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Found 1 Enz. Inhib. hit(s) with all data for entry = 5561
TargetIsocitrate dehydrogenase [NADP] cytoplasmic [R132H](Homo sapiens (Human))
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM404661(US10344004, Test compound Table 3 | US10442772, Ex...)
Affinity DataIC50:  20nMAssay Description:IDH1 R132H catalyzes the NADPH-dependent reduction of alpha-ketoglutarate (α-KG) to (2R)-2-hydroxyglutarate (2-HG). NADPH consumption is determi...More data for this Ligand-Target Pair
In DepthDetails US Patent