Compile Data Set for Download or QSAR
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Found 3 Enz. Inhib. hit(s) with Target = 'Thiopurine S-methyltransferase'
TargetThiopurine S-methyltransferase(Homo sapiens (Human))
Janssen Research And Development

Curated by ChEMBL
LigandPNGBDBM50378739(SINEFUNGIN | jm2c00120, Sinefungin)
Affinity DataKd:  1.00E+4nMAssay Description:Binding affinity to thiopurine methyltransferase (unknown origin) by NMR analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThiopurine S-methyltransferase(Homo sapiens (Human))
Janssen Research And Development

Curated by ChEMBL
LigandPNGBDBM50530712(CHEMBL4591248)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of human TPMT expressed in Escherichia coli assessed as reduction in SAH level using 6-mercaptopurine as substrate in presence of SAM incu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetThiopurine S-methyltransferase(Homo sapiens (Human))
Janssen Research And Development

Curated by ChEMBL
LigandPNGBDBM50530712(CHEMBL4591248)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of human TPMT expressed in Escherichia coli assessed as reduction in SAH level using 6-mercaptopurine as substrate in presence of SAM incu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed