TargetcAMP-specific 3',5'-cyclic phosphodiesterase 7B(Homo sapiens (Human))
Boehringer Ingehleim International
US Patent
Boehringer Ingehleim International
US Patent
Affinity DataIC50: >4.00E+3nMpH: 7.5Assay Description:The test substances are dissolved in 100% DMSO and serially diluted to determine their in vitro effect on PDE 9A. Typically, serial dilutions from 20...More data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 7B(Homo sapiens (Human))
Boehringer Ingehleim International
US Patent
Boehringer Ingehleim International
US Patent
Affinity DataIC50: >4.00E+3nMpH: 7.5Assay Description:The test substances are dissolved in 100% DMSO and serially diluted to determine their in vitro effect on PDE 9A. 2 uL portions of the diluted substa...More data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 7B(Homo sapiens (Human))
Boehringer Ingehleim International
US Patent
Boehringer Ingehleim International
US Patent
Affinity DataIC50: 106nMpH: 8.0Assay Description:The assay method used was a scintillation proximity assay (SPA) (obtained from GE Healthcare, Product Code TRKQ7100), with [3H]-cGMP as the substrate...More data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 7B(Homo sapiens (Human))
Boehringer Ingehleim International
US Patent
Boehringer Ingehleim International
US Patent
Affinity DataIC50: 144nMpH: 8.0Assay Description:The assay method used was a scintillation proximity assay (SPA) (obtained from GE Healthcare, Product Code TRKQ7100), with [3H]-cGMP as the substrate...More data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 7B(Homo sapiens (Human))
Boehringer Ingehleim International
US Patent
Boehringer Ingehleim International
US Patent
Affinity DataIC50: 4.80nMpH: 8.0Assay Description:The assay method used was a scintillation proximity assay (SPA) (obtained from GE Healthcare, Product Code TRKQ7100), with [3H]-cGMP as the substrate...More data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 7B(Homo sapiens (Human))
Boehringer Ingehleim International
US Patent
Boehringer Ingehleim International
US Patent
Affinity DataIC50: 9.27nMpH: 8.0Assay Description:The assay method used was a scintillation proximity assay (SPA) (obtained from GE Healthcare, Product Code TRKQ7100), with [3H]-cGMP as the substrate...More data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 7B(Homo sapiens (Human))
Boehringer Ingehleim International
US Patent
Boehringer Ingehleim International
US Patent
Affinity DataKi: 300nMAssay Description:Inhibition of recombinant full lenght human PDE7B using fluorescent labeled cAMP as substrate after 15 mins by IMAP assayMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 7B(Homo sapiens (Human))
Boehringer Ingehleim International
US Patent
Boehringer Ingehleim International
US Patent
Affinity DataKi: 360nMAssay Description:Inhibition of recombinant full lenght human PDE7B using fluorescent labeled cAMP as substrate after 15 mins by IMAP assayMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 7B(Homo sapiens (Human))
Boehringer Ingehleim International
US Patent
Boehringer Ingehleim International
US Patent
Affinity DataKi: 910nMAssay Description:Inhibition of recombinant full lenght human PDE7B using fluorescent labeled cAMP as substrate after 15 mins by IMAP assayMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 7B(Homo sapiens (Human))
Boehringer Ingehleim International
US Patent
Boehringer Ingehleim International
US Patent
Affinity DataKi: 1.20E+3nMAssay Description:Inhibition of recombinant full lenght human PDE7B using fluorescent labeled cAMP as substrate after 15 mins by IMAP assayMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 7B(Homo sapiens (Human))
Boehringer Ingehleim International
US Patent
Boehringer Ingehleim International
US Patent
Affinity DataKi: 6.10E+3nMAssay Description:Inhibition of recombinant full lenght human PDE7B using fluorescent labeled cAMP as substrate after 15 mins by IMAP assayMore data for this Ligand-Target Pair
Affinity DataIC50: >2.00E+5nMAssay Description:Phosphodiesterase activities were assayed in the presence of inhibitor compounds. Measurement takes advantage of the selective binding of 5-AMP or 5-...More data for this Ligand-Target Pair
Affinity DataIC50: >2.00E+5nMAssay Description:Phosphodiesterase activities were assayed in the presence of inhibitor compounds. Measurement takes advantage of the selective binding of 5-AMP or 5-...More data for this Ligand-Target Pair
Affinity DataIC50: 990nMAssay Description:Phosphodiesterase activities were assayed in the presence of inhibitor compounds. Measurement takes advantage of the selective binding of 5-AMP or 5-...More data for this Ligand-Target Pair
Affinity DataIC50: >2.00E+5nMAssay Description:Phosphodiesterase activities were assayed in the presence of inhibitor compounds. Measurement takes advantage of the selective binding of 5-AMP or 5-...More data for this Ligand-Target Pair
Affinity DataIC50: >2.00E+5nMAssay Description:Phosphodiesterase activities were assayed in the presence of inhibitor compounds. Measurement takes advantage of the selective binding of 5-AMP or 5-...More data for this Ligand-Target Pair
Affinity DataIC50: 8.80E+3nMAssay Description:Phosphodiesterase activities were assayed in the presence of inhibitor compounds. Measurement takes advantage of the selective binding of 5-AMP or 5-...More data for this Ligand-Target Pair
Affinity DataIC50: 7.80E+4nMAssay Description:Phosphodiesterase activities were assayed in the presence of inhibitor compounds. Measurement takes advantage of the selective binding of 5-AMP or 5-...More data for this Ligand-Target Pair
Affinity DataIC50: 1.90E+3nMAssay Description:Phosphodiesterase activities were assayed in the presence of inhibitor compounds. Measurement takes advantage of the selective binding of 5-AMP or 5-...More data for this Ligand-Target Pair
Affinity DataIC50: 7.40E+4nMAssay Description:Phosphodiesterase activities were assayed in the presence of inhibitor compounds. Measurement takes advantage of the selective binding of 5-AMP or 5-...More data for this Ligand-Target Pair
Affinity DataIC50: 4.40E+4nMAssay Description:Phosphodiesterase activities were assayed in the presence of inhibitor compounds. Measurement takes advantage of the selective binding of 5-AMP or 5-...More data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 7B(Homo sapiens (Human))
Boehringer Ingehleim International
US Patent
Boehringer Ingehleim International
US Patent
Affinity DataIC50: 2.20E+3nMAssay Description:Inhibition of human recombinant PDE7B assessed as inhibition of hydrolysis of [3H]cAMP after 20 mins by scintillation proximity assayMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 7B(Homo sapiens (Human))
Boehringer Ingehleim International
US Patent
Boehringer Ingehleim International
US Patent
Affinity DataIC50: 1.41E+3nMAssay Description:Inhibition of human recombinant PDE7B assessed as inhibition of hydrolysis of [3H]cAMP after 20 mins by scintillation proximity assayMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 7B(Homo sapiens (Human))
Boehringer Ingehleim International
US Patent
Boehringer Ingehleim International
US Patent
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of human recombinant PDE7B assessed as inhibition of hydrolysis of [3H]cAMP after 20 mins by scintillation proximity assayMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 7B(Homo sapiens (Human))
Boehringer Ingehleim International
US Patent
Boehringer Ingehleim International
US Patent
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of human recombinant PDE7B assessed as inhibition of hydrolysis of [3H]cAMP after 20 mins by scintillation proximity assayMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 7B(Homo sapiens (Human))
Boehringer Ingehleim International
US Patent
Boehringer Ingehleim International
US Patent
Affinity DataIC50: 600nMAssay Description:Inhibition of human recombinant PDE7B assessed as inhibition of hydrolysis of [3H]cAMP after 20 mins by scintillation proximity assayMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 7B(Homo sapiens (Human))
Boehringer Ingehleim International
US Patent
Boehringer Ingehleim International
US Patent
Affinity DataIC50: 1.39E+4nMAssay Description:Inhibition of human recombinant PDE7B assessed as inhibition of hydrolysis of [3H]cAMP after 20 mins by scintillation proximity assayMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 7B(Homo sapiens (Human))
Boehringer Ingehleim International
US Patent
Boehringer Ingehleim International
US Patent
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of PDE7bMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 7B(Homo sapiens (Human))
Boehringer Ingehleim International
US Patent
Boehringer Ingehleim International
US Patent
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of PDE7bMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 7B(Homo sapiens (Human))
Boehringer Ingehleim International
US Patent
Boehringer Ingehleim International
US Patent
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of PDE7bMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 7B(Homo sapiens (Human))
Boehringer Ingehleim International
US Patent
Boehringer Ingehleim International
US Patent
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human PDE7BMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 7B(Homo sapiens (Human))
Boehringer Ingehleim International
US Patent
Boehringer Ingehleim International
US Patent
Affinity DataIC50: >2.00E+3nMAssay Description:Inhibition of PDE7BMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 7B(Homo sapiens (Human))
Boehringer Ingehleim International
US Patent
Boehringer Ingehleim International
US Patent
Affinity DataIC50: >2.00E+3nMAssay Description:Inhibition of PDE7BMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 7B(Homo sapiens (Human))
Boehringer Ingehleim International
US Patent
Boehringer Ingehleim International
US Patent
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of PDE7BMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 7B(Homo sapiens (Human))
Boehringer Ingehleim International
US Patent
Boehringer Ingehleim International
US Patent
Affinity DataIC50: >2.00E+3nMAssay Description:Inhibition of PDE7BMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 7B(Homo sapiens (Human))
Boehringer Ingehleim International
US Patent
Boehringer Ingehleim International
US Patent
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of PDE7BMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 7B(Homo sapiens (Human))
Boehringer Ingehleim International
US Patent
Boehringer Ingehleim International
US Patent
Affinity DataIC50: 3.10E+3nMAssay Description:Inhibition of PDE7BMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 7B(Homo sapiens (Human))
Boehringer Ingehleim International
US Patent
Boehringer Ingehleim International
US Patent
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of PDE7BMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 7B(Homo sapiens (Human))
Boehringer Ingehleim International
US Patent
Boehringer Ingehleim International
US Patent
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of PDE7BMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 7B(Homo sapiens (Human))
Boehringer Ingehleim International
US Patent
Boehringer Ingehleim International
US Patent
Affinity DataIC50: >2.00E+3nMAssay Description:Inhibition of PDE7BMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 7B(Homo sapiens (Human))
Boehringer Ingehleim International
US Patent
Boehringer Ingehleim International
US Patent
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of PDE7BMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 7B(Homo sapiens (Human))
Boehringer Ingehleim International
US Patent
Boehringer Ingehleim International
US Patent
Affinity DataIC50: 19nMAssay Description:Inhibition of cloned human recombinant PDE7B assessed as [3H]cAMP hydrolysis by radiometric assayMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 7B(Homo sapiens (Human))
Boehringer Ingehleim International
US Patent
Boehringer Ingehleim International
US Patent
Affinity DataIC50: 11nMAssay Description:Inhibition of cloned human recombinant PDE7B assessed as [3H]cAMP hydrolysis by radiometric assayMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 7B(Homo sapiens (Human))
Boehringer Ingehleim International
US Patent
Boehringer Ingehleim International
US Patent
Affinity DataIC50: 43nMAssay Description:Inhibition of cloned human recombinant PDE7B assessed as [3H]cAMP hydrolysis by radiometric assayMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 7B(Homo sapiens (Human))
Boehringer Ingehleim International
US Patent
Boehringer Ingehleim International
US Patent
Affinity DataIC50: <10nMAssay Description:PDE7 inhibition was determined by an IMAP TR-FRET assay using PDE7B. The IMAP TR-FRET PDE assay was optimized for concentration of enzyme, FAM-cAMP s...More data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 7B(Homo sapiens (Human))
Boehringer Ingehleim International
US Patent
Boehringer Ingehleim International
US Patent
Affinity DataIC50: <10nMAssay Description:PDE7 inhibition was determined by an IMAP TR-FRET assay using PDE7B. The IMAP TR-FRET PDE assay was optimized for concentration of enzyme, FAM-cAMP s...More data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 7B(Homo sapiens (Human))
Boehringer Ingehleim International
US Patent
Boehringer Ingehleim International
US Patent
Affinity DataIC50: <10nMAssay Description:PDE7 inhibition was determined by an IMAP TR-FRET assay using PDE7B. The IMAP TR-FRET PDE assay was optimized for concentration of enzyme, FAM-cAMP s...More data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 7B(Homo sapiens (Human))
Boehringer Ingehleim International
US Patent
Boehringer Ingehleim International
US Patent
Affinity DataIC50: <10nMAssay Description:PDE7 inhibition was determined by an IMAP TR-FRET assay using PDE7B. The IMAP TR-FRET PDE assay was optimized for concentration of enzyme, FAM-cAMP s...More data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 7B(Homo sapiens (Human))
Boehringer Ingehleim International
US Patent
Boehringer Ingehleim International
US Patent
Affinity DataIC50: <10nMAssay Description:PDE7 inhibition was determined by an IMAP TR-FRET assay using PDE7B. The IMAP TR-FRET PDE assay was optimized for concentration of enzyme, FAM-cAMP s...More data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 7B(Homo sapiens (Human))
Boehringer Ingehleim International
US Patent
Boehringer Ingehleim International
US Patent
Affinity DataIC50: <10nMAssay Description:PDE7 inhibition was determined by an IMAP TR-FRET assay using PDE7B. The IMAP TR-FRET PDE assay was optimized for concentration of enzyme, FAM-cAMP s...More data for this Ligand-Target Pair