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Found 61 Enz. Inhib. hit(s) with all data for entry = 8709
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Taiho Pharmaceutical

US Patent
LigandPNGBDBM153227(US10421760, Comparative Example 12 | US8993756, 20...)
Affinity DataIC50:  0.0900nMAssay Description:JAK3: Among materials for the measurement of this inhibiting activity, a substrate peptide and a kinase protein were acquired as follows. As such a s...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Taiho Pharmaceutical

US Patent
LigandPNGBDBM413992(US10421760, Compound 1)
Affinity DataIC50: <0.300nMAssay Description:JAK3: Among materials for the measurement of this inhibiting activity, a substrate peptide and a kinase protein were acquired as follows. As such a s...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Taiho Pharmaceutical

US Patent
LigandPNGBDBM414003(US10421760, Compound 14)
Affinity DataIC50: <0.300nMAssay Description:JAK3: Among materials for the measurement of this inhibiting activity, a substrate peptide and a kinase protein were acquired as follows. As such a s...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Taiho Pharmaceutical

US Patent
LigandPNGBDBM413999(US10421760, Compound 9)
Affinity DataIC50: <0.300nMAssay Description:JAK3: Among materials for the measurement of this inhibiting activity, a substrate peptide and a kinase protein were acquired as follows. As such a s...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Taiho Pharmaceutical

US Patent
LigandPNGBDBM413996(US10421760, Compound 5)
Affinity DataIC50: <0.300nMAssay Description:JAK3: Among materials for the measurement of this inhibiting activity, a substrate peptide and a kinase protein were acquired as follows. As such a s...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Taiho Pharmaceutical

US Patent
LigandPNGBDBM414002(US10421760, Compound 13)
Affinity DataIC50: <0.300nMAssay Description:JAK3: Among materials for the measurement of this inhibiting activity, a substrate peptide and a kinase protein were acquired as follows. As such a s...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Taiho Pharmaceutical

US Patent
LigandPNGBDBM413993(US10421760, Compound 2)
Affinity DataIC50: <0.300nMAssay Description:JAK3: Among materials for the measurement of this inhibiting activity, a substrate peptide and a kinase protein were acquired as follows. As such a s...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Taiho Pharmaceutical

US Patent
LigandPNGBDBM413998(US10421760, Compound 8)
Affinity DataIC50: <0.300nMAssay Description:JAK3: Among materials for the measurement of this inhibiting activity, a substrate peptide and a kinase protein were acquired as follows. As such a s...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Taiho Pharmaceutical

US Patent
LigandPNGBDBM413994(US10421760, Compound 3)
Affinity DataIC50: <0.300nMAssay Description:JAK3: Among materials for the measurement of this inhibiting activity, a substrate peptide and a kinase protein were acquired as follows. As such a s...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Taiho Pharmaceutical

US Patent
LigandPNGBDBM413997(US10421760, Compound 7)
Affinity DataIC50: <0.300nMAssay Description:JAK3: Among materials for the measurement of this inhibiting activity, a substrate peptide and a kinase protein were acquired as follows. As such a s...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Taiho Pharmaceutical

US Patent
LigandPNGBDBM414004(US10421760, Compound 15)
Affinity DataIC50:  0.330nMAssay Description:JAK3: Among materials for the measurement of this inhibiting activity, a substrate peptide and a kinase protein were acquired as follows. As such a s...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Taiho Pharmaceutical

US Patent
LigandPNGBDBM414001(US10421760, Compound 12)
Affinity DataIC50:  0.350nMAssay Description:JAK3: Among materials for the measurement of this inhibiting activity, a substrate peptide and a kinase protein were acquired as follows. As such a s...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Taiho Pharmaceutical

US Patent
LigandPNGBDBM413995(US10421760, Compound 4)
Affinity DataIC50:  0.420nMAssay Description:JAK3: Among materials for the measurement of this inhibiting activity, a substrate peptide and a kinase protein were acquired as follows. As such a s...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Taiho Pharmaceutical

US Patent
LigandPNGBDBM414000(US10421760, Compound 10)
Affinity DataIC50:  0.680nMAssay Description:JAK3: Among materials for the measurement of this inhibiting activity, a substrate peptide and a kinase protein were acquired as follows. As such a s...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Taiho Pharmaceutical

US Patent
LigandPNGBDBM414005(US10421760, Compound 16)
Affinity DataIC50:  0.770nMAssay Description:JAK3: Among materials for the measurement of this inhibiting activity, a substrate peptide and a kinase protein were acquired as follows. As such a s...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Taiho Pharmaceutical

US Patent
LigandPNGBDBM414010(US10421760, Comparative Example 11(a) | US10421760...)
Affinity DataIC50:  19nMAssay Description:JAK3: Among materials for the measurement of this inhibiting activity, a substrate peptide and a kinase protein were acquired as follows. As such a s...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Taiho Pharmaceutical

US Patent
LigandPNGBDBM414010(US10421760, Comparative Example 11(a) | US10421760...)
Affinity DataIC50:  21nMAssay Description:JAK3: Among materials for the measurement of this inhibiting activity, a substrate peptide and a kinase protein were acquired as follows. As such a s...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Taiho Pharmaceutical

US Patent
LigandPNGBDBM414008(US10421760, Comparative Example 8)
Affinity DataIC50:  21.4nMAssay Description:JAK3: Among materials for the measurement of this inhibiting activity, a substrate peptide and a kinase protein were acquired as follows. As such a s...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Taiho Pharmaceutical

US Patent
LigandPNGBDBM414007(US10421760, Comparative Example 2)
Affinity DataIC50:  27nMAssay Description:JAK3: Among materials for the measurement of this inhibiting activity, a substrate peptide and a kinase protein were acquired as follows. As such a s...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Taiho Pharmaceutical

US Patent
LigandPNGBDBM414006(US10421760, Comparative Example 1)
Affinity DataIC50:  44nMAssay Description:JAK3: Among materials for the measurement of this inhibiting activity, a substrate peptide and a kinase protein were acquired as follows. As such a s...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Taiho Pharmaceutical

US Patent
LigandPNGBDBM414009(US10421760, Comparative Example 10)
Affinity DataIC50:  125nMAssay Description:JAK3: Among materials for the measurement of this inhibiting activity, a substrate peptide and a kinase protein were acquired as follows. As such a s...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Taiho Pharmaceutical

US Patent
LigandPNGBDBM414009(US10421760, Comparative Example 10)
Affinity DataIC50:  166nMAssay Description:JAK 2: Among materials for the measurement of this inhibiting activity, a substrate peptide and a kinase protein were acquired as follows. As such a ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Taiho Pharmaceutical

US Patent
LigandPNGBDBM413997(US10421760, Compound 7)
Affinity DataIC50:  330nMAssay Description:JAK 2: Among materials for the measurement of this inhibiting activity, a substrate peptide and a kinase protein were acquired as follows. As such a ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
Taiho Pharmaceutical

US Patent
LigandPNGBDBM414009(US10421760, Comparative Example 10)
Affinity DataIC50:  414nMAssay Description:JAK 1: Among materials for the measurement of this inhibiting activity, a substrate peptide and a kinase protein were acquired as follows. As such a ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Taiho Pharmaceutical

US Patent
LigandPNGBDBM413996(US10421760, Compound 5)
Affinity DataIC50:  430nMAssay Description:JAK 2: Among materials for the measurement of this inhibiting activity, a substrate peptide and a kinase protein were acquired as follows. As such a ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Taiho Pharmaceutical

US Patent
LigandPNGBDBM413998(US10421760, Compound 8)
Affinity DataIC50:  430nMAssay Description:JAK 2: Among materials for the measurement of this inhibiting activity, a substrate peptide and a kinase protein were acquired as follows. As such a ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
Taiho Pharmaceutical

US Patent
LigandPNGBDBM413997(US10421760, Compound 7)
Affinity DataIC50:  440nMAssay Description:JAK 1: Among materials for the measurement of this inhibiting activity, a substrate peptide and a kinase protein were acquired as follows. As such a ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Taiho Pharmaceutical

US Patent
LigandPNGBDBM414004(US10421760, Compound 15)
Affinity DataIC50:  450nMAssay Description:JAK 2: Among materials for the measurement of this inhibiting activity, a substrate peptide and a kinase protein were acquired as follows. As such a ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Taiho Pharmaceutical

US Patent
LigandPNGBDBM413992(US10421760, Compound 1)
Affinity DataIC50:  470nMAssay Description:JAK 2: Among materials for the measurement of this inhibiting activity, a substrate peptide and a kinase protein were acquired as follows. As such a ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Taiho Pharmaceutical

US Patent
LigandPNGBDBM413993(US10421760, Compound 2)
Affinity DataIC50:  480nMAssay Description:JAK 2: Among materials for the measurement of this inhibiting activity, a substrate peptide and a kinase protein were acquired as follows. As such a ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Taiho Pharmaceutical

US Patent
LigandPNGBDBM414002(US10421760, Compound 13)
Affinity DataIC50:  490nMAssay Description:JAK 2: Among materials for the measurement of this inhibiting activity, a substrate peptide and a kinase protein were acquired as follows. As such a ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Taiho Pharmaceutical

US Patent
LigandPNGBDBM414007(US10421760, Comparative Example 2)
Affinity DataIC50:  600nMAssay Description:JAK 2: Among materials for the measurement of this inhibiting activity, a substrate peptide and a kinase protein were acquired as follows. As such a ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Taiho Pharmaceutical

US Patent
LigandPNGBDBM414000(US10421760, Compound 10)
Affinity DataIC50:  660nMAssay Description:JAK 2: Among materials for the measurement of this inhibiting activity, a substrate peptide and a kinase protein were acquired as follows. As such a ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
Taiho Pharmaceutical

US Patent
LigandPNGBDBM413996(US10421760, Compound 5)
Affinity DataIC50:  720nMAssay Description:JAK 1: Among materials for the measurement of this inhibiting activity, a substrate peptide and a kinase protein were acquired as follows. As such a ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
Taiho Pharmaceutical

US Patent
LigandPNGBDBM414007(US10421760, Comparative Example 2)
Affinity DataIC50:  730nMAssay Description:JAK 1: Among materials for the measurement of this inhibiting activity, a substrate peptide and a kinase protein were acquired as follows. As such a ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Taiho Pharmaceutical

US Patent
LigandPNGBDBM413994(US10421760, Compound 3)
Affinity DataIC50:  850nMAssay Description:JAK 2: Among materials for the measurement of this inhibiting activity, a substrate peptide and a kinase protein were acquired as follows. As such a ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Taiho Pharmaceutical

US Patent
LigandPNGBDBM414001(US10421760, Compound 12)
Affinity DataIC50:  870nMAssay Description:JAK 2: Among materials for the measurement of this inhibiting activity, a substrate peptide and a kinase protein were acquired as follows. As such a ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
Taiho Pharmaceutical

US Patent
LigandPNGBDBM413992(US10421760, Compound 1)
Affinity DataIC50:  880nMAssay Description:JAK 1: Among materials for the measurement of this inhibiting activity, a substrate peptide and a kinase protein were acquired as follows. As such a ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
Taiho Pharmaceutical

US Patent
LigandPNGBDBM414006(US10421760, Comparative Example 1)
Affinity DataIC50:  880nMAssay Description:JAK 1: Among materials for the measurement of this inhibiting activity, a substrate peptide and a kinase protein were acquired as follows. As such a ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Taiho Pharmaceutical

US Patent
LigandPNGBDBM414010(US10421760, Comparative Example 11(a) | US10421760...)
Affinity DataIC50:  880nMAssay Description:JAK 2: Among materials for the measurement of this inhibiting activity, a substrate peptide and a kinase protein were acquired as follows. As such a ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Taiho Pharmaceutical

US Patent
LigandPNGBDBM413999(US10421760, Compound 9)
Affinity DataIC50:  880nMAssay Description:JAK 2: Among materials for the measurement of this inhibiting activity, a substrate peptide and a kinase protein were acquired as follows. As such a ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
Taiho Pharmaceutical

US Patent
LigandPNGBDBM413993(US10421760, Compound 2)
Affinity DataIC50:  900nMAssay Description:JAK 1: Among materials for the measurement of this inhibiting activity, a substrate peptide and a kinase protein were acquired as follows. As such a ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Taiho Pharmaceutical

US Patent
LigandPNGBDBM414005(US10421760, Compound 16)
Affinity DataIC50:  1.00E+3nMAssay Description:JAK 2: Among materials for the measurement of this inhibiting activity, a substrate peptide and a kinase protein were acquired as follows. As such a ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Taiho Pharmaceutical

US Patent
LigandPNGBDBM153227(US10421760, Comparative Example 12 | US8993756, 20...)
Affinity DataIC50: >1.00E+3nMAssay Description:JAK 2: Among materials for the measurement of this inhibiting activity, a substrate peptide and a kinase protein were acquired as follows. As such a ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
Taiho Pharmaceutical

US Patent
LigandPNGBDBM153227(US10421760, Comparative Example 12 | US8993756, 20...)
Affinity DataIC50: >1.00E+3nMAssay Description:JAK 1: Among materials for the measurement of this inhibiting activity, a substrate peptide and a kinase protein were acquired as follows. As such a ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Taiho Pharmaceutical

US Patent
LigandPNGBDBM414006(US10421760, Comparative Example 1)
Affinity DataIC50:  1.10E+3nMAssay Description:JAK 2: Among materials for the measurement of this inhibiting activity, a substrate peptide and a kinase protein were acquired as follows. As such a ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Taiho Pharmaceutical

US Patent
LigandPNGBDBM414003(US10421760, Compound 14)
Affinity DataIC50:  1.20E+3nMAssay Description:JAK 2: Among materials for the measurement of this inhibiting activity, a substrate peptide and a kinase protein were acquired as follows. As such a ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Taiho Pharmaceutical

US Patent
LigandPNGBDBM413995(US10421760, Compound 4)
Affinity DataIC50:  1.30E+3nMAssay Description:JAK 2: Among materials for the measurement of this inhibiting activity, a substrate peptide and a kinase protein were acquired as follows. As such a ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
Taiho Pharmaceutical

US Patent
LigandPNGBDBM413998(US10421760, Compound 8)
Affinity DataIC50:  1.40E+3nMAssay Description:JAK 1: Among materials for the measurement of this inhibiting activity, a substrate peptide and a kinase protein were acquired as follows. As such a ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
Taiho Pharmaceutical

US Patent
LigandPNGBDBM413994(US10421760, Compound 3)
Affinity DataIC50:  1.50E+3nMAssay Description:JAK 1: Among materials for the measurement of this inhibiting activity, a substrate peptide and a kinase protein were acquired as follows. As such a ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
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