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Found 3228 Enz. Inhib. hit(s) with Target = 'C-C chemokine receptor type 2'
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM140256(US8906911, 65)
Affinity DataKi:  6nM ΔG°:  -43.6kJ/mole IC50:  28nMpH: 7.4 T: 2°CAssay Description:Radioligand binding assays were performed in CHO cells expressing human CCR2B and Galpha±16 coupling protein. All compounds were dissolved in DMSO a...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM140239(US8906911, 48)
Affinity DataKi:  8nM ΔG°:  -43.0kJ/mole IC50:  51.8nMpH: 7.4 T: 2°CAssay Description:Radioligand binding assays were performed in CHO cells expressing human CCR2B and Galpha±16 coupling protein. All compounds were dissolved in DMSO a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM140254(US8906911, 63)
Affinity DataKi:  10nM ΔG°:  -42.4kJ/mole IC50:  17.9nMpH: 7.4 T: 2°CAssay Description:Radioligand binding assays were performed in CHO cells expressing human CCR2B and Galpha±16 coupling protein. All compounds were dissolved in DMSO a...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM140255(US8906911, 64)
Affinity DataKi:  12nM ΔG°:  -42.0kJ/mole IC50:  16.5nMpH: 7.4 T: 2°CAssay Description:Radioligand binding assays were performed in CHO cells expressing human CCR2B and Galpha±16 coupling protein. All compounds were dissolved in DMSO a...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM140257(US8906911, 66)
Affinity DataKi:  13nM ΔG°:  -41.8kJ/mole IC50:  45.8nMpH: 7.4 T: 2°CAssay Description:Radioligand binding assays were performed in CHO cells expressing human CCR2B and Galpha±16 coupling protein. All compounds were dissolved in DMSO a...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM140240(US8906911, 49)
Affinity DataKi:  15nM ΔG°:  -41.5kJ/mole IC50:  37nMpH: 7.4 T: 2°CAssay Description:Radioligand binding assays were performed in CHO cells expressing human CCR2B and Galpha±16 coupling protein. All compounds were dissolved in DMSO a...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM140244(US8906911, 53)
Affinity DataKi:  16nM ΔG°:  -41.4kJ/mole IC50:  47.9nMpH: 7.4 T: 2°CAssay Description:Radioligand binding assays were performed in CHO cells expressing human CCR2B and Galpha±16 coupling protein. All compounds were dissolved in DMSO a...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM140237(US8906911, 46)
Affinity DataKi:  17nM ΔG°:  -41.2kJ/mole IC50:  17.6nMpH: 7.4 T: 2°CAssay Description:Radioligand binding assays were performed in CHO cells expressing human CCR2B and Galpha±16 coupling protein. All compounds were dissolved in DMSO a...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM140242(US8906911, 51)
Affinity DataKi:  21nM ΔG°:  -40.7kJ/mole IC50:  43.3nMpH: 7.4 T: 2°CAssay Description:Radioligand binding assays were performed in CHO cells expressing human CCR2B and Galpha±16 coupling protein. All compounds were dissolved in DMSO a...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM140197(US8906911, 6)
Affinity DataKi:  28nM ΔG°:  -40.1kJ/mole IC50:  32.8nMpH: 7.4 T: 2°CAssay Description:Radioligand binding assays were performed in CHO cells expressing human CCR2B and Galpha±16 coupling protein. All compounds were dissolved in DMSO a...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM140206(US8906911, 15)
Affinity DataKi:  29nM ΔG°:  -40.0kJ/mole IC50:  34.7nMpH: 7.4 T: 2°CAssay Description:Radioligand binding assays were performed in CHO cells expressing human CCR2B and Galpha±16 coupling protein. All compounds were dissolved in DMSO a...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM140198(US8906911, 7)
Affinity DataKi:  30nM ΔG°:  -39.9kJ/mole IC50:  65.7nMpH: 7.4 T: 2°CAssay Description:Radioligand binding assays were performed in CHO cells expressing human CCR2B and Galpha±16 coupling protein. All compounds were dissolved in DMSO a...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM140205(US8906911, 14)
Affinity DataKi:  31nM ΔG°:  -39.8kJ/mole IC50:  43nMpH: 7.4 T: 2°CAssay Description:Radioligand binding assays were performed in CHO cells expressing human CCR2B and Galpha±16 coupling protein. All compounds were dissolved in DMSO a...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM140219(US8906911, 28)
Affinity DataKi:  32nM ΔG°:  -39.8kJ/mole IC50:  19.8nMpH: 7.4 T: 2°CAssay Description:Radioligand binding assays were performed in CHO cells expressing human CCR2B and Galpha±16 coupling protein. All compounds were dissolved in DMSO a...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM140192(US8906911, 1)
Affinity DataKi:  32nM ΔG°:  -39.8kJ/mole IC50:  54.9nMpH: 7.4 T: 2°CAssay Description:Radioligand binding assays were performed in CHO cells expressing human CCR2B and Galpha±16 coupling protein. All compounds were dissolved in DMSO a...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM140247(US8906911, 56)
Affinity DataKi:  32nM ΔG°:  -39.8kJ/mole IC50:  46nMpH: 7.4 T: 2°CAssay Description:Radioligand binding assays were performed in CHO cells expressing human CCR2B and Galpha±16 coupling protein. All compounds were dissolved in DMSO a...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM140231(US8906911, 40)
Affinity DataKi:  38nM ΔG°:  -39.4kJ/mole IC50:  41.5nMpH: 7.4 T: 2°CAssay Description:Radioligand binding assays were performed in CHO cells expressing human CCR2B and Galpha±16 coupling protein. All compounds were dissolved in DMSO a...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM140243(US8906911, 52)
Affinity DataKi:  49nM ΔG°:  -38.8kJ/mole IC50:  83.9nMpH: 7.4 T: 2°CAssay Description:Radioligand binding assays were performed in CHO cells expressing human CCR2B and Galpha±16 coupling protein. All compounds were dissolved in DMSO a...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM140193(US8906911, 2)
Affinity DataKi:  60nM ΔG°:  -38.3kJ/mole IC50:  76.7nMpH: 7.4 T: 2°CAssay Description:Radioligand binding assays were performed in CHO cells expressing human CCR2B and Galpha±16 coupling protein. All compounds were dissolved in DMSO a...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM140230(US8906911, 39)
Affinity DataKi:  66nM ΔG°:  -38.1kJ/mole IC50:  55.3nMpH: 7.4 T: 2°CAssay Description:Radioligand binding assays were performed in CHO cells expressing human CCR2B and Galpha±16 coupling protein. All compounds were dissolved in DMSO a...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM140252(US8906911, 61)
Affinity DataKi:  69nM ΔG°:  -38.0kJ/mole IC50:  100nMpH: 7.4 T: 2°CAssay Description:Radioligand binding assays were performed in CHO cells expressing human CCR2B and Galpha±16 coupling protein. All compounds were dissolved in DMSO a...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM140238(US8906911, 47)
Affinity DataKi:  77nM ΔG°:  -37.7kJ/mole IC50:  49.8nMpH: 7.4 T: 2°CAssay Description:Radioligand binding assays were performed in CHO cells expressing human CCR2B and Galpha±16 coupling protein. All compounds were dissolved in DMSO a...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM140241(US8906911, 50)
Affinity DataKi:  78nM ΔG°:  -37.7kJ/mole IC50:  25.9nMpH: 7.4 T: 2°CAssay Description:Radioligand binding assays were performed in CHO cells expressing human CCR2B and Galpha±16 coupling protein. All compounds were dissolved in DMSO a...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM140196(US8906911, 5)
Affinity DataKi:  104nM ΔG°:  -37.0kJ/mole IC50:  140nMpH: 7.4 T: 2°CAssay Description:Radioligand binding assays were performed in CHO cells expressing human CCR2B and Galpha±16 coupling protein. All compounds were dissolved in DMSO a...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM140211(US8906911, 20)
Affinity DataKi:  112nM ΔG°:  -36.9kJ/mole IC50:  182nMpH: 7.4 T: 2°CAssay Description:Radioligand binding assays were performed in CHO cells expressing human CCR2B and Galpha±16 coupling protein. All compounds were dissolved in DMSO a...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM140213(US8906911, 22)
Affinity DataKi:  120nM ΔG°:  -36.7kJ/mole IC50:  153nMpH: 7.4 T: 2°CAssay Description:Radioligand binding assays were performed in CHO cells expressing human CCR2B and Galpha±16 coupling protein. All compounds were dissolved in DMSO a...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM140207(US8906911, 16)
Affinity DataKi:  199nM ΔG°:  -35.6kJ/mole IC50:  106nMpH: 7.4 T: 2°CAssay Description:Radioligand binding assays were performed in CHO cells expressing human CCR2B and Galpha±16 coupling protein. All compounds were dissolved in DMSO a...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM140209(US8906911, 18)
Affinity DataKi:  207nM ΔG°:  -35.5kJ/mole IC50:  76.4nMpH: 7.4 T: 2°CAssay Description:Radioligand binding assays were performed in CHO cells expressing human CCR2B and Galpha±16 coupling protein. All compounds were dissolved in DMSO a...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM140203(US8906911, 12)
Affinity DataKi:  261nM ΔG°:  -34.9kJ/mole IC50:  194nMpH: 7.4 T: 2°CAssay Description:Radioligand binding assays were performed in CHO cells expressing human CCR2B and Galpha±16 coupling protein. All compounds were dissolved in DMSO a...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM140216(US8906911, 25)
Affinity DataKi:  271nM ΔG°:  -34.8kJ/mole IC50:  92.2nMpH: 7.4 T: 2°CAssay Description:Radioligand binding assays were performed in CHO cells expressing human CCR2B and Galpha±16 coupling protein. All compounds were dissolved in DMSO a...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM140210(US8906911, 19)
Affinity DataKi:  306nM ΔG°:  -34.6kJ/mole IC50:  233nMpH: 7.4 T: 2°CAssay Description:Radioligand binding assays were performed in CHO cells expressing human CCR2B and Galpha±16 coupling protein. All compounds were dissolved in DMSO a...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM140218(US8906911, 27)
Affinity DataKi:  444nM ΔG°:  -33.7kJ/mole IC50:  391nMpH: 7.4 T: 2°CAssay Description:Radioligand binding assays were performed in CHO cells expressing human CCR2B and Galpha±16 coupling protein. All compounds were dissolved in DMSO a...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM140220(US8906911, 29)
Affinity DataKi:  473nM ΔG°:  -33.6kJ/mole IC50:  148nMpH: 7.4 T: 2°CAssay Description:Radioligand binding assays were performed in CHO cells expressing human CCR2B and Galpha±16 coupling protein. All compounds were dissolved in DMSO a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM140251(US8906911, 60)
Affinity DataKi:  552nM ΔG°:  -33.2kJ/mole IC50:  328nMpH: 7.4 T: 2°CAssay Description:Radioligand binding assays were performed in CHO cells expressing human CCR2B and Galpha±16 coupling protein. All compounds were dissolved in DMSO a...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM140204(US8906911, 13)
Affinity DataKi:  593nM ΔG°:  -33.0kJ/mole IC50:  525nMpH: 7.4 T: 2°CAssay Description:Radioligand binding assays were performed in CHO cells expressing human CCR2B and Galpha±16 coupling protein. All compounds were dissolved in DMSO a...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM140217(US8906911, 26)
Affinity DataKi:  792nM ΔG°:  -32.4kJ/mole IC50:  598nMpH: 7.4 T: 2°CAssay Description:Radioligand binding assays were performed in CHO cells expressing human CCR2B and Galpha±16 coupling protein. All compounds were dissolved in DMSO a...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM140221(US8906911, 30)
Affinity DataKi:  831nM ΔG°:  -32.3kJ/mole IC50:  95.5nMpH: 7.4 T: 2°CAssay Description:Radioligand binding assays were performed in CHO cells expressing human CCR2B and Galpha±16 coupling protein. All compounds were dissolved in DMSO a...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM140227(US8906911, 36)
Affinity DataKi:  1.06E+3nM ΔG°:  -31.7kJ/mole IC50:  305nMpH: 7.4 T: 2°CAssay Description:Radioligand binding assays were performed in CHO cells expressing human CCR2B and Galpha±16 coupling protein. All compounds were dissolved in DMSO a...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM140223(US8906911, 32)
Affinity DataKi:  1.06E+3nM ΔG°:  -31.7kJ/mole IC50:  314nMpH: 7.4 T: 2°CAssay Description:Radioligand binding assays were performed in CHO cells expressing human CCR2B and Galpha±16 coupling protein. All compounds were dissolved in DMSO a...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM140228(US8906911, 37)
Affinity DataIC50:  1.60E+3nMpH: 7.4 T: 2°CAssay Description:Radioligand binding assays were performed in CHO cells expressing human CCR2B and Galpha±16 coupling protein. All compounds were dissolved in DMSO a...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM140229(US8906911, 38)
Affinity DataIC50:  1.60E+3nMpH: 7.4 T: 2°CAssay Description:Radioligand binding assays were performed in CHO cells expressing human CCR2B and Galpha±16 coupling protein. All compounds were dissolved in DMSO a...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM140212(US8906911, 21)
Affinity DataIC50:  821nMpH: 7.4 T: 2°CAssay Description:Radioligand binding assays were performed in CHO cells expressing human CCR2B and Galpha±16 coupling protein. All compounds were dissolved in DMSO a...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM140208(US8906911, 17)
Affinity DataIC50:  1.29E+3nMpH: 7.4 T: 2°CAssay Description:Radioligand binding assays were performed in CHO cells expressing human CCR2B and Galpha±16 coupling protein. All compounds were dissolved in DMSO a...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM140232(US8906911, 41)
Affinity DataIC50:  2.50E+4nMpH: 7.4 T: 2°CAssay Description:Radioligand binding assays were performed in CHO cells expressing human CCR2B and Galpha±16 coupling protein. All compounds were dissolved in DMSO a...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM140233(US8906911, 42)
Affinity DataIC50:  812nMpH: 7.4 T: 2°CAssay Description:Radioligand binding assays were performed in CHO cells expressing human CCR2B and Galpha±16 coupling protein. All compounds were dissolved in DMSO a...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM140234(US8906911, 43)
Affinity DataIC50:  1.52E+3nMpH: 7.4 T: 2°CAssay Description:Radioligand binding assays were performed in CHO cells expressing human CCR2B and Galpha±16 coupling protein. All compounds were dissolved in DMSO a...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM140235(US8906911, 44)
Affinity DataIC50:  1.60E+3nMpH: 7.4 T: 2°CAssay Description:Radioligand binding assays were performed in CHO cells expressing human CCR2B and Galpha±16 coupling protein. All compounds were dissolved in DMSO a...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM140236(US8906911, 45)
Affinity DataIC50:  2.20E+3nMpH: 7.4 T: 2°CAssay Description:Radioligand binding assays were performed in CHO cells expressing human CCR2B and Galpha±16 coupling protein. All compounds were dissolved in DMSO a...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM140202(US8906911, 11)
Affinity DataIC50:  1.47E+3nMpH: 7.4 T: 2°CAssay Description:Radioligand binding assays were performed in CHO cells expressing human CCR2B and Galpha±16 coupling protein. All compounds were dissolved in DMSO a...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM140201(US8906911, 10)
Affinity DataIC50:  1.60E+3nMpH: 7.4 T: 2°CAssay Description:Radioligand binding assays were performed in CHO cells expressing human CCR2B and Galpha±16 coupling protein. All compounds were dissolved in DMSO a...More data for this Ligand-Target Pair
In DepthDetails US Patent
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