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Found 23 Enz. Inhib. hit(s) with Target = 'Hyaluronidase'
TargetHyaluronidase-1(Homo sapiens (Human))
TBA

LigandPNGBDBM81867(N-Substituted indole-2- and 3-carboxamide derivati...)
Affinity DataIC50:  7.29E+4nMpH: 3.5 T: 2°CAssay Description:Morgan-elson assay were used to test inhibitors at pH of 3.5.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHyaluronidase-1(Homo sapiens (Human))
TBA

LigandPNGBDBM81866(N-Substituted indole-2- and 3-carboxamide derivati...)
Affinity DataIC50:  6.16E+4nMpH: 3.5 T: 2°CAssay Description:Morgan-elson assay were used to test inhibitors at pH of 3.5.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHyaluronidase-1(Homo sapiens (Human))
TBA

LigandPNGBDBM81861(N-Substituted indole-2- and 3-carboxamide derivati...)
Affinity DataIC50:  6.43E+4nMpH: 3.5 T: 2°CAssay Description:Morgan-elson assay were used to test inhibitors at pH of 3.5.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHyaluronidase-1(Homo sapiens (Human))
TBA

LigandPNGBDBM81860(N-Substituted indole-2- and 3-carboxamide derivati...)
Affinity DataIC50:  7.82E+4nMpH: 3.5 T: 2°CAssay Description:Morgan-elson assay were used to test inhibitors at pH of 3.5.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHyaluronidase-1(Homo sapiens (Human))
TBA

LigandPNGBDBM81868(N-Substituted indole-2- and 3-carboxamide derivati...)
Affinity DataIC50:  5.67E+4nMpH: 3.5 T: 2°CAssay Description:Morgan-elson assay were used to test inhibitors at pH of 3.5.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHyaluronidase-1(Homo sapiens (Human))
TBA

LigandPNGBDBM81866(N-Substituted indole-2- and 3-carboxamide derivati...)
Affinity DataIC50:  3.30E+4nMpH: 7.0 T: 2°CAssay Description:Stains-all assay were used to test inhibitors at pH of 7.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHyaluronidase-1(Homo sapiens (Human))
TBA

LigandPNGBDBM81867(N-Substituted indole-2- and 3-carboxamide derivati...)
Affinity DataIC50:  3.37E+4nMpH: 7.0 T: 2°CAssay Description:Stains-all assay were used to test inhibitors at pH of 7.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHyaluronidase-1(Homo sapiens (Human))
TBA

LigandPNGBDBM81868(N-Substituted indole-2- and 3-carboxamide derivati...)
Affinity DataIC50:  2.57E+4nMpH: 7.0 T: 2°CAssay Description:Stains-all assay were used to test inhibitors at pH of 7.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHyaluronidase-1(Homo sapiens (Human))
TBA

LigandPNGBDBM81865(N-Substituted indole-2- and 3-carboxamide derivati...)
Affinity DataIC50:  2.99E+4nMpH: 7.0 T: 2°CAssay Description:Stains-all assay were used to test inhibitors at pH of 7.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHyaluronidase-1(Homo sapiens (Human))
TBA

LigandPNGBDBM81864(N-Substituted indole-2- and 3-carboxamide derivati...)
Affinity DataIC50:  3.30E+4nMpH: 7.0 T: 2°CAssay Description:Stains-all assay were used to test inhibitors at pH of 7.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHyaluronidase-1(Homo sapiens (Human))
TBA

LigandPNGBDBM81863(N-Substituted indole-2- and 3-carboxamide derivati...)
Affinity DataIC50:  4.11E+4nMpH: 7.0 T: 2°CAssay Description:Stains-all assay were used to test inhibitors at pH of 7.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHyaluronidase-1(Homo sapiens (Human))
TBA

LigandPNGBDBM81862(N-Substituted indole-2- and 3-carboxamide derivati...)
Affinity DataIC50:  2.72E+4nMpH: 7.0 T: 2°CAssay Description:Stains-all assay were used to test inhibitors at pH of 7.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHyaluronidase-1(Homo sapiens (Human))
TBA

LigandPNGBDBM81860(N-Substituted indole-2- and 3-carboxamide derivati...)
Affinity DataIC50:  4.03E+4nMpH: 7.0 T: 2°CAssay Description:Stains-all assay were used to test inhibitors at pH of 7.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHyaluronidase-1(Homo sapiens (Human))
TBA

LigandPNGBDBM81861(N-Substituted indole-2- and 3-carboxamide derivati...)
Affinity DataIC50:  3.32E+4nMpH: 7.0 T: 2°CAssay Description:Stains-all assay were used to test inhibitors at pH of 7.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHyaluronidase-1(Homo sapiens (Human))
TBA

LigandPNGBDBM50316415(CHEMBL1097937 | Cimicifugic acid L | cimicifugic a...)
Affinity DataIC50:  1.02E+5nMAssay Description:Inhibition of hyaluronidaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHyaluronidase-1(Homo sapiens (Human))
TBA

LigandPNGBDBM50316416(CHEMBL1096937 | Cimicifugic acid M)
Affinity DataIC50:  1.73E+5nMAssay Description:Inhibition of hyaluronidaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHyaluronidase-1(Homo sapiens (Human))
TBA

LigandPNGBDBM50316417(CHEMBL1094303 | Cimicifugic acid N)
Affinity DataIC50:  1.20E+5nMAssay Description:Inhibition of hyaluronidaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHyaluronidase-1(Homo sapiens (Human))
TBA

LigandPNGBDBM4375((2E)-3-(3,4-dihydroxyphenyl)prop-2-enoic acid | (2...)
Affinity DataIC50: >2.00E+6nMAssay Description:Inhibition of hyaluronidaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHyaluronidase-1/Hyaluronidase-2(Bos taurus )
Medical University Of Lodz

Curated by ChEMBL
LigandPNGBDBM50292241(CHEMBL4159080)
Affinity DataIC50:  4.66E+5nMAssay Description:Inhibition of bovine testes hyaluronidase using hyaluronic acid as substrate preincubated for 10 mins in dark followed by incubation with substrate f...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHyaluronidase-1(Homo sapiens (Human))
TBA

LigandPNGBDBM50241245((2E)-3-(3-hydroxy-4-methoxyphenyl)prop-2-enoic aci...)
Affinity DataIC50: >2.00E+6nMAssay Description:Inhibition of hyaluronidaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHyaluronidase-1(Homo sapiens (Human))
TBA

LigandPNGBDBM50133496((2R)-3-(3,4-dihydroxyphenyl)-2-[(2E)-3-(3,4-dihydr...)
Affinity DataIC50:  5.45E+5nMAssay Description:Inhibition of hyaluronidaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHyaluronidase-1(Homo sapiens (Human))
TBA

LigandPNGBDBM50316414(CHEMBL1096631 | Cimicifugic acid K)
Affinity DataIC50:  2.55E+5nMAssay Description:Inhibition of hyaluronidaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHyaluronidase-1(Homo sapiens (Human))
TBA

LigandPNGBDBM50214744((2E)-3-(4-hydroxy-3-methoxyphenyl)prop-2-enoic aci...)
Affinity DataIC50: >2.00E+6nMAssay Description:Inhibition of hyaluronidaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed