Compile Data Set for Download or QSAR
maximum 50k data
Found 10 Enz. Inhib. hit(s) with all data for entry = 2000
TargetEgl nine homolog 1(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM350280(2-(4-Hydroxy-2-oxo-1-(3'- (trifluoromethoxy)-[1,1'...)
Affinity DataIC50:  4.10nMAssay Description:To each well of a 384-well plate, 1 μL of test compounds in DMSO (final concentration ranging from 0.3 nM to 10 uM) were added into 20 μl o...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEgl nine homolog 1(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM350271(2-(1-(4-chlorophenyl)-4- hydroxy-2-oxo-1,2,5,7- te...)
Affinity DataIC50:  7.80nMAssay Description:To each well of a 384-well plate, 1 μL of test compounds in DMSO (final concentration ranging from 0.3 nM to 10 uM) were added into 20 μl o...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEgl nine homolog 1(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM350273(2-(4-hydroxy-2-oxo-1-phenyl- 1,2,5,7-tetrahydrofur...)
Affinity DataIC50:  8.5nMAssay Description:To each well of a 384-well plate, 1 μL of test compounds in DMSO (final concentration ranging from 0.3 nM to 10 uM) were added into 20 μl o...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEgl nine homolog 1(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM350276(2-(4-hydroxy-2-oxo-1-(m- tolyl)-1,2,5,7- tetrahydr...)
Affinity DataIC50:  8.60nMAssay Description:To each well of a 384-well plate, 1 μL of test compounds in DMSO (final concentration ranging from 0.3 nM to 10 uM) were added into 20 μl o...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEgl nine homolog 1(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM350278(2-(1-(4-cyanophenyl)-4- hydroxy-2-oxo-1,2,5,7- tet...)
Affinity DataIC50:  9.5nMAssay Description:To each well of a 384-well plate, 1 μL of test compounds in DMSO (final concentration ranging from 0.3 nM to 10 uM) were added into 20 μl o...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEgl nine homolog 1(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM350277(2-(4-hydroxy-2-oxo-1-(p- tolyl)-1,2,5,7- tetrahydr...)
Affinity DataIC50:  10nMAssay Description:To each well of a 384-well plate, 1 μL of test compounds in DMSO (final concentration ranging from 0.3 nM to 10 uM) were added into 20 μl o...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEgl nine homolog 1(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM350274(2-(4-hydroxy-1-(4- methoxyphenyl)-2-oxo- 1,2,5,7-t...)
Affinity DataIC50:  11.4nMAssay Description:To each well of a 384-well plate, 1 μL of test compounds in DMSO (final concentration ranging from 0.3 nM to 10 uM) were added into 20 μl o...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEgl nine homolog 1(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM350275(2-(4-hydroxy-2-oxo-1-(4- (trifluoromethoxy)phenyl)...)
Affinity DataIC50:  13.4nMAssay Description:To each well of a 384-well plate, 1 μL of test compounds in DMSO (final concentration ranging from 0.3 nM to 10 uM) were added into 20 μl o...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEgl nine homolog 1(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM350272(2-(1-(4-fluorophenyl)-4- hydroxy-2-oxo-1,2,5,7- te...)
Affinity DataIC50:  14.1nMAssay Description:To each well of a 384-well plate, 1 μL of test compounds in DMSO (final concentration ranging from 0.3 nM to 10 uM) were added into 20 μl o...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEgl nine homolog 1(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM350279(2-(4-hydroxy-1-(5- methoxypyridin-2-yl)-2-oxo- 1,2...)
Affinity DataIC50:  14.2nMAssay Description:To each well of a 384-well plate, 1 μL of test compounds in DMSO (final concentration ranging from 0.3 nM to 10 uM) were added into 20 μl o...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent