Compile Data Set for Download or QSAR
maximum 50k data
Found 36 Enz. Inhib. hit(s) with all data for entry = 808
TargetVoltage-dependent calcium channel gamma-2 subunit(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM292056(2-Cyclobutyl-3-(7-methyl-1H-indazol-5-yl)-5-(trifl...)
Affinity DataIC50:  0.0200nMpH: 7.4Assay Description:Cell expressing the GRIA1o-CACNG8 fusion construct were grown in a monolayer in 96- or 384-well microtiter plates. They were washed with assay buffer...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetVoltage-dependent calcium channel gamma-2 subunit(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM292057(3-(7-Chloro-1H-indazol-5-yl)-2-cyclobutyl-5-(trifl...)
Affinity DataIC50:  0.0200nMpH: 7.4Assay Description:Cell expressing the GRIA1o-CACNG8 fusion construct were grown in a monolayer in 96- or 384-well microtiter plates. They were washed with assay buffer...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetVoltage-dependent calcium channel gamma-2 subunit(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM292055(7-Chloro-5-(2-cyclobutyl-5-(trifluoromethyl)-2H-py...)
Affinity DataIC50:  0.0320nMpH: 7.4Assay Description:Cell expressing the GRIA1o-CACNG8 fusion construct were grown in a monolayer in 96- or 384-well microtiter plates. They were washed with assay buffer...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetVoltage-dependent calcium channel gamma-2 subunit(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM292054(5-(2-Cyclobutyl-5-(trifluoromethyl)-2H-pyrazolo[4,...)
Affinity DataIC50:  0.0500nMpH: 7.4Assay Description:Cell expressing the GRIA1o-CACNG8 fusion construct were grown in a monolayer in 96- or 384-well microtiter plates. They were washed with assay buffer...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetVoltage-dependent calcium channel gamma-2 subunit(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM292053(3-(7-Chloro-1H-indazol-5-yl)-2-isopropyl-5-(triflu...)
Affinity DataIC50:  0.0630nMpH: 7.4Assay Description:Cell expressing the GRIA1o-CACNG8 fusion construct were grown in a monolayer in 96- or 384-well microtiter plates. They were washed with assay buffer...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetVoltage-dependent calcium channel gamma-2 subunit(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM292061(5-(Difluoromethyl)-2-isopropyl-3-(7-methyl-1H-inda...)
Affinity DataIC50:  0.100nMpH: 7.4Assay Description:Cell expressing the GRIA1o-CACNG8 fusion construct were grown in a monolayer in 96- or 384-well microtiter plates. They were washed with assay buffer...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetVoltage-dependent calcium channel gamma-2 subunit(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM292037(2-Cyclopentyl-3-(7-methyl-1H-indazol-5-yl)-5-(trif...)
Affinity DataIC50:  0.126nMpH: 7.4Assay Description:Cell expressing the GRIA1o-CACNG8 fusion construct were grown in a monolayer in 96- or 384-well microtiter plates. They were washed with assay buffer...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetVoltage-dependent calcium channel gamma-2 subunit(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM292065(5,7-Bis(difluoromethyl)-2-isopropyl-3-(7-methyl-1H...)
Affinity DataIC50:  0.158nMpH: 7.4Assay Description:Cell expressing the GRIA1o-CACNG8 fusion construct were grown in a monolayer in 96- or 384-well microtiter plates. They were washed with assay buffer...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetVoltage-dependent calcium channel gamma-2 subunit(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM292052(2-Isopropyl-3-(7-methyl-1H-indazol-5-yl)-5-(triflu...)
Affinity DataIC50:  0.251nMpH: 7.4Assay Description:Cell expressing the GRIA1o-CACNG8 fusion construct were grown in a monolayer in 96- or 384-well microtiter plates. They were washed with assay buffer...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetVoltage-dependent calcium channel gamma-2 subunit(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM292051(7-Chloro-5-(2-isopropyl-5-(trifluoromethyl)-2H-pyr...)
Affinity DataIC50:  0.251nMpH: 7.4Assay Description:Cell expressing the GRIA1o-CACNG8 fusion construct were grown in a monolayer in 96- or 384-well microtiter plates. They were washed with assay buffer...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetVoltage-dependent calcium channel gamma-2 subunit(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM292045(3-(7-Chloro-1H-indazol-5-yl)-2-methyl-5-(trifluoro...)
Affinity DataIC50:  0.316nMpH: 7.4Assay Description:Cell expressing the GRIA1o-CACNG8 fusion construct were grown in a monolayer in 96- or 384-well microtiter plates. They were washed with assay buffer...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetVoltage-dependent calcium channel gamma-2 subunit(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM292050(5-(2-Isopropyl-5-(trifluoromethyl)-2H-pyrazolo[4,3...)
Affinity DataIC50:  0.398nMpH: 7.4Assay Description:Cell expressing the GRIA1o-CACNG8 fusion construct were grown in a monolayer in 96- or 384-well microtiter plates. They were washed with assay buffer...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetVoltage-dependent calcium channel gamma-2 subunit(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM292049(3-(7-Chloro-1H-indazol-5-yl)-2-ethyl-5-(trifluorom...)
Affinity DataIC50:  0.398nMpH: 7.4Assay Description:Cell expressing the GRIA1o-CACNG8 fusion construct were grown in a monolayer in 96- or 384-well microtiter plates. They were washed with assay buffer...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetVoltage-dependent calcium channel gamma-2 subunit(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM292062(7-Chloro-5-(5-(difluoromethyl)-2-isopropyl-2H-pyra...)
Affinity DataIC50:  0.398nMpH: 7.4Assay Description:Cell expressing the GRIA1o-CACNG8 fusion construct were grown in a monolayer in 96- or 384-well microtiter plates. They were washed with assay buffer...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetVoltage-dependent calcium channel gamma-2 subunit(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM292041(2-Cyclobutyl-3-(1H-indazol-5-yl)-5-(trifluoromethy...)
Affinity DataIC50:  0.631nMpH: 7.4Assay Description:Cell expressing the GRIA1o-CACNG8 fusion construct were grown in a monolayer in 96- or 384-well microtiter plates. They were washed with assay buffer...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetVoltage-dependent calcium channel gamma-2 subunit(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM292060(3-(7-Chloro-1H-indazol-5-yl)-2-(difluoromethyl)-5-...)
Affinity DataIC50:  0.631nMpH: 7.4Assay Description:Cell expressing the GRIA1o-CACNG8 fusion construct were grown in a monolayer in 96- or 384-well microtiter plates. They were washed with assay buffer...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetVoltage-dependent calcium channel gamma-2 subunit(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM292059(2-(Difluoromethyl)-3-(7-methyl-1H-indazol-5-yl)-5-...)
Affinity DataIC50:  0.631nMpH: 7.4Assay Description:Cell expressing the GRIA1o-CACNG8 fusion construct were grown in a monolayer in 96- or 384-well microtiter plates. They were washed with assay buffer...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetVoltage-dependent calcium channel gamma-2 subunit(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM292048(2-Ethyl-3-(7-methyl-1H-indazol-5-yl)-5-(trifluorom...)
Affinity DataIC50:  0.794nMpH: 7.4Assay Description:Cell expressing the GRIA1o-CACNG8 fusion construct were grown in a monolayer in 96- or 384-well microtiter plates. They were washed with assay buffer...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetVoltage-dependent calcium channel gamma-2 subunit(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM292044(2-Methyl-3-(7-methyl-1H-indazol-5-yl)-5-(trifluoro...)
Affinity DataIC50:  1nMpH: 7.4Assay Description:Cell expressing the GRIA1o-CACNG8 fusion construct were grown in a monolayer in 96- or 384-well microtiter plates. They were washed with assay buffer...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetVoltage-dependent calcium channel gamma-2 subunit(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM292032(5-[2-(Difluoromethyl)-5-(trifluoromethyl)pyrazolo[...)
Affinity DataIC50:  1nMpH: 7.4Assay Description:Cell expressing the GRIA1o-CACNG8 fusion construct were grown in a monolayer in 96- or 384-well microtiter plates. They were washed with assay buffer...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetVoltage-dependent calcium channel gamma-2 subunit(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM292038(5-(2-Phenyl-5-(trifluoromethyl)-2H-pyrazolo[4,3-b]...)
Affinity DataIC50:  1.58nMpH: 7.4Assay Description:Cell expressing the GRIA1o-CACNG8 fusion construct were grown in a monolayer in 96- or 384-well microtiter plates. They were washed with assay buffer...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetVoltage-dependent calcium channel gamma-2 subunit(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM292047(7-Chloro-5-(2-ethyl-5-(trifluoromethyl)-2H-pyrazol...)
Affinity DataIC50:  2.51nMpH: 7.4Assay Description:Cell expressing the GRIA1o-CACNG8 fusion construct were grown in a monolayer in 96- or 384-well microtiter plates. They were washed with assay buffer...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetVoltage-dependent calcium channel gamma-2 subunit(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM292058(7-Chloro-5-(2-(difluoromethyl)-5-(trifluoromethyl)...)
Affinity DataIC50:  2.51nMpH: 7.4Assay Description:Cell expressing the GRIA1o-CACNG8 fusion construct were grown in a monolayer in 96- or 384-well microtiter plates. They were washed with assay buffer...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetVoltage-dependent calcium channel gamma-2 subunit(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM292040(3-(1H-Indazol-5-yl)-2-phenyl-5-(trifluoromethyl)-2...)
Affinity DataIC50:  3.16nMpH: 7.4Assay Description:Cell expressing the GRIA1o-CACNG8 fusion construct were grown in a monolayer in 96- or 384-well microtiter plates. They were washed with assay buffer...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetVoltage-dependent calcium channel gamma-2 subunit(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM292046(5-(2-Ethyl-5-(trifluoromethyl)-2H-pyrazolo[4,3-b]p...)
Affinity DataIC50:  5.01nMpH: 7.4Assay Description:Cell expressing the GRIA1o-CACNG8 fusion construct were grown in a monolayer in 96- or 384-well microtiter plates. They were washed with assay buffer...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetVoltage-dependent calcium channel gamma-2 subunit(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM292039(5-(2-Phenyl-5-(trifluoromethyl)-2H-pyrazolo[4,3-b]...)
Affinity DataIC50:  6.31nMpH: 7.4Assay Description:Cell expressing the GRIA1o-CACNG8 fusion construct were grown in a monolayer in 96- or 384-well microtiter plates. They were washed with assay buffer...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetVoltage-dependent calcium channel gamma-2 subunit(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM292031(7-Methyl-5-(2-methyl-5-(trifluoromethyl)-2H-pyrazo...)
Affinity DataIC50:  12.6nMpH: 7.4Assay Description:Cell expressing the GRIA1o-CACNG8 fusion construct were grown in a monolayer in 96- or 384-well microtiter plates. They were washed with assay buffer...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetVoltage-dependent calcium channel gamma-2 subunit(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM292036(5-(2-Cyclopentyl-5-(trifluoromethyl)-2H-pyrazolo[4...)
Affinity DataIC50:  15.8nMpH: 7.4Assay Description:Cell expressing the GRIA1o-CACNG8 fusion construct were grown in a monolayer in 96- or 384-well microtiter plates. They were washed with assay buffer...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetVoltage-dependent calcium channel gamma-2 subunit(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM292034(5-(2-Isopropyl-5-(trifluoromethyl)-2H-pyrazolo[4,3...)
Affinity DataIC50:  25.1nMpH: 7.4Assay Description:Cell expressing the GRIA1o-CACNG8 fusion construct were grown in a monolayer in 96- or 384-well microtiter plates. They were washed with assay buffer...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetVoltage-dependent calcium channel gamma-2 subunit(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM292064(3-(7-Chloro-1H-indazol-5-yl)-2-isopropyl-pyrazolo[...)
Affinity DataIC50:  63.1nMpH: 7.4Assay Description:Cell expressing the GRIA1o-CACNG8 fusion construct were grown in a monolayer in 96- or 384-well microtiter plates. They were washed with assay buffer...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetVoltage-dependent calcium channel gamma-2 subunit(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM292033(5-(2-Ethyl-5-(trifluoromethyl)-2H-pyrazolo[4,3-b]p...)
Affinity DataIC50:  100nMpH: 7.4Assay Description:Cell expressing the GRIA1o-CACNG8 fusion construct were grown in a monolayer in 96- or 384-well microtiter plates. They were washed with assay buffer...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetVoltage-dependent calcium channel gamma-2 subunit(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM292043(3-(1H-Indazol-5-yl)-2-(pyridin-2-yl)-5-(trifluorom...)
Affinity DataIC50:  126nMpH: 7.4Assay Description:Cell expressing the GRIA1o-CACNG8 fusion construct were grown in a monolayer in 96- or 384-well microtiter plates. They were washed with assay buffer...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetVoltage-dependent calcium channel gamma-2 subunit(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM292063(7-(Difluoromethyl)-2-isopropyl-3-(7-methyl-1H-inda...)
Affinity DataIC50:  126nMpH: 7.4Assay Description:Cell expressing the GRIA1o-CACNG8 fusion construct were grown in a monolayer in 96- or 384-well microtiter plates. They were washed with assay buffer...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetVoltage-dependent calcium channel gamma-2 subunit(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM292035(5-(2-(Cyclobutylmethyl)-5-(trifluoromethyl)-2H-pyr...)
Affinity DataIC50:  126nMpH: 7.4Assay Description:Cell expressing the GRIA1o-CACNG8 fusion construct were grown in a monolayer in 96- or 384-well microtiter plates. They were washed with assay buffer...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetVoltage-dependent calcium channel gamma-2 subunit(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM292030(5-(2-Methyl-5-(trifluoromethyl)-2H-pyrazolo[4,3-b]...)
Affinity DataIC50:  316nMpH: 7.4Assay Description:Cell expressing the GRIA1o-CACNG8 fusion construct were grown in a monolayer in 96- or 384-well microtiter plates. They were washed with assay buffer...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetVoltage-dependent calcium channel gamma-2 subunit(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM292042(3-(1H-Indazol-5-yl)-2-(2-methoxyethyl)-5-(trifluor...)
Affinity DataIC50:  794nMpH: 7.4Assay Description:Cell expressing the GRIA1o-CACNG8 fusion construct were grown in a monolayer in 96- or 384-well microtiter plates. They were washed with assay buffer...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent