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Patent code US10787419

Compile Data Set for Download or QSAR
Found 92 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Cannabinoid receptor 1


(Mus musculus (Mouse))
BDBM463872
PNG
(US10787419, Serial # 72)
Show SMILES CC(=O)NC(=N)C(=N/S(=O)(=O)c1ccc(cc1)C(F)(F)F)\N1CC(C(=N1)c1ccc(Cl)cc1)c1ccccc1
Show InChI InChI=1S/C26H21ClF3N5O3S/c1-16(36)32-24(31)25(34-39(37,38)21-13-9-19(10-14-21)26(28,29)30)35-15-22(17-5-3-2-4-6-17)23(33-35)18-7-11-20(27)12-8-18/h2-14,22H,15H2,1H3,(H2,31,32,36)/b34-25+
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2.70n/an/an/an/an/an/an/an/a



The United States of America, as represented by the Secretary, Department of Health and Human Services

US Patent


Assay Description
Measuring its tissue levels 1 hour after administration of 10 mg/kg to mice, plasma levels were comparable after oral or i.p. administration (indicat...


US Patent US10787419 (2020)

More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Mus musculus (Mouse))
BDBM463870
PNG
(US10787419, Serial # 70)
Show SMILES CC(=O)NC(=N)C(=N/S(=O)(=O)c1ccc(I)cc1)\N1CC(C(=N1)c1ccc(Cl)cc1)c1ccccc1
Show InChI InChI=1S/C25H21ClIN5O3S/c1-16(33)29-24(28)25(31-36(34,35)21-13-11-20(27)12-14-21)32-15-22(17-5-3-2-4-6-17)23(30-32)18-7-9-19(26)10-8-18/h2-14,22H,15H2,1H3,(H2,28,29,33)/b31-25+
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3.20n/an/an/an/an/an/an/an/a



The United States of America, as represented by the Secretary, Department of Health and Human Services

US Patent


Assay Description
Measuring its tissue levels 1 hour after administration of 10 mg/kg to mice, plasma levels were comparable after oral or i.p. administration (indicat...


US Patent US10787419 (2020)

More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Mus musculus (Mouse))
BDBM463781
PNG
(US10787419, Serial # 3E1)
Show SMILES CC(C)(C)C(=N)C(=N/S(=O)(=O)c1ccc(Cl)cc1)\N1C[C@@H](C(=N1)c1ccc(Cl)cc1)c1ccccc1
Show InChI InChI=1S/C27H26Cl2N4O2S/c1-27(2,3)25(30)26(32-36(34,35)22-15-13-21(29)14-16-22)33-17-23(18-7-5-4-6-8-18)24(31-33)19-9-11-20(28)12-10-19/h4-16,23,30H,17H2,1-3H3/b30-25?,32-26+/t23-/m1/s1
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3.60n/an/an/an/an/an/an/an/a



The United States of America, as represented by the Secretary, Department of Health and Human Services

US Patent


Assay Description
Measuring its tissue levels 1 hour after administration of 10 mg/kg to mice, plasma levels were comparable after oral or i.p. administration (indicat...


US Patent US10787419 (2020)

More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Mus musculus (Mouse))
BDBM463825
PNG
(US10787419, Serial # 34)
Show SMILES CC(=N)C(=N/S(=O)(=O)c1ccc(cc1)C(F)(F)F)\N1CC(C(=N1)c1ccc(Cl)cc1)c1ccccc1
Show InChI InChI=1S/C25H20ClF3N4O2S/c1-16(30)24(32-36(34,35)21-13-9-19(10-14-21)25(27,28)29)33-15-22(17-5-3-2-4-6-17)23(31-33)18-7-11-20(26)12-8-18/h2-14,22,30H,15H2,1H3/b30-16?,32-24+
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5.70n/an/an/an/an/an/an/an/a



The United States of America, as represented by the Secretary, Department of Health and Human Services

US Patent


Assay Description
Measuring its tissue levels 1 hour after administration of 10 mg/kg to mice, plasma levels were comparable after oral or i.p. administration (indicat...


US Patent US10787419 (2020)

More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Mus musculus (Mouse))
BDBM463832
PNG
(US10787419, Serial # 41)
Show SMILES CC(C)(C)OC(=O)NC(=N)C(=N/S(=O)(=O)c1ccc(Cl)cc1)\N1CC(C(=N1)c1ccc(Cl)cc1)c1ccccc1
Show InChI InChI=1S/C28H27Cl2N5O4S/c1-28(2,3)39-27(36)32-25(31)26(34-40(37,38)22-15-13-21(30)14-16-22)35-17-23(18-7-5-4-6-8-18)24(33-35)19-9-11-20(29)12-10-19/h4-16,23H,17H2,1-3H3,(H2,31,32,36)/b34-26+
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6.5n/an/an/an/an/an/an/an/a



The United States of America, as represented by the Secretary, Department of Health and Human Services

US Patent


Assay Description
Measuring its tissue levels 1 hour after administration of 10 mg/kg to mice, plasma levels were comparable after oral or i.p. administration (indicat...


US Patent US10787419 (2020)

More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Mus musculus (Mouse))
BDBM463793
PNG
(US10787419, Serial # 10E1)
Show SMILES Fc1ccc(cc1)C(=N)C(=N/S(=O)(=O)c1ccc(Cl)cc1)\N1C[C@@H](C(=N1)c1ccc(Cl)cc1)c1ccccc1
Show InChI InChI=1S/C29H21Cl2FN4O2S/c30-22-10-6-21(7-11-22)28-26(19-4-2-1-3-5-19)18-36(34-28)29(27(33)20-8-14-24(32)15-9-20)35-39(37,38)25-16-12-23(31)13-17-25/h1-17,26,33H,18H2/b33-27?,35-29+/t26-/m1/s1
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6.5n/an/an/an/an/an/an/an/a



The United States of America, as represented by the Secretary, Department of Health and Human Services

US Patent


Assay Description
Measuring its tissue levels 1 hour after administration of 10 mg/kg to mice, plasma levels were comparable after oral or i.p. administration (indicat...


US Patent US10787419 (2020)

More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Mus musculus (Mouse))
BDBM463765
PNG
(US10787419, Compound 41)
Show SMILES CC(C)(C)OC(=O)ONC(=N)N\C(=N/S(=O)(=O)c1ccc(Cl)cc1)N1CC(C(=N1)c1ccc(Cl)cc1)c1ccccc1
Show InChI InChI=1S/C28H28Cl2N6O5S/c1-28(2,3)40-27(37)41-34-25(31)32-26(35-42(38,39)22-15-13-21(30)14-16-22)36-17-23(18-7-5-4-6-8-18)24(33-36)19-9-11-20(29)12-10-19/h4-16,23H,17H2,1-3H3,(H3,31,32,34,35)
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6.5n/an/an/an/an/an/an/an/a



The United States of America, as represented by the Secretary, Department of Health and Human Services

US Patent


Assay Description
Measuring its tissue levels 1 hour after administration of 10 mg/kg to mice, plasma levels were comparable after oral or i.p. administration (indicat...


US Patent US10787419 (2020)

More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Mus musculus (Mouse))
BDBM463771
PNG
(US10787419, Compound 3)
Show SMILES CC(C)(C)C(=N)N\C(=N/S(=O)(=O)c1ccc(Cl)cc1)N1CC(C(=N1)c1ccc(Cl)cc1)c1ccccc1
Show InChI InChI=1S/C27H27Cl2N5O2S/c1-27(2,3)25(30)31-26(33-37(35,36)22-15-13-21(29)14-16-22)34-17-23(18-7-5-4-6-8-18)24(32-34)19-9-11-20(28)12-10-19/h4-16,23H,17H2,1-3H3,(H2,30,31,33)
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7n/an/an/an/an/an/an/an/a



The United States of America, as represented by the Secretary, Department of Health and Human Services

US Patent


Assay Description
Measuring its tissue levels 1 hour after administration of 10 mg/kg to mice, plasma levels were comparable after oral or i.p. administration (indicat...


US Patent US10787419 (2020)

More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Mus musculus (Mouse))
BDBM463780
PNG
(US10787419, Serial # 3)
Show SMILES CC(C)(C)C(=N)C(=N/S(=O)(=O)c1ccc(Cl)cc1)\N1CC(C(=N1)c1ccc(Cl)cc1)c1ccccc1
Show InChI InChI=1S/C27H26Cl2N4O2S/c1-27(2,3)25(30)26(32-36(34,35)22-15-13-21(29)14-16-22)33-17-23(18-7-5-4-6-8-18)24(31-33)19-9-11-20(28)12-10-19/h4-16,23,30H,17H2,1-3H3/b30-25?,32-26+
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7n/an/an/an/an/an/an/an/a



The United States of America, as represented by the Secretary, Department of Health and Human Services

US Patent


Assay Description
Measuring its tissue levels 1 hour after administration of 10 mg/kg to mice, plasma levels were comparable after oral or i.p. administration (indicat...


US Patent US10787419 (2020)

More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Mus musculus (Mouse))
BDBM463807
PNG
(US10787419, Serial # 19)
Show SMILES Fc1ccc(C(=N)C(=N/S(=O)(=O)c2ccc(Cl)cc2)\N2CC(C(=N2)c2ccc(Cl)cc2)c2ccccc2)c(F)c1
Show InChI InChI=1S/C29H20Cl2F2N4O2S/c30-20-8-6-19(7-9-20)28-25(18-4-2-1-3-5-18)17-37(35-28)29(27(34)24-15-12-22(32)16-26(24)33)36-40(38,39)23-13-10-21(31)11-14-23/h1-16,25,34H,17H2/b34-27?,36-29+
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7.70n/an/an/an/an/an/an/an/a



The United States of America, as represented by the Secretary, Department of Health and Human Services

US Patent


Assay Description
Measuring its tissue levels 1 hour after administration of 10 mg/kg to mice, plasma levels were comparable after oral or i.p. administration (indicat...


US Patent US10787419 (2020)

More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Mus musculus (Mouse))
BDBM463792
PNG
(US10787419, Serial # 10)
Show SMILES Fc1ccc(cc1)C(=N)C(=N/S(=O)(=O)c1ccc(Cl)cc1)\N1CC(C(=N1)c1ccc(Cl)cc1)c1ccccc1
Show InChI InChI=1S/C29H21Cl2FN4O2S/c30-22-10-6-21(7-11-22)28-26(19-4-2-1-3-5-19)18-36(34-28)29(27(33)20-8-14-24(32)15-9-20)35-39(37,38)25-16-12-23(31)13-17-25/h1-17,26,33H,18H2/b33-27?,35-29+
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7.90n/an/an/an/an/an/an/an/a



The United States of America, as represented by the Secretary, Department of Health and Human Services

US Patent


Assay Description
Measuring its tissue levels 1 hour after administration of 10 mg/kg to mice, plasma levels were comparable after oral or i.p. administration (indicat...


US Patent US10787419 (2020)

More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Mus musculus (Mouse))
BDBM463824
PNG
(US10787419, Serial # 33)
Show SMILES CC(=N)C(=N/S(=O)(=O)c1ccc(cc1)C1CCCC1)\N1CC(C(=N1)c1ccc(Cl)cc1)c1ccccc1
Show InChI InChI=1S/C29H29ClN4O2S/c1-20(31)29(33-37(35,36)26-17-13-22(14-18-26)21-7-5-6-8-21)34-19-27(23-9-3-2-4-10-23)28(32-34)24-11-15-25(30)16-12-24/h2-4,9-18,21,27,31H,5-8,19H2,1H3/b31-20?,33-29+
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8n/an/an/an/an/an/an/an/a



The United States of America, as represented by the Secretary, Department of Health and Human Services

US Patent


Assay Description
Measuring its tissue levels 1 hour after administration of 10 mg/kg to mice, plasma levels were comparable after oral or i.p. administration (indicat...


US Patent US10787419 (2020)

More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Mus musculus (Mouse))
BDBM463777
PNG
(US10787419, Serial # 2E1)
Show SMILES CC(=N)C(=N/S(=O)(=O)c1ccc(Cl)cc1)\N1C[C@@H](C(=N1)c1ccc(Cl)cc1)c1ccccc1
Show InChI InChI=1S/C24H20Cl2N4O2S/c1-16(27)24(29-33(31,32)21-13-11-20(26)12-14-21)30-15-22(17-5-3-2-4-6-17)23(28-30)18-7-9-19(25)10-8-18/h2-14,22,27H,15H2,1H3/b27-16?,29-24+/t22-/m1/s1
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9n/an/an/an/an/an/an/an/a



The United States of America, as represented by the Secretary, Department of Health and Human Services

US Patent


Assay Description
Measuring its tissue levels 1 hour after administration of 10 mg/kg to mice, plasma levels were comparable after oral or i.p. administration (indicat...


US Patent US10787419 (2020)

More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Mus musculus (Mouse))
BDBM463864
PNG
(US10787419, Serial # 65)
Show SMILES CC(=O)NC(=N)C(=N/S(=O)(=O)c1ccc(Cl)cc1)\N1CC(C(=N1)c1ccc(Cl)cc1)c1ccccc1
Show InChI InChI=1S/C25H21Cl2N5O3S/c1-16(33)29-24(28)25(31-36(34,35)21-13-11-20(27)12-14-21)32-15-22(17-5-3-2-4-6-17)23(30-32)18-7-9-19(26)10-8-18/h2-14,22H,15H2,1H3,(H2,28,29,33)/b31-25+
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9n/an/an/an/an/an/an/an/a



The United States of America, as represented by the Secretary, Department of Health and Human Services

US Patent


Assay Description
Measuring its tissue levels 1 hour after administration of 10 mg/kg to mice, plasma levels were comparable after oral or i.p. administration (indicat...


US Patent US10787419 (2020)

More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Mus musculus (Mouse))
BDBM463762
PNG
(US10787419, Compound 2E1)
Show SMILES CC(=N)N\C(=N/S(=O)(=O)c1ccc(Cl)cc1)N1C[C@@H](C(=N1)c1ccc(Cl)cc1)c1ccccc1
Show InChI InChI=1S/C24H21Cl2N5O2S/c1-16(27)28-24(30-34(32,33)21-13-11-20(26)12-14-21)31-15-22(17-5-3-2-4-6-17)23(29-31)18-7-9-19(25)10-8-18/h2-14,22H,15H2,1H3,(H2,27,28,30)/t22-/m1/s1
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9n/an/an/an/an/an/an/an/a



The United States of America, as represented by the Secretary, Department of Health and Human Services

US Patent


Assay Description
Measuring its tissue levels 1 hour after administration of 10 mg/kg to mice, plasma levels were comparable after oral or i.p. administration (indicat...


US Patent US10787419 (2020)

More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Mus musculus (Mouse))
BDBM463869
PNG
(US10787419, Serial # 69)
Show SMILES Cc1cc(C)n(n1)C(=N)C(=N/S(=O)(=O)c1ccc(Cl)cc1)\N1CC(C(=N1)c1ccc(Cl)cc1)c1ccccc1
Show InChI InChI=1S/C28H24Cl2N6O2S/c1-18-16-19(2)36(32-18)27(31)28(34-39(37,38)24-14-12-23(30)13-15-24)35-17-25(20-6-4-3-5-7-20)26(33-35)21-8-10-22(29)11-9-21/h3-16,25,31H,17H2,1-2H3/b31-27?,34-28+
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10n/an/an/an/an/an/an/an/a



The United States of America, as represented by the Secretary, Department of Health and Human Services

US Patent


Assay Description
Measuring its tissue levels 1 hour after administration of 10 mg/kg to mice, plasma levels were comparable after oral or i.p. administration (indicat...


US Patent US10787419 (2020)

More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Mus musculus (Mouse))
BDBM463818
PNG
(US10787419, Serial # 29)
Show SMILES CC(=N)C(=N/S(=O)(=O)c1ccc(I)cc1)\N1CC(C(=N1)c1ccc(Cl)cc1)c1ccccc1
Show InChI InChI=1S/C24H20ClIN4O2S/c1-16(27)24(29-33(31,32)21-13-11-20(26)12-14-21)30-15-22(17-5-3-2-4-6-17)23(28-30)18-7-9-19(25)10-8-18/h2-14,22,27H,15H2,1H3/b27-16?,29-24+
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10n/an/an/an/an/an/an/an/a



The United States of America, as represented by the Secretary, Department of Health and Human Services

US Patent


Assay Description
Measuring its tissue levels 1 hour after administration of 10 mg/kg to mice, plasma levels were comparable after oral or i.p. administration (indicat...


US Patent US10787419 (2020)

More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Mus musculus (Mouse))
BDBM463795
PNG
(US10787419, Serial # 11)
Show SMILES Clc1ccc(cc1)C(=N)C(=N/S(=O)(=O)c1ccc(Cl)cc1)\N1CC(C(=N1)c1ccc(Cl)cc1)c1ccccc1
Show InChI InChI=1S/C29H21Cl3N4O2S/c30-22-10-6-20(7-11-22)27(33)29(35-39(37,38)25-16-14-24(32)15-17-25)36-18-26(19-4-2-1-3-5-19)28(34-36)21-8-12-23(31)13-9-21/h1-17,26,33H,18H2/b33-27?,35-29+
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10n/an/an/an/an/an/an/an/a



The United States of America, as represented by the Secretary, Department of Health and Human Services

US Patent


Assay Description
Measuring its tissue levels 1 hour after administration of 10 mg/kg to mice, plasma levels were comparable after oral or i.p. administration (indicat...


US Patent US10787419 (2020)

More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Mus musculus (Mouse))
BDBM463862
PNG
(US10787419, Serial # 63)
Show SMILES Clc1ccc(cc1)C1=NN(CC1c1ccccc1)C(=N\S(=O)(=O)c1ccc(Cl)cc1)\C(=N)n1cccn1
Show InChI InChI=1S/C26H20Cl2N6O2S/c27-20-9-7-19(8-10-20)24-23(18-5-2-1-3-6-18)17-34(31-24)26(25(29)33-16-4-15-30-33)32-37(35,36)22-13-11-21(28)12-14-22/h1-16,23,29H,17H2/b29-25?,32-26+
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11n/an/an/an/an/an/an/an/a



The United States of America, as represented by the Secretary, Department of Health and Human Services

US Patent


Assay Description
Measuring its tissue levels 1 hour after administration of 10 mg/kg to mice, plasma levels were comparable after oral or i.p. administration (indicat...


US Patent US10787419 (2020)

More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Mus musculus (Mouse))
BDBM463770
PNG
(US10787419, Compound 4)
Show SMILES Clc1ccc(cc1)C1=NN(CC1c1ccccc1)C(\NC(=N)C1CC1)=N\S(=O)(=O)c1ccc(Cl)cc1
Show InChI InChI=1S/C26H23Cl2N5O2S/c27-20-10-8-18(9-11-20)24-23(17-4-2-1-3-5-17)16-33(31-24)26(30-25(29)19-6-7-19)32-36(34,35)22-14-12-21(28)13-15-22/h1-5,8-15,19,23H,6-7,16H2,(H2,29,30,32)
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13n/an/an/an/an/an/an/an/a



The United States of America, as represented by the Secretary, Department of Health and Human Services

US Patent


Assay Description
Measuring its tissue levels 1 hour after administration of 10 mg/kg to mice, plasma levels were comparable after oral or i.p. administration (indicat...


US Patent US10787419 (2020)

More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Mus musculus (Mouse))
BDBM463782
PNG
(US10787419, Serial # 4)
Show SMILES Clc1ccc(cc1)C1=NN(CC1c1ccccc1)C(=N\S(=O)(=O)c1ccc(Cl)cc1)\C(=N)C1CC1
Show InChI InChI=1S/C26H22Cl2N4O2S/c27-20-10-8-19(9-11-20)25-23(17-4-2-1-3-5-17)16-32(30-25)26(24(29)18-6-7-18)31-35(33,34)22-14-12-21(28)13-15-22/h1-5,8-15,18,23,29H,6-7,16H2/b29-24?,31-26+
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13n/an/an/an/an/an/an/an/a



The United States of America, as represented by the Secretary, Department of Health and Human Services

US Patent


Assay Description
Measuring its tissue levels 1 hour after administration of 10 mg/kg to mice, plasma levels were comparable after oral or i.p. administration (indicat...


US Patent US10787419 (2020)

More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Mus musculus (Mouse))
BDBM463796
PNG
(US10787419, Serial # 11E1)
Show SMILES Clc1ccc(cc1)C(=N)C(=N/S(=O)(=O)c1ccc(Cl)cc1)\N1C[C@@H](C(=N1)c1ccc(Cl)cc1)c1ccccc1
Show InChI InChI=1S/C29H21Cl3N4O2S/c30-22-10-6-20(7-11-22)27(33)29(35-39(37,38)25-16-14-24(32)15-17-25)36-18-26(19-4-2-1-3-5-19)28(34-36)21-8-12-23(31)13-9-21/h1-17,26,33H,18H2/b33-27?,35-29+/t26-/m1/s1
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15n/an/an/an/an/an/an/an/a



The United States of America, as represented by the Secretary, Department of Health and Human Services

US Patent


Assay Description
Measuring its tissue levels 1 hour after administration of 10 mg/kg to mice, plasma levels were comparable after oral or i.p. administration (indicat...


US Patent US10787419 (2020)

More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Mus musculus (Mouse))
BDBM463789
PNG
(US10787419, Serial # 7)
Show SMILES Clc1ccc(cc1)C1=NN(CC1c1ccccc1)C(=N\S(=O)(=O)c1ccc(Cl)cc1)\C12CC3CC(CC(C3)C1)C2
Show InChI InChI=1S/C32H31Cl2N3O2S/c33-26-8-6-25(7-9-26)30-29(24-4-2-1-3-5-24)20-37(35-30)31(36-40(38,39)28-12-10-27(34)11-13-28)32-17-21-14-22(18-32)16-23(15-21)19-32/h1-13,21-23,29H,14-20H2/b36-31+
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15n/an/an/an/an/an/an/an/a



The United States of America, as represented by the Secretary, Department of Health and Human Services

US Patent


Assay Description
Measuring its tissue levels 1 hour after administration of 10 mg/kg to mice, plasma levels were comparable after oral or i.p. administration (indicat...


US Patent US10787419 (2020)

More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Mus musculus (Mouse))
BDBM463871
PNG
(US10787419, Serial # 71)
Show SMILES CC(=O)NC(=N)C(=N/S(=O)(=O)c1ccc(cc1)C1CCCC1)\N1CC(C(=N1)c1ccc(Cl)cc1)c1ccccc1
Show InChI InChI=1S/C30H30ClN5O3S/c1-20(37)33-29(32)30(35-40(38,39)26-17-13-22(14-18-26)21-7-5-6-8-21)36-19-27(23-9-3-2-4-10-23)28(34-36)24-11-15-25(31)16-12-24/h2-4,9-18,21,27H,5-8,19H2,1H3,(H2,32,33,37)/b35-30+
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16n/an/an/an/an/an/an/an/a



The United States of America, as represented by the Secretary, Department of Health and Human Services

US Patent


Assay Description
Measuring its tissue levels 1 hour after administration of 10 mg/kg to mice, plasma levels were comparable after oral or i.p. administration (indicat...


US Patent US10787419 (2020)

More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Mus musculus (Mouse))
BDBM463816
PNG
(US10787419, Serial # 28)
Show SMILES CC(=N)C(=N/S(=O)(=O)c1ccc(Br)cc1)\N1CC(C(=N1)c1ccc(Cl)cc1)c1ccccc1
Show InChI InChI=1S/C24H20BrClN4O2S/c1-16(27)24(29-33(31,32)21-13-9-19(25)10-14-21)30-15-22(17-5-3-2-4-6-17)23(28-30)18-7-11-20(26)12-8-18/h2-14,22,27H,15H2,1H3/b27-16?,29-24+
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18n/an/an/an/an/an/an/an/a



The United States of America, as represented by the Secretary, Department of Health and Human Services

US Patent


Assay Description
Measuring its tissue levels 1 hour after administration of 10 mg/kg to mice, plasma levels were comparable after oral or i.p. administration (indicat...


US Patent US10787419 (2020)

More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Mus musculus (Mouse))
BDBM463776
PNG
(US10787419, Serial # 2)
Show SMILES CC(=N)C(=N/S(=O)(=O)c1ccc(Cl)cc1)\N1CC(C(=N1)c1ccc(Cl)cc1)c1ccccc1
Show InChI InChI=1S/C24H20Cl2N4O2S/c1-16(27)24(29-33(31,32)21-13-11-20(26)12-14-21)30-15-22(17-5-3-2-4-6-17)23(28-30)18-7-9-19(25)10-8-18/h2-14,22,27H,15H2,1H3/b27-16?,29-24+
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18n/an/an/an/an/an/an/an/a



The United States of America, as represented by the Secretary, Department of Health and Human Services

US Patent


Assay Description
Measuring its tissue levels 1 hour after administration of 10 mg/kg to mice, plasma levels were comparable after oral or i.p. administration (indicat...


US Patent US10787419 (2020)

More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Mus musculus (Mouse))
BDBM463761
PNG
(US10787419, Compound 2)
Show SMILES CC(=N)N\C(=N/S(=O)(=O)c1ccc(Cl)cc1)N1CC(C(=N1)c1ccc(Cl)cc1)c1ccccc1
Show InChI InChI=1S/C24H21Cl2N5O2S/c1-16(27)28-24(30-34(32,33)21-13-11-20(26)12-14-21)31-15-22(17-5-3-2-4-6-17)23(29-31)18-7-9-19(25)10-8-18/h2-14,22H,15H2,1H3,(H2,27,28,30)
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18n/an/an/an/an/an/an/an/a



The United States of America, as represented by the Secretary, Department of Health and Human Services

US Patent


Assay Description
Measuring its tissue levels 1 hour after administration of 10 mg/kg to mice, plasma levels were comparable after oral or i.p. administration (indicat...


US Patent US10787419 (2020)

More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Mus musculus (Mouse))
BDBM463803
PNG
(US10787419, Serial # 15)
Show SMILES Fc1ccccc1C(=N)C(=N/S(=O)(=O)c1ccc(Cl)cc1)\N1CC(C(=N1)c1ccc(Cl)cc1)c1ccccc1
Show InChI InChI=1S/C29H21Cl2FN4O2S/c30-21-12-10-20(11-13-21)28-25(19-6-2-1-3-7-19)18-36(34-28)29(27(33)24-8-4-5-9-26(24)32)35-39(37,38)23-16-14-22(31)15-17-23/h1-17,25,33H,18H2/b33-27?,35-29+
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19n/an/an/an/an/an/an/an/a



The United States of America, as represented by the Secretary, Department of Health and Human Services

US Patent


Assay Description
Measuring its tissue levels 1 hour after administration of 10 mg/kg to mice, plasma levels were comparable after oral or i.p. administration (indicat...


US Patent US10787419 (2020)

More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Mus musculus (Mouse))
BDBM463833
PNG
(US10787419, Serial # 42 | US10787419, Serial # 43)
Show SMILES COCCN(C)C(=N)C(=N/S(=O)(=O)c1ccc(Cl)cc1)\N1CC(C(=N1)c1ccc(Cl)cc1)c1ccccc1
Show InChI InChI=1S/C27H27Cl2N5O3S/c1-33(16-17-37-2)26(30)27(32-38(35,36)23-14-12-22(29)13-15-23)34-18-24(19-6-4-3-5-7-19)25(31-34)20-8-10-21(28)11-9-20/h3-15,24,30H,16-18H2,1-2H3/b30-26?,32-27+
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23n/an/an/an/an/an/an/an/a



The United States of America, as represented by the Secretary, Department of Health and Human Services

US Patent


Assay Description
Measuring its tissue levels 1 hour after administration of 10 mg/kg to mice, plasma levels were comparable after oral or i.p. administration (indicat...


US Patent US10787419 (2020)

More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Mus musculus (Mouse))
BDBM463806
PNG
(US10787419, Serial # 18)
Show SMILES Clc1ccc(cc1)C1=NN(CC1c1ccccc1)C(=N\S(=O)(=O)c1ccc(Cl)cc1)\C(=N)c1ccccn1
Show InChI InChI=1S/C28H21Cl2N5O2S/c29-21-11-9-20(10-12-21)27-24(19-6-2-1-3-7-19)18-35(33-27)28(26(31)25-8-4-5-17-32-25)34-38(36,37)23-15-13-22(30)14-16-23/h1-17,24,31H,18H2/b31-26?,34-28+
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26n/an/an/an/an/an/an/an/a



The United States of America, as represented by the Secretary, Department of Health and Human Services

US Patent


Assay Description
Measuring its tissue levels 1 hour after administration of 10 mg/kg to mice, plasma levels were comparable after oral or i.p. administration (indicat...


US Patent US10787419 (2020)

More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Mus musculus (Mouse))
BDBM463764
PNG
(US10787419, Compound 8)
Show SMILES Clc1ccc(cc1)C1=NN(CC1c1ccccc1)C(\NC(=N)c1ccccc1)=N\S(=O)(=O)c1ccc(Cl)cc1
Show InChI InChI=1S/C29H23Cl2N5O2S/c30-23-13-11-21(12-14-23)27-26(20-7-3-1-4-8-20)19-36(34-27)29(33-28(32)22-9-5-2-6-10-22)35-39(37,38)25-17-15-24(31)16-18-25/h1-18,26H,19H2,(H2,32,33,35)
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26n/an/an/an/an/an/an/an/a



The United States of America, as represented by the Secretary, Department of Health and Human Services

US Patent


Assay Description
Measuring its tissue levels 1 hour after administration of 10 mg/kg to mice, plasma levels were comparable after oral or i.p. administration (indicat...


US Patent US10787419 (2020)

More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Mus musculus (Mouse))
BDBM463790
PNG
(US10787419, Serial # 8)
Show SMILES Clc1ccc(cc1)C1=NN(CC1c1ccccc1)C(=N\S(=O)(=O)c1ccc(Cl)cc1)\C(=N)c1ccccc1
Show InChI InChI=1S/C29H22Cl2N4O2S/c30-23-13-11-22(12-14-23)28-26(20-7-3-1-4-8-20)19-35(33-28)29(27(32)21-9-5-2-6-10-21)34-38(36,37)25-17-15-24(31)16-18-25/h1-18,26,32H,19H2/b32-27?,34-29+
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26n/an/an/an/an/an/an/an/a



The United States of America, as represented by the Secretary, Department of Health and Human Services

US Patent


Assay Description
Measuring its tissue levels 1 hour after administration of 10 mg/kg to mice, plasma levels were comparable after oral or i.p. administration (indicat...


US Patent US10787419 (2020)

More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Mus musculus (Mouse))
BDBM463802
PNG
(US10787419, Serial # 14 | US10787419, Serial # 20)
Show SMILES Clc1ccc(cc1)C1=NN(CC1c1ccccc1)C(=N\S(=O)(=O)c1ccc(Cl)cc1)\C(=N)c1ccc(Br)cc1
Show InChI InChI=1S/C29H21BrCl2N4O2S/c30-22-10-6-20(7-11-22)27(33)29(35-39(37,38)25-16-14-24(32)15-17-25)36-18-26(19-4-2-1-3-5-19)28(34-36)21-8-12-23(31)13-9-21/h1-17,26,33H,18H2/b33-27?,35-29+
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27n/an/an/an/an/an/an/an/a



The United States of America, as represented by the Secretary, Department of Health and Human Services

US Patent


Assay Description
Measuring its tissue levels 1 hour after administration of 10 mg/kg to mice, plasma levels were comparable after oral or i.p. administration (indicat...


US Patent US10787419 (2020)

More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Mus musculus (Mouse))
BDBM463787
PNG
(US10787419, Serial # 5)
Show SMILES CC(C)C(=N)C(=N/S(=O)(=O)c1ccc(Cl)cc1)\N1CC(C(=N1)c1ccc(Cl)cc1)c1ccccc1
Show InChI InChI=1S/C26H24Cl2N4O2S/c1-17(2)24(29)26(31-35(33,34)22-14-12-21(28)13-15-22)32-16-23(18-6-4-3-5-7-18)25(30-32)19-8-10-20(27)11-9-19/h3-15,17,23,29H,16H2,1-2H3/b29-24?,31-26+
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29n/an/an/an/an/an/an/an/a



The United States of America, as represented by the Secretary, Department of Health and Human Services

US Patent


Assay Description
Measuring its tissue levels 1 hour after administration of 10 mg/kg to mice, plasma levels were comparable after oral or i.p. administration (indicat...


US Patent US10787419 (2020)

More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Mus musculus (Mouse))
BDBM463788
PNG
(US10787419, Serial # 6)
Show SMILES Clc1ccc(cc1)C1=NN(CC1c1ccccc1)C(=N\S(=O)(=O)c1ccc(Cl)cc1)\C1NCCCC1=N
Show InChI InChI=1S/C27H25Cl2N5O2S/c28-20-10-8-19(9-11-20)25-23(18-5-2-1-3-6-18)17-34(32-25)27(26-24(30)7-4-16-31-26)33-37(35,36)22-14-12-21(29)13-15-22/h1-3,5-6,8-15,23,26,30-31H,4,7,16-17H2/b30-24?,33-27+
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29n/an/an/an/an/an/an/an/a



The United States of America, as represented by the Secretary, Department of Health and Human Services

US Patent


Assay Description
Measuring its tissue levels 1 hour after administration of 10 mg/kg to mice, plasma levels were comparable after oral or i.p. administration (indicat...


US Patent US10787419 (2020)

More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Mus musculus (Mouse))
BDBM463766
PNG
(US10787419, Compound 73)
Show SMILES NN\C(=N/S(=O)(=O)c1ccc(Cl)cc1)N1CC(C(=N1)c1ccc(Cl)cc1)c1ccccc1
Show InChI InChI=1S/C22H19Cl2N5O2S/c23-17-8-6-16(7-9-17)21-20(15-4-2-1-3-5-15)14-29(27-21)22(26-25)28-32(30,31)19-12-10-18(24)11-13-19/h1-13,20H,14,25H2,(H,26,28)
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33n/an/an/an/an/an/an/an/a



The United States of America, as represented by the Secretary, Department of Health and Human Services

US Patent


Assay Description
Measuring its tissue levels 1 hour after administration of 10 mg/kg to mice, plasma levels were comparable after oral or i.p. administration (indicat...


US Patent US10787419 (2020)

More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Mus musculus (Mouse))
BDBM463873
PNG
(US10787419, Serial # 73)
Show SMILES NC(=N)C(=N/S(=O)(=O)c1ccc(Cl)cc1)\N1CC(C(=N1)c1ccc(Cl)cc1)c1ccccc1
Show InChI InChI=1S/C23H19Cl2N5O2S/c24-17-8-6-16(7-9-17)21-20(15-4-2-1-3-5-15)14-30(28-21)23(22(26)27)29-33(31,32)19-12-10-18(25)11-13-19/h1-13,20H,14H2,(H3,26,27)/b29-23+
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33n/an/an/an/an/an/an/an/a



The United States of America, as represented by the Secretary, Department of Health and Human Services

US Patent


Assay Description
Measuring its tissue levels 1 hour after administration of 10 mg/kg to mice, plasma levels were comparable after oral or i.p. administration (indicat...


US Patent US10787419 (2020)

More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Mus musculus (Mouse))
BDBM463767
PNG
(US10787419, Compound 12)
Show SMILES Clc1ccc(cc1)C1=NN(CC1c1ccccc1)C(\NC(=N)c1ccncc1)=N\S(=O)(=O)c1ccc(Cl)cc1
Show InChI InChI=1S/C28H22Cl2N6O2S/c29-22-8-6-20(7-9-22)26-25(19-4-2-1-3-5-19)18-36(34-26)28(33-27(31)21-14-16-32-17-15-21)35-39(37,38)24-12-10-23(30)11-13-24/h1-17,25H,18H2,(H2,31,33,35)
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34n/an/an/an/an/an/an/an/a



The United States of America, as represented by the Secretary, Department of Health and Human Services

US Patent


Assay Description
Measuring its tissue levels 1 hour after administration of 10 mg/kg to mice, plasma levels were comparable after oral or i.p. administration (indicat...


US Patent US10787419 (2020)

More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Mus musculus (Mouse))
BDBM463800
PNG
(US10787419, Serial # 12)
Show SMILES Clc1ccc(cc1)C1=NN(CC1c1ccccc1)C(=N\S(=O)(=O)c1ccc(Cl)cc1)\C(=N)c1ccncc1
Show InChI InChI=1S/C28H21Cl2N5O2S/c29-22-8-6-21(7-9-22)27-25(19-4-2-1-3-5-19)18-35(33-27)28(26(31)20-14-16-32-17-15-20)34-38(36,37)24-12-10-23(30)11-13-24/h1-17,25,31H,18H2/b31-26?,34-28+
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34n/an/an/an/an/an/an/an/a



The United States of America, as represented by the Secretary, Department of Health and Human Services

US Patent


Assay Description
Measuring its tissue levels 1 hour after administration of 10 mg/kg to mice, plasma levels were comparable after oral or i.p. administration (indicat...


US Patent US10787419 (2020)

More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Mus musculus (Mouse))
BDBM463763
PNG
(US10787419, Compound 2E2)
Show SMILES CC(=N)N\C(=N/S(=O)(=O)c1ccc(Cl)cc1)N1C[C@H](C(=N1)c1ccc(Cl)cc1)c1ccccc1
Show InChI InChI=1S/C24H21Cl2N5O2S/c1-16(27)28-24(30-34(32,33)21-13-11-20(26)12-14-21)31-15-22(17-5-3-2-4-6-17)23(29-31)18-7-9-19(25)10-8-18/h2-14,22H,15H2,1H3,(H2,27,28,30)/t22-/m0/s1
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48n/an/an/an/an/an/an/an/a



The United States of America, as represented by the Secretary, Department of Health and Human Services

US Patent


Assay Description
Measuring its tissue levels 1 hour after administration of 10 mg/kg to mice, plasma levels were comparable after oral or i.p. administration (indicat...


US Patent US10787419 (2020)

More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Mus musculus (Mouse))
BDBM463829
PNG
(US10787419, Serial # 38)
Show SMILES CCN(CC)C(=N)C(=N/S(=O)(=O)c1ccc(Cl)cc1)\N1CC(C(=N1)c1ccc(Cl)cc1)c1ccccc1
Show InChI InChI=1S/C27H27Cl2N5O2S/c1-3-33(4-2)26(30)27(32-37(35,36)23-16-14-22(29)15-17-23)34-18-24(19-8-6-5-7-9-19)25(31-34)20-10-12-21(28)13-11-20/h5-17,24,30H,3-4,18H2,1-2H3/b30-26?,32-27+
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49n/an/an/an/an/an/an/an/a



The United States of America, as represented by the Secretary, Department of Health and Human Services

US Patent


Assay Description
Measuring its tissue levels 1 hour after administration of 10 mg/kg to mice, plasma levels were comparable after oral or i.p. administration (indicat...


US Patent US10787419 (2020)

More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Mus musculus (Mouse))
BDBM463840
PNG
(US10787419, Serial # 46)
Show SMILES CC(C)(C)NC(=N)C(=N/S(=O)(=O)c1ccc(Cl)cc1)\N1CC(C(=N1)c1ccc(Cl)cc1)c1ccccc1
Show InChI InChI=1S/C27H27Cl2N5O2S/c1-27(2,3)31-25(30)26(33-37(35,36)22-15-13-21(29)14-16-22)34-17-23(18-7-5-4-6-8-18)24(32-34)19-9-11-20(28)12-10-19/h4-16,23H,17H2,1-3H3,(H2,30,31)/b33-26+
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49n/an/an/an/an/an/an/an/a



The United States of America, as represented by the Secretary, Department of Health and Human Services

US Patent


Assay Description
Measuring its tissue levels 1 hour after administration of 10 mg/kg to mice, plasma levels were comparable after oral or i.p. administration (indicat...


US Patent US10787419 (2020)

More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Mus musculus (Mouse))
BDBM463802
PNG
(US10787419, Serial # 14 | US10787419, Serial # 20)
Show SMILES Clc1ccc(cc1)C1=NN(CC1c1ccccc1)C(=N\S(=O)(=O)c1ccc(Cl)cc1)\C(=N)c1ccc(Br)cc1
Show InChI InChI=1S/C29H21BrCl2N4O2S/c30-22-10-6-20(7-11-22)27(33)29(35-39(37,38)25-16-14-24(32)15-17-25)36-18-26(19-4-2-1-3-5-19)28(34-36)21-8-12-23(31)13-9-21/h1-17,26,33H,18H2/b33-27?,35-29+
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56n/an/an/an/an/an/an/an/a



The United States of America, as represented by the Secretary, Department of Health and Human Services

US Patent


Assay Description
Measuring its tissue levels 1 hour after administration of 10 mg/kg to mice, plasma levels were comparable after oral or i.p. administration (indicat...


US Patent US10787419 (2020)

More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Mus musculus (Mouse))
BDBM463804
PNG
(US10787419, Serial # 16)
Show SMILES Clc1ccc(cc1)C1=NN(CC1c1ccccc1)C(=N\S(=O)(=O)c1ccc(Cl)cc1)\C(=N)c1cccs1
Show InChI InChI=1S/C27H20Cl2N4O2S2/c28-20-10-8-19(9-11-20)26-23(18-5-2-1-3-6-18)17-33(31-26)27(25(30)24-7-4-16-36-24)32-37(34,35)22-14-12-21(29)13-15-22/h1-16,23,30H,17H2/b30-25?,32-27+
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60n/an/an/an/an/an/an/an/a



The United States of America, as represented by the Secretary, Department of Health and Human Services

US Patent


Assay Description
Measuring its tissue levels 1 hour after administration of 10 mg/kg to mice, plasma levels were comparable after oral or i.p. administration (indicat...


US Patent US10787419 (2020)

More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Mus musculus (Mouse))
BDBM463815
PNG
(US10787419, Serial # 27)
Show SMILES CC(=N)C(=N/S(=O)(=O)c1ccc(F)cc1)\N1CC(C(=N1)c1ccc(Cl)cc1)c1ccccc1
Show InChI InChI=1S/C24H20ClFN4O2S/c1-16(27)24(29-33(31,32)21-13-11-20(26)12-14-21)30-15-22(17-5-3-2-4-6-17)23(28-30)18-7-9-19(25)10-8-18/h2-14,22,27H,15H2,1H3/b27-16?,29-24+
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60n/an/an/an/an/an/an/an/a



The United States of America, as represented by the Secretary, Department of Health and Human Services

US Patent


Assay Description
Measuring its tissue levels 1 hour after administration of 10 mg/kg to mice, plasma levels were comparable after oral or i.p. administration (indicat...


US Patent US10787419 (2020)

More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Mus musculus (Mouse))
BDBM463791
PNG
(US10787419, Serial # 9)
Show SMILES [O-][N+](=O)c1ccc(cc1)C(=N)C(=N/S(=O)(=O)c1ccc(Cl)cc1)\N1CC(C(=N1)c1ccc(Cl)cc1)c1ccccc1
Show InChI InChI=1S/C29H21Cl2N5O4S/c30-22-10-6-21(7-11-22)28-26(19-4-2-1-3-5-19)18-35(33-28)29(27(32)20-8-14-24(15-9-20)36(37)38)34-41(39,40)25-16-12-23(31)13-17-25/h1-17,26,32H,18H2/b32-27?,34-29+
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62n/an/an/an/an/an/an/an/a



The United States of America, as represented by the Secretary, Department of Health and Human Services

US Patent


Assay Description
Measuring its tissue levels 1 hour after administration of 10 mg/kg to mice, plasma levels were comparable after oral or i.p. administration (indicat...


US Patent US10787419 (2020)

More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Mus musculus (Mouse))
BDBM463810
PNG
(US10787419, Serial # 22)
Show SMILES CCSC(=N)C(=N/S(=O)(=O)c1ccc(Cl)cc1)\N1CC(C(=N1)c1ccc(Cl)cc1)c1ccccc1
Show InChI InChI=1S/C25H22Cl2N4O2S2/c1-2-34-24(28)25(30-35(32,33)21-14-12-20(27)13-15-21)31-16-22(17-6-4-3-5-7-17)23(29-31)18-8-10-19(26)11-9-18/h3-15,22,28H,2,16H2,1H3/b28-24?,30-25+
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67n/an/an/an/an/an/an/an/a



The United States of America, as represented by the Secretary, Department of Health and Human Services

US Patent


Assay Description
Measuring its tissue levels 1 hour after administration of 10 mg/kg to mice, plasma levels were comparable after oral or i.p. administration (indicat...


US Patent US10787419 (2020)

More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Mus musculus (Mouse))
BDBM463809
PNG
(US10787419, Serial # 21)
Show SMILES CSC(=N)C(=N/S(=O)(=O)c1ccc(Cl)cc1)\N1CC(C(=N1)c1ccc(Cl)cc1)c1ccccc1
Show InChI InChI=1S/C24H20Cl2N4O2S2/c1-33-23(27)24(29-34(31,32)20-13-11-19(26)12-14-20)30-15-21(16-5-3-2-4-6-16)22(28-30)17-7-9-18(25)10-8-17/h2-14,21,27H,15H2,1H3/b27-23?,29-24+
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67n/an/an/an/an/an/an/an/a



The United States of America, as represented by the Secretary, Department of Health and Human Services

US Patent


Assay Description
Measuring its tissue levels 1 hour after administration of 10 mg/kg to mice, plasma levels were comparable after oral or i.p. administration (indicat...


US Patent US10787419 (2020)

More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Mus musculus (Mouse))
BDBM463801
PNG
(US10787419, Serial # 13)
Show SMILES Clc1ccc(cc1)C1=NN(CC1c1ccccc1)C(=N\S(=O)(=O)c1ccc(Cl)cc1)\C(=N)COc1ccccc1
Show InChI InChI=1S/C30H24Cl2N4O3S/c31-23-13-11-22(12-14-23)29-27(21-7-3-1-4-8-21)19-36(34-29)30(28(33)20-39-25-9-5-2-6-10-25)35-40(37,38)26-17-15-24(32)16-18-26/h1-18,27,33H,19-20H2/b33-28?,35-30+
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72n/an/an/an/an/an/an/an/a



The United States of America, as represented by the Secretary, Department of Health and Human Services

US Patent


Assay Description
Measuring its tissue levels 1 hour after administration of 10 mg/kg to mice, plasma levels were comparable after oral or i.p. administration (indicat...


US Patent US10787419 (2020)

More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Mus musculus (Mouse))
BDBM463805
PNG
(US10787419, Serial # 17)
Show SMILES COc1cccc(c1)C(=N)C(=N/S(=O)(=O)c1ccc(Cl)cc1)\N1CC(C(=N1)c1ccc(Cl)cc1)c1ccccc1
Show InChI InChI=1S/C30H24Cl2N4O3S/c1-39-25-9-5-8-22(18-25)28(33)30(35-40(37,38)26-16-14-24(32)15-17-26)36-19-27(20-6-3-2-4-7-20)29(34-36)21-10-12-23(31)13-11-21/h2-18,27,33H,19H2,1H3/b33-28?,35-30+
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86n/an/an/an/an/an/an/an/a



The United States of America, as represented by the Secretary, Department of Health and Human Services

US Patent


Assay Description
Measuring its tissue levels 1 hour after administration of 10 mg/kg to mice, plasma levels were comparable after oral or i.p. administration (indicat...


US Patent US10787419 (2020)

More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Mus musculus (Mouse))
BDBM463821
PNG
(US10787419, Serial # 31)
Show SMILES CC(=N)C(=N/S(=O)(=O)c1ccc(C)cc1)\N1CC(C(=N1)c1ccc(Cl)cc1)c1ccccc1
Show InChI InChI=1S/C25H23ClN4O2S/c1-17-8-14-22(15-9-17)33(31,32)29-25(18(2)27)30-16-23(19-6-4-3-5-7-19)24(28-30)20-10-12-21(26)13-11-20/h3-15,23,27H,16H2,1-2H3/b27-18?,29-25+
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87n/an/an/an/an/an/an/an/a



The United States of America, as represented by the Secretary, Department of Health and Human Services

US Patent


Assay Description
Measuring its tissue levels 1 hour after administration of 10 mg/kg to mice, plasma levels were comparable after oral or i.p. administration (indicat...


US Patent US10787419 (2020)

More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Mus musculus (Mouse))
BDBM463866
PNG
(US10787419, Serial # 66)
Show SMILES CC(C)(NC(=N)C(=N/S(=O)(=O)c1ccc(Cl)cc1)\N1CC(C(=N1)c1ccc(Cl)cc1)c1ccccc1)c1ccccc1
Show InChI InChI=1S/C32H29Cl2N5O2S/c1-32(2,24-11-7-4-8-12-24)36-30(35)31(38-42(40,41)27-19-17-26(34)18-20-27)39-21-28(22-9-5-3-6-10-22)29(37-39)23-13-15-25(33)16-14-23/h3-20,28H,21H2,1-2H3,(H2,35,36)/b38-31+
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112n/an/an/an/an/an/an/an/a



The United States of America, as represented by the Secretary, Department of Health and Human Services

US Patent


Assay Description
Measuring its tissue levels 1 hour after administration of 10 mg/kg to mice, plasma levels were comparable after oral or i.p. administration (indicat...


US Patent US10787419 (2020)

More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Mus musculus (Mouse))
BDBM463820
PNG
(US10787419, Serial # 30)
Show SMILES CC(=N)C(=N/S(=O)(=O)c1ccccc1)\N1CC(C(=N1)c1ccc(Cl)cc1)c1ccccc1
Show InChI InChI=1S/C24H21ClN4O2S/c1-17(26)24(28-32(30,31)21-10-6-3-7-11-21)29-16-22(18-8-4-2-5-9-18)23(27-29)19-12-14-20(25)15-13-19/h2-15,22,26H,16H2,1H3/b26-17?,28-24+
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114n/an/an/an/an/an/an/an/a



The United States of America, as represented by the Secretary, Department of Health and Human Services

US Patent


Assay Description
Measuring its tissue levels 1 hour after administration of 10 mg/kg to mice, plasma levels were comparable after oral or i.p. administration (indicat...


US Patent US10787419 (2020)

More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Mus musculus (Mouse))
BDBM463812
PNG
(US10787419, Serial # 24)
Show SMILES Clc1ccc(cc1)C1=NN(CC1c1ccccc1)C(=N\S(=O)(=O)c1ccc(Cl)cc1)\C(=N)SCc1ccccc1
Show InChI InChI=1S/C30H24Cl2N4O2S2/c31-24-13-11-23(12-14-24)28-27(22-9-5-2-6-10-22)19-36(34-28)30(29(33)39-20-21-7-3-1-4-8-21)35-40(37,38)26-17-15-25(32)16-18-26/h1-18,27,33H,19-20H2/b33-29?,35-30+
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127n/an/an/an/an/an/an/an/a



The United States of America, as represented by the Secretary, Department of Health and Human Services

US Patent


Assay Description
Measuring its tissue levels 1 hour after administration of 10 mg/kg to mice, plasma levels were comparable after oral or i.p. administration (indicat...


US Patent US10787419 (2020)

More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Mus musculus (Mouse))
BDBM463828
PNG
(US10787419, Serial # 37)
Show SMILES CCCN(CCC)C(=N)C(=N/S(=O)(=O)c1ccc(Cl)cc1)\N1CC(C(=N1)c1ccc(Cl)cc1)c1ccccc1
Show InChI InChI=1S/C29H31Cl2N5O2S/c1-3-18-35(19-4-2)28(32)29(34-39(37,38)25-16-14-24(31)15-17-25)36-20-26(21-8-6-5-7-9-21)27(33-36)22-10-12-23(30)13-11-22/h5-17,26,32H,3-4,18-20H2,1-2H3/b32-28?,34-29+
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138n/an/an/an/an/an/an/an/a



The United States of America, as represented by the Secretary, Department of Health and Human Services

US Patent


Assay Description
Measuring its tissue levels 1 hour after administration of 10 mg/kg to mice, plasma levels were comparable after oral or i.p. administration (indicat...


US Patent US10787419 (2020)

More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Mus musculus (Mouse))
BDBM463847
PNG
(US10787419, Serial # 48)
Show SMILES CN(Cc1cccnc1)C(=N)C(=N/S(=O)(=O)c1ccc(Cl)cc1)\N1CC(C(=N1)c1ccc(Cl)cc1)c1ccccc1
Show InChI InChI=1S/C30H26Cl2N6O2S/c1-37(19-21-6-5-17-34-18-21)29(33)30(36-41(39,40)26-15-13-25(32)14-16-26)38-20-27(22-7-3-2-4-8-22)28(35-38)23-9-11-24(31)12-10-23/h2-18,27,33H,19-20H2,1H3/b33-29?,36-30+
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147n/an/an/an/an/an/an/an/a



The United States of America, as represented by the Secretary, Department of Health and Human Services

US Patent


Assay Description
Measuring its tissue levels 1 hour after administration of 10 mg/kg to mice, plasma levels were comparable after oral or i.p. administration (indicat...


US Patent US10787419 (2020)

More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Mus musculus (Mouse))
BDBM463811
PNG
(US10787419, Serial # 23)
Show SMILES CC(C)SC(=N)C(=N/S(=O)(=O)c1ccc(Cl)cc1)\N1CC(C(=N1)c1ccc(Cl)cc1)c1ccccc1
Show InChI InChI=1S/C26H24Cl2N4O2S2/c1-17(2)35-25(29)26(31-36(33,34)22-14-12-21(28)13-15-22)32-16-23(18-6-4-3-5-7-18)24(30-32)19-8-10-20(27)11-9-19/h3-15,17,23,29H,16H2,1-2H3/b29-25?,31-26+
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166n/an/an/an/an/an/an/an/a



The United States of America, as represented by the Secretary, Department of Health and Human Services

US Patent


Assay Description
Measuring its tissue levels 1 hour after administration of 10 mg/kg to mice, plasma levels were comparable after oral or i.p. administration (indicat...


US Patent US10787419 (2020)

More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Mus musculus (Mouse))
BDBM463774
PNG
(US10787419, Compound 44)
Show SMILES CN(C)C(=N)N\C(=N/S(=O)(=O)c1ccc(Cl)cc1)N1CC(C(=N1)c1ccc(Cl)cc1)c1ccccc1
Show InChI InChI=1S/C25H24Cl2N6O2S/c1-32(2)24(28)29-25(31-36(34,35)21-14-12-20(27)13-15-21)33-16-22(17-6-4-3-5-7-17)23(30-33)18-8-10-19(26)11-9-18/h3-15,22H,16H2,1-2H3,(H2,28,29,31)
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171n/an/an/an/an/an/an/an/a



The United States of America, as represented by the Secretary, Department of Health and Human Services

US Patent


Assay Description
Measuring its tissue levels 1 hour after administration of 10 mg/kg to mice, plasma levels were comparable after oral or i.p. administration (indicat...


US Patent US10787419 (2020)

More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Mus musculus (Mouse))
BDBM463837
PNG
(US10787419, Serial # 44)
Show SMILES CN(C)C(=N)C(=N/S(=O)(=O)c1ccc(Cl)cc1)\N1CC(C(=N1)c1ccc(Cl)cc1)c1ccccc1
Show InChI InChI=1S/C25H23Cl2N5O2S/c1-31(2)24(28)25(30-35(33,34)21-14-12-20(27)13-15-21)32-16-22(17-6-4-3-5-7-17)23(29-32)18-8-10-19(26)11-9-18/h3-15,22,28H,16H2,1-2H3/b28-24?,30-25+
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171n/an/an/an/an/an/an/an/a



The United States of America, as represented by the Secretary, Department of Health and Human Services

US Patent


Assay Description
Measuring its tissue levels 1 hour after administration of 10 mg/kg to mice, plasma levels were comparable after oral or i.p. administration (indicat...


US Patent US10787419 (2020)

More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Mus musculus (Mouse))
BDBM463822
PNG
(US10787419, Serial # 32)
Show SMILES COc1ccc(cc1)S(=O)(=O)\N=C(\N1CC(C(=N1)c1ccc(Cl)cc1)c1ccccc1)C(C)=N
Show InChI InChI=1S/C25H23ClN4O3S/c1-17(27)25(29-34(31,32)22-14-12-21(33-2)13-15-22)30-16-23(18-6-4-3-5-7-18)24(28-30)19-8-10-20(26)11-9-19/h3-15,23,27H,16H2,1-2H3/b27-17?,29-25+
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182n/an/an/an/an/an/an/an/a



The United States of America, as represented by the Secretary, Department of Health and Human Services

US Patent


Assay Description
Measuring its tissue levels 1 hour after administration of 10 mg/kg to mice, plasma levels were comparable after oral or i.p. administration (indicat...


US Patent US10787419 (2020)

More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Mus musculus (Mouse))
BDBM463779
PNG
(US10787419, Serial # 2E2)
Show SMILES CC(=N)C(=N/S(=O)(=O)c1ccc(Cl)cc1)\N1C[C@H](C(=N1)c1ccc(Cl)cc1)c1ccccc1
Show InChI InChI=1S/C24H20Cl2N4O2S/c1-16(27)24(29-33(31,32)21-13-11-20(26)12-14-21)30-15-22(17-5-3-2-4-6-17)23(28-30)18-7-9-19(25)10-8-18/h2-14,22,27H,15H2,1H3/b27-16?,29-24+/t22-/m0/s1
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182n/an/an/an/an/an/an/an/a



The United States of America, as represented by the Secretary, Department of Health and Human Services

US Patent


Assay Description
Measuring its tissue levels 1 hour after administration of 10 mg/kg to mice, plasma levels were comparable after oral or i.p. administration (indicat...


US Patent US10787419 (2020)

More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Mus musculus (Mouse))
BDBM463814
PNG
(US10787419, Serial # 26)
Show SMILES Clc1ccc(cc1)C1=NN(CC1c1ccccc1)C(=N\S(=O)(=O)c1ccc(Cl)cc1)\C(=N)SCCCc1ccccc1
Show InChI InChI=1S/C32H28Cl2N4O2S2/c33-26-15-13-25(14-16-26)30-29(24-11-5-2-6-12-24)22-38(36-30)32(37-42(39,40)28-19-17-27(34)18-20-28)31(35)41-21-7-10-23-8-3-1-4-9-23/h1-6,8-9,11-20,29,35H,7,10,21-22H2/b35-31?,37-32+
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190n/an/an/an/an/an/an/an/a



The United States of America, as represented by the Secretary, Department of Health and Human Services

US Patent


Assay Description
Measuring its tissue levels 1 hour after administration of 10 mg/kg to mice, plasma levels were comparable after oral or i.p. administration (indicat...


US Patent US10787419 (2020)

More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Mus musculus (Mouse))
BDBM463851
PNG
(US10787419, Serial # 52)
Show SMILES Clc1ccc(cc1)C1=NN(CC1c1ccccc1)C(=N\S(=O)(=O)c1ccc(Cl)cc1)\C(=N)N1CCOCC1
Show InChI InChI=1S/C27H25Cl2N5O3S/c28-21-8-6-20(7-9-21)25-24(19-4-2-1-3-5-19)18-34(31-25)27(26(30)33-14-16-37-17-15-33)32-38(35,36)23-12-10-22(29)11-13-23/h1-13,24,30H,14-18H2/b30-26?,32-27+
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193n/an/an/an/an/an/an/an/a



The United States of America, as represented by the Secretary, Department of Health and Human Services

US Patent


Assay Description
Measuring its tissue levels 1 hour after administration of 10 mg/kg to mice, plasma levels were comparable after oral or i.p. administration (indicat...


US Patent US10787419 (2020)

More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Mus musculus (Mouse))
BDBM463772
PNG
(US10787419, Compound 52)
Show SMILES Clc1ccc(cc1)C1=NN(CC1c1ccccc1)C(\NC(=N)C1CCOCC1)=N\S(=O)(=O)c1ccc(Cl)cc1
Show InChI InChI=1S/C28H27Cl2N5O3S/c29-22-8-6-20(7-9-22)26-25(19-4-2-1-3-5-19)18-35(33-26)28(32-27(31)21-14-16-38-17-15-21)34-39(36,37)24-12-10-23(30)11-13-24/h1-13,21,25H,14-18H2,(H2,31,32,34)
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193n/an/an/an/an/an/an/an/a



The United States of America, as represented by the Secretary, Department of Health and Human Services

US Patent


Assay Description
Measuring its tissue levels 1 hour after administration of 10 mg/kg to mice, plasma levels were comparable after oral or i.p. administration (indicat...


US Patent US10787419 (2020)

More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Mus musculus (Mouse))
BDBM463860
PNG
(US10787419, Serial # 61)
Show SMILES CN(CCC#N)C(=N)C(=N/S(=O)(=O)c1ccc(Cl)cc1)\N1CC(C(=N1)c1ccc(Cl)cc1)c1ccccc1
Show InChI InChI=1S/C27H24Cl2N6O2S/c1-34(17-5-16-30)26(31)27(33-38(36,37)23-14-12-22(29)13-15-23)35-18-24(19-6-3-2-4-7-19)25(32-35)20-8-10-21(28)11-9-20/h2-4,6-15,24,31H,5,17-18H2,1H3/b31-26?,33-27+
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203n/an/an/an/an/an/an/an/a



The United States of America, as represented by the Secretary, Department of Health and Human Services

US Patent


Assay Description
Measuring its tissue levels 1 hour after administration of 10 mg/kg to mice, plasma levels were comparable after oral or i.p. administration (indicat...


US Patent US10787419 (2020)

More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Mus musculus (Mouse))
BDBM463773
PNG
(US10787419, Compound 55)
Show SMILES Clc1ccc(cc1)C1=NN(CC1c1ccccc1)C(\NC(=N)N1CCCC1)=N\S(=O)(=O)c1ccc(Cl)cc1
Show InChI InChI=1S/C27H26Cl2N6O2S/c28-21-10-8-20(9-11-21)25-24(19-6-2-1-3-7-19)18-35(32-25)27(31-26(30)34-16-4-5-17-34)33-38(36,37)23-14-12-22(29)13-15-23/h1-3,6-15,24H,4-5,16-18H2,(H2,30,31,33)
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241n/an/an/an/an/an/an/an/a



The United States of America, as represented by the Secretary, Department of Health and Human Services

US Patent


Assay Description
Measuring its tissue levels 1 hour after administration of 10 mg/kg to mice, plasma levels were comparable after oral or i.p. administration (indicat...


US Patent US10787419 (2020)

More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Mus musculus (Mouse))
BDBM463854
PNG
(US10787419, Serial # 55)
Show SMILES Clc1ccc(cc1)C1=NN(CC1c1ccccc1)C(=N\S(=O)(=O)c1ccc(Cl)cc1)\C(=N)N1CCCC1
Show InChI InChI=1S/C27H25Cl2N5O2S/c28-21-10-8-20(9-11-21)25-24(19-6-2-1-3-7-19)18-34(31-25)27(26(30)33-16-4-5-17-33)32-37(35,36)23-14-12-22(29)13-15-23/h1-3,6-15,24,30H,4-5,16-18H2/b30-26?,32-27+
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241n/an/an/an/an/an/an/an/a



The United States of America, as represented by the Secretary, Department of Health and Human Services

US Patent


Assay Description
Measuring its tissue levels 1 hour after administration of 10 mg/kg to mice, plasma levels were comparable after oral or i.p. administration (indicat...


US Patent US10787419 (2020)

More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Mus musculus (Mouse))
BDBM463826
PNG
(US10787419, Serial # 35)
Show SMILES Clc1ccc(cc1)C1=NN(CC1c1ccccc1)C(=N\S(=O)(=O)c1ccc(Cl)cc1)\C(=N)N(CC=C)CC=C
Show InChI InChI=1S/C29H27Cl2N5O2S/c1-3-18-35(19-4-2)28(32)29(34-39(37,38)25-16-14-24(31)15-17-25)36-20-26(21-8-6-5-7-9-21)27(33-36)22-10-12-23(30)13-11-22/h3-17,26,32H,1-2,18-20H2/b32-28?,34-29+
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263n/an/an/an/an/an/an/an/a



The United States of America, as represented by the Secretary, Department of Health and Human Services

US Patent


Assay Description
Measuring its tissue levels 1 hour after administration of 10 mg/kg to mice, plasma levels were comparable after oral or i.p. administration (indicat...


US Patent US10787419 (2020)

More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Mus musculus (Mouse))
BDBM463852
PNG
(US10787419, Serial # 53)
Show SMILES Clc1ccc(cc1)C1=NN(CC1c1ccccc1)C(=N\S(=O)(=O)c1ccc(Cl)cc1)\C(=N)N1CCCCC1
Show InChI InChI=1S/C28H27Cl2N5O2S/c29-22-11-9-21(10-12-22)26-25(20-7-3-1-4-8-20)19-35(32-26)28(27(31)34-17-5-2-6-18-34)33-38(36,37)24-15-13-23(30)14-16-24/h1,3-4,7-16,25,31H,2,5-6,17-19H2/b31-27?,33-28+
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276n/an/an/an/an/an/an/an/a



The United States of America, as represented by the Secretary, Department of Health and Human Services

US Patent


Assay Description
Measuring its tissue levels 1 hour after administration of 10 mg/kg to mice, plasma levels were comparable after oral or i.p. administration (indicat...


US Patent US10787419 (2020)

More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Mus musculus (Mouse))
BDBM463813
PNG
(US10787419, Serial # 25)
Show SMILES Clc1ccc(cc1)C1=NN(CC1c1ccccc1)C(=N\S(=O)(=O)c1ccc(Cl)cc1)\C(=N)SCCc1ccccc1
Show InChI InChI=1S/C31H26Cl2N4O2S2/c32-25-13-11-24(12-14-25)29-28(23-9-5-2-6-10-23)21-37(35-29)31(30(34)40-20-19-22-7-3-1-4-8-22)36-41(38,39)27-17-15-26(33)16-18-27/h1-18,28,34H,19-21H2/b34-30?,36-31+
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287n/an/an/an/an/an/an/an/a



The United States of America, as represented by the Secretary, Department of Health and Human Services

US Patent


Assay Description
Measuring its tissue levels 1 hour after administration of 10 mg/kg to mice, plasma levels were comparable after oral or i.p. administration (indicat...


US Patent US10787419 (2020)

More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Mus musculus (Mouse))
BDBM463853
PNG
(US10787419, Serial # 54)
Show SMILES CN1CCN(CC1)C(=N)C(=N/S(=O)(=O)c1ccc(Cl)cc1)\N1CC(C(=N1)c1ccc(Cl)cc1)c1ccccc1
Show InChI InChI=1S/C28H28Cl2N6O2S/c1-34-15-17-35(18-16-34)27(31)28(33-39(37,38)24-13-11-23(30)12-14-24)36-19-25(20-5-3-2-4-6-20)26(32-36)21-7-9-22(29)10-8-21/h2-14,25,31H,15-19H2,1H3/b31-27?,33-28+
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309n/an/an/an/an/an/an/an/a



The United States of America, as represented by the Secretary, Department of Health and Human Services

US Patent


Assay Description
Measuring its tissue levels 1 hour after administration of 10 mg/kg to mice, plasma levels were comparable after oral or i.p. administration (indicat...


US Patent US10787419 (2020)

More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Mus musculus (Mouse))
BDBM463838
PNG
(US10787419, Serial # 45)
Show SMILES CNC(=N)C(=N/S(=O)(=O)c1ccc(Cl)cc1)\N1CC(C(=N1)c1ccc(Cl)cc1)c1ccccc1
Show InChI InChI=1S/C24H21Cl2N5O2S/c1-28-23(27)24(30-34(32,33)20-13-11-19(26)12-14-20)31-15-21(16-5-3-2-4-6-16)22(29-31)17-7-9-18(25)10-8-17/h2-14,21H,15H2,1H3,(H2,27,28)/b30-24+
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327n/an/an/an/an/an/an/an/a



The United States of America, as represented by the Secretary, Department of Health and Human Services

US Patent


Assay Description
Measuring its tissue levels 1 hour after administration of 10 mg/kg to mice, plasma levels were comparable after oral or i.p. administration (indicat...


US Patent US10787419 (2020)

More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Mus musculus (Mouse))
BDBM463848
PNG
(US10787419, Serial # 49)
Show SMILES CN(Cc1ccccc1)C(=N)C(=N/S(=O)(=O)c1ccc(Cl)cc1)\N1CC(C(=N1)c1ccc(Cl)cc1)c1ccccc1
Show InChI InChI=1S/C31H27Cl2N5O2S/c1-37(20-22-8-4-2-5-9-22)30(34)31(36-41(39,40)27-18-16-26(33)17-19-27)38-21-28(23-10-6-3-7-11-23)29(35-38)24-12-14-25(32)15-13-24/h2-19,28,34H,20-21H2,1H3/b34-30?,36-31+
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343n/an/an/an/an/an/an/an/a



The United States of America, as represented by the Secretary, Department of Health and Human Services

US Patent


Assay Description
Measuring its tissue levels 1 hour after administration of 10 mg/kg to mice, plasma levels were comparable after oral or i.p. administration (indicat...


US Patent US10787419 (2020)

More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Mus musculus (Mouse))
BDBM463858
PNG
(US10787419, Serial # 59)
Show SMILES CC(C)(C)OC(=O)N1CCN(CC1)C(=N)C(=N/S(=O)(=O)c1ccc(Cl)cc1)\N1CC(C(=N1)c1ccc(Cl)cc1)c1ccccc1
Show InChI InChI=1S/C32H34Cl2N6O4S/c1-32(2,3)44-31(41)39-19-17-38(18-20-39)29(35)30(37-45(42,43)26-15-13-25(34)14-16-26)40-21-27(22-7-5-4-6-8-22)28(36-40)23-9-11-24(33)12-10-23/h4-16,27,35H,17-21H2,1-3H3/b35-29?,37-30+
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387n/an/an/an/an/an/an/an/a



The United States of America, as represented by the Secretary, Department of Health and Human Services

US Patent


Assay Description
Measuring its tissue levels 1 hour after administration of 10 mg/kg to mice, plasma levels were comparable after oral or i.p. administration (indicat...


US Patent US10787419 (2020)

More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Mus musculus (Mouse))
BDBM463775
PNG
(US10787419, Serial # 1)
Show SMILES Clc1ccc(cc1)C1=NN(CC1c1ccccc1)C(\C=N)=N\S(=O)(=O)c1ccc(Cl)cc1
Show InChI InChI=1S/C23H18Cl2N4O2S/c24-18-8-6-17(7-9-18)23-21(16-4-2-1-3-5-16)15-29(27-23)22(14-26)28-32(30,31)20-12-10-19(25)11-13-20/h1-14,21,26H,15H2/b26-14?,28-22+
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392n/an/an/an/an/an/an/an/a



The United States of America, as represented by the Secretary, Department of Health and Human Services

US Patent


Assay Description
Measuring its tissue levels 1 hour after administration of 10 mg/kg to mice, plasma levels were comparable after oral or i.p. administration (indicat...


US Patent US10787419 (2020)

More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Mus musculus (Mouse))
BDBM463856
PNG
(US10787419, Serial # 57)
Show SMILES Clc1ccc(cc1)C1=NN(CC1c1ccccc1)C(=N\S(=O)(=O)c1ccc(Cl)cc1)\C(=N)NC1CCCCC1
Show InChI InChI=1S/C29H29Cl2N5O2S/c30-22-13-11-21(12-14-22)27-26(20-7-3-1-4-8-20)19-36(34-27)29(28(32)33-24-9-5-2-6-10-24)35-39(37,38)25-17-15-23(31)16-18-25/h1,3-4,7-8,11-18,24,26H,2,5-6,9-10,19H2,(H2,32,33)/b35-29+
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419n/an/an/an/an/an/an/an/a



The United States of America, as represented by the Secretary, Department of Health and Human Services

US Patent


Assay Description
Measuring its tissue levels 1 hour after administration of 10 mg/kg to mice, plasma levels were comparable after oral or i.p. administration (indicat...


US Patent US10787419 (2020)

More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Mus musculus (Mouse))
BDBM463830
PNG
(US10787419, Serial # 39)
Show SMILES COCCN(CCOC)C(=N)C(=N/S(=O)(=O)c1ccc(Cl)cc1)\N1CC(C(=N1)c1ccc(Cl)cc1)c1ccccc1
Show InChI InChI=1S/C29H31Cl2N5O4S/c1-39-18-16-35(17-19-40-2)28(32)29(34-41(37,38)25-14-12-24(31)13-15-25)36-20-26(21-6-4-3-5-7-21)27(33-36)22-8-10-23(30)11-9-22/h3-15,26,32H,16-20H2,1-2H3/b32-28?,34-29+
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425n/an/an/an/an/an/an/an/a



The United States of America, as represented by the Secretary, Department of Health and Human Services

US Patent


Assay Description
Measuring its tissue levels 1 hour after administration of 10 mg/kg to mice, plasma levels were comparable after oral or i.p. administration (indicat...


US Patent US10787419 (2020)

More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Mus musculus (Mouse))
BDBM463868
PNG
(US10787419, Serial # 68)
Show SMILES COC(CN(C)C(=N)C(=N/S(=O)(=O)c1ccc(Cl)cc1)\N1CC(C(=N1)c1ccc(Cl)cc1)c1ccccc1)OC
Show InChI InChI=1S/C28H29Cl2N5O4S/c1-34(18-25(38-2)39-3)27(31)28(33-40(36,37)23-15-13-22(30)14-16-23)35-17-24(19-7-5-4-6-8-19)26(32-35)20-9-11-21(29)12-10-20/h4-16,24-25,31H,17-18H2,1-3H3/b31-27?,33-28+
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443n/an/an/an/an/an/an/an/a



The United States of America, as represented by the Secretary, Department of Health and Human Services

US Patent


Assay Description
Measuring its tissue levels 1 hour after administration of 10 mg/kg to mice, plasma levels were comparable after oral or i.p. administration (indicat...


US Patent US10787419 (2020)

More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Mus musculus (Mouse))
BDBM463859
PNG
(US10787419, Serial # 60)
Show SMILES COC(CNC(=N)C(=N/S(=O)(=O)c1ccc(Cl)cc1)\N1CC(C(=N1)c1ccc(Cl)cc1)c1ccccc1)OC
Show InChI InChI=1S/C27H27Cl2N5O4S/c1-37-24(38-2)16-31-26(30)27(33-39(35,36)22-14-12-21(29)13-15-22)34-17-23(18-6-4-3-5-7-18)25(32-34)19-8-10-20(28)11-9-19/h3-15,23-24H,16-17H2,1-2H3,(H2,30,31)/b33-27+
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443n/an/an/an/an/an/an/an/a



The United States of America, as represented by the Secretary, Department of Health and Human Services

US Patent


Assay Description
Measuring its tissue levels 1 hour after administration of 10 mg/kg to mice, plasma levels were comparable after oral or i.p. administration (indicat...


US Patent US10787419 (2020)

More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Mus musculus (Mouse))
BDBM463855
PNG
(US10787419, Serial # 56)
Show SMILES Clc1ccc(cc1)C1=NN(CC1c1ccccc1)C(=N\S(=O)(=O)c1ccc(Cl)cc1)\C(=N)NC1CCCC1
Show InChI InChI=1S/C28H27Cl2N5O2S/c29-21-12-10-20(11-13-21)26-25(19-6-2-1-3-7-19)18-35(33-26)28(27(31)32-23-8-4-5-9-23)34-38(36,37)24-16-14-22(30)15-17-24/h1-3,6-7,10-17,23,25H,4-5,8-9,18H2,(H2,31,32)/b34-28+
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459n/an/an/an/an/an/an/an/a



The United States of America, as represented by the Secretary, Department of Health and Human Services

US Patent


Assay Description
Measuring its tissue levels 1 hour after administration of 10 mg/kg to mice, plasma levels were comparable after oral or i.p. administration (indicat...


US Patent US10787419 (2020)

More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Mus musculus (Mouse))
BDBM463849
PNG
(US10787419, Serial # 50)
Show SMILES Clc1ccc(cc1)C1=NN(CC1c1ccccc1)C(=N\S(=O)(=O)c1ccc(Cl)cc1)\C(=N)NCc1ccccc1
Show InChI InChI=1S/C30H25Cl2N5O2S/c31-24-13-11-23(12-14-24)28-27(22-9-5-2-6-10-22)20-37(35-28)30(29(33)34-19-21-7-3-1-4-8-21)36-40(38,39)26-17-15-25(32)16-18-26/h1-18,27H,19-20H2,(H2,33,34)/b36-30+
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505n/an/an/an/an/an/an/an/a



The United States of America, as represented by the Secretary, Department of Health and Human Services

US Patent


Assay Description
Measuring its tissue levels 1 hour after administration of 10 mg/kg to mice, plasma levels were comparable after oral or i.p. administration (indicat...


US Patent US10787419 (2020)

More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Mus musculus (Mouse))
BDBM463845
PNG
(US10787419, Serial # 47)
Show SMILES CC(C)NC(=N)C(=N/S(=O)(=O)c1ccc(Cl)cc1)\N1CC(C(=N1)c1ccc(Cl)cc1)c1ccccc1
Show InChI InChI=1S/C26H25Cl2N5O2S/c1-17(2)30-25(29)26(32-36(34,35)22-14-12-21(28)13-15-22)33-16-23(18-6-4-3-5-7-18)24(31-33)19-8-10-20(27)11-9-19/h3-15,17,23H,16H2,1-2H3,(H2,29,30)/b32-26+
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516n/an/an/an/an/an/an/an/a



The United States of America, as represented by the Secretary, Department of Health and Human Services

US Patent


Assay Description
Measuring its tissue levels 1 hour after administration of 10 mg/kg to mice, plasma levels were comparable after oral or i.p. administration (indicat...


US Patent US10787419 (2020)

More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Mus musculus (Mouse))
BDBM463794
PNG
(US10787419, Serial # 10E2)
Show SMILES Fc1ccc(cc1)C(=N)C(=N/S(=O)(=O)c1ccc(Cl)cc1)\N1C[C@H](C(=N1)c1ccc(Cl)cc1)c1ccccc1
Show InChI InChI=1S/C29H21Cl2FN4O2S/c30-22-10-6-21(7-11-22)28-26(19-4-2-1-3-5-19)18-36(34-28)29(27(33)20-8-14-24(32)15-9-20)35-39(37,38)25-16-12-23(31)13-17-25/h1-17,26,33H,18H2/b33-27?,35-29+/t26-/m0/s1
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524n/an/an/an/an/an/an/an/a



The United States of America, as represented by the Secretary, Department of Health and Human Services

US Patent


Assay Description
Measuring its tissue levels 1 hour after administration of 10 mg/kg to mice, plasma levels were comparable after oral or i.p. administration (indicat...


US Patent US10787419 (2020)

More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Mus musculus (Mouse))
BDBM463827
PNG
(US10787419, Serial # 36)
Show SMILES CCCCN(CC)C(=N)C(=N/S(=O)(=O)c1ccc(Cl)cc1)\N1CC(C(=N1)c1ccc(Cl)cc1)c1ccccc1
Show InChI InChI=1S/C29H31Cl2N5O2S/c1-3-5-19-35(4-2)28(32)29(34-39(37,38)25-17-15-24(31)16-18-25)36-20-26(21-9-7-6-8-10-21)27(33-36)22-11-13-23(30)14-12-22/h6-18,26,32H,3-5,19-20H2,1-2H3/b32-28?,34-29+
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535n/an/an/an/an/an/an/an/a



The United States of America, as represented by the Secretary, Department of Health and Human Services

US Patent


Assay Description
Measuring its tissue levels 1 hour after administration of 10 mg/kg to mice, plasma levels were comparable after oral or i.p. administration (indicat...


US Patent US10787419 (2020)

More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Mus musculus (Mouse))
BDBM463857
PNG
(US10787419, Serial # 58)
Show SMILES Clc1ccc(cc1)C1=NN(CC1c1ccccc1)C(=N\S(=O)(=O)c1ccc(Cl)cc1)\C(=N)NCCc1c[nH]c2ccccc12
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585n/an/an/an/an/an/an/an/a



The United States of America, as represented by the Secretary, Department of Health and Human Services

US Patent


Assay Description
Measuring its tissue levels 1 hour after administration of 10 mg/kg to mice, plasma levels were comparable after oral or i.p. administration (indicat...


US Patent US10787419 (2020)

More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Mus musculus (Mouse))
BDBM463831
PNG
(US10787419, Serial # 40)
Show SMILES COCCNC(=N)C(=N/S(=O)(=O)c1ccc(Cl)cc1)\N1CC(C(=N1)c1ccc(Cl)cc1)c1ccccc1
Show InChI InChI=1S/C26H25Cl2N5O3S/c1-36-16-15-30-25(29)26(32-37(34,35)22-13-11-21(28)12-14-22)33-17-23(18-5-3-2-4-6-18)24(31-33)19-7-9-20(27)10-8-19/h2-14,23H,15-17H2,1H3,(H2,29,30)/b32-26+
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848n/an/an/an/an/an/an/an/a



The United States of America, as represented by the Secretary, Department of Health and Human Services

US Patent


Assay Description
Measuring its tissue levels 1 hour after administration of 10 mg/kg to mice, plasma levels were comparable after oral or i.p. administration (indicat...


US Patent US10787419 (2020)

More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Mus musculus (Mouse))
BDBM463833
PNG
(US10787419, Serial # 42 | US10787419, Serial # 43)
Show SMILES COCCN(C)C(=N)C(=N/S(=O)(=O)c1ccc(Cl)cc1)\N1CC(C(=N1)c1ccc(Cl)cc1)c1ccccc1
Show InChI InChI=1S/C27H27Cl2N5O3S/c1-33(16-17-37-2)26(30)27(32-38(35,36)23-14-12-22(29)13-15-23)34-18-24(19-6-4-3-5-7-19)25(31-34)20-8-10-21(28)11-9-20/h3-15,24,30H,16-18H2,1-2H3/b30-26?,32-27+
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908n/an/an/an/an/an/an/an/a



The United States of America, as represented by the Secretary, Department of Health and Human Services

US Patent


Assay Description
Measuring its tissue levels 1 hour after administration of 10 mg/kg to mice, plasma levels were comparable after oral or i.p. administration (indicat...


US Patent US10787419 (2020)

More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Mus musculus (Mouse))
BDBM463850
PNG
(US10787419, Serial # 51)
Show SMILES Clc1ccc(cc1)C1=NN(CC1c1ccccc1)C(=N\S(=O)(=O)c1ccc(Cl)cc1)\C(=N)NCCc1ccccc1
Show InChI InChI=1S/C31H27Cl2N5O2S/c32-25-13-11-24(12-14-25)29-28(23-9-5-2-6-10-23)21-38(36-29)31(30(34)35-20-19-22-7-3-1-4-8-22)37-41(39,40)27-17-15-26(33)16-18-27/h1-18,28H,19-21H2,(H2,34,35)/b37-31+
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931n/an/an/an/an/an/an/an/a



The United States of America, as represented by the Secretary, Department of Health and Human Services

US Patent


Assay Description
Measuring its tissue levels 1 hour after administration of 10 mg/kg to mice, plasma levels were comparable after oral or i.p. administration (indicat...


US Patent US10787419 (2020)

More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Mus musculus (Mouse))
BDBM463797
PNG
(US10787419, Serial # 11E2)
Show SMILES Clc1ccc(cc1)C(=N)C(=N/S(=O)(=O)c1ccc(Cl)cc1)\N1C[C@H](C(=N1)c1ccc(Cl)cc1)c1ccccc1
Show InChI InChI=1S/C29H21Cl3N4O2S/c30-22-10-6-20(7-11-22)27(33)29(35-39(37,38)25-16-14-24(32)15-17-25)36-18-26(19-4-2-1-3-5-19)28(34-36)21-8-12-23(31)13-9-21/h1-17,26,33H,18H2/b33-27?,35-29+/t26-/m0/s1
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>1.00E+3n/an/an/an/an/an/an/an/a



The United States of America, as represented by the Secretary, Department of Health and Human Services

US Patent


Assay Description
Measuring its tissue levels 1 hour after administration of 10 mg/kg to mice, plasma levels were comparable after oral or i.p. administration (indicat...


US Patent US10787419 (2020)

More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Mus musculus (Mouse))
BDBM463861
PNG
(US10787419, Serial # 62)
Show SMILES CN(CC12CC3CC(CC(C3)C1)C2)C(=N)C(=N/S(=O)(=O)c1ccc(Cl)cc1)\N1CC(C(=N1)c1ccc(Cl)cc1)c1ccccc1
Show InChI InChI=1S/C35H37Cl2N5O2S/c1-41(22-35-18-23-15-24(19-35)17-25(16-23)20-35)33(38)34(40-45(43,44)30-13-11-29(37)12-14-30)42-21-31(26-5-3-2-4-6-26)32(39-42)27-7-9-28(36)10-8-27/h2-14,23-25,31,38H,15-22H2,1H3/b38-33?,40-34+
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>1.00E+3n/an/an/an/an/an/an/an/a



The United States of America, as represented by the Secretary, Department of Health and Human Services

US Patent


Assay Description
Measuring its tissue levels 1 hour after administration of 10 mg/kg to mice, plasma levels were comparable after oral or i.p. administration (indicat...


US Patent US10787419 (2020)

More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Mus musculus (Mouse))
BDBM463863
PNG
(US10787419, Serial # 64)
Show SMILES Clc1ccc(cc1)C1=NN(CC1c1ccccc1)C(=N\S(=O)(=O)c1ccc(Cl)cc1)\C(=N)NC12CC3CC(CC(C3)C1)C2
Show InChI InChI=1S/C33H33Cl2N5O2S/c34-26-8-6-25(7-9-26)30-29(24-4-2-1-3-5-24)20-40(38-30)32(39-43(41,42)28-12-10-27(35)11-13-28)31(36)37-33-17-21-14-22(18-33)16-23(15-21)19-33/h1-13,21-23,29H,14-20H2,(H2,36,37)/b39-32+
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>1.00E+3n/an/an/an/an/an/an/an/a



The United States of America, as represented by the Secretary, Department of Health and Human Services

US Patent


Assay Description
Measuring its tissue levels 1 hour after administration of 10 mg/kg to mice, plasma levels were comparable after oral or i.p. administration (indicat...


US Patent US10787419 (2020)

More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Mus musculus (Mouse))
BDBM463867
PNG
(US10787419, Serial # 67)
Show SMILES CN(CC(C)(C)C)C(=N)C(=N/S(=O)(=O)c1ccc(Cl)cc1)\N1CC(C(=N1)c1ccc(Cl)cc1)c1ccccc1
Show InChI InChI=1S/C29H31Cl2N5O2S/c1-29(2,3)19-35(4)27(32)28(34-39(37,38)24-16-14-23(31)15-17-24)36-18-25(20-8-6-5-7-9-20)26(33-36)21-10-12-22(30)13-11-21/h5-17,25,32H,18-19H2,1-4H3/b32-27?,34-28+
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2.39E+3n/an/an/an/an/an/an/an/a



The United States of America, as represented by the Secretary, Department of Health and Human Services

US Patent


Assay Description
Measuring its tissue levels 1 hour after administration of 10 mg/kg to mice, plasma levels were comparable after oral or i.p. administration (indicat...


US Patent US10787419 (2020)

More data for this
Ligand-Target Pair
* indicates data uncertainty>20%