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Found 6 Enz. Inhib. hit(s) with Target = 'S-formylglutathione hydrolase'
TargetS-formylglutathione hydrolase(Homo sapiens)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50543567(CHEMBL4635246)
Affinity DataKd:  0.800nMAssay Description:Binding affinity to human ESD expressed in HEK293T cells assessed as dissociation constantMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetS-formylglutathione hydrolase(Homo sapiens)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50543567(CHEMBL4635246)
Affinity DataKd:  4.40nMAssay Description:Binding affinity to human ESD expressed in HEK293T cells assessed as dissociation rate constantMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetS-formylglutathione hydrolase(Sus scrofa)
Cinc

Curated by ChEMBL
LigandPNGBDBM50069665((E)-2-Acetoxy-3-{[(S)-1-((S)-2-{(S)-2-[4-(4-chloro...)
Affinity DataKi:  13nMAssay Description:Tested for inhibition of substrate hydrolysis in the presence of porcine kidney esterase at a concentration of 10 nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetS-formylglutathione hydrolase(Sus scrofa)
Cinc

Curated by ChEMBL
LigandPNGBDBM50069665((E)-2-Acetoxy-3-{[(S)-1-((S)-2-{(S)-2-[4-(4-chloro...)
Affinity DataKi:  13nMAssay Description:pA2 value towards endothelin receptor A was determined as functional ETA antagonismMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetS-formylglutathione hydrolase(Sus scrofa)
Cinc

Curated by ChEMBL
LigandPNGBDBM50069664((E)-2-Acetoxy-3-[((S)-1-{(S)-2-[(S)-2-(3-methoxyca...)
Affinity DataKi:  130nMAssay Description:Tested for inhibition of substrate hydrolysis in the presence of porcine kidney esterase at a concentration of 9 uMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetS-formylglutathione hydrolase(Sus scrofa)
Cinc

Curated by ChEMBL
LigandPNGBDBM50069664((E)-2-Acetoxy-3-[((S)-1-{(S)-2-[(S)-2-(3-methoxyca...)
Affinity DataKi:  130nMAssay Description:pA2 value towards endothelin receptor A was determined as functional ETA antagonismMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed