Compile Data Set for Download or QSAR
maximum 50k data
Found 1001 Enz. Inhib. hit(s) with Target = 'Similar to alpha-tubulin isoform 1'
TargetSimilar to alpha-tubulin isoform 1(Bos taurus)
Minia University

Curated by ChEMBL
LigandPNGBDBM50005480((-)-combretastatin | (Z)-3'-hydroxy-3,4,4',5-tetra...)
Affinity DataKd:  310nMAssay Description:Inhibition of [3H] colchicine binding to bovine brain tubulin incubated for 30 mins by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSimilar to alpha-tubulin isoform 1(Bos taurus)
Minia University

Curated by ChEMBL
LigandPNGBDBM50504214(CHEMBL4530425)
Affinity DataKd:  320nMAssay Description:Inhibition of [3H] colchicine binding to bovine brain tubulin incubated for 30 mins by scintillation proximity assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSimilar to alpha-tubulin isoform 1(Bos taurus)
Minia University

Curated by ChEMBL
LigandPNGBDBM50504215(CHEMBL4463939)
Affinity DataKd:  540nMAssay Description:Inhibition of [3H] colchicine binding to bovine brain tubulin incubated for 30 mins by scintillation proximity assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSimilar to alpha-tubulin isoform 1(Bos taurus)
Minia University

Curated by ChEMBL
LigandPNGBDBM50069693(CHEMBL3400854)
Affinity DataKd:  2.10E+4nMAssay Description:Binding affinity to bovine brain tubulin assessed as reduction in tubulin intrinsic tryptophan fluorescence intensity incubated for 45 mins by spectr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSimilar to alpha-tubulin isoform 1(Bos taurus)
Minia University

Curated by ChEMBL
LigandPNGBDBM50069694(CHEMBL3400853)
Affinity DataKd:  2.60E+4nMAssay Description:Binding affinity to bovine brain tubulin assessed as reduction in tubulin intrinsic tryptophan fluorescence intensity incubated for 45 mins by spectr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSimilar to alpha-tubulin isoform 1(Bos taurus)
Minia University

Curated by ChEMBL
LigandPNGBDBM50069695(CHEMBL3400852)
Affinity DataKd:  4.40E+4nMAssay Description:Binding affinity to bovine brain tubulin assessed as reduction in tubulin intrinsic tryptophan fluorescence intensity incubated for 45 mins by spectr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSimilar to alpha-tubulin isoform 1(Bos taurus)
Minia University

Curated by ChEMBL
LigandPNGBDBM50069696(CHEMBL3400851)
Affinity DataKd:  5.50E+4nMAssay Description:Binding affinity to bovine brain tubulin assessed as reduction in tubulin intrinsic tryptophan fluorescence intensity incubated for 45 mins by spectr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSimilar to alpha-tubulin isoform 1(Bos taurus)
Minia University

Curated by ChEMBL
LigandPNGBDBM50005480((-)-combretastatin | (Z)-3'-hydroxy-3,4,4',5-tetra...)
Affinity DataKi:  140nMAssay Description:Inhibition of [3H] colchicine binding to bovine brain tubulin incubated for 30 mins by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSimilar to alpha-tubulin isoform 1(Bos taurus)
Minia University

Curated by ChEMBL
LigandPNGBDBM50504214(CHEMBL4530425)
Affinity DataKi:  150nMAssay Description:Inhibition of [3H] colchicine binding to bovine brain tubulin incubated for 30 mins by scintillation proximity assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSimilar to alpha-tubulin isoform 1(Bos taurus)
Minia University

Curated by ChEMBL
LigandPNGBDBM50504215(CHEMBL4463939)
Affinity DataKi:  260nMAssay Description:Inhibition of [3H] colchicine binding to bovine brain tubulin incubated for 30 mins by scintillation proximity assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSimilar to alpha-tubulin isoform 1/Tubulin beta-2B chain(Bos taurus)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50127060(5-(2,5-Dimethoxy-phenylethynyl)-N-hexyl-2-methoxy-...)
Affinity DataIC50: >4.00E+4nMAssay Description:Inhibition of tubulin polymerization was determined at 1.2 mg/mL concentrationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSimilar to alpha-tubulin isoform 1/Tubulin beta-2B chain(Bos taurus)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50127061(5-(2,5-Dihydroxy-phenylethynyl)-2-hydroxy-N-phenet...)
Affinity DataIC50:  3.70E+3nMAssay Description:Inhibition of tubulin polymerization was determined at 1.2 mg/mL concentrationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSimilar to alpha-tubulin isoform 1/Tubulin beta-2B chain(Bos taurus)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50127062(5-(2,5-Dimethoxy-phenylethynyl)-2-methoxy-benzoic ...)
Affinity DataIC50: >4.00E+4nMAssay Description:Inhibition of tubulin polymerization was determined at 1.2 mg/mL concentrationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSimilar to alpha-tubulin isoform 1/Tubulin beta-2B chain(Bos taurus)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50127064(5-[2-(2,5-Dihydroxy-phenyl)-vinyl]-N-hexyl-2-hydro...)
Affinity DataIC50:  4.20E+3nMAssay Description:Inhibition of tubulin polymerization was determined at 1.2 mg/mL concentrationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSimilar to alpha-tubulin isoform 1/Tubulin beta-2B chain(Bos taurus)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50127063(5-[2-(2,5-Dihydroxy-phenyl)-vinyl]-N-hexyl-2-hydro...)
Affinity DataIC50:  5.00E+3nMAssay Description:Inhibition of tubulin polymerization was determined at 1.2 mg/mL concentrationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSimilar to alpha-tubulin isoform 1/Tubulin beta-2B chain(Bos taurus)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50127065(5-[2-(2,5-Dihydroxy-phenyl)-ethyl]-N-hexyl-2-hydro...)
Affinity DataIC50:  6.20E+3nMAssay Description:Inhibition of tubulin polymerization was determined at 1.2 mg/mL concentrationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSimilar to alpha-tubulin isoform 1/Tubulin beta-2B chain(Bos taurus)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50127066(5-[2-(2,5-Dimethoxy-phenyl)-ethyl]-N-[2-(4-fluoro-...)
Affinity DataIC50:  1.40E+3nMAssay Description:Inhibition of tubulin polymerization was determined at 1.2 mg/mL concentrationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSimilar to alpha-tubulin isoform 1/Tubulin beta-2B chain(Bos taurus)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50005480((-)-combretastatin | (Z)-3'-hydroxy-3,4,4',5-tetra...)
Affinity DataIC50:  1.90E+3nMAssay Description:Inhibition of tubulin polymerization was determined at 1.2 mg/mL concentrationMore data for this Ligand-Target Pair
TargetSimilar to alpha-tubulin isoform 1/Tubulin beta-2B chain(Bos taurus)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50035218(CHEMBL61 | PODOFILOX | Podophyllinic acid lactone ...)
Affinity DataIC50:  2.10E+3nMAssay Description:Inhibition of tubulin polymerization was determined at 1.2 mg/mL concentrationMore data for this Ligand-Target Pair
TargetSimilar to alpha-tubulin isoform 1/Tubulin beta-2B chain(Bos taurus)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50127067(5-(2,5-Dimethoxy-phenylethynyl)-2-methoxy-benzoic ...)
Affinity DataIC50: >4.00E+4nMAssay Description:Inhibition of tubulin polymerization was determined at 1.2 mg/mL concentrationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSimilar to alpha-tubulin isoform 1/Tubulin beta-2B chain(Bos taurus)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50127068(5-[2-(2,5-Dihydroxy-phenyl)-vinyl]-2-hydroxy-N-phe...)
Affinity DataIC50:  4.00E+3nMAssay Description:Inhibition of tubulin polymerization was determined at 1.2 mg/mL concentrationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSimilar to alpha-tubulin isoform 1/Tubulin beta-2B chain(Bos taurus)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50009568((Thiocolchicine)N-(1,2,3-Trimethoxy-10-methylsulfa...)
Affinity DataIC50:  1.40E+3nMAssay Description:Inhibition of tubulin polymerization was determined at 1.2 mg/mL concentrationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSimilar to alpha-tubulin isoform 1/Tubulin beta-2B chain(Bos taurus)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50127069(5-[2-(2,5-Dimethoxy-phenyl)-vinyl]-N-[2-(4-fluoro-...)
Affinity DataIC50: >4.00E+4nMAssay Description:Inhibition of tubulin polymerization was determined at 1.2 mg/mL concentrationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSimilar to alpha-tubulin isoform 1/Tubulin beta-2B chain(Bos taurus)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50127071(5-[2-(2,5-Dihydroxy-phenyl)-ethyl]-N-[2-(4-fluoro-...)
Affinity DataIC50:  9.70E+3nMAssay Description:Inhibition of tubulin polymerization was determined at 1.2 mg/mL concentrationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSimilar to alpha-tubulin isoform 1/Tubulin beta-2B chain(Bos taurus)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50127070(5-[2-(2,5-Dihydroxy-phenyl)-vinyl]-N-[2-(4-fluoro-...)
Affinity DataIC50:  2.90E+3nMAssay Description:Inhibition of tubulin polymerization was determined at 1.2 mg/mL concentrationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSimilar to alpha-tubulin isoform 1/Tubulin beta-2B chain(Bos taurus)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50127072(5-(2,5-Dimethoxy-phenylethynyl)-N-[2-(4-fluoro-phe...)
Affinity DataIC50: >4.00E+4nMAssay Description:Inhibition of tubulin polymerization was determined at 1.2 mg/mL concentrationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSimilar to alpha-tubulin isoform 1/Tubulin beta-2B chain(Bos taurus)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50127073(5-[2-(2,5-Dimethoxy-phenyl)-acetyl]-N-[2-(4-fluoro...)
Affinity DataIC50:  1.40E+3nMAssay Description:Inhibition of tubulin polymerization was determined at 1.2 mg/mL concentrationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSimilar to alpha-tubulin isoform 1/Tubulin beta-2B chain(Bos taurus)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50102416(5-(2,5-Dihydroxy-benzylamino)-N-[2-(4-fluoro-pheny...)
Affinity DataIC50:  6.40E+3nMAssay Description:Inhibition of tubulin polymerization was determined at 1.2 mg/mL concentrationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSimilar to alpha-tubulin isoform 1/Tubulin beta-2B chain(Bos taurus)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50127074(5-[2-(2,5-Dimethoxy-phenyl)-vinyl]-2-methoxy-N-phe...)
Affinity DataIC50: >4.00E+4nMAssay Description:Inhibition of tubulin polymerization was determined at 1.2 mg/mL concentrationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSimilar to alpha-tubulin isoform 1/Tubulin beta-2B chain(Bos taurus)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50127075(5-[2-(2,5-Dimethoxy-phenyl)-vinyl]-2-methoxy-benzo...)
Affinity DataIC50: >4.00E+4nMAssay Description:Inhibition of tubulin polymerization was determined at 1.2 mg/mL concentrationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSimilar to alpha-tubulin isoform 1/Tubulin beta-2B chain(Bos taurus)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50127076(5-[2-(2,5-Dihydroxy-phenyl)-ethyl]-2-hydroxy-N-phe...)
Affinity DataIC50:  5.50E+3nMAssay Description:Inhibition of tubulin polymerization was determined at 1.2 mg/mL concentrationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSimilar to alpha-tubulin isoform 1/Tubulin beta-2B chain(Bos taurus)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50127078(5-[2-(2,5-Dihydroxy-phenyl)-vinyl]-2-hydroxy-N-phe...)
Affinity DataIC50:  5.40E+3nMAssay Description:Inhibition of tubulin polymerization was determined at 1.2 mg/mL concentrationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSimilar to alpha-tubulin isoform 1/Tubulin beta-2B chain(Bos taurus)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50127077(5-[2-(2,5-Dihydroxy-phenyl)-vinyl]-N-[2-(4-fluoro-...)
Affinity DataIC50:  4.20E+3nMAssay Description:Inhibition of tubulin polymerization was determined at 1.2 mg/mL concentrationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSimilar to alpha-tubulin isoform 1/Tubulin beta-2B chain(Bos taurus)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50127079(5-(2,5-Dimethoxy-phenylethynyl)-2-methoxy-N-phenet...)
Affinity DataIC50: >4.00E+4nMAssay Description:Inhibition of tubulin polymerization was determined at 1.2 mg/mL concentrationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSimilar to alpha-tubulin isoform 1/Tubulin beta-2B chain(Bos taurus)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50127080(5-[2-(2,5-Dimethoxy-phenyl)-vinyl]-N-hexyl-2-metho...)
Affinity DataIC50: >4.00E+4nMAssay Description:Inhibition of tubulin polymerization was determined at 1.2 mg/mL concentrationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSimilar to alpha-tubulin isoform 1/Tubulin beta-2B chain(Bos taurus)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50005480((-)-combretastatin | (Z)-3'-hydroxy-3,4,4',5-tetra...)
Affinity DataIC50:  900nMAssay Description:Inhibition of bovine brain tubulin polymerizationMore data for this Ligand-Target Pair
TargetSimilar to alpha-tubulin isoform 1(Bos taurus)
Minia University

Curated by ChEMBL
LigandPNGBDBM50042033(CHEMBL3360145)
Affinity DataIC50:  3.00E+3nMAssay Description:Inhibition of bovine brain tubulin polymerizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSimilar to alpha-tubulin isoform 1(Bos taurus)
Minia University

Curated by ChEMBL
LigandPNGBDBM50046751(CHEMBL3309646)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of bovine brain tubulin polymerization measured for 1 hr at 1 min intervals by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSimilar to alpha-tubulin isoform 1(Bos taurus)
Minia University

Curated by ChEMBL
LigandPNGBDBM50046752(CHEMBL3309648)
Affinity DataIC50:  830nMAssay Description:Inhibition of bovine brain tubulin polymerization measured for 1 hr at 1 min intervals by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSimilar to alpha-tubulin isoform 1(Bos taurus)
Minia University

Curated by ChEMBL
LigandPNGBDBM50046812(CHEMBL3309649)
Affinity DataIC50:  920nMAssay Description:Inhibition of bovine brain tubulin polymerization measured for 1 hr at 1 min intervals by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSimilar to alpha-tubulin isoform 1(Bos taurus)
Minia University

Curated by ChEMBL
LigandPNGBDBM50035218(CHEMBL61 | PODOFILOX | Podophyllinic acid lactone ...)
Affinity DataIC50:  810nMAssay Description:Inhibition of bovine brain tubulin polymerization measured for 1 hr at 1 min intervals by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSimilar to alpha-tubulin isoform 1(Bos taurus)
Minia University

Curated by ChEMBL
LigandPNGBDBM50045458(CHEMBL3309810)
Affinity DataIC50:  3.14E+3nMAssay Description:Inhibition of bovine brain tubulin polymerization after 20 mins by turbidimetric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSimilar to alpha-tubulin isoform 1(Bos taurus)
Minia University

Curated by ChEMBL
LigandPNGBDBM50045459(CHEMBL3309811)
Affinity DataIC50:  7.78E+3nMAssay Description:Inhibition of bovine brain tubulin polymerization after 20 mins by turbidimetric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSimilar to alpha-tubulin isoform 1(Bos taurus)
Minia University

Curated by ChEMBL
LigandPNGBDBM50045460(CHEMBL3309812)
Affinity DataIC50:  7.39E+3nMAssay Description:Inhibition of bovine brain tubulin polymerization after 20 mins by turbidimetric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSimilar to alpha-tubulin isoform 1(Bos taurus)
Minia University

Curated by ChEMBL
LigandPNGBDBM50045461(CHEMBL3309813)
Affinity DataIC50:  5.46E+3nMAssay Description:Inhibition of bovine brain tubulin polymerization after 20 mins by turbidimetric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSimilar to alpha-tubulin isoform 1(Bos taurus)
Minia University

Curated by ChEMBL
LigandPNGBDBM50045462(CHEMBL3309814)
Affinity DataIC50:  5.28E+3nMAssay Description:Inhibition of bovine brain tubulin polymerization after 20 mins by turbidimetric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSimilar to alpha-tubulin isoform 1(Bos taurus)
Minia University

Curated by ChEMBL
LigandPNGBDBM50045463(CHEMBL3309815)
Affinity DataIC50:  1.72E+3nMAssay Description:Inhibition of bovine brain tubulin polymerization after 20 mins by turbidimetric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSimilar to alpha-tubulin isoform 1(Bos taurus)
Minia University

Curated by ChEMBL
LigandPNGBDBM50045464(CHEMBL3309816)
Affinity DataIC50:  3.08E+3nMAssay Description:Inhibition of bovine brain tubulin polymerization after 20 mins by turbidimetric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSimilar to alpha-tubulin isoform 1(Bos taurus)
Minia University

Curated by ChEMBL
LigandPNGBDBM50045465(CHEMBL3309817)
Affinity DataIC50:  1.86E+3nMAssay Description:Inhibition of bovine brain tubulin polymerization after 20 mins by turbidimetric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSimilar to alpha-tubulin isoform 1(Bos taurus)
Minia University

Curated by ChEMBL
LigandPNGBDBM50045466(CHEMBL3310099)
Affinity DataIC50:  5.89E+3nMAssay Description:Inhibition of bovine brain tubulin polymerization after 20 mins by turbidimetric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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