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Found 151 Enz. Inhib. hit(s) with Target = 'Squalene monooxygenase'
TargetSqualene monooxygenase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50286538(6,11,15,19-tetramethyl-2-(4-methyl-3-pentenyl)-(2Z...)
Affinity DataIC50:  1.09E+5nMpH: 7.4Assay Description:The compound was tested for its inhibitory activity against pig Squalene epoxidase at pH 7.4More data for this Ligand-Target Pair
In DepthDetails Article
TargetSqualene monooxygenase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50286540(1N-[20-(6-aminohexylamino)-4,8,13,17-tetramethyl-(...)
Affinity DataKi:  2.40E+3nMpH: 8.8Assay Description:The compound was tested for its inhibitory activity against pig Squalene epoxidase at pH 7.4More data for this Ligand-Target Pair
In DepthDetails Article
TargetSqualene monooxygenase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50286538(6,11,15,19-tetramethyl-2-(4-methyl-3-pentenyl)-(2Z...)
Affinity DataIC50:  3.20E+4nMpH: 8.8Assay Description:The compound was tested for its inhibitory activity against pig Squalene epoxidase at pH 8.8More data for this Ligand-Target Pair
In DepthDetails Article
TargetSqualene monooxygenase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50018518(((E)-6,6-Dimethyl-hept-2-en-4-ynyl)-methyl-naphtha...)
Affinity DataKi:  30nMAssay Description:Apparent inhibitory constant of the compound against squalene epoxidaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetSqualene monooxygenase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50279929((2Z,6E,10E,14E)-6,11,15,19-Tetramethyl-2-(4-methyl...)
Affinity DataKi:  4.00E+3nMAssay Description:Inhibitory activity of the compound was measured against partially purified pig liver Squalene epoxidase (SE).More data for this Ligand-Target Pair
In DepthDetails Article
TargetSqualene monooxygenase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50018524(6,10,15,19,23-Pentamethyl-tetracosa-6,10,14,18,22-...)
Affinity DataKi:  9.50E+5nMAssay Description:Apparent inhibitory constant of the compound against squalene epoxidaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene monooxygenase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50018522(6,10,15,19-Tetramethyl-tetracosa-6,10,14,18-tetrae...)
Affinity DataKi:  1.00E+6nMAssay Description:Inhibitory activity against Candida albicans Squalene EpoxidaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene monooxygenase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50281969((1E,5E,9E,13E,17E)-5,9,14,18,22-Pentamethyl-1-nitr...)
Affinity DataIC50: >4.00E+5nMAssay Description:Inhibitory concentration of the compound at which 50% decrease in the activity of Squalene epoxidase in pig liver microsomesMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSqualene monooxygenase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50281970((9E,13E,21E)-5,9,14,18,22-Pentamethyl-1-nitro-tric...)
Affinity DataIC50:  2.70E+5nMAssay Description:Inhibitory concentration of the compound at which 50% decrease in the activity of Squalene epoxidase in pig liver microsomesMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSqualene monooxygenase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50281968(CHEMBL9533 | N-Methyl-N-((4E,12E,16E,20E)-4,8,13,1...)
Affinity DataIC50:  1.30E+4nMAssay Description:Inhibitory concentration of the compound at which 50% decrease in the activity of Squalene epoxidase in pig liver microsomesMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSqualene monooxygenase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50291662(CHEMBL15811 | [3-(2-Azido-phenyl)-prop-2-ynyl]-[3-...)
Affinity DataIC50: >1.00E+5nMAssay Description:In vitro inhibition of pig liver microsomal squalene epoxidase (SE) by measuring the extend of cholesterol radiolabeling after incubation with [14C]-...More data for this Ligand-Target Pair
In DepthDetails Article
TargetSqualene monooxygenase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50291658((3-{[(4-Azido-phenyl)-dimethyl-silanyl]-methoxy}-b...)
Affinity DataIC50:  520nMAssay Description:In vitro inhibition of pig liver microsomal squalene epoxidase (SE) by measuring the extend of cholesterol radiolabeling after incubation with [14C]-...More data for this Ligand-Target Pair
In DepthDetails Article
TargetSqualene monooxygenase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50291660(CHEMBL16178 | [3-([3,3']Bithiophenyl-5-ylmethoxy)-...)
Affinity DataIC50:  100nMAssay Description:In vitro inhibition of pig liver microsomal squalene epoxidase (SE) by measuring the extend of cholesterol radiolabeling after incubation with [14C]-...More data for this Ligand-Target Pair
In DepthDetails Article
TargetSqualene monooxygenase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50032836(4-[(3-{[((E)-6,6-Dimethyl-hept-2-en-4-ynyl)-ethyl-...)
Affinity DataIC50:  20nMAssay Description:In vitro inhibition of pig liver microsomal squalene epoxidase (SE) by measuring the extend of cholesterol radiolabeling after incubation with [14C]-...More data for this Ligand-Target Pair
In DepthDetails Article
TargetSqualene monooxygenase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50291659(CHEMBL16120 | [3-(4-Azido-phenyl)-prop-2-ynyl]-[3-...)
Affinity DataIC50:  960nMAssay Description:In vitro inhibition of pig liver microsomal squalene epoxidase (SE) by measuring the extend of cholesterol radiolabeling after incubation with [14C]-...More data for this Ligand-Target Pair
In DepthDetails Article
TargetSqualene monooxygenase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50291661(CHEMBL267332 | [3-(3-Azido-phenyl)-prop-2-ynyl]-[3...)
Affinity DataIC50:  270nMAssay Description:In vitro inhibition of pig liver microsomal squalene epoxidase (SE) by measuring the extend of cholesterol radiolabeling after incubation with [14C]-...More data for this Ligand-Target Pair
In DepthDetails Article
TargetSqualene monooxygenase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50070350(CHEMBL284197 | N-[2-(3-{[((E)-6,6-Dimethyl-hept-2-...)
Affinity DataIC50:  200nMAssay Description:In vitro inhibition of cholesterol biosynthesis in human HepG2 cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene monooxygenase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50070331(4-Cyano-N-[2-(3-{[((E)-6,6-dimethyl-hept-2-en-4-yn...)
Affinity DataIC50:  200nMAssay Description:In vitro inhibition of cholesterol biosynthesis in human HepG2 cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene monooxygenase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50070349(CHEMBL26597 | Thiophene-3-sulfonic acid [2-(3-{[((...)
Affinity DataIC50:  250nMAssay Description:In vitro inhibition of cholesterol biosynthesis in human HepG2 cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene monooxygenase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50070347(4-Bromo-N-[2-(3-{[((E)-6,6-dimethyl-hept-2-en-4-yn...)
Affinity DataIC50:  330nMAssay Description:In vitro inhibition of cholesterol biosynthesis in human HepG2 cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene monooxygenase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50070336(CHEMBL26082 | Thiophene-2-sulfonic acid [3-(3-{[((...)
Affinity DataIC50:  6.40E+3nMAssay Description:In vitro inhibition of cholesterol biosynthesis in human HepG2 cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene monooxygenase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50070339(4-Bromo-thiophene-2-sulfonic acid [2-(3-{[((E)-6,6...)
Affinity DataIC50:  300nMAssay Description:In vitro inhibition of cholesterol biosynthesis in human HepG2 cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene monooxygenase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50070333(CHEMBL281666 | N-[2-(3-{[((E)-6,6-Dimethyl-hept-2-...)
Affinity DataIC50:  255nMAssay Description:In vitro inhibition of cholesterol biosynthesis in human HepG2 cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene monooxygenase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50070340(CHEMBL281025 | Thiophene-2-sulfonic acid [2-(3-{[(...)
Affinity DataIC50:  50nMAssay Description:Compound was evaluated in vitro for the inhibition of pig liver squalene epoxidase in HepG2 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene monooxygenase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50070332(CHEMBL27195 | [2,2']Bithiophenyl-5-sulfonic acid [...)
Affinity DataIC50:  1.00E+4nMAssay Description:In vitro inhibition of cholesterol biosynthesis in human HepG2 cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene monooxygenase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50070335(CHEMBL280972 | Thiophene-2-sulfonic acid [2-(3-{[(...)
Affinity DataIC50:  450nMAssay Description:In vitro inhibition of cholesterol biosynthesis in human HepG2 cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene monooxygenase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50070348(((E)-6,6-Dimethyl-hept-2-en-4-ynyl)-ethyl-{3-[3-(t...)
Affinity DataIC50:  290nMAssay Description:In vitro inhibition of cholesterol biosynthesis in human HepG2 cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene monooxygenase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50070342(CHEMBL26077 | Thiophene-2-sulfonic acid cyclopropy...)
Affinity DataIC50:  230nMAssay Description:In vitro inhibition of cholesterol biosynthesis in human HepG2 cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene monooxygenase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50070345(CHEMBL26964 | Thiophene-2-sulfonic acid [2-(3-{[((...)
Affinity DataIC50:  170nMAssay Description:In vitro inhibition of cholesterol biosynthesis in human HepG2 cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene monooxygenase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50070338(5-Bromo-thiophene-2-sulfonic acid [2-(3-{[((E)-6,6...)
Affinity DataIC50:  390nMAssay Description:In vitro inhibition of cholesterol biosynthesis in human HepG2 cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene monooxygenase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50070346(CHEMBL27941 | [2,3']Bithiophenyl-5-sulfonic acid [...)
Affinity DataIC50:  210nMAssay Description:In vitro inhibition of cholesterol biosynthesis in human HepG2 cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene monooxygenase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50070337(CHEMBL27154 | [3,3']Bithiophenyl-5-sulfonic acid [...)
Affinity DataIC50:  90nMAssay Description:In vitro inhibition of cholesterol biosynthesis in human HepG2 cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene monooxygenase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50070334(Benzo[b]thiophene-2-sulfonic acid [2-(3-{[((E)-6,6...)
Affinity DataIC50:  1.80E+3nMAssay Description:In vitro inhibition of cholesterol biosynthesis in human HepG2 cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene monooxygenase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50070341(CHEMBL26151 | Pyridine-3-sulfonic acid [2-(3-{[((E...)
Affinity DataIC50:  150nMAssay Description:In vitro inhibition of cholesterol biosynthesis in human HepG2 cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene monooxygenase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50070344(CHEMBL26950 | Thiophene-2-sulfonic acid [2-(3-{[((...)
Affinity DataIC50:  90nMAssay Description:In vitro inhibition of cholesterol biosynthesis in human HepG2 cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene monooxygenase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50070343(CHEMBL26596 | Thiazole-2-sulfonic acid [2-(3-{[((E...)
Affinity DataIC50:  170nMAssay Description:In vitro inhibition of cholesterol biosynthesis in human HepG2 cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene monooxygenase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50283103(3-{[3-([2,3']Bithiophenyl-5'-ylmethoxy)-benzyl]-et...)
Affinity DataIC50:  5.00E+5nMAssay Description:Compound was tested for inhibition of partially purified squalene epoxidaseMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSqualene monooxygenase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50283106((4-{[3-([2,3']Bithiophenyl-5'-ylmethoxy)-benzyl]-e...)
Affinity DataIC50:  5.00E+5nMAssay Description:Compound was tested for inhibition of partially purified squalene epoxidaseMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSqualene monooxygenase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50283104(CHEMBL304796 | [3-(3-{[((E)-6,6-Dimethyl-hept-2-en...)
Affinity DataIC50:  5.00E+5nMAssay Description:Compound was tested for inhibition of partially purified squalene epoxidaseMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSqualene monooxygenase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50283105(2-{[3-([2,3']Bithiophenyl-5'-ylmethoxy)-benzyl]-et...)
Affinity DataIC50:  5.00E+5nMAssay Description:Compound was tested for inhibition of partially purified squalene epoxidaseMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSqualene monooxygenase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50288841((3-{[((E)-6,6-Dimethyl-hept-2-en-4-ynyl)-ethyl-ami...)
Affinity DataIC50:  100nMAssay Description:Compound was evaluated for the inhibition of pig liver microsomal squalene epoxidase.More data for this Ligand-Target Pair
In DepthDetails Article
TargetSqualene monooxygenase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50032843(((E)-6,6-Dimethyl-hept-2-en-4-ynyl)-{3-[(dimethyl-...)
Affinity DataIC50:  30nMAssay Description:Compound was evaluated for the inhibition of pig liver microsomal squalene epoxidase.More data for this Ligand-Target Pair
In DepthDetails Article
TargetSqualene monooxygenase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50015503(5,9,14,18,22-Pentamethyl-tricosa-5,9,13,17,21-pent...)
Affinity DataIC50:  4.00E+3nMAssay Description:Inhibition of pig liver squalene epoxidaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene monooxygenase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50015505(4,9,13,17-Tetramethyl-octadeca-4,8,12,16-tetraen-1...)
Affinity DataIC50:  1.00E+5nMAssay Description:Inhibition of pig liver squalene epoxidaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene monooxygenase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50015507(4,8,13,17,21-Pentamethyl-docosa-4,8,12,16,20-penta...)
Affinity DataIC50:  4.00E+3nMAssay Description:Inhibition of pig liver squalene epoxidaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene monooxygenase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50015504(5,9,13-Trimethyl-tetradeca-4,8,12-trien-1-ol | CHE...)
Affinity DataIC50: >4.00E+5nMAssay Description:Inhibition of pig liver squalene epoxidaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene monooxygenase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50015508(3,7,12,16,20-Pentamethyl-henicosa-3,7,11,15,19-pen...)
Affinity DataIC50:  4.00E+4nMAssay Description:Inhibition of pig liver squalene epoxidaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene monooxygenase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50015506(4,8,12,17,21,25-Hexamethyl-hexacosa-4,8,12,16,20,2...)
Affinity DataIC50: >4.00E+5nMAssay Description:Inhibition of pig liver squalene epoxidaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene monooxygenase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50018516((1,5,9,14,18,22-Hexamethyl-tricosa-1,5,9,13,17,21-...)
Affinity DataIC50: >4.00E+5nMAssay Description:Inhibitory activity against Squalene Epoxidase in pig liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene monooxygenase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50018518(((E)-6,6-Dimethyl-hept-2-en-4-ynyl)-methyl-naphtha...)
Affinity DataIC50:  6.00E+3nMAssay Description:Inhibitory activity against guinea pig Squalene EpoxidaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

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