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Found 100 Enz. Inhib. hit(s) with all data for entry = 8943
TargetGamma-aminobutyric acid type B receptor subunit 2(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM430521(N-(3-{5-[(1S)-1-(4-chlorophenyl)ethyl]-3-cycloprop...)
Affinity DataEC50:  51nMAssay Description:The composition of the assay mixtures [in a final volume of 200 μL in 96-well U-bottom plates (Greiner) was as follows: 50 mM Tris-HCl buffer, p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGamma-aminobutyric acid type B receptor subunit 2(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM430522(US10556914, Example 2)
Affinity DataEC50: >1.00E+4nMAssay Description:The composition of the assay mixtures [in a final volume of 200 μL in 96-well U-bottom plates (Greiner) was as follows: 50 mM Tris-HCl buffer, p...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGamma-aminobutyric acid type B receptor subunit 2(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM430523(US10556914, Example 3)
Affinity DataEC50: >1.00E+4nMAssay Description:The composition of the assay mixtures [in a final volume of 200 μL in 96-well U-bottom plates (Greiner) was as follows: 50 mM Tris-HCl buffer, p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGamma-aminobutyric acid type B receptor subunit 2(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM430524(US10556914, Example 4)
Affinity DataEC50:  1.66E+3nMAssay Description:The composition of the assay mixtures [in a final volume of 200 μL in 96-well U-bottom plates (Greiner) was as follows: 50 mM Tris-HCl buffer, p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGamma-aminobutyric acid type B receptor subunit 2(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM430525(US10556914, Example 6)
Affinity DataEC50:  1.96E+3nMAssay Description:The composition of the assay mixtures [in a final volume of 200 μL in 96-well U-bottom plates (Greiner) was as follows: 50 mM Tris-HCl buffer, p...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGamma-aminobutyric acid type B receptor subunit 2(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM430526(US10556914, Example 7)
Affinity DataEC50:  600nMAssay Description:The composition of the assay mixtures [in a final volume of 200 μL in 96-well U-bottom plates (Greiner) was as follows: 50 mM Tris-HCl buffer, p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGamma-aminobutyric acid type B receptor subunit 2(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM430527(US10556914, Example 8)
Affinity DataEC50:  2.11E+3nMAssay Description:The composition of the assay mixtures [in a final volume of 200 μL in 96-well U-bottom plates (Greiner) was as follows: 50 mM Tris-HCl buffer, p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGamma-aminobutyric acid type B receptor subunit 2(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM430528(US10556914, Example 10)
Affinity DataEC50:  1.06E+3nMAssay Description:The composition of the assay mixtures [in a final volume of 200 μL in 96-well U-bottom plates (Greiner) was as follows: 50 mM Tris-HCl buffer, p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGamma-aminobutyric acid type B receptor subunit 2(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM430530(US10556914, Example 11)
Affinity DataEC50: >1.00E+4nMAssay Description:The composition of the assay mixtures [in a final volume of 200 μL in 96-well U-bottom plates (Greiner) was as follows: 50 mM Tris-HCl buffer, p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGamma-aminobutyric acid type B receptor subunit 2(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM430531(US10556914, Example 12)
Affinity DataEC50:  347nMAssay Description:The composition of the assay mixtures [in a final volume of 200 μL in 96-well U-bottom plates (Greiner) was as follows: 50 mM Tris-HCl buffer, p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGamma-aminobutyric acid type B receptor subunit 2(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM430532(US10556914, Example 13)
Affinity DataEC50:  3.54E+3nMAssay Description:The composition of the assay mixtures [in a final volume of 200 μL in 96-well U-bottom plates (Greiner) was as follows: 50 mM Tris-HCl buffer, p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGamma-aminobutyric acid type B receptor subunit 2(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM430533(US10556914, Example 14)
Affinity DataEC50:  2.13E+3nMAssay Description:The composition of the assay mixtures [in a final volume of 200 μL in 96-well U-bottom plates (Greiner) was as follows: 50 mM Tris-HCl buffer, p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGamma-aminobutyric acid type B receptor subunit 2(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM430534(US10556914, Example 16)
Affinity DataEC50:  222nMAssay Description:The composition of the assay mixtures [in a final volume of 200 μL in 96-well U-bottom plates (Greiner) was as follows: 50 mM Tris-HCl buffer, p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGamma-aminobutyric acid type B receptor subunit 2(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM430535(US10556914, Example 18)
Affinity DataEC50:  389nMAssay Description:The composition of the assay mixtures [in a final volume of 200 μL in 96-well U-bottom plates (Greiner) was as follows: 50 mM Tris-HCl buffer, p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGamma-aminobutyric acid type B receptor subunit 2(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM430536(US10556914, Example 19)
Affinity DataEC50:  1.58E+3nMAssay Description:The composition of the assay mixtures [in a final volume of 200 μL in 96-well U-bottom plates (Greiner) was as follows: 50 mM Tris-HCl buffer, p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGamma-aminobutyric acid type B receptor subunit 2(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM430538(US10556914, Example 21)
Affinity DataEC50:  229nMAssay Description:The composition of the assay mixtures [in a final volume of 200 μL in 96-well U-bottom plates (Greiner) was as follows: 50 mM Tris-HCl buffer, p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGamma-aminobutyric acid type B receptor subunit 2(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM430539(US10556914, Example 22)
Affinity DataEC50:  2.69E+3nMAssay Description:The composition of the assay mixtures [in a final volume of 200 μL in 96-well U-bottom plates (Greiner) was as follows: 50 mM Tris-HCl buffer, p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGamma-aminobutyric acid type B receptor subunit 2(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM430540(US10556914, Example 23)
Affinity DataEC50: >1.00E+4nMAssay Description:The composition of the assay mixtures [in a final volume of 200 μL in 96-well U-bottom plates (Greiner) was as follows: 50 mM Tris-HCl buffer, p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGamma-aminobutyric acid type B receptor subunit 2(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM430541(US10556914, Example 24)
Affinity DataEC50:  1.85E+3nMAssay Description:The composition of the assay mixtures [in a final volume of 200 μL in 96-well U-bottom plates (Greiner) was as follows: 50 mM Tris-HCl buffer, p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGamma-aminobutyric acid type B receptor subunit 2(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM430542(US10556914, Example 27)
Affinity DataEC50:  3.20E+3nMAssay Description:The composition of the assay mixtures [in a final volume of 200 μL in 96-well U-bottom plates (Greiner) was as follows: 50 mM Tris-HCl buffer, p...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGamma-aminobutyric acid type B receptor subunit 2(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM430543(US10556914, Example 28)
Affinity DataEC50:  3.47E+3nMAssay Description:The composition of the assay mixtures [in a final volume of 200 μL in 96-well U-bottom plates (Greiner) was as follows: 50 mM Tris-HCl buffer, p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGamma-aminobutyric acid type B receptor subunit 2(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM430544(US10556914, Example 31)
Affinity DataEC50:  1.81E+3nMAssay Description:The composition of the assay mixtures [in a final volume of 200 μL in 96-well U-bottom plates (Greiner) was as follows: 50 mM Tris-HCl buffer, p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGamma-aminobutyric acid type B receptor subunit 2(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM430545(US10556914, Example 33)
Affinity DataEC50: >1.00E+4nMAssay Description:The composition of the assay mixtures [in a final volume of 200 μL in 96-well U-bottom plates (Greiner) was as follows: 50 mM Tris-HCl buffer, p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGamma-aminobutyric acid type B receptor subunit 2(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM430546(US10556914, Example 34)
Affinity DataEC50:  4.81E+3nMAssay Description:The composition of the assay mixtures [in a final volume of 200 μL in 96-well U-bottom plates (Greiner) was as follows: 50 mM Tris-HCl buffer, p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGamma-aminobutyric acid type B receptor subunit 2(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM430547(US10556914, Example 35)
Affinity DataEC50:  562nMAssay Description:The composition of the assay mixtures [in a final volume of 200 μL in 96-well U-bottom plates (Greiner) was as follows: 50 mM Tris-HCl buffer, p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGamma-aminobutyric acid type B receptor subunit 2(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM430548(US10556914, Example 36)
Affinity DataEC50:  895nMAssay Description:The composition of the assay mixtures [in a final volume of 200 μL in 96-well U-bottom plates (Greiner) was as follows: 50 mM Tris-HCl buffer, p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGamma-aminobutyric acid type B receptor subunit 2(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM430549(US10556914, Example 37)
Affinity DataEC50:  3.67E+3nMAssay Description:The composition of the assay mixtures [in a final volume of 200 μL in 96-well U-bottom plates (Greiner) was as follows: 50 mM Tris-HCl buffer, p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGamma-aminobutyric acid type B receptor subunit 2(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM430550(US10556914, Example 38)
Affinity DataEC50:  643nMAssay Description:The composition of the assay mixtures [in a final volume of 200 μL in 96-well U-bottom plates (Greiner) was as follows: 50 mM Tris-HCl buffer, p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGamma-aminobutyric acid type B receptor subunit 2(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM430551(US10556914, Example 39)
Affinity DataEC50:  105nMAssay Description:The composition of the assay mixtures [in a final volume of 200 μL in 96-well U-bottom plates (Greiner) was as follows: 50 mM Tris-HCl buffer, p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGamma-aminobutyric acid type B receptor subunit 2(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM430552(US10556914, Example 40)
Affinity DataEC50: >1.00E+4nMAssay Description:The composition of the assay mixtures [in a final volume of 200 μL in 96-well U-bottom plates (Greiner) was as follows: 50 mM Tris-HCl buffer, p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGamma-aminobutyric acid type B receptor subunit 2(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM430553(US10556914, Example 41)
Affinity DataEC50:  4.67E+3nMAssay Description:The composition of the assay mixtures [in a final volume of 200 μL in 96-well U-bottom plates (Greiner) was as follows: 50 mM Tris-HCl buffer, p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGamma-aminobutyric acid type B receptor subunit 2(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM430554(US10556914, Example 42)
Affinity DataEC50:  9.64E+3nMAssay Description:The composition of the assay mixtures [in a final volume of 200 μL in 96-well U-bottom plates (Greiner) was as follows: 50 mM Tris-HCl buffer, p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGamma-aminobutyric acid type B receptor subunit 2(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM430555(US10556914, Example 45)
Affinity DataEC50:  376nMAssay Description:The composition of the assay mixtures [in a final volume of 200 μL in 96-well U-bottom plates (Greiner) was as follows: 50 mM Tris-HCl buffer, p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGamma-aminobutyric acid type B receptor subunit 2(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM430556(US10556914, Example 46)
Affinity DataEC50:  2.29E+3nMAssay Description:The composition of the assay mixtures [in a final volume of 200 μL in 96-well U-bottom plates (Greiner) was as follows: 50 mM Tris-HCl buffer, p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGamma-aminobutyric acid type B receptor subunit 2(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM430557(US10556914, Example 47)
Affinity DataEC50:  578nMAssay Description:The composition of the assay mixtures [in a final volume of 200 μL in 96-well U-bottom plates (Greiner) was as follows: 50 mM Tris-HCl buffer, p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGamma-aminobutyric acid type B receptor subunit 2(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM430558(US10556914, Example 48)
Affinity DataEC50:  1.55E+3nMAssay Description:The composition of the assay mixtures [in a final volume of 200 μL in 96-well U-bottom plates (Greiner) was as follows: 50 mM Tris-HCl buffer, p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGamma-aminobutyric acid type B receptor subunit 2(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM430559(US10556914, Example 49)
Affinity DataEC50:  283nMAssay Description:The composition of the assay mixtures [in a final volume of 200 μL in 96-well U-bottom plates (Greiner) was as follows: 50 mM Tris-HCl buffer, p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGamma-aminobutyric acid type B receptor subunit 2(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM430560(US10556914, Example 51)
Affinity DataEC50:  1.50E+3nMAssay Description:The composition of the assay mixtures [in a final volume of 200 μL in 96-well U-bottom plates (Greiner) was as follows: 50 mM Tris-HCl buffer, p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGamma-aminobutyric acid type B receptor subunit 2(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM430561(US10556914, Example 52)
Affinity DataEC50: >1.00E+4nMAssay Description:The composition of the assay mixtures [in a final volume of 200 μL in 96-well U-bottom plates (Greiner) was as follows: 50 mM Tris-HCl buffer, p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGamma-aminobutyric acid type B receptor subunit 2(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM430562(US10556914, Example 53)
Affinity DataEC50:  620nMAssay Description:The composition of the assay mixtures [in a final volume of 200 μL in 96-well U-bottom plates (Greiner) was as follows: 50 mM Tris-HCl buffer, p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGamma-aminobutyric acid type B receptor subunit 2(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM430563(US10556914, Example 54)
Affinity DataEC50:  1.20E+3nMAssay Description:The composition of the assay mixtures [in a final volume of 200 μL in 96-well U-bottom plates (Greiner) was as follows: 50 mM Tris-HCl buffer, p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGamma-aminobutyric acid type B receptor subunit 2(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM430564(US10556914, Example 55)
Affinity DataEC50:  80nMAssay Description:The composition of the assay mixtures [in a final volume of 200 μL in 96-well U-bottom plates (Greiner) was as follows: 50 mM Tris-HCl buffer, p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGamma-aminobutyric acid type B receptor subunit 2(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM430565(US10556914, Example 56)
Affinity DataEC50:  982nMAssay Description:The composition of the assay mixtures [in a final volume of 200 μL in 96-well U-bottom plates (Greiner) was as follows: 50 mM Tris-HCl buffer, p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGamma-aminobutyric acid type B receptor subunit 2(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM430566(US10556914, Example 57)
Affinity DataEC50:  3.33E+3nMAssay Description:The composition of the assay mixtures [in a final volume of 200 μL in 96-well U-bottom plates (Greiner) was as follows: 50 mM Tris-HCl buffer, p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGamma-aminobutyric acid type B receptor subunit 2(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM430567(US10556914, Example 58)
Affinity DataEC50: >1.00E+4nMAssay Description:The composition of the assay mixtures [in a final volume of 200 μL in 96-well U-bottom plates (Greiner) was as follows: 50 mM Tris-HCl buffer, p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGamma-aminobutyric acid type B receptor subunit 2(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM430568(US10556914, Example 59)
Affinity DataEC50:  17nMAssay Description:The composition of the assay mixtures [in a final volume of 200 μL in 96-well U-bottom plates (Greiner) was as follows: 50 mM Tris-HCl buffer, p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGamma-aminobutyric acid type B receptor subunit 2(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM430569(US10556914, Example 60)
Affinity DataEC50: >1.00E+4nMAssay Description:The composition of the assay mixtures [in a final volume of 200 μL in 96-well U-bottom plates (Greiner) was as follows: 50 mM Tris-HCl buffer, p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGamma-aminobutyric acid type B receptor subunit 2(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM430570(US10556914, Example 61)
Affinity DataEC50: >1.00E+4nMAssay Description:The composition of the assay mixtures [in a final volume of 200 μL in 96-well U-bottom plates (Greiner) was as follows: 50 mM Tris-HCl buffer, p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGamma-aminobutyric acid type B receptor subunit 2(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM430571(US10556914, Example 63)
Affinity DataEC50:  491nMAssay Description:The composition of the assay mixtures [in a final volume of 200 μL in 96-well U-bottom plates (Greiner) was as follows: 50 mM Tris-HCl buffer, p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGamma-aminobutyric acid type B receptor subunit 2(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM430572(N-(4-methoxy-3-{3-methyl-4-oxo-5-[4-(trifluorometh...)
Affinity DataEC50:  644nMAssay Description:The composition of the assay mixtures [in a final volume of 200 μL in 96-well U-bottom plates (Greiner) was as follows: 50 mM Tris-HCl buffer, p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
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