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Found 290 Enz. Inhib. hit(s) with Target = 'Probable global transcription activator SNF2L2'
TargetProbable global transcription activator SNF2L2(Homo sapiens (Human))
University Of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50539801(CHEMBL4648912 | US11840533, Compound 70)
Affinity DataKd: <1nMAssay Description:Binding affinity to human partial length SMARCA2 (S1377 to Q1486 residues) expressed in bacterial expression system by BROMOscan assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProbable global transcription activator SNF2L2(Homo sapiens (Human))
University Of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50469329(CHEMBL4278436)
Affinity DataKd:  13nMAssay Description:Binding affinity to N-terminal MBP-fused human BRM RecA domain (705 to 960 residues) expressed in Escherichia coli BL21 Star (DE3) by ITC methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProbable global transcription activator SNF2L2(Homo sapiens (Human))
University Of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM394530((R)-1-(4-(3-amino-6-(2- | US10308614, Example 131)
Affinity DataKd:  16nMAssay Description:Binding affinity to human SMARCA2 (S1337 to Q1486 residues) expressed in bacterial expression system by bromoscan assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetProbable global transcription activator SNF2L2(Homo sapiens (Human))
University Of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50158688(CHEMBL3752911)
Affinity DataKd:  18nMAssay Description:Binding affinity to human SMARCA2 (S1337 to Q1486 residues) expressed in bacterial expression system by bromoscan assayMore data for this Ligand-Target Pair
TargetProbable global transcription activator SNF2L2(Homo sapiens (Human))
University Of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM394399(US10308614, Example 1 | tert-butyl 4-(3-amino-6-(2...)
Affinity DataKd:  35nMAssay Description:Binding affinity to SMARCA2 (unknown origin) by ITC analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProbable global transcription activator SNF2L2(Homo sapiens (Human))
University Of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50182279(CHEMBL3818070)
Affinity DataKd:  37nMAssay Description:Binding affinity to human SMARCA2 expressed in BL21 (DE3)-R3-BirA cells by isothermal titration calorimetryMore data for this Ligand-Target Pair
TargetProbable global transcription activator SNF2L2(Homo sapiens (Human))
University Of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM394583(2-(6-amino-5-phenylpyridazin-3-yl)phenol | US10308...)
Affinity DataKd:  61nMAssay Description:Binding affinity to human MHHHHHHGSLVPRGS-tagged SMARAC2 isoform B (S1377 to Q1486 residues) by isothermal titration calorimetric assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails PubMed
TargetProbable global transcription activator SNF2L2(Homo sapiens (Human))
University Of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50549126(CHEMBL4793170)
Affinity DataKd:  69nMAssay Description:Binding affinity to SMARCA2 (unknown origin) by ITC analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetProbable global transcription activator SNF2L2(Homo sapiens (Human))
University Of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM394583(2-(6-amino-5-phenylpyridazin-3-yl)phenol | US10308...)
Affinity DataKd:  71nMAssay Description:Binding affinity to human SMARCA2 (S1337 to Q1486 residues) expressed in bacterial expression system by bromoscan assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails PubMed
TargetProbable global transcription activator SNF2L2(Homo sapiens (Human))
University Of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50549127(CHEMBL4790365)
Affinity DataKd:  71nMAssay Description:Binding affinity to SMARCA2 (unknown origin) by ITC analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProbable global transcription activator SNF2L2(Homo sapiens (Human))
University Of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50469323(CHEMBL4290675)
Affinity DataKd:  87nMAssay Description:Binding affinity to N-terminal avi-tagged BRM ATPase-SnAC domain (unknown origin) in absence of ADP by SPR assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProbable global transcription activator SNF2L2(Homo sapiens (Human))
University Of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM394406(2-(6-amino-5-(piperazin- | US10308614, Example 7)
Affinity DataKd:  135nMAssay Description:Binding affinity to SMARCA2 (unknown origin) by ITC analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProbable global transcription activator SNF2L2(Homo sapiens (Human))
University Of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50184979(CHEMBL3822689)
Affinity DataKd:  262nMAssay Description:Binding affinity to His6-tagged human recombinant SMARCA2B bromodomain expressed in Escherichia coli BL21(DE3)-R3-pRARE2 cells by VP-ITC microcalorim...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProbable global transcription activator SNF2L2(Homo sapiens (Human))
University Of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50598934(CHEMBL5183240)
Affinity DataKd:  340nMAssay Description:Binding affinity to human SMARCA2 (S1337 to Q1486 residues) expressed in bacterial expression system by bromoscan assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails PubMed
TargetProbable global transcription activator SNF2L2(Homo sapiens (Human))
University Of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50469323(CHEMBL4290675)
Affinity DataKd:  450nMAssay Description:Binding affinity to N-terminal avi-tagged BRM ATPase-SnAC domain (unknown origin) in presence of ADP by SPR assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProbable global transcription activator SNF2L2(Homo sapiens (Human))
University Of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM394583(2-(6-amino-5-phenylpyridazin-3-yl)phenol | US10308...)
Affinity DataKd:  1.10E+3nMAssay Description:Binding affinity to human MHHHHHHGSLVPRGS-tagged SMARAC2 isoform B L1412P/P1413V/S1414N mutant (S1377 to Q1486 residues) by isothermal titration calo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails PubMed
TargetProbable global transcription activator SNF2L2(Homo sapiens (Human))
University Of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50584925(CHEMBL5079885)
Affinity DataKd: <3.16E+3nMAssay Description:Binding affinity to human SMARCA2 bromodomain assessed as dissociation constant by BROMOscan methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetProbable global transcription activator SNF2L2(Homo sapiens (Human))
University Of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM179481(US9675697, Cpd. No. 73)
Affinity DataKd: >4.00E+3nMAssay Description:Binding affinity to human partial length SMARCA2 (S1377 to Q1486 residues) expressed in bacterial expression system by BROMOscan assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProbable global transcription activator SNF2L2(Homo sapiens (Human))
University Of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50598935(CHEMBL5194650)
Affinity DataKd:  4.40E+3nMAssay Description:Binding affinity to human SMARCA2 (S1337 to Q1486 residues) expressed in bacterial expression system by bromoscan assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetProbable global transcription activator SNF2L2(Homo sapiens (Human))
University Of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50366670(CHEMBL4173488)
Affinity DataKd: >5.00E+3nMAssay Description:Binding affinity to human SMARCA2 (S1377 to Q1486 residues) expressed in bacterial expression system by BROMOScan assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProbable global transcription activator SNF2L2(Homo sapiens (Human))
University Of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50184981(CHEMBL3823055)
Affinity DataKd:  8.10E+3nMAssay Description:Binding affinity to N-terminal His6-TEV-tagged human SMARCA2B transfected in Escherichia coli BL21 (DE3) assessed as dissociation constant at 30 uM b...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetProbable global transcription activator SNF2L2(Homo sapiens (Human))
University Of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM249277(US10017501, Compound 1020-18 | US9458145, 1020-18)
Affinity DataKd: >1.00E+4nMAssay Description:Binding affinity to human partial length SMARCA2 (S1377 to Q1486 residues) expressed in bacterial expression system after 1 hr by bromoscan assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProbable global transcription activator SNF2L2(Homo sapiens (Human))
University Of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50469329(CHEMBL4278436)
Affinity DataKd: >1.00E+4nMAssay Description:Binding affinity to N-terminal MBP-fused human BRM RecA domain E852Q mutant expressed in Escherichia coli BL21 Star (DE3) by ITC methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProbable global transcription activator SNF2L2(Homo sapiens (Human))
University Of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50453949(CHEMBL4208820 | US11247989, Example 87)
Affinity DataKd: >1.00E+4nMAssay Description:Binding affinity to human partial length SMARCA2 (S1377 to Q1486 residues) expressed in bacterial expression system by BROMOscan assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProbable global transcription activator SNF2L2(Homo sapiens (Human))
University Of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50148271(CHEMBL3769590)
Affinity DataKd:  1.58E+4nMAssay Description:Binding affinity to SMARCA2 in human HUT78 cell extract by chemoproteomic competition binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProbable global transcription activator SNF2L2(Homo sapiens (Human))
University Of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50591346(CHEMBL5188924)
Affinity DataKd:  1.59E+4nMAssay Description:Binding affinity to N-terminal His6-TEV-tagged human SMARCA2B transfected in Escherichia coli BL21 (DE3) assessed as dissociation constant at 30 uM b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails PubMed
TargetProbable global transcription activator SNF2L2(Homo sapiens (Human))
University Of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50591358(CHEMBL5204703)
Affinity DataKd:  1.84E+4nMAssay Description:Binding affinity to N-terminal His6-TEV-tagged human SMARCA2B transfected in Escherichia coli BL21 (DE3) assessed as dissociation constant at 30 uM b...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetProbable global transcription activator SNF2L2(Homo sapiens (Human))
University Of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50455480(CHEMBL4218735)
Affinity DataKd: <3.02E+4nMAssay Description:Binding affinity to human partial length DNA-tagged SMARCA2 expressed in bacteria by BROMOscan methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetProbable global transcription activator SNF2L2(Homo sapiens (Human))
University Of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50517156(CHEMBL4559894)
Affinity DataKd: >1.00E+5nMAssay Description:Binding affinity to human partial length SMARCA2 (S1377 to Q1486 residues) expressed in bacterial expression system by BROMOscan assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProbable global transcription activator SNF2L2(Homo sapiens (Human))
University Of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50517166(CHEMBL4527581)
Affinity DataKd: >1.00E+5nMAssay Description:Binding affinity to human partial length SMARCA2 (S1377 to Q1486 residues) expressed in bacterial expression system by BROMOscan assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetProbable global transcription activator SNF2L2(Homo sapiens (Human))
University Of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM96931(MLS000031270 | N,N-Diethyl-2-[5-(3-methoxy-phenyl)...)
Affinity DataEC50:  9.11E+4nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PCBioAssay
TargetProbable global transcription activator SNF2L2(Homo sapiens (Human))
University Of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM96932(Furan-2-carboxylic acid (4-methyl-5-phenylacetylam...)
Affinity DataEC50:  9.12E+4nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PCBioAssay
TargetProbable global transcription activator SNF2L2(Homo sapiens (Human))
University Of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM38858(MLS000035284 | N-(5-Methyl-thiazol-2-yl)-2-(4-pyri...)
Affinity DataEC50:  9.12E+4nMMore data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetProbable global transcription activator SNF2L2(Homo sapiens (Human))
University Of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM96933(7-[4-(2-Methoxy-ethyl)-piperazin-1-yl]-2-(3-methox...)
Affinity DataEC50:  9.11E+4nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PCBioAssay
TargetProbable global transcription activator SNF2L2(Homo sapiens (Human))
University Of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM89178(MLS000078775 | N,N-dimethyl-2-[(2-phenyl-4-benzofu...)
Affinity DataEC50:  1.01E+4nMMore data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetProbable global transcription activator SNF2L2(Homo sapiens (Human))
University Of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM44537((2-methylbenzofuro[3,2-d]pyrimidin-4-yl)-(4-pyridy...)
Affinity DataEC50:  9.12E+4nMMore data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetProbable global transcription activator SNF2L2(Homo sapiens (Human))
University Of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM96934(6-[(4-benzylpiperazin-1-yl)methyl]-2-N-(2,3-dihydr...)
Affinity DataEC50:  9.12E+4nMMore data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetProbable global transcription activator SNF2L2(Homo sapiens (Human))
University Of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM39463(3-(2-thienyl)-1H-quinoxalin-2-one | 3-thiophen-2-y...)
Affinity DataEC50:  9.11E+4nMMore data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetProbable global transcription activator SNF2L2(Homo sapiens (Human))
University Of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM96935((2-methyl-1,3-thiazol-4-yl)methyl 3,5-dimethyl-1-p...)
Affinity DataEC50:  9.11E+4nMMore data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetProbable global transcription activator SNF2L2(Homo sapiens (Human))
University Of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM96936((5-cyclopentyl-2-phenyl-pyrazol-3-yl)amine | 5-cyc...)
Affinity DataEC50:  9.12E+4nMMore data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetProbable global transcription activator SNF2L2(Homo sapiens (Human))
University Of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM96937(MLS000055617 | N-[[1-chloranyl-2,2-di(piperidin-1-...)
Affinity DataEC50:  9.11E+4nMMore data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetProbable global transcription activator SNF2L2(Homo sapiens (Human))
University Of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM96938(4-(4-acetylphenoxy)butanoic acid [5-(4-chloropheny...)
Affinity DataEC50:  9.11E+4nMMore data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetProbable global transcription activator SNF2L2(Homo sapiens (Human))
University Of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM41389(3-(morpholin-4-ylcarbonyl)-4,5-dihydronaphtho[2,1-...)
Affinity DataEC50:  9.12E+4nMMore data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetProbable global transcription activator SNF2L2(Homo sapiens (Human))
University Of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM96939((4-amino-6,7-dimethoxy-quinazolin-2-yl)-dimethyl-a...)
Affinity DataEC50:  3.70E+4nMMore data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetProbable global transcription activator SNF2L2(Homo sapiens (Human))
University Of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM48140(MLS000063658 | N-(4-ethoxyphenyl)-1,2,5-thiadiazol...)
Affinity DataEC50:  9.12E+4nMMore data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetProbable global transcription activator SNF2L2(Homo sapiens (Human))
University Of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM96940(2-(4-methoxyphenyl)-5-(2-oxolanylmethylamino)-4-ox...)
Affinity DataEC50:  9.11E+4nMMore data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetProbable global transcription activator SNF2L2(Homo sapiens (Human))
University Of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM96941(4-[5-(4-methoxyphenyl)-1,3,4-oxadiazol-2-yl]-N,N-d...)
Affinity DataEC50:  9.12E+4nMMore data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetProbable global transcription activator SNF2L2(Homo sapiens (Human))
University Of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM96942(MLS000062930 | N-(4-benzoxyphenyl)carbamic acid me...)
Affinity DataEC50:  9.12E+4nMMore data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetProbable global transcription activator SNF2L2(Homo sapiens (Human))
University Of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM96943(4-({[1-(4-methoxyphenyl)-1H-tetrazol-5-yl]sulfonyl...)
Affinity DataEC50:  9.12E+4nMMore data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetProbable global transcription activator SNF2L2(Homo sapiens (Human))
University Of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM60218(1-(1H-benzimidazol-2-yl)-3-(4-methoxyphenyl)-1H-py...)
Affinity DataEC50:  9.12E+4nMMore data for this Ligand-Target Pair
In DepthDetails PCBioAssay
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