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Found 417 Enz. Inhib. hit(s) with Target = 'Lysine-specific demethylase 6B'
TargetLysine-specific demethylase 6B(Homo sapiens (Human))
University Of Oxford

LigandPNGBDBM26106(CHEMBL90852 | N-oxalyl glycine, 1a | NOG | Oxalylg...)
Affinity DataIC50:  680nMpH: 7.5Assay Description:The demethylase AlphaScreen assay was performed in 384-well plate format using white proxiplates (PerkinElmer), and transfer of compound (100 nl) was...More data for this Ligand-Target Pair
TargetLysine-specific demethylase 6B(Homo sapiens (Human))
University Of Oxford

LigandPNGBDBM26113(2,4 PDCA | cid_10365 | pyridine carboxylate, 6a | ...)
Affinity DataIC50:  4.20E+4nMpH: 7.5Assay Description:The demethylase AlphaScreen assay was performed in 384-well plate format using white proxiplates (PerkinElmer), and transfer of compound (100 nl) was...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysine-specific demethylase 6B(Homo sapiens (Human))
University Of Oxford

LigandPNGBDBM191598(2-(((2-((2-(dimethylamino)ethyl)(ethyl)amino)-2-ox...)
Affinity DataIC50:  1.40E+3nMpH: 7.5Assay Description:The demethylase AlphaScreen assay was performed in 384-well plate format using white proxiplates (PerkinElmer), and transfer of compound (100 nl) was...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysine-specific demethylase 6B(Homo sapiens (Human))
University Of Oxford

LigandPNGBDBM60875(3-((6-(4,5-Dihydro-1H-benzo[d]azepin-3(2H)-yl)-2-(...)
Affinity DataIC50:  160nMpH: 7.5Assay Description:The demethylase AlphaScreen assay was performed in 384-well plate format using white proxiplates (PerkinElmer), and transfer of compound (100 nl) was...More data for this Ligand-Target Pair
TargetLysine-specific demethylase 6B(Homo sapiens (Human))
University Of Oxford

LigandPNGBDBM231631(Biotin-KAPRKQLATKAARKMe3SAPATGG | H3K27Me3 peptide)
Affinity DataKd:  800nMpH: 7.5 T: 2°CAssay Description:Binding assays were carried out as 20-μl reactions in 384-well white ProxiPlates (Perkin-Elmer Life Sciences) as described [Hong et al., Proc. N...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetLysine-specific demethylase 6B(Homo sapiens (Human))
University Of Oxford

LigandPNGBDBM50594969(CHEMBL4218391)
Affinity DataKi:  7.11E+3nMAssay Description:Binding affinity to KDM6B (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetLysine-specific demethylase 6B(Homo sapiens (Human))
University Of Oxford

LigandPNGBDBM50594970(CHEMBL5196038)
Affinity DataKi:  7.46E+3nMAssay Description:Binding affinity to KDM6B (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetLysine-specific demethylase 6B(Homo sapiens (Human))
University Of Oxford

LigandPNGBDBM223317(KDOAM-1)
Affinity DataIC50: <1.00E+5nMAssay Description:We previously described 4-carboxy-2-triazolopyridines as selective KDM2 inhibitors (England et al., 2014). In efforts to find alternative scaffolds b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLysine-specific demethylase 6B(Homo sapiens (Human))
University Of Oxford

LigandPNGBDBM191598(2-(((2-((2-(dimethylamino)ethyl)(ethyl)amino)-2-ox...)
Affinity DataIC50:  1.00E+3nMAssay Description:We previously described 4-carboxy-2-triazolopyridines as selective KDM2 inhibitors (England et al., 2014). In efforts to find alternative scaffolds b...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysine-specific demethylase 6B(Homo sapiens (Human))
University Of Oxford

LigandPNGBDBM191599(KDOAM-21 | ethyl 2-(((2-((2-(dimethylamino)ethyl)(...)
Affinity DataIC50:  1.00E+4nMAssay Description:We previously described 4-carboxy-2-triazolopyridines as selective KDM2 inhibitors (England et al., 2014). In efforts to find alternative scaffolds b...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysine-specific demethylase 6B(Homo sapiens (Human))
University Of Oxford

LigandPNGBDBM223318(KDOAM-28)
Affinity DataIC50:  8.00E+3nMAssay Description:We previously described 4-carboxy-2-triazolopyridines as selective KDM2 inhibitors (England et al., 2014). In efforts to find alternative scaffolds b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLysine-specific demethylase 6B(Homo sapiens (Human))
University Of Oxford

LigandPNGBDBM223320(KDOAM-25)
Affinity DataIC50:  1.00E+5nMAssay Description:We previously described 4-carboxy-2-triazolopyridines as selective KDM2 inhibitors (England et al., 2014). In efforts to find alternative scaffolds b...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysine-specific demethylase 6B(Homo sapiens (Human))
University Of Oxford

LigandPNGBDBM50140344(CHEMBL3753122)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of JMJD3 (unknown origin) using biotinylated H3K27me3 peptide as substrate after 1 hr by AlphaLISA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysine-specific demethylase 6B(Homo sapiens (Human))
University Of Oxford

LigandPNGBDBM50140345(CHEMBL3752179)
Affinity DataIC50:  210nMAssay Description:Inhibition of JMJD3 (unknown origin) using biotinylated H3K27me3 peptide as substrate after 1 hr by AlphaLISA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysine-specific demethylase 6B(Homo sapiens (Human))
University Of Oxford

LigandPNGBDBM50140346(CHEMBL3752006)
Affinity DataIC50:  2.10E+3nMAssay Description:Inhibition of JMJD3 (unknown origin) using biotinylated H3K27me3 peptide as substrate after 1 hr by AlphaLISA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysine-specific demethylase 6B(Homo sapiens (Human))
University Of Oxford

LigandPNGBDBM50140347(CHEMBL3753356)
Affinity DataIC50:  1.40E+3nMAssay Description:Inhibition of JMJD3 (unknown origin) using biotinylated H3K27me3 peptide as substrate after 1 hr by AlphaLISA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysine-specific demethylase 6B(Homo sapiens (Human))
University Of Oxford

LigandPNGBDBM50140348(CHEMBL3754052)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of JMJD3 (unknown origin) using biotinylated H3K27me3 peptide as substrate after 1 hr by AlphaLISA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysine-specific demethylase 6B(Homo sapiens (Human))
University Of Oxford

LigandPNGBDBM50140349(CHEMBL3754555)
Affinity DataIC50:  2.20E+3nMAssay Description:Inhibition of JMJD3 (unknown origin) using biotinylated H3K27me3 peptide as substrate after 1 hr by AlphaLISA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysine-specific demethylase 6B(Homo sapiens (Human))
University Of Oxford

LigandPNGBDBM50140350(CHEMBL3754777)
Affinity DataIC50:  5.80E+3nMAssay Description:Inhibition of JMJD3 (unknown origin) using biotinylated H3K27me3 peptide as substrate after 1 hr by AlphaLISA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysine-specific demethylase 6B(Homo sapiens (Human))
University Of Oxford

LigandPNGBDBM50140351(CHEMBL3752471)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of JMJD3 (unknown origin) using biotinylated H3K27me3 peptide as substrate after 1 hr by AlphaLISA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysine-specific demethylase 6B(Homo sapiens (Human))
University Of Oxford

LigandPNGBDBM50140566(CHEMBL3754383)
Affinity DataIC50:  6.10E+3nMAssay Description:Inhibition of JMJD3 (unknown origin) using biotinylated H3K27me3 peptide as substrate after 1 hr by AlphaLISA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysine-specific demethylase 6B(Homo sapiens (Human))
University Of Oxford

LigandPNGBDBM60875(3-((6-(4,5-Dihydro-1H-benzo[d]azepin-3(2H)-yl)-2-(...)
Affinity DataIC50:  150nMAssay Description:Inhibition of JMJD3 (unknown origin) using biotinylated H3K27me3 peptide as substrate after 1 hr by AlphaLISA assayMore data for this Ligand-Target Pair
TargetLysine-specific demethylase 6B(Homo sapiens (Human))
University Of Oxford

LigandPNGBDBM50140567(CHEMBL3752893)
Affinity DataIC50:  200nMAssay Description:Inhibition of JMJD3 (unknown origin) using biotinylated H3K27me3 peptide as substrate after 1 hr by AlphaLISA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysine-specific demethylase 6B(Homo sapiens (Human))
University Of Oxford

LigandPNGBDBM50140568(CHEMBL3754078)
Affinity DataIC50:  1.20E+3nMAssay Description:Inhibition of JMJD3 (unknown origin) using biotinylated H3K27me3 peptide as substrate after 1 hr by AlphaLISA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysine-specific demethylase 6B(Homo sapiens (Human))
University Of Oxford

LigandPNGBDBM50140569(CHEMBL3752995)
Affinity DataIC50:  2.10E+3nMAssay Description:Inhibition of JMJD3 (unknown origin) using biotinylated H3K27me3 peptide as substrate after 1 hr by AlphaLISA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysine-specific demethylase 6B(Homo sapiens (Human))
University Of Oxford

LigandPNGBDBM50140570(CHEMBL3752143)
Affinity DataIC50:  600nMAssay Description:Inhibition of JMJD3 (unknown origin) using biotinylated H3K27me3 peptide as substrate after 1 hr by AlphaLISA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysine-specific demethylase 6B(Homo sapiens (Human))
University Of Oxford

LigandPNGBDBM50140571(CHEMBL3752294)
Affinity DataIC50:  900nMAssay Description:Inhibition of JMJD3 (unknown origin) using biotinylated H3K27me3 peptide as substrate after 1 hr by AlphaLISA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysine-specific demethylase 6B(Homo sapiens (Human))
University Of Oxford

LigandPNGBDBM50140572(CHEMBL3753199)
Affinity DataIC50:  990nMAssay Description:Inhibition of JMJD3 (unknown origin) using biotinylated H3K27me3 peptide as substrate after 1 hr by AlphaLISA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysine-specific demethylase 6B(Homo sapiens (Human))
University Of Oxford

LigandPNGBDBM50140573(CHEMBL3752343)
Affinity DataIC50:  940nMAssay Description:Inhibition of JMJD3 (unknown origin) using biotinylated H3K27me3 peptide as substrate after 1 hr by AlphaLISA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysine-specific demethylase 6B(Homo sapiens (Human))
University Of Oxford

LigandPNGBDBM50140574(CHEMBL3753391)
Affinity DataIC50:  150nMAssay Description:Inhibition of JMJD3 (unknown origin) using biotinylated H3K27me3 peptide as substrate after 1 hr by AlphaLISA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysine-specific demethylase 6B(Homo sapiens (Human))
University Of Oxford

LigandPNGBDBM50140575(CHEMBL3753449)
Affinity DataIC50:  750nMAssay Description:Inhibition of JMJD3 (unknown origin) using biotinylated H3K27me3 peptide as substrate after 1 hr by AlphaLISA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysine-specific demethylase 6B(Homo sapiens (Human))
University Of Oxford

LigandPNGBDBM50140576(CHEMBL3752835)
Affinity DataIC50:  550nMAssay Description:Inhibition of JMJD3 (unknown origin) using biotinylated H3K27me3 peptide as substrate after 1 hr by AlphaLISA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysine-specific demethylase 6B(Homo sapiens (Human))
University Of Oxford

LigandPNGBDBM50140577(CHEMBL3753326)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of JMJD3 (unknown origin) using biotinylated H3K27me3 peptide as substrate after 1 hr by AlphaLISA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysine-specific demethylase 6B(Homo sapiens (Human))
University Of Oxford

LigandPNGBDBM50140677(CHEMBL3752551)
Affinity DataIC50:  740nMAssay Description:Inhibition of JMJD3 (unknown origin) using biotinylated H3K27me3 peptide as substrate after 1 hr by AlphaLISA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysine-specific demethylase 6B(Homo sapiens (Human))
University Of Oxford

LigandPNGBDBM50140678(CHEMBL3752769)
Affinity DataIC50:  490nMAssay Description:Inhibition of JMJD3 (unknown origin) using biotinylated H3K27me3 peptide as substrate after 1 hr by AlphaLISA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysine-specific demethylase 6B(Homo sapiens (Human))
University Of Oxford

LigandPNGBDBM50140679(CHEMBL3752327)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of JMJD3 (unknown origin) using biotinylated H3K27me3 peptide as substrate after 1 hr by AlphaLISA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysine-specific demethylase 6B(Homo sapiens (Human))
University Of Oxford

LigandPNGBDBM50140680(CHEMBL3753740)
Affinity DataIC50:  270nMAssay Description:Inhibition of JMJD3 (unknown origin) using biotinylated H3K27me3 peptide as substrate after 1 hr by AlphaLISA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysine-specific demethylase 6B(Homo sapiens (Human))
University Of Oxford

LigandPNGBDBM50140681(CHEMBL3753787)
Affinity DataIC50:  1.50E+3nMAssay Description:Inhibition of JMJD3 (unknown origin) using biotinylated H3K27me3 peptide as substrate after 1 hr by AlphaLISA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysine-specific demethylase 6B(Homo sapiens (Human))
University Of Oxford

LigandPNGBDBM50140682(CHEMBL3752967)
Affinity DataIC50:  1.30E+3nMAssay Description:Inhibition of JMJD3 (unknown origin) using biotinylated H3K27me3 peptide as substrate after 1 hr by AlphaLISA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysine-specific demethylase 6B(Homo sapiens (Human))
University Of Oxford

LigandPNGBDBM50140683(CHEMBL3752156)
Affinity DataIC50:  1.40E+3nMAssay Description:Inhibition of JMJD3 (unknown origin) using biotinylated H3K27me3 peptide as substrate after 1 hr by AlphaLISA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysine-specific demethylase 6B(Homo sapiens (Human))
University Of Oxford

LigandPNGBDBM50140684(CHEMBL3753893)
Affinity DataIC50:  1.20E+3nMAssay Description:Inhibition of JMJD3 (unknown origin) using biotinylated H3K27me3 peptide as substrate after 1 hr by AlphaLISA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysine-specific demethylase 6B(Homo sapiens (Human))
University Of Oxford

LigandPNGBDBM50140685(CHEMBL3753303)
Affinity DataIC50:  2.60E+3nMAssay Description:Inhibition of JMJD3 (unknown origin) using biotinylated H3K27me3 peptide as substrate after 1 hr by AlphaLISA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysine-specific demethylase 6B(Homo sapiens (Human))
University Of Oxford

LigandPNGBDBM195612(GSK467)
Affinity DataIC50: <1.00E+5nMAssay Description:Inhibition of KDM6B (unknown origin) by RFMS assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysine-specific demethylase 6B(Homo sapiens (Human))
University Of Oxford

LigandPNGBDBM50149911(CHEMBL3770732)
Affinity DataIC50: <1.00E+5nMAssay Description:Inhibition of KDM6B (unknown origin) by RFMS assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysine-specific demethylase 6B(Homo sapiens (Human))
University Of Oxford

LigandPNGBDBM50122002(CHEMBL1383671)
Affinity DataIC50:  6.31E+4nMAssay Description:Inhibition of KDM6B (unknown origin) by RFMS assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysine-specific demethylase 6B(Homo sapiens (Human))
University Of Oxford

LigandPNGBDBM50149925(CHEMBL3770740)
Affinity DataIC50: <1.00E+5nMAssay Description:Inhibition of KDM6B (unknown origin) by RFMS assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysine-specific demethylase 6B(Homo sapiens (Human))
University Of Oxford

LigandPNGBDBM50149920(CHEMBL3769724)
Affinity DataIC50: <1.00E+5nMAssay Description:Inhibition of KDM6B (unknown origin) by RFMS assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysine-specific demethylase 6B(Homo sapiens (Human))
University Of Oxford

LigandPNGBDBM50149917(CHEMBL3771198)
Affinity DataIC50: <1.00E+5nMAssay Description:Inhibition of KDM6B (unknown origin) by RFMS assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysine-specific demethylase 6B(Homo sapiens (Human))
University Of Oxford

LigandPNGBDBM26113(2,4 PDCA | cid_10365 | pyridine carboxylate, 6a | ...)
Affinity DataIC50:  4.46E+4nMAssay Description:Inhibition of KDM6B (unknown origin) expressed in Escherichia coli using H3 (21 to 44 residues) K27Me3-GGK-Biotin JMJD3 Cognate Ligand/10 uM alpha-ke...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysine-specific demethylase 6B(Homo sapiens (Human))
University Of Oxford

LigandPNGBDBM50151392(CHEMBL3775262)
Affinity DataIC50:  2.70E+4nMAssay Description:Inhibition of KDM6B (unknown origin) expressed in Escherichia coli using H3 (21 to 44 residues) K27Me3-GGK-Biotin JMJD3 Cognate Ligand/10 uM alpha-ke...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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