BindingDB PrimarySearch

Found 12808 hits Enz. Inhib. hit(s) with Target = 'Adenosine receptor A1'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Adenosine receptor A1 (Homo sapiens (Human))	BDBM50493155 (CHEMBL2419148) Show SMILES CCn1c(\N=C\c2ccc(F)cc2)c(sc1=S)C#N Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar	PC cid PC sid UniChem	Article PubMed	0.000590	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Delhi Curated by ChEMBL					Assay Description Displacement of [3H]DPCPX from human A1 receptor expressed in HEK293 cell membranes after 60 mins by scintillation counting				Bioorg Med Chem 21: 6077-83 (2013) Article DOI: 10.1016/j.bmc.2013.07.005 BindingDB Entry DOI: 10.7270/Q2CC13NZ
University of Delhi Curated by ChEMBL					More data for this Ligand-Target Pair
Adenosine receptor A1 (Homo sapiens (Human))	BDBM50493144 (CHEMBL2419144) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar	PC cid PC sid UniChem	Article PubMed	0.000630	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Delhi Curated by ChEMBL					Assay Description Displacement of [3H]DPCPX from human A1 receptor expressed in HEK293 cell membranes after 60 mins by scintillation counting				Bioorg Med Chem 21: 6077-83 (2013) Article DOI: 10.1016/j.bmc.2013.07.005 BindingDB Entry DOI: 10.7270/Q2CC13NZ
University of Delhi Curated by ChEMBL					More data for this Ligand-Target Pair
Adenosine receptor A1 (Homo sapiens (Human))	BDBM50493151 (CHEMBL2419139) Show SMILES CCn1c(\N=C\c2ccc(Br)cc2)c(sc1=S)C#N Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar	PC cid PC sid UniChem	Article PubMed	0.000740	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Delhi Curated by ChEMBL					Assay Description Displacement of [3H]DPCPX from human A1 receptor expressed in HEK293 cell membranes after 60 mins by scintillation counting				Bioorg Med Chem 21: 6077-83 (2013) Article DOI: 10.1016/j.bmc.2013.07.005 BindingDB Entry DOI: 10.7270/Q2CC13NZ
University of Delhi Curated by ChEMBL					More data for this Ligand-Target Pair
Adenosine receptor A1 (Homo sapiens (Human))	BDBM50315544 (8-(2-Thioxo-7(3-p-chlorophenyl.)-2-(2-furyl)thiazo...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.0300	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Delhi Curated by ChEMBL					Assay Description Displacement of [3H]DPCPX from human adenosine A1 receptor expressed in HEK293 cells after 60 mins by rapid filtration assay				Bioorg Med Chem 18: 2491-500 (2010) Article DOI: 10.1016/j.bmc.2010.02.048 BindingDB Entry DOI: 10.7270/Q27W6D57
University of Delhi Curated by ChEMBL					More data for this Ligand-Target Pair
Adenosine receptor A1 (BOVINE)	BDBM50006730 ((R)-2-Hydroxymethyl-5-[6-(1-methyl-2-phenyl-ethyla...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	0.0300	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universität Heidelberg Curated by PDSP K_i Database									Naunyn Schmiedebergs Arch Pharmacol 343: 196-201 (1991) Article DOI: 10.1007/bf00168610 BindingDB Entry DOI: 10.7270/Q22V2DMN
Universität Heidelberg Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Adenosine receptor A1 (BOVINE)	BDBM50207816 (CHEMBL273094 \| N-(2-Amino-ethyl)-2-[4-(2,6-dioxo-1...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar	Purchase CHEMBL MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	0.0300	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universität Heidelberg Curated by PDSP K_i Database									Naunyn Schmiedebergs Arch Pharmacol 343: 196-201 (1991) Article DOI: 10.1007/bf00168610 BindingDB Entry DOI: 10.7270/Q22V2DMN
Universität Heidelberg Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Adenosine receptor A1 (BOVINE)	BDBM21173 (1,3-dipropyl-8-cyclopentylxanthine \| 8-cyclopentyl...) Show SMILES CCCn1c2nc([nH]c2c(=O)n(CCC)c1=O)C1CCCC1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar	Purchase CHEBI CHEMBL KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	0.0500	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universität Heidelberg Curated by PDSP K_i Database									Naunyn Schmiedebergs Arch Pharmacol 343: 196-201 (1991) Article DOI: 10.1007/bf00168610 BindingDB Entry DOI: 10.7270/Q22V2DMN
Universität Heidelberg Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Adenosine receptor A1 (Rattus norvegicus (rat))	BDBM50550819 (CHEMBL4796077) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar	PC cid PC sid UniChem	PubMed	0.0628	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Bonn Curated by ChEMBL					Assay Description Displacement of [3H]DPCPX from rat adenosine receptor A1 by radioligand competition assay				Eur J Med Chem 186: (2020)
University of Bonn Curated by ChEMBL					More data for this Ligand-Target Pair
Adenosine receptor A1 (BOVINE)	BDBM21173 (1,3-dipropyl-8-cyclopentylxanthine \| 8-cyclopentyl...) Show SMILES CCCn1c2nc([nH]c2c(=O)n(CCC)c1=O)C1CCCC1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar	Purchase CHEBI CHEMBL KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	0.0700	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universität Heidelberg Curated by PDSP K_i Database									Naunyn Schmiedebergs Arch Pharmacol 336: 204-10 (1987) Article DOI: 10.1007/bf00165806 BindingDB Entry DOI: 10.7270/Q26H4FXN
Universität Heidelberg Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Adenosine receptor A1 (Rattus norvegicus (rat))	BDBM50550824 (CHEMBL4797181) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar	PC cid PC sid UniChem	PubMed	0.0709	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Bonn Curated by ChEMBL					Assay Description Displacement of [3H]DPCPX from rat adenosine receptor A1 by radioligand competition assay				Eur J Med Chem 186: (2020)
University of Bonn Curated by ChEMBL					More data for this Ligand-Target Pair
Adenosine receptor A1 (BOVINE)	BDBM50207816 (CHEMBL273094 \| N-(2-Amino-ethyl)-2-[4-(2,6-dioxo-1...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar	Purchase CHEMBL MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	0.0800	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universität Heidelberg Curated by PDSP K_i Database									Naunyn Schmiedebergs Arch Pharmacol 336: 204-10 (1987) Article DOI: 10.1007/bf00165806 BindingDB Entry DOI: 10.7270/Q26H4FXN
Universität Heidelberg Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Adenosine receptor A1 (Rattus norvegicus (rat))	BDBM50550832 (CHEMBL4764086) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar	PC cid PC sid UniChem	PubMed	0.0867	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Bonn Curated by ChEMBL					Assay Description Displacement of [3H]DPCPX from rat adenosine receptor A1 by radioligand competition assay				Eur J Med Chem 186: (2020)
University of Bonn Curated by ChEMBL					More data for this Ligand-Target Pair
Adenosine receptor A1 (BOVINE)	BDBM50062858 (8-Cyclopentyl-3-(2-fluoro-propyl)-1-propyl-3,7-dih...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	0.0940	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Forschungszentrum Jülich GmbH Curated by ChEMBL					Assay Description Displacement of [3H]-CPX from Adenosine A1 receptor of bovine brain cerebral cortex membranes				J Med Chem 41: 555-63 (1998) Article DOI: 10.1021/jm9705465 BindingDB Entry DOI: 10.7270/Q2RX9B60
Forschungszentrum Jülich GmbH Curated by ChEMBL					More data for this Ligand-Target Pair
Adenosine receptor A1 (Homo sapiens (Human))	BDBM50315538 (8-(2-Thioxo-7(3-ethyl)-2-(2-furyl)thiazolo[4,3-e]1...) Show SMILES CCn1c2ncn3nc(nc3c2sc1=S)-c1ccco1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.0960	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Delhi Curated by ChEMBL					Assay Description Displacement of [3H]DPCPX from human adenosine A1 receptor expressed in HEK293 cells after 60 mins by rapid filtration assay				Bioorg Med Chem 18: 2491-500 (2010) Article DOI: 10.1016/j.bmc.2010.02.048 BindingDB Entry DOI: 10.7270/Q27W6D57
University of Delhi Curated by ChEMBL					More data for this Ligand-Target Pair
Adenosine receptor A1 (BOVINE)	BDBM50008408 (3-(4-Amino-3-iodo-phenyl)-N-(2-{2-[4-(2,6-dioxo-1,...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
NIDDK Curated by ChEMBL					Assay Description Binding affinity for adenosine A1 receptor using [3H]- CHA or [3H]- PIA in bovine brain cortical membranes				J Med Chem 35: 407-22 (1992) Article DOI: 10.1021/jm00081a001 BindingDB Entry DOI: 10.7270/Q2Z89D1W
NIDDK Curated by ChEMBL					More data for this Ligand-Target Pair
Adenosine receptor A1 (Homo sapiens (Human))	BDBM50493148 (CHEMBL2419137) Show SMILES CCCCn1c(\N=C\c2ccc(Br)cc2)c(sc1=S)C#N Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar	PC cid PC sid UniChem	Article PubMed	0.100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Delhi Curated by ChEMBL					Assay Description Displacement of [3H]DPCPX from human A1 receptor expressed in HEK293 cell membranes after 60 mins by scintillation counting				Bioorg Med Chem 21: 6077-83 (2013) Article DOI: 10.1016/j.bmc.2013.07.005 BindingDB Entry DOI: 10.7270/Q2CC13NZ
University of Delhi Curated by ChEMBL					More data for this Ligand-Target Pair
Adenosine receptor A1 (Rattus norvegicus (rat))	BDBM50550813 (CHEMBL1316674) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar	PC cid PC sid PDB UniChem	PDB PubMed	0.124	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Bonn Curated by ChEMBL					Assay Description Displacement of [3H]CCPA from adenosine receptor A1 in rat brain cortex membranes incubated for 90 mins by radioligand competition assay				Eur J Med Chem 186: (2020)
University of Bonn Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Adenosine receptor A1 (Rattus norvegicus (rat))	BDBM50494549 (CHEMBL3093327) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar	PC cid PC sid UniChem	Article PubMed	0.124	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Bonn Curated by ChEMBL					Assay Description Binding affinity to rat adenosine A1 receptor				Bioorg Med Chem 21: 7435-52 (2013) Article DOI: 10.1016/j.bmc.2013.09.044 BindingDB Entry DOI: 10.7270/Q2TT4TWF
University of Bonn Curated by ChEMBL					More data for this Ligand-Target Pair
Adenosine receptor A1 (Mus musculus)	BDBM50517301 (CHEMBL1877326) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar	Purchase PC cid PC sid UniChem	Article PubMed	0.140	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Medical College of Wisconsin Curated by ChEMBL					Assay Description Displacement of [3H]N6-R-phenylisopropyladenosine from mouse A1A adenosine receptor expressed in CHO cell membranes after 60 mins by scintillation pr...				J Med Chem 62: 1502-1522 (2019) Article DOI: 10.1021/acs.jmedchem.8b01662
Medical College of Wisconsin Curated by ChEMBL					More data for this Ligand-Target Pair
Adenosine receptor A1 (Mus musculus)	BDBM50003019 (8-(Hexahydro-2,5-methano-pentalen-3a-yl)-1,3-dipro...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar	Purchase CHEMBL DrugBank PC cid PC sid UniChem Patents Similars	Article PubMed	0.145	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Bonn Curated by ChEMBL					Assay Description Binding affinity to mouse adenosine A1 receptor				Bioorg Med Chem 18: 2195-203 (2010) Article DOI: 10.1016/j.bmc.2010.01.072 BindingDB Entry DOI: 10.7270/Q2BZ670J
University of Bonn Curated by ChEMBL					More data for this Ligand-Target Pair
Adenosine receptor A1 (Homo sapiens (Human))	BDBM50382491 (CHEMBL2024114 \| US10988455, Example 1(xlii)) Show SMILES Nc1nnc(-c2ccc(O)c(Cl)c2)c(n1)-c1ccccc1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar	CHEMBL PC cid PC sid PDB UniChem Similars	US Patent	0.145	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Heptares Therapeutics Limited US Patent					Assay Description All test compounds were prepared as a stock solution of 10 mM in 100% DMSO.Inhibition binding assays were performed using 2.5 μg of membranes pr...				US Patent US10988455 (2021)
Heptares Therapeutics Limited US Patent					More data for this Ligand-Target Pair
Adenosine receptor A1 (BOVINE)	BDBM50090697 (7-Chloro-2-phenyl-[1,8]naphthyridin-4-ol \| 7-chlor...) Show SMILES Oc1cc(nc2nc(Cl)ccc12)-c1ccccc1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	0.150	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Pisa Curated by ChEMBL					Assay Description Ability to displace the specific binding of [3H]CHA to adenosine A1 receptor from bovine brain cortical membranes				J Med Chem 43: 2814-23 (2000) Article DOI: 10.1021/jm990321p BindingDB Entry DOI: 10.7270/Q21R6R6K
Universit£ di Pisa Curated by ChEMBL					More data for this Ligand-Target Pair
Adenosine receptor A1 (Homo sapiens (Human))	BDBM50055096 (CHEMBL3317576) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.150	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Firenze Curated by ChEMBL					Assay Description Displacement of [3H]-DPCPX from human adenosine A1 receptor expressed in CHO cells by scintillation counting analysis				Eur J Med Chem 84: 614-27 (2014) Article DOI: 10.1016/j.ejmech.2014.07.060 BindingDB Entry DOI: 10.7270/Q2BG2QNH
Universit£ di Firenze Curated by ChEMBL					More data for this Ligand-Target Pair
Adenosine receptor A1 (BOVINE)	BDBM50008415 (2-(2-Chloro-6-cyclopentylamino-purin-9-yl)-5-hydro...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar	PC cid PC sid UniChem Similars	Article PubMed	0.150	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universität Heidelberg Curated by PDSP K_i Database									Naunyn Schmiedebergs Arch Pharmacol 343: 196-201 (1991) Article DOI: 10.1007/bf00168610 BindingDB Entry DOI: 10.7270/Q22V2DMN
Universität Heidelberg Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Adenosine receptor A1 (BOVINE)	BDBM50090697 (7-Chloro-2-phenyl-[1,8]naphthyridin-4-ol \| 7-chlor...) Show SMILES Oc1cc(nc2nc(Cl)ccc12)-c1ccccc1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	0.150	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Università di Pisa Curated by ChEMBL					Assay Description Binding affinity against adenosine A1 receptor in bovine cortical membranes using [3H]-CHA as radioligand				J Med Chem 47: 3019-31 (2004) Article DOI: 10.1021/jm030977p BindingDB Entry DOI: 10.7270/Q2BC3Z07
Università di Pisa Curated by ChEMBL					More data for this Ligand-Target Pair
Adenosine receptor A1 (GUINEA PIG)	BDBM50008415 (2-(2-Chloro-6-cyclopentylamino-purin-9-yl)-5-hydro...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar	PC cid PC sid UniChem Similars	Article PubMed	0.150	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universität Heidelberg Curated by PDSP K_i Database									Naunyn Schmiedebergs Arch Pharmacol 343: 196-201 (1991) Article DOI: 10.1007/bf00168610 BindingDB Entry DOI: 10.7270/Q22V2DMN
Universität Heidelberg Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Adenosine receptor A1 (BOVINE)	BDBM21173 (1,3-dipropyl-8-cyclopentylxanthine \| 8-cyclopentyl...) Show SMILES CCCn1c2nc([nH]c2c(=O)n(CCC)c1=O)C1CCCC1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar	Purchase CHEBI CHEMBL KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	0.155	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Forschungszentrum Jülich GmbH Curated by ChEMBL					Assay Description Displacement of [3H]-CPX from Adenosine A1 receptor of bovine brain cerebral cortex membranes				J Med Chem 41: 555-63 (1998) Article DOI: 10.1021/jm9705465 BindingDB Entry DOI: 10.7270/Q2RX9B60
Forschungszentrum Jülich GmbH Curated by ChEMBL					More data for this Ligand-Target Pair
Adenosine receptor A1 (BOVINE)	BDBM21173 (1,3-dipropyl-8-cyclopentylxanthine \| 8-cyclopentyl...) Show SMILES CCCn1c2nc([nH]c2c(=O)n(CCC)c1=O)C1CCCC1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar	Purchase CHEBI CHEMBL KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	0.155	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Forschungszentrum Jülich GmbH Curated by ChEMBL					Assay Description Displacement of [3H]-CPX from Adenosine A1 receptor of bovine brain cerebral cortex membranes				J Med Chem 41: 555-63 (1998) Article DOI: 10.1021/jm9705465 BindingDB Entry DOI: 10.7270/Q2RX9B60
Forschungszentrum Jülich GmbH Curated by ChEMBL					More data for this Ligand-Target Pair
Adenosine receptor A1 (Homo sapiens (Human))	BDBM50382491 (CHEMBL2024114 \| US10988455, Example 1(xlii)) Show SMILES Nc1nnc(-c2ccc(O)c(Cl)c2)c(n1)-c1ccccc1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar	CHEMBL PC cid PC sid PDB UniChem Similars	Article PubMed	0.162	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Heptares Therapeutics Limited Curated by ChEMBL					Assay Description Displacement of [3H]DPCPX from human adenosine A1 receptor expressed in CHO cells after 1 hr by liquid scintillation counting				J Med Chem 55: 1898-903 (2012) Article DOI: 10.1021/jm201376w BindingDB Entry DOI: 10.7270/Q2S46SZG
Heptares Therapeutics Limited Curated by ChEMBL					More data for this Ligand-Target Pair
Adenosine receptor A1 (Rattus norvegicus (rat))	BDBM50140279 (CHEMBL3754252) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar	CHEMBL PC cid PC sid UniChem	Article PubMed	0.175	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
North-West University Curated by ChEMBL					Assay Description Displacement of [3H]DPCPX from adenosine A1 receptor in Sprague-Dawley rat whole brain after 1 hr by scintillation counting				Bioorg Med Chem Lett 26: 734-8 (2016) Article DOI: 10.1016/j.bmcl.2016.01.004 BindingDB Entry DOI: 10.7270/Q2SX6G21
North-West University Curated by ChEMBL					More data for this Ligand-Target Pair
Adenosine receptor A1 (BOVINE)	BDBM50062852 (8-Cyclopentyl-3-(3-fluoro-propyl)-1-propyl-3,7-dih...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	0.180	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Forschungszentrum Jülich GmbH Curated by ChEMBL					Assay Description In vitro binding affinity for Adenosine A1 receptor of bovine cortex				J Med Chem 45: 5150-6 (2002) Article DOI: 10.1021/jm020905i BindingDB Entry DOI: 10.7270/Q21J993X
Forschungszentrum Jülich GmbH Curated by ChEMBL					More data for this Ligand-Target Pair
Adenosine receptor A1 (Rattus norvegicus (rat))	BDBM21173 (1,3-dipropyl-8-cyclopentylxanthine \| 8-cyclopentyl...) Show SMILES CCCn1c2nc([nH]c2c(=O)n(CCC)c1=O)C1CCCC1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar	Purchase CHEBI CHEMBL KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	0.180	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universität Heidelberg Curated by PDSP K_i Database									Naunyn Schmiedebergs Arch Pharmacol 343: 196-201 (1991) Article DOI: 10.1007/bf00168610 BindingDB Entry DOI: 10.7270/Q22V2DMN
Universität Heidelberg Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Adenosine receptor A1 (BOVINE)	BDBM50062852 (8-Cyclopentyl-3-(3-fluoro-propyl)-1-propyl-3,7-dih...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	0.183	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Forschungszentrum Jülich GmbH Curated by ChEMBL					Assay Description Displacement of [3H]-CPX from Adenosine A1 receptor of bovine brain cerebral cortex membranes				J Med Chem 41: 555-63 (1998) Article DOI: 10.1021/jm9705465 BindingDB Entry DOI: 10.7270/Q2RX9B60
Forschungszentrum Jülich GmbH Curated by ChEMBL					More data for this Ligand-Target Pair
Adenosine receptor A1 (Rattus norvegicus (rat))	BDBM50003019 (8-(Hexahydro-2,5-methano-pentalen-3a-yl)-1,3-dipro...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar	Purchase CHEMBL DrugBank PC cid PC sid UniChem Patents Similars	PubMed	0.190	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Bonn Curated by ChEMBL					Assay Description Displacement of [3H]CCPA from adenosine receptor A1 in rat brain cortex membranes incubated for 90 mins by radioligand competition assay				Eur J Med Chem 186: (2020)
University of Bonn Curated by ChEMBL					More data for this Ligand-Target Pair
Adenosine receptor A1 (Rattus norvegicus (rat))	BDBM50044431 (8-(Hexahydro-2,5-methano-pentalen-3a-yl)-1,3-dipro...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	0.190	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Kyowa Hakko Kogyo Co., Ltd Curated by ChEMBL					Assay Description Tested for binding affinity against Adenosine A1 receptor from rat forebrain membranes, using N6-[3H]- cyclohexyladenosine as radioligand				J Med Chem 36: 2508-18 (1993) Article DOI: 10.1021/jm00069a009 BindingDB Entry DOI: 10.7270/Q2GX4C5K
Kyowa Hakko Kogyo Co., Ltd Curated by ChEMBL					More data for this Ligand-Target Pair
Adenosine receptor A1 (Rattus norvegicus (rat))	BDBM50003019 (8-(Hexahydro-2,5-methano-pentalen-3a-yl)-1,3-dipro...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar	Purchase CHEMBL DrugBank PC cid PC sid UniChem Patents Similars	Article PubMed	0.190	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Kyowa Hakko Kogyo Co., Ltd Curated by ChEMBL					Assay Description Binding affinity towards adenosine A1 receptor in rat forebrain membranes using N6-[3H]cyclohexyladenosine				J Med Chem 35: 3066-75 (1992) Article DOI: 10.1021/jm00094a022 BindingDB Entry DOI: 10.7270/Q2DN45PF
Kyowa Hakko Kogyo Co., Ltd Curated by ChEMBL					More data for this Ligand-Target Pair
Adenosine receptor A1 (Rattus norvegicus (rat))	BDBM50003019 (8-(Hexahydro-2,5-methano-pentalen-3a-yl)-1,3-dipro...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar	Purchase CHEMBL DrugBank PC cid PC sid UniChem Patents Similars	Article PubMed	0.190	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Bonn Curated by ChEMBL					Assay Description Displacement of [3H]DPCPX from adenosine A1 receptor in rat brain cortical membrane in presence of 100 uM GTP				Bioorg Med Chem 18: 2195-203 (2010) Article DOI: 10.1016/j.bmc.2010.01.072 BindingDB Entry DOI: 10.7270/Q2BZ670J
University of Bonn Curated by ChEMBL					More data for this Ligand-Target Pair
Adenosine receptor A1 (Homo sapiens (Human))	BDBM50315545 (8-(2-Thioxo-7(3-m-chlorophenyl)-2-(2-furyl)thiazol...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.190	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Delhi Curated by ChEMBL					Assay Description Displacement of [3H]DPCPX from human adenosine A1 receptor expressed in HEK293 cells after 60 mins by rapid filtration assay				Bioorg Med Chem 18: 2491-500 (2010) Article DOI: 10.1016/j.bmc.2010.02.048 BindingDB Entry DOI: 10.7270/Q27W6D57
University of Delhi Curated by ChEMBL					More data for this Ligand-Target Pair
Adenosine receptor A1 (BOVINE)	BDBM50003019 (8-(Hexahydro-2,5-methano-pentalen-3a-yl)-1,3-dipro...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar	Purchase CHEMBL DrugBank PC cid PC sid UniChem Patents Similars	Article PubMed	0.190	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Genova Curated by ChEMBL					Assay Description Binding affinity at bovine Adenosine A1 receptor.				J Med Chem 45: 4875-87 (2002) Article DOI: 10.1021/jm0209580 BindingDB Entry DOI: 10.7270/Q2N87BHS
Universit£ degli Studi di Genova Curated by ChEMBL					More data for this Ligand-Target Pair
Adenosine receptor A1 (Homo sapiens (Human))	BDBM50231595 (CHEMBL4092832) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.200	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Advinus Therapeutics Ltd Curated by ChEMBL					Assay Description Antagonist activity at human adenosine A1 receptor expressed in HEK293 cells assessed as reduction in CPA-mediated inhibition of forskolin-stimulated...				Bioorg Med Chem 25: 1963-1975 (2017) Article DOI: 10.1016/j.bmc.2017.02.029 BindingDB Entry DOI: 10.7270/Q2KH0QKC
Advinus Therapeutics Ltd Curated by ChEMBL					More data for this Ligand-Target Pair
Adenosine receptor A1 (Oryctolagus cuniculus (Rabbit))	BDBM50008415 (2-(2-Chloro-6-cyclopentylamino-purin-9-yl)-5-hydro...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar	PC cid PC sid UniChem Similars	Article PubMed	0.200	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universität Heidelberg Curated by PDSP K_i Database									Naunyn Schmiedebergs Arch Pharmacol 343: 196-201 (1991) Article DOI: 10.1007/bf00168610 BindingDB Entry DOI: 10.7270/Q22V2DMN
Universität Heidelberg Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Adenosine receptor A1 (BOVINE)	BDBM50207816 (CHEMBL273094 \| N-(2-Amino-ethyl)-2-[4-(2,6-dioxo-1...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar	Purchase CHEMBL MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	0.200	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universität Heidelberg Curated by PDSP K_i Database									Naunyn Schmiedebergs Arch Pharmacol 336: 204-10 (1987) Article DOI: 10.1007/bf00165806 BindingDB Entry DOI: 10.7270/Q26H4FXN
Universität Heidelberg Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Adenosine receptor A1 (Mus musculus)	BDBM50517302 (CHEMBL4562258) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar	Purchase PC cid PC sid UniChem	Article PubMed	0.200	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Medical College of Wisconsin Curated by ChEMBL					Assay Description Displacement of [3H]N6-R-phenylisopropyladenosine from mouse A1A adenosine receptor expressed in CHO cell membranes after 60 mins by scintillation pr...				J Med Chem 62: 1502-1522 (2019) Article DOI: 10.1021/acs.jmedchem.8b01662
Medical College of Wisconsin Curated by ChEMBL					More data for this Ligand-Target Pair
Adenosine receptor A1 (Mus musculus)	BDBM50085658 ((2R,3R,4S,5R)-2-(2-Chloro-6-cyclopentylamino-purin...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	0.210	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Medical College of Wisconsin Curated by ChEMBL					Assay Description Displacement of [3H]N6-R-phenylisopropyladenosine from mouse A1A adenosine receptor expressed in CHO cell membranes after 60 mins by scintillation pr...				J Med Chem 62: 1502-1522 (2019) Article DOI: 10.1021/acs.jmedchem.8b01662
Medical College of Wisconsin Curated by ChEMBL					More data for this Ligand-Target Pair
Adenosine receptor A1 (Oryctolagus cuniculus (Rabbit))	BDBM21173 (1,3-dipropyl-8-cyclopentylxanthine \| 8-cyclopentyl...) Show SMILES CCCn1c2nc([nH]c2c(=O)n(CCC)c1=O)C1CCCC1 Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar	Purchase CHEBI CHEMBL KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	0.210	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universität Heidelberg Curated by PDSP K_i Database									Naunyn Schmiedebergs Arch Pharmacol 343: 196-201 (1991) Article DOI: 10.1007/bf00168610 BindingDB Entry DOI: 10.7270/Q22V2DMN
Universität Heidelberg Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Adenosine receptor A1 (Rattus norvegicus (rat))	BDBM21173 (1,3-dipropyl-8-cyclopentylxanthine \| 8-cyclopentyl...) Show SMILES CCCn1c2nc([nH]c2c(=O)n(CCC)c1=O)C1CCCC1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar	Purchase CHEBI CHEMBL KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	0.211	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
North-West University Curated by ChEMBL					Assay Description Displacement of [3H]-DPCPX from Adenosine A1 receptor in Sprague-Dawley rat brain cortical membranes in presence of 0.1 mM GTP				Bioorg Med Chem 23: 6641-9 (2015) Article DOI: 10.1016/j.bmc.2015.09.012 BindingDB Entry DOI: 10.7270/Q2571DTP
North-West University Curated by ChEMBL					More data for this Ligand-Target Pair
Adenosine receptor A1 (BOVINE)	BDBM50062853 (8-Cyclopentyl-1-(3-fluoro-propyl)-3,7-dihydro-puri...) Show SMILES FCCCn1c(=O)[nH]c2nc([nH]c2c1=O)C1CCCC1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.216	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Forschungszentrum Jülich GmbH Curated by ChEMBL					Assay Description Displacement of [3H]-CPX from Adenosine A1 receptor of bovine brain cerebral cortex membranes				J Med Chem 41: 555-63 (1998) Article DOI: 10.1021/jm9705465 BindingDB Entry DOI: 10.7270/Q2RX9B60
Forschungszentrum Jülich GmbH Curated by ChEMBL					More data for this Ligand-Target Pair
Adenosine receptor A1 (Mus musculus)	BDBM25400 ((2R,3R,4S,5R)-2-[6-(cyclopentylamino)-9H-purin-9-y...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar	Purchase CHEMBL MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	0.220	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Medical College of Wisconsin Curated by ChEMBL					Assay Description Displacement of [3H]N6-R-phenylisopropyladenosine from mouse A1A adenosine receptor expressed in CHO cell membranes after 60 mins by scintillation pr...				J Med Chem 62: 1502-1522 (2019) Article DOI: 10.1021/acs.jmedchem.8b01662
Medical College of Wisconsin Curated by ChEMBL					More data for this Ligand-Target Pair
Adenosine receptor A1 (Homo sapiens (Human))	BDBM50055099 (CHEMBL3317579) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.220	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Firenze Curated by ChEMBL					Assay Description Displacement of [3H]-DPCPX from human adenosine A1 receptor expressed in CHO cells by scintillation counting analysis				Eur J Med Chem 84: 614-27 (2014) Article DOI: 10.1016/j.ejmech.2014.07.060 BindingDB Entry DOI: 10.7270/Q2BG2QNH
Universit£ di Firenze Curated by ChEMBL					More data for this Ligand-Target Pair
Adenosine receptor A1 (Rattus norvegicus (rat))	BDBM50368538 (CHEMBL610439) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.220	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
NIDDK Curated by ChEMBL					Assay Description Binding affinity for Adenosine A1 receptor using [3H]- CHA or [3H]- PIA				J Med Chem 35: 407-22 (1992) Article DOI: 10.1021/jm00081a001 BindingDB Entry DOI: 10.7270/Q2Z89D1W
NIDDK Curated by ChEMBL					More data for this Ligand-Target Pair

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