Compile Data Set for Download or QSAR
maximum 50k data
Found 34 Enz. Inhib. hit(s) with all data for entry = 9285
TargetRibosomal protein S6 kinase beta-1(Homo sapiens (Human))
Sentinel Oncology

US Patent
LigandPNGBDBM455397((R)-3-Phenyl-3-[6-(1H- | US10730882, Example 31)
Affinity DataIC50:  10nMAssay Description:In a final reaction volume of 25 μL, p70S6K (h) (5-10 mU) is incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 100 μM KKRNRTLTV, 10 mM Mg aceta...More data for this Ligand-Target Pair
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In DepthDetails US Patent
TargetRibosomal protein S6 kinase beta-1(Homo sapiens (Human))
Sentinel Oncology

US Patent
LigandPNGBDBM455385(US10730882, Example 19 | [(R)-1-(3,4-Difluoro-)
Affinity DataIC50:  10nMAssay Description:In a final reaction volume of 25 μL, p70S6K (h) (5-10 mU) is incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 100 μM KKRNRTLTV, 10 mM Mg aceta...More data for this Ligand-Target Pair
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In DepthDetails US Patent
TargetRibosomal protein S6 kinase beta-1(Homo sapiens (Human))
Sentinel Oncology

US Patent
LigandPNGBDBM455365(((R)-1-Phenyl-ethyl)-[6-(1H-pyrazolo[3,4-d]pyrimid...)
Affinity DataIC50:  13nMAssay Description:In a final reaction volume of 25 μL, p70S6K (h) (5-10 mU) is incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 100 μM KKRNRTLTV, 10 mM Mg aceta...More data for this Ligand-Target Pair
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TargetRibosomal protein S6 kinase beta-1(Homo sapiens (Human))
Sentinel Oncology

US Patent
LigandPNGBDBM455394(US10730882, Example 28 | [(R)-1-(2-Fluoro-phenyl)-)
Affinity DataIC50:  15nMAssay Description:In a final reaction volume of 25 μL, p70S6K (h) (5-10 mU) is incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 100 μM KKRNRTLTV, 10 mM Mg aceta...More data for this Ligand-Target Pair
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In DepthDetails US Patent
TargetRibosomal protein S6 kinase beta-1(Homo sapiens (Human))
Sentinel Oncology

US Patent
LigandPNGBDBM455375((3-Fluorobenzyl)-[6-(1H- | US10730882, Example 10)
Affinity DataIC50:  18nMAssay Description:In a final reaction volume of 25 μL, p70S6K (h) (5-10 mU) is incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 100 μM KKRNRTLTV, 10 mM Mg aceta...More data for this Ligand-Target Pair
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In DepthDetails US Patent
TargetRibosomal protein S6 kinase beta-1(Homo sapiens (Human))
Sentinel Oncology

US Patent
LigandPNGBDBM455400(2-{(R)-1-[6-(1H- | US10730882, Example 35)
Affinity DataIC50:  20nMAssay Description:In a final reaction volume of 25 μL, p70S6K (h) (5-10 mU) is incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 100 μM KKRNRTLTV, 10 mM Mg aceta...More data for this Ligand-Target Pair
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TargetRibosomal protein S6 kinase beta-1(Homo sapiens (Human))
Sentinel Oncology

US Patent
LigandPNGBDBM455367(((R)-1-(3-Fluoro-phenyl)- | US10730882, Example 3)
Affinity DataIC50:  21nMAssay Description:In a final reaction volume of 25 μL, p70S6K (h) (5-10 mU) is incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 100 μM KKRNRTLTV, 10 mM Mg aceta...More data for this Ligand-Target Pair
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In DepthDetails US Patent
TargetRibosomal protein S6 kinase beta-1(Homo sapiens (Human))
Sentinel Oncology

US Patent
LigandPNGBDBM455368(((R)-1-(4-Fluoro-phenyl)- | US10730882, Example 4)
Affinity DataIC50:  22nMAssay Description:In a final reaction volume of 25 μL, p70S6K (h) (5-10 mU) is incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 100 μM KKRNRTLTV, 10 mM Mg aceta...More data for this Ligand-Target Pair
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TargetRibosomal protein S6 kinase beta-1(Homo sapiens (Human))
Sentinel Oncology

US Patent
LigandPNGBDBM455396(N-(3-{(R)-1-[6-(1H- | US10730882, Example 30)
Affinity DataIC50:  23nMAssay Description:In a final reaction volume of 25 μL, p70S6K (h) (5-10 mU) is incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 100 μM KKRNRTLTV, 10 mM Mg aceta...More data for this Ligand-Target Pair
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TargetRibosomal protein S6 kinase beta-1(Homo sapiens (Human))
Sentinel Oncology

US Patent
LigandPNGBDBM455369(((S)-2-Hydroxy-1-phenyl- | US10730882, Example 5)
Affinity DataIC50:  24nMAssay Description:In a final reaction volume of 25 μL, p70S6K (h) (5-10 mU) is incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 100 μM KKRNRTLTV, 10 mM Mg aceta...More data for this Ligand-Target Pair
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TargetRibosomal protein S6 kinase beta-1(Homo sapiens (Human))
Sentinel Oncology

US Patent
LigandPNGBDBM455384(Benzyl-(S)-1-morpholin- | US10730882, Example 18)
Affinity DataIC50:  25nMAssay Description:In a final reaction volume of 25 μL, p70S6K (h) (5-10 mU) is incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 100 μM KKRNRTLTV, 10 mM Mg aceta...More data for this Ligand-Target Pair
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In DepthDetails US Patent
TargetRibosomal protein S6 kinase beta-1(Homo sapiens (Human))
Sentinel Oncology

US Patent
LigandPNGBDBM455398(US10730882, Example 33 | [(R)-1-(2,6-Difluoro-)
Affinity DataIC50:  28nMAssay Description:In a final reaction volume of 25 μL, p70S6K (h) (5-10 mU) is incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 100 μM KKRNRTLTV, 10 mM Mg aceta...More data for this Ligand-Target Pair
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TargetRibosomal protein S6 kinase beta-1(Homo sapiens (Human))
Sentinel Oncology

US Patent
LigandPNGBDBM455366(((R)-1-(3-Chloro-phenyl)- | US10730882, Example 2)
Affinity DataIC50:  30nMAssay Description:In a final reaction volume of 25 μL, p70S6K (h) (5-10 mU) is incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 100 μM KKRNRTLTV, 10 mM Mg aceta...More data for this Ligand-Target Pair
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TargetRibosomal protein S6 kinase beta-1(Homo sapiens (Human))
Sentinel Oncology

US Patent
LigandPNGBDBM455372(Benzyl-[6-(1H- | US10730882, Example 7)
Affinity DataIC50:  33nMAssay Description:In a final reaction volume of 25 μL, p70S6K (h) (5-10 mU) is incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 100 μM KKRNRTLTV, 10 mM Mg aceta...More data for this Ligand-Target Pair
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In DepthDetails US Patent
TargetRibosomal protein S6 kinase beta-1(Homo sapiens (Human))
Sentinel Oncology

US Patent
LigandPNGBDBM455393(US10730882, Example 27 | [(R)-1-(3-Methoxy-)
Affinity DataIC50:  41nMAssay Description:In a final reaction volume of 25 μL, p70S6K (h) (5-10 mU) is incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 100 μM KKRNRTLTV, 10 mM Mg aceta...More data for this Ligand-Target Pair
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TargetRibosomal protein S6 kinase beta-1(Homo sapiens (Human))
Sentinel Oncology

US Patent
LigandPNGBDBM455378(((R)-1-Phenyl-ethyl)-[6- | US10730882, Example 13)
Affinity DataIC50:  43nMAssay Description:In a final reaction volume of 25 μL, p70S6K (h) (5-10 mU) is incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 100 μM KKRNRTLTV, 10 mM Mg aceta...More data for this Ligand-Target Pair
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TargetRibosomal protein S6 kinase beta-1(Homo sapiens (Human))
Sentinel Oncology

US Patent
LigandPNGBDBM455391((3,4-Difluoro-benzyl)-[6- | US10730882, Example 25)
Affinity DataIC50:  49nMAssay Description:In a final reaction volume of 25 μL, p70S6K (h) (5-10 mU) is incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 100 μM KKRNRTLTV, 10 mM Mg aceta...More data for this Ligand-Target Pair
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TargetRibosomal protein S6 kinase beta-1(Homo sapiens (Human))
Sentinel Oncology

US Patent
LigandPNGBDBM455374((4-Fluorobenzyl)-[6-(1H- | US10730882, Example 9)
Affinity DataIC50:  55nMAssay Description:In a final reaction volume of 25 μL, p70S6K (h) (5-10 mU) is incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 100 μM KKRNRTLTV, 10 mM Mg aceta...More data for this Ligand-Target Pair
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TargetRibosomal protein S6 kinase beta-1(Homo sapiens (Human))
Sentinel Oncology

US Patent
LigandPNGBDBM455379(((R)-1-Phenyl-ethyl)-[6- | US10730882, Example 14)
Affinity DataIC50:  57nMAssay Description:In a final reaction volume of 25 μL, p70S6K (h) (5-10 mU) is incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 100 μM KKRNRTLTV, 10 mM Mg aceta...More data for this Ligand-Target Pair
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TargetRibosomal protein S6 kinase beta-1(Homo sapiens (Human))
Sentinel Oncology

US Patent
LigandPNGBDBM455392(N-(3-{[6-(1H- | US10730882, Example 26)
Affinity DataIC50:  67nMAssay Description:In a final reaction volume of 25 μL, p70S6K (h) (5-10 mU) is incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 100 μM KKRNRTLTV, 10 mM Mg aceta...More data for this Ligand-Target Pair
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TargetRibosomal protein S6 kinase beta-1(Homo sapiens (Human))
Sentinel Oncology

US Patent
LigandPNGBDBM455387(Benzyl-[6-(1H- | US10730882, Example 21)
Affinity DataIC50:  71nMAssay Description:In a final reaction volume of 25 μL, p70S6K (h) (5-10 mU) is incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 100 μM KKRNRTLTV, 10 mM Mg aceta...More data for this Ligand-Target Pair
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TargetRibosomal protein S6 kinase beta-1(Homo sapiens (Human))
Sentinel Oncology

US Patent
LigandPNGBDBM455380(((R)-1-Phenyl-ethyl)-[6- | US10730882, Example 15)
Affinity DataIC50:  97nMAssay Description:In a final reaction volume of 25 μL, p70S6K (h) (5-10 mU) is incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 100 μM KKRNRTLTV, 10 mM Mg aceta...More data for this Ligand-Target Pair
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TargetRibosomal protein S6 kinase beta-1(Homo sapiens (Human))
Sentinel Oncology

US Patent
LigandPNGBDBM455382(N-Benzyl-N',N'-dimethyl- | US10730882, Example 16)
Affinity DataIC50:  106nMAssay Description:In a final reaction volume of 25 μL, p70S6K (h) (5-10 mU) is incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 100 μM KKRNRTLTV, 10 mM Mg aceta...More data for this Ligand-Target Pair
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TargetRibosomal protein S6 kinase beta-1(Homo sapiens (Human))
Sentinel Oncology

US Patent
LigandPNGBDBM455373(((R)-1-Phenyl-ethyl)-[6- | US10730882, Example 8)
Affinity DataIC50:  108nMAssay Description:In a final reaction volume of 25 μL, p70S6K (h) (5-10 mU) is incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 100 μM KKRNRTLTV, 10 mM Mg aceta...More data for this Ligand-Target Pair
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TargetRibosomal protein S6 kinase beta-1(Homo sapiens (Human))
Sentinel Oncology

US Patent
LigandPNGBDBM455383(Benzyl-(R)-1-morpholin- | US10730882, Example 17)
Affinity DataIC50:  110nMAssay Description:In a final reaction volume of 25 μL, p70S6K (h) (5-10 mU) is incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 100 μM KKRNRTLTV, 10 mM Mg aceta...More data for this Ligand-Target Pair
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TargetRibosomal protein S6 kinase beta-1(Homo sapiens (Human))
Sentinel Oncology

US Patent
LigandPNGBDBM455389((3-Methoxy-benzyl)-[6- | US10730882, Example 23)
Affinity DataIC50:  118nMAssay Description:In a final reaction volume of 25 μL, p70S6K (h) (5-10 mU) is incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 100 μM KKRNRTLTV, 10 mM Mg aceta...More data for this Ligand-Target Pair
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TargetRibosomal protein S6 kinase beta-1(Homo sapiens (Human))
Sentinel Oncology

US Patent
LigandPNGBDBM455388(US10730882, Example 22 | [6-(3-Methyl-1H-)
Affinity DataIC50:  131nMAssay Description:In a final reaction volume of 25 μL, p70S6K (h) (5-10 mU) is incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 100 μM KKRNRTLTV, 10 mM Mg aceta...More data for this Ligand-Target Pair
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TargetRibosomal protein S6 kinase beta-1(Homo sapiens (Human))
Sentinel Oncology

US Patent
LigandPNGBDBM455376((3-Chlorobenzyl)-[6-(1H- | US10730882, Example 11)
Affinity DataIC50:  145nMAssay Description:In a final reaction volume of 25 μL, p70S6K (h) (5-10 mU) is incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 100 μM KKRNRTLTV, 10 mM Mg aceta...More data for this Ligand-Target Pair
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TargetRibosomal protein S6 kinase beta-1(Homo sapiens (Human))
Sentinel Oncology

US Patent
LigandPNGBDBM455370((4-Fluorobenzyl)-[6-(1H- | US10730882, Example 6)
Affinity DataIC50:  147nMAssay Description:In a final reaction volume of 25 μL, p70S6K (h) (5-10 mU) is incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 100 μM KKRNRTLTV, 10 mM Mg aceta...More data for this Ligand-Target Pair
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TargetRibosomal protein S6 kinase beta-1(Homo sapiens (Human))
Sentinel Oncology

US Patent
LigandPNGBDBM455386(((R)-1-Phenyl-ethyl)-[6- | US10730882, Example 20)
Affinity DataIC50:  167nMAssay Description:In a final reaction volume of 25 μL, p70S6K (h) (5-10 mU) is incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 100 μM KKRNRTLTV, 10 mM Mg aceta...More data for this Ligand-Target Pair
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TargetRibosomal protein S6 kinase beta-1(Homo sapiens (Human))
Sentinel Oncology

US Patent
LigandPNGBDBM455390((2-Fluoro-benzyl)-[6-(1H- | US10730882, Example 24)
Affinity DataIC50:  204nMAssay Description:In a final reaction volume of 25 μL, p70S6K (h) (5-10 mU) is incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 100 μM KKRNRTLTV, 10 mM Mg aceta...More data for this Ligand-Target Pair
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TargetRibosomal protein S6 kinase beta-1(Homo sapiens (Human))
Sentinel Oncology

US Patent
LigandPNGBDBM455399(4-[2-((R)-1-Phenyl- | US10730882, Example 34)
Affinity DataIC50:  346nMAssay Description:In a final reaction volume of 25 μL, p70S6K (h) (5-10 mU) is incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 100 μM KKRNRTLTV, 10 mM Mg aceta...More data for this Ligand-Target Pair
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TargetRibosomal protein S6 kinase beta-1(Homo sapiens (Human))
Sentinel Oncology

US Patent
LigandPNGBDBM455395(((S)-1-Phenyl-ethyl)-[6- | US10730882, Example 29)
Affinity DataIC50: >3.00E+3nMAssay Description:In a final reaction volume of 25 μL, p70S6K (h) (5-10 mU) is incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 100 μM KKRNRTLTV, 10 mM Mg aceta...More data for this Ligand-Target Pair
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TargetRibosomal protein S6 kinase beta-1(Homo sapiens (Human))
Sentinel Oncology

US Patent
LigandPNGBDBM455377(((R)-1-Phenyl-ethyl)-[7- | US10730882, Example 12)
Affinity DataIC50: >3.00E+3nMAssay Description:In a final reaction volume of 25 μL, p70S6K (h) (5-10 mU) is incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 100 μM KKRNRTLTV, 10 mM Mg aceta...More data for this Ligand-Target Pair
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