TargetSerine/threonine-protein kinase Sgk1(Homo sapiens (Human))
University Of Tartu
Curated by ChEMBL
University Of Tartu
Curated by ChEMBL
Affinity DataKd: 28nMAssay Description:Binding affinity to SGK1 by fluorescence anisotropy assayMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase Sgk1(Homo sapiens (Human))
University Of Tartu
Curated by ChEMBL
University Of Tartu
Curated by ChEMBL
Affinity DataKd: 331nMAssay Description:Binding affinity to recombinant full-length N-terminal His-FLAG-GST-tagged SGK1 (unknown origin) (60 to 431 residues) expressed in baculovirus infect...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase Sgk1(Homo sapiens (Human))
University Of Tartu
Curated by ChEMBL
University Of Tartu
Curated by ChEMBL
Affinity DataKd: 566nMAssay Description:Binding affinity to recombinant full-length N-terminal His-FLAG-GST-tagged SGK1 (unknown origin) (60 to 431 residues) expressed in baculovirus infect...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase Sgk1(Homo sapiens (Human))
University Of Tartu
Curated by ChEMBL
University Of Tartu
Curated by ChEMBL
Affinity DataKi: 260nMAssay Description:Inhibition of recombinant SGK after 1 hr by scintillation counter analysis in presence of gamma-[33P]ATPMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase Sgk1(Homo sapiens (Human))
University Of Tartu
Curated by ChEMBL
University Of Tartu
Curated by ChEMBL
TargetSerine/threonine-protein kinase Sgk1(Homo sapiens (Human))
University Of Tartu
Curated by ChEMBL
University Of Tartu
Curated by ChEMBL
Affinity DataKi: 600nMAssay Description:Inhibition of human N-terminal His6-tagged N-truncated human SGK1 harboring S422D mutant expressed in Sf21 cells using Sgktide-peptide as substrate i...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase Sgk1(Homo sapiens (Human))
University Of Tartu
Curated by ChEMBL
University Of Tartu
Curated by ChEMBL
Affinity DataKi: >1.00E+3nMAssay Description:Inhibition of SGK1More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase Sgk1(Homo sapiens (Human))
University Of Tartu
Curated by ChEMBL
University Of Tartu
Curated by ChEMBL
Affinity DataKi: >2.00E+3nMAssay Description:Inhibition of SGK1 (unknown origin)More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase Sgk1(Homo sapiens (Human))
University Of Tartu
Curated by ChEMBL
University Of Tartu
Curated by ChEMBL
Affinity DataKi: >2.00E+3nMAssay Description:Inhibition of SGK1 (unknown origin)More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase Sgk1(Homo sapiens (Human))
University Of Tartu
Curated by ChEMBL
University Of Tartu
Curated by ChEMBL
Affinity DataKi: >2.00E+3nMAssay Description:Inhibition of SGK (unknown origin)More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase Sgk1(Homo sapiens (Human))
University Of Tartu
Curated by ChEMBL
University Of Tartu
Curated by ChEMBL
Affinity DataKi: >5.00E+3nMAssay Description:Inhibition of SGK (unknown origin)More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase Sgk1(Homo sapiens (Human))
University Of Tartu
Curated by ChEMBL
University Of Tartu
Curated by ChEMBL
TargetSerine/threonine-protein kinase Sgk1(Homo sapiens (Human))
University Of Tartu
Curated by ChEMBL
University Of Tartu
Curated by ChEMBL
Affinity DataIC50: 1.10E+5nMAssay Description:Selected compounds were screened against a panel of mammalian kinases. Compounds were supplied in DMSO and screened in duplicates at 100 uM concentr...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase Sgk1(Homo sapiens (Human))
University Of Tartu
Curated by ChEMBL
University Of Tartu
Curated by ChEMBL
Affinity DataIC50: 3nMAssay Description:The compounds were tested for serum and glucocorticoid-regulated kinase 1 (SGK-1) inhibitory activity in a substrate phosphorylation assay designed t...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase Sgk1(Homo sapiens (Human))
University Of Tartu
Curated by ChEMBL
University Of Tartu
Curated by ChEMBL
Affinity DataIC50: 439nMAssay Description:The compounds were tested for serum and glucocorticoid-regulated kinase 1 (SGK-1) inhibitory activity in a substrate phosphorylation assay designed t...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase Sgk1(Homo sapiens (Human))
University Of Tartu
Curated by ChEMBL
University Of Tartu
Curated by ChEMBL
Affinity DataIC50: 496nMAssay Description:The compounds were tested for serum and glucocorticoid-regulated kinase 1 (SGK-1) inhibitory activity in a substrate phosphorylation assay designed t...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase Sgk1(Homo sapiens (Human))
University Of Tartu
Curated by ChEMBL
University Of Tartu
Curated by ChEMBL
Affinity DataIC50: 419nMAssay Description:The compounds were tested for serum and glucocorticoid-regulated kinase 1 (SGK-1) inhibitory activity in a substrate phosphorylation assay designed t...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase Sgk1(Homo sapiens (Human))
University Of Tartu
Curated by ChEMBL
University Of Tartu
Curated by ChEMBL
Affinity DataIC50: 5nMAssay Description:The compounds were tested for serum and glucocorticoid-regulated kinase 1 (SGK-1) inhibitory activity in a substrate phosphorylation assay designed t...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase Sgk1(Homo sapiens (Human))
University Of Tartu
Curated by ChEMBL
University Of Tartu
Curated by ChEMBL
Affinity DataIC50: 2nMAssay Description:The compounds were tested for serum and glucocorticoid-regulated kinase 1 (SGK-1) inhibitory activity in a substrate phosphorylation assay designed t...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase Sgk1(Homo sapiens (Human))
University Of Tartu
Curated by ChEMBL
University Of Tartu
Curated by ChEMBL
Affinity DataIC50: 2nMAssay Description:The compounds were tested for serum and glucocorticoid-regulated kinase 1 (SGK-1) inhibitory activity in a substrate phosphorylation assay designed t...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase Sgk1(Homo sapiens (Human))
University Of Tartu
Curated by ChEMBL
University Of Tartu
Curated by ChEMBL
Affinity DataIC50: 196nMAssay Description:The compounds were tested for serum and glucocorticoid-regulated kinase 1 (SGK-1) inhibitory activity in a substrate phosphorylation assay designed t...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase Sgk1(Homo sapiens (Human))
University Of Tartu
Curated by ChEMBL
University Of Tartu
Curated by ChEMBL
Affinity DataIC50: 3nMAssay Description:The compounds were tested for serum and glucocorticoid-regulated kinase 1 (SGK-1) inhibitory activity in a substrate phosphorylation assay designed t...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase Sgk1(Homo sapiens (Human))
University Of Tartu
Curated by ChEMBL
University Of Tartu
Curated by ChEMBL
Affinity DataIC50: 13nMAssay Description:The compounds were tested for serum and glucocorticoid-regulated kinase 1 (SGK-1) inhibitory activity in a substrate phosphorylation assay designed t...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase Sgk1(Homo sapiens (Human))
University Of Tartu
Curated by ChEMBL
University Of Tartu
Curated by ChEMBL
Affinity DataIC50: 2nMAssay Description:The compounds were tested for serum and glucocorticoid-regulated kinase 1 (SGK-1) inhibitory activity in a substrate phosphorylation assay designed t...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase Sgk1(Homo sapiens (Human))
University Of Tartu
Curated by ChEMBL
University Of Tartu
Curated by ChEMBL
Affinity DataIC50: 4nMAssay Description:The compounds were tested for serum and glucocorticoid-regulated kinase 1 (SGK-1) inhibitory activity in a substrate phosphorylation assay designed t...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase Sgk1(Homo sapiens (Human))
University Of Tartu
Curated by ChEMBL
University Of Tartu
Curated by ChEMBL
Affinity DataIC50: 3nMAssay Description:The compounds were tested for serum and glucocorticoid-regulated kinase 1 (SGK-1) inhibitory activity in a substrate phosphorylation assay designed t...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase Sgk1(Homo sapiens (Human))
University Of Tartu
Curated by ChEMBL
University Of Tartu
Curated by ChEMBL
Affinity DataIC50: 3nMAssay Description:The compounds were tested for serum and glucocorticoid-regulated kinase 1 (SGK-1) inhibitory activity in a substrate phosphorylation assay designed t...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase Sgk1(Homo sapiens (Human))
University Of Tartu
Curated by ChEMBL
University Of Tartu
Curated by ChEMBL
Affinity DataIC50: 2nMAssay Description:The compounds were tested for serum and glucocorticoid-regulated kinase 1 (SGK-1) inhibitory activity in a substrate phosphorylation assay designed t...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase Sgk1(Homo sapiens (Human))
University Of Tartu
Curated by ChEMBL
University Of Tartu
Curated by ChEMBL
Affinity DataIC50: 2nMAssay Description:The compounds were tested for serum and glucocorticoid-regulated kinase 1 (SGK-1) inhibitory activity in a substrate phosphorylation assay designed t...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase Sgk1(Homo sapiens (Human))
University Of Tartu
Curated by ChEMBL
University Of Tartu
Curated by ChEMBL
Affinity DataIC50: 1nMAssay Description:The compounds were tested for serum and glucocorticoid-regulated kinase 1 (SGK-1) inhibitory activity in a substrate phosphorylation assay designed t...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase Sgk1(Homo sapiens (Human))
University Of Tartu
Curated by ChEMBL
University Of Tartu
Curated by ChEMBL
Affinity DataIC50: 413nMAssay Description:The compounds were tested for serum and glucocorticoid-regulated kinase 1 (SGK-1) inhibitory activity in a substrate phosphorylation assay designed t...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase Sgk1(Homo sapiens (Human))
University Of Tartu
Curated by ChEMBL
University Of Tartu
Curated by ChEMBL
Affinity DataIC50: 1.05E+3nMAssay Description:The compounds were tested for serum and glucocorticoid-regulated kinase 1 (SGK-1) inhibitory activity in a substrate phosphorylation assay designed t...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase Sgk1(Homo sapiens (Human))
University Of Tartu
Curated by ChEMBL
University Of Tartu
Curated by ChEMBL
Affinity DataIC50: 47nMAssay Description:The compounds were tested for serum and glucocorticoid-regulated kinase 1 (SGK-1) inhibitory activity in a substrate phosphorylation assay designed t...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase Sgk1(Homo sapiens (Human))
University Of Tartu
Curated by ChEMBL
University Of Tartu
Curated by ChEMBL
Affinity DataIC50: 2nMAssay Description:The compounds were tested for serum and glucocorticoid-regulated kinase 1 (SGK-1) inhibitory activity in a substrate phosphorylation assay designed t...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase Sgk1(Homo sapiens (Human))
University Of Tartu
Curated by ChEMBL
University Of Tartu
Curated by ChEMBL
Affinity DataIC50: 15nMAssay Description:The compounds were tested for serum and glucocorticoid-regulated kinase 1 (SGK-1) inhibitory activity in a substrate phosphorylation assay designed t...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase Sgk1(Homo sapiens (Human))
University Of Tartu
Curated by ChEMBL
University Of Tartu
Curated by ChEMBL
Affinity DataIC50: 22nMAssay Description:The compounds were tested for serum and glucocorticoid-regulated kinase 1 (SGK-1) inhibitory activity in a substrate phosphorylation assay designed t...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase Sgk1(Homo sapiens (Human))
University Of Tartu
Curated by ChEMBL
University Of Tartu
Curated by ChEMBL
Affinity DataIC50: 31nMAssay Description:The compounds were tested for serum and glucocorticoid-regulated kinase 1 (SGK-1) inhibitory activity in a substrate phosphorylation assay designed t...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase Sgk1(Homo sapiens (Human))
University Of Tartu
Curated by ChEMBL
University Of Tartu
Curated by ChEMBL
Affinity DataIC50: 18nMAssay Description:The compounds were tested for serum and glucocorticoid-regulated kinase 1 (SGK-1) inhibitory activity in a substrate phosphorylation assay designed t...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase Sgk1(Homo sapiens (Human))
University Of Tartu
Curated by ChEMBL
University Of Tartu
Curated by ChEMBL
Affinity DataIC50: 21nMAssay Description:The compounds were tested for serum and glucocorticoid-regulated kinase 1 (SGK-1) inhibitory activity in a substrate phosphorylation assay designed t...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase Sgk1(Homo sapiens (Human))
University Of Tartu
Curated by ChEMBL
University Of Tartu
Curated by ChEMBL
Affinity DataIC50: 14nMAssay Description:The compounds were tested for serum and glucocorticoid-regulated kinase 1 (SGK-1) inhibitory activity in a substrate phosphorylation assay designed t...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase Sgk1(Homo sapiens (Human))
University Of Tartu
Curated by ChEMBL
University Of Tartu
Curated by ChEMBL
Affinity DataIC50: 3nMpH: 7.4 T: 2°CAssay Description:The enzyme reaction was carried out in a buffer containing 25 mM
Tris-HCl (pH 7.4), 5 mM MgCl2, 2 mM MnCl2, 2 mM DTT, and 0.03% bovine
serum albumi...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase Sgk1(Homo sapiens (Human))
University Of Tartu
Curated by ChEMBL
University Of Tartu
Curated by ChEMBL
Affinity DataIC50: 439nMpH: 7.4 T: 2°CAssay Description:The enzyme reaction was carried out in a buffer containing 25 mM
Tris-HCl (pH 7.4), 5 mM MgCl2, 2 mM MnCl2, 2 mM DTT, and 0.03% bovine
serum albumi...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase Sgk1(Homo sapiens (Human))
University Of Tartu
Curated by ChEMBL
University Of Tartu
Curated by ChEMBL
Affinity DataIC50: 496nMpH: 7.4 T: 2°CAssay Description:The enzyme reaction was carried out in a buffer containing 25 mM
Tris-HCl (pH 7.4), 5 mM MgCl2, 2 mM MnCl2, 2 mM DTT, and 0.03% bovine
serum albumi...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase Sgk1(Homo sapiens (Human))
University Of Tartu
Curated by ChEMBL
University Of Tartu
Curated by ChEMBL
Affinity DataIC50: 419nMpH: 7.4 T: 2°CAssay Description:The enzyme reaction was carried out in a buffer containing 25 mM
Tris-HCl (pH 7.4), 5 mM MgCl2, 2 mM MnCl2, 2 mM DTT, and 0.03% bovine
serum albumi...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase Sgk1(Homo sapiens (Human))
University Of Tartu
Curated by ChEMBL
University Of Tartu
Curated by ChEMBL
Affinity DataIC50: 5nMpH: 7.4 T: 2°CAssay Description:The enzyme reaction was carried out in a buffer containing 25 mM
Tris-HCl (pH 7.4), 5 mM MgCl2, 2 mM MnCl2, 2 mM DTT, and 0.03% bovine
serum albumi...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase Sgk1(Homo sapiens (Human))
University Of Tartu
Curated by ChEMBL
University Of Tartu
Curated by ChEMBL
Affinity DataIC50: 2nMpH: 7.4 T: 2°CAssay Description:The enzyme reaction was carried out in a buffer containing 25 mM
Tris-HCl (pH 7.4), 5 mM MgCl2, 2 mM MnCl2, 2 mM DTT, and 0.03% bovine
serum albumi...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase Sgk1(Homo sapiens (Human))
University Of Tartu
Curated by ChEMBL
University Of Tartu
Curated by ChEMBL
Affinity DataIC50: 2nMpH: 7.4 T: 2°CAssay Description:The enzyme reaction was carried out in a buffer containing 25 mM
Tris-HCl (pH 7.4), 5 mM MgCl2, 2 mM MnCl2, 2 mM DTT, and 0.03% bovine
serum albumi...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase Sgk1(Homo sapiens (Human))
University Of Tartu
Curated by ChEMBL
University Of Tartu
Curated by ChEMBL
Affinity DataIC50: 196nMpH: 7.4 T: 2°CAssay Description:The enzyme reaction was carried out in a buffer containing 25 mM
Tris-HCl (pH 7.4), 5 mM MgCl2, 2 mM MnCl2, 2 mM DTT, and 0.03% bovine
serum albumi...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase Sgk1(Homo sapiens (Human))
University Of Tartu
Curated by ChEMBL
University Of Tartu
Curated by ChEMBL
Affinity DataIC50: 3nMpH: 7.4 T: 2°CAssay Description:The enzyme reaction was carried out in a buffer containing 25 mM
Tris-HCl (pH 7.4), 5 mM MgCl2, 2 mM MnCl2, 2 mM DTT, and 0.03% bovine
serum albumi...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase Sgk1(Homo sapiens (Human))
University Of Tartu
Curated by ChEMBL
University Of Tartu
Curated by ChEMBL
Affinity DataIC50: 13nMpH: 7.4 T: 2°CAssay Description:The enzyme reaction was carried out in a buffer containing 25 mM
Tris-HCl (pH 7.4), 5 mM MgCl2, 2 mM MnCl2, 2 mM DTT, and 0.03% bovine
serum albumi...More data for this Ligand-Target Pair