Compile Data Set for Download or QSAR
maximum 50k data
Found 9 Enz. Inhib. hit(s) with all data for entry = 1020
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
The University Of Pittsburgh—Of The Commonwealth System Of Higher Education

US Patent
LigandPNGBDBM303149(US10137210, Example [N-methyl-11C]6-MeO-BTA-2)
Affinity DataKi:  2.30nMAssay Description:Initial competitive binding studies using [3H]CG and synthetic Aβ(1-40) were conducted to determine if CG, ThS and ThT bound to the same site(s)...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
The University Of Pittsburgh—Of The Commonwealth System Of Higher Education

US Patent
LigandPNGBDBM303166(US10137210, Example 00026)
Affinity DataKi:  3.22nMAssay Description:Initial competitive binding studies using [3H]CG and synthetic Aβ(1-40) were conducted to determine if CG, ThS and ThT bound to the same site(s)...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
The University Of Pittsburgh—Of The Commonwealth System Of Higher Education

US Patent
LigandPNGBDBM303164(US10137210, Example 00024)
Affinity DataKi:  4.94nMAssay Description:Initial competitive binding studies using [3H]CG and synthetic Aβ(1-40) were conducted to determine if CG, ThS and ThT bound to the same site(s)...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
The University Of Pittsburgh—Of The Commonwealth System Of Higher Education

US Patent
LigandPNGBDBM303148(US10137210, Example [N-methyl-11C]6-MeO-BTA-1)
Affinity DataKi:  5.70nMAssay Description:Initial competitive binding studies using [3H]CG and synthetic Aβ(1-40) were conducted to determine if CG, ThS and ThT bound to the same site(s)...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
The University Of Pittsburgh—Of The Commonwealth System Of Higher Education

US Patent
LigandPNGBDBM303156(US10137210, Example 00023)
Affinity DataKi:  8.32nMAssay Description:Initial competitive binding studies using [3H]CG and synthetic Aβ(1-40) were conducted to determine if CG, ThS and ThT bound to the same site(s)...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
The University Of Pittsburgh—Of The Commonwealth System Of Higher Education

US Patent
LigandPNGBDBM50109052((4-Benzothiazol-2-yl-phenyl)-methyl-amine | 4-(ben...)
Affinity DataKi:  9.60nMAssay Description:Initial competitive binding studies using [3H]CG and synthetic Aβ(1-40) were conducted to determine if CG, ThS and ThT bound to the same site(s)...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
The University Of Pittsburgh—Of The Commonwealth System Of Higher Education

US Patent
LigandPNGBDBM303165(US10137210, Example 00025)
Affinity DataKi:  11.1nMAssay Description:Initial competitive binding studies using [3H]CG and synthetic Aβ(1-40) were conducted to determine if CG, ThS and ThT bound to the same site(s)...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
The University Of Pittsburgh—Of The Commonwealth System Of Higher Education

US Patent
LigandPNGBDBM50109051(CHEMBL330529 | Methyl-[4-(6-methyl-benzothiazol-2-...)
Affinity DataKi:  21nMAssay Description:Initial competitive binding studies using [3H]CG and synthetic Aβ(1-40) were conducted to determine if CG, ThS and ThT bound to the same site(s)...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
The University Of Pittsburgh—Of The Commonwealth System Of Higher Education

US Patent
LigandPNGBDBM50052701(2-(4-Aminophenyl)-6-methoxybenzothiazole | 4-(6-Me...)
Affinity DataKi:  30nMAssay Description:Initial competitive binding studies using [3H]CG and synthetic Aβ(1-40) were conducted to determine if CG, ThS and ThT bound to the same site(s)...More data for this Ligand-Target Pair
In DepthDetails US Patent