TargetUracil nucleotide/cysteinyl leukotriene receptor(Homo sapiens (Human))
Northwest University
Curated by ChEMBL
Northwest University
Curated by ChEMBL
Affinity DataKd: 13nMAssay Description:Binding affinity to immobilized Halo tag-fused CysLT receptor (unknown origin) expressed in Escherichia coli BL21 (DE3) assessed as dissociation rate...More data for this Ligand-Target Pair
TargetUracil nucleotide/cysteinyl leukotriene receptor(Homo sapiens (Human))
Northwest University
Curated by ChEMBL
Northwest University
Curated by ChEMBL
Affinity DataKd: 17nMAssay Description:Binding affinity to immobilized Halo tag-fused CysLT receptor (unknown origin) expressed in Escherichia coli BL21 (DE3) assessed as dissociation rate...More data for this Ligand-Target Pair
TargetUracil nucleotide/cysteinyl leukotriene receptor(Homo sapiens (Human))
Northwest University
Curated by ChEMBL
Northwest University
Curated by ChEMBL
Affinity DataKd: 1.26E+3nMAssay Description:Binding affinity to human GPR17 expressed in CHO-K1 cell membranes after 60 mins by saturation curve studyMore data for this Ligand-Target Pair
TargetUracil nucleotide/cysteinyl leukotriene receptor(Homo sapiens (Human))
Northwest University
Curated by ChEMBL
Northwest University
Curated by ChEMBL
Affinity DataKi: 1.21E+3nMAssay Description:Displacement of [3H]PSB-12150 from human GPR17 expressed in CHO-K1 cell membranes after 60 mins by homologous competition binding assay in presence o...More data for this Ligand-Target Pair
TargetUracil nucleotide/cysteinyl leukotriene receptor(Homo sapiens (Human))
Northwest University
Curated by ChEMBL
Northwest University
Curated by ChEMBL
Affinity DataKi: 1.50E+3nMAssay Description:Displacement of [3H]PSB-12150 from human GPR17 expressed in CHO cell membranes after 60 mins by liquid scintillation countingMore data for this Ligand-Target Pair
TargetUracil nucleotide/cysteinyl leukotriene receptor(Homo sapiens (Human))
Northwest University
Curated by ChEMBL
Northwest University
Curated by ChEMBL
Affinity DataKi: 1.63E+3nMAssay Description:Displacement of [3H]PSB-12150 from human GPR17 expressed in CHO-K1 cell membranes after 60 mins by heterologous competition binding assayMore data for this Ligand-Target Pair
TargetUracil nucleotide/cysteinyl leukotriene receptor(Homo sapiens (Human))
Northwest University
Curated by ChEMBL
Northwest University
Curated by ChEMBL
Affinity DataKi: 2.32E+3nMAssay Description:Displacement of [3H]PSB-12150 from human GPR17 expressed in CHO-K1 cell membranes after 60 mins by competition binding assayMore data for this Ligand-Target Pair
TargetUracil nucleotide/cysteinyl leukotriene receptor(Homo sapiens (Human))
Northwest University
Curated by ChEMBL
Northwest University
Curated by ChEMBL
Affinity DataKi: 2.45E+3nMAssay Description:Displacement of [3H]PSB-12150 from human GPR17 expressed in CHO cell membranes after 60 mins by liquid scintillation countingMore data for this Ligand-Target Pair
TargetUracil nucleotide/cysteinyl leukotriene receptor(Homo sapiens (Human))
Northwest University
Curated by ChEMBL
Northwest University
Curated by ChEMBL
Affinity DataKi: 4.06E+3nMAssay Description:Displacement of [3H]PSB-12150 from human GPR17 expressed in CHO-K1 cell membranes after 60 mins by heterologous competition binding assayMore data for this Ligand-Target Pair
TargetUracil nucleotide/cysteinyl leukotriene receptor(Homo sapiens (Human))
Northwest University
Curated by ChEMBL
Northwest University
Curated by ChEMBL
Affinity DataKi: 6.54E+3nMAssay Description:Displacement of [3H]PSB-12150 from human GPR17 expressed in CHO-K1 cell membranes after 60 mins by heterologous competition binding assayMore data for this Ligand-Target Pair
TargetUracil nucleotide/cysteinyl leukotriene receptor(Homo sapiens (Human))
Northwest University
Curated by ChEMBL
Northwest University
Curated by ChEMBL
Affinity DataKi: 1.31E+4nMAssay Description:Displacement of [3H]PSB-12150 from human GPR17 expressed in CHO cell membranes after 60 mins by liquid scintillation countingMore data for this Ligand-Target Pair
TargetUracil nucleotide/cysteinyl leukotriene receptor(Homo sapiens (Human))
Northwest University
Curated by ChEMBL
Northwest University
Curated by ChEMBL
Affinity DataEC50: 1.14E+3nMAssay Description:Agonist activity at human GPR17 expressed in human 1321N1 cells assessed as induction of [35S]GTPgammaS binding after 30 mins by rapid filtration ass...More data for this Ligand-Target Pair
TargetUracil nucleotide/cysteinyl leukotriene receptor(Homo sapiens (Human))
Northwest University
Curated by ChEMBL
Northwest University
Curated by ChEMBL
Affinity DataEC50: 945nMAssay Description:Agonist activity at human GPR17 expressed in human 1321N1 cells assessed as induction of [35S]GTPgammaS binding after 30 mins by rapid filtration ass...More data for this Ligand-Target Pair
TargetUracil nucleotide/cysteinyl leukotriene receptor(Homo sapiens (Human))
Northwest University
Curated by ChEMBL
Northwest University
Curated by ChEMBL
Affinity DataEC50: 11nMAssay Description:Agonist activity at human GPR17 expressed in human 1321N1 cells assessed as induction of [35S]GTPgammaS binding after 30 mins by rapid filtration ass...More data for this Ligand-Target Pair
TargetUracil nucleotide/cysteinyl leukotriene receptor(Homo sapiens (Human))
Northwest University
Curated by ChEMBL
Northwest University
Curated by ChEMBL
Affinity DataEC50: 1.70nMAssay Description:Agonist activity at human GPR17 expressed in human 1321N1 cells assessed as induction of [35S]GTPgammaS binding after 30 mins by rapid filtration ass...More data for this Ligand-Target Pair
TargetUracil nucleotide/cysteinyl leukotriene receptor(Homo sapiens (Human))
Northwest University
Curated by ChEMBL
Northwest University
Curated by ChEMBL
Affinity DataEC50: 1.40nMAssay Description:Agonist activity at human GPR17 expressed in human 1321N1 cells assessed as induction of [35S]GTPgammaS binding after 30 mins by rapid filtration ass...More data for this Ligand-Target Pair
TargetUracil nucleotide/cysteinyl leukotriene receptor(Homo sapiens (Human))
Northwest University
Curated by ChEMBL
Northwest University
Curated by ChEMBL
Affinity DataEC50: 0.0360nMAssay Description:Agonist activity at human GPR17 expressed in human 1321N1 cells assessed as induction of [35S]GTPgammaS binding after 30 mins by rapid filtration ass...More data for this Ligand-Target Pair
TargetUracil nucleotide/cysteinyl leukotriene receptor(Homo sapiens (Human))
Northwest University
Curated by ChEMBL
Northwest University
Curated by ChEMBL
Affinity DataIC50: 582nMAssay Description:Antagonist activity at human GPR17 expressed in human 1321N1 cells assessed as inhibition of UDP-glucose-induced [35S]GTPgammaS binding after 30 mins...More data for this Ligand-Target Pair
TargetUracil nucleotide/cysteinyl leukotriene receptor(Homo sapiens (Human))
Northwest University
Curated by ChEMBL
Northwest University
Curated by ChEMBL
Affinity DataIC50: 508nMAssay Description:Antagonist activity at human GPR17 expressed in human 1321N1 cells assessed as inhibition of UDP-glucose-induced [35S]GTPgammaS binding after 30 mins...More data for this Ligand-Target Pair
TargetUracil nucleotide/cysteinyl leukotriene receptor(Homo sapiens (Human))
Northwest University
Curated by ChEMBL
Northwest University
Curated by ChEMBL
Affinity DataIC50: 112nMAssay Description:Antagonist activity at human GPR17 expressed in human 1321N1 cells assessed as inhibition of UDP-glucose-induced [35S]GTPgammaS binding after 30 mins...More data for this Ligand-Target Pair
TargetUracil nucleotide/cysteinyl leukotriene receptor(Homo sapiens (Human))
Northwest University
Curated by ChEMBL
Northwest University
Curated by ChEMBL
Affinity DataIC50: 0.700nMAssay Description:Antagonist activity at human GPR17 expressed in human 1321N1 cells assessed as inhibition of UDP-glucose-induced [35S]GTPgammaS binding after 30 mins...More data for this Ligand-Target Pair
TargetUracil nucleotide/cysteinyl leukotriene receptor(Homo sapiens (Human))
Northwest University
Curated by ChEMBL
Northwest University
Curated by ChEMBL
Affinity DataEC50: 1.47E+3nMAssay Description:Agonist activity at human GPR17 expressed in human 1321N1 cells assessed as induction of calcium mobilization after 1 hr by Oregon Green BAPTA-1/AM d...More data for this Ligand-Target Pair
TargetUracil nucleotide/cysteinyl leukotriene receptor(Homo sapiens (Human))
Northwest University
Curated by ChEMBL
Northwest University
Curated by ChEMBL
Affinity DataEC50: 9.55E+3nMAssay Description:Agonist activity at human GPR17 expressed in human 1321N1 cells assessed as induction of calcium mobilization after 1 hr by Oregon Green BAPTA-1/AM d...More data for this Ligand-Target Pair
TargetUracil nucleotide/cysteinyl leukotriene receptor(Homo sapiens (Human))
Northwest University
Curated by ChEMBL
Northwest University
Curated by ChEMBL
Affinity DataIC50: >3.00E+4nMAssay Description:Antagonist activity at human GPR17 expressed in human 1321N1 cells assessed as inhibition of MDL 29,951-induced calcium mobilization after 1 hr by Or...More data for this Ligand-Target Pair
TargetUracil nucleotide/cysteinyl leukotriene receptor(Homo sapiens (Human))
Northwest University
Curated by ChEMBL
Northwest University
Curated by ChEMBL
Affinity DataEC50: 624nMAssay Description:Agonist activity at human GPR17 expressed in human 1321N1 cells assessed as induction of calcium mobilization after 1 hr by Oregon Green BAPTA-1/AM d...More data for this Ligand-Target Pair
TargetUracil nucleotide/cysteinyl leukotriene receptor(Homo sapiens (Human))
Northwest University
Curated by ChEMBL
Northwest University
Curated by ChEMBL
Affinity DataEC50: >3.00E+4nMAssay Description:Agonist activity at human GPR17 expressed in human 1321N1 cells assessed as induction of calcium mobilization after 1 hr by Oregon Green BAPTA-1/AM d...More data for this Ligand-Target Pair
TargetUracil nucleotide/cysteinyl leukotriene receptor(Rattus norvegicus)
Sultan Qaboos University
Curated by ChEMBL
Sultan Qaboos University
Curated by ChEMBL
Affinity DataEC50: 5.31E+3nMAssay Description:Agonist activity at rat GPR17 expressed in HEK293 cells assessed as induction of intracellular calcium mobilization by calcium 5-dye based assayMore data for this Ligand-Target Pair
TargetUracil nucleotide/cysteinyl leukotriene receptor(Rattus norvegicus)
Sultan Qaboos University
Curated by ChEMBL
Sultan Qaboos University
Curated by ChEMBL
Affinity DataEC50: 2.30E+3nMAssay Description:Agonist activity at rat GPR17 expressed in HEK293 cells assessed as induction of intracellular calcium mobilization by calcium 5-dye based assayMore data for this Ligand-Target Pair
TargetUracil nucleotide/cysteinyl leukotriene receptor(Mus musculus)
Sultan Qaboos University
Curated by ChEMBL
Sultan Qaboos University
Curated by ChEMBL
Affinity DataEC50: 1.11E+3nMAssay Description:Agonist activity at mouse GPR17 expressed in HEK293 cells assessed as induction of intracellular calcium mobilization by calcium 5-dye based assayMore data for this Ligand-Target Pair
TargetUracil nucleotide/cysteinyl leukotriene receptor(Homo sapiens (Human))
Northwest University
Curated by ChEMBL
Northwest University
Curated by ChEMBL
Affinity DataEC50: >3.00E+4nMAssay Description:Agonist activity at human GPR17 expressed in human 1321N1 cells assessed as induction of calcium mobilization after 1 hr by Oregon Green BAPTA-1/AM d...More data for this Ligand-Target Pair
TargetUracil nucleotide/cysteinyl leukotriene receptor(Homo sapiens (Human))
Northwest University
Curated by ChEMBL
Northwest University
Curated by ChEMBL
Affinity DataEC50: >3.00E+4nMAssay Description:Agonist activity at human GPR17 expressed in human 1321N1 cells assessed as induction of calcium mobilization after 1 hr by Oregon Green BAPTA-1/AM d...More data for this Ligand-Target Pair
TargetUracil nucleotide/cysteinyl leukotriene receptor(Homo sapiens (Human))
Northwest University
Curated by ChEMBL
Northwest University
Curated by ChEMBL
Affinity DataEC50: >3.00E+4nMAssay Description:Agonist activity at human GPR17 expressed in human 1321N1 cells assessed as induction of calcium mobilization after 1 hr by Oregon Green BAPTA-1/AM d...More data for this Ligand-Target Pair
TargetUracil nucleotide/cysteinyl leukotriene receptor(Homo sapiens (Human))
Northwest University
Curated by ChEMBL
Northwest University
Curated by ChEMBL
Affinity DataEC50: 7.41E+3nMAssay Description:Agonist activity at human GPR17 expressed in human 1321N1 cells assessed as induction of calcium mobilization after 1 hr by Oregon Green BAPTA-1/AM d...More data for this Ligand-Target Pair
TargetUracil nucleotide/cysteinyl leukotriene receptor(Homo sapiens (Human))
Northwest University
Curated by ChEMBL
Northwest University
Curated by ChEMBL
Affinity DataEC50: 1.51E+4nMAssay Description:Agonist activity at human GPR17 expressed in human 1321N1 cells assessed as induction of calcium mobilization after 1 hr by Oregon Green BAPTA-1/AM d...More data for this Ligand-Target Pair
TargetUracil nucleotide/cysteinyl leukotriene receptor(Homo sapiens (Human))
Northwest University
Curated by ChEMBL
Northwest University
Curated by ChEMBL
Affinity DataEC50: 3.72E+3nMAssay Description:Agonist activity at human GPR17 expressed in human 1321N1 cells assessed as induction of calcium mobilization after 1 hr by Oregon Green BAPTA-1/AM d...More data for this Ligand-Target Pair
TargetUracil nucleotide/cysteinyl leukotriene receptor(Homo sapiens (Human))
Northwest University
Curated by ChEMBL
Northwest University
Curated by ChEMBL
Affinity DataEC50: >3.00E+4nMAssay Description:Agonist activity at human GPR17 expressed in human 1321N1 cells assessed as induction of calcium mobilization after 1 hr by Oregon Green BAPTA-1/AM d...More data for this Ligand-Target Pair
TargetUracil nucleotide/cysteinyl leukotriene receptor(Homo sapiens (Human))
Northwest University
Curated by ChEMBL
Northwest University
Curated by ChEMBL
Affinity DataEC50: >3.00E+4nMAssay Description:Agonist activity at human GPR17 expressed in human 1321N1 cells assessed as induction of calcium mobilization after 1 hr by Oregon Green BAPTA-1/AM d...More data for this Ligand-Target Pair
TargetUracil nucleotide/cysteinyl leukotriene receptor(Homo sapiens (Human))
Northwest University
Curated by ChEMBL
Northwest University
Curated by ChEMBL
Affinity DataEC50: >1.00E+5nMAssay Description:Agonist activity at human GPR17 expressed in human 1321N1 cells assessed as induction of calcium mobilization after 1 hr by Oregon Green BAPTA-1/AM d...More data for this Ligand-Target Pair
TargetUracil nucleotide/cysteinyl leukotriene receptor(Homo sapiens (Human))
Northwest University
Curated by ChEMBL
Northwest University
Curated by ChEMBL
Affinity DataEC50: >1.00E+5nMAssay Description:Agonist activity at human GPR17 expressed in human 1321N1 cells assessed as induction of calcium mobilization after 1 hr by Oregon Green BAPTA-1/AM d...More data for this Ligand-Target Pair
TargetUracil nucleotide/cysteinyl leukotriene receptor(Homo sapiens (Human))
Northwest University
Curated by ChEMBL
Northwest University
Curated by ChEMBL
Affinity DataEC50: >1.00E+5nMAssay Description:Agonist activity at human GPR17 expressed in human 1321N1 cells assessed as induction of calcium mobilization after 1 hr by Oregon Green BAPTA-1/AM d...More data for this Ligand-Target Pair
TargetUracil nucleotide/cysteinyl leukotriene receptor(Homo sapiens (Human))
Northwest University
Curated by ChEMBL
Northwest University
Curated by ChEMBL
Affinity DataEC50: 4.83E+3nMAssay Description:Agonist activity at human GPR17 expressed in human 1321N1 cells assessed as induction of calcium mobilization after 1 hr by Oregon Green BAPTA-1/AM d...More data for this Ligand-Target Pair
TargetUracil nucleotide/cysteinyl leukotriene receptor(Homo sapiens (Human))
Northwest University
Curated by ChEMBL
Northwest University
Curated by ChEMBL
Affinity DataEC50: 32nMAssay Description:Agonist activity at human GPR17 expressed in human 1321N1 cells assessed as induction of calcium mobilization after 1 hr by Oregon Green BAPTA-1/AM d...More data for this Ligand-Target Pair
TargetUracil nucleotide/cysteinyl leukotriene receptor(Homo sapiens (Human))
Northwest University
Curated by ChEMBL
Northwest University
Curated by ChEMBL
Affinity DataEC50: 423nMAssay Description:Agonist activity at human GPR17 expressed in human 1321N1 cells assessed as induction of calcium mobilization after 1 hr by Oregon Green BAPTA-1/AM d...More data for this Ligand-Target Pair
TargetUracil nucleotide/cysteinyl leukotriene receptor(Homo sapiens (Human))
Northwest University
Curated by ChEMBL
Northwest University
Curated by ChEMBL
Affinity DataEC50: 115nMAssay Description:Agonist activity at human GPR17 expressed in human 1321N1 cells assessed as induction of calcium mobilization after 1 hr by Oregon Green BAPTA-1/AM d...More data for this Ligand-Target Pair
TargetUracil nucleotide/cysteinyl leukotriene receptor(Homo sapiens (Human))
Northwest University
Curated by ChEMBL
Northwest University
Curated by ChEMBL
Affinity DataEC50: 67nMAssay Description:Agonist activity at human GPR17 expressed in human 1321N1 cells assessed as induction of calcium mobilization after 1 hr by Oregon Green BAPTA-1/AM d...More data for this Ligand-Target Pair
TargetUracil nucleotide/cysteinyl leukotriene receptor(Homo sapiens (Human))
Northwest University
Curated by ChEMBL
Northwest University
Curated by ChEMBL
Affinity DataEC50: 117nMAssay Description:Agonist activity at human GPR17 expressed in human 1321N1 cells assessed as induction of calcium mobilization after 1 hr by Oregon Green BAPTA-1/AM d...More data for this Ligand-Target Pair
TargetUracil nucleotide/cysteinyl leukotriene receptor(Homo sapiens (Human))
Northwest University
Curated by ChEMBL
Northwest University
Curated by ChEMBL
Affinity DataEC50: >1.00E+5nMAssay Description:Agonist activity at human GPR17 expressed in human 1321N1 cells assessed as induction of calcium mobilization after 1 hr by Oregon Green BAPTA-1/AM d...More data for this Ligand-Target Pair
TargetUracil nucleotide/cysteinyl leukotriene receptor(Homo sapiens (Human))
Northwest University
Curated by ChEMBL
Northwest University
Curated by ChEMBL
Affinity DataEC50: 4.02E+3nMAssay Description:Agonist activity at human GPR17 expressed in human 1321N1 cells assessed as induction of calcium mobilization after 1 hr by Oregon Green BAPTA-1/AM d...More data for this Ligand-Target Pair
TargetUracil nucleotide/cysteinyl leukotriene receptor(Homo sapiens (Human))
Northwest University
Curated by ChEMBL
Northwest University
Curated by ChEMBL
Affinity DataEC50: 3.01E+3nMAssay Description:Agonist activity at human GPR17 expressed in human 1321N1 cells assessed as induction of calcium mobilization after 1 hr by Oregon Green BAPTA-1/AM d...More data for this Ligand-Target Pair
TargetUracil nucleotide/cysteinyl leukotriene receptor(Homo sapiens (Human))
Northwest University
Curated by ChEMBL
Northwest University
Curated by ChEMBL
Affinity DataEC50: 1.44E+4nMAssay Description:Agonist activity at human GPR17 expressed in human 1321N1 cells assessed as induction of calcium mobilization after 1 hr by Oregon Green BAPTA-1/AM d...More data for this Ligand-Target Pair