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Compile Data Set for Download or QSAR

Found 490 hits Enz. Inhib. hit(s) with Target = 'Ubiquitin carboxyl-terminal hydrolase 2'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Ubiquitin carboxyl-terminal hydrolase 28


(Homo sapiens)
BDBM482009
PNG
(US10913753, Compound I-76)
Show SMILES Cc1ccc2c(N)c(sc2n1)C(=O)NCCc1ccc(cc1Cl)N1CCNCC1
Show InChI InChI=1S/C21H24ClN5OS/c1-13-2-5-16-18(23)19(29-21(16)26-13)20(28)25-7-6-14-3-4-15(12-17(14)22)27-10-8-24-9-11-27/h2-5,12,24H,6-11,23H2,1H3,(H,25,28)
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n/an/a<200n/an/an/an/an/an/a



VALO EARLY DISCOVERY, INC.

US Patent


Assay Description
USP28: The assay was performed in a final volume of 20 uL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HCl, pH 8.0 solution; Corning 4...


US Patent US10913753 (2021)

More data for this
Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 28


(Homo sapiens)
BDBM482011
PNG
(US10913753, Compound I-78)
Show SMILES CCc1cc(CCNC(=O)c2sc3nc(C)ccc3c2N)ccc1N1CCNCC1
Show InChI InChI=1S/C23H29N5OS/c1-3-17-14-16(5-7-19(17)28-12-10-25-11-13-28)8-9-26-22(29)21-20(24)18-6-4-15(2)27-23(18)30-21/h4-7,14,25H,3,8-13,24H2,1-2H3,(H,26,29)
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n/an/a<200n/an/an/an/an/an/a



VALO EARLY DISCOVERY, INC.

US Patent


Assay Description
USP28: The assay was performed in a final volume of 20 uL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HCl, pH 8.0 solution; Corning 4...


US Patent US10913753 (2021)

More data for this
Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 28


(Homo sapiens)
BDBM482014
PNG
(US10913753, Compound I-81)
Show SMILES Cc1ccc2c(N)c(sc2n1)C(=O)NCCc1ccc(cc1C1CC1)N1CCNCC1
Show InChI InChI=1S/C24H29N5OS/c1-15-2-7-19-21(25)22(31-24(19)28-15)23(30)27-9-8-17-5-6-18(14-20(17)16-3-4-16)29-12-10-26-11-13-29/h2,5-7,14,16,26H,3-4,8-13,25H2,1H3,(H,27,30)
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n/an/a<200n/an/an/an/an/an/a



VALO EARLY DISCOVERY, INC.

US Patent


Assay Description
USP28: The assay was performed in a final volume of 20 uL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HCl, pH 8.0 solution; Corning 4...


US Patent US10913753 (2021)

More data for this
Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 25


(Homo sapiens)
BDBM482014
PNG
(US10913753, Compound I-81)
Show SMILES Cc1ccc2c(N)c(sc2n1)C(=O)NCCc1ccc(cc1C1CC1)N1CCNCC1
Show InChI InChI=1S/C24H29N5OS/c1-15-2-7-19-21(25)22(31-24(19)28-15)23(30)27-9-8-17-5-6-18(14-20(17)16-3-4-16)29-12-10-26-11-13-29/h2,5-7,14,16,26H,3-4,8-13,25H2,1H3,(H,27,30)
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n/an/a<200n/an/an/an/an/an/a



VALO EARLY DISCOVERY, INC.

US Patent


Assay Description
USP25: The assay was performed in a final volume of 9 uL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HC1, pH 8.0 solution; Corning 46...


US Patent US10913753 (2021)

More data for this
Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 28


(Homo sapiens)
BDBM482015
PNG
(US10913753, Compound I-82)
Show SMILES Cc1ccc2c(N)c(sc2n1)C(=O)NCCc1ccc(cc1-c1ccccc1)N1CCNCC1
Show InChI InChI=1S/C27H29N5OS/c1-18-7-10-22-24(28)25(34-27(22)31-18)26(33)30-12-11-20-8-9-21(32-15-13-29-14-16-32)17-23(20)19-5-3-2-4-6-19/h2-10,17,29H,11-16,28H2,1H3,(H,30,33)
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n/an/a<200n/an/an/an/an/an/a



VALO EARLY DISCOVERY, INC.

US Patent


Assay Description
USP28: The assay was performed in a final volume of 20 uL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HCl, pH 8.0 solution; Corning 4...


US Patent US10913753 (2021)

More data for this
Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 25


(Homo sapiens)
BDBM482015
PNG
(US10913753, Compound I-82)
Show SMILES Cc1ccc2c(N)c(sc2n1)C(=O)NCCc1ccc(cc1-c1ccccc1)N1CCNCC1
Show InChI InChI=1S/C27H29N5OS/c1-18-7-10-22-24(28)25(34-27(22)31-18)26(33)30-12-11-20-8-9-21(32-15-13-29-14-16-32)17-23(20)19-5-3-2-4-6-19/h2-10,17,29H,11-16,28H2,1H3,(H,30,33)
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n/an/a<200n/an/an/an/an/an/a



VALO EARLY DISCOVERY, INC.

US Patent


Assay Description
USP25: The assay was performed in a final volume of 9 uL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HC1, pH 8.0 solution; Corning 46...


US Patent US10913753 (2021)

More data for this
Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 28


(Homo sapiens)
BDBM482020
PNG
(US10913753, Compound I-87)
Show SMILES Cc1ccc2c(N)c(sc2n1)C(=O)NCCc1ccc(cc1)N1CCN[C@@H](CO)C1
Show InChI InChI=1S/C22H27N5O2S/c1-14-2-7-18-19(23)20(30-22(18)26-14)21(29)25-9-8-15-3-5-17(6-4-15)27-11-10-24-16(12-27)13-28/h2-7,16,24,28H,8-13,23H2,1H3,(H,25,29)/t16-/m1/s1
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n/an/a<200n/an/an/an/an/an/a



VALO EARLY DISCOVERY, INC.

US Patent


Assay Description
USP28: The assay was performed in a final volume of 20 uL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HCl, pH 8.0 solution; Corning 4...


US Patent US10913753 (2021)

More data for this
Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 28


(Homo sapiens)
BDBM482021
PNG
(US10913753, Compound I-88)
Show SMILES Cc1ccc2c(N)c(sc2n1)C(=O)NCCc1ccc(N2CC3CCC(C2)N3)c(F)c1
Show InChI InChI=1S/C23H26FN5OS/c1-13-2-6-17-20(25)21(31-23(17)27-13)22(30)26-9-8-14-3-7-19(18(24)10-14)29-11-15-4-5-16(12-29)28-15/h2-3,6-7,10,15-16,28H,4-5,8-9,11-12,25H2,1H3,(H,26,30)
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n/an/a<200n/an/an/an/an/an/a



VALO EARLY DISCOVERY, INC.

US Patent


Assay Description
USP28: The assay was performed in a final volume of 20 uL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HCl, pH 8.0 solution; Corning 4...


US Patent US10913753 (2021)

More data for this
Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 28


(Homo sapiens)
BDBM482022
PNG
(US10913753, Compound I-89)
Show SMILES Cc1ccc2c(N)c(sc2n1)C(=O)NCCc1ccc(cc1C)N1CCNCC1
Show InChI InChI=1S/C22H27N5OS/c1-14-13-17(27-11-9-24-10-12-27)5-4-16(14)7-8-25-21(28)20-19(23)18-6-3-15(2)26-22(18)29-20/h3-6,13,24H,7-12,23H2,1-2H3,(H,25,28)
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n/an/a<200n/an/an/an/an/an/a



VALO EARLY DISCOVERY, INC.

US Patent


Assay Description
USP28: The assay was performed in a final volume of 20 uL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HCl, pH 8.0 solution; Corning 4...


US Patent US10913753 (2021)

More data for this
Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 28


(Homo sapiens)
BDBM482026
PNG
(US10913753, Compound I-93 | US10913753, Compound I...)
Show SMILES Cc1ccc2c(N)c(sc2n1)C(=O)NCCc1ccc(cc1)N1CC[C@H]2NCC[C@@H]12
Show InChI InChI=1S/C23H27N5OS/c1-14-2-7-17-20(24)21(30-23(17)27-14)22(29)26-11-8-15-3-5-16(6-4-15)28-13-10-18-19(28)9-12-25-18/h2-7,18-19,25H,8-13,24H2,1H3,(H,26,29)/t18-,19-/m1/s1
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n/an/a<200n/an/an/an/an/an/a



VALO EARLY DISCOVERY, INC.

US Patent


Assay Description
USP28: The assay was performed in a final volume of 20 uL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HCl, pH 8.0 solution; Corning 4...


US Patent US10913753 (2021)

More data for this
Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 25


(Homo sapiens)
BDBM482026
PNG
(US10913753, Compound I-93 | US10913753, Compound I...)
Show SMILES Cc1ccc2c(N)c(sc2n1)C(=O)NCCc1ccc(cc1)N1CC[C@H]2NCC[C@@H]12
Show InChI InChI=1S/C23H27N5OS/c1-14-2-7-17-20(24)21(30-23(17)27-14)22(29)26-11-8-15-3-5-16(6-4-15)28-13-10-18-19(28)9-12-25-18/h2-7,18-19,25H,8-13,24H2,1H3,(H,26,29)/t18-,19-/m1/s1
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n/an/a<200n/an/an/an/an/an/a



VALO EARLY DISCOVERY, INC.

US Patent


Assay Description
USP25: The assay was performed in a final volume of 9 uL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HC1, pH 8.0 solution; Corning 46...


US Patent US10913753 (2021)

More data for this
Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 28


(Homo sapiens)
BDBM482028
PNG
(US10913753, Compound I-95)
Show SMILES Cc1ccc2c(N)c(sc2n1)C(=O)NCCc1cc(F)c(cc1F)N1C[C@@H]2CCN[C@@H]2C1
Show InChI InChI=1S/C23H25F2N5OS/c1-12-2-3-15-20(26)21(32-23(15)29-12)22(31)28-7-4-13-8-17(25)19(9-16(13)24)30-10-14-5-6-27-18(14)11-30/h2-3,8-9,14,18,27H,4-7,10-11,26H2,1H3,(H,28,31)/t14-,18+/m0/s1
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n/an/a<200n/an/an/an/an/an/a



VALO EARLY DISCOVERY, INC.

US Patent


Assay Description
USP28: The assay was performed in a final volume of 20 uL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HCl, pH 8.0 solution; Corning 4...


US Patent US10913753 (2021)

More data for this
Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 28


(Homo sapiens)
BDBM482029
PNG
(US10913753, Compound I-96)
Show SMILES Cc1ccc2c(N)c(sc2n1)C(=O)NCCc1cc(F)c(cc1F)N1C[C@H]2CCN[C@H]2C1
Show InChI InChI=1S/C23H25F2N5OS/c1-12-2-3-15-20(26)21(32-23(15)29-12)22(31)28-7-4-13-8-17(25)19(9-16(13)24)30-10-14-5-6-27-18(14)11-30/h2-3,8-9,14,18,27H,4-7,10-11,26H2,1H3,(H,28,31)/t14-,18+/m1/s1
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n/an/a<200n/an/an/an/an/an/a



VALO EARLY DISCOVERY, INC.

US Patent


Assay Description
USP28: The assay was performed in a final volume of 20 uL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HCl, pH 8.0 solution; Corning 4...


US Patent US10913753 (2021)

More data for this
Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 28


(Homo sapiens)
BDBM482031
PNG
(US10913753, Compound I-98)
Show SMILES C[C@@H](CNC(=O)c1sc2nc(C)ccc2c1N)c1cc(F)c(cc1F)N1CC2CCC(C1)N2
Show InChI InChI=1S/C24H27F2N5OS/c1-12(9-28-23(32)22-21(27)16-6-3-13(2)29-24(16)33-22)17-7-19(26)20(8-18(17)25)31-10-14-4-5-15(11-31)30-14/h3,6-8,12,14-15,30H,4-5,9-11,27H2,1-2H3,(H,28,32)/t12-,14?,15?/m0/s1
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n/an/a<200n/an/an/an/an/an/a



VALO EARLY DISCOVERY, INC.

US Patent


Assay Description
USP28: The assay was performed in a final volume of 20 uL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HCl, pH 8.0 solution; Corning 4...


US Patent US10913753 (2021)

More data for this
Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 28


(Homo sapiens)
BDBM482044
PNG
(US10913753, Compound I-111)
Show SMILES C[C@H](CNC(=O)c1sc2nc(C)c(F)cc2c1N)c1cc(F)c(cc1F)N1CC2CCC(C1)N2
Show InChI InChI=1S/C24H26F3N5OS/c1-11(8-29-23(33)22-21(28)16-6-17(25)12(2)30-24(16)34-22)15-5-19(27)20(7-18(15)26)32-9-13-3-4-14(10-32)31-13/h5-7,11,13-14,31H,3-4,8-10,28H2,1-2H3,(H,29,33)/t11-,13?,14?/m1/s1
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n/an/a<200n/an/an/an/an/an/a



VALO EARLY DISCOVERY, INC.

US Patent


Assay Description
USP28: The assay was performed in a final volume of 20 uL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HCl, pH 8.0 solution; Corning 4...


US Patent US10913753 (2021)

More data for this
Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 28


(Homo sapiens)
BDBM482046
PNG
(US10913753, Compound I-113)
Show SMILES Cc1ccc2c(N)c(sc2n1)C(=O)NCCc1cc(F)c(cc1F)C1CCNCC1
Show InChI InChI=1S/C22H24F2N4OS/c1-12-2-3-15-19(25)20(30-22(15)28-12)21(29)27-9-6-14-10-18(24)16(11-17(14)23)13-4-7-26-8-5-13/h2-3,10-11,13,26H,4-9,25H2,1H3,(H,27,29)
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n/an/a<200n/an/an/an/an/an/a



VALO EARLY DISCOVERY, INC.

US Patent


Assay Description
USP28: The assay was performed in a final volume of 20 uL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HCl, pH 8.0 solution; Corning 4...


US Patent US10913753 (2021)

More data for this
Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 28


(Homo sapiens)
BDBM482047
PNG
(US10913753, Compound I-114)
Show SMILES Nc1c(sc2nc(ccc12)C1CC1)C(=O)NCCc1ccc(cc1)N1CCNCC1
Show InChI InChI=1S/C23H27N5OS/c24-20-18-7-8-19(16-3-4-16)27-23(18)30-21(20)22(29)26-10-9-15-1-5-17(6-2-15)28-13-11-25-12-14-28/h1-2,5-8,16,25H,3-4,9-14,24H2,(H,26,29)
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n/an/a<200n/an/an/an/an/an/a



VALO EARLY DISCOVERY, INC.

US Patent


Assay Description
USP28: The assay was performed in a final volume of 20 uL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HCl, pH 8.0 solution; Corning 4...


US Patent US10913753 (2021)

More data for this
Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 28


(Homo sapiens)
BDBM482048
PNG
(US10913753, Compound I-115)
Show SMILES Nc1c(sc2nc(N)c(F)cc12)C(=O)NCCc1ccc(cc1)N1CCNCC1
Show InChI InChI=1S/C20H23FN6OS/c21-15-11-14-16(22)17(29-20(14)26-18(15)23)19(28)25-6-5-12-1-3-13(4-2-12)27-9-7-24-8-10-27/h1-4,11,24H,5-10,22H2,(H2,23,26)(H,25,28)
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n/an/a<200n/an/an/an/an/an/a



VALO EARLY DISCOVERY, INC.

US Patent


Assay Description
USP28: The assay was performed in a final volume of 20 uL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HCl, pH 8.0 solution; Corning 4...


US Patent US10913753 (2021)

More data for this
Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 28


(Homo sapiens)
BDBM482053
PNG
(US10913753, Compound I-120)
Show SMILES Cc1ccc2c(N)c(sc2n1)C(=O)NCCc1ccc(cc1)N1CCn2cncc2C1
Show InChI InChI=1S/C23H24N6OS/c1-15-2-7-19-20(24)21(31-23(19)27-15)22(30)26-9-8-16-3-5-17(6-4-16)28-10-11-29-14-25-12-18(29)13-28/h2-7,12,14H,8-11,13,24H2,1H3,(H,26,30)
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n/an/a<200n/an/an/an/an/an/a



VALO EARLY DISCOVERY, INC.

US Patent


Assay Description
USP28: The assay was performed in a final volume of 20 uL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HCl, pH 8.0 solution; Corning 4...


US Patent US10913753 (2021)

More data for this
Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 28


(Homo sapiens)
BDBM482056
PNG
(US10913753, Compound I-123 | US10913753, Compound ...)
Show SMILES Cc1ccc2c(N)c(sc2n1)C(=O)NCCc1ccc(cc1)N1CCC2(C1)CCCNC2
Show InChI InChI=1S/C25H31N5OS/c1-17-3-8-20-21(26)22(32-24(20)29-17)23(31)28-13-9-18-4-6-19(7-5-18)30-14-11-25(16-30)10-2-12-27-15-25/h3-8,27H,2,9-16,26H2,1H3,(H,28,31)
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n/an/a<200n/an/an/an/an/an/a



VALO EARLY DISCOVERY, INC.

US Patent


Assay Description
USP28: The assay was performed in a final volume of 20 uL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HCl, pH 8.0 solution; Corning 4...


US Patent US10913753 (2021)

More data for this
Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 28


(Homo sapiens)
BDBM482063
PNG
(US10913753, Compound I-130)
Show SMILES Cc1ccc2c(N)c(sc2n1)C(=O)NCCc1ccc(cc1)N1C[C@H]2C[C@@H]1CN2
Show InChI InChI=1S/C22H25N5OS/c1-13-2-7-18-19(23)20(29-22(18)26-13)21(28)24-9-8-14-3-5-16(6-4-14)27-12-15-10-17(27)11-25-15/h2-7,15,17,25H,8-12,23H2,1H3,(H,24,28)/t15-,17-/m1/s1
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n/an/a<200n/an/an/an/an/an/a



VALO EARLY DISCOVERY, INC.

US Patent


Assay Description
USP28: The assay was performed in a final volume of 20 uL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HCl, pH 8.0 solution; Corning 4...


US Patent US10913753 (2021)

More data for this
Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 25


(Homo sapiens)
BDBM482063
PNG
(US10913753, Compound I-130)
Show SMILES Cc1ccc2c(N)c(sc2n1)C(=O)NCCc1ccc(cc1)N1C[C@H]2C[C@@H]1CN2
Show InChI InChI=1S/C22H25N5OS/c1-13-2-7-18-19(23)20(29-22(18)26-13)21(28)24-9-8-14-3-5-16(6-4-14)27-12-15-10-17(27)11-25-15/h2-7,15,17,25H,8-12,23H2,1H3,(H,24,28)/t15-,17-/m1/s1
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n/an/a<200n/an/an/an/an/an/a



VALO EARLY DISCOVERY, INC.

US Patent


Assay Description
USP25: The assay was performed in a final volume of 9 uL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HC1, pH 8.0 solution; Corning 46...


US Patent US10913753 (2021)

More data for this
Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 28


(Homo sapiens)
BDBM482064
PNG
(US10913753, Compound I-131)
Show SMILES Cc1ccc2c(N)c(sc2n1)C(=O)NCCc1ccc(cc1)N1C[C@@H]2C[C@H]1CN2
Show InChI InChI=1S/C22H25N5OS/c1-13-2-7-18-19(23)20(29-22(18)26-13)21(28)24-9-8-14-3-5-16(6-4-14)27-12-15-10-17(27)11-25-15/h2-7,15,17,25H,8-12,23H2,1H3,(H,24,28)/t15-,17-/m0/s1
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n/an/a<200n/an/an/an/an/an/a



VALO EARLY DISCOVERY, INC.

US Patent


Assay Description
USP28: The assay was performed in a final volume of 20 uL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HCl, pH 8.0 solution; Corning 4...


US Patent US10913753 (2021)

More data for this
Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 28


(Homo sapiens)
BDBM482065
PNG
(US10913753, Compound I-132)
Show SMILES C[C@@H]1CNCCN1c1ccc(CCNC(=O)c2sc3nc(C)ccc3c2N)cc1
Show InChI InChI=1S/C22H27N5OS/c1-14-3-8-18-19(23)20(29-22(18)26-14)21(28)25-10-9-16-4-6-17(7-5-16)27-12-11-24-13-15(27)2/h3-8,15,24H,9-13,23H2,1-2H3,(H,25,28)/t15-/m1/s1
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n/an/a<200n/an/an/an/an/an/a



VALO EARLY DISCOVERY, INC.

US Patent


Assay Description
USP28: The assay was performed in a final volume of 20 uL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HCl, pH 8.0 solution; Corning 4...


US Patent US10913753 (2021)

More data for this
Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 25


(Homo sapiens)
BDBM482065
PNG
(US10913753, Compound I-132)
Show SMILES C[C@@H]1CNCCN1c1ccc(CCNC(=O)c2sc3nc(C)ccc3c2N)cc1
Show InChI InChI=1S/C22H27N5OS/c1-14-3-8-18-19(23)20(29-22(18)26-14)21(28)25-10-9-16-4-6-17(7-5-16)27-12-11-24-13-15(27)2/h3-8,15,24H,9-13,23H2,1-2H3,(H,25,28)/t15-/m1/s1
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n/an/a<200n/an/an/an/an/an/a



VALO EARLY DISCOVERY, INC.

US Patent


Assay Description
USP25: The assay was performed in a final volume of 9 uL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HC1, pH 8.0 solution; Corning 46...


US Patent US10913753 (2021)

More data for this
Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 28


(Homo sapiens)
BDBM482066
PNG
(US10913753, Compound I-133)
Show SMILES C[C@H]1CNCCN1c1ccc(CCNC(=O)c2sc3nc(C)ccc3c2N)cc1
Show InChI InChI=1S/C22H27N5OS/c1-14-3-8-18-19(23)20(29-22(18)26-14)21(28)25-10-9-16-4-6-17(7-5-16)27-12-11-24-13-15(27)2/h3-8,15,24H,9-13,23H2,1-2H3,(H,25,28)/t15-/m0/s1
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n/an/a<200n/an/an/an/an/an/a



VALO EARLY DISCOVERY, INC.

US Patent


Assay Description
USP28: The assay was performed in a final volume of 20 uL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HCl, pH 8.0 solution; Corning 4...


US Patent US10913753 (2021)

More data for this
Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 28


(Homo sapiens)
BDBM482067
PNG
(US10913753, Compound I-134)
Show SMILES C[C@@H]1CN(CCN1)c1ccc(CCNC(=O)c2sc3nc(C)ccc3c2N)cc1
Show InChI InChI=1S/C22H27N5OS/c1-14-3-8-18-19(23)20(29-22(18)26-14)21(28)25-10-9-16-4-6-17(7-5-16)27-12-11-24-15(2)13-27/h3-8,15,24H,9-13,23H2,1-2H3,(H,25,28)/t15-/m1/s1
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n/an/a<200n/an/an/an/an/an/a



VALO EARLY DISCOVERY, INC.

US Patent


Assay Description
USP28: The assay was performed in a final volume of 20 uL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HCl, pH 8.0 solution; Corning 4...


US Patent US10913753 (2021)

More data for this
Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 28


(Homo sapiens)
BDBM482068
PNG
(US10913753, Compound I-135)
Show SMILES CC(C)[C@@H]1CN(CCN1)c1ccc(CCNC(=O)c2sc3nc(C)ccc3c2N)cc1
Show InChI InChI=1S/C24H31N5OS/c1-15(2)20-14-29(13-12-26-20)18-7-5-17(6-8-18)10-11-27-23(30)22-21(25)19-9-4-16(3)28-24(19)31-22/h4-9,15,20,26H,10-14,25H2,1-3H3,(H,27,30)/t20-/m0/s1
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n/an/a<200n/an/an/an/an/an/a



VALO EARLY DISCOVERY, INC.

US Patent


Assay Description
USP28: The assay was performed in a final volume of 20 uL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HCl, pH 8.0 solution; Corning 4...


US Patent US10913753 (2021)

More data for this
Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 28


(Homo sapiens)
BDBM482071
PNG
(US10913753, Compound I-138)
Show SMILES Cc1ccc2c(N)c(sc2n1)C(=O)NCCc1ccc(cc1)N1CC2(C1)CCCN2
Show InChI InChI=1S/C23H27N5OS/c1-15-3-8-18-19(24)20(30-22(18)27-15)21(29)25-12-9-16-4-6-17(7-5-16)28-13-23(14-28)10-2-11-26-23/h3-8,26H,2,9-14,24H2,1H3,(H,25,29)
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n/an/a<200n/an/an/an/an/an/a



VALO EARLY DISCOVERY, INC.

US Patent


Assay Description
USP28: The assay was performed in a final volume of 20 uL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HCl, pH 8.0 solution; Corning 4...


US Patent US10913753 (2021)

More data for this
Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 28


(Homo sapiens)
BDBM482073
PNG
(US10913753, Compound I-140)
Show SMILES Cc1ccc2c(N)c(sc2n1)C(=O)NCCc1ccc(cc1)N1CCC2(CNC2)CC1
Show InChI InChI=1S/C24H29N5OS/c1-16-2-7-19-20(25)21(31-23(19)28-16)22(30)27-11-8-17-3-5-18(6-4-17)29-12-9-24(10-13-29)14-26-15-24/h2-7,26H,8-15,25H2,1H3,(H,27,30)
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n/an/a<200n/an/an/an/an/an/a



VALO EARLY DISCOVERY, INC.

US Patent


Assay Description
USP28: The assay was performed in a final volume of 20 uL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HCl, pH 8.0 solution; Corning 4...


US Patent US10913753 (2021)

More data for this
Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 28


(Homo sapiens)
BDBM482077
PNG
(US10913753, Compound I-144)
Show SMILES Cc1ccc2c(N)c(sc2n1)C(=O)NCCc1ccc(cc1)N1CCCC2(CCNCC2)C1
Show InChI InChI=1S/C26H33N5OS/c1-18-3-8-21-22(27)23(33-25(21)30-18)24(32)29-13-9-19-4-6-20(7-5-19)31-16-2-10-26(17-31)11-14-28-15-12-26/h3-8,28H,2,9-17,27H2,1H3,(H,29,32)
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n/an/a<200n/an/an/an/an/an/a



VALO EARLY DISCOVERY, INC.

US Patent


Assay Description
USP28: The assay was performed in a final volume of 20 uL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HCl, pH 8.0 solution; Corning 4...


US Patent US10913753 (2021)

More data for this
Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 28


(Homo sapiens)
BDBM482079
PNG
(US10913753, Compound I-146)
Show SMILES Cc1ccc2c(N)c(sc2n1)C(=O)NCCc1ccc(cc1)N1CCCC11CCCNC1
Show InChI InChI=1S/C25H31N5OS/c1-17-4-9-20-21(26)22(32-24(20)29-17)23(31)28-14-10-18-5-7-19(8-6-18)30-15-3-12-25(30)11-2-13-27-16-25/h4-9,27H,2-3,10-16,26H2,1H3,(H,28,31)
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n/an/a<200n/an/an/an/an/an/a



VALO EARLY DISCOVERY, INC.

US Patent


Assay Description
USP28: The assay was performed in a final volume of 20 uL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HCl, pH 8.0 solution; Corning 4...


US Patent US10913753 (2021)

More data for this
Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 28


(Homo sapiens)
BDBM482080
PNG
(US10913753, Compound I-147)
Show SMILES Cc1ccc2c(N)c(sc2n1)C(=O)NCCc1ccc(NC2CCNC2)cc1
Show InChI InChI=1S/C21H25N5OS/c1-13-2-7-17-18(22)19(28-21(17)25-13)20(27)24-11-8-14-3-5-15(6-4-14)26-16-9-10-23-12-16/h2-7,16,23,26H,8-12,22H2,1H3,(H,24,27)
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n/an/a<200n/an/an/an/an/an/a



VALO EARLY DISCOVERY, INC.

US Patent


Assay Description
USP28: The assay was performed in a final volume of 20 uL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HCl, pH 8.0 solution; Corning 4...


US Patent US10913753 (2021)

More data for this
Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 28


(Homo sapiens)
BDBM482102
PNG
(US10913753, Compound I-169)
Show SMILES Cc1ccc2c(N)c(sc2n1)C(=O)NCCc1ccc(C2CCNCC2)c(F)c1
Show InChI InChI=1S/C22H25FN4OS/c1-13-2-4-17-19(24)20(29-22(17)27-13)21(28)26-11-6-14-3-5-16(18(23)12-14)15-7-9-25-10-8-15/h2-5,12,15,25H,6-11,24H2,1H3,(H,26,28)
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n/an/a<200n/an/an/an/an/an/a



VALO EARLY DISCOVERY, INC.

US Patent


Assay Description
USP28: The assay was performed in a final volume of 20 uL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HCl, pH 8.0 solution; Corning 4...


US Patent US10913753 (2021)

More data for this
Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 28


(Homo sapiens)
BDBM482103
PNG
(US10913753, Compound I-170)
Show SMILES Cc1ccc2c(N)c(sc2n1)C(=O)NCCc1ccc(cc1F)C1CCNCC1
Show InChI InChI=1S/C22H25FN4OS/c1-13-2-5-17-19(24)20(29-22(17)27-13)21(28)26-11-8-15-3-4-16(12-18(15)23)14-6-9-25-10-7-14/h2-5,12,14,25H,6-11,24H2,1H3,(H,26,28)
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n/an/a<200n/an/an/an/an/an/a



VALO EARLY DISCOVERY, INC.

US Patent


Assay Description
USP28: The assay was performed in a final volume of 20 uL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HCl, pH 8.0 solution; Corning 4...


US Patent US10913753 (2021)

More data for this
Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 28


(Homo sapiens)
BDBM482105
PNG
(US10913753, Compound I-172)
Show SMILES Cc1ccc2c(N)c(sc2n1)C(=O)NCCc1ccc(cc1)C1CC2CCC(C1)N2
Show InChI InChI=1S/C24H28N4OS/c1-14-2-9-20-21(25)22(30-24(20)27-14)23(29)26-11-10-15-3-5-16(6-4-15)17-12-18-7-8-19(13-17)28-18/h2-6,9,17-19,28H,7-8,10-13,25H2,1H3,(H,26,29)
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n/an/a<200n/an/an/an/an/an/a



VALO EARLY DISCOVERY, INC.

US Patent


Assay Description
USP28: The assay was performed in a final volume of 20 uL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HCl, pH 8.0 solution; Corning 4...


US Patent US10913753 (2021)

More data for this
Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 25


(Homo sapiens)
BDBM482105
PNG
(US10913753, Compound I-172)
Show SMILES Cc1ccc2c(N)c(sc2n1)C(=O)NCCc1ccc(cc1)C1CC2CCC(C1)N2
Show InChI InChI=1S/C24H28N4OS/c1-14-2-9-20-21(25)22(30-24(20)27-14)23(29)26-11-10-15-3-5-16(6-4-15)17-12-18-7-8-19(13-17)28-18/h2-6,9,17-19,28H,7-8,10-13,25H2,1H3,(H,26,29)
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n/an/a<200n/an/an/an/an/an/a



VALO EARLY DISCOVERY, INC.

US Patent


Assay Description
USP25: The assay was performed in a final volume of 9 uL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HC1, pH 8.0 solution; Corning 46...


US Patent US10913753 (2021)

More data for this
Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 28


(Homo sapiens)
BDBM482113
PNG
(US10913753, Compound I-180)
Show SMILES Nc1c(sc2ncccc12)C(=O)NCCc1ccc(cc1)[C@H]1CCNC1
Show InChI InChI=1S/C20H22N4OS/c21-17-16-2-1-9-24-20(16)26-18(17)19(25)23-11-7-13-3-5-14(6-4-13)15-8-10-22-12-15/h1-6,9,15,22H,7-8,10-12,21H2,(H,23,25)/t15-/m0/s1
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n/an/a<200n/an/an/an/an/an/a



VALO EARLY DISCOVERY, INC.

US Patent


Assay Description
USP28: The assay was performed in a final volume of 20 uL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HCl, pH 8.0 solution; Corning 4...


US Patent US10913753 (2021)

More data for this
Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 28


(Homo sapiens)
BDBM482114
PNG
(US10913753, Compound I-181)
Show SMILES Nc1c(sc2ncccc12)C(=O)NCCc1ccc(cc1)C1CCNC1
Show InChI InChI=1S/C20H22N4OS/c21-17-16-2-1-9-24-20(16)26-18(17)19(25)23-11-7-13-3-5-14(6-4-13)15-8-10-22-12-15/h1-6,9,15,22H,7-8,10-12,21H2,(H,23,25)
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n/an/a<200n/an/an/an/an/an/a



VALO EARLY DISCOVERY, INC.

US Patent


Assay Description
USP28: The assay was performed in a final volume of 20 uL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HCl, pH 8.0 solution; Corning 4...


US Patent US10913753 (2021)

More data for this
Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 28


(Homo sapiens)
BDBM482121
PNG
(US10913753, Compound I-188)
Show SMILES CCNc1ccc2c(N)c(sc2n1)C(=O)NCCc1ccc(cc1)N1CCNCC1
Show InChI InChI=1S/C22H28N6OS/c1-2-25-18-8-7-17-19(23)20(30-22(17)27-18)21(29)26-10-9-15-3-5-16(6-4-15)28-13-11-24-12-14-28/h3-8,24H,2,9-14,23H2,1H3,(H,25,27)(H,26,29)
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n/an/a<200n/an/an/an/an/an/a



VALO EARLY DISCOVERY, INC.

US Patent


Assay Description
USP28: The assay was performed in a final volume of 20 uL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HCl, pH 8.0 solution; Corning 4...


US Patent US10913753 (2021)

More data for this
Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 28


(Homo sapiens)
BDBM482126
PNG
(US10913753, Compound I-193)
Show SMILES Nc1c(sc2nc(OC(F)F)ccc12)C(=O)NCCc1ccc(cc1)N1CCNCC1
Show InChI InChI=1S/C21H23F2N5O2S/c22-21(23)30-16-6-5-15-17(24)18(31-20(15)27-16)19(29)26-8-7-13-1-3-14(4-2-13)28-11-9-25-10-12-28/h1-6,21,25H,7-12,24H2,(H,26,29)
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n/an/a<200n/an/an/an/an/an/a



VALO EARLY DISCOVERY, INC.

US Patent


Assay Description
USP28: The assay was performed in a final volume of 20 uL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HCl, pH 8.0 solution; Corning 4...


US Patent US10913753 (2021)

More data for this
Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 28


(Homo sapiens)
BDBM482127
PNG
(US10913753, Compound I-194)
Show SMILES CNc1ccc2c(N)c(sc2n1)C(=O)NCCc1ccc(cc1)C1CCN(C)CC1
Show InChI InChI=1S/C23H29N5OS/c1-25-19-8-7-18-20(24)21(30-23(18)27-19)22(29)26-12-9-15-3-5-16(6-4-15)17-10-13-28(2)14-11-17/h3-8,17H,9-14,24H2,1-2H3,(H,25,27)(H,26,29)
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n/an/a<200n/an/an/an/an/an/a



VALO EARLY DISCOVERY, INC.

US Patent


Assay Description
USP28: The assay was performed in a final volume of 20 uL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HCl, pH 8.0 solution; Corning 4...


US Patent US10913753 (2021)

More data for this
Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 28


(Homo sapiens)
BDBM482128
PNG
(US10913753, Compound I-195)
Show SMILES CNc1ccc2c(N)c(sc2n1)C(=O)NCCc1ccc(cc1)N1CCN(C)CC1
Show InChI InChI=1S/C22H28N6OS/c1-24-18-8-7-17-19(23)20(30-22(17)26-18)21(29)25-10-9-15-3-5-16(6-4-15)28-13-11-27(2)12-14-28/h3-8H,9-14,23H2,1-2H3,(H,24,26)(H,25,29)
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n/an/a<200n/an/an/an/an/an/a



VALO EARLY DISCOVERY, INC.

US Patent


Assay Description
USP28: The assay was performed in a final volume of 20 uL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HCl, pH 8.0 solution; Corning 4...


US Patent US10913753 (2021)

More data for this
Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 25


(Homo sapiens)
BDBM482137
PNG
(US10913753, Compound I-204)
Show SMILES Cc1cc(c2c(N)c(sc2n1)C(=O)NCCc1ccc(cc1)N1CCNCC1)C(F)(F)F
Show InChI InChI=1S/C22H24F3N5OS/c1-13-12-16(22(23,24)25)17-18(26)19(32-21(17)29-13)20(31)28-7-6-14-2-4-15(5-3-14)30-10-8-27-9-11-30/h2-5,12,27H,6-11,26H2,1H3,(H,28,31)
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n/an/a<200n/an/an/an/an/an/a



VALO EARLY DISCOVERY, INC.

US Patent


Assay Description
USP25: The assay was performed in a final volume of 9 uL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HC1, pH 8.0 solution; Corning 46...


US Patent US10913753 (2021)

More data for this
Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 28


(Homo sapiens)
BDBM482138
PNG
(US10913753, Compound I-205)
Show SMILES Cc1ccc2c(N)c(sc2n1)C(=O)NCCc1ccc(C2CCNCC2)c(Cl)c1
Show InChI InChI=1S/C22H25ClN4OS/c1-13-2-4-17-19(24)20(29-22(17)27-13)21(28)26-11-6-14-3-5-16(18(23)12-14)15-7-9-25-10-8-15/h2-5,12,15,25H,6-11,24H2,1H3,(H,26,28)
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n/an/a<200n/an/an/an/an/an/a



VALO EARLY DISCOVERY, INC.

US Patent


Assay Description
USP28: The assay was performed in a final volume of 20 uL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HCl, pH 8.0 solution; Corning 4...


US Patent US10913753 (2021)

More data for this
Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 28


(Homo sapiens)
BDBM482139
PNG
(US10913753, Compound I-206)
Show SMILES CCc1nc2sc(C(=O)NCCc3ccc(cc3)N3CCNCC3)c(N)c2cc1F
Show InChI InChI=1S/C22H26FN5OS/c1-2-18-17(23)13-16-19(24)20(30-22(16)27-18)21(29)26-8-7-14-3-5-15(6-4-14)28-11-9-25-10-12-28/h3-6,13,25H,2,7-12,24H2,1H3,(H,26,29)
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n/an/a<200n/an/an/an/an/an/a



VALO EARLY DISCOVERY, INC.

US Patent


Assay Description
USP28: The assay was performed in a final volume of 20 uL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HCl, pH 8.0 solution; Corning 4...


US Patent US10913753 (2021)

More data for this
Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 25


(Homo sapiens)
BDBM482139
PNG
(US10913753, Compound I-206)
Show SMILES CCc1nc2sc(C(=O)NCCc3ccc(cc3)N3CCNCC3)c(N)c2cc1F
Show InChI InChI=1S/C22H26FN5OS/c1-2-18-17(23)13-16-19(24)20(30-22(16)27-18)21(29)26-8-7-14-3-5-15(6-4-14)28-11-9-25-10-12-28/h3-6,13,25H,2,7-12,24H2,1H3,(H,26,29)
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n/an/a<200n/an/an/an/an/an/a



VALO EARLY DISCOVERY, INC.

US Patent


Assay Description
USP25: The assay was performed in a final volume of 9 uL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HC1, pH 8.0 solution; Corning 46...


US Patent US10913753 (2021)

More data for this
Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 25


(Homo sapiens)
BDBM50279687
PNG
(CHEMBL4174196)
Show SMILES Cl.Cc1cnc2c(N)c(sc2n1)C(=O)NCCc1cc(F)c(cc1F)N1CC2CCC(C1)N2
Show InChI InChI=1S/C22H24F2N6OS.ClH/c1-11-8-27-19-18(25)20(32-22(19)28-11)21(31)26-5-4-12-6-16(24)17(7-15(12)23)30-9-13-2-3-14(10-30)29-13;/h6-8,13-14,29H,2-5,9-10,25H2,1H3,(H,26,31);1H
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n/an/a 200n/an/an/an/an/an/a



Usona Institute

Curated by ChEMBL


Assay Description
Compound was evaluated for the inhibition of dihydrofolate reductase (DHFR) derived from Chicken liver


ACS Med Chem Lett 8: 1211-1212 (2017)


Article DOI: 10.1021/acsmedchemlett.7b00449
BindingDB Entry DOI: 10.7270/Q26Q20SS
More data for this
Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 25


(Homo sapiens)
BDBM50279693
PNG
(CHEMBL4169696)
Show SMILES Cl.Cc1cnc2c(N)c(sc2n1)C(=O)NCCc1ccc(N2CC3CCC(C2)N3)c(F)c1
Show InChI InChI=1S/C22H25FN6OS.ClH/c1-12-9-26-19-18(24)20(31-22(19)27-12)21(30)25-7-6-13-2-5-17(16(23)8-13)29-10-14-3-4-15(11-29)28-14;/h2,5,8-9,14-15,28H,3-4,6-7,10-11,24H2,1H3,(H,25,30);1H
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n/an/a<200n/an/an/an/an/an/a



Usona Institute

Curated by ChEMBL


Assay Description
Compound was evaluated for the inhibition of dihydrofolate reductase (DHFR) derived from Chicken liver


ACS Med Chem Lett 8: 1211-1212 (2017)


Article DOI: 10.1021/acsmedchemlett.7b00449
BindingDB Entry DOI: 10.7270/Q26Q20SS
More data for this
Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 28


(Homo sapiens)
BDBM478023
PNG
(US10889592, Compound I-3)
Show SMILES Cc1cnc2c(N)c(sc2n1)C(=O)NCCc1ccc(N2CC3CCC(C2)N3)c(Cl)c1
Show InChI InChI=1S/C22H25ClN6OS/c1-12-9-26-19-18(24)20(31-22(19)27-12)21(30)25-7-6-13-2-5-17(16(23)8-13)29-10-14-3-4-15(11-29)28-14/h2,5,8-9,14-15,28H,3-4,6-7,10-11,24H2,1H3,(H,25,30)
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n/an/a<200n/an/an/an/an/an/a



VALO EARLY DISCOVERY, INC.

US Patent


Assay Description
USP28: Each assay was performed in a final volume of 20 μL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HCl, pH 8.0 solution; Cor...


US Patent US10889592 (2021)

More data for this
Ligand-Target Pair
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