Found 4301 Enz. Inhib. hit(s) with Target = 'Muscarinic acetylcholine receptor M3' 
Affinity DataKd: 0.0100nMAssay Description:Antagonist activity at human recombinant muscarinic M3 receptor expressed in CHO cells assessed as inhibition of acetylcholine-induced calcium mobili...More data for this Ligand-Target Pair
Affinity DataKd: 0.0200nMAssay Description:Antagonist activity at human recombinant muscarinic M3 receptor expressed in CHO cells assessed as inhibition of acetylcholine-induced intracellular ...More data for this Ligand-Target Pair
Affinity DataKd: 0.0251nMAssay Description:Antagonist potency at human muscarinic acetylcholine M3 receptor expressed in CHO cells assessed as inhibition of Ach-induced calcium mobilization by...More data for this Ligand-Target Pair
Affinity DataKd: 0.0316nMAssay Description:Antagonist activity at human recombinant muscarinic M3 receptor expressed in CHO cells assessed as inhibition of acetylcholine-induced calcium mobili...More data for this Ligand-Target Pair
Affinity DataKd: 0.0398nMAssay Description:Antagonist potency at human muscarinic acetylcholine M3 receptor expressed in CHO cells assessed as inhibition of Ach-induced calcium mobilization by...More data for this Ligand-Target Pair
Affinity DataKd: 0.0501nMAssay Description:Antagonist potency at human muscarinic acetylcholine M3 receptor expressed in CHO cells assessed as inhibition of Ach-induced calcium mobilization by...More data for this Ligand-Target Pair
Affinity DataKd: 0.0501nMAssay Description:Antagonist potency at human muscarinic acetylcholine M3 receptor expressed in CHO cells assessed as inhibition of Ach-induced calcium mobilization by...More data for this Ligand-Target Pair
Affinity DataKd: 0.0501nMAssay Description:Antagonist potency at human muscarinic acetylcholine M3 receptor expressed in CHO cells assessed as inhibition of Ach-induced calcium mobilization by...More data for this Ligand-Target Pair
Affinity DataKd: 0.0631nMAssay Description:Antagonist activity at human recombinant muscarinic M3 receptor expressed in CHO cells assessed as inhibition of acetylcholine-induced calcium mobili...More data for this Ligand-Target Pair
Affinity DataKd: 0.0794nMAssay Description:Antagonist potency at human muscarinic acetylcholine M3 receptor expressed in CHO cells assessed as inhibition of Ach-induced calcium mobilization by...More data for this Ligand-Target Pair
Affinity DataKd: 0.0794nMAssay Description:Antagonist activity at human recombinant muscarinic M3 receptor expressed in CHO cells assessed as inhibition of acetylcholine-induced calcium mobili...More data for this Ligand-Target Pair
Affinity DataKd: 0.0794nMAssay Description:Antagonist activity at human recombinant muscarinic M3 receptor expressed in CHO cells assessed as inhibition of acetylcholine-induced calcium mobili...More data for this Ligand-Target Pair
Affinity DataKd: 0.100nMAssay Description:Antagonist activity at human recombinant muscarinic M3 receptor expressed in CHO cells assessed as inhibition of acetylcholine-induced calcium mobili...More data for this Ligand-Target Pair
Affinity DataKd: 0.100nMAssay Description:Antagonist activity at human recombinant muscarinic M3 receptor expressed in CHO cells assessed as inhibition of acetylcholine-induced intracellular ...More data for this Ligand-Target Pair
Affinity DataKd: 0.100nMAssay Description:Antagonist activity at human recombinant muscarinic M3 receptor expressed in CHO cells assessed as inhibition of acetylcholine-induced intracellular ...More data for this Ligand-Target Pair
Affinity DataKd: 0.120nMAssay Description:Displacement of [3H]N-methylscopolamine from human muscarinic acetylcholine M3 receptor stably expressed in CHO cells by radioligand competition bind...More data for this Ligand-Target Pair
Affinity DataKd: 0.120nMAssay Description:Displacement of [3H]N-methylscopolamine from human muscarinic acetylcholine M3 receptor stably expressed in CHO cells by radioligand competition bind...More data for this Ligand-Target Pair
Affinity DataKd: 0.120nMAssay Description:Displacement of [3H]N-methylscopolamine from human muscarinic acetylcholine M3 receptor stably expressed in CHO cells by radioligand competition bind...More data for this Ligand-Target Pair
Affinity DataKd: 0.120nMAssay Description:Displacement of [3H]N-methylscopolamine from human muscarinic acetylcholine M3 receptor stably expressed in CHO cells by radioligand competition bind...More data for this Ligand-Target Pair
Affinity DataKd: 0.126nMAssay Description:Antagonist activity at human recombinant muscarinic M3 receptor expressed in CHO cells assessed as inhibition of acetylcholine-induced calcium mobili...More data for this Ligand-Target Pair
Affinity DataKd: 0.126nMAssay Description:Antagonist activity at human recombinant muscarinic M3 receptor expressed in CHO cells assessed as inhibition of acetylcholine-induced intracellular ...More data for this Ligand-Target Pair
Affinity DataKd: 0.126nMAssay Description:Antagonist activity at human recombinant muscarinic M3 receptor expressed in CHO cells assessed as inhibition of acetylcholine-induced calcium mobili...More data for this Ligand-Target Pair
Affinity DataKd: 0.158nMAssay Description:Antagonist activity at human recombinant muscarinic M3 receptor expressed in CHO cells assessed as inhibition of acetylcholine-induced calcium mobili...More data for this Ligand-Target Pair
Affinity DataKd: 0.158nMAssay Description:Antagonist activity at human recombinant muscarinic M3 receptor expressed in CHO cells assessed as inhibition of acetylcholine-induced calcium mobili...More data for this Ligand-Target Pair
Affinity DataKd: 0.158nMAssay Description:Antagonist potency at human muscarinic acetylcholine M3 receptor expressed in CHO cells assessed as inhibition of Ach-induced calcium mobilization by...More data for this Ligand-Target Pair
Affinity DataKd: 0.158nMAssay Description:Antagonist potency at human muscarinic acetylcholine M3 receptor expressed in CHO cells assessed as inhibition of Ach-induced calcium mobilization by...More data for this Ligand-Target Pair
Affinity DataKd: 0.200nMAssay Description:Antagonist activity at human recombinant muscarinic M3 receptor expressed in CHO cells assessed as inhibition of acetylcholine-induced calcium mobili...More data for this Ligand-Target Pair
Affinity DataKd: 0.251nMAssay Description:Antagonist activity at human recombinant muscarinic M3 receptor expressed in CHO cells assessed as inhibition of acetylcholine-induced calcium mobili...More data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M3 [1-273,470-589,N6Q,N15Q,N41Q,N48Q,N52Q](Rattus norvegicus (Rat))
National Institutes Of Health
National Institutes Of Health
Affinity DataKd: 0.403nMpH: 7.4Assay Description:In brief, binding reactions containing ~10 μg of membrane protein per tube were carried out for 2 h (22 °C) in 1 ml of binding buffer containing...More data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M3 [1-273,470-589,N6Q,N15Q,N41Q,N48Q,N52Q,T552C](Rattus norvegicus (Rat))
National Institutes Of Health
National Institutes Of Health
Affinity DataKd: 0.438nMpH: 7.4Assay Description:In brief, binding reactions containing ~10 μg of membrane protein per tube were carried out for 2 h (22 °C) in 1 ml of binding buffer containing...More data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M3 [1-273,470-589,N6Q,N15Q,N41Q,N48Q,N52Q](Rattus norvegicus (Rat))
National Institutes Of Health
National Institutes Of Health
Affinity DataKd: 0.440nMAssay Description:In brief, membranes from COS-7 cells expressing different Cys-substituted mutant M3R constructs were first treated with CuPhen (100 μM; 10 min a...More data for this Ligand-Target Pair
Affinity DataKd: 0.440nMAssay Description:In vitro receptor binding against Muscarinic acetylcholine receptor M3 in rat submandibular gland was determined using [3H]pirenzepineMore data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M3 [1-273,470-589,N6Q,N15Q,N41Q,N48Q,N52Q,T556C](Rattus norvegicus (Rat))
National Institutes Of Health
National Institutes Of Health
Affinity DataKd: 0.462nMpH: 7.4Assay Description:In brief, binding reactions containing ~10 μg of membrane protein per tube were carried out for 2 h (22 °C) in 1 ml of binding buffer containing...More data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M3 [1-273,470-589,N6Q,N15Q,N41Q,N48Q,N52Q,R176C](Rattus norvegicus (Rat))
National Institutes Of Health
National Institutes Of Health
Affinity DataKd: 0.470nMAssay Description:In brief, membranes from COS-7 cells expressing different Cys-substituted mutant M3R constructs were first treated with CuPhen (100 μM; 10 min a...More data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M3 [1-273,470-589,N6Q,N15Q,N41Q,N48Q,N52Q,R176C](Rattus norvegicus (Rat))
National Institutes Of Health
National Institutes Of Health
Affinity DataKd: 0.484nMpH: 7.4Assay Description:In brief, binding reactions containing ~10 μg of membrane protein per tube were carried out for 2 h (22 °C) in 1 ml of binding buffer containing...More data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M3 [1-273,470-589,N6Q,N15Q,N41Q,N48Q,N52Q,R179C](Rattus norvegicus (Rat))
National Institutes Of Health
National Institutes Of Health
Affinity DataKd: 0.493nMpH: 7.4Assay Description:In brief, binding reactions containing ~10 μg of membrane protein per tube were carried out for 2 h (22 °C) in 1 ml of binding buffer containing...More data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M3 [1-273,470-589,N6Q,N15Q,N41Q,N48Q,N52Q,K178C](Rattus norvegicus (Rat))
National Institutes Of Health
National Institutes Of Health
Affinity DataKd: 0.499nMpH: 7.4Assay Description:In brief, binding reactions containing ~10 μg of membrane protein per tube were carried out for 2 h (22 °C) in 1 ml of binding buffer containing...More data for this Ligand-Target Pair
Affinity DataKd: 0.501nMAssay Description:Antagonist potency at human muscarinic acetylcholine M3 receptor expressed in CHO cells assessed as inhibition of Ach-induced calcium mobilization by...More data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M3 [1-273,470-589,N6Q,N15Q,N41Q,N48Q,N52Q,A177C](Rattus norvegicus (Rat))
National Institutes Of Health
National Institutes Of Health
Affinity DataKd: 0.521nMpH: 7.4Assay Description:In brief, binding reactions containing ~10 μg of membrane protein per tube were carried out for 2 h (22 °C) in 1 ml of binding buffer containing...More data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M3 [1-273,470-589,N6Q,N15Q,N41Q,N48Q,N52Q,R551C](Rattus norvegicus (Rat))
National Institutes Of Health
National Institutes Of Health
Affinity DataKd: 0.524nMpH: 7.4Assay Description:In brief, binding reactions containing ~10 μg of membrane protein per tube were carried out for 2 h (22 °C) in 1 ml of binding buffer containing...More data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M3 [1-273,470-589,N6Q,N15Q,N41Q,N48Q,N52Q,T553C](Rattus norvegicus (Rat))
National Institutes Of Health
National Institutes Of Health
Affinity DataKd: 0.548nMpH: 7.4Assay Description:In brief, binding reactions containing ~10 μg of membrane protein per tube were carried out for 2 h (22 °C) in 1 ml of binding buffer containing...More data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M3 [1-273,470-589,N6Q,N15Q,N41Q,N48Q,N52Q,K555C](Rattus norvegicus (Rat))
National Institutes Of Health
National Institutes Of Health
Affinity DataKd: 0.553nMpH: 7.4Assay Description:In brief, binding reactions containing ~10 μg of membrane protein per tube were carried out for 2 h (22 °C) in 1 ml of binding buffer containing...More data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M3 [1-273,470-589,N6Q,N15Q,N41Q,N48Q,N52Q,K548C](Rattus norvegicus (Rat))
National Institutes Of Health
National Institutes Of Health
Affinity DataKd: 0.555nMpH: 7.4Assay Description:In brief, binding reactions containing ~10 μg of membrane protein per tube were carried out for 2 h (22 °C) in 1 ml of binding buffer containing...More data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M3 [1-273,470-589,N6Q,N15Q,N41Q,N48Q,N52Q](Rattus norvegicus (Rat))
National Institutes Of Health
National Institutes Of Health
Affinity DataKd: 0.555nMpH: 7.4Assay Description:In brief, binding reactions containing ~10 μg of membrane protein per tube were carried out for 2 h (22 °C) in 1 ml of binding buffer containing...More data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M3 [1-273,470-589,N6Q,N15Q,N41Q,N48Q,N52Q,F550C](Rattus norvegicus (Rat))
National Institutes Of Health
National Institutes Of Health
Affinity DataKd: 0.556nMpH: 7.4Assay Description:In brief, binding reactions containing ~10 μg of membrane protein per tube were carried out for 2 h (22 °C) in 1 ml of binding buffer containing...More data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M3 [1-273,470-589,N6Q,N15Q,N41Q,N48Q,N52Q,T549C](Rattus norvegicus (Rat))
National Institutes Of Health
National Institutes Of Health
Affinity DataKd: 0.564nMpH: 7.4Assay Description:In brief, binding reactions containing ~10 μg of membrane protein per tube were carried out for 2 h (22 °C) in 1 ml of binding buffer containing...More data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M3 [1-273,470-589,N6Q,N15Q,N41Q,N48Q,N52Q,F554C](Rattus norvegicus (Rat))
National Institutes Of Health
National Institutes Of Health
Affinity DataKd: 0.583nMpH: 7.4Assay Description:In brief, binding reactions containing ~10 μg of membrane protein per tube were carried out for 2 h (22 °C) in 1 ml of binding buffer containing...More data for this Ligand-Target Pair
Affinity DataKd: 0.630nMAssay Description:In vitro receptor binding against Muscarinic acetylcholine receptor M3 in rat submandibular gland was determined using [3H]pirenzepineMore data for this Ligand-Target Pair
Affinity DataKd: 0.631nMAssay Description:Antagonist activity at human recombinant muscarinic M3 receptor expressed in CHO cells assessed as inhibition of acetylcholine-induced intracellular ...More data for this Ligand-Target Pair
Affinity DataKd: 0.631nMAssay Description:Antagonist activity at human recombinant muscarinic M3 receptor expressed in CHO cells assessed as inhibition of acetylcholine-induced calcium mobili...More data for this Ligand-Target Pair
