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Patent code US10793561

Compile Data Set for Download or QSAR
Found 2 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Adenosine receptor A1


(Homo sapiens (Human))
BDBM464678
PNG
(US10793561, Compound 1.14)
Show SMILES O=c1cc[nH]c2nc(-c3ccco3)c(cc12)-c1ccc2ncccc2c1
Show InChI InChI=1S/C21H13N3O2/c25-18-7-9-23-21-16(18)12-15(20(24-21)19-4-2-10-26-19)13-5-6-17-14(11-13)3-1-8-22-17/h1-12H,(H,23,24,25)
PDB

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UniProtKB/SwissProt

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PC cid
PC sid
UniChem
US Patent
n/an/a 33n/an/an/an/an/an/a



NUVATION BIO INC.

US Patent


Assay Description
For the adenosine A2A receptor radioligand binding assay, the following modifications were made to the general protocol. GF/C filters (Perkin Elmer, ...


US Patent US10793561 (2020)

More data for this
Ligand-Target Pair
Adenosine receptor A1


(Homo sapiens (Human))
BDBM464677
PNG
(US10793561, Compound 1.5)
Show SMILES COc1ccc2cc(ccc2n1)-c1cc2c(nc1-c1ccccc1)[nH]ccc2=O
Show InChI InChI=1S/C24H17N3O2/c1-29-22-10-8-17-13-16(7-9-20(17)26-22)18-14-19-21(28)11-12-25-24(19)27-23(18)15-5-3-2-4-6-15/h2-14H,1H3,(H,25,27,28)
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 181n/an/an/an/an/an/a



NUVATION BIO INC.

US Patent


Assay Description
For the adenosine A2A receptor radioligand binding assay, the following modifications were made to the general protocol. GF/C filters (Perkin Elmer, ...


US Patent US10793561 (2020)

More data for this
Ligand-Target Pair
* indicates data uncertainty>20%