Pair
Affinity DataKi: 0.290nM ΔG°: -54.4kJ/molepH: 7.4 T: 2°CAssay Description:For displacement tau binding assay, unlabeled test compounds were dissolved in DMSO at 1 mM. Dilutions of tests compounds to various concentrations w...More data for this Ligand-Target Pair
Affinity DataKi: 0.320nM ΔG°: -54.2kJ/molepH: 7.4 T: 2°CAssay Description:For displacement tau binding assay, unlabeled test compounds were dissolved in DMSO at 1 mM. Dilutions of tests compounds to various concentrations w...More data for this Ligand-Target Pair
Affinity DataKi: 0.330nM ΔG°: -54.1kJ/molepH: 7.4 T: 2°CAssay Description:For displacement tau binding assay, unlabeled test compounds were dissolved in DMSO at 1 mM. Dilutions of tests compounds to various concentrations w...More data for this Ligand-Target Pair
Affinity DataKi: 0.330nM ΔG°: -54.1kJ/molepH: 7.4 T: 2°CAssay Description:For displacement tau binding assay, unlabeled test compounds were dissolved in DMSO at 1 mM. Dilutions of tests compounds to various concentrations w...More data for this Ligand-Target Pair
Affinity DataKi: 0.383nM ΔG°: -53.7kJ/molepH: 7.4 T: 2°CAssay Description:For displacement tau binding assay, unlabeled test compounds were dissolved in DMSO at 1 mM. Dilutions of tests compounds to various concentrations w...More data for this Ligand-Target Pair
Affinity DataKi: 0.400nM ΔG°: -53.6kJ/molepH: 7.4 T: 2°CAssay Description:For displacement tau binding assay, unlabeled test compounds were dissolved in DMSO at 1 mM. Dilutions of tests compounds to various concentrations w...More data for this Ligand-Target Pair
Affinity DataKi: 0.410nM ΔG°: -53.6kJ/molepH: 7.4 T: 2°CAssay Description:For displacement tau binding assay, unlabeled test compounds were dissolved in DMSO at 1 mM. Dilutions of tests compounds to various concentrations w...More data for this Ligand-Target Pair
Affinity DataKi: 0.423nM ΔG°: -53.5kJ/molepH: 7.4 T: 2°CAssay Description:For displacement tau binding assay, unlabeled test compounds were dissolved in DMSO at 1 mM. Dilutions of tests compounds to various concentrations w...More data for this Ligand-Target Pair
Affinity DataKi: 0.430nM ΔG°: -53.5kJ/molepH: 7.4 T: 2°CAssay Description:For displacement tau binding assay, unlabeled test compounds were dissolved in DMSO at 1 mM. Dilutions of tests compounds to various concentrations w...More data for this Ligand-Target Pair
Affinity DataKi: 0.430nM ΔG°: -53.5kJ/molepH: 7.4 T: 2°CAssay Description:For displacement tau binding assay, unlabeled test compounds were dissolved in DMSO at 1 mM. Dilutions of tests compounds to various concentrations w...More data for this Ligand-Target Pair
Affinity DataKi: 0.438nM ΔG°: -53.4kJ/molepH: 7.4 T: 2°CAssay Description:For displacement tau binding assay, unlabeled test compounds were dissolved in DMSO at 1 mM. Dilutions of tests compounds to various concentrations w...More data for this Ligand-Target Pair
Affinity DataKi: 0.480nMAssay Description:Displacement of Thioflavin S from recombinant human tau expressed in Escherichia coli after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.480nM ΔG°: -53.2kJ/molepH: 7.4 T: 2°CAssay Description:For displacement tau binding assay, unlabeled test compounds were dissolved in DMSO at 1 mM. Dilutions of tests compounds to various concentrations w...More data for this Ligand-Target Pair
Affinity DataKi: 0.480nM ΔG°: -53.2kJ/molepH: 7.4 T: 2°CAssay Description:For displacement tau binding assay, unlabeled test compounds were dissolved in DMSO at 1 mM. Dilutions of tests compounds to various concentrations w...More data for this Ligand-Target Pair
Affinity DataKi: 0.494nM ΔG°: -53.1kJ/molepH: 7.4 T: 2°CAssay Description:For displacement tau binding assay, unlabeled test compounds were dissolved in DMSO at 1 mM. Dilutions of tests compounds to various concentrations w...More data for this Ligand-Target Pair
Affinity DataKi: 0.512nM ΔG°: -53.0kJ/molepH: 7.4 T: 2°CAssay Description:For displacement tau binding assay, unlabeled test compounds were dissolved in DMSO at 1 mM. Dilutions of tests compounds to various concentrations w...More data for this Ligand-Target Pair
Affinity DataKi: 0.530nM ΔG°: -52.9kJ/molepH: 7.4 T: 2°CAssay Description:For displacement tau binding assay, unlabeled test compounds were dissolved in DMSO at 1 mM. Dilutions of tests compounds to various concentrations w...More data for this Ligand-Target Pair
Affinity DataKi: 0.530nM ΔG°: -52.9kJ/molepH: 7.4 T: 2°CAssay Description:For displacement tau binding assay, unlabeled test compounds were dissolved in DMSO at 1 mM. Dilutions of tests compounds to various concentrations w...More data for this Ligand-Target Pair
Affinity DataKi: 0.540nM ΔG°: -52.9kJ/molepH: 7.4 T: 2°CAssay Description:For displacement tau binding assay, unlabeled test compounds were dissolved in DMSO at 1 mM. Dilutions of tests compounds to various concentrations w...More data for this Ligand-Target Pair
Affinity DataKi: 0.550nM ΔG°: -52.9kJ/molepH: 7.4 T: 2°CAssay Description:For displacement tau binding assay, unlabeled test compounds were dissolved in DMSO at 1 mM. Dilutions of tests compounds to various concentrations w...More data for this Ligand-Target Pair
Affinity DataKi: 0.620nM ΔG°: -52.6kJ/molepH: 7.4 T: 2°CAssay Description:For displacement tau binding assay, unlabeled test compounds were dissolved in DMSO at 1 mM. Dilutions of tests compounds to various concentrations w...More data for this Ligand-Target Pair
Affinity DataKi: 0.670nM ΔG°: -52.4kJ/molepH: 7.4 T: 2°CAssay Description:For displacement tau binding assay, unlabeled test compounds were dissolved in DMSO at 1 mM. Dilutions of tests compounds to various concentrations w...More data for this Ligand-Target Pair
Affinity DataKi: 0.672nM ΔG°: -52.4kJ/molepH: 7.4 T: 2°CAssay Description:For displacement tau binding assay, unlabeled test compounds were dissolved in DMSO at 1 mM. Dilutions of tests compounds to various concentrations w...More data for this Ligand-Target Pair
Affinity DataKi: 0.677nM ΔG°: -52.3kJ/molepH: 7.4 T: 2°CAssay Description:For displacement tau binding assay, unlabeled test compounds were dissolved in DMSO at 1 mM. Dilutions of tests compounds to various concentrations w...More data for this Ligand-Target Pair
Affinity DataKi: 0.690nM ΔG°: -52.3kJ/molepH: 7.4 T: 2°CAssay Description:For displacement tau binding assay, unlabeled test compounds were dissolved in DMSO at 1 mM. Dilutions of tests compounds to various concentrations w...More data for this Ligand-Target Pair
Affinity DataKi: 0.75nM ΔG°: -52.1kJ/molepH: 7.4 T: 2°CAssay Description:For displacement tau binding assay, unlabeled test compounds were dissolved in DMSO at 1 mM. Dilutions of tests compounds to various concentrations w...More data for this Ligand-Target Pair
Affinity DataKi: 0.75nM ΔG°: -52.1kJ/molepH: 7.4 T: 2°CAssay Description:For displacement tau binding assay, unlabeled test compounds were dissolved in DMSO at 1 mM. Dilutions of tests compounds to various concentrations w...More data for this Ligand-Target Pair
Affinity DataKi: 0.760nM ΔG°: -52.0kJ/molepH: 7.4 T: 2°CAssay Description:For displacement tau binding assay, unlabeled test compounds were dissolved in DMSO at 1 mM. Dilutions of tests compounds to various concentrations w...More data for this Ligand-Target Pair
Affinity DataKi: 0.784nM ΔG°: -52.0kJ/molepH: 7.4 T: 2°CAssay Description:For displacement tau binding assay, unlabeled test compounds were dissolved in DMSO at 1 mM. Dilutions of tests compounds to various concentrations w...More data for this Ligand-Target Pair
Affinity DataKi: 0.870nM ΔG°: -51.7kJ/molepH: 7.4 T: 2°CAssay Description:For displacement tau binding assay, unlabeled test compounds were dissolved in DMSO at 1 mM. Dilutions of tests compounds to various concentrations w...More data for this Ligand-Target Pair
