TargetPeptidyl-prolyl cis-trans isomerase D(Homo sapiens (Human))
University Of Liverpool
Curated by ChEMBL
University Of Liverpool
Curated by ChEMBL
Affinity DataKd: 13nMAssay Description:Binding affinity to Cyclophilin D (unknown origin) by isothermal titration calorimetryMore data for this Ligand-Target Pair
TargetPeptidyl-prolyl cis-trans isomerase D(Homo sapiens (Human))
University Of Liverpool
Curated by ChEMBL
University Of Liverpool
Curated by ChEMBL
Affinity DataKd: 30nMAssay Description:Binding affinity to CypD (unknown origin) assessed as dissociation constant by SPR analysisMore data for this Ligand-Target Pair
TargetPeptidyl-prolyl cis-trans isomerase D(Homo sapiens (Human))
University Of Liverpool
Curated by ChEMBL
University Of Liverpool
Curated by ChEMBL
Affinity DataKd: 101nMAssay Description:Inhibition of cyclosporin binding to Cyp40 by flourescence polarization competition assayMore data for this Ligand-Target Pair
TargetPeptidyl-prolyl cis-trans isomerase D(Homo sapiens (Human))
University Of Liverpool
Curated by ChEMBL
University Of Liverpool
Curated by ChEMBL
Affinity DataKd: 149nMAssay Description:Binding affinity to human recombinant cyclophilin D by surface plasmon resonance analysisMore data for this Ligand-Target Pair
TargetPeptidyl-prolyl cis-trans isomerase D(Homo sapiens (Human))
University Of Liverpool
Curated by ChEMBL
University Of Liverpool
Curated by ChEMBL
Affinity DataKd: 230nMAssay Description:Binding affinity to CypD (unknown origin) assessed as dissociation constant by SPR analysisMore data for this Ligand-Target Pair
TargetPeptidyl-prolyl cis-trans isomerase D(Homo sapiens (Human))
University Of Liverpool
Curated by ChEMBL
University Of Liverpool
Curated by ChEMBL
Affinity DataKd: 410nMAssay Description:Binding affinity to Cyclophilin D (unknown origin) by isothermal titration calorimetryMore data for this Ligand-Target Pair
TargetPeptidyl-prolyl cis-trans isomerase D(Homo sapiens (Human))
University Of Liverpool
Curated by ChEMBL
University Of Liverpool
Curated by ChEMBL
Affinity DataKd: 1.20E+3nMAssay Description:Binding affinity to Cyclophilin D (unknown origin) by isothermal titration calorimetryMore data for this Ligand-Target Pair
TargetPeptidyl-prolyl cis-trans isomerase D(Homo sapiens (Human))
University Of Liverpool
Curated by ChEMBL
University Of Liverpool
Curated by ChEMBL
Affinity DataKd: 2.80E+3nMAssay Description:Binding affinity to Cyclophilin D (unknown origin) by isothermal titration calorimetryMore data for this Ligand-Target Pair
TargetPeptidyl-prolyl cis-trans isomerase D(Homo sapiens (Human))
University Of Liverpool
Curated by ChEMBL
University Of Liverpool
Curated by ChEMBL
Affinity DataKd: 5.12E+3nMAssay Description:Binding affinity to Cyclophilin D (unknown origin) by isothermal titration calorimetryMore data for this Ligand-Target Pair
TargetPeptidyl-prolyl cis-trans isomerase D(Homo sapiens (Human))
University Of Liverpool
Curated by ChEMBL
University Of Liverpool
Curated by ChEMBL
Affinity DataKd: 5.40E+3nMAssay Description:Binding affinity to Cyclophilin D (unknown origin) by isothermal titration calorimetryMore data for this Ligand-Target Pair
TargetPeptidyl-prolyl cis-trans isomerase D(Homo sapiens (Human))
University Of Liverpool
Curated by ChEMBL
University Of Liverpool
Curated by ChEMBL
Affinity DataKd: 8.80E+3nMAssay Description:Binding affinity to Cyclophilin D (unknown origin) by isothermal titration calorimetryMore data for this Ligand-Target Pair
TargetPeptidyl-prolyl cis-trans isomerase D(Homo sapiens (Human))
University Of Liverpool
Curated by ChEMBL
University Of Liverpool
Curated by ChEMBL
Affinity DataKd: 1.00E+4nMAssay Description:Binding affinity to Cyclophilin D (unknown origin) by isothermal titration calorimetryMore data for this Ligand-Target Pair
TargetPeptidyl-prolyl cis-trans isomerase D(Homo sapiens (Human))
University Of Liverpool
Curated by ChEMBL
University Of Liverpool
Curated by ChEMBL
Affinity DataKd: 2.27E+4nMAssay Description:Binding affinity to Cyclophilin D (unknown origin) by isothermal titration calorimetryMore data for this Ligand-Target Pair
TargetPeptidyl-prolyl cis-trans isomerase D(Homo sapiens (Human))
University Of Liverpool
Curated by ChEMBL
University Of Liverpool
Curated by ChEMBL
Affinity DataKd: 3.41E+4nMAssay Description:Binding affinity to Cyclophilin D (unknown origin) by isothermal titration calorimetryMore data for this Ligand-Target Pair
TargetPeptidyl-prolyl cis-trans isomerase D(Homo sapiens (Human))
University Of Liverpool
Curated by ChEMBL
University Of Liverpool
Curated by ChEMBL
Affinity DataKd: 5.76E+4nMAssay Description:Binding affinity to Cyclophilin D (unknown origin) by isothermal titration calorimetryMore data for this Ligand-Target Pair
TargetPeptidyl-prolyl cis-trans isomerase D(Homo sapiens (Human))
University Of Liverpool
Curated by ChEMBL
University Of Liverpool
Curated by ChEMBL
Affinity DataKd: 8.20E+4nMAssay Description:Binding affinity to Cyclophilin D (unknown origin) by isothermal titration calorimetryMore data for this Ligand-Target Pair
TargetPeptidyl-prolyl cis-trans isomerase D(Homo sapiens (Human))
University Of Liverpool
Curated by ChEMBL
University Of Liverpool
Curated by ChEMBL
Affinity DataKd: 9.25E+4nMAssay Description:Binding affinity to Cyclophilin D (unknown origin) by isothermal titration calorimetryMore data for this Ligand-Target Pair
TargetPeptidyl-prolyl cis-trans isomerase D(Homo sapiens (Human))
University Of Liverpool
Curated by ChEMBL
University Of Liverpool
Curated by ChEMBL
Affinity DataKd: 9.73E+4nMAssay Description:Binding affinity to Cyclophilin D (unknown origin) by isothermal titration calorimetryMore data for this Ligand-Target Pair
TargetPeptidyl-prolyl cis-trans isomerase D(Homo sapiens (Human))
University Of Liverpool
Curated by ChEMBL
University Of Liverpool
Curated by ChEMBL
Affinity DataKd: 9.73E+4nMAssay Description:Binding affinity to Cyclophilin D (unknown origin) by isothermal titration calorimetryMore data for this Ligand-Target Pair
TargetPeptidyl-prolyl cis-trans isomerase D(Homo sapiens (Human))
University Of Liverpool
Curated by ChEMBL
University Of Liverpool
Curated by ChEMBL
Affinity DataKd: 1.27E+5nMAssay Description:Binding affinity to Cyclophilin D (unknown origin) by isothermal titration calorimetryMore data for this Ligand-Target Pair
TargetPeptidyl-prolyl cis-trans isomerase D(Homo sapiens (Human))
University Of Liverpool
Curated by ChEMBL
University Of Liverpool
Curated by ChEMBL
Affinity DataKi: 2.60nMAssay Description:Binding affinity to human recombinant cyclophilin D by surface plasmon resonance analysisMore data for this Ligand-Target Pair
TargetPeptidyl-prolyl cis-trans isomerase D(Homo sapiens (Human))
University Of Liverpool
Curated by ChEMBL
University Of Liverpool
Curated by ChEMBL
Affinity DataKi: 7nMAssay Description:Inhibition of fluorescein labeled cyclosporin binding to Cyp40 by flourescence polarization competition assayMore data for this Ligand-Target Pair
TargetPeptidyl-prolyl cis-trans isomerase D(Homo sapiens (Human))
University Of Liverpool
Curated by ChEMBL
University Of Liverpool
Curated by ChEMBL
Affinity DataKi: 8.20nMAssay Description:Inhibition of Cyclophilin D (unknown origin) activity in absence of detergentMore data for this Ligand-Target Pair
TargetPeptidyl-prolyl cis-trans isomerase D(Homo sapiens (Human))
University Of Liverpool
Curated by ChEMBL
University Of Liverpool
Curated by ChEMBL
Affinity DataKi: 12nMAssay Description:Inhibition of Cyclophilin 40 PPIase activityMore data for this Ligand-Target Pair
TargetPeptidyl-prolyl cis-trans isomerase D(Homo sapiens (Human))
University Of Liverpool
Curated by ChEMBL
University Of Liverpool
Curated by ChEMBL
Affinity DataKi: 34nMAssay Description:Inhibition of Cyclophilin 40 PPIase activityMore data for this Ligand-Target Pair
TargetPeptidyl-prolyl cis-trans isomerase D(Homo sapiens (Human))
University Of Liverpool
Curated by ChEMBL
University Of Liverpool
Curated by ChEMBL
Affinity DataKi: 99nMAssay Description:Inhibition of Cyclophilin D (unknown origin) activity preincubated for 15 mins followed Suc-AAPF-pNA substrate addition by chymotrypsin coupled based...More data for this Ligand-Target Pair
TargetPeptidyl-prolyl cis-trans isomerase D(Homo sapiens (Human))
University Of Liverpool
Curated by ChEMBL
University Of Liverpool
Curated by ChEMBL
Affinity DataKi: 950nMAssay Description:Inhibition of Cyclophilin D (unknown origin) activity preincubated for 15 mins followed Suc-AAPF-pNA substrate addition by chymotrypsin coupled based...More data for this Ligand-Target Pair
TargetPeptidyl-prolyl cis-trans isomerase D(Homo sapiens (Human))
University Of Liverpool
Curated by ChEMBL
University Of Liverpool
Curated by ChEMBL
Affinity DataKi: 1.33E+3nMAssay Description:Binding affinity to human recombinant cyclophilin D by surface plasmon resonance analysisMore data for this Ligand-Target Pair
TargetPeptidyl-prolyl cis-trans isomerase D(Homo sapiens (Human))
University Of Liverpool
Curated by ChEMBL
University Of Liverpool
Curated by ChEMBL
Affinity DataKi: 2.42E+3nM ΔG°: -29.9kJ/molepH: 7.8 T: 2°CAssay Description:PPIase activity assay were performed at 283 K in quartz cuvettes with a path length of 1 cm under vigorous stirring with a Hewlett-Packard 8453A UV-v...More data for this Ligand-Target Pair
TargetPeptidyl-prolyl cis-trans isomerase D(Homo sapiens (Human))
University Of Liverpool
Curated by ChEMBL
University Of Liverpool
Curated by ChEMBL
Affinity DataKi: 2.60E+3nMAssay Description:Inhibition of Cyclophilin D (unknown origin) activity preincubated for 15 mins followed Suc-AAPF-pNA substrate addition by chymotrypsin coupled based...More data for this Ligand-Target Pair
TargetPeptidyl-prolyl cis-trans isomerase D(Homo sapiens (Human))
University Of Liverpool
Curated by ChEMBL
University Of Liverpool
Curated by ChEMBL
Affinity DataKi: 4.90E+3nMAssay Description:Inhibition of Cyclophilin D (unknown origin) activity preincubated for 15 mins followed Suc-AAPF-pNA substrate addition by chymotrypsin coupled based...More data for this Ligand-Target Pair
TargetPeptidyl-prolyl cis-trans isomerase D(Homo sapiens (Human))
University Of Liverpool
Curated by ChEMBL
University Of Liverpool
Curated by ChEMBL
Affinity DataKi: 5.90E+3nMAssay Description:Inhibition of Cyclophilin D (unknown origin) activity in absence of detergentMore data for this Ligand-Target Pair
TargetPeptidyl-prolyl cis-trans isomerase D(Homo sapiens (Human))
University Of Liverpool
Curated by ChEMBL
University Of Liverpool
Curated by ChEMBL
Affinity DataKi: 5.90E+3nMAssay Description:Inhibition of Cyclophilin D (unknown origin) activity preincubated for 15 mins followed Suc-AAPF-pNA substrate addition by chymotrypsin coupled based...More data for this Ligand-Target Pair
TargetPeptidyl-prolyl cis-trans isomerase D(Homo sapiens (Human))
University Of Liverpool
Curated by ChEMBL
University Of Liverpool
Curated by ChEMBL
Affinity DataKi: 6.28E+3nM ΔG°: -27.7kJ/molepH: 7.8 T: 2°CAssay Description:PPIase activity assay were performed at 283 K in quartz cuvettes with a path length of 1 cm under vigorous stirring with a Hewlett-Packard 8453A UV-v...More data for this Ligand-Target Pair
TargetPeptidyl-prolyl cis-trans isomerase D(Homo sapiens (Human))
University Of Liverpool
Curated by ChEMBL
University Of Liverpool
Curated by ChEMBL
Affinity DataKi: 9.10E+3nMAssay Description:Inhibition of Cyclophilin D (unknown origin) activity preincubated for 15 mins followed Suc-AAPF-pNA substrate addition by chymotrypsin coupled based...More data for this Ligand-Target Pair
TargetPeptidyl-prolyl cis-trans isomerase D(Homo sapiens (Human))
University Of Liverpool
Curated by ChEMBL
University Of Liverpool
Curated by ChEMBL
Affinity DataKi: 2.20E+4nMAssay Description:Inhibition of Cyclophilin D (unknown origin) activity preincubated for 15 mins followed Suc-AAPF-pNA substrate addition by chymotrypsin coupled based...More data for this Ligand-Target Pair
TargetPeptidyl-prolyl cis-trans isomerase D(Homo sapiens (Human))
University Of Liverpool
Curated by ChEMBL
University Of Liverpool
Curated by ChEMBL
Affinity DataKi: 6.30E+4nMAssay Description:Inhibition of Cyclophilin D (unknown origin) activity preincubated for 15 mins followed Suc-AAPF-pNA substrate addition by chymotrypsin coupled based...More data for this Ligand-Target Pair
TargetPeptidyl-prolyl cis-trans isomerase D(Homo sapiens (Human))
University Of Liverpool
Curated by ChEMBL
University Of Liverpool
Curated by ChEMBL
Affinity DataIC50: 3.00E+4nMpH: 7.8 T: 2°CAssay Description:Cyclophilin PPlase activity was measured at 20 C. by using the standard chymotrypsin coupled assay (Kofron J L, Kuzmic P, Kishore V, Colon-Bonilla E,...More data for this Ligand-Target Pair
TargetPeptidyl-prolyl cis-trans isomerase D(Homo sapiens (Human))
University Of Liverpool
Curated by ChEMBL
University Of Liverpool
Curated by ChEMBL
Affinity DataIC50: 6.20E+3nMpH: 7.8 T: 2°CAssay Description:Cyclophilin PPlase activity was measured at 20 C. by using the standard chymotrypsin coupled assay (Kofron J L, Kuzmic P, Kishore V, Colon-Bonilla E,...More data for this Ligand-Target Pair
TargetPeptidyl-prolyl cis-trans isomerase D(Homo sapiens (Human))
University Of Liverpool
Curated by ChEMBL
University Of Liverpool
Curated by ChEMBL
Affinity DataIC50: 1.14E+4nMpH: 7.8 T: 2°CAssay Description:Cyclophilin PPlase activity was measured at 20 C. by using the standard chymotrypsin coupled assay (Kofron J L, Kuzmic P, Kishore V, Colon-Bonilla E,...More data for this Ligand-Target Pair
TargetPeptidyl-prolyl cis-trans isomerase D(Homo sapiens (Human))
University Of Liverpool
Curated by ChEMBL
University Of Liverpool
Curated by ChEMBL
Affinity DataIC50: 1.40E+3nMpH: 7.8 T: 2°CAssay Description:Cyclophilin PPlase activity was measured at 20 C. by using the standard chymotrypsin coupled assay (Kofron J L, Kuzmic P, Kishore V, Colon-Bonilla E,...More data for this Ligand-Target Pair
TargetPeptidyl-prolyl cis-trans isomerase D(Homo sapiens (Human))
University Of Liverpool
Curated by ChEMBL
University Of Liverpool
Curated by ChEMBL
Affinity DataIC50: 6.20E+3nMpH: 7.8 T: 2°CAssay Description:Cyclophilin PPlase activity was measured at 20 C. by using the standard chymotrypsin coupled assay (Kofron J L, Kuzmic P, Kishore V, Colon-Bonilla E,...More data for this Ligand-Target Pair
TargetPeptidyl-prolyl cis-trans isomerase D(Homo sapiens (Human))
University Of Liverpool
Curated by ChEMBL
University Of Liverpool
Curated by ChEMBL
Affinity DataIC50: 1.10E+3nMpH: 7.8 T: 2°CAssay Description:Cyclophilin PPlase activity was measured at 20 C. by using the standard chymotrypsin coupled assay (Kofron J L, Kuzmic P, Kishore V, Colon-Bonilla E,...More data for this Ligand-Target Pair
TargetPeptidyl-prolyl cis-trans isomerase D(Homo sapiens (Human))
University Of Liverpool
Curated by ChEMBL
University Of Liverpool
Curated by ChEMBL
Affinity DataIC50: 640nMpH: 7.8 T: 2°CAssay Description:Cyclophilin PPlase activity was measured at 20 C. by using the standard chymotrypsin coupled assay (Kofron J L, Kuzmic P, Kishore V, Colon-Bonilla E,...More data for this Ligand-Target Pair
TargetPeptidyl-prolyl cis-trans isomerase D(Homo sapiens (Human))
University Of Liverpool
Curated by ChEMBL
University Of Liverpool
Curated by ChEMBL
Affinity DataIC50: 3.00E+3nMpH: 7.8 T: 2°CAssay Description:Cyclophilin PPlase activity was measured at 20 C. by using the standard chymotrypsin coupled assay (Kofron J L, Kuzmic P, Kishore V, Colon-Bonilla E,...More data for this Ligand-Target Pair
TargetPeptidyl-prolyl cis-trans isomerase D(Homo sapiens (Human))
University Of Liverpool
Curated by ChEMBL
University Of Liverpool
Curated by ChEMBL
Affinity DataIC50: 1.10E+3nMpH: 7.8 T: 2°CAssay Description:Cyclophilin PPlase activity was measured at 20 C. by using the standard chymotrypsin coupled assay (Kofron J L, Kuzmic P, Kishore V, Colon-Bonilla E,...More data for this Ligand-Target Pair
TargetPeptidyl-prolyl cis-trans isomerase D(Homo sapiens (Human))
University Of Liverpool
Curated by ChEMBL
University Of Liverpool
Curated by ChEMBL
Affinity DataIC50: 660nMpH: 7.8 T: 2°CAssay Description:Cyclophilin PPlase activity was measured at 20 C. by using the standard chymotrypsin coupled assay (Kofron J L, Kuzmic P, Kishore V, Colon-Bonilla E,...More data for this Ligand-Target Pair
TargetPeptidyl-prolyl cis-trans isomerase D(Homo sapiens (Human))
University Of Liverpool
Curated by ChEMBL
University Of Liverpool
Curated by ChEMBL
Affinity DataIC50: 3.60nMAssay Description:Inhibition of human recombinant cyclophilin D using Suc-AAPF-MCA as substrate preincubated for 1 hr followed by substrate addition measured per milli...More data for this Ligand-Target Pair
TargetPeptidyl-prolyl cis-trans isomerase D(Homo sapiens (Human))
University Of Liverpool
Curated by ChEMBL
University Of Liverpool
Curated by ChEMBL
Affinity DataIC50: 1.49E+3nMAssay Description:Inhibition of human recombinant cyclophilin D using Suc-AAPF-MCA as substrate preincubated for 1 hr followed by substrate addition measured per milli...More data for this Ligand-Target Pair
TargetPeptidyl-prolyl cis-trans isomerase D(Homo sapiens (Human))
University Of Liverpool
Curated by ChEMBL
University Of Liverpool
Curated by ChEMBL
Affinity DataIC50: <1.00E+4nMAssay Description:The binding capacity of the compounds was measured using a competition Fluorescence-Polarisation based assay with fluorescine labelled cyclosporin.More data for this Ligand-Target Pair