Compile Data Set for Download or QSAR
maximum 50k data
Found 16 Enz. Inhib. hit(s) with all data for entry = 9222
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM450373(1-{2,6-dichloro-4-[(2R)-1,1,1-trifluoro-2-hydroxy-...)
Affinity DataIC50: >1.00E+4nMAssay Description:Using HEK293 cell overexpressing a human ether-a-go-go-related gene (hERG), the maximum tale current of the hERG IKr current induced by redepolarizat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM450382(1-[4-(1-amino-2,2,2-trifluoroethyl)-2,6-dichloroph...)
Affinity DataIC50: >1.00E+4nMAssay Description:Using HEK293 cell overexpressing a human ether-a-go-go-related gene (hERG), the maximum tale current of the hERG IKr current induced by redepolarizat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM450373(1-{2,6-dichloro-4-[(2R)-1,1,1-trifluoro-2-hydroxy-...)
Affinity DataIC50: >1.00E+4nMAssay Description:Using HEK293 cell overexpressing a human ether-a-go-go-related gene (hERG), the maximum tale current of the hERG IKr current induced by redepolarizat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM450373(1-{2,6-dichloro-4-[(2R)-1,1,1-trifluoro-2-hydroxy-...)
Affinity DataIC50: >1.00E+4nMAssay Description:Using HEK293 cell overexpressing a human ether-a-go-go-related gene (hERG), the maximum tale current of the hERG IKr current induced by redepolarizat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM450374(1-{2,6-dichloro-4-[(2R)-1,1,1-trifluoro-2-hydroxy-...)
Affinity DataIC50: >1.00E+4nMAssay Description:Using HEK293 cell overexpressing a human ether-a-go-go-related gene (hERG), the maximum tale current of the hERG IKr current induced by redepolarizat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM450375(1-{2,6-dichloro-4-[(2S)-1,1,1-trifluoro-2-hydroxy-...)
Affinity DataIC50: >1.00E+4nMAssay Description:Using HEK293 cell overexpressing a human ether-a-go-go-related gene (hERG), the maximum tale current of the hERG IKr current induced by redepolarizat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM450375(1-{2,6-dichloro-4-[(2S)-1,1,1-trifluoro-2-hydroxy-...)
Affinity DataIC50: >1.00E+4nMAssay Description:Using HEK293 cell overexpressing a human ether-a-go-go-related gene (hERG), the maximum tale current of the hERG IKr current induced by redepolarizat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM450375(1-{2,6-dichloro-4-[(2S)-1,1,1-trifluoro-2-hydroxy-...)
Affinity DataIC50: >1.00E+4nMAssay Description:Using HEK293 cell overexpressing a human ether-a-go-go-related gene (hERG), the maximum tale current of the hERG IKr current induced by redepolarizat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM450376(1-{2,6-dichloro-4-[(2S)-1,1,1-trifluoro-2-hydroxy-...)
Affinity DataIC50: >1.00E+4nMAssay Description:Using HEK293 cell overexpressing a human ether-a-go-go-related gene (hERG), the maximum tale current of the hERG IKr current induced by redepolarizat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM450377(1-{2,6-dichloro-4-[(1R)-2,2,2-trifluoro-1-hydroxye...)
Affinity DataIC50: >1.00E+4nMAssay Description:Using HEK293 cell overexpressing a human ether-a-go-go-related gene (hERG), the maximum tale current of the hERG IKr current induced by redepolarizat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM450377(1-{2,6-dichloro-4-[(1R)-2,2,2-trifluoro-1-hydroxye...)
Affinity DataIC50: >1.00E+4nMAssay Description:Using HEK293 cell overexpressing a human ether-a-go-go-related gene (hERG), the maximum tale current of the hERG IKr current induced by redepolarizat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM450378(1-{2,6-dichloro-4-[(1R)-2,2,2-trifluoro-1-hydroxye...)
Affinity DataIC50: >1.00E+4nMAssay Description:Using HEK293 cell overexpressing a human ether-a-go-go-related gene (hERG), the maximum tale current of the hERG IKr current induced by redepolarizat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM450379(1-{2,6-dichloro-4-[(1S)-2,2,2-trifluoro-1-hydroxye...)
Affinity DataIC50: >1.00E+4nMAssay Description:Using HEK293 cell overexpressing a human ether-a-go-go-related gene (hERG), the maximum tale current of the hERG IKr current induced by redepolarizat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM450380(1-{2,6-dichloro-4-[(1S)-2,2,2-trifluoro-1-hydroxye...)
Affinity DataIC50: >1.00E+4nMAssay Description:Using HEK293 cell overexpressing a human ether-a-go-go-related gene (hERG), the maximum tale current of the hERG IKr current induced by redepolarizat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM450381(2-cyclohexyl-N-[2,6-dichloro-4-(1,1,1-trifluoro-2-...)
Affinity DataIC50: >1.00E+4nMAssay Description:Using HEK293 cell overexpressing a human ether-a-go-go-related gene (hERG), the maximum tale current of the hERG IKr current induced by redepolarizat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM450373(1-{2,6-dichloro-4-[(2R)-1,1,1-trifluoro-2-hydroxy-...)
Affinity DataIC50: >1.00E+4nMAssay Description:Using HEK293 cell overexpressing a human ether-a-go-go-related gene (hERG), the maximum tale current of the hERG IKr current induced by redepolarizat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent