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Found 1234 Enz. Inhib. hit(s) with Target = 'Nonstructural protein 5'
TargetNonstructural protein 5A(Hepatitis C virus)
Merck

Curated by ChEMBL
LigandPNGBDBM50147212(CHEMBL3765311 | US11053243, Example 192)
Affinity DataEC50:  2.30nMAssay Description:Inhibition of HCV NS5A Y93H mutant in HCV genotype 1b assessed as reduction in viral replication by cell based replicon assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNonstructural protein 5A(Hepatitis C virus)
Merck

Curated by ChEMBL
LigandPNGBDBM50147212(CHEMBL3765311 | US11053243, Example 192)
Affinity DataEC50:  6.40nMAssay Description:Inhibition of HCV NS5A L31V mutant in HCV genotype 1a assessed as reduction in viral replication by cell based replicon assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNonstructural protein 5A(Hepatitis C virus)
Merck

Curated by ChEMBL
LigandPNGBDBM50271726(CHEMBL3765513)
Affinity DataEC50:  18nMAssay Description:Inhibition of HCV NS5A L31V mutant in HCV genotype 1a assessed as reduction in viral replication by cell based replicon assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNonstructural protein 5A(Hepatitis C virus)
Merck

Curated by ChEMBL
LigandPNGBDBM50271727(CHEMBL3763799)
Affinity DataEC50:  9nMAssay Description:Inhibition of HCV NS5A L31V mutant in HCV genotype 1a assessed as reduction in viral replication by cell based replicon assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNonstructural protein 5A(Hepatitis C virus)
Merck

Curated by ChEMBL
LigandPNGBDBM50147212(CHEMBL3765311 | US11053243, Example 192)
Affinity DataEC50:  8.80nMAssay Description:Inhibition of HCV NS5A Y93C mutant in HCV genotype 1a assessed as reduction in viral replication by cell based replicon assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNonstructural protein 5A(Hepatitis C virus)
Merck

Curated by ChEMBL
LigandPNGBDBM50271726(CHEMBL3765513)
Affinity DataEC50:  2nMAssay Description:Inhibition of HCV NS5A Y93C mutant in HCV genotype 1a assessed as reduction in viral replication by cell based replicon assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNonstructural protein 5A(Hepatitis C virus)
Merck

Curated by ChEMBL
LigandPNGBDBM50271727(CHEMBL3763799)
Affinity DataEC50:  2nMAssay Description:Inhibition of HCV NS5A Y93C mutant in HCV genotype 1a assessed as reduction in viral replication by cell based replicon assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNonstructural protein 5A(Hepatitis C virus)
Merck

Curated by ChEMBL
LigandPNGBDBM50147212(CHEMBL3765311 | US11053243, Example 192)
Affinity DataEC50:  20nMAssay Description:Inhibition of HCV NS5A Y93H mutant in HCV genotype 1a assessed as reduction in viral replication by cell based replicon assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNonstructural protein 5A(Hepatitis C virus)
Merck

Curated by ChEMBL
LigandPNGBDBM50271726(CHEMBL3765513)
Affinity DataEC50:  49nMAssay Description:Inhibition of HCV NS5A Y93H mutant in HCV genotype 1a assessed as reduction in viral replication by cell based replicon assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNonstructural protein 5A(Hepatitis C virus)
Merck

Curated by ChEMBL
LigandPNGBDBM50271727(CHEMBL3763799)
Affinity DataEC50:  47nMAssay Description:Inhibition of HCV NS5A Y93H mutant in HCV genotype 1a assessed as reduction in viral replication by cell based replicon assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNonstructural protein 5A(Hepatitis C virus)
Merck

Curated by ChEMBL
LigandPNGBDBM50147212(CHEMBL3765311 | US11053243, Example 192)
Affinity DataEC50:  0.5nMAssay Description:Inhibition of HCV NS5A L31V mutant in HCV genotype 1b assessed as reduction in viral replication by cell based replicon assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNonstructural protein 5A(Hepatitis C virus)
Merck

Curated by ChEMBL
LigandPNGBDBM50271726(CHEMBL3765513)
Affinity DataEC50:  0.0300nMAssay Description:Inhibition of HCV NS5A L31V mutant in HCV genotype 1b assessed as reduction in viral replication by cell based replicon assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNonstructural protein 5A(Hepatitis C virus)
Merck

Curated by ChEMBL
LigandPNGBDBM50271727(CHEMBL3763799)
Affinity DataEC50:  0.0200nMAssay Description:Inhibition of HCV NS5A L31V mutant in HCV genotype 1b assessed as reduction in viral replication by cell based replicon assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNonstructural protein 5A(Hepatitis C virus)
Merck

Curated by ChEMBL
LigandPNGBDBM50271726(CHEMBL3765513)
Affinity DataEC50:  0.0200nMAssay Description:Inhibition of HCV NS5A Y93H mutant in HCV genotype 1b assessed as reduction in viral replication by cell based replicon assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNonstructural protein 5A(Hepatitis C virus)
Merck

Curated by ChEMBL
LigandPNGBDBM50271727(CHEMBL3763799)
Affinity DataEC50:  0.0100nMAssay Description:Inhibition of HCV NS5A Y93H mutant in HCV genotype 1b assessed as reduction in viral replication by cell based replicon assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNonstructural protein 5A(Hepatitis C virus)
Merck

Curated by ChEMBL
LigandPNGBDBM50147212(CHEMBL3765311 | US11053243, Example 192)
Affinity DataEC50:  8.5nMAssay Description:Inhibition of HCV NS5A Q30R mutant in HCV genotype 1a assessed as reduction in viral replication by cell based replicon assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNonstructural protein 5A(Hepatitis C virus)
Merck

Curated by ChEMBL
LigandPNGBDBM50271727(CHEMBL3763799)
Affinity DataEC50:  2nMAssay Description:Inhibition of HCV NS5A Q30H mutant in HCV genotype 1a assessed as reduction in viral replication by cell based replicon assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNonstructural protein 5A(Hepatitis C virus)
Merck

Curated by ChEMBL
LigandPNGBDBM50271726(CHEMBL3765513)
Affinity DataEC50:  4nMAssay Description:Inhibition of HCV NS5A Q30H mutant in HCV genotype 1a assessed as reduction in viral replication by cell based replicon assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNonstructural protein 5A(Hepatitis C virus)
Merck

Curated by ChEMBL
LigandPNGBDBM50147212(CHEMBL3765311 | US11053243, Example 192)
Affinity DataEC50:  5.5nMAssay Description:Inhibition of HCV NS5A Q30H mutant in HCV genotype 1a assessed as reduction in viral replication by cell based replicon assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNonstructural protein 5A(Hepatitis C virus)
Merck

Curated by ChEMBL
LigandPNGBDBM50271727(CHEMBL3763799)
Affinity DataEC50:  0.0900nMAssay Description:Inhibition of HCV NS5A M28V mutant in HCV genotype 1a assessed as reduction in viral replication by cell based replicon assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNonstructural protein 5A(Hepatitis C virus)
Merck

Curated by ChEMBL
LigandPNGBDBM50147212(CHEMBL3765311 | US11053243, Example 192)
Affinity DataEC50:  0.00400nMAssay Description:Inhibition of HCV NS5A M28V mutant in HCV genotype 1a assessed as reduction in viral replication by cell based replicon assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNonstructural protein 5A(Hepatitis C virus)
Merck

Curated by ChEMBL
LigandPNGBDBM50271727(CHEMBL3763799)
Affinity DataEC50:  0.0200nMAssay Description:Inhibition of HCV NS5A in HCV genotype 4a assessed as reduction in viral replication by cell based replicon assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNonstructural protein 5A(Hepatitis C virus)
Merck

Curated by ChEMBL
LigandPNGBDBM50271726(CHEMBL3765513)
Affinity DataEC50:  0.0500nMAssay Description:Inhibition of HCV NS5A in HCV genotype 4a assessed as reduction in viral replication by cell based replicon assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNonstructural protein 5A(Hepatitis C virus)
Merck

Curated by ChEMBL
LigandPNGBDBM50271727(CHEMBL3763799)
Affinity DataEC50:  0.200nMAssay Description:Inhibition of HCV NS5A in HCV genotype 3a assessed as reduction in viral replication by cell based replicon assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNonstructural protein 5A(Hepatitis C virus)
Merck

Curated by ChEMBL
LigandPNGBDBM50271726(CHEMBL3765513)
Affinity DataEC50:  0.25nMAssay Description:Inhibition of HCV NS5A in HCV genotype 3a assessed as reduction in viral replication by cell based replicon assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNonstructural protein 5A(Hepatitis C virus)
Merck

Curated by ChEMBL
LigandPNGBDBM50271727(CHEMBL3763799)
Affinity DataEC50:  77nMAssay Description:Inhibition of HCV NS5A in HCV genotype 2b assessed as reduction in viral replication by cell based replicon assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNonstructural protein 5A(Hepatitis C virus)
Merck

Curated by ChEMBL
LigandPNGBDBM50271726(CHEMBL3765513)
Affinity DataEC50:  125nMAssay Description:Inhibition of HCV NS5A in HCV genotype 2b assessed as reduction in viral replication by cell based replicon assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNonstructural protein 5A(Hepatitis C virus)
Merck

Curated by ChEMBL
LigandPNGBDBM50147212(CHEMBL3765311 | US11053243, Example 192)
Affinity DataEC50:  286nMAssay Description:Inhibition of HCV NS5A in HCV genotype 2b assessed as reduction in viral replication by cell based replicon assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNonstructural protein 5A(Hepatitis C virus)
Merck

Curated by ChEMBL
LigandPNGBDBM50271726(CHEMBL3765513)
Affinity DataEC50:  0.00300nMAssay Description:Inhibition of HCV NS5A in HCV genotype 2a assessed as reduction in viral replication by cell based replicon assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNonstructural protein 5A(Hepatitis C virus)
Merck

Curated by ChEMBL
LigandPNGBDBM50147212(CHEMBL3765311 | US11053243, Example 192)
Affinity DataEC50:  0.400nMAssay Description:Inhibition of HCV NS5A in HCV genotype 2a assessed as reduction in viral replication by cell based replicon assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNonstructural protein 5A(Hepatitis C virus)
Merck

Curated by ChEMBL
LigandPNGBDBM50271727(CHEMBL3763799)
Affinity DataEC50:  0.00100nMAssay Description:Inhibition of HCV NS5A in HCV genotype 1b assessed as reduction in viral replication by cell based replicon assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNonstructural protein 5A(Hepatitis C virus)
Merck

Curated by ChEMBL
LigandPNGBDBM50147212(CHEMBL3765311 | US11053243, Example 192)
Affinity DataEC50:  0.00100nMAssay Description:Inhibition of HCV NS5A in HCV genotype 1b assessed as reduction in viral replication by cell based replicon assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNonstructural protein 5A(Hepatitis C virus)
Merck

Curated by ChEMBL
LigandPNGBDBM50271727(CHEMBL3763799)
Affinity DataEC50:  0.00900nMAssay Description:Inhibition of HCV NS5A in HCV genotype 1a assessed as reduction in viral replication by cell based replicon assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNonstructural protein 5A(Hepatitis C virus)
Merck

Curated by ChEMBL
LigandPNGBDBM50271726(CHEMBL3765513)
Affinity DataEC50:  0.0150nMAssay Description:Inhibition of HCV NS5A in HCV genotype 1a assessed as reduction in viral replication by cell based replicon assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNonstructural protein 5A(Hepatitis C virus)
Merck

Curated by ChEMBL
LigandPNGBDBM50271726(CHEMBL3765513)
Affinity DataEC50:  18nMAssay Description:Inhibition of HCV NS5A Q30R mutant in HCV genotype 1a assessed as reduction in viral replication by cell based replicon assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNonstructural protein 5A(Hepatitis C virus)
Merck

Curated by ChEMBL
LigandPNGBDBM50271727(CHEMBL3763799)
Affinity DataEC50:  6nMAssay Description:Inhibition of HCV NS5A Q30R mutant in HCV genotype 1a assessed as reduction in viral replication by cell based replicon assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNonstructural protein 5A(Hepatitis C virus)
Merck

Curated by ChEMBL
LigandPNGBDBM50271726(CHEMBL3765513)
Affinity DataEC50:  0.100nMAssay Description:Inhibition of HCV NS5A M28V mutant in HCV genotype 1a assessed as reduction in viral replication by cell based replicon assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNonstructural protein 5A(Hepatitis C virus)
Merck

Curated by ChEMBL
LigandPNGBDBM50147212(CHEMBL3765311 | US11053243, Example 192)
Affinity DataEC50:  0.300nMAssay Description:Inhibition of HCV NS5A in HCV genotype 4a assessed as reduction in viral replication by cell based replicon assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNonstructural protein 5A(Hepatitis C virus)
Merck

Curated by ChEMBL
LigandPNGBDBM50147212(CHEMBL3765311 | US11053243, Example 192)
Affinity DataEC50:  4nMAssay Description:Inhibition of HCV NS5A in HCV genotype 3a assessed as reduction in viral replication by cell based replicon assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNonstructural protein 5A(Hepatitis C virus)
Merck

Curated by ChEMBL
LigandPNGBDBM50271727(CHEMBL3763799)
Affinity DataEC50:  0.00200nMAssay Description:Inhibition of HCV NS5A in HCV genotype 2a assessed as reduction in viral replication by cell based replicon assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNonstructural protein 5A(Hepatitis C virus)
Merck

Curated by ChEMBL
LigandPNGBDBM50271726(CHEMBL3765513)
Affinity DataEC50:  0.00100nMAssay Description:Inhibition of HCV NS5A in HCV genotype 1b assessed as reduction in viral replication by cell based replicon assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNonstructural protein 5A(Hepatitis C virus)
Merck

Curated by ChEMBL
LigandPNGBDBM50147212(CHEMBL3765311 | US11053243, Example 192)
Affinity DataEC50:  0.0100nMAssay Description:Inhibition of HCV NS5A in HCV genotype 1a assessed as reduction in viral replication by cell based replicon assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNonstructural protein 5A(Hepatitis C virus)
Merck

Curated by ChEMBL
LigandPNGBDBM50453104(CHEMBL3915742)
Affinity DataEC50:  0.151nMAssay Description:Inhibition of NS5A in HuH7 cell infected HCV genotype 1a H77 assessed as decrease in viral replication after 3 days in presence of 40% human plasma b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNonstructural protein 5A(Hepatitis C virus)
Merck

Curated by ChEMBL
LigandPNGBDBM50453108(CHEMBL4202479)
Affinity DataEC50:  0.0750nMAssay Description:Inhibition of NS5A in HuH7 cell infected HCV genotype 1a H77 assessed as decrease in viral replication after 3 days in presence of 40% human plasma b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNonstructural protein 5A(Hepatitis C virus)
Merck

Curated by ChEMBL
LigandPNGBDBM50453110(CHEMBL3127327)
Affinity DataEC50:  0.136nMAssay Description:Inhibition of NS5A in HuH7 cell infected HCV genotype 1a H77 assessed as decrease in viral replication after 3 days by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNonstructural protein 5A(Hepatitis C virus)
Merck

Curated by ChEMBL
LigandPNGBDBM50453100(A-1325912.0 | ABT-530 | Pibrentasvir)
Affinity DataEC50:  0.0640nMAssay Description:Inhibition of NS5A in HuH7 cell infected HCV genotype 1a H77 assessed as decrease in viral replication after 3 days in presence of 40% human plasma b...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNonstructural protein 5A(Hepatitis C virus)
Merck

Curated by ChEMBL
LigandPNGBDBM50453116(CHEMBL4215187)
Affinity DataEC50:  0.220nMAssay Description:Inhibition of NS5A in HuH7 cell infected HCV genotype 1a H77 assessed as decrease in viral replication after 3 days in presence of 40% human plasma b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNonstructural protein 5A(Hepatitis C virus)
Merck

Curated by ChEMBL
LigandPNGBDBM50453118(CHEMBL4204257)
Affinity DataEC50:  0.0780nMAssay Description:Inhibition of NS5A in HuH7 cell infected HCV genotype 1a H77 assessed as decrease in viral replication after 3 days in presence of 40% human plasma b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNonstructural protein 5A(Hepatitis C virus)
Merck

Curated by ChEMBL
LigandPNGBDBM50453106(CHEMBL4215923)
Affinity DataEC50:  0.0760nMAssay Description:Inhibition of NS5A in HuH7 cell infected HCV genotype 1a H77 assessed as decrease in viral replication after 3 days in presence of 40% human plasma b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNonstructural protein 5A(Hepatitis C virus)
Merck

Curated by ChEMBL
LigandPNGBDBM50453115(CHEMBL4203712)
Affinity DataEC50:  0.213nMAssay Description:Inhibition of NS5A in HuH7 cell infected HCV genotype 1a H77 assessed as decrease in viral replication after 3 days in presence of 40% human plasma b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
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