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maximum 50k data
Found 76 Enz. Inhib. hit(s) with all data for entry = 1123
TargetHistone deacetylase 6(Homo sapiens (Human))
Karus Therapeutics

US Patent
LigandPNGBDBM310701(US10150763, Example A)
Affinity DataIC50:  1.76nMAssay Description:The assay is described in WO2008/062201.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistone deacetylase 1(Homo sapiens (Human))
Karus Therapeutics

US Patent
LigandPNGBDBM310701(US10150763, Example A)
Affinity DataIC50:  226nMAssay Description:The assay is described in WO2008/062201.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistone deacetylase 1(Homo sapiens (Human))
Karus Therapeutics

US Patent
LigandPNGBDBM310702(N-Hydroxy-7-[(3-methyl-1,2,4-thiadiazol-5-yl)(pyri...)
Affinity DataIC50: <500nMAssay Description:The assay is described in WO2008/062201.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistone deacetylase 6(Homo sapiens (Human))
Karus Therapeutics

US Patent
LigandPNGBDBM310702(N-Hydroxy-7-[(3-methyl-1,2,4-thiadiazol-5-yl)(pyri...)
Affinity DataIC50: <500nMAssay Description:The assay is described in WO2008/062201.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistone deacetylase 1(Homo sapiens (Human))
Karus Therapeutics

US Patent
LigandPNGBDBM310703(N-Hydroxy-7-((3-methyl-1,2,4-oxadiazol-5-yl)(pyrid...)
Affinity DataIC50: <500nMAssay Description:The assay is described in WO2008/062201.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistone deacetylase 6(Homo sapiens (Human))
Karus Therapeutics

US Patent
LigandPNGBDBM310703(N-Hydroxy-7-((3-methyl-1,2,4-oxadiazol-5-yl)(pyrid...)
Affinity DataIC50: <500nMAssay Description:The assay is described in WO2008/062201.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistone deacetylase 6(Homo sapiens (Human))
Karus Therapeutics

US Patent
LigandPNGBDBM310704(N-Hydroxy-8-((3-methyl-1,2,4-oxadiazol-5-yl)(pyrid...)
Affinity DataIC50: <500nMAssay Description:The assay is described in WO2008/062201.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistone deacetylase 1(Homo sapiens (Human))
Karus Therapeutics

US Patent
LigandPNGBDBM310705(N-Hydroxy-7-((1-methyl-1H-pyrazol-3-yl)(pyridin-2-...)
Affinity DataIC50: <500nMAssay Description:The assay is described in WO2008/062201.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistone deacetylase 6(Homo sapiens (Human))
Karus Therapeutics

US Patent
LigandPNGBDBM310705(N-Hydroxy-7-((1-methyl-1H-pyrazol-3-yl)(pyridin-2-...)
Affinity DataIC50: <500nMAssay Description:The assay is described in WO2008/062201.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistone deacetylase 6(Homo sapiens (Human))
Karus Therapeutics

US Patent
LigandPNGBDBM310706(N-Hydroxy-8-((1-methyl-1H-pyrazol-3-yl)(pyridin-2-...)
Affinity DataIC50: <500nMAssay Description:The assay is described in WO2008/062201.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistone deacetylase 1(Homo sapiens (Human))
Karus Therapeutics

US Patent
LigandPNGBDBM310707(N-Hydroxy-7-(pyridin-2-yl(1,3,4-thiadiazol-2-yl)am...)
Affinity DataIC50: <500nMAssay Description:The assay is described in WO2008/062201.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistone deacetylase 6(Homo sapiens (Human))
Karus Therapeutics

US Patent
LigandPNGBDBM310707(N-Hydroxy-7-(pyridin-2-yl(1,3,4-thiadiazol-2-yl)am...)
Affinity DataIC50: <500nMAssay Description:The assay is described in WO2008/062201.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistone deacetylase 6(Homo sapiens (Human))
Karus Therapeutics

US Patent
LigandPNGBDBM310708(N-Hydroxy-8-(pyridin-2-yl(1,3,4-thiadiazol-2-yl)am...)
Affinity DataIC50: <500nMAssay Description:The assay is described in WO2008/062201.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistone deacetylase 6(Homo sapiens (Human))
Karus Therapeutics

US Patent
LigandPNGBDBM310709(N-Hydroxy-7-((5-methyl-1,3,4-thiadiazol-2-yl)(pyri...)
Affinity DataIC50: <500nMAssay Description:The assay is described in WO2008/062201.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistone deacetylase 6(Homo sapiens (Human))
Karus Therapeutics

US Patent
LigandPNGBDBM310710(N-Hydroxy-8-((5-methyl-1,3,4-thiadiazol-2-yl)(pyri...)
Affinity DataIC50: <500nMAssay Description:The assay is described in WO2008/062201.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistone deacetylase 1(Homo sapiens (Human))
Karus Therapeutics

US Patent
LigandPNGBDBM310711(7-(Benzo[d]oxazol-2-yl(pyridin-2-yl)amino)-N-hydro...)
Affinity DataIC50: <500nMAssay Description:The assay is described in WO2008/062201.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistone deacetylase 6(Homo sapiens (Human))
Karus Therapeutics

US Patent
LigandPNGBDBM310711(7-(Benzo[d]oxazol-2-yl(pyridin-2-yl)amino)-N-hydro...)
Affinity DataIC50: <500nMAssay Description:The assay is described in WO2008/062201.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistone deacetylase 6(Homo sapiens (Human))
Karus Therapeutics

US Patent
LigandPNGBDBM310712(8-(Benzo[d]oxazol-2-yl(pyridin-2-yl)amino)-N-hydro...)
Affinity DataIC50: <500nMAssay Description:The assay is described in WO2008/062201.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistone deacetylase 6(Homo sapiens (Human))
Karus Therapeutics

US Patent
LigandPNGBDBM310713(N-Hydroxy-7-((1-methyl-1H-benzo[d]imidazol-2-yl)(p...)
Affinity DataIC50: <500nMAssay Description:The assay is described in WO2008/062201.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistone deacetylase 6(Homo sapiens (Human))
Karus Therapeutics

US Patent
LigandPNGBDBM310714(N-Hydroxy-8-((1-methyl-1H-benzo[d]imidazol-2-yl)(p...)
Affinity DataIC50: <500nMAssay Description:The assay is described in WO2008/062201.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistone deacetylase 6(Homo sapiens (Human))
Karus Therapeutics

US Patent
LigandPNGBDBM310715(N-Hydroxy-7-(pyridin-2-yl(1,2,4-thiadiazol-5-yl)am...)
Affinity DataIC50: <500nMAssay Description:The assay is described in WO2008/062201.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistone deacetylase 6(Homo sapiens (Human))
Karus Therapeutics

US Patent
LigandPNGBDBM310716(N-Hydroxy-8-(pyridin-2-yl(1,2,4-thiadiazol-5-yl)am...)
Affinity DataIC50: <500nMAssay Description:The assay is described in WO2008/062201.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistone deacetylase 6(Homo sapiens (Human))
Karus Therapeutics

US Patent
LigandPNGBDBM310717(7-((5-Fluoropyridin-2-yl)(3-methyl-1,2,4-oxadiazol...)
Affinity DataIC50: <500nMAssay Description:The assay is described in WO2008/062201.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistone deacetylase 6(Homo sapiens (Human))
Karus Therapeutics

US Patent
LigandPNGBDBM310718(8-((5-Fluoropyridin-2-yl)(3-methyl-1,2,4-oxadiazol...)
Affinity DataIC50: <500nMAssay Description:The assay is described in WO2008/062201.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistone deacetylase 6(Homo sapiens (Human))
Karus Therapeutics

US Patent
LigandPNGBDBM310719(7-((5-Fluoropyridin-2-yl)(1-methyl-1H-benzo[d]imid...)
Affinity DataIC50: <500nMAssay Description:The assay is described in WO2008/062201.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistone deacetylase 6(Homo sapiens (Human))
Karus Therapeutics

US Patent
LigandPNGBDBM310720(8-((5-Fluoropyridin-2-yl)(1-methyl-1H-benzo[d]imid...)
Affinity DataIC50: <500nMAssay Description:The assay is described in WO2008/062201.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistone deacetylase 6(Homo sapiens (Human))
Karus Therapeutics

US Patent
LigandPNGBDBM310721(7-((5-Fluoropyridin-2-yl)(1-methyl-1H-pyrazol-3-yl...)
Affinity DataIC50: <500nMAssay Description:The assay is described in WO2008/062201.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistone deacetylase 6(Homo sapiens (Human))
Karus Therapeutics

US Patent
LigandPNGBDBM310722(8-((5-Fluoropyridin-2-yl)(1-methyl-1H-pyrazol-3-yl...)
Affinity DataIC50: <500nMAssay Description:The assay is described in WO2008/062201.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistone deacetylase 6(Homo sapiens (Human))
Karus Therapeutics

US Patent
LigandPNGBDBM310723(7-(Benzo[d]oxazol-2-yl(5-fluoropyridin-2-yl)amino)...)
Affinity DataIC50: <500nMAssay Description:The assay is described in WO2008/062201.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistone deacetylase 6(Homo sapiens (Human))
Karus Therapeutics

US Patent
LigandPNGBDBM310724(8-(Benzo[d]oxazol-2-yl(5-fluoropyridin-2-yl)amino)...)
Affinity DataIC50: <500nMAssay Description:The assay is described in WO2008/062201.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistone deacetylase 1(Homo sapiens (Human))
Karus Therapeutics

US Patent
LigandPNGBDBM310725(7-((4-(4-Fluorophenyl)pyridin-2-yl)(1-methyl-1H-py...)
Affinity DataIC50: <500nMAssay Description:The assay is described in WO2008/062201.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistone deacetylase 6(Homo sapiens (Human))
Karus Therapeutics

US Patent
LigandPNGBDBM310725(7-((4-(4-Fluorophenyl)pyridin-2-yl)(1-methyl-1H-py...)
Affinity DataIC50: <500nMAssay Description:The assay is described in WO2008/062201.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistone deacetylase 6(Homo sapiens (Human))
Karus Therapeutics

US Patent
LigandPNGBDBM310726(8-((4-(4-Fluorophenyl)pyridin-2-yl)(1-methyl-1H-py...)
Affinity DataIC50: <500nMAssay Description:The assay is described in WO2008/062201.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistone deacetylase 6(Homo sapiens (Human))
Karus Therapeutics

US Patent
LigandPNGBDBM310727(7-((5-Fluoropyridin-2-yl)(3-(trifluoromethyl)1,2,4...)
Affinity DataIC50: <500nMAssay Description:The assay is described in WO2008/062201.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistone deacetylase 6(Homo sapiens (Human))
Karus Therapeutics

US Patent
LigandPNGBDBM310728(8-((5-Fluoropyridin-2-yl)(3-(trifluoromethyl)1,2,4...)
Affinity DataIC50: <500nMAssay Description:The assay is described in WO2008/062201.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistone deacetylase 6(Homo sapiens (Human))
Karus Therapeutics

US Patent
LigandPNGBDBM310729(7-((5-Fluoropyridin-2-yl)(3-methyl-1,2,4-thiadiazo...)
Affinity DataIC50: <500nMAssay Description:The assay is described in WO2008/062201.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistone deacetylase 6(Homo sapiens (Human))
Karus Therapeutics

US Patent
LigandPNGBDBM310730(8-((5-Fluoropyridin-2-yl)(3-methyl-1,2,4-thiadiazo...)
Affinity DataIC50: <500nMAssay Description:The assay is described in WO2008/062201.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistone deacetylase 6(Homo sapiens (Human))
Karus Therapeutics

US Patent
LigandPNGBDBM310731(7-((4-(4-Fluorophenyl)pyridin-2-yl)(3-methyl-1,2,4...)
Affinity DataIC50: <500nMAssay Description:The assay is described in WO2008/062201.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistone deacetylase 6(Homo sapiens (Human))
Karus Therapeutics

US Patent
LigandPNGBDBM310732(8-((4-(4-Fluorophenyl)-pyridin-2-yl)(3-methyl-1,2,...)
Affinity DataIC50: <500nMAssay Description:The assay is described in WO2008/062201.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistone deacetylase 6(Homo sapiens (Human))
Karus Therapeutics

US Patent
LigandPNGBDBM310733(7-((5-Fluoropyridin-2-yl)(3-(trifluoromethyl)1,2,4...)
Affinity DataIC50: <500nMAssay Description:The assay is described in WO2008/062201.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistone deacetylase 6(Homo sapiens (Human))
Karus Therapeutics

US Patent
LigandPNGBDBM310734(8-((5-Fluoropyridin-2-yl)(3-(trifluoromethyl)1,2,4...)
Affinity DataIC50: <500nMAssay Description:The assay is described in WO2008/062201.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistone deacetylase 6(Homo sapiens (Human))
Karus Therapeutics

US Patent
LigandPNGBDBM310735(7-(Benzo[d]thiazol-2-yl(pyridin-2-yl)amino)-N-hydr...)
Affinity DataIC50: <500nMAssay Description:The assay is described in WO2008/062201.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistone deacetylase 6(Homo sapiens (Human))
Karus Therapeutics

US Patent
LigandPNGBDBM310736(8-(Benzo[d]thiazol-2-yl(pyridin-2-yl)amino)-N-hydr...)
Affinity DataIC50: <500nMAssay Description:The assay is described in WO2008/062201.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistone deacetylase 6(Homo sapiens (Human))
Karus Therapeutics

US Patent
LigandPNGBDBM310737(N-Hydroxy-7-(pyridin-2-yl(thiazol-2-yl)amino)hepta...)
Affinity DataIC50: <500nMAssay Description:The assay is described in WO2008/062201.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistone deacetylase 6(Homo sapiens (Human))
Karus Therapeutics

US Patent
LigandPNGBDBM310738(US10150763, Example LL)
Affinity DataIC50: <500nMAssay Description:The assay is described in WO2008/062201.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistone deacetylase 1(Homo sapiens (Human))
Karus Therapeutics

US Patent
LigandPNGBDBM310709(N-Hydroxy-7-((5-methyl-1,3,4-thiadiazol-2-yl)(pyri...)
Affinity DataIC50:  750nMAssay Description:The assay is described in WO2008/062201.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistone deacetylase 1(Homo sapiens (Human))
Karus Therapeutics

US Patent
LigandPNGBDBM310715(N-Hydroxy-7-(pyridin-2-yl(1,2,4-thiadiazol-5-yl)am...)
Affinity DataIC50:  750nMAssay Description:The assay is described in WO2008/062201.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistone deacetylase 1(Homo sapiens (Human))
Karus Therapeutics

US Patent
LigandPNGBDBM310719(7-((5-Fluoropyridin-2-yl)(1-methyl-1H-benzo[d]imid...)
Affinity DataIC50:  750nMAssay Description:The assay is described in WO2008/062201.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistone deacetylase 1(Homo sapiens (Human))
Karus Therapeutics

US Patent
LigandPNGBDBM310733(7-((5-Fluoropyridin-2-yl)(3-(trifluoromethyl)1,2,4...)
Affinity DataIC50:  750nMAssay Description:The assay is described in WO2008/062201.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistone deacetylase 1(Homo sapiens (Human))
Karus Therapeutics

US Patent
LigandPNGBDBM310729(7-((5-Fluoropyridin-2-yl)(3-methyl-1,2,4-thiadiazo...)
Affinity DataIC50:  750nMAssay Description:The assay is described in WO2008/062201.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
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