Affinity DataIC50: 1.10E+4nMpH: 7.5 T: 2°CAssay Description:For the DNA polymerase reaction, the dehydroaltenusin derivative was dissolved in dimethyl sulfoxide (DMSO) at various concentrations and sonicated f...More data for this Ligand-Target Pair
Affinity DataIC50: 2.40E+4nMpH: 7.5 T: 2°CAssay Description:For the DNA polymerase reaction, the dehydroaltenusin derivative was dissolved in dimethyl sulfoxide (DMSO) at various concentrations and sonicated f...More data for this Ligand-Target Pair
Affinity DataIC50: 3.50E+4nMpH: 7.5 T: 2°CAssay Description:For the DNA polymerase reaction, the dehydroaltenusin derivative was dissolved in dimethyl sulfoxide (DMSO) at various concentrations and sonicated f...More data for this Ligand-Target Pair
Affinity DataIC50: 1.26E+5nMpH: 7.5 T: 2°CAssay Description:For the DNA polymerase reaction, the dehydroaltenusin derivative was dissolved in dimethyl sulfoxide (DMSO) at various concentrations and sonicated f...More data for this Ligand-Target Pair
Affinity DataIC50: 8.90E+4nMpH: 7.5 T: 2°CAssay Description:For the DNA polymerase reaction, the dehydroaltenusin derivative was dissolved in dimethyl sulfoxide (DMSO) at various concentrations and sonicated f...More data for this Ligand-Target Pair
Affinity DataIC50: >2.00E+5nMpH: 7.5 T: 2°CAssay Description:For the DNA polymerase reaction, the dehydroaltenusin derivative was dissolved in dimethyl sulfoxide (DMSO) at various concentrations and sonicated f...More data for this Ligand-Target Pair
Affinity DataIC50: >2.00E+5nMpH: 7.5 T: 2°CAssay Description:For the DNA polymerase reaction, the dehydroaltenusin derivative was dissolved in dimethyl sulfoxide (DMSO) at various concentrations and sonicated f...More data for this Ligand-Target Pair
Affinity DataIC50: >2.00E+5nMpH: 7.5 T: 2°CAssay Description:For the DNA polymerase reaction, the dehydroaltenusin derivative was dissolved in dimethyl sulfoxide (DMSO) at various concentrations and sonicated f...More data for this Ligand-Target Pair
Affinity DataIC50: >2.00E+5nMpH: 7.5 T: 2°CAssay Description:For the DNA polymerase reaction, the dehydroaltenusin derivative was dissolved in dimethyl sulfoxide (DMSO) at various concentrations and sonicated f...More data for this Ligand-Target Pair
Affinity DataIC50: 6.40E+4nMpH: 7.5 T: 2°CAssay Description:For the DNA polymerase reaction, the dehydroaltenusin derivative was dissolved in dimethyl sulfoxide (DMSO) at various concentrations and sonicated f...More data for this Ligand-Target Pair
Affinity DataIC50: >5.00E+4nMpH: 7.9Assay Description:Pol β reactions were made in a final volume of 20uL containing 50mM Tris-HCl pH 7.9, 20mM KCl, 5% (v/v) glycerol, 1mM DTT, 2mM MnCl2, 250nM puri...More data for this Ligand-Target Pair
Affinity DataIC50: >5.00E+4nMpH: 7.9Assay Description:Pol β reactions were made in a final volume of 20uL containing 50mM Tris-HCl pH 7.9, 20mM KCl, 5% (v/v) glycerol, 1mM DTT, 2mM MnCl2, 250nM puri...More data for this Ligand-Target Pair
Affinity DataIC50: >5.00E+4nMpH: 7.9Assay Description:Pol β reactions were made in a final volume of 20uL containing 50mM Tris-HCl pH 7.9, 20mM KCl, 5% (v/v) glycerol, 1mM DTT, 2mM MnCl2, 250nM puri...More data for this Ligand-Target Pair
Affinity DataIC50: >5.00E+4nMpH: 7.9Assay Description:Pol β reactions were made in a final volume of 20uL containing 50mM Tris-HCl pH 7.9, 20mM KCl, 5% (v/v) glycerol, 1mM DTT, 2mM MnCl2, 250nM puri...More data for this Ligand-Target Pair
Affinity DataIC50: 2.98E+4nMpH: 7.9Assay Description:Pol β reactions were made in a final volume of 20uL containing 50mM Tris-HCl pH 7.9, 20mM KCl, 5% (v/v) glycerol, 1mM DTT, 2mM MnCl2, 250nM puri...More data for this Ligand-Target Pair
Affinity DataIC50: <5.00E+4nMpH: 7.9Assay Description:Pol β reactions were made in a final volume of 20uL containing 50mM Tris-HCl pH 7.9, 20mM KCl, 5% (v/v) glycerol, 1mM DTT, 2mM MnCl2, 250nM puri...More data for this Ligand-Target Pair
Affinity DataIC50: 2.81E+4nMpH: 7.9Assay Description:Pol β reactions were made in a final volume of 20uL containing 50mM Tris-HCl pH 7.9, 20mM KCl, 5% (v/v) glycerol, 1mM DTT, 2mM MnCl2, 250nM puri...More data for this Ligand-Target Pair
Affinity DataIC50: >5.00E+4nMpH: 7.9Assay Description:Pol β reactions were made in a final volume of 20uL containing 50mM Tris-HCl pH 7.9, 20mM KCl, 5% (v/v) glycerol, 1mM DTT, 2mM MnCl2, 250nM puri...More data for this Ligand-Target Pair
Affinity DataIC50: >5.00E+4nMpH: 7.9Assay Description:Pol β reactions were made in a final volume of 20uL containing 50mM Tris-HCl pH 7.9, 20mM KCl, 5% (v/v) glycerol, 1mM DTT, 2mM MnCl2, 250nM puri...More data for this Ligand-Target Pair
Affinity DataIC50: 3.87E+4nMpH: 7.9Assay Description:Pol β reactions were made in a final volume of 20uL containing 50mM Tris-HCl pH 7.9, 20mM KCl, 5% (v/v) glycerol, 1mM DTT, 2mM MnCl2, 250nM puri...More data for this Ligand-Target Pair
Affinity DataIC50: <5.00E+4nMpH: 7.9Assay Description:Pol β reactions were made in a final volume of 20uL containing 50mM Tris-HCl pH 7.9, 20mM KCl, 5% (v/v) glycerol, 1mM DTT, 2mM MnCl2, 250nM puri...More data for this Ligand-Target Pair
Affinity DataIC50: <5.00E+4nMpH: 7.9Assay Description:Pol β reactions were made in a final volume of 20uL containing 50mM Tris-HCl pH 7.9, 20mM KCl, 5% (v/v) glycerol, 1mM DTT, 2mM MnCl2, 250nM puri...More data for this Ligand-Target Pair
Affinity DataIC50: >5.00E+4nMpH: 7.9Assay Description:Pol β reactions were made in a final volume of 20uL containing 50mM Tris-HCl pH 7.9, 20mM KCl, 5% (v/v) glycerol, 1mM DTT, 2mM MnCl2, 250nM puri...More data for this Ligand-Target Pair
Affinity DataIC50: <5.00E+4nMpH: 7.9Assay Description:Pol β reactions were made in a final volume of 20uL containing 50mM Tris-HCl pH 7.9, 20mM KCl, 5% (v/v) glycerol, 1mM DTT, 2mM MnCl2, 250nM puri...More data for this Ligand-Target Pair
Affinity DataIC50: 6.44E+4nMpH: 7.9Assay Description:Pol β reactions were made in a final volume of 20uL containing 50mM Tris-HCl pH 7.9, 20mM KCl, 5% (v/v) glycerol, 1mM DTT, 2mM MnCl2, 250nM puri...More data for this Ligand-Target Pair
Affinity DataIC50: 1.82E+4nMpH: 7.9Assay Description:Pol β reactions were made in a final volume of 20uL containing 50mM Tris-HCl pH 7.9, 20mM KCl, 5% (v/v) glycerol, 1mM DTT, 2mM MnCl2, 250nM puri...More data for this Ligand-Target Pair
Affinity DataIC50: <5.00E+4nMpH: 7.9Assay Description:Pol β reactions were made in a final volume of 20uL containing 50mM Tris-HCl pH 7.9, 20mM KCl, 5% (v/v) glycerol, 1mM DTT, 2mM MnCl2, 250nM puri...More data for this Ligand-Target Pair
Affinity DataIC50: <5.00E+4nMpH: 7.9Assay Description:Pol β reactions were made in a final volume of 20uL containing 50mM Tris-HCl pH 7.9, 20mM KCl, 5% (v/v) glycerol, 1mM DTT, 2mM MnCl2, 250nM puri...More data for this Ligand-Target Pair
Affinity DataIC50: <5.00E+4nMpH: 7.9Assay Description:Pol β reactions were made in a final volume of 20uL containing 50mM Tris-HCl pH 7.9, 20mM KCl, 5% (v/v) glycerol, 1mM DTT, 2mM MnCl2, 250nM puri...More data for this Ligand-Target Pair
Affinity DataIC50: 5.00E+4nMpH: 7.9Assay Description:Pol β reactions were made in a final volume of 20uL containing 50mM Tris-HCl pH 7.9, 20mM KCl, 5% (v/v) glycerol, 1mM DTT, 2mM MnCl2, 250nM puri...More data for this Ligand-Target Pair
Affinity DataIC50: 5.00E+4nMpH: 7.9Assay Description:Pol β reactions were made in a final volume of 20uL containing 50mM Tris-HCl pH 7.9, 20mM KCl, 5% (v/v) glycerol, 1mM DTT, 2mM MnCl2, 250nM puri...More data for this Ligand-Target Pair
Affinity DataIC50: >5.00E+4nMpH: 7.9Assay Description:Pol β reactions were made in a final volume of 20uL containing 50mM Tris-HCl pH 7.9, 20mM KCl, 5% (v/v) glycerol, 1mM DTT, 2mM MnCl2, 250nM puri...More data for this Ligand-Target Pair
Affinity DataIC50: >5.00E+4nMpH: 7.9Assay Description:Pol β reactions were made in a final volume of 20uL containing 50mM Tris-HCl pH 7.9, 20mM KCl, 5% (v/v) glycerol, 1mM DTT, 2mM MnCl2, 250nM puri...More data for this Ligand-Target Pair
Affinity DataIC50: >5.00E+4nMpH: 7.9Assay Description:Pol β reactions were made in a final volume of 20uL containing 50mM Tris-HCl pH 7.9, 20mM KCl, 5% (v/v) glycerol, 1mM DTT, 2mM MnCl2, 250nM puri...More data for this Ligand-Target Pair
Affinity DataIC50: <5.00E+4nMpH: 7.9Assay Description:Pol β reactions were made in a final volume of 20uL containing 50mM Tris-HCl pH 7.9, 20mM KCl, 5% (v/v) glycerol, 1mM DTT, 2mM MnCl2, 250nM puri...More data for this Ligand-Target Pair
Affinity DataKi: 390nMAssay Description:Inhibition of DNA polymerase beta from human KB3 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 600nMAssay Description:Inhibition of human DNA polymerase betaMore data for this Ligand-Target Pair
Affinity DataKi: 900nMAssay Description:Inhibition of human DNA polymerase betaMore data for this Ligand-Target Pair
Affinity DataKi: 1.00E+3nMAssay Description:Inhibition of human DNA polymerase betaMore data for this Ligand-Target Pair
Affinity DataKi: 2.80E+3nMAssay Description:Inhibition of rat recombinant DNA polymerase beta after 20 mins by uncompetitive inhibition assay in presence of activated calf thymus DNA and 0.1 mg...More data for this Ligand-Target Pair
Affinity DataKi: 4.70E+3nMAssay Description:Inhibition constant of the compound was determined at a concentration of 5 microM on rat DNA polymerase beta as a function of template primer doseMore data for this Ligand-Target Pair
Affinity DataKi: 5.00E+3nMAssay Description:Inhibition of human DNA polymerase betaMore data for this Ligand-Target Pair
Affinity DataKi: 5.50E+3nMAssay Description:Competitive inhibition of recombinant rat DNA polymerase beta using poly(dA)/oligo(dT)18 as substrate by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
Affinity DataKi: 6.60E+3nMAssay Description:Inhibition constant of the compound was determined at a concentration of 10 microM on rat DNA polymerase beta as a function of nucleotide substrate c...More data for this Ligand-Target Pair
Affinity DataKi: 1.10E+4nMAssay Description:Activity of rat recombinant DNA polymerase beta using variable levels of DNA template-primerMore data for this Ligand-Target Pair
Affinity DataKi: 1.16E+4nMAssay Description:Noncompetitive inhibition of recombinant rat DNA polymerase beta using dTTP as substrate by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
Affinity DataKi: 1.20E+4nMAssay Description:Activity of rat recombinant DNA polymerase beta using variable levels of DNA template-primerMore data for this Ligand-Target Pair
Affinity DataKi: 1.28E+4nMAssay Description:Inhibition constant of the compound was determined at a concentration of 5 microM on rat DNA polymerase beta as a function of template primer doseMore data for this Ligand-Target Pair
Affinity DataKi: 1.50E+4nMAssay Description:Inhibition of rat recombinant DNA polymerase beta after 20 mins by noncompetitive inhibition assay in presence of activated calf thymus DNA and 0.1 m...More data for this Ligand-Target Pair
Affinity DataKi: 2.01E+4nMAssay Description:Inhibition constant of the compound was determined at a concentration of 10 microM on rat DNA polymerase beta as a function of template primer doseMore data for this Ligand-Target Pair