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Patent code US10787425

Compile Data Set for Download or QSAR
Found 105 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
15-hydroxyprostaglandin dehydrogenase [NAD+]


(Homo sapiens (Human))
BDBM463902
PNG
(US10787425, Compound 29)
Show SMILES Brc1cc(\C=C2/SC(=O)NC2=O)ccc1OC(=O)CCCc1ccccc1
Show InChI InChI=1S/C20H16BrNO4S/c21-15-11-14(12-17-19(24)22-20(25)27-17)9-10-16(15)26-18(23)8-4-7-13-5-2-1-3-6-13/h1-3,5-6,9-12H,4,7-8H2,(H,22,24,25)/b17-12-
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n/an/a 14.5n/an/an/an/an/an/a



INDUSTRY-ACADEMIC COOPERATION FOUNDATION CHOSUN UNIVERSITY

US Patent


Assay Description
To confirm whether the compounds according to the present disclosure have an effect of inhibiting 15-PGDH, the NADH, which appears at the wavelength ...


US Patent US10787425 (2020)

More data for this
Ligand-Target Pair
15-hydroxyprostaglandin dehydrogenase [NAD+]


(Homo sapiens (Human))
BDBM463881
PNG
(US10787425, Compound 8)
Show SMILES Clc1cc(\C=C2/SC(=O)NC2=O)ccc1OC(=O)CCC1CCCCC1
Show InChI InChI=1S/C19H20ClNO4S/c20-14-10-13(11-16-18(23)21-19(24)26-16)6-8-15(14)25-17(22)9-7-12-4-2-1-3-5-12/h6,8,10-12H,1-5,7,9H2,(H,21,23,24)/b16-11-
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n/an/a 15.3n/an/an/an/an/an/a



INDUSTRY-ACADEMIC COOPERATION FOUNDATION CHOSUN UNIVERSITY

US Patent


Assay Description
To confirm whether the compounds according to the present disclosure have an effect of inhibiting 15-PGDH, the NADH, which appears at the wavelength ...


US Patent US10787425 (2020)

More data for this
Ligand-Target Pair
15-hydroxyprostaglandin dehydrogenase [NAD+]


(Homo sapiens (Human))
BDBM463897
PNG
(US10787425, Compound 24)
Show SMILES Brc1cc(\C=C2/SC(=O)NC2=O)ccc1OC(=O)CCCC1CCCCC1
Show InChI InChI=1S/C20H22BrNO4S/c21-15-11-14(12-17-19(24)22-20(25)27-17)9-10-16(15)26-18(23)8-4-7-13-5-2-1-3-6-13/h9-13H,1-8H2,(H,22,24,25)/b17-12-
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n/an/a 15.4n/an/an/an/an/an/a



INDUSTRY-ACADEMIC COOPERATION FOUNDATION CHOSUN UNIVERSITY

US Patent


Assay Description
To confirm whether the compounds according to the present disclosure have an effect of inhibiting 15-PGDH, the NADH, which appears at the wavelength ...


US Patent US10787425 (2020)

More data for this
Ligand-Target Pair
15-hydroxyprostaglandin dehydrogenase [NAD+]


(Homo sapiens (Human))
BDBM463893
PNG
(US10787425, Compound 20)
Show SMILES Brc1cc(\C=C2/SC(=O)NC2=O)ccc1OC(=O)CCC1CCCC1
Show InChI InChI=1S/C18H18BrNO4S/c19-13-9-12(10-15-17(22)20-18(23)25-15)5-7-14(13)24-16(21)8-6-11-3-1-2-4-11/h5,7,9-11H,1-4,6,8H2,(H,20,22,23)/b15-10-
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n/an/a 15.8n/an/an/an/an/an/a



INDUSTRY-ACADEMIC COOPERATION FOUNDATION CHOSUN UNIVERSITY

US Patent


Assay Description
To confirm whether the compounds according to the present disclosure have an effect of inhibiting 15-PGDH, the NADH, which appears at the wavelength ...


US Patent US10787425 (2020)

More data for this
Ligand-Target Pair
15-hydroxyprostaglandin dehydrogenase [NAD+]


(Homo sapiens (Human))
BDBM463896
PNG
(US10787425, Compound 23)
Show SMILES Brc1cc(\C=C2/SC(=O)NC2=O)ccc1OC(=O)CCC1CCCCC1
Show InChI InChI=1S/C19H20BrNO4S/c20-14-10-13(11-16-18(23)21-19(24)26-16)6-8-15(14)25-17(22)9-7-12-4-2-1-3-5-12/h6,8,10-12H,1-5,7,9H2,(H,21,23,24)/b16-11-
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n/an/a 16.6n/an/an/an/an/an/a



INDUSTRY-ACADEMIC COOPERATION FOUNDATION CHOSUN UNIVERSITY

US Patent


Assay Description
To confirm whether the compounds according to the present disclosure have an effect of inhibiting 15-PGDH, the NADH, which appears at the wavelength ...


US Patent US10787425 (2020)

More data for this
Ligand-Target Pair
15-hydroxyprostaglandin dehydrogenase [NAD+]


(Homo sapiens (Human))
BDBM463911
PNG
(US10787425, Compound 38)
Show SMILES COc1cc(\C=C2/SC(=O)NC2=O)ccc1OC(=O)CCC1CCCCC1
Show InChI InChI=1S/C20H23NO5S/c1-25-16-11-14(12-17-19(23)21-20(24)27-17)7-9-15(16)26-18(22)10-8-13-5-3-2-4-6-13/h7,9,11-13H,2-6,8,10H2,1H3,(H,21,23,24)/b17-12-
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n/an/a 17.3n/an/an/an/an/an/a



INDUSTRY-ACADEMIC COOPERATION FOUNDATION CHOSUN UNIVERSITY

US Patent


Assay Description
To confirm whether the compounds according to the present disclosure have an effect of inhibiting 15-PGDH, the NADH, which appears at the wavelength ...


US Patent US10787425 (2020)

More data for this
Ligand-Target Pair
15-hydroxyprostaglandin dehydrogenase [NAD+]


(Homo sapiens (Human))
BDBM463912
PNG
(US10787425, Compound 39)
Show SMILES COc1cc(\C=C2/SC(=O)NC2=O)ccc1OC(=O)CCCC1CCCCC1
Show InChI InChI=1S/C21H25NO5S/c1-26-17-12-15(13-18-20(24)22-21(25)28-18)10-11-16(17)27-19(23)9-5-8-14-6-3-2-4-7-14/h10-14H,2-9H2,1H3,(H,22,24,25)/b18-13-
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n/an/a 17.5n/an/an/an/an/an/a



INDUSTRY-ACADEMIC COOPERATION FOUNDATION CHOSUN UNIVERSITY

US Patent


Assay Description
To confirm whether the compounds according to the present disclosure have an effect of inhibiting 15-PGDH, the NADH, which appears at the wavelength ...


US Patent US10787425 (2020)

More data for this
Ligand-Target Pair
15-hydroxyprostaglandin dehydrogenase [NAD+]


(Homo sapiens (Human))
BDBM463942
PNG
(US10787425, Compound 68)
Show SMILES O=C(CCC1CCCCC1)Oc1ccc(\C=C2/SC(=O)NC2=O)cc1
Show InChI InChI=1S/C19H21NO4S/c21-17(11-8-13-4-2-1-3-5-13)24-15-9-6-14(7-10-15)12-16-18(22)20-19(23)25-16/h6-7,9-10,12-13H,1-5,8,11H2,(H,20,22,23)/b16-12-
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n/an/a 18.4n/an/an/an/an/an/a



INDUSTRY-ACADEMIC COOPERATION FOUNDATION CHOSUN UNIVERSITY

US Patent


Assay Description
To confirm whether the compounds according to the present disclosure have an effect of inhibiting 15-PGDH, the NADH, which appears at the wavelength ...


US Patent US10787425 (2020)

More data for this
Ligand-Target Pair
15-hydroxyprostaglandin dehydrogenase [NAD+]


(Homo sapiens (Human))
BDBM463892
PNG
(US10787425, Compound 19)
Show SMILES Brc1cc(\C=C2/SC(=O)NC2=O)ccc1OC(=O)CC1CCCC1
Show InChI InChI=1S/C17H16BrNO4S/c18-12-7-11(8-14-16(21)19-17(22)24-14)5-6-13(12)23-15(20)9-10-3-1-2-4-10/h5-8,10H,1-4,9H2,(H,19,21,22)/b14-8-
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n/an/a 19.8n/an/an/an/an/an/a



INDUSTRY-ACADEMIC COOPERATION FOUNDATION CHOSUN UNIVERSITY

US Patent


Assay Description
To confirm whether the compounds according to the present disclosure have an effect of inhibiting 15-PGDH, the NADH, which appears at the wavelength ...


US Patent US10787425 (2020)

More data for this
Ligand-Target Pair
15-hydroxyprostaglandin dehydrogenase [NAD+]


(Homo sapiens (Human))
BDBM463882
PNG
(US10787425, Compound 9)
Show SMILES Clc1cc(\C=C2/SC(=O)NC2=O)ccc1CC(=O)OCCC1CCCCC1
Show InChI InChI=1S/C20H22ClNO4S/c21-16-10-14(11-17-19(24)22-20(25)27-17)6-7-15(16)12-18(23)26-9-8-13-4-2-1-3-5-13/h6-7,10-11,13H,1-5,8-9,12H2,(H,22,24,25)/b17-11-
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n/an/a 20.2n/an/an/an/an/an/a



INDUSTRY-ACADEMIC COOPERATION FOUNDATION CHOSUN UNIVERSITY

US Patent


Assay Description
To confirm whether the compounds according to the present disclosure have an effect of inhibiting 15-PGDH, the NADH, which appears at the wavelength ...


US Patent US10787425 (2020)

More data for this
Ligand-Target Pair
15-hydroxyprostaglandin dehydrogenase [NAD+]


(Homo sapiens (Human))
BDBM463895
PNG
(US10787425, Compound 22)
Show SMILES Brc1cc(\C=C2/SC(=O)NC2=O)ccc1OC(=O)CC1CCCCC1
Show InChI InChI=1S/C18H18BrNO4S/c19-13-8-12(9-15-17(22)20-18(23)25-15)6-7-14(13)24-16(21)10-11-4-2-1-3-5-11/h6-9,11H,1-5,10H2,(H,20,22,23)/b15-9-
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n/an/a 20.6n/an/an/an/an/an/a



INDUSTRY-ACADEMIC COOPERATION FOUNDATION CHOSUN UNIVERSITY

US Patent


Assay Description
To confirm whether the compounds according to the present disclosure have an effect of inhibiting 15-PGDH, the NADH, which appears at the wavelength ...


US Patent US10787425 (2020)

More data for this
Ligand-Target Pair
15-hydroxyprostaglandin dehydrogenase [NAD+]


(Homo sapiens (Human))
BDBM463887
PNG
(US10787425, Compound 14)
Show SMILES Clc1cc(\C=C2/SC(=O)NC2=O)ccc1OC(=O)CCCc1ccccc1
Show InChI InChI=1S/C20H16ClNO4S/c21-15-11-14(12-17-19(24)22-20(25)27-17)9-10-16(15)26-18(23)8-4-7-13-5-2-1-3-6-13/h1-3,5-6,9-12H,4,7-8H2,(H,22,24,25)/b17-12-
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n/an/a 22n/an/an/an/an/an/a



INDUSTRY-ACADEMIC COOPERATION FOUNDATION CHOSUN UNIVERSITY

US Patent


Assay Description
To confirm whether the compounds according to the present disclosure have an effect of inhibiting 15-PGDH, the NADH, which appears at the wavelength ...


US Patent US10787425 (2020)

More data for this
Ligand-Target Pair
15-hydroxyprostaglandin dehydrogenase [NAD+]


(Homo sapiens (Human))
BDBM463962
PNG
(US10787425, Compound 88)
Show SMILES Clc1c(OC(=O)CCc2ccccc2)cccc1\C=C1/SC(=O)NC1=O
Show InChI InChI=1S/C19H14ClNO4S/c20-17-13(11-15-18(23)21-19(24)26-15)7-4-8-14(17)25-16(22)10-9-12-5-2-1-3-6-12/h1-8,11H,9-10H2,(H,21,23,24)/b15-11-
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n/an/a 22.5n/an/an/an/an/an/a



INDUSTRY-ACADEMIC COOPERATION FOUNDATION CHOSUN UNIVERSITY

US Patent


Assay Description
To confirm whether the compounds according to the present disclosure have an effect of inhibiting 15-PGDH, the NADH, which appears at the wavelength ...


US Patent US10787425 (2020)

More data for this
Ligand-Target Pair
15-hydroxyprostaglandin dehydrogenase [NAD+]


(Homo sapiens (Human))
BDBM463958
PNG
(US10787425, Compound 84)
Show SMILES Clc1c(OC(=O)CCCC2CCCCC2)cccc1\C=C1/SC(=O)NC1=O
Show InChI InChI=1S/C20H22ClNO4S/c21-18-14(12-16-19(24)22-20(25)27-16)9-5-10-15(18)26-17(23)11-4-8-13-6-2-1-3-7-13/h5,9-10,12-13H,1-4,6-8,11H2,(H,22,24,25)/b16-12-
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n/an/a 22.5n/an/an/an/an/an/a



INDUSTRY-ACADEMIC COOPERATION FOUNDATION CHOSUN UNIVERSITY

US Patent


Assay Description
To confirm whether the compounds according to the present disclosure have an effect of inhibiting 15-PGDH, the NADH, which appears at the wavelength ...


US Patent US10787425 (2020)

More data for this
Ligand-Target Pair
15-hydroxyprostaglandin dehydrogenase [NAD+]


(Homo sapiens (Human))
BDBM463957
PNG
(US10787425, Compound 83)
Show SMILES Clc1c(OC(=O)CCC2CCCCC2)cccc1\C=C1/SC(=O)NC1=O
Show InChI InChI=1S/C19H20ClNO4S/c20-17-13(11-15-18(23)21-19(24)26-15)7-4-8-14(17)25-16(22)10-9-12-5-2-1-3-6-12/h4,7-8,11-12H,1-3,5-6,9-10H2,(H,21,23,24)/b15-11-
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n/an/a 22.8n/an/an/an/an/an/a



INDUSTRY-ACADEMIC COOPERATION FOUNDATION CHOSUN UNIVERSITY

US Patent


Assay Description
To confirm whether the compounds according to the present disclosure have an effect of inhibiting 15-PGDH, the NADH, which appears at the wavelength ...


US Patent US10787425 (2020)

More data for this
Ligand-Target Pair
15-hydroxyprostaglandin dehydrogenase [NAD+]


(Homo sapiens (Human))
BDBM463939
PNG
(US10787425, Compound 65)
Show SMILES O=C(CCC1CCCC1)Oc1ccc(\C=C2/SC(=O)NC2=O)cc1
Show InChI InChI=1S/C18H19NO4S/c20-16(10-7-12-3-1-2-4-12)23-14-8-5-13(6-9-14)11-15-17(21)19-18(22)24-15/h5-6,8-9,11-12H,1-4,7,10H2,(H,19,21,22)/b15-11-
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n/an/a 23.2n/an/an/an/an/an/a



INDUSTRY-ACADEMIC COOPERATION FOUNDATION CHOSUN UNIVERSITY

US Patent


Assay Description
To confirm whether the compounds according to the present disclosure have an effect of inhibiting 15-PGDH, the NADH, which appears at the wavelength ...


US Patent US10787425 (2020)

More data for this
Ligand-Target Pair
15-hydroxyprostaglandin dehydrogenase [NAD+]


(Homo sapiens (Human))
BDBM463908
PNG
(US10787425, Compound 35)
Show SMILES COc1cc(\C=C2/SC(=O)NC2=O)ccc1OC(=O)CCC1CCCC1
Show InChI InChI=1S/C19H21NO5S/c1-24-15-10-13(11-16-18(22)20-19(23)26-16)6-8-14(15)25-17(21)9-7-12-4-2-3-5-12/h6,8,10-12H,2-5,7,9H2,1H3,(H,20,22,23)/b16-11-
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n/an/a 23.4n/an/an/an/an/an/a



INDUSTRY-ACADEMIC COOPERATION FOUNDATION CHOSUN UNIVERSITY

US Patent


Assay Description
To confirm whether the compounds according to the present disclosure have an effect of inhibiting 15-PGDH, the NADH, which appears at the wavelength ...


US Patent US10787425 (2020)

More data for this
Ligand-Target Pair
15-hydroxyprostaglandin dehydrogenase [NAD+]


(Homo sapiens (Human))
BDBM463903
PNG
(US10787425, Compound 30)
Show SMILES Brc1cc(\C=C2/SC(=O)NC2=O)ccc1OC(=O)CCCCc1ccccc1
Show InChI InChI=1S/C21H18BrNO4S/c22-16-12-15(13-18-20(25)23-21(26)28-18)10-11-17(16)27-19(24)9-5-4-8-14-6-2-1-3-7-14/h1-3,6-7,10-13H,4-5,8-9H2,(H,23,25,26)/b18-13-
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n/an/a 23.5n/an/an/an/an/an/a



INDUSTRY-ACADEMIC COOPERATION FOUNDATION CHOSUN UNIVERSITY

US Patent


Assay Description
To confirm whether the compounds according to the present disclosure have an effect of inhibiting 15-PGDH, the NADH, which appears at the wavelength ...


US Patent US10787425 (2020)

More data for this
Ligand-Target Pair
15-hydroxyprostaglandin dehydrogenase [NAD+]


(Homo sapiens (Human))
BDBM463928
PNG
(US10787425, Compound 54)
Show SMILES CCOc1cc(\C=C2/SC(=O)NC2=O)ccc1OC(=O)CCCC1CCCCC1
Show InChI InChI=1S/C22H27NO5S/c1-2-27-18-13-16(14-19-21(25)23-22(26)29-19)11-12-17(18)28-20(24)10-6-9-15-7-4-3-5-8-15/h11-15H,2-10H2,1H3,(H,23,25,26)/b19-14-
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n/an/a 23.8n/an/an/an/an/an/a



INDUSTRY-ACADEMIC COOPERATION FOUNDATION CHOSUN UNIVERSITY

US Patent


Assay Description
To confirm whether the compounds according to the present disclosure have an effect of inhibiting 15-PGDH, the NADH, which appears at the wavelength ...


US Patent US10787425 (2020)

More data for this
Ligand-Target Pair
15-hydroxyprostaglandin dehydrogenase [NAD+]


(Homo sapiens (Human))
BDBM463880
PNG
(US10787425, Compound 7)
Show SMILES Clc1cc(\C=C2/SC(=O)NC2=O)ccc1OC(=O)CC1CCCCC1
Show InChI InChI=1S/C18H18ClNO4S/c19-13-8-12(9-15-17(22)20-18(23)25-15)6-7-14(13)24-16(21)10-11-4-2-1-3-5-11/h6-9,11H,1-5,10H2,(H,20,22,23)/b15-9-
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n/an/a 23.8n/an/an/an/an/an/a



INDUSTRY-ACADEMIC COOPERATION FOUNDATION CHOSUN UNIVERSITY

US Patent


Assay Description
To confirm whether the compounds according to the present disclosure have an effect of inhibiting 15-PGDH, the NADH, which appears at the wavelength ...


US Patent US10787425 (2020)

More data for this
Ligand-Target Pair
15-hydroxyprostaglandin dehydrogenase [NAD+]


(Homo sapiens (Human))
BDBM463917
PNG
(US10787425, Compound 44)
Show SMILES COc1cc(\C=C2/SC(=O)NC2=O)ccc1OC(=O)CCCc1ccccc1
Show InChI InChI=1S/C21H19NO5S/c1-26-17-12-15(13-18-20(24)22-21(25)28-18)10-11-16(17)27-19(23)9-5-8-14-6-3-2-4-7-14/h2-4,6-7,10-13H,5,8-9H2,1H3,(H,22,24,25)/b18-13-
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n/an/a 23.9n/an/an/an/an/an/a



INDUSTRY-ACADEMIC COOPERATION FOUNDATION CHOSUN UNIVERSITY

US Patent


Assay Description
To confirm whether the compounds according to the present disclosure have an effect of inhibiting 15-PGDH, the NADH, which appears at the wavelength ...


US Patent US10787425 (2020)

More data for this
Ligand-Target Pair
15-hydroxyprostaglandin dehydrogenase [NAD+]


(Homo sapiens (Human))
BDBM463927
PNG
(US10787425, Compound 53)
Show SMILES CCOc1cc(\C=C2/SC(=O)NC2=O)ccc1OC(=O)CCC1CCCCC1
Show InChI InChI=1S/C21H25NO5S/c1-2-26-17-12-15(13-18-20(24)22-21(25)28-18)8-10-16(17)27-19(23)11-9-14-6-4-3-5-7-14/h8,10,12-14H,2-7,9,11H2,1H3,(H,22,24,25)/b18-13-
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n/an/a 24.5n/an/an/an/an/an/a



INDUSTRY-ACADEMIC COOPERATION FOUNDATION CHOSUN UNIVERSITY

US Patent


Assay Description
To confirm whether the compounds according to the present disclosure have an effect of inhibiting 15-PGDH, the NADH, which appears at the wavelength ...


US Patent US10787425 (2020)

More data for this
Ligand-Target Pair
15-hydroxyprostaglandin dehydrogenase [NAD+]


(Homo sapiens (Human))
BDBM463963
PNG
(US10787425, Compound 89)
Show SMILES Clc1c(OC(=O)CCCc2ccccc2)cccc1\C=C1/SC(=O)NC1=O
Show InChI InChI=1S/C20H16ClNO4S/c21-18-14(12-16-19(24)22-20(25)27-16)9-5-10-15(18)26-17(23)11-4-8-13-6-2-1-3-7-13/h1-3,5-7,9-10,12H,4,8,11H2,(H,22,24,25)/b16-12-
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n/an/a 25.1n/an/an/an/an/an/a



INDUSTRY-ACADEMIC COOPERATION FOUNDATION CHOSUN UNIVERSITY

US Patent


Assay Description
To confirm whether the compounds according to the present disclosure have an effect of inhibiting 15-PGDH, the NADH, which appears at the wavelength ...


US Patent US10787425 (2020)

More data for this
Ligand-Target Pair
15-hydroxyprostaglandin dehydrogenase [NAD+]


(Homo sapiens (Human))
BDBM463899
PNG
(US10787425, Compound 26)
Show SMILES Brc1cc(\C=C2/SC(=O)NC2=O)ccc1OC(=O)c1ccccc1
Show InChI InChI=1S/C17H10BrNO4S/c18-12-8-10(9-14-15(20)19-17(22)24-14)6-7-13(12)23-16(21)11-4-2-1-3-5-11/h1-9H,(H,19,20,22)/b14-9-
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n/an/a 25.4n/an/an/an/an/an/a



INDUSTRY-ACADEMIC COOPERATION FOUNDATION CHOSUN UNIVERSITY

US Patent


Assay Description
To confirm whether the compounds according to the present disclosure have an effect of inhibiting 15-PGDH, the NADH, which appears at the wavelength ...


US Patent US10787425 (2020)

More data for this
Ligand-Target Pair
15-hydroxyprostaglandin dehydrogenase [NAD+]


(Homo sapiens (Human))
BDBM463959
PNG
(US10787425, Compound 85)
Show SMILES Clc1c(OC(=O)CCCCC2CCCCC2)cccc1\C=C1/SC(=O)NC1=O
Show InChI InChI=1S/C21H24ClNO4S/c22-19-15(13-17-20(25)23-21(26)28-17)10-6-11-16(19)27-18(24)12-5-4-9-14-7-2-1-3-8-14/h6,10-11,13-14H,1-5,7-9,12H2,(H,23,25,26)/b17-13-
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n/an/a 25.6n/an/an/an/an/an/a



INDUSTRY-ACADEMIC COOPERATION FOUNDATION CHOSUN UNIVERSITY

US Patent


Assay Description
To confirm whether the compounds according to the present disclosure have an effect of inhibiting 15-PGDH, the NADH, which appears at the wavelength ...


US Patent US10787425 (2020)

More data for this
Ligand-Target Pair
15-hydroxyprostaglandin dehydrogenase [NAD+]


(Homo sapiens (Human))
BDBM463943
PNG
(US10787425, Compound 69)
Show SMILES O=C(CCCC1CCCCC1)Oc1ccc(\C=C2/SC(=O)NC2=O)cc1
Show InChI InChI=1S/C20H23NO4S/c22-18(8-4-7-14-5-2-1-3-6-14)25-16-11-9-15(10-12-16)13-17-19(23)21-20(24)26-17/h9-14H,1-8H2,(H,21,23,24)/b17-13-
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n/an/a 26.1n/an/an/an/an/an/a



INDUSTRY-ACADEMIC COOPERATION FOUNDATION CHOSUN UNIVERSITY

US Patent


Assay Description
To confirm whether the compounds according to the present disclosure have an effect of inhibiting 15-PGDH, the NADH, which appears at the wavelength ...


US Patent US10787425 (2020)

More data for this
Ligand-Target Pair
15-hydroxyprostaglandin dehydrogenase [NAD+]


(Homo sapiens (Human))
BDBM463898
PNG
(US10787425, Compound 25)
Show SMILES Cc1cc(\C=C2/SC(=O)NC2=O)ccc1OC(=O)CCCCC1CCCCC1
Show InChI InChI=1S/C22H27NO4S/c1-15-13-17(14-19-21(25)23-22(26)28-19)11-12-18(15)27-20(24)10-6-5-9-16-7-3-2-4-8-16/h11-14,16H,2-10H2,1H3,(H,23,25,26)/b19-14-
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n/an/a 26.3n/an/an/an/an/an/a



INDUSTRY-ACADEMIC COOPERATION FOUNDATION CHOSUN UNIVERSITY

US Patent


Assay Description
To confirm whether the compounds according to the present disclosure have an effect of inhibiting 15-PGDH, the NADH, which appears at the wavelength ...


US Patent US10787425 (2020)

More data for this
Ligand-Target Pair
15-hydroxyprostaglandin dehydrogenase [NAD+]


(Homo sapiens (Human))
BDBM463970
PNG
(US10787425, Compound 96)
Show SMILES Clc1cc(OC(=O)C2CCCCC2)ccc1\C=C1/SC(=O)NC1=O
Show InChI InChI=1S/C17H16ClNO4S/c18-13-9-12(23-16(21)10-4-2-1-3-5-10)7-6-11(13)8-14-15(20)19-17(22)24-14/h6-10H,1-5H2,(H,19,20,22)/b14-8-
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n/an/a 26.8n/an/an/an/an/an/a



INDUSTRY-ACADEMIC COOPERATION FOUNDATION CHOSUN UNIVERSITY

US Patent


Assay Description
To confirm whether the compounds according to the present disclosure have an effect of inhibiting 15-PGDH, the NADH, which appears at the wavelength ...


US Patent US10787425 (2020)

More data for this
Ligand-Target Pair
15-hydroxyprostaglandin dehydrogenase [NAD+]


(Homo sapiens (Human))
BDBM463972
PNG
(US10787425, Compound 97)
Show SMILES Clc1cc(OC(=O)CC2CCCCC2)ccc1\C=C1/SC(=O)NC1=O
Show InChI InChI=1S/C18H18ClNO4S/c19-14-10-13(24-16(21)8-11-4-2-1-3-5-11)7-6-12(14)9-15-17(22)20-18(23)25-15/h6-7,9-11H,1-5,8H2,(H,20,22,23)/b15-9-
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n/an/a 27.7n/an/an/an/an/an/a



INDUSTRY-ACADEMIC COOPERATION FOUNDATION CHOSUN UNIVERSITY

US Patent


Assay Description
To confirm whether the compounds according to the present disclosure have an effect of inhibiting 15-PGDH, the NADH, which appears at the wavelength ...


US Patent US10787425 (2020)

More data for this
Ligand-Target Pair
15-hydroxyprostaglandin dehydrogenase [NAD+]


(Homo sapiens (Human))
BDBM463910
PNG
(US10787425, Compound 37)
Show SMILES COc1cc(\C=C2/SC(=O)NC2=O)ccc1OC(=O)CC1CCCCC1
Show InChI InChI=1S/C19H21NO5S/c1-24-15-9-13(10-16-18(22)20-19(23)26-16)7-8-14(15)25-17(21)11-12-5-3-2-4-6-12/h7-10,12H,2-6,11H2,1H3,(H,20,22,23)/b16-10-
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n/an/a 27.8n/an/an/an/an/an/a



INDUSTRY-ACADEMIC COOPERATION FOUNDATION CHOSUN UNIVERSITY

US Patent


Assay Description
To confirm whether the compounds according to the present disclosure have an effect of inhibiting 15-PGDH, the NADH, which appears at the wavelength ...


US Patent US10787425 (2020)

More data for this
Ligand-Target Pair
15-hydroxyprostaglandin dehydrogenase [NAD+]


(Homo sapiens (Human))
BDBM463913
PNG
(US10787425, Compound 40)
Show SMILES COc1cc(\C=C2/SC(=O)NC2=O)ccc1OC(=O)CCCCC1CCCCC1
Show InChI InChI=1S/C22H27NO5S/c1-27-18-13-16(14-19-21(25)23-22(26)29-19)11-12-17(18)28-20(24)10-6-5-9-15-7-3-2-4-8-15/h11-15H,2-10H2,1H3,(H,23,25,26)/b19-14-
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n/an/a 28.2n/an/an/an/an/an/a



INDUSTRY-ACADEMIC COOPERATION FOUNDATION CHOSUN UNIVERSITY

US Patent


Assay Description
To confirm whether the compounds according to the present disclosure have an effect of inhibiting 15-PGDH, the NADH, which appears at the wavelength ...


US Patent US10787425 (2020)

More data for this
Ligand-Target Pair
15-hydroxyprostaglandin dehydrogenase [NAD+]


(Homo sapiens (Human))
BDBM463901
PNG
(US10787425, Compound 28)
Show SMILES Brc1cc(\C=C2/SC(=O)NC2=O)ccc1OC(=O)CCc1ccccc1
Show InChI InChI=1S/C19H14BrNO4S/c20-14-10-13(11-16-18(23)21-19(24)26-16)6-8-15(14)25-17(22)9-7-12-4-2-1-3-5-12/h1-6,8,10-11H,7,9H2,(H,21,23,24)/b16-11-
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n/an/a 28.4n/an/an/an/an/an/a



INDUSTRY-ACADEMIC COOPERATION FOUNDATION CHOSUN UNIVERSITY

US Patent


Assay Description
To confirm whether the compounds according to the present disclosure have an effect of inhibiting 15-PGDH, the NADH, which appears at the wavelength ...


US Patent US10787425 (2020)

More data for this
Ligand-Target Pair
15-hydroxyprostaglandin dehydrogenase [NAD+]


(Homo sapiens (Human))
BDBM463916
PNG
(US10787425, Compound 43)
Show SMILES COc1cc(\C=C2/SC(=O)NC2=O)ccc1OC(=O)CCc1ccccc1
Show InChI InChI=1S/C20H17NO5S/c1-25-16-11-14(12-17-19(23)21-20(24)27-17)7-9-15(16)26-18(22)10-8-13-5-3-2-4-6-13/h2-7,9,11-12H,8,10H2,1H3,(H,21,23,24)/b17-12-
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n/an/a 28.6n/an/an/an/an/an/a



INDUSTRY-ACADEMIC COOPERATION FOUNDATION CHOSUN UNIVERSITY

US Patent


Assay Description
To confirm whether the compounds according to the present disclosure have an effect of inhibiting 15-PGDH, the NADH, which appears at the wavelength ...


US Patent US10787425 (2020)

More data for this
Ligand-Target Pair
15-hydroxyprostaglandin dehydrogenase [NAD+]


(Homo sapiens (Human))
BDBM463923
PNG
(US10787425, Compound 50)
Show SMILES CCOc1cc(\C=C2/SC(=O)NC2=O)ccc1OC(=O)CCC1CCCC1
Show InChI InChI=1S/C20H23NO5S/c1-2-25-16-11-14(12-17-19(23)21-20(24)27-17)7-9-15(16)26-18(22)10-8-13-5-3-4-6-13/h7,9,11-13H,2-6,8,10H2,1H3,(H,21,23,24)/b17-12-
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n/an/a 29n/an/an/an/an/an/a



INDUSTRY-ACADEMIC COOPERATION FOUNDATION CHOSUN UNIVERSITY

US Patent


Assay Description
To confirm whether the compounds according to the present disclosure have an effect of inhibiting 15-PGDH, the NADH, which appears at the wavelength ...


US Patent US10787425 (2020)

More data for this
Ligand-Target Pair
15-hydroxyprostaglandin dehydrogenase [NAD+]


(Homo sapiens (Human))
BDBM463878
PNG
(US10787425, Compound 5)
Show SMILES Clc1cc(\C=C2/SC(=O)NC2=O)ccc1OC(=O)CCC1CCCC1
Show InChI InChI=1S/C18H18ClNO4S/c19-13-9-12(10-15-17(22)20-18(23)25-15)5-7-14(13)24-16(21)8-6-11-3-1-2-4-11/h5,7,9-11H,1-4,6,8H2,(H,20,22,23)/b15-10-
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n/an/a 30.5n/an/an/an/an/an/a



INDUSTRY-ACADEMIC COOPERATION FOUNDATION CHOSUN UNIVERSITY

US Patent


Assay Description
To confirm whether the compounds according to the present disclosure have an effect of inhibiting 15-PGDH, the NADH, which appears at the wavelength ...


US Patent US10787425 (2020)

More data for this
Ligand-Target Pair
15-hydroxyprostaglandin dehydrogenase [NAD+]


(Homo sapiens (Human))
BDBM463941
PNG
(US10787425, Compound 67)
Show SMILES O=C(CC1CCCCC1)Oc1ccc(\C=C2/SC(=O)NC2=O)cc1
Show InChI InChI=1S/C18H19NO4S/c20-16(11-12-4-2-1-3-5-12)23-14-8-6-13(7-9-14)10-15-17(21)19-18(22)24-15/h6-10,12H,1-5,11H2,(H,19,21,22)/b15-10-
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n/an/a 30.5n/an/an/an/an/an/a



INDUSTRY-ACADEMIC COOPERATION FOUNDATION CHOSUN UNIVERSITY

US Patent


Assay Description
To confirm whether the compounds according to the present disclosure have an effect of inhibiting 15-PGDH, the NADH, which appears at the wavelength ...


US Patent US10787425 (2020)

More data for this
Ligand-Target Pair
15-hydroxyprostaglandin dehydrogenase [NAD+]


(Homo sapiens (Human))
BDBM463883
PNG
(US10787425, Compound 10)
Show SMILES Clc1cc(\C=C2/SC(=O)NC2=O)ccc1OC(=O)CCCCC1CCCCC1
Show InChI InChI=1S/C21H24ClNO4S/c22-16-12-15(13-18-20(25)23-21(26)28-18)10-11-17(16)27-19(24)9-5-4-8-14-6-2-1-3-7-14/h10-14H,1-9H2,(H,23,25,26)/b18-13-
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n/an/a 31.7n/an/an/an/an/an/a



INDUSTRY-ACADEMIC COOPERATION FOUNDATION CHOSUN UNIVERSITY

US Patent


Assay Description
To confirm whether the compounds according to the present disclosure have an effect of inhibiting 15-PGDH, the NADH, which appears at the wavelength ...


US Patent US10787425 (2020)

More data for this
Ligand-Target Pair
15-hydroxyprostaglandin dehydrogenase [NAD+]


(Homo sapiens (Human))
BDBM463884
PNG
(US10787425, Compound 11)
Show SMILES Clc1cc(\C=C2/SC(=O)NC2=O)ccc1OC(=O)c1ccccc1
Show InChI InChI=1S/C17H10ClNO4S/c18-12-8-10(9-14-15(20)19-17(22)24-14)6-7-13(12)23-16(21)11-4-2-1-3-5-11/h1-9H,(H,19,20,22)/b14-9-
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n/an/a 31.9n/an/an/an/an/an/a



INDUSTRY-ACADEMIC COOPERATION FOUNDATION CHOSUN UNIVERSITY

US Patent


Assay Description
To confirm whether the compounds according to the present disclosure have an effect of inhibiting 15-PGDH, the NADH, which appears at the wavelength ...


US Patent US10787425 (2020)

More data for this
Ligand-Target Pair
15-hydroxyprostaglandin dehydrogenase [NAD+]


(Homo sapiens (Human))
BDBM463974
PNG
(US10787425, Compound 98)
Show SMILES Clc1cc(OC(=O)CCC2CCCCC2)ccc1\C=C1/SC(=O)NC1=O
Show InChI InChI=1S/C19H20ClNO4S/c20-15-11-14(25-17(22)9-6-12-4-2-1-3-5-12)8-7-13(15)10-16-18(23)21-19(24)26-16/h7-8,10-12H,1-6,9H2,(H,21,23,24)/b16-10-
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n/an/a 32.4n/an/an/an/an/an/a



INDUSTRY-ACADEMIC COOPERATION FOUNDATION CHOSUN UNIVERSITY

US Patent


Assay Description
To confirm whether the compounds according to the present disclosure have an effect of inhibiting 15-PGDH, the NADH, which appears at the wavelength ...


US Patent US10787425 (2020)

More data for this
Ligand-Target Pair
15-hydroxyprostaglandin dehydrogenase [NAD+]


(Homo sapiens (Human))
BDBM463968
PNG
(US10787425, Compound 94)
Show SMILES Clc1cc(OC(=O)CC2CCCC2)ccc1\C=C1/SC(=O)NC1=O
Show InChI InChI=1S/C17H16ClNO4S/c18-13-9-12(23-15(20)7-10-3-1-2-4-10)6-5-11(13)8-14-16(21)19-17(22)24-14/h5-6,8-10H,1-4,7H2,(H,19,21,22)/b14-8-
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n/an/a 32.7n/an/an/an/an/an/a



INDUSTRY-ACADEMIC COOPERATION FOUNDATION CHOSUN UNIVERSITY

US Patent


Assay Description
To confirm whether the compounds according to the present disclosure have an effect of inhibiting 15-PGDH, the NADH, which appears at the wavelength ...


US Patent US10787425 (2020)

More data for this
Ligand-Target Pair
15-hydroxyprostaglandin dehydrogenase [NAD+]


(Homo sapiens (Human))
BDBM463956
PNG
(US10787425, Compound 82)
Show SMILES Clc1c(OC(=O)CC2CCCCC2)cccc1\C=C1/SC(=O)NC1=O
Show InChI InChI=1S/C18H18ClNO4S/c19-16-12(10-14-17(22)20-18(23)25-14)7-4-8-13(16)24-15(21)9-11-5-2-1-3-6-11/h4,7-8,10-11H,1-3,5-6,9H2,(H,20,22,23)/b14-10-
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n/an/a 32.7n/an/an/an/an/an/a



INDUSTRY-ACADEMIC COOPERATION FOUNDATION CHOSUN UNIVERSITY

US Patent


Assay Description
To confirm whether the compounds according to the present disclosure have an effect of inhibiting 15-PGDH, the NADH, which appears at the wavelength ...


US Patent US10787425 (2020)

More data for this
Ligand-Target Pair
15-hydroxyprostaglandin dehydrogenase [NAD+]


(Homo sapiens (Human))
BDBM463926
PNG
(US10787425, Compound 52)
Show SMILES CCOc1cc(\C=C2/SC(=O)NC2=O)ccc1OC(=O)CC1CCCCC1
Show InChI InChI=1S/C20H23NO5S/c1-2-25-16-10-14(11-17-19(23)21-20(24)27-17)8-9-15(16)26-18(22)12-13-6-4-3-5-7-13/h8-11,13H,2-7,12H2,1H3,(H,21,23,24)/b17-11-
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n/an/a 32.8n/an/an/an/an/an/a



INDUSTRY-ACADEMIC COOPERATION FOUNDATION CHOSUN UNIVERSITY

US Patent


Assay Description
To confirm whether the compounds according to the present disclosure have an effect of inhibiting 15-PGDH, the NADH, which appears at the wavelength ...


US Patent US10787425 (2020)

More data for this
Ligand-Target Pair
15-hydroxyprostaglandin dehydrogenase [NAD+]


(Homo sapiens (Human))
BDBM463929
PNG
(US10787425, Compound 55)
Show SMILES CCOc1cc(\C=C2/SC(=O)NC2=O)ccc1OC(=O)CCCCC1CCCCC1
Show InChI InChI=1S/C23H29NO5S/c1-2-28-19-14-17(15-20-22(26)24-23(27)30-20)12-13-18(19)29-21(25)11-7-6-10-16-8-4-3-5-9-16/h12-16H,2-11H2,1H3,(H,24,26,27)/b20-15-
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n/an/a 34.4n/an/an/an/an/an/a



INDUSTRY-ACADEMIC COOPERATION FOUNDATION CHOSUN UNIVERSITY

US Patent


Assay Description
To confirm whether the compounds according to the present disclosure have an effect of inhibiting 15-PGDH, the NADH, which appears at the wavelength ...


US Patent US10787425 (2020)

More data for this
Ligand-Target Pair
15-hydroxyprostaglandin dehydrogenase [NAD+]


(Homo sapiens (Human))
BDBM463954
PNG
(US10787425, Compound 80)
Show SMILES Clc1c(OC(=O)CCC2CCCC2)cccc1\C=C1/SC(=O)NC1=O
Show InChI InChI=1S/C18H18ClNO4S/c19-16-12(10-14-17(22)20-18(23)25-14)6-3-7-13(16)24-15(21)9-8-11-4-1-2-5-11/h3,6-7,10-11H,1-2,4-5,8-9H2,(H,20,22,23)/b14-10-
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n/an/a 34.7n/an/an/an/an/an/a



INDUSTRY-ACADEMIC COOPERATION FOUNDATION CHOSUN UNIVERSITY

US Patent


Assay Description
To confirm whether the compounds according to the present disclosure have an effect of inhibiting 15-PGDH, the NADH, which appears at the wavelength ...


US Patent US10787425 (2020)

More data for this
Ligand-Target Pair
15-hydroxyprostaglandin dehydrogenase [NAD+]


(Homo sapiens (Human))
BDBM463894
PNG
(US10787425, Compound 21)
Show SMILES Brc1cc(\C=C2/SC(=O)NC2=O)ccc1OC(=O)C1CCCCC1
Show InChI InChI=1S/C17H16BrNO4S/c18-12-8-10(9-14-15(20)19-17(22)24-14)6-7-13(12)23-16(21)11-4-2-1-3-5-11/h6-9,11H,1-5H2,(H,19,20,22)/b14-9-
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n/an/a 37.6n/an/an/an/an/an/a



INDUSTRY-ACADEMIC COOPERATION FOUNDATION CHOSUN UNIVERSITY

US Patent


Assay Description
To confirm whether the compounds according to the present disclosure have an effect of inhibiting 15-PGDH, the NADH, which appears at the wavelength ...


US Patent US10787425 (2020)

More data for this
Ligand-Target Pair
15-hydroxyprostaglandin dehydrogenase [NAD+]


(Homo sapiens (Human))
BDBM463918
PNG
(US10787425, Compound 45)
Show SMILES COc1cc(\C=C2/SC(=O)NC2=O)ccc1OC(=O)CCCCc1ccccc1
Show InChI InChI=1S/C22H21NO5S/c1-27-18-13-16(14-19-21(25)23-22(26)29-19)11-12-17(18)28-20(24)10-6-5-9-15-7-3-2-4-8-15/h2-4,7-8,11-14H,5-6,9-10H2,1H3,(H,23,25,26)/b19-14-
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n/an/a 38.9n/an/an/an/an/an/a



INDUSTRY-ACADEMIC COOPERATION FOUNDATION CHOSUN UNIVERSITY

US Patent


Assay Description
To confirm whether the compounds according to the present disclosure have an effect of inhibiting 15-PGDH, the NADH, which appears at the wavelength ...


US Patent US10787425 (2020)

More data for this
Ligand-Target Pair
15-hydroxyprostaglandin dehydrogenase [NAD+]


(Homo sapiens (Human))
BDBM463975
PNG
(US10787425, Compound 99)
Show SMILES Clc1cc(OC(=O)CCCC2CCCCC2)ccc1\C=C1/SC(=O)NC1=O
Show InChI InChI=1S/C20H22ClNO4S/c21-16-12-15(10-9-14(16)11-17-19(24)22-20(25)27-17)26-18(23)8-4-7-13-5-2-1-3-6-13/h9-13H,1-8H2,(H,22,24,25)/b17-11-
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n/an/a 39.2n/an/an/an/an/an/a



INDUSTRY-ACADEMIC COOPERATION FOUNDATION CHOSUN UNIVERSITY

US Patent


Assay Description
To confirm whether the compounds according to the present disclosure have an effect of inhibiting 15-PGDH, the NADH, which appears at the wavelength ...


US Patent US10787425 (2020)

More data for this
Ligand-Target Pair
15-hydroxyprostaglandin dehydrogenase [NAD+]


(Homo sapiens (Human))
BDBM463976
PNG
(US10787425, Compound 100)
Show SMILES Clc1cc(OC(=O)CCCCC2CCCCC2)ccc1\C=C1/SC(=O)NC1=O
Show InChI InChI=1S/C21H24ClNO4S/c22-17-13-16(11-10-15(17)12-18-20(25)23-21(26)28-18)27-19(24)9-5-4-8-14-6-2-1-3-7-14/h10-14H,1-9H2,(H,23,25,26)/b18-12-
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n/an/a 39.4n/an/an/an/an/an/a



INDUSTRY-ACADEMIC COOPERATION FOUNDATION CHOSUN UNIVERSITY

US Patent


Assay Description
To confirm whether the compounds according to the present disclosure have an effect of inhibiting 15-PGDH, the NADH, which appears at the wavelength ...


US Patent US10787425 (2020)

More data for this
Ligand-Target Pair
15-hydroxyprostaglandin dehydrogenase [NAD+]


(Homo sapiens (Human))
BDBM463900
PNG
(US10787425, Compound 27)
Show SMILES Brc1cc(\C=C2/SC(=O)NC2=O)ccc1OC(=O)Cc1ccccc1
Show InChI InChI=1S/C18H12BrNO4S/c19-13-8-12(9-15-17(22)20-18(23)25-15)6-7-14(13)24-16(21)10-11-4-2-1-3-5-11/h1-9H,10H2,(H,20,22,23)/b15-9-
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n/an/a 40.6n/an/an/an/an/an/a



INDUSTRY-ACADEMIC COOPERATION FOUNDATION CHOSUN UNIVERSITY

US Patent


Assay Description
To confirm whether the compounds according to the present disclosure have an effect of inhibiting 15-PGDH, the NADH, which appears at the wavelength ...


US Patent US10787425 (2020)

More data for this
Ligand-Target Pair
15-hydroxyprostaglandin dehydrogenase [NAD+]


(Homo sapiens (Human))
BDBM463886
PNG
(US10787425, Compound 13)
Show SMILES Clc1cc(\C=C2/SC(=O)NC2=O)ccc1OC(=O)CCc1ccccc1
Show InChI InChI=1S/C19H14ClNO4S/c20-14-10-13(11-16-18(23)21-19(24)26-16)6-8-15(14)25-17(22)9-7-12-4-2-1-3-5-12/h1-6,8,10-11H,7,9H2,(H,21,23,24)/b16-11-
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n/an/a 41.8n/an/an/an/an/an/a



INDUSTRY-ACADEMIC COOPERATION FOUNDATION CHOSUN UNIVERSITY

US Patent


Assay Description
To confirm whether the compounds according to the present disclosure have an effect of inhibiting 15-PGDH, the NADH, which appears at the wavelength ...


US Patent US10787425 (2020)

More data for this
Ligand-Target Pair
15-hydroxyprostaglandin dehydrogenase [NAD+]


(Homo sapiens (Human))
BDBM463915
PNG
(US10787425, Compound 42)
Show SMILES COc1cc(\C=C2/SC(=O)NC2=O)ccc1OC(=O)Cc1ccccc1
Show InChI InChI=1S/C19H15NO5S/c1-24-15-9-13(10-16-18(22)20-19(23)26-16)7-8-14(15)25-17(21)11-12-5-3-2-4-6-12/h2-10H,11H2,1H3,(H,20,22,23)/b16-10-
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n/an/a 42.2n/an/an/an/an/an/a



INDUSTRY-ACADEMIC COOPERATION FOUNDATION CHOSUN UNIVERSITY

US Patent


Assay Description
To confirm whether the compounds according to the present disclosure have an effect of inhibiting 15-PGDH, the NADH, which appears at the wavelength ...


US Patent US10787425 (2020)

More data for this
Ligand-Target Pair
15-hydroxyprostaglandin dehydrogenase [NAD+]


(Homo sapiens (Human))
BDBM463953
PNG
(US10787425, Compound 79)
Show SMILES Clc1c(OC(=O)CC2CCCC2)cccc1\C=C1/SC(=O)NC1=O
Show InChI InChI=1S/C17H16ClNO4S/c18-15-11(9-13-16(21)19-17(22)24-13)6-3-7-12(15)23-14(20)8-10-4-1-2-5-10/h3,6-7,9-10H,1-2,4-5,8H2,(H,19,21,22)/b13-9-
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n/an/a 42.8n/an/an/an/an/an/a



INDUSTRY-ACADEMIC COOPERATION FOUNDATION CHOSUN UNIVERSITY

US Patent


Assay Description
To confirm whether the compounds according to the present disclosure have an effect of inhibiting 15-PGDH, the NADH, which appears at the wavelength ...


US Patent US10787425 (2020)

More data for this
Ligand-Target Pair
15-hydroxyprostaglandin dehydrogenase [NAD+]


(Homo sapiens (Human))
BDBM463933
PNG
(US10787425, Compound 59)
Show SMILES CCOc1cc(\C=C2/SC(=O)NC2=O)ccc1OC(=O)CCCc1ccccc1
Show InChI InChI=1S/C22H21NO5S/c1-2-27-18-13-16(14-19-21(25)23-22(26)29-19)11-12-17(18)28-20(24)10-6-9-15-7-4-3-5-8-15/h3-5,7-8,11-14H,2,6,9-10H2,1H3,(H,23,25,26)/b19-14-
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n/an/a 43.9n/an/an/an/an/an/a



INDUSTRY-ACADEMIC COOPERATION FOUNDATION CHOSUN UNIVERSITY

US Patent


Assay Description
To confirm whether the compounds according to the present disclosure have an effect of inhibiting 15-PGDH, the NADH, which appears at the wavelength ...


US Patent US10787425 (2020)

More data for this
Ligand-Target Pair
15-hydroxyprostaglandin dehydrogenase [NAD+]


(Homo sapiens (Human))
BDBM463888
PNG
(US10787425, Compound 15)
Show SMILES Clc1cc(\C=C2/SC(=O)NC2=O)ccc1OC(=O)CCCCc1ccccc1
Show InChI InChI=1S/C21H18ClNO4S/c22-16-12-15(13-18-20(25)23-21(26)28-18)10-11-17(16)27-19(24)9-5-4-8-14-6-2-1-3-7-14/h1-3,6-7,10-13H,4-5,8-9H2,(H,23,25,26)/b18-13-
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n/an/a 44n/an/an/an/an/an/a



INDUSTRY-ACADEMIC COOPERATION FOUNDATION CHOSUN UNIVERSITY

US Patent


Assay Description
To confirm whether the compounds according to the present disclosure have an effect of inhibiting 15-PGDH, the NADH, which appears at the wavelength ...


US Patent US10787425 (2020)

More data for this
Ligand-Target Pair
15-hydroxyprostaglandin dehydrogenase [NAD+]


(Homo sapiens (Human))
BDBM463977
PNG
(US10787425, Compound 101)
Show SMILES Clc1cc(OC(=O)c2ccccc2)ccc1\C=C1/SC(=O)NC1=O
Show InChI InChI=1S/C17H10ClNO4S/c18-13-9-12(23-16(21)10-4-2-1-3-5-10)7-6-11(13)8-14-15(20)19-17(22)24-14/h1-9H,(H,19,20,22)/b14-8-
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n/an/a 45.1n/an/an/an/an/an/a



INDUSTRY-ACADEMIC COOPERATION FOUNDATION CHOSUN UNIVERSITY

US Patent


Assay Description
To confirm whether the compounds according to the present disclosure have an effect of inhibiting 15-PGDH, the NADH, which appears at the wavelength ...


US Patent US10787425 (2020)

More data for this
Ligand-Target Pair
15-hydroxyprostaglandin dehydrogenase [NAD+]


(Homo sapiens (Human))
BDBM463964
PNG
(US10787425, Compound 90)
Show SMILES Clc1c(OC(=O)CCCCc2ccccc2)cccc1\C=C1/SC(=O)NC1=O
Show InChI InChI=1S/C21H18ClNO4S/c22-19-15(13-17-20(25)23-21(26)28-17)10-6-11-16(19)27-18(24)12-5-4-9-14-7-2-1-3-8-14/h1-3,6-8,10-11,13H,4-5,9,12H2,(H,23,25,26)/b17-13-
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n/an/a 46n/an/an/an/an/an/a



INDUSTRY-ACADEMIC COOPERATION FOUNDATION CHOSUN UNIVERSITY

US Patent


Assay Description
To confirm whether the compounds according to the present disclosure have an effect of inhibiting 15-PGDH, the NADH, which appears at the wavelength ...


US Patent US10787425 (2020)

More data for this
Ligand-Target Pair
15-hydroxyprostaglandin dehydrogenase [NAD+]


(Homo sapiens (Human))
BDBM463891
PNG
(US10787425, Compound 18)
Show SMILES Brc1cc(\C=C2/SC(=O)NC2=O)ccc1OC(=O)C1CCCC1
Show InChI InChI=1S/C16H14BrNO4S/c17-11-7-9(8-13-14(19)18-16(21)23-13)5-6-12(11)22-15(20)10-3-1-2-4-10/h5-8,10H,1-4H2,(H,18,19,21)/b13-8-
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n/an/a 50n/an/an/an/an/an/a



INDUSTRY-ACADEMIC COOPERATION FOUNDATION CHOSUN UNIVERSITY

US Patent


Assay Description
To confirm whether the compounds according to the present disclosure have an effect of inhibiting 15-PGDH, the NADH, which appears at the wavelength ...


US Patent US10787425 (2020)

More data for this
Ligand-Target Pair
15-hydroxyprostaglandin dehydrogenase [NAD+]


(Homo sapiens (Human))
BDBM463944
PNG
(US10787425, Compound 70)
Show SMILES O=C(CCCCC1CCCCC1)Oc1ccc(\C=C2/SC(=O)NC2=O)cc1
Show InChI InChI=1S/C21H25NO4S/c23-19(9-5-4-8-15-6-2-1-3-7-15)26-17-12-10-16(11-13-17)14-18-20(24)22-21(25)27-18/h10-15H,1-9H2,(H,22,24,25)/b18-14-
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n/an/a 50.4n/an/an/an/an/an/a



INDUSTRY-ACADEMIC COOPERATION FOUNDATION CHOSUN UNIVERSITY

US Patent


Assay Description
To confirm whether the compounds according to the present disclosure have an effect of inhibiting 15-PGDH, the NADH, which appears at the wavelength ...


US Patent US10787425 (2020)

More data for this
Ligand-Target Pair
15-hydroxyprostaglandin dehydrogenase [NAD+]


(Homo sapiens (Human))
BDBM463948
PNG
(US10787425, Compound 74)
Show SMILES O=C(CCCc1ccccc1)Oc1ccc(\C=C2/SC(=O)NC2=O)cc1
Show InChI InChI=1S/C20H17NO4S/c22-18(8-4-7-14-5-2-1-3-6-14)25-16-11-9-15(10-12-16)13-17-19(23)21-20(24)26-17/h1-3,5-6,9-13H,4,7-8H2,(H,21,23,24)/b17-13-
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n/an/a 50.7n/an/an/an/an/an/a



INDUSTRY-ACADEMIC COOPERATION FOUNDATION CHOSUN UNIVERSITY

US Patent


Assay Description
To confirm whether the compounds according to the present disclosure have an effect of inhibiting 15-PGDH, the NADH, which appears at the wavelength ...


US Patent US10787425 (2020)

More data for this
Ligand-Target Pair
15-hydroxyprostaglandin dehydrogenase [NAD+]


(Homo sapiens (Human))
BDBM463969
PNG
(US10787425, Compound 95)
Show SMILES Clc1cc(OC(=O)CCC2CCCC2)ccc1\C=C1/SC(=O)NC1=O
Show InChI InChI=1S/C18H18ClNO4S/c19-14-10-13(24-16(21)8-5-11-3-1-2-4-11)7-6-12(14)9-15-17(22)20-18(23)25-15/h6-7,9-11H,1-5,8H2,(H,20,22,23)/b15-9-
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n/an/a 50.8n/an/an/an/an/an/a



INDUSTRY-ACADEMIC COOPERATION FOUNDATION CHOSUN UNIVERSITY

US Patent


Assay Description
To confirm whether the compounds according to the present disclosure have an effect of inhibiting 15-PGDH, the NADH, which appears at the wavelength ...


US Patent US10787425 (2020)

More data for this
Ligand-Target Pair
15-hydroxyprostaglandin dehydrogenase [NAD+]


(Homo sapiens (Human))
BDBM463938
PNG
(US10787425, Compound 64)
Show SMILES O=C(CC1CCCC1)Oc1ccc(\C=C2/SC(=O)NC2=O)cc1
Show InChI InChI=1S/C17H17NO4S/c19-15(10-11-3-1-2-4-11)22-13-7-5-12(6-8-13)9-14-16(20)18-17(21)23-14/h5-9,11H,1-4,10H2,(H,18,20,21)/b14-9-
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n/an/a 52.1n/an/an/an/an/an/a



INDUSTRY-ACADEMIC COOPERATION FOUNDATION CHOSUN UNIVERSITY

US Patent


Assay Description
To confirm whether the compounds according to the present disclosure have an effect of inhibiting 15-PGDH, the NADH, which appears at the wavelength ...


US Patent US10787425 (2020)

More data for this
Ligand-Target Pair
15-hydroxyprostaglandin dehydrogenase [NAD+]


(Homo sapiens (Human))
BDBM463960
PNG
(US10787425, Compound 86)
Show SMILES Clc1c(OC(=O)c2ccccc2)cccc1\C=C1/SC(=O)NC1=O
Show InChI InChI=1S/C17H10ClNO4S/c18-14-11(9-13-15(20)19-17(22)24-13)7-4-8-12(14)23-16(21)10-5-2-1-3-6-10/h1-9H,(H,19,20,22)/b13-9-
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n/an/a 54.1n/an/an/an/an/an/a



INDUSTRY-ACADEMIC COOPERATION FOUNDATION CHOSUN UNIVERSITY

US Patent


Assay Description
To confirm whether the compounds according to the present disclosure have an effect of inhibiting 15-PGDH, the NADH, which appears at the wavelength ...


US Patent US10787425 (2020)

More data for this
Ligand-Target Pair
15-hydroxyprostaglandin dehydrogenase [NAD+]


(Homo sapiens (Human))
BDBM463947
PNG
(US10787425, Compound 73)
Show SMILES O=C(CCc1ccccc1)Oc1ccc(\C=C2/SC(=O)NC2=O)cc1
Show InChI InChI=1S/C19H15NO4S/c21-17(11-8-13-4-2-1-3-5-13)24-15-9-6-14(7-10-15)12-16-18(22)20-19(23)25-16/h1-7,9-10,12H,8,11H2,(H,20,22,23)/b16-12-
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n/an/a 54.4n/an/an/an/an/an/a



INDUSTRY-ACADEMIC COOPERATION FOUNDATION CHOSUN UNIVERSITY

US Patent


Assay Description
To confirm whether the compounds according to the present disclosure have an effect of inhibiting 15-PGDH, the NADH, which appears at the wavelength ...


US Patent US10787425 (2020)

More data for this
Ligand-Target Pair
15-hydroxyprostaglandin dehydrogenase [NAD+]


(Homo sapiens (Human))
BDBM463955
PNG
(US10787425, Compound 81)
Show SMILES Clc1c(OC(=O)C2CCCCC2)cccc1\C=C1/SC(=O)NC1=O
Show InChI InChI=1S/C17H16ClNO4S/c18-14-11(9-13-15(20)19-17(22)24-13)7-4-8-12(14)23-16(21)10-5-2-1-3-6-10/h4,7-10H,1-3,5-6H2,(H,19,20,22)/b13-9-
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n/an/a 55.8n/an/an/an/an/an/a



INDUSTRY-ACADEMIC COOPERATION FOUNDATION CHOSUN UNIVERSITY

US Patent


Assay Description
To confirm whether the compounds according to the present disclosure have an effect of inhibiting 15-PGDH, the NADH, which appears at the wavelength ...


US Patent US10787425 (2020)

More data for this
Ligand-Target Pair
15-hydroxyprostaglandin dehydrogenase [NAD+]


(Homo sapiens (Human))
BDBM463952
PNG
(US10787425, Compound 78)
Show SMILES Clc1c(OC(=O)C2CCCC2)cccc1\C=C1/SC(=O)NC1=O
Show InChI InChI=1S/C16H14ClNO4S/c17-13-10(8-12-14(19)18-16(21)23-12)6-3-7-11(13)22-15(20)9-4-1-2-5-9/h3,6-9H,1-2,4-5H2,(H,18,19,21)/b12-8-
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n/an/a 56.2n/an/an/an/an/an/a



INDUSTRY-ACADEMIC COOPERATION FOUNDATION CHOSUN UNIVERSITY

US Patent


Assay Description
To confirm whether the compounds according to the present disclosure have an effect of inhibiting 15-PGDH, the NADH, which appears at the wavelength ...


US Patent US10787425 (2020)

More data for this
Ligand-Target Pair
15-hydroxyprostaglandin dehydrogenase [NAD+]


(Homo sapiens (Human))
BDBM463934
PNG
(US10787425, Compound 60)
Show SMILES CCOc1cc(\C=C2/SC(=O)NC2=O)ccc1OC(=O)CCCCc1ccccc1
Show InChI InChI=1S/C23H23NO5S/c1-2-28-19-14-17(15-20-22(26)24-23(27)30-20)12-13-18(19)29-21(25)11-7-6-10-16-8-4-3-5-9-16/h3-5,8-9,12-15H,2,6-7,10-11H2,1H3,(H,24,26,27)/b20-15-
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n/an/a 58.4n/an/an/an/an/an/a



INDUSTRY-ACADEMIC COOPERATION FOUNDATION CHOSUN UNIVERSITY

US Patent


Assay Description
To confirm whether the compounds according to the present disclosure have an effect of inhibiting 15-PGDH, the NADH, which appears at the wavelength ...


US Patent US10787425 (2020)

More data for this
Ligand-Target Pair
15-hydroxyprostaglandin dehydrogenase [NAD+]


(Homo sapiens (Human))
BDBM463907
PNG
(US10787425, Compound 34)
Show SMILES CC(=O)c1cc(\C=C2/SC(=O)NC2=O)ccc1OC(=O)CC1CCCC1
Show InChI InChI=1S/C19H19NO5S/c1-11(21)14-8-13(9-16-18(23)20-19(24)26-16)6-7-15(14)25-17(22)10-12-4-2-3-5-12/h6-9,12H,2-5,10H2,1H3,(H,20,23,24)/b16-9-
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n/an/a 60.2n/an/an/an/an/an/a



INDUSTRY-ACADEMIC COOPERATION FOUNDATION CHOSUN UNIVERSITY

US Patent


Assay Description
To confirm whether the compounds according to the present disclosure have an effect of inhibiting 15-PGDH, the NADH, which appears at the wavelength ...


US Patent US10787425 (2020)

More data for this
Ligand-Target Pair
15-hydroxyprostaglandin dehydrogenase [NAD+]


(Homo sapiens (Human))
BDBM463885
PNG
(US10787425, Compound 12)
Show SMILES Clc1cc(\C=C2/SC(=O)NC2=O)ccc1OC(=O)Cc1ccccc1
Show InChI InChI=1S/C18H12ClNO4S/c19-13-8-12(9-15-17(22)20-18(23)25-15)6-7-14(13)24-16(21)10-11-4-2-1-3-5-11/h1-9H,10H2,(H,20,22,23)/b15-9-
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n/an/a 63.5n/an/an/an/an/an/a



INDUSTRY-ACADEMIC COOPERATION FOUNDATION CHOSUN UNIVERSITY

US Patent


Assay Description
To confirm whether the compounds according to the present disclosure have an effect of inhibiting 15-PGDH, the NADH, which appears at the wavelength ...


US Patent US10787425 (2020)

More data for this
Ligand-Target Pair
15-hydroxyprostaglandin dehydrogenase [NAD+]


(Homo sapiens (Human))
BDBM463967
PNG
(US10787425, Compound 93)
Show SMILES Clc1cc(OC(=O)C2CCCC2)ccc1\C=C1/SC(=O)NC1=O
Show InChI InChI=1S/C16H14ClNO4S/c17-12-8-11(22-15(20)9-3-1-2-4-9)6-5-10(12)7-13-14(19)18-16(21)23-13/h5-9H,1-4H2,(H,18,19,21)/b13-7-
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n/an/a 71n/an/an/an/an/an/a



INDUSTRY-ACADEMIC COOPERATION FOUNDATION CHOSUN UNIVERSITY

US Patent


Assay Description
To confirm whether the compounds according to the present disclosure have an effect of inhibiting 15-PGDH, the NADH, which appears at the wavelength ...


US Patent US10787425 (2020)

More data for this
Ligand-Target Pair
15-hydroxyprostaglandin dehydrogenase [NAD+]


(Homo sapiens (Human))
BDBM463981
PNG
(US10787425, Compound 104)
Show SMILES Clc1cc(OC(=O)CCCc2ccccc2)ccc1\C=C1/SC(=O)NC1=O
Show InChI InChI=1S/C20H16ClNO4S/c21-16-12-15(10-9-14(16)11-17-19(24)22-20(25)27-17)26-18(23)8-4-7-13-5-2-1-3-6-13/h1-3,5-6,9-12H,4,7-8H2,(H,22,24,25)/b17-11-
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n/an/a 74.9n/an/an/an/an/an/a



INDUSTRY-ACADEMIC COOPERATION FOUNDATION CHOSUN UNIVERSITY

US Patent


Assay Description
To confirm whether the compounds according to the present disclosure have an effect of inhibiting 15-PGDH, the NADH, which appears at the wavelength ...


US Patent US10787425 (2020)

More data for this
Ligand-Target Pair
15-hydroxyprostaglandin dehydrogenase [NAD+]


(Homo sapiens (Human))
BDBM463979
PNG
(US10787425, Compound 102)
Show SMILES Clc1cc(OC(=O)Cc2ccccc2)ccc1\C=C1/SC(=O)NC1=O
Show InChI InChI=1S/C18H12ClNO4S/c19-14-10-13(24-16(21)8-11-4-2-1-3-5-11)7-6-12(14)9-15-17(22)20-18(23)25-15/h1-7,9-10H,8H2,(H,20,22,23)/b15-9-
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n/an/a 75.3n/an/an/an/an/an/a



INDUSTRY-ACADEMIC COOPERATION FOUNDATION CHOSUN UNIVERSITY

US Patent


Assay Description
To confirm whether the compounds according to the present disclosure have an effect of inhibiting 15-PGDH, the NADH, which appears at the wavelength ...


US Patent US10787425 (2020)

More data for this
Ligand-Target Pair
15-hydroxyprostaglandin dehydrogenase [NAD+]


(Homo sapiens (Human))
BDBM463877
PNG
(US10787425, Compound 4)
Show SMILES Clc1cc(\C=C2/SC(=O)NC2=O)ccc1OC(=O)CC1CCCC1
Show InChI InChI=1S/C17H16ClNO4S/c18-12-7-11(8-14-16(21)19-17(22)24-14)5-6-13(12)23-15(20)9-10-3-1-2-4-10/h5-8,10H,1-4,9H2,(H,19,21,22)/b14-8-
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n/an/a 78.3n/an/an/an/an/an/a



INDUSTRY-ACADEMIC COOPERATION FOUNDATION CHOSUN UNIVERSITY

US Patent


Assay Description
To confirm whether the compounds according to the present disclosure have an effect of inhibiting 15-PGDH, the NADH, which appears at the wavelength ...


US Patent US10787425 (2020)

More data for this
Ligand-Target Pair
15-hydroxyprostaglandin dehydrogenase [NAD+]


(Homo sapiens (Human))
BDBM463980
PNG
(US10787425, Compound 103)
Show SMILES Clc1cc(OC(=O)CCc2ccccc2)ccc1\C=C1/SC(=O)NC1=O
Show InChI InChI=1S/C19H14ClNO4S/c20-15-11-14(25-17(22)9-6-12-4-2-1-3-5-12)8-7-13(15)10-16-18(23)21-19(24)26-16/h1-5,7-8,10-11H,6,9H2,(H,21,23,24)/b16-10-
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n/an/a 87.5n/an/an/an/an/an/a



INDUSTRY-ACADEMIC COOPERATION FOUNDATION CHOSUN UNIVERSITY

US Patent


Assay Description
To confirm whether the compounds according to the present disclosure have an effect of inhibiting 15-PGDH, the NADH, which appears at the wavelength ...


US Patent US10787425 (2020)

More data for this
Ligand-Target Pair
15-hydroxyprostaglandin dehydrogenase [NAD+]


(Homo sapiens (Human))
BDBM463940
PNG
(US10787425, Compound 66)
Show SMILES O=C(Oc1ccc(\C=C2/SC(=O)NC2=O)cc1)C1CCCCC1
Show InChI InChI=1S/C17H17NO4S/c19-15-14(23-17(21)18-15)10-11-6-8-13(9-7-11)22-16(20)12-4-2-1-3-5-12/h6-10,12H,1-5H2,(H,18,19,21)/b14-10-
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n/an/a 88.8n/an/an/an/an/an/a



INDUSTRY-ACADEMIC COOPERATION FOUNDATION CHOSUN UNIVERSITY

US Patent


Assay Description
To confirm whether the compounds according to the present disclosure have an effect of inhibiting 15-PGDH, the NADH, which appears at the wavelength ...


US Patent US10787425 (2020)

More data for this
Ligand-Target Pair
15-hydroxyprostaglandin dehydrogenase [NAD+]


(Homo sapiens (Human))
BDBM463949
PNG
(US10787425, Compound 75)
Show SMILES O=C(CCCCc1ccccc1)Oc1ccc(\C=C2/SC(=O)NC2=O)cc1
Show InChI InChI=1S/C21H19NO4S/c23-19(9-5-4-8-15-6-2-1-3-7-15)26-17-12-10-16(11-13-17)14-18-20(24)22-21(25)27-18/h1-3,6-7,10-14H,4-5,8-9H2,(H,22,24,25)/b18-14-
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n/an/a 92.1n/an/an/an/an/an/a



INDUSTRY-ACADEMIC COOPERATION FOUNDATION CHOSUN UNIVERSITY

US Patent


Assay Description
To confirm whether the compounds according to the present disclosure have an effect of inhibiting 15-PGDH, the NADH, which appears at the wavelength ...


US Patent US10787425 (2020)

More data for this
Ligand-Target Pair
15-hydroxyprostaglandin dehydrogenase [NAD+]


(Homo sapiens (Human))
BDBM463932
PNG
(US10787425, Compound 58)
Show SMILES CCOc1cc(\C=C2/SC(=O)NC2=O)ccc1OC(=O)CCc1ccccc1
Show InChI InChI=1S/C21H19NO5S/c1-2-26-17-12-15(13-18-20(24)22-21(25)28-18)8-10-16(17)27-19(23)11-9-14-6-4-3-5-7-14/h3-8,10,12-13H,2,9,11H2,1H3,(H,22,24,25)/b18-13-
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n/an/a 94.3n/an/an/an/an/an/a



INDUSTRY-ACADEMIC COOPERATION FOUNDATION CHOSUN UNIVERSITY

US Patent


Assay Description
To confirm whether the compounds according to the present disclosure have an effect of inhibiting 15-PGDH, the NADH, which appears at the wavelength ...


US Patent US10787425 (2020)

More data for this
Ligand-Target Pair
15-hydroxyprostaglandin dehydrogenase [NAD+]


(Homo sapiens (Human))
BDBM463961
PNG
(US10787425, Compound 87)
Show SMILES Clc1c(OC(=O)Cc2ccccc2)cccc1\C=C1/SC(=O)NC1=O
Show InChI InChI=1S/C18H12ClNO4S/c19-16-12(10-14-17(22)20-18(23)25-14)7-4-8-13(16)24-15(21)9-11-5-2-1-3-6-11/h1-8,10H,9H2,(H,20,22,23)/b14-10-
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n/an/a 105n/an/an/an/an/an/a



INDUSTRY-ACADEMIC COOPERATION FOUNDATION CHOSUN UNIVERSITY

US Patent


Assay Description
To confirm whether the compounds according to the present disclosure have an effect of inhibiting 15-PGDH, the NADH, which appears at the wavelength ...


US Patent US10787425 (2020)

More data for this
Ligand-Target Pair
15-hydroxyprostaglandin dehydrogenase [NAD+]


(Homo sapiens (Human))
BDBM463890
PNG
(US10787425, Compound 17)
Show SMILES Brc1cc(\C=C2/SC(=O)NC2=O)ccc1OC(=O)C1CCC1
Show InChI InChI=1S/C15H12BrNO4S/c16-10-6-8(7-12-13(18)17-15(20)22-12)4-5-11(10)21-14(19)9-2-1-3-9/h4-7,9H,1-3H2,(H,17,18,20)/b12-7-
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n/an/a 106n/an/an/an/an/an/a



INDUSTRY-ACADEMIC COOPERATION FOUNDATION CHOSUN UNIVERSITY

US Patent


Assay Description
To confirm whether the compounds according to the present disclosure have an effect of inhibiting 15-PGDH, the NADH, which appears at the wavelength ...


US Patent US10787425 (2020)

More data for this
Ligand-Target Pair
15-hydroxyprostaglandin dehydrogenase [NAD+]


(Homo sapiens (Human))
BDBM463946
PNG
(US10787425, Compound 72)
Show SMILES O=C(Cc1ccccc1)Oc1ccc(\C=C2/SC(=O)NC2=O)cc1
Show InChI InChI=1S/C18H13NO4S/c20-16(11-12-4-2-1-3-5-12)23-14-8-6-13(7-9-14)10-15-17(21)19-18(22)24-15/h1-10H,11H2,(H,19,21,22)/b15-10-
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n/an/a 108n/an/an/an/an/an/a



INDUSTRY-ACADEMIC COOPERATION FOUNDATION CHOSUN UNIVERSITY

US Patent


Assay Description
To confirm whether the compounds according to the present disclosure have an effect of inhibiting 15-PGDH, the NADH, which appears at the wavelength ...


US Patent US10787425 (2020)

More data for this
Ligand-Target Pair
15-hydroxyprostaglandin dehydrogenase [NAD+]


(Homo sapiens (Human))
BDBM463931
PNG
(US10787425, Compound 57)
Show SMILES CCOc1cc(\C=C2/SC(=O)NC2=O)ccc1OC(=O)Cc1ccccc1
Show InChI InChI=1S/C20H17NO5S/c1-2-25-16-10-14(11-17-19(23)21-20(24)27-17)8-9-15(16)26-18(22)12-13-6-4-3-5-7-13/h3-11H,2,12H2,1H3,(H,21,23,24)/b17-11-
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n/an/a 118n/an/an/an/an/an/a



INDUSTRY-ACADEMIC COOPERATION FOUNDATION CHOSUN UNIVERSITY

US Patent


Assay Description
To confirm whether the compounds according to the present disclosure have an effect of inhibiting 15-PGDH, the NADH, which appears at the wavelength ...


US Patent US10787425 (2020)

More data for this
Ligand-Target Pair
15-hydroxyprostaglandin dehydrogenase [NAD+]


(Homo sapiens (Human))
BDBM463945
PNG
(US10787425, Compound 71)
Show SMILES O=C(Oc1ccc(\C=C2/SC(=O)NC2=O)cc1)c1ccccc1
Show InChI InChI=1S/C17H11NO4S/c19-15-14(23-17(21)18-15)10-11-6-8-13(9-7-11)22-16(20)12-4-2-1-3-5-12/h1-10H,(H,18,19,21)/b14-10-
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n/an/a 124n/an/an/an/an/an/a



INDUSTRY-ACADEMIC COOPERATION FOUNDATION CHOSUN UNIVERSITY

US Patent


Assay Description
To confirm whether the compounds according to the present disclosure have an effect of inhibiting 15-PGDH, the NADH, which appears at the wavelength ...


US Patent US10787425 (2020)

More data for this
Ligand-Target Pair
15-hydroxyprostaglandin dehydrogenase [NAD+]


(Homo sapiens (Human))
BDBM463922
PNG
(US10787425, Compound 49)
Show SMILES CCOc1cc(\C=C2/SC(=O)NC2=O)ccc1OC(=O)CC1CCCC1
Show InChI InChI=1S/C19H21NO5S/c1-2-24-15-9-13(10-16-18(22)20-19(23)26-16)7-8-14(15)25-17(21)11-12-5-3-4-6-12/h7-10,12H,2-6,11H2,1H3,(H,20,22,23)/b16-10-
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n/an/a 128n/an/an/an/an/an/a



INDUSTRY-ACADEMIC COOPERATION FOUNDATION CHOSUN UNIVERSITY

US Patent


Assay Description
To confirm whether the compounds according to the present disclosure have an effect of inhibiting 15-PGDH, the NADH, which appears at the wavelength ...


US Patent US10787425 (2020)

More data for this
Ligand-Target Pair
15-hydroxyprostaglandin dehydrogenase [NAD+]


(Homo sapiens (Human))
BDBM463982
PNG
(US10787425, Compound 105)
Show SMILES CCCCCC(=O)Oc1ccc(\C=C2/SC(=O)NC2=O)c(Cl)c1
Show InChI InChI=1S/C16H16ClNO4S/c1-2-3-4-5-14(19)22-11-7-6-10(12(17)9-11)8-13-15(20)18-16(21)23-13/h6-9H,2-5H2,1H3,(H,18,20,21)/b13-8-
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n/an/a 130n/an/an/an/an/an/a



INDUSTRY-ACADEMIC COOPERATION FOUNDATION CHOSUN UNIVERSITY

US Patent


Assay Description
To confirm whether the compounds according to the present disclosure have an effect of inhibiting 15-PGDH, the NADH, which appears at the wavelength ...


US Patent US10787425 (2020)

More data for this
Ligand-Target Pair
15-hydroxyprostaglandin dehydrogenase [NAD+]


(Homo sapiens (Human))
BDBM463879
PNG
(US10787425, Compound 6)
Show SMILES Clc1cc(\C=C2/SC(=O)NC2=O)ccc1OC(=O)C1CCCCC1
Show InChI InChI=1S/C17H16ClNO4S/c18-12-8-10(9-14-15(20)19-17(22)24-14)6-7-13(12)23-16(21)11-4-2-1-3-5-11/h6-9,11H,1-5H2,(H,19,20,22)/b14-9-
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n/an/a 137n/an/an/an/an/an/a



INDUSTRY-ACADEMIC COOPERATION FOUNDATION CHOSUN UNIVERSITY

US Patent


Assay Description
To confirm whether the compounds according to the present disclosure have an effect of inhibiting 15-PGDH, the NADH, which appears at the wavelength ...


US Patent US10787425 (2020)

More data for this
Ligand-Target Pair
15-hydroxyprostaglandin dehydrogenase [NAD+]


(Homo sapiens (Human))
BDBM463914
PNG
(US10787425, Compound 41)
Show SMILES COc1cc(\C=C2/SC(=O)NC2=O)ccc1OC(=O)c1ccccc1
Show InChI InChI=1S/C18H13NO5S/c1-23-14-9-11(10-15-16(20)19-18(22)25-15)7-8-13(14)24-17(21)12-5-3-2-4-6-12/h2-10H,1H3,(H,19,20,22)/b15-10-
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n/an/a 151n/an/an/an/an/an/a



INDUSTRY-ACADEMIC COOPERATION FOUNDATION CHOSUN UNIVERSITY

US Patent


Assay Description
To confirm whether the compounds according to the present disclosure have an effect of inhibiting 15-PGDH, the NADH, which appears at the wavelength ...


US Patent US10787425 (2020)

More data for this
Ligand-Target Pair
15-hydroxyprostaglandin dehydrogenase [NAD+]


(Homo sapiens (Human))
BDBM463937
PNG
(US10787425, Compound 63)
Show SMILES O=C(Oc1ccc(\C=C2/SC(=O)NC2=O)cc1)C1CCCC1
Show InChI InChI=1S/C16H15NO4S/c18-14-13(22-16(20)17-14)9-10-5-7-12(8-6-10)21-15(19)11-3-1-2-4-11/h5-9,11H,1-4H2,(H,17,18,20)/b13-9-
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n/an/a 179n/an/an/an/an/an/a



INDUSTRY-ACADEMIC COOPERATION FOUNDATION CHOSUN UNIVERSITY

US Patent


Assay Description
To confirm whether the compounds according to the present disclosure have an effect of inhibiting 15-PGDH, the NADH, which appears at the wavelength ...


US Patent US10787425 (2020)

More data for this
Ligand-Target Pair
15-hydroxyprostaglandin dehydrogenase [NAD+]


(Homo sapiens (Human))
BDBM463876
PNG
(US10787425, Compound 3)
Show SMILES Clc1cc(\C=C2/SC(=O)NC2=O)ccc1OC(=O)C1CCCC1
Show InChI InChI=1S/C16H14ClNO4S/c17-11-7-9(8-13-14(19)18-16(21)23-13)5-6-12(11)22-15(20)10-3-1-2-4-10/h5-8,10H,1-4H2,(H,18,19,21)/b13-8-
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n/an/a 196n/an/an/an/an/an/a



INDUSTRY-ACADEMIC COOPERATION FOUNDATION CHOSUN UNIVERSITY

US Patent


Assay Description
To confirm whether the compounds according to the present disclosure have an effect of inhibiting 15-PGDH, the NADH, which appears at the wavelength ...


US Patent US10787425 (2020)

More data for this
Ligand-Target Pair
15-hydroxyprostaglandin dehydrogenase [NAD+]


(Homo sapiens (Human))
BDBM463966
PNG
(US10787425, Compound 92)
Show SMILES Clc1cc(OC(=O)C2CCC2)ccc1\C=C1/SC(=O)NC1=O
Show InChI InChI=1S/C15H12ClNO4S/c16-11-7-10(21-14(19)8-2-1-3-8)5-4-9(11)6-12-13(18)17-15(20)22-12/h4-8H,1-3H2,(H,17,18,20)/b12-6-
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n/an/a 206n/an/an/an/an/an/a



INDUSTRY-ACADEMIC COOPERATION FOUNDATION CHOSUN UNIVERSITY

US Patent


Assay Description
To confirm whether the compounds according to the present disclosure have an effect of inhibiting 15-PGDH, the NADH, which appears at the wavelength ...


US Patent US10787425 (2020)

More data for this
Ligand-Target Pair
15-hydroxyprostaglandin dehydrogenase [NAD+]


(Homo sapiens (Human))
BDBM463889
PNG
(US10787425, Compound 16)
Show SMILES Brc1cc(\C=C2/SC(=O)NC2=O)ccc1OC(=O)C1CC1
Show InChI InChI=1S/C14H10BrNO4S/c15-9-5-7(6-11-12(17)16-14(19)21-11)1-4-10(9)20-13(18)8-2-3-8/h1,4-6,8H,2-3H2,(H,16,17,19)/b11-6-
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n/an/a 220n/an/an/an/an/an/a



INDUSTRY-ACADEMIC COOPERATION FOUNDATION CHOSUN UNIVERSITY

US Patent


Assay Description
To confirm whether the compounds according to the present disclosure have an effect of inhibiting 15-PGDH, the NADH, which appears at the wavelength ...


US Patent US10787425 (2020)

More data for this
Ligand-Target Pair
15-hydroxyprostaglandin dehydrogenase [NAD+]


(Homo sapiens (Human))
BDBM463909
PNG
(US10787425, Compound 36)
Show SMILES COc1cc(\C=C2/SC(=O)NC2=O)ccc1OC(=O)C1CCCCC1
Show InChI InChI=1S/C18H19NO5S/c1-23-14-9-11(10-15-16(20)19-18(22)25-15)7-8-13(14)24-17(21)12-5-3-2-4-6-12/h7-10,12H,2-6H2,1H3,(H,19,20,22)/b15-10-
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n/an/a 242n/an/an/an/an/an/a



INDUSTRY-ACADEMIC COOPERATION FOUNDATION CHOSUN UNIVERSITY

US Patent


Assay Description
To confirm whether the compounds according to the present disclosure have an effect of inhibiting 15-PGDH, the NADH, which appears at the wavelength ...


US Patent US10787425 (2020)

More data for this
Ligand-Target Pair
15-hydroxyprostaglandin dehydrogenase [NAD+]


(Homo sapiens (Human))
BDBM463930
PNG
(US10787425, Compound 56)
Show SMILES CCOc1cc(\C=C2/SC(=O)NC2=O)ccc1OC(=O)c1ccccc1
Show InChI InChI=1S/C19H15NO5S/c1-2-24-15-10-12(11-16-17(21)20-19(23)26-16)8-9-14(15)25-18(22)13-6-4-3-5-7-13/h3-11H,2H2,1H3,(H,20,21,23)/b16-11-
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n/an/a 298n/an/an/an/an/an/a



INDUSTRY-ACADEMIC COOPERATION FOUNDATION CHOSUN UNIVERSITY

US Patent


Assay Description
To confirm whether the compounds according to the present disclosure have an effect of inhibiting 15-PGDH, the NADH, which appears at the wavelength ...


US Patent US10787425 (2020)

More data for this
Ligand-Target Pair
15-hydroxyprostaglandin dehydrogenase [NAD+]


(Homo sapiens (Human))
BDBM463936
PNG
(US10787425, Compound 62)
Show SMILES O=C(Oc1ccc(\C=C2/SC(=O)NC2=O)cc1)C1CCC1
Show InChI InChI=1S/C15H13NO4S/c17-13-12(21-15(19)16-13)8-9-4-6-11(7-5-9)20-14(18)10-2-1-3-10/h4-8,10H,1-3H2,(H,16,17,19)/b12-8-
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n/an/a 431n/an/an/an/an/an/a



INDUSTRY-ACADEMIC COOPERATION FOUNDATION CHOSUN UNIVERSITY

US Patent


Assay Description
To confirm whether the compounds according to the present disclosure have an effect of inhibiting 15-PGDH, the NADH, which appears at the wavelength ...


US Patent US10787425 (2020)

More data for this
Ligand-Target Pair
15-hydroxyprostaglandin dehydrogenase [NAD+]


(Homo sapiens (Human))
BDBM463951
PNG
(US10787425, Compound 77)
Show SMILES Clc1c(OC(=O)C2CCC2)cccc1\C=C1/SC(=O)NC1=O
Show InChI InChI=1S/C15H12ClNO4S/c16-12-9(7-11-13(18)17-15(20)22-11)5-2-6-10(12)21-14(19)8-3-1-4-8/h2,5-8H,1,3-4H2,(H,17,18,20)/b11-7-
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n/an/a 482n/an/an/an/an/an/a



INDUSTRY-ACADEMIC COOPERATION FOUNDATION CHOSUN UNIVERSITY

US Patent


Assay Description
To confirm whether the compounds according to the present disclosure have an effect of inhibiting 15-PGDH, the NADH, which appears at the wavelength ...


US Patent US10787425 (2020)

More data for this
Ligand-Target Pair
15-hydroxyprostaglandin dehydrogenase [NAD+]


(Homo sapiens (Human))
BDBM463906
PNG
(US10787425, Compound 33)
Show SMILES COc1cc(\C=C2/SC(=O)NC2=O)ccc1OC(=O)C1CCCC1
Show InChI InChI=1S/C17H17NO5S/c1-22-13-8-10(9-14-15(19)18-17(21)24-14)6-7-12(13)23-16(20)11-4-2-3-5-11/h6-9,11H,2-5H2,1H3,(H,18,19,21)/b14-9-
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n/an/a 494n/an/an/an/an/an/a



INDUSTRY-ACADEMIC COOPERATION FOUNDATION CHOSUN UNIVERSITY

US Patent


Assay Description
To confirm whether the compounds according to the present disclosure have an effect of inhibiting 15-PGDH, the NADH, which appears at the wavelength ...


US Patent US10787425 (2020)

More data for this
Ligand-Target Pair
15-hydroxyprostaglandin dehydrogenase [NAD+]


(Homo sapiens (Human))
BDBM463950
PNG
(US10787425, Compound 76)
Show SMILES Clc1c(OC(=O)C2CC2)cccc1\C=C1/SC(=O)NC1=O
Show InChI InChI=1S/C14H10ClNO4S/c15-11-8(6-10-12(17)16-14(19)21-10)2-1-3-9(11)20-13(18)7-4-5-7/h1-3,6-7H,4-5H2,(H,16,17,19)/b10-6-
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n/an/a 542n/an/an/an/an/an/a



INDUSTRY-ACADEMIC COOPERATION FOUNDATION CHOSUN UNIVERSITY

US Patent


Assay Description
To confirm whether the compounds according to the present disclosure have an effect of inhibiting 15-PGDH, the NADH, which appears at the wavelength ...


US Patent US10787425 (2020)

More data for this
Ligand-Target Pair
15-hydroxyprostaglandin dehydrogenase [NAD+]


(Homo sapiens (Human))
BDBM463925
PNG
(US10787425, Compound 51)
Show SMILES CCOc1cc(\C=C2/SC(=O)NC2=O)ccc1OC(=O)C1CCCCC1
Show InChI InChI=1S/C19H21NO5S/c1-2-24-15-10-12(11-16-17(21)20-19(23)26-16)8-9-14(15)25-18(22)13-6-4-3-5-7-13/h8-11,13H,2-7H2,1H3,(H,20,21,23)/b16-11-
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n/an/a 549n/an/an/an/an/an/a



INDUSTRY-ACADEMIC COOPERATION FOUNDATION CHOSUN UNIVERSITY

US Patent


Assay Description
To confirm whether the compounds according to the present disclosure have an effect of inhibiting 15-PGDH, the NADH, which appears at the wavelength ...


US Patent US10787425 (2020)

More data for this
Ligand-Target Pair
15-hydroxyprostaglandin dehydrogenase [NAD+]


(Homo sapiens (Human))
BDBM463875
PNG
(US10787425, Compound 2)
Show SMILES Clc1cc(\C=C2/SC(=O)NC2=O)ccc1OC(=O)C1CCC1
Show InChI InChI=1S/C15H12ClNO4S/c16-10-6-8(7-12-13(18)17-15(20)22-12)4-5-11(10)21-14(19)9-2-1-3-9/h4-7,9H,1-3H2,(H,17,18,20)/b12-7-
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n/an/a 782n/an/an/an/an/an/a



INDUSTRY-ACADEMIC COOPERATION FOUNDATION CHOSUN UNIVERSITY

US Patent


Assay Description
To confirm whether the compounds according to the present disclosure have an effect of inhibiting 15-PGDH, the NADH, which appears at the wavelength ...


US Patent US10787425 (2020)

More data for this
Ligand-Target Pair
15-hydroxyprostaglandin dehydrogenase [NAD+]


(Homo sapiens (Human))
BDBM463965
PNG
(US10787425, Compound 91)
Show SMILES Clc1cc(OC(=O)C2CC2)ccc1\C=C1/SC(=O)NC1=O
Show InChI InChI=1S/C14H10ClNO4S/c15-10-6-9(20-13(18)7-1-2-7)4-3-8(10)5-11-12(17)16-14(19)21-11/h3-7H,1-2H2,(H,16,17,19)/b11-5-
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n/an/a 1.08E+3n/an/an/an/an/an/a



INDUSTRY-ACADEMIC COOPERATION FOUNDATION CHOSUN UNIVERSITY

US Patent


Assay Description
To confirm whether the compounds according to the present disclosure have an effect of inhibiting 15-PGDH, the NADH, which appears at the wavelength ...


US Patent US10787425 (2020)

More data for this
Ligand-Target Pair
15-hydroxyprostaglandin dehydrogenase [NAD+]


(Homo sapiens (Human))
BDBM463904
PNG
(US10787425, Compound 31)
Show SMILES COc1cc(\C=C2/SC(=O)NC2=O)ccc1OC(=O)C1CC1
Show InChI InChI=1S/C15H13NO5S/c1-20-11-6-8(7-12-13(17)16-15(19)22-12)2-5-10(11)21-14(18)9-3-4-9/h2,5-7,9H,3-4H2,1H3,(H,16,17,19)/b12-7-
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n/an/a 1.10E+3n/an/an/an/an/an/a



INDUSTRY-ACADEMIC COOPERATION FOUNDATION CHOSUN UNIVERSITY

US Patent


Assay Description
To confirm whether the compounds according to the present disclosure have an effect of inhibiting 15-PGDH, the NADH, which appears at the wavelength ...


US Patent US10787425 (2020)

More data for this
Ligand-Target Pair
15-hydroxyprostaglandin dehydrogenase [NAD+]


(Homo sapiens (Human))
BDBM463905
PNG
(US10787425, Compound 32)
Show SMILES COc1cc(\C=C2/SC(=O)NC2=O)ccc1OC(=O)C1CCC1
Show InChI InChI=1S/C16H15NO5S/c1-21-12-7-9(8-13-14(18)17-16(20)23-13)5-6-11(12)22-15(19)10-3-2-4-10/h5-8,10H,2-4H2,1H3,(H,17,18,20)/b13-8-
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n/an/a 1.12E+3n/an/an/an/an/an/a



INDUSTRY-ACADEMIC COOPERATION FOUNDATION CHOSUN UNIVERSITY

US Patent


Assay Description
To confirm whether the compounds according to the present disclosure have an effect of inhibiting 15-PGDH, the NADH, which appears at the wavelength ...


US Patent US10787425 (2020)

More data for this
Ligand-Target Pair
15-hydroxyprostaglandin dehydrogenase [NAD+]


(Homo sapiens (Human))
BDBM463921
PNG
(US10787425, Compound 48)
Show SMILES CCOc1cc(\C=C2/SC(=O)NC2=O)ccc1OC(=O)C1CCCC1
Show InChI InChI=1S/C18H19NO5S/c1-2-23-14-9-11(10-15-16(20)19-18(22)25-15)7-8-13(14)24-17(21)12-5-3-4-6-12/h7-10,12H,2-6H2,1H3,(H,19,20,22)/b15-10-
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n/an/a 1.40E+3n/an/an/an/an/an/a



INDUSTRY-ACADEMIC COOPERATION FOUNDATION CHOSUN UNIVERSITY

US Patent


Assay Description
To confirm whether the compounds according to the present disclosure have an effect of inhibiting 15-PGDH, the NADH, which appears at the wavelength ...


US Patent US10787425 (2020)

More data for this
Ligand-Target Pair
15-hydroxyprostaglandin dehydrogenase [NAD+]


(Homo sapiens (Human))
BDBM463935
PNG
(US10787425, Compound 61)
Show SMILES O=C(Oc1ccc(\C=C2/SC(=O)NC2=O)cc1)C1CC1
Show InChI InChI=1S/C14H11NO4S/c16-12-11(20-14(18)15-12)7-8-1-5-10(6-2-8)19-13(17)9-3-4-9/h1-2,5-7,9H,3-4H2,(H,15,16,18)/b11-7-
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n/an/a 1.41E+3n/an/an/an/an/an/a



INDUSTRY-ACADEMIC COOPERATION FOUNDATION CHOSUN UNIVERSITY

US Patent


Assay Description
To confirm whether the compounds according to the present disclosure have an effect of inhibiting 15-PGDH, the NADH, which appears at the wavelength ...


US Patent US10787425 (2020)

More data for this
Ligand-Target Pair
15-hydroxyprostaglandin dehydrogenase [NAD+]


(Homo sapiens (Human))
BDBM463920
PNG
(US10787425, Compound 47)
Show SMILES CCOc1cc(\C=C2/SC(=O)NC2=O)ccc1OC(=O)C1CCC1
Show InChI InChI=1S/C17H17NO5S/c1-2-22-13-8-10(9-14-15(19)18-17(21)24-14)6-7-12(13)23-16(20)11-4-3-5-11/h6-9,11H,2-5H2,1H3,(H,18,19,21)/b14-9-
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n/an/a 1.62E+3n/an/an/an/an/an/a



INDUSTRY-ACADEMIC COOPERATION FOUNDATION CHOSUN UNIVERSITY

US Patent


Assay Description
To confirm whether the compounds according to the present disclosure have an effect of inhibiting 15-PGDH, the NADH, which appears at the wavelength ...


US Patent US10787425 (2020)

More data for this
Ligand-Target Pair
15-hydroxyprostaglandin dehydrogenase [NAD+]


(Homo sapiens (Human))
BDBM463874
PNG
(US10787425, Compound 1)
Show SMILES Clc1cc(\C=C2/SC(=O)NC2=O)ccc1OC(=O)C1CC1
Show InChI InChI=1S/C14H10ClNO4S/c15-9-5-7(6-11-12(17)16-14(19)21-11)1-4-10(9)20-13(18)8-2-3-8/h1,4-6,8H,2-3H2,(H,16,17,19)/b11-6-
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n/an/a 2.09E+3n/an/an/an/an/an/a



INDUSTRY-ACADEMIC COOPERATION FOUNDATION CHOSUN UNIVERSITY

US Patent


Assay Description
To confirm whether the compounds according to the present disclosure have an effect of inhibiting 15-PGDH, the NADH, which appears at the wavelength ...


US Patent US10787425 (2020)

More data for this
Ligand-Target Pair
15-hydroxyprostaglandin dehydrogenase [NAD+]


(Homo sapiens (Human))
BDBM463919
PNG
(US10787425, Compound 46)
Show SMILES CCOc1cc(\C=C2/SC(=O)NC2=O)ccc1OC(=O)C1CC1
Show InChI InChI=1S/C16H15NO5S/c1-2-21-12-7-9(8-13-14(18)17-16(20)23-13)3-6-11(12)22-15(19)10-4-5-10/h3,6-8,10H,2,4-5H2,1H3,(H,17,18,20)/b13-8-
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n/an/a 2.17E+3n/an/an/an/an/an/a



INDUSTRY-ACADEMIC COOPERATION FOUNDATION CHOSUN UNIVERSITY

US Patent


Assay Description
To confirm whether the compounds according to the present disclosure have an effect of inhibiting 15-PGDH, the NADH, which appears at the wavelength ...


US Patent US10787425 (2020)

More data for this
Ligand-Target Pair
* indicates data uncertainty>20%