Compile Data Set for Download or QSAR
maximum 50k data
Found 4 Enz. Inhib. hit(s) with all data for entry = 8686
TargetG-protein coupled receptor 6(Homo sapiens (Human))
Takeda Pharmaceutical

US Patent
LigandPNGBDBM412953(US10406157, Compound Formula 1)
Affinity DataKi:  5.5nMAssay Description:The inhibition constant (Ki) from a GPR6 competition binding assay and the IC50 values from a hERG functional assay for the compound of Formula 1 (Ex...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetG-protein coupled receptor 6(Homo sapiens (Human))
Takeda Pharmaceutical

US Patent
LigandPNGBDBM191037(US10077266, Example 149 | US10406157, Compound A |...)
Affinity DataKi:  6nMAssay Description:The inhibition constant (Ki) from a GPR6 competition binding assay and the IC50 values from a hERG functional assay for the compound of Formula 1 (Ex...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetG-protein coupled receptor 6(Homo sapiens (Human))
Takeda Pharmaceutical

US Patent
LigandPNGBDBM191037(US10077266, Example 149 | US10406157, Compound A |...)
Affinity DataIC50:  505nMAssay Description:The inhibition constant (Ki) from a GPR6 competition binding assay and the IC50 values from a hERG functional assay for the compound of Formula 1 (Ex...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetG-protein coupled receptor 6(Homo sapiens (Human))
Takeda Pharmaceutical

US Patent
LigandPNGBDBM412953(US10406157, Compound Formula 1)
Affinity DataIC50:  1.97E+3nMAssay Description:The inhibition constant (Ki) from a GPR6 competition binding assay and the IC50 values from a hERG functional assay for the compound of Formula 1 (Ex...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent