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Found 27 Enz. Inhib. hit(s) with all data for entry = 8968
TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens (Human))
Synblia Therapeutics

US Patent
LigandPNGBDBM433290(3-(4-(aminomethyl)-4- methylpiperidin-1-yl)-6- ((2...)
Affinity DataIC50: <50nMAssay Description:IC50 values were determined at room temperature in 384-well black polystyrene plate, using a final reaction volume of 15 μl and the following as...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens (Human))
Synblia Therapeutics

US Patent
LigandPNGBDBM433315((S)-3-(1-amino-1,3- dihydrospiro[indene-2,4'- pipe...)
Affinity DataIC50: <50nMAssay Description:IC50 values were determined at room temperature in 384-well black polystyrene plate, using a final reaction volume of 15 μl and the following as...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens (Human))
Synblia Therapeutics

US Patent
LigandPNGBDBM433298(N-(3-((5-(4- (aminomethyl)-4- methylpiperidin-1-yl...)
Affinity DataIC50: <50nMAssay Description:IC50 values were determined at room temperature in 384-well black polystyrene plate, using a final reaction volume of 15 μl and the following as...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens (Human))
Synblia Therapeutics

US Patent
LigandPNGBDBM433312(3-((3S,4S)-4-amino-3- methyl-2-oxa-8- azaspiro[4.5...)
Affinity DataIC50: <50nMAssay Description:IC50 values were determined at room temperature in 384-well black polystyrene plate, using a final reaction volume of 15 μl and the following as...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens (Human))
Synblia Therapeutics

US Patent
LigandPNGBDBM433313(3-(2- aminospiro[bicyclo[3.1.0] hexane-3,4'-piperi...)
Affinity DataIC50: <50nMAssay Description:IC50 values were determined at room temperature in 384-well black polystyrene plate, using a final reaction volume of 15 μl and the following as...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens (Human))
Synblia Therapeutics

US Patent
LigandPNGBDBM433291(6-(4-(aminomethyl)-4- methylpiperidin-1-yl)-3- (2,...)
Affinity DataIC50: <50nMAssay Description:IC50 values were determined at room temperature in 384-well black polystyrene plate, using a final reaction volume of 15 μl and the following as...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens (Human))
Synblia Therapeutics

US Patent
LigandPNGBDBM433293(6-(4-(aminomethyl)-4- methylpiperidin-1-yl)-3- ((2...)
Affinity DataIC50: <50nMAssay Description:IC50 values were determined at room temperature in 384-well black polystyrene plate, using a final reaction volume of 15 μl and the following as...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens (Human))
Synblia Therapeutics

US Patent
LigandPNGBDBM433294(6-((2-amino-3- chloropyridin-4-yl)thio)-3- ((3S,4S...)
Affinity DataIC50: <50nMAssay Description:IC50 values were determined at room temperature in 384-well black polystyrene plate, using a final reaction volume of 15 μl and the following as...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens (Human))
Synblia Therapeutics

US Patent
LigandPNGBDBM433295(N-(3-((5-(4- (aminomethyl)-4- methylpiperidin-1-yl...)
Affinity DataIC50: <50nMAssay Description:IC50 values were determined at room temperature in 384-well black polystyrene plate, using a final reaction volume of 15 μl and the following as...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens (Human))
Synblia Therapeutics

US Patent
LigandPNGBDBM433296(N-(3-((5-(4- (aminomethyl)-4- methylpiperidin-1-yl...)
Affinity DataIC50: <50nMAssay Description:IC50 values were determined at room temperature in 384-well black polystyrene plate, using a final reaction volume of 15 μl and the following as...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens (Human))
Synblia Therapeutics

US Patent
LigandPNGBDBM433297(N-(3-((5-(4- (aminomethyl)-4- methylpiperidin-1-yl...)
Affinity DataIC50: <50nMAssay Description:IC50 values were determined at room temperature in 384-well black polystyrene plate, using a final reaction volume of 15 μl and the following as...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens (Human))
Synblia Therapeutics

US Patent
LigandPNGBDBM433300(N-(3-((5-(4- (aminomethyl)-4- methylpiperidin-1-yl...)
Affinity DataIC50: <50nMAssay Description:IC50 values were determined at room temperature in 384-well black polystyrene plate, using a final reaction volume of 15 μl and the following as...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens (Human))
Synblia Therapeutics

US Patent
LigandPNGBDBM433301(3-((3S,4S)-4-amino-3- methyl-2-oxa-8- azaspiro[4.5...)
Affinity DataIC50: <50nMAssay Description:IC50 values were determined at room temperature in 384-well black polystyrene plate, using a final reaction volume of 15 μl and the following as...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens (Human))
Synblia Therapeutics

US Patent
LigandPNGBDBM433302((S)-3-(4-amino-2-oxa-8- azaspiro[4.5]decan-8-yl)- ...)
Affinity DataIC50: <50nMAssay Description:IC50 values were determined at room temperature in 384-well black polystyrene plate, using a final reaction volume of 15 μl and the following as...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens (Human))
Synblia Therapeutics

US Patent
LigandPNGBDBM433303(1-(3-aminocyclohexyl)-4- (2,3- dichlorophenyl)pyri...)
Affinity DataIC50: <50nMAssay Description:IC50 values were determined at room temperature in 384-well black polystyrene plate, using a final reaction volume of 15 μl and the following as...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens (Human))
Synblia Therapeutics

US Patent
LigandPNGBDBM433304(N-(3-((5-(4- (aminomethyl)-4- methylpiperidin-1-yl...)
Affinity DataIC50: <50nMAssay Description:IC50 values were determined at room temperature in 384-well black polystyrene plate, using a final reaction volume of 15 μl and the following as...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens (Human))
Synblia Therapeutics

US Patent
LigandPNGBDBM433305(3-((3S,4S)-4-amino-3- methyl-2-oxa-8- azaspiro[4.5...)
Affinity DataIC50: <50nMAssay Description:IC50 values were determined at room temperature in 384-well black polystyrene plate, using a final reaction volume of 15 μl and the following as...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens (Human))
Synblia Therapeutics

US Patent
LigandPNGBDBM433306(3-((3S,4S)-4-amino-3- methyl-2-oxa-8- azaspiro[4.5...)
Affinity DataIC50: <50nMAssay Description:IC50 values were determined at room temperature in 384-well black polystyrene plate, using a final reaction volume of 15 μl and the following as...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens (Human))
Synblia Therapeutics

US Patent
LigandPNGBDBM433307(3-((3S,4S)-4-amino-3- methyl-2-oxa-8- azaspiro[4.5...)
Affinity DataIC50: <50nMAssay Description:IC50 values were determined at room temperature in 384-well black polystyrene plate, using a final reaction volume of 15 μl and the following as...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens (Human))
Synblia Therapeutics

US Patent
LigandPNGBDBM433308(4-((5-(4-(aminomethyl)-4- methylpiperidin-1-yl)-6-...)
Affinity DataIC50: <50nMAssay Description:IC50 values were determined at room temperature in 384-well black polystyrene plate, using a final reaction volume of 15 μl and the following as...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens (Human))
Synblia Therapeutics

US Patent
LigandPNGBDBM433309(3-((3S,4S)-4-amino-3- methyl-2-oxa-8- azaspiro[4.5...)
Affinity DataIC50: <50nMAssay Description:IC50 values were determined at room temperature in 384-well black polystyrene plate, using a final reaction volume of 15 μl and the following as...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens (Human))
Synblia Therapeutics

US Patent
LigandPNGBDBM433310(3-((3S,4S)-4-amino-3- methyl-2-oxa-8- azaspiro[4.5...)
Affinity DataIC50: <50nMAssay Description:IC50 values were determined at room temperature in 384-well black polystyrene plate, using a final reaction volume of 15 μl and the following as...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens (Human))
Synblia Therapeutics

US Patent
LigandPNGBDBM433311(3-((3S,4S)-4-amino-3- methyl-2-oxa-8- azaspiro[4.5...)
Affinity DataIC50: <50nMAssay Description:IC50 values were determined at room temperature in 384-well black polystyrene plate, using a final reaction volume of 15 μl and the following as...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens (Human))
Synblia Therapeutics

US Patent
LigandPNGBDBM433314(3-(6-amino-3- azabicyclo[3.1.0]hexan-3- yl)-6-((2,...)
Affinity DataIC50: <50nMAssay Description:IC50 values were determined at room temperature in 384-well black polystyrene plate, using a final reaction volume of 15 μl and the following as...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens (Human))
Synblia Therapeutics

US Patent
LigandPNGBDBM433316((R)-3-(3-amino-3H- spiro[benzofuran-2,4'- piperidi...)
Affinity DataIC50: <50nMAssay Description:IC50 values were determined at room temperature in 384-well black polystyrene plate, using a final reaction volume of 15 μl and the following as...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens (Human))
Synblia Therapeutics

US Patent
LigandPNGBDBM433317((S)-3-(4-amino-2-oxa-8- azaspiro[4.5]decan-8-yl)- ...)
Affinity DataIC50: <50nMAssay Description:IC50 values were determined at room temperature in 384-well black polystyrene plate, using a final reaction volume of 15 μl and the following as...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens (Human))
Synblia Therapeutics

US Patent
LigandPNGBDBM433292(6-amino-2-(3- (aminomethyl)-3- methylpyrrolidin-1-...)
Affinity DataIC50: <50nMAssay Description:IC50 values were determined at room temperature in 384-well black polystyrene plate, using a final reaction volume of 15 μl and the following as...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent