BindingDB logo
myBDB logout

Patent code US10793564

Compile Data Set for Download or QSAR
Found 145 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Integrin alpha-V/alpha-5


(Homo sapiens (Human))
BDBM465246
PNG
(US10793564, Compound 35)
Show SMILES OC(=O)[C@H](CCN(CCCCc1ccc2CCCNc2n1)CCOC(F)F)Nc1ncnc2ccccc12
Show InChI InChI=1S/C27H34F2N6O3/c28-27(29)38-17-16-35(14-4-3-7-20-11-10-19-6-5-13-30-24(19)33-20)15-12-23(26(36)37)34-25-21-8-1-2-9-22(21)31-18-32-25/h1-2,8-11,18,23,27H,3-7,12-17H2,(H,30,33)(H,36,37)(H,31,32,34)/t23-/m0/s1
PDB

Reactome pathway

UniProtKB/SwissProt

antibodypedia
antibodypedia
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a<50n/an/an/an/an/an/a



PLIANT THERAPEUTICS, INC.

US Patent


Assay Description
Microplates were coated with recombinant human integrin αVβ6 (2 μg/mL) in PBS (100 μL/well 25 C., overnight). The coating soluti...


US Patent US10793564 (2020)

More data for this
Ligand-Target Pair
Integrin alpha-V/alpha-5


(Homo sapiens (Human))
BDBM465261
PNG
(US10793564, Compound 50)
Show SMILES OC(=O)[C@H](CCN(CCCCc1ccc2CCCNc2n1)CCOCC(F)F)Nc1ncnc2ccccc12
Show InChI InChI=1S/C28H36F2N6O3/c29-25(30)18-39-17-16-36(14-4-3-7-21-11-10-20-6-5-13-31-26(20)34-21)15-12-24(28(37)38)35-27-22-8-1-2-9-23(22)32-19-33-27/h1-2,8-11,19,24-25H,3-7,12-18H2,(H,31,34)(H,37,38)(H,32,33,35)/t24-/m0/s1
PDB

Reactome pathway

UniProtKB/SwissProt

antibodypedia
antibodypedia
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a<50n/an/an/an/an/an/a



PLIANT THERAPEUTICS, INC.

US Patent


Assay Description
Microplates were coated with recombinant human integrin αVβ6 (2 μg/mL) in PBS (100 μL/well 25 C., overnight). The coating soluti...


US Patent US10793564 (2020)

More data for this
Ligand-Target Pair
Integrin alpha-V/alpha-5


(Homo sapiens (Human))
BDBM465276
PNG
(US10793564, Compound 65)
Show SMILES CO[C@H](C)CN(CCCCc1ccc2CCCNc2n1)CC[C@H](Nc1nc(C)nc2cc(F)ccc12)C(O)=O
Show InChI InChI=1S/C29H39FN6O3/c1-19(39-3)18-36(15-5-4-8-23-11-9-21-7-6-14-31-27(21)34-23)16-13-25(29(37)38)35-28-24-12-10-22(30)17-26(24)32-20(2)33-28/h9-12,17,19,25H,4-8,13-16,18H2,1-3H3,(H,31,34)(H,37,38)(H,32,33,35)/t19-,25+/m1/s1
PDB

Reactome pathway

UniProtKB/SwissProt

antibodypedia
antibodypedia
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a<50n/an/an/an/an/an/a



PLIANT THERAPEUTICS, INC.

US Patent


Assay Description
Microplates were coated with recombinant human integrin αVβ6 (2 μg/mL) in PBS (100 μL/well 25 C., overnight). The coating soluti...


US Patent US10793564 (2020)

More data for this
Ligand-Target Pair
Integrin alpha-V/alpha-5


(Homo sapiens (Human))
BDBM465284
PNG
(US10793564, Compound 73)
Show SMILES CO[C@H](C)CN(CCCCc1ccc2CCCNc2n1)CC[C@H](Nc1ccnc(n1)-c1ccccc1)C(O)=O
Show InChI InChI=1S/C30H40N6O3/c1-22(39-2)21-36(19-7-6-12-25-14-13-24-11-8-17-31-28(24)33-25)20-16-26(30(37)38)34-27-15-18-32-29(35-27)23-9-4-3-5-10-23/h3-5,9-10,13-15,18,22,26H,6-8,11-12,16-17,19-21H2,1-2H3,(H,31,33)(H,37,38)(H,32,34,35)/t22-,26+/m1/s1
PDB

Reactome pathway

UniProtKB/SwissProt

antibodypedia
antibodypedia
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a<50n/an/an/an/an/an/a



PLIANT THERAPEUTICS, INC.

US Patent


Assay Description
Microplates were coated with recombinant human integrin αVβ6 (2 μg/mL) in PBS (100 μL/well 25 C., overnight). The coating soluti...


US Patent US10793564 (2020)

More data for this
Ligand-Target Pair
Integrin alpha-V/alpha-5


(Homo sapiens (Human))
BDBM465316
PNG
(US10793564, Compound 105)
Show SMILES COC[C@@H](F)CN(CCCCc1ccc2CCCNc2n1)CC[C@H](Nc1ncnc2n(C)ncc12)C(O)=O
Show InChI InChI=1S/C26H37FN8O3/c1-34-25-21(14-31-34)24(29-17-30-25)33-22(26(36)37)10-13-35(15-19(27)16-38-2)12-4-3-7-20-9-8-18-6-5-11-28-23(18)32-20/h8-9,14,17,19,22H,3-7,10-13,15-16H2,1-2H3,(H,28,32)(H,36,37)(H,29,30,33)/t19-,22-/m0/s1
PDB

Reactome pathway

UniProtKB/SwissProt

antibodypedia
antibodypedia
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a<50n/an/an/an/an/an/a



PLIANT THERAPEUTICS, INC.

US Patent


Assay Description
Microplates were coated with recombinant human integrin αVβ6 (2 μg/mL) in PBS (100 μL/well 25 C., overnight). The coating soluti...


US Patent US10793564 (2020)

More data for this
Ligand-Target Pair
Integrin alpha-V/alpha-5


(Homo sapiens (Human))
BDBM465334
PNG
(US10793564, Compound 124)
Show SMILES CO[C@H](C)CN(CCCCc1ccc2CCCNc2n1)CC[C@H](Nc1ncc(cn1)C1CC1)C(O)=O
Show InChI InChI=1S/C27H40N6O3/c1-19(36-2)18-33(14-4-3-7-23-11-10-21-6-5-13-28-25(21)31-23)15-12-24(26(34)35)32-27-29-16-22(17-30-27)20-8-9-20/h10-11,16-17,19-20,24H,3-9,12-15,18H2,1-2H3,(H,28,31)(H,34,35)(H,29,30,32)/t19-,24+/m1/s1
PDB

Reactome pathway

UniProtKB/SwissProt

antibodypedia
antibodypedia
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a<50n/an/an/an/an/an/a



PLIANT THERAPEUTICS, INC.

US Patent


Assay Description
Microplates were coated with recombinant human integrin αVβ6 (2 μg/mL) in PBS (100 μL/well 25 C., overnight). The coating soluti...


US Patent US10793564 (2020)

More data for this
Ligand-Target Pair
Integrin alpha-V/alpha-5


(Homo sapiens (Human))
BDBM465227
PNG
(US10793564, Compound 16)
Show SMILES COCCN(CCCCc1ccc2CCCNc2n1)CC[C@H](Nc1ncnc2cccnc12)C(O)=O
Show InChI InChI=1S/C26H35N7O3/c1-36-17-16-33(14-3-2-7-20-10-9-19-6-4-13-28-24(19)31-20)15-11-22(26(34)35)32-25-23-21(29-18-30-25)8-5-12-27-23/h5,8-10,12,18,22H,2-4,6-7,11,13-17H2,1H3,(H,28,31)(H,34,35)(H,29,30,32)/t22-/m0/s1
PDB

Reactome pathway

UniProtKB/SwissProt

antibodypedia
antibodypedia
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a<50n/an/an/an/an/an/a



PLIANT THERAPEUTICS, INC.

US Patent


Assay Description
Microplates were coated with recombinant human integrin αVβ6 (2 μg/mL) in PBS (100 μL/well 25 C., overnight). The coating soluti...


US Patent US10793564 (2020)

More data for this
Ligand-Target Pair
Integrin alpha-V/alpha-5


(Homo sapiens (Human))
BDBM465253
PNG
(US10793564, Compound 42)
Show SMILES Cc1nc(N[C@@H](CCN(CCCCc2ccc3CCCNc3n2)CCOC2CC2(F)F)C(O)=O)c2ccc(F)cc2n1
Show InChI InChI=1S/C30H37F3N6O3/c1-19-35-25-17-21(31)8-10-23(25)28(36-19)38-24(29(40)41)11-14-39(15-16-42-26-18-30(26,32)33)13-3-2-6-22-9-7-20-5-4-12-34-27(20)37-22/h7-10,17,24,26H,2-6,11-16,18H2,1H3,(H,34,37)(H,40,41)(H,35,36,38)/t24-,26?/m0/s1
PDB

Reactome pathway

UniProtKB/SwissProt

antibodypedia
antibodypedia
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a<50n/an/an/an/an/an/a



PLIANT THERAPEUTICS, INC.

US Patent


Assay Description
Microplates were coated with recombinant human integrin αVβ6 (2 μg/mL) in PBS (100 μL/well 25 C., overnight). The coating soluti...


US Patent US10793564 (2020)

More data for this
Ligand-Target Pair
Integrin alpha-V/alpha-5


(Homo sapiens (Human))
BDBM465254
PNG
(US10793564, Compound 43)
Show SMILES COc1cccc2c(N[C@@H](CCN(CCCF)CCCCc3ccc4CCCNc4n3)C(O)=O)ncnc12
Show InChI InChI=1S/C28H37FN6O3/c1-38-24-10-4-9-22-25(24)31-19-32-27(22)34-23(28(36)37)13-18-35(17-6-14-29)16-3-2-8-21-12-11-20-7-5-15-30-26(20)33-21/h4,9-12,19,23H,2-3,5-8,13-18H2,1H3,(H,30,33)(H,36,37)(H,31,32,34)/t23-/m0/s1
PDB

Reactome pathway

UniProtKB/SwissProt

antibodypedia
antibodypedia
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a<50n/an/an/an/an/an/a



PLIANT THERAPEUTICS, INC.

US Patent


Assay Description
Microplates were coated with recombinant human integrin αVβ6 (2 μg/mL) in PBS (100 μL/well 25 C., overnight). The coating soluti...


US Patent US10793564 (2020)

More data for this
Ligand-Target Pair
Integrin alpha-V/alpha-5


(Homo sapiens (Human))
BDBM465262
PNG
(US10793564, Compound 51)
Show SMILES OC(=O)[C@H](CCN(CCCCc1ccc2CCCNc2n1)CCOCC(F)(F)F)Nc1ncnc2cccnc12
Show InChI InChI=1S/C27H34F3N7O3/c28-27(29,30)17-40-16-15-37(13-2-1-6-20-9-8-19-5-3-12-32-24(19)35-20)14-10-22(26(38)39)36-25-23-21(33-18-34-25)7-4-11-31-23/h4,7-9,11,18,22H,1-3,5-6,10,12-17H2,(H,32,35)(H,38,39)(H,33,34,36)/t22-/m0/s1
PDB

Reactome pathway

UniProtKB/SwissProt

antibodypedia
antibodypedia
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a<50n/an/an/an/an/an/a



PLIANT THERAPEUTICS, INC.

US Patent


Assay Description
Microplates were coated with recombinant human integrin αVβ6 (2 μg/mL) in PBS (100 μL/well 25 C., overnight). The coating soluti...


US Patent US10793564 (2020)

More data for this
Ligand-Target Pair
Integrin alpha-V/alpha-5


(Homo sapiens (Human))
BDBM465269
PNG
(US10793564, Compound 58)
Show SMILES OC(=O)[C@H](CCN(CCCCc1ccc2CCCNc2n1)CCOc1cncc(F)c1)Nc1ncnc2ccccc12
Show InChI InChI=1S/C31H36FN7O3/c32-23-18-25(20-33-19-23)42-17-16-39(14-4-3-7-24-11-10-22-6-5-13-34-29(22)37-24)15-12-28(31(40)41)38-30-26-8-1-2-9-27(26)35-21-36-30/h1-2,8-11,18-21,28H,3-7,12-17H2,(H,34,37)(H,40,41)(H,35,36,38)/t28-/m0/s1
PDB

Reactome pathway

UniProtKB/SwissProt

antibodypedia
antibodypedia
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a<50n/an/an/an/an/an/a



PLIANT THERAPEUTICS, INC.

US Patent


Assay Description
Microplates were coated with recombinant human integrin αVβ6 (2 μg/mL) in PBS (100 μL/well 25 C., overnight). The coating soluti...


US Patent US10793564 (2020)

More data for this
Ligand-Target Pair
Integrin alpha-V/alpha-5


(Homo sapiens (Human))
BDBM465270
PNG
(US10793564, Compound 59)
Show SMILES Cc1ccc(OCCN(CCCCc2ccc3CCCNc3n2)CC[C@H](Nc2ncnc3ccccc23)C(O)=O)cn1
Show InChI InChI=1S/C32H39N7O3/c1-23-11-14-26(21-34-23)42-20-19-39(17-5-4-8-25-13-12-24-7-6-16-33-30(24)37-25)18-15-29(32(40)41)38-31-27-9-2-3-10-28(27)35-22-36-31/h2-3,9-14,21-22,29H,4-8,15-20H2,1H3,(H,33,37)(H,40,41)(H,35,36,38)/t29-/m0/s1
PDB

Reactome pathway

UniProtKB/SwissProt

antibodypedia
antibodypedia
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a<50n/an/an/an/an/an/a



PLIANT THERAPEUTICS, INC.

US Patent


Assay Description
Microplates were coated with recombinant human integrin αVβ6 (2 μg/mL) in PBS (100 μL/well 25 C., overnight). The coating soluti...


US Patent US10793564 (2020)

More data for this
Ligand-Target Pair
Integrin alpha-V/alpha-5


(Homo sapiens (Human))
BDBM465271
PNG
(US10793564, Compound 60)
Show SMILES OC(=O)[C@H](CCN(CCCCc1ccc2CCCNc2n1)CCOc1cncc(F)c1)Nc1ncnc2cccnc12
Show InChI InChI=1S/C30H35FN8O3/c31-22-17-24(19-32-18-22)42-16-15-39(13-2-1-6-23-9-8-21-5-3-12-34-28(21)37-23)14-10-26(30(40)41)38-29-27-25(35-20-36-29)7-4-11-33-27/h4,7-9,11,17-20,26H,1-3,5-6,10,12-16H2,(H,34,37)(H,40,41)(H,35,36,38)/t26-/m0/s1
PDB

Reactome pathway

UniProtKB/SwissProt

antibodypedia
antibodypedia
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a<50n/an/an/an/an/an/a



PLIANT THERAPEUTICS, INC.

US Patent


Assay Description
Microplates were coated with recombinant human integrin αVβ6 (2 μg/mL) in PBS (100 μL/well 25 C., overnight). The coating soluti...


US Patent US10793564 (2020)

More data for this
Ligand-Target Pair
Integrin alpha-V/alpha-5


(Homo sapiens (Human))
BDBM465273
PNG
(US10793564, Compound 62)
Show SMILES CO[C@H](C)CN(CCCCc1ccc2CCCNc2n1)CC[C@H](Nc1ncnc2ccccc12)C(O)=O
Show InChI InChI=1S/C28H38N6O3/c1-20(37-2)18-34(16-6-5-9-22-13-12-21-8-7-15-29-26(21)32-22)17-14-25(28(35)36)33-27-23-10-3-4-11-24(23)30-19-31-27/h3-4,10-13,19-20,25H,5-9,14-18H2,1-2H3,(H,29,32)(H,35,36)(H,30,31,33)/t20-,25+/m1/s1
PDB

Reactome pathway

UniProtKB/SwissProt

antibodypedia
antibodypedia
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a<50n/an/an/an/an/an/a



PLIANT THERAPEUTICS, INC.

US Patent


Assay Description
Microplates were coated with recombinant human integrin αVβ6 (2 μg/mL) in PBS (100 μL/well 25 C., overnight). The coating soluti...


US Patent US10793564 (2020)

More data for this
Ligand-Target Pair
Integrin alpha-V/alpha-5


(Homo sapiens (Human))
BDBM465283
PNG
(US10793564, Compound 72)
Show SMILES CO[C@H](C)CN(CCCCc1ccc2CCCNc2n1)CC[C@H](Nc1ccnc(n1)C(F)(F)F)C(O)=O
Show InChI InChI=1S/C25H35F3N6O3/c1-17(37-2)16-34(14-4-3-7-19-9-8-18-6-5-12-29-22(18)31-19)15-11-20(23(35)36)32-21-10-13-30-24(33-21)25(26,27)28/h8-10,13,17,20H,3-7,11-12,14-16H2,1-2H3,(H,29,31)(H,35,36)(H,30,32,33)/t17-,20+/m1/s1
PDB

Reactome pathway

UniProtKB/SwissProt

antibodypedia
antibodypedia
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a<50n/an/an/an/an/an/a



PLIANT THERAPEUTICS, INC.

US Patent


Assay Description
Microplates were coated with recombinant human integrin αVβ6 (2 μg/mL) in PBS (100 μL/well 25 C., overnight). The coating soluti...


US Patent US10793564 (2020)

More data for this
Ligand-Target Pair
Integrin alpha-V/alpha-5


(Homo sapiens (Human))
BDBM465285
PNG
(US10793564, Compound 74)
Show SMILES CO[C@H](C)CN(CCCCc1ccc2CCCNc2n1)CC[C@H](Nc1ncnc2n(C)ncc12)C(O)=O
Show InChI InChI=1S/C26H38N8O3/c1-18(37-3)16-34(13-5-4-8-20-10-9-19-7-6-12-27-23(19)31-20)14-11-22(26(35)36)32-24-21-15-30-33(2)25(21)29-17-28-24/h9-10,15,17-18,22H,4-8,11-14,16H2,1-3H3,(H,27,31)(H,35,36)(H,28,29,32)/t18-,22+/m1/s1
PDB

Reactome pathway

UniProtKB/SwissProt

antibodypedia
antibodypedia
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a<50n/an/an/an/an/an/a



PLIANT THERAPEUTICS, INC.

US Patent


Assay Description
Microplates were coated with recombinant human integrin αVβ6 (2 μg/mL) in PBS (100 μL/well 25 C., overnight). The coating soluti...


US Patent US10793564 (2020)

More data for this
Ligand-Target Pair
Integrin alpha-V/alpha-5


(Homo sapiens (Human))
BDBM465286
PNG
(US10793564, Compound 75)
Show SMILES OCCN(CCCCc1ccc2CCCNc2n1)CC[C@H](Nc1ncnc2ccccc12)C(O)=O
Show InChI InChI=1S/C26H34N6O3/c33-17-16-32(14-4-3-7-20-11-10-19-6-5-13-27-24(19)30-20)15-12-23(26(34)35)31-25-21-8-1-2-9-22(21)28-18-29-25/h1-2,8-11,18,23,33H,3-7,12-17H2,(H,27,30)(H,34,35)(H,28,29,31)/t23-/m0/s1
PDB

Reactome pathway

UniProtKB/SwissProt

antibodypedia
antibodypedia
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a<50n/an/an/an/an/an/a



PLIANT THERAPEUTICS, INC.

US Patent


Assay Description
Microplates were coated with recombinant human integrin αVβ6 (2 μg/mL) in PBS (100 μL/well 25 C., overnight). The coating soluti...


US Patent US10793564 (2020)

More data for this
Ligand-Target Pair
Integrin alpha-V/alpha-5


(Homo sapiens (Human))
BDBM465289
PNG
(US10793564, Compound 78)
Show SMILES CO[C@H](C)CN(CCCCc1ccc2CCCNc2n1)CC[C@H](Nc1ncc(F)cn1)C(O)=O
Show InChI InChI=1S/C24H35FN6O3/c1-17(34-2)16-31(13-10-21(23(32)33)30-24-27-14-19(25)15-28-24)12-4-3-7-20-9-8-18-6-5-11-26-22(18)29-20/h8-9,14-15,17,21H,3-7,10-13,16H2,1-2H3,(H,26,29)(H,32,33)(H,27,28,30)/t17-,21+/m1/s1
PDB

Reactome pathway

UniProtKB/SwissProt

antibodypedia
antibodypedia
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a<50n/an/an/an/an/an/a



PLIANT THERAPEUTICS, INC.

US Patent


Assay Description
Microplates were coated with recombinant human integrin αVβ6 (2 μg/mL) in PBS (100 μL/well 25 C., overnight). The coating soluti...


US Patent US10793564 (2020)

More data for this
Ligand-Target Pair
Integrin alpha-V/alpha-5


(Homo sapiens (Human))
BDBM465293
PNG
(US10793564, Compound 82)
Show SMILES Cn1ncc2c(N[C@@H](CCN(CCCCc3ccc4CCCNc4n3)CCOc3ccccc3)C(O)=O)ncnc12
Show InChI InChI=1S/C30H38N8O3/c1-37-29-25(20-34-37)28(32-21-33-29)36-26(30(39)40)14-17-38(18-19-41-24-10-3-2-4-11-24)16-6-5-9-23-13-12-22-8-7-15-31-27(22)35-23/h2-4,10-13,20-21,26H,5-9,14-19H2,1H3,(H,31,35)(H,39,40)(H,32,33,36)/t26-/m0/s1
PDB

Reactome pathway

UniProtKB/SwissProt

antibodypedia
antibodypedia
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a<50n/an/an/an/an/an/a



PLIANT THERAPEUTICS, INC.

US Patent


Assay Description
Microplates were coated with recombinant human integrin αVβ6 (2 μg/mL) in PBS (100 μL/well 25 C., overnight). The coating soluti...


US Patent US10793564 (2020)

More data for this
Ligand-Target Pair
Integrin alpha-V/alpha-5


(Homo sapiens (Human))
BDBM465302
PNG
(US10793564, Compound 91)
Show SMILES OC(=O)[C@H](CCN(CCCCc1ccc2CCCNc2n1)CCOc1ccccc1)Nc1cc(ncn1)-n1cccn1
Show InChI InChI=1S/C31H38N8O3/c40-31(41)27(37-28-22-29(34-23-33-28)39-18-7-16-35-39)14-19-38(20-21-42-26-10-2-1-3-11-26)17-5-4-9-25-13-12-24-8-6-15-32-30(24)36-25/h1-3,7,10-13,16,18,22-23,27H,4-6,8-9,14-15,17,19-21H2,(H,32,36)(H,40,41)(H,33,34,37)/t27-/m0/s1
PDB

Reactome pathway

UniProtKB/SwissProt

antibodypedia
antibodypedia
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a<50n/an/an/an/an/an/a



PLIANT THERAPEUTICS, INC.

US Patent


Assay Description
Microplates were coated with recombinant human integrin αVβ6 (2 μg/mL) in PBS (100 μL/well 25 C., overnight). The coating soluti...


US Patent US10793564 (2020)

More data for this
Ligand-Target Pair
Integrin alpha-V/alpha-5


(Homo sapiens (Human))
BDBM465324
PNG
(US10793564, Compound 114)
Show SMILES OC(=O)[C@H](CCN(CCCCc1ccc2CCCNc2n1)C1CC1)Nc1ncc(cn1)C(F)(F)F
Show InChI InChI=1S/C24H31F3N6O2/c25-24(26,27)17-14-29-23(30-15-17)32-20(22(34)35)10-13-33(19-8-9-19)12-2-1-5-18-7-6-16-4-3-11-28-21(16)31-18/h6-7,14-15,19-20H,1-5,8-13H2,(H,28,31)(H,34,35)(H,29,30,32)/t20-/m0/s1
PDB

Reactome pathway

UniProtKB/SwissProt

antibodypedia
antibodypedia
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a<50n/an/an/an/an/an/a



PLIANT THERAPEUTICS, INC.

US Patent


Assay Description
Microplates were coated with recombinant human integrin αVβ6 (2 μg/mL) in PBS (100 μL/well 25 C., overnight). The coating soluti...


US Patent US10793564 (2020)

More data for this
Ligand-Target Pair
Integrin alpha-V/alpha-5


(Homo sapiens (Human))
BDBM465327
PNG
(US10793564, Compound 117)
Show SMILES OC(=O)[C@H](CCN(CCCCc1ccc2CCCNc2n1)CCOc1ccccc1)Nc1ncc(cn1)C1CC1
Show InChI InChI=1S/C31H40N6O3/c38-30(39)28(36-31-33-21-25(22-34-31)23-11-12-23)15-18-37(19-20-40-27-9-2-1-3-10-27)17-5-4-8-26-14-13-24-7-6-16-32-29(24)35-26/h1-3,9-10,13-14,21-23,28H,4-8,11-12,15-20H2,(H,32,35)(H,38,39)(H,33,34,36)/t28-/m0/s1
PDB

Reactome pathway

UniProtKB/SwissProt

antibodypedia
antibodypedia
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a<50n/an/an/an/an/an/a



PLIANT THERAPEUTICS, INC.

US Patent


Assay Description
Microplates were coated with recombinant human integrin αVβ6 (2 μg/mL) in PBS (100 μL/well 25 C., overnight). The coating soluti...


US Patent US10793564 (2020)

More data for this
Ligand-Target Pair
Integrin alpha-V/alpha-5


(Homo sapiens (Human))
BDBM465218
PNG
(US10793564, Compound 7)
Show SMILES COCCN(CCCCc1ccc2CCCNc2n1)CC[C@H](Nc1ncnc2cc(F)ccc12)C(O)=O
Show InChI InChI=1S/C27H35FN6O3/c1-37-16-15-34(13-3-2-6-21-9-7-19-5-4-12-29-25(19)32-21)14-11-23(27(35)36)33-26-22-10-8-20(28)17-24(22)30-18-31-26/h7-10,17-18,23H,2-6,11-16H2,1H3,(H,29,32)(H,35,36)(H,30,31,33)/t23-/m0/s1
PDB

Reactome pathway

UniProtKB/SwissProt

antibodypedia
antibodypedia
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a<50n/an/an/an/an/an/a



PLIANT THERAPEUTICS, INC.

US Patent


Assay Description
Microplates were coated with recombinant human integrin αVβ6 (2 μg/mL) in PBS (100 μL/well 25 C., overnight). The coating soluti...


US Patent US10793564 (2020)

More data for this
Ligand-Target Pair
Integrin alpha-V/alpha-5


(Homo sapiens (Human))
BDBM465228
PNG
(US10793564, Compound 17)
Show SMILES COCCN(CCCCc1ccc2CCCNc2n1)CC[C@H](Nc1ncnc2cnccc12)C(O)=O
Show InChI InChI=1S/C26H35N7O3/c1-36-16-15-33(13-3-2-6-20-8-7-19-5-4-11-28-24(19)31-20)14-10-22(26(34)35)32-25-21-9-12-27-17-23(21)29-18-30-25/h7-9,12,17-18,22H,2-6,10-11,13-16H2,1H3,(H,28,31)(H,34,35)(H,29,30,32)/t22-/m0/s1
PDB

Reactome pathway

UniProtKB/SwissProt

antibodypedia
antibodypedia
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a<50n/an/an/an/an/an/a



PLIANT THERAPEUTICS, INC.

US Patent


Assay Description
Microplates were coated with recombinant human integrin αVβ6 (2 μg/mL) in PBS (100 μL/well 25 C., overnight). The coating soluti...


US Patent US10793564 (2020)

More data for this
Ligand-Target Pair
Integrin alpha-V/alpha-5


(Homo sapiens (Human))
BDBM465241
PNG
(US10793564, Compound 30)
Show SMILES OC(=O)[C@H](CCN(CCCF)CCCCc1ccc2CCCNc2n1)Nc1ncnc2ccccc12
Show InChI InChI=1S/C27H35FN6O2/c28-14-6-17-34(16-4-3-8-21-12-11-20-7-5-15-29-25(20)32-21)18-13-24(27(35)36)33-26-22-9-1-2-10-23(22)30-19-31-26/h1-2,9-12,19,24H,3-8,13-18H2,(H,29,32)(H,35,36)(H,30,31,33)/t24-/m0/s1
PDB

Reactome pathway

UniProtKB/SwissProt

antibodypedia
antibodypedia
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a<50n/an/an/an/an/an/a



PLIANT THERAPEUTICS, INC.

US Patent


Assay Description
Microplates were coated with recombinant human integrin αVβ6 (2 μg/mL) in PBS (100 μL/well 25 C., overnight). The coating soluti...


US Patent US10793564 (2020)

More data for this
Ligand-Target Pair
Integrin alpha-V/alpha-5


(Homo sapiens (Human))
BDBM465250
PNG
(US10793564, Compound 39)
Show SMILES OC(=O)[C@H](CCN(CCCCc1ccc2CCCNc2n1)CCOCC(F)(F)F)Nc1ncnc2ccccc12
Show InChI InChI=1S/C28H35F3N6O3/c29-28(30,31)18-40-17-16-37(14-4-3-7-21-11-10-20-6-5-13-32-25(20)35-21)15-12-24(27(38)39)36-26-22-8-1-2-9-23(22)33-19-34-26/h1-2,8-11,19,24H,3-7,12-18H2,(H,32,35)(H,38,39)(H,33,34,36)/t24-/m0/s1
PDB

Reactome pathway

UniProtKB/SwissProt

antibodypedia
antibodypedia
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a<50n/an/an/an/an/an/a



PLIANT THERAPEUTICS, INC.

US Patent


Assay Description
Microplates were coated with recombinant human integrin αVβ6 (2 μg/mL) in PBS (100 μL/well 25 C., overnight). The coating soluti...


US Patent US10793564 (2020)

More data for this
Ligand-Target Pair
Integrin alpha-V/alpha-5


(Homo sapiens (Human))
BDBM465255
PNG
(US10793564, Compound 44)
Show SMILES COCCN(CCCCc1ccc2CCCNc2n1)CC[C@H](Nc1cc(ncn1)-n1cccn1)C(O)=O
Show InChI InChI=1S/C26H36N8O3/c1-37-17-16-33(13-3-2-7-21-9-8-20-6-4-11-27-25(20)31-21)15-10-22(26(35)36)32-23-18-24(29-19-28-23)34-14-5-12-30-34/h5,8-9,12,14,18-19,22H,2-4,6-7,10-11,13,15-17H2,1H3,(H,27,31)(H,35,36)(H,28,29,32)/t22-/m0/s1
PDB

Reactome pathway

UniProtKB/SwissProt

antibodypedia
antibodypedia
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a<50n/an/an/an/an/an/a



PLIANT THERAPEUTICS, INC.

US Patent


Assay Description
Microplates were coated with recombinant human integrin αVβ6 (2 μg/mL) in PBS (100 μL/well 25 C., overnight). The coating soluti...


US Patent US10793564 (2020)

More data for this
Ligand-Target Pair
Integrin alpha-V/alpha-5


(Homo sapiens (Human))
BDBM465256
PNG
(US10793564, Compound 45)
Show SMILES Cc1cc(C)n(CCN(CCCCc2ccc3CCCNc3n2)CC[C@H](Nc2ncnc3ccccc23)C(O)=O)n1
Show InChI InChI=1S/C31H40N8O2/c1-22-20-23(2)39(37-22)19-18-38(16-6-5-9-25-13-12-24-8-7-15-32-29(24)35-25)17-14-28(31(40)41)36-30-26-10-3-4-11-27(26)33-21-34-30/h3-4,10-13,20-21,28H,5-9,14-19H2,1-2H3,(H,32,35)(H,40,41)(H,33,34,36)/t28-/m0/s1
PDB

Reactome pathway

UniProtKB/SwissProt

antibodypedia
antibodypedia
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a<50n/an/an/an/an/an/a



PLIANT THERAPEUTICS, INC.

US Patent


Assay Description
Microplates were coated with recombinant human integrin αVβ6 (2 μg/mL) in PBS (100 μL/well 25 C., overnight). The coating soluti...


US Patent US10793564 (2020)

More data for this
Ligand-Target Pair
Integrin alpha-V/alpha-5


(Homo sapiens (Human))
BDBM465272
PNG
(US10793564, Compound 61)
Show SMILES Cc1nc(N[C@@H](CCN(CCCCc2ccc3CCCNc3n2)CCOc2cncc(F)c2)C(O)=O)c2ccc(F)cc2n1
Show InChI InChI=1S/C32H37F2N7O3/c1-21-37-29-18-23(33)8-10-27(29)31(38-21)40-28(32(42)43)11-14-41(15-16-44-26-17-24(34)19-35-20-26)13-3-2-6-25-9-7-22-5-4-12-36-30(22)39-25/h7-10,17-20,28H,2-6,11-16H2,1H3,(H,36,39)(H,42,43)(H,37,38,40)/t28-/m0/s1
PDB

Reactome pathway

UniProtKB/SwissProt

antibodypedia
antibodypedia
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a<50n/an/an/an/an/an/a



PLIANT THERAPEUTICS, INC.

US Patent


Assay Description
Microplates were coated with recombinant human integrin αVβ6 (2 μg/mL) in PBS (100 μL/well 25 C., overnight). The coating soluti...


US Patent US10793564 (2020)

More data for this
Ligand-Target Pair
Integrin alpha-V/alpha-5


(Homo sapiens (Human))
BDBM465291
PNG
(US10793564, Compound 80)
Show SMILES CO[C@H](C)CN(CCCCc1ccc2CCCNc2n1)CC[C@H](Nc1cc(ncn1)-c1ccccc1)C(O)=O
Show InChI InChI=1S/C30H40N6O3/c1-22(39-2)20-36(17-7-6-12-25-14-13-24-11-8-16-31-29(24)34-25)18-15-26(30(37)38)35-28-19-27(32-21-33-28)23-9-4-3-5-10-23/h3-5,9-10,13-14,19,21-22,26H,6-8,11-12,15-18,20H2,1-2H3,(H,31,34)(H,37,38)(H,32,33,35)/t22-,26+/m1/s1
PDB

Reactome pathway

UniProtKB/SwissProt

antibodypedia
antibodypedia
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a<50n/an/an/an/an/an/a



PLIANT THERAPEUTICS, INC.

US Patent


Assay Description
Microplates were coated with recombinant human integrin αVβ6 (2 μg/mL) in PBS (100 μL/well 25 C., overnight). The coating soluti...


US Patent US10793564 (2020)

More data for this
Ligand-Target Pair
Integrin alpha-V/alpha-5


(Homo sapiens (Human))
BDBM465292
PNG
(US10793564, Compound 81)
Show SMILES C[C@@H](O)CN(CCCCc1ccc2CCCNc2n1)CC[C@H](Nc1ncncc1-c1ccccc1)C(O)=O
Show InChI InChI=1S/C29H38N6O3/c1-21(36)19-35(16-6-5-11-24-13-12-23-10-7-15-31-27(23)33-24)17-14-26(29(37)38)34-28-25(18-30-20-32-28)22-8-3-2-4-9-22/h2-4,8-9,12-13,18,20-21,26,36H,5-7,10-11,14-17,19H2,1H3,(H,31,33)(H,37,38)(H,30,32,34)/t21-,26+/m1/s1
PDB

Reactome pathway

UniProtKB/SwissProt

antibodypedia
antibodypedia
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a<50n/an/an/an/an/an/a



PLIANT THERAPEUTICS, INC.

US Patent


Assay Description
Microplates were coated with recombinant human integrin αVβ6 (2 μg/mL) in PBS (100 μL/well 25 C., overnight). The coating soluti...


US Patent US10793564 (2020)

More data for this
Ligand-Target Pair
Integrin alpha-V/alpha-5


(Homo sapiens (Human))
BDBM465346
PNG
(US10793564, Compound 136)
Show SMILES Cn1ncc2c(N[C@@H](CCN(CCCF)CCCCc3ccc4CCCNc4n3)C(O)=O)ncnc12
Show InChI InChI=1S/C25H35FN8O2/c1-33-24-20(16-30-33)23(28-17-29-24)32-21(25(35)36)10-15-34(14-5-11-26)13-3-2-7-19-9-8-18-6-4-12-27-22(18)31-19/h8-9,16-17,21H,2-7,10-15H2,1H3,(H,27,31)(H,35,36)(H,28,29,32)/t21-/m0/s1
PDB

Reactome pathway

UniProtKB/SwissProt

antibodypedia
antibodypedia
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a<50n/an/an/an/an/an/a



PLIANT THERAPEUTICS, INC.

US Patent


Assay Description
Microplates were coated with recombinant human integrin αVβ6 (2 μg/mL) in PBS (100 μL/well 25 C., overnight). The coating soluti...


US Patent US10793564 (2020)

More data for this
Ligand-Target Pair
Integrin alpha-V/alpha-5


(Homo sapiens (Human))
BDBM465232
PNG
(US10793564, Compound 21)
Show SMILES COCCN(CCCCc1ccc2CCCNc2n1)CC[C@H](Nc1ncnc2cc(F)c(F)cc12)C(O)=O
Show InChI InChI=1S/C27H34F2N6O3/c1-38-14-13-35(11-3-2-6-19-8-7-18-5-4-10-30-25(18)33-19)12-9-23(27(36)37)34-26-20-15-21(28)22(29)16-24(20)31-17-32-26/h7-8,15-17,23H,2-6,9-14H2,1H3,(H,30,33)(H,36,37)(H,31,32,34)/t23-/m0/s1
PDB

Reactome pathway

UniProtKB/SwissProt

antibodypedia
antibodypedia
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a<50n/an/an/an/an/an/a



PLIANT THERAPEUTICS, INC.

US Patent


Assay Description
Microplates were coated with recombinant human integrin αVβ6 (2 μg/mL) in PBS (100 μL/well 25 C., overnight). The coating soluti...


US Patent US10793564 (2020)

More data for this
Ligand-Target Pair
Integrin alpha-V/alpha-5


(Homo sapiens (Human))
BDBM465237
PNG
(US10793564, Compound 26)
Show SMILES COCCN(CCCCc1ccc2CCCNc2n1)CC[C@H](Nc1cc(C)nc(n1)C(F)(F)F)C(O)=O
Show InChI InChI=1S/C25H35F3N6O3/c1-17-16-21(33-24(30-17)25(26,27)28)32-20(23(35)36)10-13-34(14-15-37-2)12-4-3-7-19-9-8-18-6-5-11-29-22(18)31-19/h8-9,16,20H,3-7,10-15H2,1-2H3,(H,29,31)(H,35,36)(H,30,32,33)/t20-/m0/s1
PDB

Reactome pathway

UniProtKB/SwissProt

antibodypedia
antibodypedia
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a<50n/an/an/an/an/an/a



PLIANT THERAPEUTICS, INC.

US Patent


Assay Description
Microplates were coated with recombinant human integrin αVβ6 (2 μg/mL) in PBS (100 μL/well 25 C., overnight). The coating soluti...


US Patent US10793564 (2020)

More data for this
Ligand-Target Pair
Integrin alpha-V/alpha-5


(Homo sapiens (Human))
BDBM465259
PNG
(US10793564, Compound 48)
Show SMILES OC(=O)[C@H](CCN(CCCCc1ccc2CCCNc2n1)CCOc1ccccn1)Nc1ncnc2c(Cl)cccc12
Show InChI InChI=1S/C31H36ClN7O3/c32-25-10-5-9-24-28(25)35-21-36-30(24)38-26(31(40)41)14-18-39(19-20-42-27-11-1-3-15-33-27)17-4-2-8-23-13-12-22-7-6-16-34-29(22)37-23/h1,3,5,9-13,15,21,26H,2,4,6-8,14,16-20H2,(H,34,37)(H,40,41)(H,35,36,38)/t26-/m0/s1
PDB

Reactome pathway

UniProtKB/SwissProt

antibodypedia
antibodypedia
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a<50n/an/an/an/an/an/a



PLIANT THERAPEUTICS, INC.

US Patent


Assay Description
Microplates were coated with recombinant human integrin αVβ6 (2 μg/mL) in PBS (100 μL/well 25 C., overnight). The coating soluti...


US Patent US10793564 (2020)

More data for this
Ligand-Target Pair
Integrin alpha-V/alpha-5


(Homo sapiens (Human))
BDBM465333
PNG
(US10793564, Compound 123)
Show SMILES Cn1ncc2c(N[C@@H](CCN(CCCCc3ccc4CCCNc4n3)CCOc3ccc(F)cc3)C(O)=O)ncnc12
Show InChI InChI=1S/C30H37FN8O3/c1-38-29-25(19-35-38)28(33-20-34-29)37-26(30(40)41)13-16-39(17-18-42-24-11-8-22(31)9-12-24)15-3-2-6-23-10-7-21-5-4-14-32-27(21)36-23/h7-12,19-20,26H,2-6,13-18H2,1H3,(H,32,36)(H,40,41)(H,33,34,37)/t26-/m0/s1
PDB

Reactome pathway

UniProtKB/SwissProt

antibodypedia
antibodypedia
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a<50n/an/an/an/an/an/a



PLIANT THERAPEUTICS, INC.

US Patent


Assay Description
Microplates were coated with recombinant human integrin αVβ6 (2 μg/mL) in PBS (100 μL/well 25 C., overnight). The coating soluti...


US Patent US10793564 (2020)

More data for this
Ligand-Target Pair
Integrin alpha-V/alpha-5


(Homo sapiens (Human))
BDBM465347
PNG
(US10793564, Compound 137)
Show SMILES OC(=O)[C@H](CCN(CCCF)CCCCc1ccc2CCCNc2n1)Nc1ncc(cn1)C(F)(F)F
Show InChI InChI=1S/C24H32F4N6O2/c25-10-4-13-34(12-2-1-6-19-8-7-17-5-3-11-29-21(17)32-19)14-9-20(22(35)36)33-23-30-15-18(16-31-23)24(26,27)28/h7-8,15-16,20H,1-6,9-14H2,(H,29,32)(H,35,36)(H,30,31,33)/t20-/m0/s1
PDB

Reactome pathway

UniProtKB/SwissProt

antibodypedia
antibodypedia
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a<50n/an/an/an/an/an/a



PLIANT THERAPEUTICS, INC.

US Patent


Assay Description
Microplates were coated with recombinant human integrin αVβ6 (2 μg/mL) in PBS (100 μL/well 25 C., overnight). The coating soluti...


US Patent US10793564 (2020)

More data for this
Ligand-Target Pair
Integrin alpha-V/alpha-5


(Homo sapiens (Human))
BDBM465355
PNG
((S)-4-((2-(dimethylamino)-2-oxoethyl) (4-(5,6,7,8-...)
Show SMILES CN(C)C(=O)CN(CCCCc1ccc2CCCNc2n1)CC[C@H](Nc1ccnc(n1)C(F)(F)F)C(O)=O
Show InChI InChI=1S/C25H34F3N7O3/c1-34(2)21(36)16-35(14-4-3-7-18-9-8-17-6-5-12-29-22(17)31-18)15-11-19(23(37)38)32-20-10-13-30-24(33-20)25(26,27)28/h8-10,13,19H,3-7,11-12,14-16H2,1-2H3,(H,29,31)(H,37,38)(H,30,32,33)/t19-/m0/s1
PDB

Reactome pathway

UniProtKB/SwissProt

antibodypedia
antibodypedia
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a<50n/an/an/an/an/an/a



PLIANT THERAPEUTICS, INC.

US Patent


Assay Description
Microplates were coated with recombinant human integrin αVβ6 (2 μg/mL) in PBS (100 μL/well 25 C., overnight). The coating soluti...


US Patent US10793564 (2020)

More data for this
Ligand-Target Pair
Integrin alpha-V/alpha-5


(Homo sapiens (Human))
BDBM465226
PNG
(US10793564, Compound 15)
Show SMILES COCCN(CCCCc1ccc2CCCNc2n1)CC[C@H](Nc1ncnc2c(cccc12)C(F)(F)F)C(O)=O
Show InChI InChI=1S/C28H35F3N6O3/c1-40-17-16-37(14-3-2-7-20-11-10-19-6-5-13-32-25(19)35-20)15-12-23(27(38)39)36-26-21-8-4-9-22(28(29,30)31)24(21)33-18-34-26/h4,8-11,18,23H,2-3,5-7,12-17H2,1H3,(H,32,35)(H,38,39)(H,33,34,36)/t23-/m0/s1
PDB

Reactome pathway

UniProtKB/SwissProt

antibodypedia
antibodypedia
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a<50n/an/an/an/an/an/a



PLIANT THERAPEUTICS, INC.

US Patent


Assay Description
Microplates were coated with recombinant human integrin αVβ6 (2 μg/mL) in PBS (100 μL/well 25 C., overnight). The coating soluti...


US Patent US10793564 (2020)

More data for this
Ligand-Target Pair
Integrin alpha-V/alpha-5


(Homo sapiens (Human))
BDBM465231
PNG
(US10793564, Compound 20)
Show SMILES COCCN(CCCCc1ccc2CCCNc2n1)CC[C@H](Nc1ncnc2c(F)cccc12)C(O)=O
Show InChI InChI=1S/C27H35FN6O3/c1-37-17-16-34(14-3-2-7-20-11-10-19-6-5-13-29-25(19)32-20)15-12-23(27(35)36)33-26-21-8-4-9-22(28)24(21)30-18-31-26/h4,8-11,18,23H,2-3,5-7,12-17H2,1H3,(H,29,32)(H,35,36)(H,30,31,33)/t23-/m0/s1
PDB

Reactome pathway

UniProtKB/SwissProt

antibodypedia
antibodypedia
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a<50n/an/an/an/an/an/a



PLIANT THERAPEUTICS, INC.

US Patent


Assay Description
Microplates were coated with recombinant human integrin αVβ6 (2 μg/mL) in PBS (100 μL/well 25 C., overnight). The coating soluti...


US Patent US10793564 (2020)

More data for this
Ligand-Target Pair
Integrin alpha-V/alpha-5


(Homo sapiens (Human))
BDBM465240
PNG
(US10793564, Compound 29)
Show SMILES OC(=O)[C@H](CCN(CCCCc1ccc2CCCNc2n1)CCC(F)F)Nc1ncnc2ccccc12
Show InChI InChI=1S/C27H34F2N6O2/c28-24(29)13-17-35(15-4-3-7-20-11-10-19-6-5-14-30-25(19)33-20)16-12-23(27(36)37)34-26-21-8-1-2-9-22(21)31-18-32-26/h1-2,8-11,18,23-24H,3-7,12-17H2,(H,30,33)(H,36,37)(H,31,32,34)/t23-/m0/s1
PDB

Reactome pathway

UniProtKB/SwissProt

antibodypedia
antibodypedia
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a<50n/an/an/an/an/an/a



PLIANT THERAPEUTICS, INC.

US Patent


Assay Description
Microplates were coated with recombinant human integrin αVβ6 (2 μg/mL) in PBS (100 μL/well 25 C., overnight). The coating soluti...


US Patent US10793564 (2020)

More data for this
Ligand-Target Pair
Integrin alpha-V/alpha-5


(Homo sapiens (Human))
BDBM465252
PNG
(US10793564, Compound 41)
Show SMILES COc1ccc2c(N[C@@H](CCN(CCCF)CCCCc3ccc4CCCNc4n3)C(O)=O)ncnc2c1
Show InChI InChI=1S/C28H37FN6O3/c1-38-22-10-11-23-25(18-22)31-19-32-27(23)34-24(28(36)37)12-17-35(16-5-13-29)15-3-2-7-21-9-8-20-6-4-14-30-26(20)33-21/h8-11,18-19,24H,2-7,12-17H2,1H3,(H,30,33)(H,36,37)(H,31,32,34)/t24-/m0/s1
PDB

Reactome pathway

UniProtKB/SwissProt

antibodypedia
antibodypedia
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a<50n/an/an/an/an/an/a



PLIANT THERAPEUTICS, INC.

US Patent


Assay Description
Microplates were coated with recombinant human integrin αVβ6 (2 μg/mL) in PBS (100 μL/well 25 C., overnight). The coating soluti...


US Patent US10793564 (2020)

More data for this
Ligand-Target Pair
Integrin alpha-V/alpha-5


(Homo sapiens (Human))
BDBM465263
PNG
(US10793564, Compound 52)
Show SMILES Cc1ncccc1OCCN(CCCCc1ccc2CCCNc2n1)CC[C@H](Nc1ncnc2ccccc12)C(O)=O
Show InChI InChI=1S/C32H39N7O3/c1-23-29(12-7-16-33-23)42-21-20-39(18-5-4-9-25-14-13-24-8-6-17-34-30(24)37-25)19-15-28(32(40)41)38-31-26-10-2-3-11-27(26)35-22-36-31/h2-3,7,10-14,16,22,28H,4-6,8-9,15,17-21H2,1H3,(H,34,37)(H,40,41)(H,35,36,38)/t28-/m0/s1
PDB

Reactome pathway

UniProtKB/SwissProt

antibodypedia
antibodypedia
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a<50n/an/an/an/an/an/a



PLIANT THERAPEUTICS, INC.

US Patent


Assay Description
Microplates were coated with recombinant human integrin αVβ6 (2 μg/mL) in PBS (100 μL/well 25 C., overnight). The coating soluti...


US Patent US10793564 (2020)

More data for this
Ligand-Target Pair
Integrin alpha-V/alpha-5


(Homo sapiens (Human))
BDBM465264
PNG
(US10793564, Compound 53)
Show SMILES Cc1nc(N[C@@H](CCN(CCCCc2ccc3CCCNc3n2)CCOc2cccnc2C)C(O)=O)c2ccc(F)cc2n1
Show InChI InChI=1S/C33H40FN7O3/c1-22-30(9-6-15-35-22)44-20-19-41(17-4-3-8-26-12-10-24-7-5-16-36-31(24)39-26)18-14-28(33(42)43)40-32-27-13-11-25(34)21-29(27)37-23(2)38-32/h6,9-13,15,21,28H,3-5,7-8,14,16-20H2,1-2H3,(H,36,39)(H,42,43)(H,37,38,40)/t28-/m0/s1
PDB

Reactome pathway

UniProtKB/SwissProt

antibodypedia
antibodypedia
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a<50n/an/an/an/an/an/a



PLIANT THERAPEUTICS, INC.

US Patent


Assay Description
Microplates were coated with recombinant human integrin αVβ6 (2 μg/mL) in PBS (100 μL/well 25 C., overnight). The coating soluti...


US Patent US10793564 (2020)

More data for this
Ligand-Target Pair
Integrin alpha-V/alpha-5


(Homo sapiens (Human))
BDBM465216
PNG
(US10793564, Compound 5 | US10793564, Compound 55)
Show SMILES COCCN(CCCCc1ccc2CCCNc2n1)CC[C@H](Nc1ncnc2ccccc12)C(O)=O
Show InChI InChI=1S/C27H36N6O3/c1-36-18-17-33(15-5-4-8-21-12-11-20-7-6-14-28-25(20)31-21)16-13-24(27(34)35)32-26-22-9-2-3-10-23(22)29-19-30-26/h2-3,9-12,19,24H,4-8,13-18H2,1H3,(H,28,31)(H,34,35)(H,29,30,32)/t24-/m0/s1
PDB

Reactome pathway

UniProtKB/SwissProt

antibodypedia
antibodypedia
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a<50n/an/an/an/an/an/a



PLIANT THERAPEUTICS, INC.

US Patent


Assay Description
Microplates were coated with recombinant human integrin αVβ6 (2 μg/mL) in PBS (100 μL/well 25 C., overnight). The coating soluti...


US Patent US10793564 (2020)

More data for this
Ligand-Target Pair
Integrin alpha-V/alpha-5


(Homo sapiens (Human))
BDBM465268
PNG
(US10793564, Compound 57)
Show SMILES Cc1ccc(OCCN(CCCCc2ccc3CCCNc3n2)CC[C@H](Nc2ncnc3cccnc23)C(O)=O)cn1
Show InChI InChI=1S/C31H38N8O3/c1-22-9-12-25(20-34-22)42-19-18-39(16-3-2-7-24-11-10-23-6-4-15-33-29(23)37-24)17-13-27(31(40)41)38-30-28-26(35-21-36-30)8-5-14-32-28/h5,8-12,14,20-21,27H,2-4,6-7,13,15-19H2,1H3,(H,33,37)(H,40,41)(H,35,36,38)/t27-/m0/s1
PDB

Reactome pathway

UniProtKB/SwissProt

antibodypedia
antibodypedia
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a<50n/an/an/an/an/an/a



PLIANT THERAPEUTICS, INC.

US Patent


Assay Description
Microplates were coated with recombinant human integrin αVβ6 (2 μg/mL) in PBS (100 μL/well 25 C., overnight). The coating soluti...


US Patent US10793564 (2020)

More data for this
Ligand-Target Pair
Integrin alpha-V/alpha-5


(Homo sapiens (Human))
BDBM465274
PNG
(US10793564, Compound 63)
Show SMILES CC(=O)NCCN(CCCCc1ccc2CCCNc2n1)CC[C@H](Nc1ncnc2ccccc12)C(O)=O
Show InChI InChI=1S/C28H37N7O3/c1-20(36)29-15-18-35(16-5-4-8-22-12-11-21-7-6-14-30-26(21)33-22)17-13-25(28(37)38)34-27-23-9-2-3-10-24(23)31-19-32-27/h2-3,9-12,19,25H,4-8,13-18H2,1H3,(H,29,36)(H,30,33)(H,37,38)(H,31,32,34)/t25-/m0/s1
PDB

Reactome pathway

UniProtKB/SwissProt

antibodypedia
antibodypedia
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a<50n/an/an/an/an/an/a



PLIANT THERAPEUTICS, INC.

US Patent


Assay Description
Microplates were coated with recombinant human integrin αVβ6 (2 μg/mL) in PBS (100 μL/well 25 C., overnight). The coating soluti...


US Patent US10793564 (2020)

More data for this
Ligand-Target Pair
Integrin alpha-V/alpha-5


(Homo sapiens (Human))
BDBM465275
PNG
(US10793564, Compound 64)
Show SMILES CN(C)C(=O)CN(CCCCc1ccc2CCCNc2n1)CC[C@H](Nc1ncnc2ccccc12)C(O)=O
Show InChI InChI=1S/C28H37N7O3/c1-34(2)25(36)18-35(16-6-5-9-21-13-12-20-8-7-15-29-26(20)32-21)17-14-24(28(37)38)33-27-22-10-3-4-11-23(22)30-19-31-27/h3-4,10-13,19,24H,5-9,14-18H2,1-2H3,(H,29,32)(H,37,38)(H,30,31,33)/t24-/m0/s1
PDB

Reactome pathway

UniProtKB/SwissProt

antibodypedia
antibodypedia
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a<50n/an/an/an/an/an/a



PLIANT THERAPEUTICS, INC.

US Patent


Assay Description
Microplates were coated with recombinant human integrin αVβ6 (2 μg/mL) in PBS (100 μL/well 25 C., overnight). The coating soluti...


US Patent US10793564 (2020)

More data for this
Ligand-Target Pair
Integrin alpha-V/alpha-5


(Homo sapiens (Human))
BDBM465279
PNG
(US10793564, Compound 68)
Show SMILES CO[C@H](C)CN(CCCCc1ccc2CCCNc2n1)CC[C@H](Nc1ncc(cn1)C#N)C(O)=O
Show InChI InChI=1S/C25H35N7O3/c1-18(35-2)17-32(12-4-3-7-21-9-8-20-6-5-11-27-23(20)30-21)13-10-22(24(33)34)31-25-28-15-19(14-26)16-29-25/h8-9,15-16,18,22H,3-7,10-13,17H2,1-2H3,(H,27,30)(H,33,34)(H,28,29,31)/t18-,22+/m1/s1
PDB

Reactome pathway

UniProtKB/SwissProt

antibodypedia
antibodypedia
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a<50n/an/an/an/an/an/a



PLIANT THERAPEUTICS, INC.

US Patent


Assay Description
Microplates were coated with recombinant human integrin αVβ6 (2 μg/mL) in PBS (100 μL/well 25 C., overnight). The coating soluti...


US Patent US10793564 (2020)

More data for this
Ligand-Target Pair
Integrin alpha-V/alpha-5


(Homo sapiens (Human))
BDBM465281
PNG
(US10793564, Compound 70)
Show SMILES CO[C@H](C)CN(CCCCc1ccc2CCCNc2n1)CC[C@H](Nc1ncc(Br)cn1)C(O)=O
Show InChI InChI=1S/C24H35BrN6O3/c1-17(34-2)16-31(13-10-21(23(32)33)30-24-27-14-19(25)15-28-24)12-4-3-7-20-9-8-18-6-5-11-26-22(18)29-20/h8-9,14-15,17,21H,3-7,10-13,16H2,1-2H3,(H,26,29)(H,32,33)(H,27,28,30)/t17-,21+/m1/s1
PDB

Reactome pathway

UniProtKB/SwissProt

antibodypedia
antibodypedia
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a<50n/an/an/an/an/an/a



PLIANT THERAPEUTICS, INC.

US Patent


Assay Description
Microplates were coated with recombinant human integrin αVβ6 (2 μg/mL) in PBS (100 μL/well 25 C., overnight). The coating soluti...


US Patent US10793564 (2020)

More data for this
Ligand-Target Pair
Integrin alpha-V/alpha-5


(Homo sapiens (Human))
BDBM465282
PNG
(US10793564, Compound 71)
Show SMILES CO[C@H](C)CN(CCCCc1ccc2CCCNc2n1)CC[C@H](Nc1ncnc2[nH]ncc12)C(O)=O
Show InChI InChI=1S/C25H36N8O3/c1-17(36-2)15-33(12-4-3-7-19-9-8-18-6-5-11-26-22(18)30-19)13-10-21(25(34)35)31-23-20-14-29-32-24(20)28-16-27-23/h8-9,14,16-17,21H,3-7,10-13,15H2,1-2H3,(H,26,30)(H,34,35)(H2,27,28,29,31,32)/t17-,21+/m1/s1
PDB

Reactome pathway

UniProtKB/SwissProt

antibodypedia
antibodypedia
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a<50n/an/an/an/an/an/a



PLIANT THERAPEUTICS, INC.

US Patent


Assay Description
Microplates were coated with recombinant human integrin αVβ6 (2 μg/mL) in PBS (100 μL/well 25 C., overnight). The coating soluti...


US Patent US10793564 (2020)

More data for this
Ligand-Target Pair
Integrin alpha-V/alpha-5


(Homo sapiens (Human))
BDBM465287
PNG
(US10793564, Compound 76)
Show SMILES CO[C@H](C)CN(CCCCc1ccc2CCCNc2n1)CC[C@H](Nc1nccnc1C#N)C(O)=O
Show InChI InChI=1S/C25H35N7O3/c1-18(35-2)17-32(14-4-3-7-20-9-8-19-6-5-11-28-23(19)30-20)15-10-21(25(33)34)31-24-22(16-26)27-12-13-29-24/h8-9,12-13,18,21H,3-7,10-11,14-15,17H2,1-2H3,(H,28,30)(H,29,31)(H,33,34)/t18-,21+/m1/s1
PDB

Reactome pathway

UniProtKB/SwissProt

antibodypedia
antibodypedia
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a<50n/an/an/an/an/an/a



PLIANT THERAPEUTICS, INC.

US Patent


Assay Description
Microplates were coated with recombinant human integrin αVβ6 (2 μg/mL) in PBS (100 μL/well 25 C., overnight). The coating soluti...


US Patent US10793564 (2020)

More data for this
Ligand-Target Pair
Integrin alpha-V/alpha-5


(Homo sapiens (Human))
BDBM465288
PNG
(US10793564, Compound 77)
Show SMILES CO[C@H](C)CN(CCCCc1ccc2CCCNc2n1)CC[C@H](Nc1cc(ncn1)-n1cccn1)C(O)=O
Show InChI InChI=1S/C27H38N8O3/c1-20(38-2)18-34(14-4-3-8-22-10-9-21-7-5-12-28-26(21)32-22)16-11-23(27(36)37)33-24-17-25(30-19-29-24)35-15-6-13-31-35/h6,9-10,13,15,17,19-20,23H,3-5,7-8,11-12,14,16,18H2,1-2H3,(H,28,32)(H,36,37)(H,29,30,33)/t20-,23+/m1/s1
PDB

Reactome pathway

UniProtKB/SwissProt

antibodypedia
antibodypedia
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a<50n/an/an/an/an/an/a



PLIANT THERAPEUTICS, INC.

US Patent


Assay Description
Microplates were coated with recombinant human integrin αVβ6 (2 μg/mL) in PBS (100 μL/well 25 C., overnight). The coating soluti...


US Patent US10793564 (2020)

More data for this
Ligand-Target Pair
Integrin alpha-V/alpha-5


(Homo sapiens (Human))
BDBM465340
PNG
(US10793564, Compound 130)
Show SMILES OCC(CO)CN(CCCCc1ccc2CCCNc2n1)CC[C@H](Nc1ncnc2ccccc12)C(O)=O
Show InChI InChI=1S/C28H38N6O4/c35-17-20(18-36)16-34(14-4-3-7-22-11-10-21-6-5-13-29-26(21)32-22)15-12-25(28(37)38)33-27-23-8-1-2-9-24(23)30-19-31-27/h1-2,8-11,19-20,25,35-36H,3-7,12-18H2,(H,29,32)(H,37,38)(H,30,31,33)/t25-/m0/s1
PDB

Reactome pathway

UniProtKB/SwissProt

antibodypedia
antibodypedia
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a<50n/an/an/an/an/an/a



PLIANT THERAPEUTICS, INC.

US Patent


Assay Description
Microplates were coated with recombinant human integrin αVβ6 (2 μg/mL) in PBS (100 μL/well 25 C., overnight). The coating soluti...


US Patent US10793564 (2020)

More data for this
Ligand-Target Pair
Integrin alpha-V/alpha-5


(Homo sapiens (Human))
BDBM465348
PNG
(US10793564, Compound 138)
Show SMILES OC(=O)[C@H](CCN(CCCCc1ccc2CCCNc2n1)CCOc1ccc(F)cc1)Nc1ncc(cn1)C#N
Show InChI InChI=1S/C29H34FN7O3/c30-23-7-10-25(11-8-23)40-17-16-37(14-2-1-5-24-9-6-22-4-3-13-32-27(22)35-24)15-12-26(28(38)39)36-29-33-19-21(18-31)20-34-29/h6-11,19-20,26H,1-5,12-17H2,(H,32,35)(H,38,39)(H,33,34,36)/t26-/m0/s1
PDB

Reactome pathway

UniProtKB/SwissProt

antibodypedia
antibodypedia
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a<50n/an/an/an/an/an/a



PLIANT THERAPEUTICS, INC.

US Patent


Assay Description
Microplates were coated with recombinant human integrin αVβ6 (2 μg/mL) in PBS (100 μL/well 25 C., overnight). The coating soluti...


US Patent US10793564 (2020)

More data for this
Ligand-Target Pair
Integrin alpha-V/alpha-5


(Homo sapiens (Human))
BDBM465216
PNG
(US10793564, Compound 5 | US10793564, Compound 55)
Show SMILES COCCN(CCCCc1ccc2CCCNc2n1)CC[C@H](Nc1ncnc2ccccc12)C(O)=O
Show InChI InChI=1S/C27H36N6O3/c1-36-18-17-33(15-5-4-8-21-12-11-20-7-6-14-28-25(20)31-21)16-13-24(27(34)35)32-26-22-9-2-3-10-23(22)29-19-30-26/h2-3,9-12,19,24H,4-8,13-18H2,1H3,(H,28,31)(H,34,35)(H,29,30,32)/t24-/m0/s1
PDB

Reactome pathway

UniProtKB/SwissProt

antibodypedia
antibodypedia
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a<50n/an/an/an/an/an/a



PLIANT THERAPEUTICS, INC.

US Patent


Assay Description
Microplates were coated with recombinant human integrin αVβ6 (2 μg/mL) in PBS (100 μL/well 25 C., overnight). The coating soluti...


US Patent US10793564 (2020)

More data for this
Ligand-Target Pair
Integrin alpha-V/alpha-5


(Homo sapiens (Human))
BDBM465222
PNG
(US10793564, Compound 11)
Show SMILES COCCN(CCCCc1ccc2CCCNc2n1)CC[C@H](Nc1ncnc2ncccc12)C(O)=O
Show InChI InChI=1S/C26H35N7O3/c1-36-17-16-33(14-3-2-7-20-10-9-19-6-4-12-27-23(19)31-20)15-11-22(26(34)35)32-25-21-8-5-13-28-24(21)29-18-30-25/h5,8-10,13,18,22H,2-4,6-7,11-12,14-17H2,1H3,(H,27,31)(H,34,35)(H,28,29,30,32)/t22-/m0/s1
PDB

Reactome pathway

UniProtKB/SwissProt

antibodypedia
antibodypedia
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a<50n/an/an/an/an/an/a



PLIANT THERAPEUTICS, INC.

US Patent


Assay Description
Microplates were coated with recombinant human integrin αVβ6 (2 μg/mL) in PBS (100 μL/well 25 C., overnight). The coating soluti...


US Patent US10793564 (2020)

More data for this
Ligand-Target Pair
Integrin alpha-V/alpha-5


(Homo sapiens (Human))
BDBM465225
PNG
(US10793564, Compound 14)
Show SMILES COCCN(CCCCc1ccc2CCCNc2n1)CC[C@H](Nc1nc(nc2ccccc12)C(F)(F)F)C(O)=O
Show InChI InChI=1S/C28H35F3N6O3/c1-40-18-17-37(15-5-4-8-20-12-11-19-7-6-14-32-24(19)33-20)16-13-23(26(38)39)34-25-21-9-2-3-10-22(21)35-27(36-25)28(29,30)31/h2-3,9-12,23H,4-8,13-18H2,1H3,(H,32,33)(H,38,39)(H,34,35,36)/t23-/m0/s1
PDB

Reactome pathway

UniProtKB/SwissProt

antibodypedia
antibodypedia
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a<50n/an/an/an/an/an/a



PLIANT THERAPEUTICS, INC.

US Patent


Assay Description
Microplates were coated with recombinant human integrin αVβ6 (2 μg/mL) in PBS (100 μL/well 25 C., overnight). The coating soluti...


US Patent US10793564 (2020)

More data for this
Ligand-Target Pair
Integrin alpha-V/alpha-5


(Homo sapiens (Human))
BDBM465229
PNG
(US10793564, Compound 18)
Show SMILES COCCN(CCCCc1ccc2CCCNc2n1)CC[C@H](Nc1ncnc2cccc(F)c12)C(O)=O
Show InChI InChI=1S/C27H35FN6O3/c1-37-17-16-34(14-3-2-7-20-11-10-19-6-5-13-29-25(19)32-20)15-12-23(27(35)36)33-26-24-21(28)8-4-9-22(24)30-18-31-26/h4,8-11,18,23H,2-3,5-7,12-17H2,1H3,(H,29,32)(H,35,36)(H,30,31,33)/t23-/m0/s1
PDB

Reactome pathway

UniProtKB/SwissProt

antibodypedia
antibodypedia
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a<50n/an/an/an/an/an/a



PLIANT THERAPEUTICS, INC.

US Patent


Assay Description
Microplates were coated with recombinant human integrin αVβ6 (2 μg/mL) in PBS (100 μL/well 25 C., overnight). The coating soluti...


US Patent US10793564 (2020)

More data for this
Ligand-Target Pair
Integrin alpha-V/alpha-5


(Homo sapiens (Human))
BDBM465257
PNG
(US10793564, Compound 46)
Show SMILES COC[C@@H](F)CN(CCCCc1ccc2CCCNc2n1)CC[C@H](Nc1nc(C)nc2ccccc12)C(O)=O
Show InChI InChI=1S/C29H39FN6O3/c1-20-32-25-11-4-3-10-24(25)28(33-20)35-26(29(37)38)14-17-36(18-22(30)19-39-2)16-6-5-9-23-13-12-21-8-7-15-31-27(21)34-23/h3-4,10-13,22,26H,5-9,14-19H2,1-2H3,(H,31,34)(H,37,38)(H,32,33,35)/t22-,26-/m0/s1
PDB

Reactome pathway

UniProtKB/SwissProt

antibodypedia
antibodypedia
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a<50n/an/an/an/an/an/a



PLIANT THERAPEUTICS, INC.

US Patent


Assay Description
Microplates were coated with recombinant human integrin αVβ6 (2 μg/mL) in PBS (100 μL/well 25 C., overnight). The coating soluti...


US Patent US10793564 (2020)

More data for this
Ligand-Target Pair
Integrin alpha-V/alpha-5


(Homo sapiens (Human))
BDBM465258
PNG
(US10793564, Compound 47)
Show SMILES OC(=O)[C@H](CCN(CCCCc1ccc2CCCNc2n1)CCOc1cc(F)cc(F)c1)Nc1ncnc2ccccc12
Show InChI InChI=1S/C32H36F2N6O3/c33-23-18-24(34)20-26(19-23)43-17-16-40(14-4-3-7-25-11-10-22-6-5-13-35-30(22)38-25)15-12-29(32(41)42)39-31-27-8-1-2-9-28(27)36-21-37-31/h1-2,8-11,18-21,29H,3-7,12-17H2,(H,35,38)(H,41,42)(H,36,37,39)/t29-/m0/s1
PDB

Reactome pathway

UniProtKB/SwissProt

antibodypedia
antibodypedia
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a<50n/an/an/an/an/an/a



PLIANT THERAPEUTICS, INC.

US Patent


Assay Description
Microplates were coated with recombinant human integrin αVβ6 (2 μg/mL) in PBS (100 μL/well 25 C., overnight). The coating soluti...


US Patent US10793564 (2020)

More data for this
Ligand-Target Pair
Integrin alpha-V/alpha-5


(Homo sapiens (Human))
BDBM465265
PNG
(US10793564, Compound 54)
Show SMILES Cc1ncccc1OCCN(CCCCc1ccc2CCCNc2n1)CC[C@H](Nc1ncnc2cccnc12)C(O)=O
Show InChI InChI=1S/C31H38N8O3/c1-22-27(10-6-14-32-22)42-20-19-39(17-3-2-8-24-12-11-23-7-4-16-34-29(23)37-24)18-13-26(31(40)41)38-30-28-25(35-21-36-30)9-5-15-33-28/h5-6,9-12,14-15,21,26H,2-4,7-8,13,16-20H2,1H3,(H,34,37)(H,40,41)(H,35,36,38)/t26-/m0/s1
PDB

Reactome pathway

UniProtKB/SwissProt

antibodypedia
antibodypedia
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a<50n/an/an/an/an/an/a



PLIANT THERAPEUTICS, INC.

US Patent


Assay Description
Microplates were coated with recombinant human integrin αVβ6 (2 μg/mL) in PBS (100 μL/well 25 C., overnight). The coating soluti...


US Patent US10793564 (2020)

More data for this
Ligand-Target Pair
Integrin alpha-V/alpha-5


(Homo sapiens (Human))
BDBM465305
PNG
(US10793564, Compound 94)
Show SMILES OC(=O)[C@H](CCN(CCCCc1ccc2CCCNc2n1)CCOc1ccccc1)Nc1nc(nc2ccccc12)-c1cccnc1
Show InChI InChI=1S/C37H41N7O3/c45-37(46)33(42-36-31-15-4-5-16-32(31)41-35(43-36)28-11-8-20-38-26-28)19-23-44(24-25-47-30-13-2-1-3-14-30)22-7-6-12-29-18-17-27-10-9-21-39-34(27)40-29/h1-5,8,11,13-18,20,26,33H,6-7,9-10,12,19,21-25H2,(H,39,40)(H,45,46)(H,41,42,43)/t33-/m0/s1
PDB

Reactome pathway

UniProtKB/SwissProt

antibodypedia
antibodypedia
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a<50n/an/an/an/an/an/a



PLIANT THERAPEUTICS, INC.

US Patent


Assay Description
Microplates were coated with recombinant human integrin αVβ6 (2 μg/mL) in PBS (100 μL/well 25 C., overnight). The coating soluti...


US Patent US10793564 (2020)

More data for this
Ligand-Target Pair
Integrin alpha-V/alpha-5


(Homo sapiens (Human))
BDBM465321
PNG
(US10793564, Compound 110)
Show SMILES COC[C@@H](F)CN(CCCCc1ccc2CCCNc2n1)CC[C@H](Nc1ncncc1-c1ccccc1)C(O)=O
Show InChI InChI=1S/C30H39FN6O3/c1-40-20-24(31)19-37(16-6-5-11-25-13-12-23-10-7-15-33-28(23)35-25)17-14-27(30(38)39)36-29-26(18-32-21-34-29)22-8-3-2-4-9-22/h2-4,8-9,12-13,18,21,24,27H,5-7,10-11,14-17,19-20H2,1H3,(H,33,35)(H,38,39)(H,32,34,36)/t24-,27-/m0/s1
PDB

Reactome pathway

UniProtKB/SwissProt

antibodypedia
antibodypedia
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a<50n/an/an/an/an/an/a



PLIANT THERAPEUTICS, INC.

US Patent


Assay Description
Microplates were coated with recombinant human integrin αVβ6 (2 μg/mL) in PBS (100 μL/well 25 C., overnight). The coating soluti...


US Patent US10793564 (2020)

More data for this
Ligand-Target Pair
Integrin alpha-V/alpha-5


(Homo sapiens (Human))
BDBM465339
PNG
(US10793564, Compound 129)
Show SMILES OC(=O)[C@H](CCN(CCCCc1ccc2CCCNc2n1)CC1CCO1)Nc1ncnc2ccccc12
Show InChI InChI=1S/C28H36N6O3/c35-28(36)25(33-27-23-8-1-2-9-24(23)30-19-31-27)12-16-34(18-22-13-17-37-22)15-4-3-7-21-11-10-20-6-5-14-29-26(20)32-21/h1-2,8-11,19,22,25H,3-7,12-18H2,(H,29,32)(H,35,36)(H,30,31,33)/t22?,25-/m0/s1
PDB

Reactome pathway

UniProtKB/SwissProt

antibodypedia
antibodypedia
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a<50n/an/an/an/an/an/a



PLIANT THERAPEUTICS, INC.

US Patent


Assay Description
Microplates were coated with recombinant human integrin αVβ6 (2 μg/mL) in PBS (100 μL/well 25 C., overnight). The coating soluti...


US Patent US10793564 (2020)

More data for this
Ligand-Target Pair
Integrin alpha-V/alpha-5


(Homo sapiens (Human))
BDBM465221
PNG
(US10793564, Compound 10)
Show SMILES COCCN(CCCCc1ccc2CCCNc2n1)CC[C@H](Nc1nc(C)nc2ccccc12)C(O)=O
Show InChI InChI=1S/C28H38N6O3/c1-20-30-24-11-4-3-10-23(24)27(31-20)33-25(28(35)36)14-17-34(18-19-37-2)16-6-5-9-22-13-12-21-8-7-15-29-26(21)32-22/h3-4,10-13,25H,5-9,14-19H2,1-2H3,(H,29,32)(H,35,36)(H,30,31,33)/t25-/m0/s1
PDB

Reactome pathway

UniProtKB/SwissProt

antibodypedia
antibodypedia
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a<50n/an/an/an/an/an/a



PLIANT THERAPEUTICS, INC.

US Patent


Assay Description
Microplates were coated with recombinant human integrin αVβ6 (2 μg/mL) in PBS (100 μL/well 25 C., overnight). The coating soluti...


US Patent US10793564 (2020)

More data for this
Ligand-Target Pair
Integrin alpha-V/alpha-5


(Homo sapiens (Human))
BDBM465233
PNG
(US10793564, Compound 22)
Show SMILES COCCN(CCCCc1ccc2CCCNc2n1)CC[C@H](Nc1cc(nc(C)n1)C(F)(F)F)C(O)=O
Show InChI InChI=1S/C25H35F3N6O3/c1-17-30-21(25(26,27)28)16-22(31-17)33-20(24(35)36)10-13-34(14-15-37-2)12-4-3-7-19-9-8-18-6-5-11-29-23(18)32-19/h8-9,16,20H,3-7,10-15H2,1-2H3,(H,29,32)(H,35,36)(H,30,31,33)/t20-/m0/s1
PDB

Reactome pathway

UniProtKB/SwissProt

antibodypedia
antibodypedia
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a<50n/an/an/an/an/an/a



PLIANT THERAPEUTICS, INC.

US Patent


Assay Description
Microplates were coated with recombinant human integrin αVβ6 (2 μg/mL) in PBS (100 μL/well 25 C., overnight). The coating soluti...


US Patent US10793564 (2020)

More data for this
Ligand-Target Pair
Integrin alpha-V/alpha-5


(Homo sapiens (Human))
BDBM465236
PNG
(US10793564, Compound 25)
Show SMILES CO[C@@H](C)CN(CCCCc1ccc2CCCNc2n1)CC[C@H](Nc1ncnc2ccccc12)C(O)=O
Show InChI InChI=1S/C28H38N6O3/c1-20(37-2)18-34(16-6-5-9-22-13-12-21-8-7-15-29-26(21)32-22)17-14-25(28(35)36)33-27-23-10-3-4-11-24(23)30-19-31-27/h3-4,10-13,19-20,25H,5-9,14-18H2,1-2H3,(H,29,32)(H,35,36)(H,30,31,33)/t20-,25-/m0/s1
PDB

Reactome pathway

UniProtKB/SwissProt

antibodypedia
antibodypedia
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a<50n/an/an/an/an/an/a



PLIANT THERAPEUTICS, INC.

US Patent


Assay Description
Microplates were coated with recombinant human integrin αVβ6 (2 μg/mL) in PBS (100 μL/well 25 C., overnight). The coating soluti...


US Patent US10793564 (2020)

More data for this
Ligand-Target Pair
Integrin alpha-V/alpha-5


(Homo sapiens (Human))
BDBM465238
PNG
(US10793564, Compound 27)
Show SMILES CS(=O)(=O)CCN(CCCCc1ccc2CCCNc2n1)CC[C@H](Nc1ncnc2ccccc12)C(O)=O
Show InChI InChI=1S/C27H36N6O4S/c1-38(36,37)18-17-33(15-5-4-8-21-12-11-20-7-6-14-28-25(20)31-21)16-13-24(27(34)35)32-26-22-9-2-3-10-23(22)29-19-30-26/h2-3,9-12,19,24H,4-8,13-18H2,1H3,(H,28,31)(H,34,35)(H,29,30,32)/t24-/m0/s1
PDB

Reactome pathway

UniProtKB/SwissProt

antibodypedia
antibodypedia
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a<50n/an/an/an/an/an/a



PLIANT THERAPEUTICS, INC.

US Patent


Assay Description
Microplates were coated with recombinant human integrin αVβ6 (2 μg/mL) in PBS (100 μL/well 25 C., overnight). The coating soluti...


US Patent US10793564 (2020)

More data for this
Ligand-Target Pair
Integrin alpha-V/alpha-5


(Homo sapiens (Human))
BDBM465244
PNG
(US10793564, Compound 33)
Show SMILES Cc1nc(N[C@@H](CCN(CCCCc2ccc3CCCNc3n2)CC2CC(F)(F)C2)C(O)=O)c2ccc(F)cc2n1
Show InChI InChI=1S/C30H37F3N6O2/c1-19-35-26-15-22(31)8-10-24(26)28(36-19)38-25(29(40)41)11-14-39(18-20-16-30(32,33)17-20)13-3-2-6-23-9-7-21-5-4-12-34-27(21)37-23/h7-10,15,20,25H,2-6,11-14,16-18H2,1H3,(H,34,37)(H,40,41)(H,35,36,38)/t25-/m0/s1
PDB

Reactome pathway

UniProtKB/SwissProt

antibodypedia
antibodypedia
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a<50n/an/an/an/an/an/a



PLIANT THERAPEUTICS, INC.

US Patent


Assay Description
Microplates were coated with recombinant human integrin αVβ6 (2 μg/mL) in PBS (100 μL/well 25 C., overnight). The coating soluti...


US Patent US10793564 (2020)

More data for this
Ligand-Target Pair
Integrin alpha-V/alpha-5


(Homo sapiens (Human))
BDBM465249
PNG
(US10793564, Compound 38)
Show SMILES COCCN(CCCCc1ccc2CCCNc2n1)CC[C@H](Nc1ncnc2c(Cl)cccc12)C(O)=O
Show InChI InChI=1S/C27H35ClN6O3/c1-37-17-16-34(14-3-2-7-20-11-10-19-6-5-13-29-25(19)32-20)15-12-23(27(35)36)33-26-21-8-4-9-22(28)24(21)30-18-31-26/h4,8-11,18,23H,2-3,5-7,12-17H2,1H3,(H,29,32)(H,35,36)(H,30,31,33)/t23-/m0/s1
PDB

Reactome pathway

UniProtKB/SwissProt

antibodypedia
antibodypedia
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a<50n/an/an/an/an/an/a



PLIANT THERAPEUTICS, INC.

US Patent


Assay Description
Microplates were coated with recombinant human integrin αVβ6 (2 μg/mL) in PBS (100 μL/well 25 C., overnight). The coating soluti...


US Patent US10793564 (2020)

More data for this
Ligand-Target Pair
Integrin alpha-V/alpha-5


(Homo sapiens (Human))
BDBM465251
PNG
(US10793564, Compound 40)
Show SMILES Cc1nc(N[C@@H](CCN(CCCCc2ccc3CCCNc3n2)CCOc2ccc(F)cc2)C(O)=O)c2ccc(F)cc2n1
Show InChI InChI=1S/C33H38F2N6O3/c1-22-37-30-21-25(35)10-14-28(30)32(38-22)40-29(33(42)43)15-18-41(19-20-44-27-12-8-24(34)9-13-27)17-3-2-6-26-11-7-23-5-4-16-36-31(23)39-26/h7-14,21,29H,2-6,15-20H2,1H3,(H,36,39)(H,42,43)(H,37,38,40)/t29-/m0/s1
PDB

Reactome pathway

UniProtKB/SwissProt

antibodypedia
antibodypedia
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a<50n/an/an/an/an/an/a



PLIANT THERAPEUTICS, INC.

US Patent


Assay Description
Microplates were coated with recombinant human integrin αVβ6 (2 μg/mL) in PBS (100 μL/well 25 C., overnight). The coating soluti...


US Patent US10793564 (2020)

More data for this
Ligand-Target Pair
Integrin alpha-V/alpha-5


(Homo sapiens (Human))
BDBM465267
PNG
(US10793564, Compound 56)
Show SMILES Cc1ccc(OCCN(CCCCc2ccc3CCCNc3n2)CC[C@H](Nc2nc(C)nc3cc(F)ccc23)C(O)=O)cn1
Show InChI InChI=1S/C33H40FN7O3/c1-22-8-12-27(21-36-22)44-19-18-41(16-4-3-7-26-11-9-24-6-5-15-35-31(24)39-26)17-14-29(33(42)43)40-32-28-13-10-25(34)20-30(28)37-23(2)38-32/h8-13,20-21,29H,3-7,14-19H2,1-2H3,(H,35,39)(H,42,43)(H,37,38,40)/t29-/m0/s1
PDB

Reactome pathway

UniProtKB/SwissProt

antibodypedia
antibodypedia
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a<50n/an/an/an/an/an/a



PLIANT THERAPEUTICS, INC.

US Patent


Assay Description
Microplates were coated with recombinant human integrin αVβ6 (2 μg/mL) in PBS (100 μL/well 25 C., overnight). The coating soluti...


US Patent US10793564 (2020)

More data for this
Ligand-Target Pair
Integrin alpha-V/alpha-5


(Homo sapiens (Human))
BDBM465277
PNG
(US10793564, Compound 66)
Show SMILES CO[C@H](C)CN(CCCCc1ccc2CCCNc2n1)CC[C@H](Nc1nc(C)nc2ccccc12)C(O)=O
Show InChI InChI=1S/C29H40N6O3/c1-20(38-3)19-35(17-7-6-10-23-14-13-22-9-8-16-30-27(22)33-23)18-15-26(29(36)37)34-28-24-11-4-5-12-25(24)31-21(2)32-28/h4-5,11-14,20,26H,6-10,15-19H2,1-3H3,(H,30,33)(H,36,37)(H,31,32,34)/t20-,26+/m1/s1
PDB

Reactome pathway

UniProtKB/SwissProt

antibodypedia
antibodypedia
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a<50n/an/an/an/an/an/a



PLIANT THERAPEUTICS, INC.

US Patent


Assay Description
Microplates were coated with recombinant human integrin αVβ6 (2 μg/mL) in PBS (100 μL/well 25 C., overnight). The coating soluti...


US Patent US10793564 (2020)

More data for this
Ligand-Target Pair
Integrin alpha-V/alpha-5


(Homo sapiens (Human))
BDBM465278
PNG
(US10793564, Compound 67)
Show SMILES COCCN(CCCCc1ccc2CCCNc2n1)CC[C@H](Nc1nccnc1C#N)C(O)=O
Show InChI InChI=1S/C24H33N7O3/c1-34-16-15-31(13-3-2-6-19-8-7-18-5-4-10-27-22(18)29-19)14-9-20(24(32)33)30-23-21(17-25)26-11-12-28-23/h7-8,11-12,20H,2-6,9-10,13-16H2,1H3,(H,27,29)(H,28,30)(H,32,33)/t20-/m0/s1
PDB

Reactome pathway

UniProtKB/SwissProt

antibodypedia
antibodypedia
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a<50n/an/an/an/an/an/a



PLIANT THERAPEUTICS, INC.

US Patent


Assay Description
Microplates were coated with recombinant human integrin αVβ6 (2 μg/mL) in PBS (100 μL/well 25 C., overnight). The coating soluti...


US Patent US10793564 (2020)

More data for this
Ligand-Target Pair
Integrin alpha-V/alpha-5


(Homo sapiens (Human))
BDBM465280
PNG
(US10793564, Compound 69)
Show SMILES CO[C@H](C)CN(CCCCc1ccc2CCCNc2n1)CC[C@H](Nc1ncc(cn1)C(F)(F)F)C(O)=O
Show InChI InChI=1S/C25H35F3N6O3/c1-17(37-2)16-34(12-4-3-7-20-9-8-18-6-5-11-29-22(18)32-20)13-10-21(23(35)36)33-24-30-14-19(15-31-24)25(26,27)28/h8-9,14-15,17,21H,3-7,10-13,16H2,1-2H3,(H,29,32)(H,35,36)(H,30,31,33)/t17-,21+/m1/s1
PDB

Reactome pathway

UniProtKB/SwissProt

antibodypedia
antibodypedia
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a<50n/an/an/an/an/an/a



PLIANT THERAPEUTICS, INC.

US Patent


Assay Description
Microplates were coated with recombinant human integrin αVβ6 (2 μg/mL) in PBS (100 μL/well 25 C., overnight). The coating soluti...


US Patent US10793564 (2020)

More data for this
Ligand-Target Pair
Integrin alpha-V/alpha-5


(Homo sapiens (Human))
BDBM465294
PNG
(US10793564, Compound 83)
Show SMILES OC(=O)[C@H](CCN(CCCCc1ccc2CCCNc2n1)CCOc1ccccc1)Nc1ncc(Br)cn1
Show InChI InChI=1S/C28H35BrN6O3/c29-22-19-31-28(32-20-22)34-25(27(36)37)13-16-35(17-18-38-24-9-2-1-3-10-24)15-5-4-8-23-12-11-21-7-6-14-30-26(21)33-23/h1-3,9-12,19-20,25H,4-8,13-18H2,(H,30,33)(H,36,37)(H,31,32,34)/t25-/m0/s1
PDB

Reactome pathway

UniProtKB/SwissProt

antibodypedia
antibodypedia
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a<50n/an/an/an/an/an/a



PLIANT THERAPEUTICS, INC.

US Patent


Assay Description
Microplates were coated with recombinant human integrin αVβ6 (2 μg/mL) in PBS (100 μL/well 25 C., overnight). The coating soluti...


US Patent US10793564 (2020)

More data for this
Ligand-Target Pair
Integrin alpha-V/alpha-5


(Homo sapiens (Human))
BDBM465304
PNG
(US10793564, Compound 93)
Show SMILES OC(=O)[C@H](CCN(CCCCc1ccc2CCCNc2n1)CCOc1ccccc1)Nc1cc(ncn1)-c1ccccc1
Show InChI InChI=1S/C34H40N6O3/c41-34(42)30(39-32-24-31(36-25-37-32)26-10-3-1-4-11-26)18-21-40(22-23-43-29-14-5-2-6-15-29)20-8-7-13-28-17-16-27-12-9-19-35-33(27)38-28/h1-6,10-11,14-17,24-25,30H,7-9,12-13,18-23H2,(H,35,38)(H,41,42)(H,36,37,39)/t30-/m0/s1
PDB

Reactome pathway

UniProtKB/SwissProt

antibodypedia
antibodypedia
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a<50n/an/an/an/an/an/a



PLIANT THERAPEUTICS, INC.

US Patent


Assay Description
Microplates were coated with recombinant human integrin αVβ6 (2 μg/mL) in PBS (100 μL/well 25 C., overnight). The coating soluti...


US Patent US10793564 (2020)

More data for this
Ligand-Target Pair
Integrin alpha-V/alpha-5


(Homo sapiens (Human))
BDBM465311
PNG
(US10793564, Compound 100)
Show SMILES CO[C@H](C)CN(CCCCc1ccc2CCCNc2n1)CC[C@H](Nc1nc(nc2ccccc12)-c1cccnc1)C(O)=O
Show InChI InChI=1S/C33H41N7O3/c1-23(43-2)22-40(19-6-5-11-26-15-14-24-9-8-18-35-30(24)36-26)20-16-29(33(41)42)38-32-27-12-3-4-13-28(27)37-31(39-32)25-10-7-17-34-21-25/h3-4,7,10,12-15,17,21,23,29H,5-6,8-9,11,16,18-20,22H2,1-2H3,(H,35,36)(H,41,42)(H,37,38,39)/t23-,29+/m1/s1
PDB

Reactome pathway

UniProtKB/SwissProt

antibodypedia
antibodypedia
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a<50n/an/an/an/an/an/a



PLIANT THERAPEUTICS, INC.

US Patent


Assay Description
Microplates were coated with recombinant human integrin αVβ6 (2 μg/mL) in PBS (100 μL/well 25 C., overnight). The coating soluti...


US Patent US10793564 (2020)

More data for this
Ligand-Target Pair
Integrin alpha-V/alpha-5


(Homo sapiens (Human))
BDBM465317
PNG
(US10793564, Compound 106)
Show SMILES CO[C@H](C)CN(CCCCc1ccc2CCCNc2n1)CC[C@H](Nc1ccncn1)C(O)=O
Show InChI InChI=1S/C24H36N6O3/c1-18(33-2)16-30(15-11-21(24(31)32)29-22-10-13-25-17-27-22)14-4-3-7-20-9-8-19-6-5-12-26-23(19)28-20/h8-10,13,17-18,21H,3-7,11-12,14-16H2,1-2H3,(H,26,28)(H,31,32)(H,25,27,29)/t18-,21+/m1/s1
PDB

Reactome pathway

UniProtKB/SwissProt

antibodypedia
antibodypedia
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a<50n/an/an/an/an/an/a



PLIANT THERAPEUTICS, INC.

US Patent


Assay Description
Microplates were coated with recombinant human integrin αVβ6 (2 μg/mL) in PBS (100 μL/well 25 C., overnight). The coating soluti...


US Patent US10793564 (2020)

More data for this
Ligand-Target Pair
Integrin alpha-V/alpha-5


(Homo sapiens (Human))
BDBM465230
PNG
(US10793564, Compound 19)
Show SMILES COCCN(CCCCc1ccc2CCCNc2n1)CC[C@H](Nc1ncnc2ccc(F)cc12)C(O)=O
Show InChI InChI=1S/C27H35FN6O3/c1-37-16-15-34(13-3-2-6-21-9-7-19-5-4-12-29-25(19)32-21)14-11-24(27(35)36)33-26-22-17-20(28)8-10-23(22)30-18-31-26/h7-10,17-18,24H,2-6,11-16H2,1H3,(H,29,32)(H,35,36)(H,30,31,33)/t24-/m0/s1
PDB

Reactome pathway

UniProtKB/SwissProt

antibodypedia
antibodypedia
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a<50n/an/an/an/an/an/a



PLIANT THERAPEUTICS, INC.

US Patent


Assay Description
Microplates were coated with recombinant human integrin αVβ6 (2 μg/mL) in PBS (100 μL/well 25 C., overnight). The coating soluti...


US Patent US10793564 (2020)

More data for this
Ligand-Target Pair
Integrin alpha-V/alpha-5


(Homo sapiens (Human))
BDBM465239
PNG
(US10793564, Compound 28)
Show SMILES OC(=O)[C@H](CCN(CCCCc1ccc2CCCNc2n1)CCOc1ccccc1)Nc1ncnc2ccccc12
Show InChI InChI=1S/C32H38N6O3/c39-32(40)29(37-31-27-13-4-5-14-28(27)34-23-35-31)17-20-38(21-22-41-26-11-2-1-3-12-26)19-7-6-10-25-16-15-24-9-8-18-33-30(24)36-25/h1-5,11-16,23,29H,6-10,17-22H2,(H,33,36)(H,39,40)(H,34,35,37)/t29-/m0/s1
PDB

Reactome pathway

UniProtKB/SwissProt

antibodypedia
antibodypedia
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a<50n/an/an/an/an/an/a



PLIANT THERAPEUTICS, INC.

US Patent


Assay Description
Microplates were coated with recombinant human integrin αVβ6 (2 μg/mL) in PBS (100 μL/well 25 C., overnight). The coating soluti...


US Patent US10793564 (2020)

More data for this
Ligand-Target Pair
Integrin alpha-V/alpha-5


(Homo sapiens (Human))
BDBM465243
PNG
(US10793564, Compound 32)
Show SMILES COC[C@@H](F)CN(CCCCc1ccc2CCCNc2n1)CC[C@H](Nc1nc(C)nc2cc(F)ccc12)C(O)=O
Show InChI InChI=1S/C29H38F2N6O3/c1-19-33-26-16-21(30)9-11-24(26)28(34-19)36-25(29(38)39)12-15-37(17-22(31)18-40-2)14-4-3-7-23-10-8-20-6-5-13-32-27(20)35-23/h8-11,16,22,25H,3-7,12-15,17-18H2,1-2H3,(H,32,35)(H,38,39)(H,33,34,36)/t22-,25-/m0/s1
PDB

Reactome pathway

UniProtKB/SwissProt

antibodypedia
antibodypedia
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a<50n/an/an/an/an/an/a



PLIANT THERAPEUTICS, INC.

US Patent


Assay Description
Microplates were coated with recombinant human integrin αVβ6 (2 μg/mL) in PBS (100 μL/well 25 C., overnight). The coating soluti...


US Patent US10793564 (2020)

More data for this
Ligand-Target Pair
Integrin alpha-V/alpha-5


(Homo sapiens (Human))
BDBM465260
PNG
(US10793564, Compound 49)
Show SMILES OC(=O)[C@H](CCN(CCCCc1ccc2CCCNc2n1)CCOc1ccccn1)Nc1ncnc2ccccc12
Show InChI InChI=1S/C31H37N7O3/c39-31(40)27(37-30-25-10-1-2-11-26(25)34-22-35-30)15-19-38(20-21-41-28-12-3-5-16-32-28)18-6-4-9-24-14-13-23-8-7-17-33-29(23)36-24/h1-3,5,10-14,16,22,27H,4,6-9,15,17-21H2,(H,33,36)(H,39,40)(H,34,35,37)/t27-/m0/s1
PDB

Reactome pathway

UniProtKB/SwissProt

antibodypedia
antibodypedia
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a<50n/an/an/an/an/an/a



PLIANT THERAPEUTICS, INC.

US Patent


Assay Description
Microplates were coated with recombinant human integrin αVβ6 (2 μg/mL) in PBS (100 μL/well 25 C., overnight). The coating soluti...


US Patent US10793564 (2020)

More data for this
Ligand-Target Pair
Integrin alpha-V/alpha-5


(Homo sapiens (Human))
BDBM465290
PNG
(US10793564, Compound 79)
Show SMILES CO[C@H](C)CN(CCCCc1ccc2CCCNc2n1)CC[C@H](Nc1ncnc2cn[nH]c12)C(O)=O
Show InChI InChI=1S/C25H36N8O3/c1-17(36-2)15-33(12-4-3-7-19-9-8-18-6-5-11-26-23(18)30-19)13-10-20(25(34)35)31-24-22-21(14-29-32-22)27-16-28-24/h8-9,14,16-17,20H,3-7,10-13,15H2,1-2H3,(H,26,30)(H,29,32)(H,34,35)(H,27,28,31)/t17-,20+/m1/s1
PDB

Reactome pathway

UniProtKB/SwissProt

antibodypedia
antibodypedia
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a<50n/an/an/an/an/an/a



PLIANT THERAPEUTICS, INC.

US Patent


Assay Description
Microplates were coated with recombinant human integrin αVβ6 (2 μg/mL) in PBS (100 μL/well 25 C., overnight). The coating soluti...


US Patent US10793564 (2020)

More data for this
Ligand-Target Pair
Integrin alpha-V/alpha-5


(Homo sapiens (Human))
BDBM465300
PNG
(US10793564, Compound 89)
Show SMILES OC(=O)[C@H](CCN(CCCCc1ccc2CCCNc2n1)CCOc1ccccc1)Nc1ncc(cn1)C(F)(F)F
Show InChI InChI=1S/C29H35F3N6O3/c30-29(31,32)22-19-34-28(35-20-22)37-25(27(39)40)13-16-38(17-18-41-24-9-2-1-3-10-24)15-5-4-8-23-12-11-21-7-6-14-33-26(21)36-23/h1-3,9-12,19-20,25H,4-8,13-18H2,(H,33,36)(H,39,40)(H,34,35,37)/t25-/m0/s1
PDB

Reactome pathway

UniProtKB/SwissProt

antibodypedia
antibodypedia
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a<50n/an/an/an/an/an/a



PLIANT THERAPEUTICS, INC.

US Patent


Assay Description
Microplates were coated with recombinant human integrin αVβ6 (2 μg/mL) in PBS (100 μL/well 25 C., overnight). The coating soluti...


US Patent US10793564 (2020)

More data for this
Ligand-Target Pair
Integrin alpha-V/alpha-5


(Homo sapiens (Human))
BDBM465301
PNG
(US10793564, Compound 90)
Show SMILES OC(=O)[C@H](CCN(CCCCc1ccc2CCCNc2n1)CCOc1ccccc1)Nc1ncnc2[nH]ncc12
Show InChI InChI=1S/C29H36N8O3/c38-29(39)25(35-27-24-19-33-36-28(24)32-20-31-27)13-16-37(17-18-40-23-9-2-1-3-10-23)15-5-4-8-22-12-11-21-7-6-14-30-26(21)34-22/h1-3,9-12,19-20,25H,4-8,13-18H2,(H,30,34)(H,38,39)(H2,31,32,33,35,36)/t25-/m0/s1
PDB

Reactome pathway

UniProtKB/SwissProt

antibodypedia
antibodypedia
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a<50n/an/an/an/an/an/a



PLIANT THERAPEUTICS, INC.

US Patent


Assay Description
Microplates were coated with recombinant human integrin αVβ6 (2 μg/mL) in PBS (100 μL/well 25 C., overnight). The coating soluti...


US Patent US10793564 (2020)

More data for this
Ligand-Target Pair
Integrin alpha-V/alpha-5


(Homo sapiens (Human))
BDBM465303
PNG
(US10793564, Compound 92)
Show SMILES OC(=O)[C@H](CCN(CCCCc1ccc2CCCNc2n1)CCOc1ccccc1)Nc1ccnc(n1)C(F)(F)F
Show InChI InChI=1S/C29H35F3N6O3/c30-29(31,32)28-34-16-13-25(37-28)36-24(27(39)40)14-18-38(19-20-41-23-9-2-1-3-10-23)17-5-4-8-22-12-11-21-7-6-15-33-26(21)35-22/h1-3,9-13,16,24H,4-8,14-15,17-20H2,(H,33,35)(H,39,40)(H,34,36,37)/t24-/m0/s1
PDB

Reactome pathway

UniProtKB/SwissProt

antibodypedia
antibodypedia
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a<50n/an/an/an/an/an/a



PLIANT THERAPEUTICS, INC.

US Patent


Assay Description
Microplates were coated with recombinant human integrin αVβ6 (2 μg/mL) in PBS (100 μL/well 25 C., overnight). The coating soluti...


US Patent US10793564 (2020)

More data for this
Ligand-Target Pair
Integrin alpha-V/alpha-5


(Homo sapiens (Human))
BDBM465320
PNG
(US10793564, Compound 109)
Show SMILES COC[C@@H](F)CN(CCCCc1ccc2CCCNc2n1)CC[C@H](Nc1nc(nc2ccccc12)-c1cccnc1)C(O)=O
Show InChI InChI=1S/C33H40FN7O3/c1-44-22-25(34)21-41(18-5-4-10-26-14-13-23-8-7-17-36-30(23)37-26)19-15-29(33(42)43)39-32-27-11-2-3-12-28(27)38-31(40-32)24-9-6-16-35-20-24/h2-3,6,9,11-14,16,20,25,29H,4-5,7-8,10,15,17-19,21-22H2,1H3,(H,36,37)(H,42,43)(H,38,39,40)/t25-,29-/m0/s1
PDB

Reactome pathway

UniProtKB/SwissProt

antibodypedia
antibodypedia
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a<50n/an/an/an/an/an/a



PLIANT THERAPEUTICS, INC.

US Patent


Assay Description
Microplates were coated with recombinant human integrin αVβ6 (2 μg/mL) in PBS (100 μL/well 25 C., overnight). The coating soluti...


US Patent US10793564 (2020)

More data for this
Ligand-Target Pair
Integrin alpha-V/alpha-5


(Homo sapiens (Human))
BDBM465322
PNG
(US10793564, Compound 111)
Show SMILES OC(=O)[C@H](CCN(CCCCc1ccc2CCCNc2n1)CCOc1ccccc1)Nc1ncc(cn1)C#N
Show InChI InChI=1S/C29H35N7O3/c30-19-22-20-32-29(33-21-22)35-26(28(37)38)13-16-36(17-18-39-25-9-2-1-3-10-25)15-5-4-8-24-12-11-23-7-6-14-31-27(23)34-24/h1-3,9-12,20-21,26H,4-8,13-18H2,(H,31,34)(H,37,38)(H,32,33,35)/t26-/m0/s1
PDB

Reactome pathway

UniProtKB/SwissProt

antibodypedia
antibodypedia
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a<50n/an/an/an/an/an/a



PLIANT THERAPEUTICS, INC.

US Patent


Assay Description
Microplates were coated with recombinant human integrin αVβ6 (2 μg/mL) in PBS (100 μL/well 25 C., overnight). The coating soluti...


US Patent US10793564 (2020)

More data for this
Ligand-Target Pair
Integrin alpha-V/alpha-5


(Homo sapiens (Human))
BDBM465349
PNG
(US10793564, Compound 139)
Show SMILES OC(=O)[C@H](CCN(CCCCc1ccc2CCCNc2n1)CCOc1ccc(F)cc1)Nc1ncc(cn1)C(F)(F)F
Show InChI InChI=1S/C29H34F4N6O3/c30-22-7-10-24(11-8-22)42-17-16-39(14-2-1-5-23-9-6-20-4-3-13-34-26(20)37-23)15-12-25(27(40)41)38-28-35-18-21(19-36-28)29(31,32)33/h6-11,18-19,25H,1-5,12-17H2,(H,34,37)(H,40,41)(H,35,36,38)/t25-/m0/s1
PDB

Reactome pathway

UniProtKB/SwissProt

antibodypedia
antibodypedia
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a<50n/an/an/an/an/an/a



PLIANT THERAPEUTICS, INC.

US Patent


Assay Description
Microplates were coated with recombinant human integrin αVβ6 (2 μg/mL) in PBS (100 μL/well 25 C., overnight). The coating soluti...


US Patent US10793564 (2020)

More data for this
Ligand-Target Pair
Integrin alpha-V/alpha-5


(Homo sapiens (Human))
BDBM465350
PNG
(US10793564, Compound 140)
Show SMILES CN(C)C(=O)CN(CCCCc1ccc2CCCNc2n1)CC[C@H](Nc1ncnc2n(C)ncc12)C(O)=O
Show InChI InChI=1S/C26H37N9O3/c1-33(2)22(36)16-35(13-5-4-8-19-10-9-18-7-6-12-27-23(18)31-19)14-11-21(26(37)38)32-24-20-15-30-34(3)25(20)29-17-28-24/h9-10,15,17,21H,4-8,11-14,16H2,1-3H3,(H,27,31)(H,37,38)(H,28,29,32)/t21-/m0/s1
PDB

Reactome pathway

UniProtKB/SwissProt

antibodypedia
antibodypedia
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a<50n/an/an/an/an/an/a



PLIANT THERAPEUTICS, INC.

US Patent


Assay Description
Microplates were coated with recombinant human integrin αVβ6 (2 μg/mL) in PBS (100 μL/well 25 C., overnight). The coating soluti...


US Patent US10793564 (2020)

More data for this
Ligand-Target Pair
Integrin alpha-V/alpha-5


(Homo sapiens (Human))
BDBM465223
PNG
(US10793564, Compound 12)
Show SMILES COCCN(CCCCc1ccc2CCCNc2n1)CC[C@H](Nc1nc(C)nc2cc(F)ccc12)C(O)=O
Show InChI InChI=1S/C28H37FN6O3/c1-19-31-25-18-21(29)9-11-23(25)27(32-19)34-24(28(36)37)12-15-35(16-17-38-2)14-4-3-7-22-10-8-20-6-5-13-30-26(20)33-22/h8-11,18,24H,3-7,12-17H2,1-2H3,(H,30,33)(H,36,37)(H,31,32,34)/t24-/m0/s1
PDB

Reactome pathway

UniProtKB/SwissProt

antibodypedia
antibodypedia
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a<50n/an/an/an/an/an/a



PLIANT THERAPEUTICS, INC.

US Patent


Assay Description
Microplates were coated with recombinant human integrin αVβ6 (2 μg/mL) in PBS (100 μL/well 25 C., overnight). The coating soluti...


US Patent US10793564 (2020)

More data for this
Ligand-Target Pair
Integrin alpha-V/alpha-5


(Homo sapiens (Human))
BDBM465234
PNG
(US10793564, Compound 23)
Show SMILES COCCN(CCCCc1ccc2CCCNc2n1)CC[C@H](Nc1cc(ncn1)C(F)F)C(O)=O
Show InChI InChI=1S/C24H34F2N6O3/c1-35-14-13-32(11-3-2-6-18-8-7-17-5-4-10-27-23(17)30-18)12-9-19(24(33)34)31-21-15-20(22(25)26)28-16-29-21/h7-8,15-16,19,22H,2-6,9-14H2,1H3,(H,27,30)(H,33,34)(H,28,29,31)/t19-/m0/s1
PDB

Reactome pathway

UniProtKB/SwissProt

antibodypedia
antibodypedia
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a<50n/an/an/an/an/an/a



PLIANT THERAPEUTICS, INC.

US Patent


Assay Description
Microplates were coated with recombinant human integrin αVβ6 (2 μg/mL) in PBS (100 μL/well 25 C., overnight). The coating soluti...


US Patent US10793564 (2020)

More data for this
Ligand-Target Pair
Integrin alpha-V/alpha-5


(Homo sapiens (Human))
BDBM465235
PNG
(US10793564, Compound 24)
Show SMILES COCCN(CCCCc1ccc2CCCNc2n1)CC[C@H](Nc1ccnc(n1)C(F)(F)F)C(O)=O
Show InChI InChI=1S/C24H33F3N6O3/c1-36-16-15-33(13-3-2-6-18-8-7-17-5-4-11-28-21(17)30-18)14-10-19(22(34)35)31-20-9-12-29-23(32-20)24(25,26)27/h7-9,12,19H,2-6,10-11,13-16H2,1H3,(H,28,30)(H,34,35)(H,29,31,32)/t19-/m0/s1
PDB

Reactome pathway

UniProtKB/SwissProt

antibodypedia
antibodypedia
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a<50n/an/an/an/an/an/a



PLIANT THERAPEUTICS, INC.

US Patent


Assay Description
Microplates were coated with recombinant human integrin αVβ6 (2 μg/mL) in PBS (100 μL/well 25 C., overnight). The coating soluti...


US Patent US10793564 (2020)

More data for this
Ligand-Target Pair
Integrin alpha-V/alpha-5


(Homo sapiens (Human))
BDBM465242
PNG
(US10793564, Compound 31)
Show SMILES COC[C@@H](F)CN(CCCCc1ccc2CCCNc2n1)CC[C@H](Nc1ncnc2ccccc12)C(O)=O
Show InChI InChI=1S/C28H37FN6O3/c1-38-18-21(29)17-35(15-5-4-8-22-12-11-20-7-6-14-30-26(20)33-22)16-13-25(28(36)37)34-27-23-9-2-3-10-24(23)31-19-32-27/h2-3,9-12,19,21,25H,4-8,13-18H2,1H3,(H,30,33)(H,36,37)(H,31,32,34)/t21-,25-/m0/s1
PDB

Reactome pathway

UniProtKB/SwissProt

antibodypedia
antibodypedia
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a<50n/an/an/an/an/an/a



PLIANT THERAPEUTICS, INC.

US Patent


Assay Description
Microplates were coated with recombinant human integrin αVβ6 (2 μg/mL) in PBS (100 μL/well 25 C., overnight). The coating soluti...


US Patent US10793564 (2020)

More data for this
Ligand-Target Pair
Integrin alpha-V/alpha-5


(Homo sapiens (Human))
BDBM465248
PNG
(US10793564, Compound 37)
Show SMILES COCCN(CCCCc1ccc2CCCNc2n1)CC[C@H](Nc1ncnc2cc(Cl)ccc12)C(O)=O
Show InChI InChI=1S/C27H35ClN6O3/c1-37-16-15-34(13-3-2-6-21-9-7-19-5-4-12-29-25(19)32-21)14-11-23(27(35)36)33-26-22-10-8-20(28)17-24(22)30-18-31-26/h7-10,17-18,23H,2-6,11-16H2,1H3,(H,29,32)(H,35,36)(H,30,31,33)/t23-/m0/s1
PDB

Reactome pathway

UniProtKB/SwissProt

antibodypedia
antibodypedia
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 150n/an/an/an/an/an/a



PLIANT THERAPEUTICS, INC.

US Patent


Assay Description
Microplates were coated with recombinant human integrin αVβ6 (2 μg/mL) in PBS (100 μL/well 25 C., overnight). The coating soluti...


US Patent US10793564 (2020)

More data for this
Ligand-Target Pair
Integrin alpha-V/alpha-5


(Homo sapiens (Human))
BDBM465326
PNG
(US10793564, Compound 116)
Show SMILES OC(=O)[C@H](CCN(CCCCc1ccc2CCCNc2n1)C1CC1)Nc1ncnc2[nH]ncc12
Show InChI InChI=1S/C24H32N8O2/c33-24(34)20(30-22-19-14-28-31-23(19)27-15-26-22)10-13-32(18-8-9-18)12-2-1-5-17-7-6-16-4-3-11-25-21(16)29-17/h6-7,14-15,18,20H,1-5,8-13H2,(H,25,29)(H,33,34)(H2,26,27,28,30,31)/t20-/m0/s1
PDB

Reactome pathway

UniProtKB/SwissProt

antibodypedia
antibodypedia
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 150n/an/an/an/an/an/a



PLIANT THERAPEUTICS, INC.

US Patent


Assay Description
Microplates were coated with recombinant human integrin αVβ6 (2 μg/mL) in PBS (100 μL/well 25 C., overnight). The coating soluti...


US Patent US10793564 (2020)

More data for this
Ligand-Target Pair
Integrin alpha-V/alpha-5


(Homo sapiens (Human))
BDBM465219
PNG
(US10793564, Compound 8)
Show SMILES OC(=O)[C@H](CCN(CCCCc1ccc2CCCNc2n1)CC(F)F)Nc1ncnc2ccccc12
Show InChI InChI=1S/C26H32F2N6O2/c27-23(28)16-34(14-4-3-7-19-11-10-18-6-5-13-29-24(18)32-19)15-12-22(26(35)36)33-25-20-8-1-2-9-21(20)30-17-31-25/h1-2,8-11,17,22-23H,3-7,12-16H2,(H,29,32)(H,35,36)(H,30,31,33)/t22-/m0/s1
PDB

Reactome pathway

UniProtKB/SwissProt

antibodypedia
antibodypedia
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 150n/an/an/an/an/an/a



PLIANT THERAPEUTICS, INC.

US Patent


Assay Description
Microplates were coated with recombinant human integrin αVβ6 (2 μg/mL) in PBS (100 μL/well 25 C., overnight). The coating soluti...


US Patent US10793564 (2020)

More data for this
Ligand-Target Pair
Integrin alpha-V/alpha-5


(Homo sapiens (Human))
BDBM465312
PNG
(US10793564, Compound 101)
Show SMILES Cn1ncc2c(N[C@@H](CCN(CCCCc3ccc4CCCNc4n3)CCS(C)(=O)=O)C(O)=O)ncnc12
Show InChI InChI=1S/C25H36N8O4S/c1-32-24-20(16-29-32)23(27-17-28-24)31-21(25(34)35)10-13-33(14-15-38(2,36)37)12-4-3-7-19-9-8-18-6-5-11-26-22(18)30-19/h8-9,16-17,21H,3-7,10-15H2,1-2H3,(H,26,30)(H,34,35)(H,27,28,31)/t21-/m0/s1
PDB

Reactome pathway

UniProtKB/SwissProt

antibodypedia
antibodypedia
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 150n/an/an/an/an/an/a



PLIANT THERAPEUTICS, INC.

US Patent


Assay Description
Microplates were coated with recombinant human integrin αVβ6 (2 μg/mL) in PBS (100 μL/well 25 C., overnight). The coating soluti...


US Patent US10793564 (2020)

More data for this
Ligand-Target Pair
Integrin alpha-V/alpha-5


(Homo sapiens (Human))
BDBM465343
PNG
(US10793564, Compound 133)
Show SMILES Cn1ncc2c(N[C@@H](CCN(CCCCc3ccc4CCCNc4n3)CCC(F)F)C(O)=O)ncnc12
Show InChI InChI=1S/C25H34F2N8O2/c1-34-24-19(15-31-34)23(29-16-30-24)33-20(25(36)37)9-13-35(14-10-21(26)27)12-3-2-6-18-8-7-17-5-4-11-28-22(17)32-18/h7-8,15-16,20-21H,2-6,9-14H2,1H3,(H,28,32)(H,36,37)(H,29,30,33)/t20-/m0/s1
PDB

Reactome pathway

UniProtKB/SwissProt

antibodypedia
antibodypedia
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 150n/an/an/an/an/an/a



PLIANT THERAPEUTICS, INC.

US Patent


Assay Description
Microplates were coated with recombinant human integrin αVβ6 (2 μg/mL) in PBS (100 μL/well 25 C., overnight). The coating soluti...


US Patent US10793564 (2020)

More data for this
Ligand-Target Pair
Integrin alpha-V/alpha-5


(Homo sapiens (Human))
BDBM465345
PNG
(US10793564, Compound 135)
Show SMILES OC(=O)[C@H](CCN(CCCCc1ccc2CCCNc2n1)CCC(F)F)Nc1ncc(cn1)C1CC1
Show InChI InChI=1S/C26H36F2N6O2/c27-23(28)11-15-34(13-2-1-5-21-9-8-19-4-3-12-29-24(19)32-21)14-10-22(25(35)36)33-26-30-16-20(17-31-26)18-6-7-18/h8-9,16-18,22-23H,1-7,10-15H2,(H,29,32)(H,35,36)(H,30,31,33)/t22-/m0/s1
PDB

Reactome pathway

UniProtKB/SwissProt

antibodypedia
antibodypedia
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 150n/an/an/an/an/an/a



PLIANT THERAPEUTICS, INC.

US Patent


Assay Description
Microplates were coated with recombinant human integrin αVβ6 (2 μg/mL) in PBS (100 μL/well 25 C., overnight). The coating soluti...


US Patent US10793564 (2020)

More data for this
Ligand-Target Pair
Integrin alpha-V/alpha-5


(Homo sapiens (Human))
BDBM465357
PNG
(US10793564, Compound 147)
Show SMILES OC(=O)[C@H](CCN(CCCCc1ccc2CCCNc2n1)CC1(F)COC1)Nc1ncnc2ccccc12
Show InChI InChI=1S/C28H35FN6O3/c29-28(17-38-18-28)16-35(14-4-3-7-21-11-10-20-6-5-13-30-25(20)33-21)15-12-24(27(36)37)34-26-22-8-1-2-9-23(22)31-19-32-26/h1-2,8-11,19,24H,3-7,12-18H2,(H,30,33)(H,36,37)(H,31,32,34)/t24-/m0/s1
PDB

Reactome pathway

UniProtKB/SwissProt

antibodypedia
antibodypedia
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 150n/an/an/an/an/an/a



PLIANT THERAPEUTICS, INC.

US Patent


Assay Description
Microplates were coated with recombinant human integrin αVβ6 (2 μg/mL) in PBS (100 μL/well 25 C., overnight). The coating soluti...


US Patent US10793564 (2020)

More data for this
Ligand-Target Pair
Integrin alpha-V/alpha-5


(Homo sapiens (Human))
BDBM465342
PNG
(US10793564, Compound 132)
Show SMILES OC(=O)[C@H](CCN(CCCCc1ccc2CCCNc2n1)CCC(F)F)Nc1ncc(cn1)C(F)(F)F
Show InChI InChI=1S/C24H31F5N6O2/c25-20(26)9-13-35(11-2-1-5-18-7-6-16-4-3-10-30-21(16)33-18)12-8-19(22(36)37)34-23-31-14-17(15-32-23)24(27,28)29/h6-7,14-15,19-20H,1-5,8-13H2,(H,30,33)(H,36,37)(H,31,32,34)/t19-/m0/s1
PDB

Reactome pathway

UniProtKB/SwissProt

antibodypedia
antibodypedia
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 150n/an/an/an/an/an/a



PLIANT THERAPEUTICS, INC.

US Patent


Assay Description
Microplates were coated with recombinant human integrin αVβ6 (2 μg/mL) in PBS (100 μL/well 25 C., overnight). The coating soluti...


US Patent US10793564 (2020)

More data for this
Ligand-Target Pair
Integrin alpha-V/alpha-5


(Homo sapiens (Human))
BDBM465215
PNG
(US10793564, Compound 4)
Show SMILES CC(C)(O)CN(CCCCc1ccc2CCCNc2n1)CC[C@H](Nc1ccncn1)C(O)=O
Show InChI InChI=1S/C24H36N6O3/c1-24(2,33)16-30(15-11-20(23(31)32)29-21-10-13-25-17-27-21)14-4-3-7-19-9-8-18-6-5-12-26-22(18)28-19/h8-10,13,17,20,33H,3-7,11-12,14-16H2,1-2H3,(H,26,28)(H,31,32)(H,25,27,29)/t20-/m0/s1
PDB

Reactome pathway

UniProtKB/SwissProt

antibodypedia
antibodypedia
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 150n/an/an/an/an/an/a



PLIANT THERAPEUTICS, INC.

US Patent


Assay Description
Microplates were coated with recombinant human integrin αVβ6 (2 μg/mL) in PBS (100 μL/well 25 C., overnight). The coating soluti...


US Patent US10793564 (2020)

More data for this
Ligand-Target Pair
Integrin alpha-V/alpha-5


(Homo sapiens (Human))
BDBM465224
PNG
(US10793564, Compound 13)
Show SMILES COCCN(CCCCc1ccc2CCCNc2n1)CC[C@H](Nc1ncnc2cc(ccc12)C(F)(F)F)C(O)=O
Show InChI InChI=1S/C28H35F3N6O3/c1-40-16-15-37(13-3-2-6-21-9-7-19-5-4-12-32-25(19)35-21)14-11-23(27(38)39)36-26-22-10-8-20(28(29,30)31)17-24(22)33-18-34-26/h7-10,17-18,23H,2-6,11-16H2,1H3,(H,32,35)(H,38,39)(H,33,34,36)/t23-/m0/s1
PDB

Reactome pathway

UniProtKB/SwissProt

antibodypedia
antibodypedia
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 150n/an/an/an/an/an/a



PLIANT THERAPEUTICS, INC.

US Patent


Assay Description
Microplates were coated with recombinant human integrin αVβ6 (2 μg/mL) in PBS (100 μL/well 25 C., overnight). The coating soluti...


US Patent US10793564 (2020)

More data for this
Ligand-Target Pair
Integrin alpha-V/alpha-5


(Homo sapiens (Human))
BDBM465341
PNG
(US10793564, Compound 131)
Show SMILES OC(=O)[C@H](CCN(CCCCc1ccc2CCCNc2n1)CCC(F)F)Nc1ncc(Br)cn1
Show InChI InChI=1S/C23H31BrF2N6O2/c24-17-14-28-23(29-15-17)31-19(22(33)34)8-12-32(13-9-20(25)26)11-2-1-5-18-7-6-16-4-3-10-27-21(16)30-18/h6-7,14-15,19-20H,1-5,8-13H2,(H,27,30)(H,33,34)(H,28,29,31)/t19-/m0/s1
PDB

Reactome pathway

UniProtKB/SwissProt

antibodypedia
antibodypedia
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 150n/an/an/an/an/an/a



PLIANT THERAPEUTICS, INC.

US Patent


Assay Description
Microplates were coated with recombinant human integrin αVβ6 (2 μg/mL) in PBS (100 μL/well 25 C., overnight). The coating soluti...


US Patent US10793564 (2020)

More data for this
Ligand-Target Pair
Integrin alpha-V/alpha-5


(Homo sapiens (Human))
BDBM465354
PNG
(US10793564, Compound 144)
Show SMILES OC(=O)[C@H](CCN(CCCCc1ccc2CCCNc2n1)CCOc1ccc(F)cc1)Nc1ncc(Br)cn1
Show InChI InChI=1S/C28H34BrFN6O3/c29-21-18-32-28(33-19-21)35-25(27(37)38)12-15-36(16-17-39-24-10-7-22(30)8-11-24)14-2-1-5-23-9-6-20-4-3-13-31-26(20)34-23/h6-11,18-19,25H,1-5,12-17H2,(H,31,34)(H,37,38)(H,32,33,35)/t25-/m0/s1
PDB

Reactome pathway

UniProtKB/SwissProt

antibodypedia
antibodypedia
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 150n/an/an/an/an/an/a



PLIANT THERAPEUTICS, INC.

US Patent


Assay Description
Microplates were coated with recombinant human integrin αVβ6 (2 μg/mL) in PBS (100 μL/well 25 C., overnight). The coating soluti...


US Patent US10793564 (2020)

More data for this
Ligand-Target Pair
Integrin alpha-V/alpha-5


(Homo sapiens (Human))
BDBM465217
PNG
(US10793564, Compound 6)
Show SMILES OC(=O)[C@H](CCN(CCCCc1ccc2CCCNc2n1)C1CC1)Nc1ncnc2ccccc12
Show InChI InChI=1S/C27H34N6O2/c34-27(35)24(32-26-22-8-1-2-9-23(22)29-18-30-26)14-17-33(21-12-13-21)16-4-3-7-20-11-10-19-6-5-15-28-25(19)31-20/h1-2,8-11,18,21,24H,3-7,12-17H2,(H,28,31)(H,34,35)(H,29,30,32)/t24-/m0/s1
PDB

Reactome pathway

UniProtKB/SwissProt

antibodypedia
antibodypedia
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 150n/an/an/an/an/an/a



PLIANT THERAPEUTICS, INC.

US Patent


Assay Description
Microplates were coated with recombinant human integrin αVβ6 (2 μg/mL) in PBS (100 μL/well 25 C., overnight). The coating soluti...


US Patent US10793564 (2020)

More data for this
Ligand-Target Pair
Integrin alpha-V/alpha-5


(Homo sapiens (Human))
BDBM465325
PNG
(US10793564, Compound 115)
Show SMILES OC(=O)[C@H](CCN(CCCCc1ccc2CCCNc2n1)C1CC1)Nc1ccnc(n1)C(F)(F)F
Show InChI InChI=1S/C24H31F3N6O2/c25-24(26,27)23-29-13-10-20(32-23)31-19(22(34)35)11-15-33(18-8-9-18)14-2-1-5-17-7-6-16-4-3-12-28-21(16)30-17/h6-7,10,13,18-19H,1-5,8-9,11-12,14-15H2,(H,28,30)(H,34,35)(H,29,31,32)/t19-/m0/s1
PDB

Reactome pathway

UniProtKB/SwissProt

antibodypedia
antibodypedia
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 150n/an/an/an/an/an/a



PLIANT THERAPEUTICS, INC.

US Patent


Assay Description
Microplates were coated with recombinant human integrin αVβ6 (2 μg/mL) in PBS (100 μL/well 25 C., overnight). The coating soluti...


US Patent US10793564 (2020)

More data for this
Ligand-Target Pair
Integrin alpha-V/alpha-5


(Homo sapiens (Human))
BDBM465335
PNG
(US10793564, Compound 125)
Show SMILES CS(=O)(=O)CCN(CCCCc1ccc2CCCNc2n1)CC[C@H](Nc1ncnc2[nH]ncc12)C(O)=O
Show InChI InChI=1S/C24H34N8O4S/c1-37(35,36)14-13-32(11-3-2-6-18-8-7-17-5-4-10-25-21(17)29-18)12-9-20(24(33)34)30-22-19-15-28-31-23(19)27-16-26-22/h7-8,15-16,20H,2-6,9-14H2,1H3,(H,25,29)(H,33,34)(H2,26,27,28,30,31)/t20-/m0/s1
PDB

Reactome pathway

UniProtKB/SwissProt

antibodypedia
antibodypedia
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 150n/an/an/an/an/an/a



PLIANT THERAPEUTICS, INC.

US Patent


Assay Description
Microplates were coated with recombinant human integrin αVβ6 (2 μg/mL) in PBS (100 μL/well 25 C., overnight). The coating soluti...


US Patent US10793564 (2020)

More data for this
Ligand-Target Pair
Integrin alpha-V/alpha-5


(Homo sapiens (Human))
BDBM465297
PNG
(US10793564, Compound 86)
Show SMILES COC[C@@H](F)CN(CCCCc1ccc2CCCNc2n1)CC[C@H](Nc1ncc(Br)cn1)C(O)=O
Show InChI InChI=1S/C24H34BrFN6O3/c1-35-16-19(26)15-32(12-9-21(23(33)34)31-24-28-13-18(25)14-29-24)11-3-2-6-20-8-7-17-5-4-10-27-22(17)30-20/h7-8,13-14,19,21H,2-6,9-12,15-16H2,1H3,(H,27,30)(H,33,34)(H,28,29,31)/t19-,21-/m0/s1
PDB

Reactome pathway

UniProtKB/SwissProt

antibodypedia
antibodypedia
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 150n/an/an/an/an/an/a



PLIANT THERAPEUTICS, INC.

US Patent


Assay Description
Microplates were coated with recombinant human integrin αVβ6 (2 μg/mL) in PBS (100 μL/well 25 C., overnight). The coating soluti...


US Patent US10793564 (2020)

More data for this
Ligand-Target Pair
Integrin alpha-V/alpha-5


(Homo sapiens (Human))
BDBM465344
PNG
(US10793564, Compound 134)
Show SMILES OC(=O)[C@H](CCN(CCCCc1ccc2CCCNc2n1)CCC(F)F)Nc1ccnc(n1)C(F)(F)F
Show InChI InChI=1S/C24H31F5N6O2/c25-19(26)10-15-35(13-2-1-5-17-7-6-16-4-3-11-30-21(16)32-17)14-9-18(22(36)37)33-20-8-12-31-23(34-20)24(27,28)29/h6-8,12,18-19H,1-5,9-11,13-15H2,(H,30,32)(H,36,37)(H,31,33,34)/t18-/m0/s1
PDB

Reactome pathway

UniProtKB/SwissProt

antibodypedia
antibodypedia
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 150n/an/an/an/an/an/a



PLIANT THERAPEUTICS, INC.

US Patent


Assay Description
Microplates were coated with recombinant human integrin αVβ6 (2 μg/mL) in PBS (100 μL/well 25 C., overnight). The coating soluti...


US Patent US10793564 (2020)

More data for this
Ligand-Target Pair
Integrin alpha-V/alpha-5


(Homo sapiens (Human))
BDBM465351
PNG
(US10793564, Compound 141)
Show SMILES CN(C)C(=O)CN(CCCCc1ccc2CCCNc2n1)CC[C@H](Nc1ncc(cn1)C(F)(F)F)C(O)=O
Show InChI InChI=1S/C25H34F3N7O3/c1-34(2)21(36)16-35(12-4-3-7-19-9-8-17-6-5-11-29-22(17)32-19)13-10-20(23(37)38)33-24-30-14-18(15-31-24)25(26,27)28/h8-9,14-15,20H,3-7,10-13,16H2,1-2H3,(H,29,32)(H,37,38)(H,30,31,33)/t20-/m0/s1
PDB

Reactome pathway

UniProtKB/SwissProt

antibodypedia
antibodypedia
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 150n/an/an/an/an/an/a



PLIANT THERAPEUTICS, INC.

US Patent


Assay Description
Microplates were coated with recombinant human integrin αVβ6 (2 μg/mL) in PBS (100 μL/well 25 C., overnight). The coating soluti...


US Patent US10793564 (2020)

More data for this
Ligand-Target Pair
Integrin alpha-V/alpha-5


(Homo sapiens (Human))
BDBM465353
PNG
(US10793564, Compound 143)
Show SMILES OC(=O)[C@H](CCN(CCCCc1ccc2CCCNc2n1)CCOc1ccc(F)cc1)Nc1ncnc2[nH]ncc12
Show InChI InChI=1S/C29H35FN8O3/c30-21-7-10-23(11-8-21)41-17-16-38(14-2-1-5-22-9-6-20-4-3-13-31-26(20)35-22)15-12-25(29(39)40)36-27-24-18-34-37-28(24)33-19-32-27/h6-11,18-19,25H,1-5,12-17H2,(H,31,35)(H,39,40)(H2,32,33,34,36,37)/t25-/m0/s1
PDB

Reactome pathway

UniProtKB/SwissProt

antibodypedia
antibodypedia
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 150n/an/an/an/an/an/a



PLIANT THERAPEUTICS, INC.

US Patent


Assay Description
Microplates were coated with recombinant human integrin αVβ6 (2 μg/mL) in PBS (100 μL/well 25 C., overnight). The coating soluti...


US Patent US10793564 (2020)

More data for this
Ligand-Target Pair
Integrin alpha-V/alpha-5


(Homo sapiens (Human))
BDBM465214
PNG
(US10793564, Compound 2)
Show SMILES OC(=O)[C@H](CCN(CCCCc1ccc2CCCNc2n1)C1CC1)Nc1ccncn1
Show InChI InChI=1S/C23H32N6O2/c30-23(31)20(28-21-10-13-24-16-26-21)11-15-29(19-8-9-19)14-2-1-5-18-7-6-17-4-3-12-25-22(17)27-18/h6-7,10,13,16,19-20H,1-5,8-9,11-12,14-15H2,(H,25,27)(H,30,31)(H,24,26,28)/t20-/m0/s1
PDB

Reactome pathway

UniProtKB/SwissProt

antibodypedia
antibodypedia
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 625n/an/an/an/an/an/a



PLIANT THERAPEUTICS, INC.

US Patent


Assay Description
Microplates were coated with recombinant human integrin αVβ6 (2 μg/mL) in PBS (100 μL/well 25 C., overnight). The coating soluti...


US Patent US10793564 (2020)

More data for this
Ligand-Target Pair
Integrin alpha-V/alpha-5


(Homo sapiens (Human))
BDBM465296
PNG
(US10793564, Compound 85)
Show SMILES COC[C@@H](F)CN(CCCCc1ccc2CCCNc2n1)CC[C@H](Nc1ncc(cn1)C(F)(F)F)C(O)=O
Show InChI InChI=1S/C25H34F4N6O3/c1-38-16-19(26)15-35(11-3-2-6-20-8-7-17-5-4-10-30-22(17)33-20)12-9-21(23(36)37)34-24-31-13-18(14-32-24)25(27,28)29/h7-8,13-14,19,21H,2-6,9-12,15-16H2,1H3,(H,30,33)(H,36,37)(H,31,32,34)/t19-,21-/m0/s1
PDB

Reactome pathway

UniProtKB/SwissProt

antibodypedia
antibodypedia
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 625n/an/an/an/an/an/a



PLIANT THERAPEUTICS, INC.

US Patent


Assay Description
Microplates were coated with recombinant human integrin αVβ6 (2 μg/mL) in PBS (100 μL/well 25 C., overnight). The coating soluti...


US Patent US10793564 (2020)

More data for this
Ligand-Target Pair
Integrin alpha-V/alpha-5


(Homo sapiens (Human))
BDBM465295
PNG
(US10793564, Compound 84)
Show SMILES COC[C@@H](F)CN(CCCCc1ccc2CCCNc2n1)CC[C@H](Nc1ncc(cn1)C#N)C(O)=O
Show InChI InChI=1S/C25H34FN7O3/c1-36-17-20(26)16-33(11-3-2-6-21-8-7-19-5-4-10-28-23(19)31-21)12-9-22(24(34)35)32-25-29-14-18(13-27)15-30-25/h7-8,14-15,20,22H,2-6,9-12,16-17H2,1H3,(H,28,31)(H,34,35)(H,29,30,32)/t20-,22-/m0/s1
PDB

Reactome pathway

UniProtKB/SwissProt

antibodypedia
antibodypedia
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 625n/an/an/an/an/an/a



PLIANT THERAPEUTICS, INC.

US Patent


Assay Description
Microplates were coated with recombinant human integrin αVβ6 (2 μg/mL) in PBS (100 μL/well 25 C., overnight). The coating soluti...


US Patent US10793564 (2020)

More data for this
Ligand-Target Pair
Integrin alpha-V/alpha-5


(Homo sapiens (Human))
BDBM465337
PNG
(US10793564, Compound 127)
Show SMILES COC[C@@H](F)CN(CCCCc1ccc2CCCNc2n1)CC[C@H](Nc1ccncn1)C(O)=O
Show InChI InChI=1S/C24H35FN6O3/c1-34-16-19(25)15-31(14-10-21(24(32)33)30-22-9-12-26-17-28-22)13-3-2-6-20-8-7-18-5-4-11-27-23(18)29-20/h7-9,12,17,19,21H,2-6,10-11,13-16H2,1H3,(H,27,29)(H,32,33)(H,26,28,30)/t19-,21-/m0/s1
PDB

Reactome pathway

UniProtKB/SwissProt

antibodypedia
antibodypedia
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 625n/an/an/an/an/an/a



PLIANT THERAPEUTICS, INC.

US Patent


Assay Description
Microplates were coated with recombinant human integrin αVβ6 (2 μg/mL) in PBS (100 μL/well 25 C., overnight). The coating soluti...


US Patent US10793564 (2020)

More data for this
Ligand-Target Pair
Integrin alpha-V/alpha-5


(Homo sapiens (Human))
BDBM465323
PNG
(US10793564, Compound 112)
Show SMILES OC(=O)[C@H](CCN(CCCCc1ccc2CCCNc2n1)CC(F)F)Nc1ncnc2[nH]ncc12
Show InChI InChI=1S/C23H30F2N8O2/c24-19(25)13-33(10-2-1-5-16-7-6-15-4-3-9-26-20(15)30-16)11-8-18(23(34)35)31-21-17-12-29-32-22(17)28-14-27-21/h6-7,12,14,18-19H,1-5,8-11,13H2,(H,26,30)(H,34,35)(H2,27,28,29,31,32)/t18-/m0/s1
PDB

Reactome pathway

UniProtKB/SwissProt

antibodypedia
antibodypedia
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 625n/an/an/an/an/an/a



PLIANT THERAPEUTICS, INC.

US Patent


Assay Description
Microplates were coated with recombinant human integrin αVβ6 (2 μg/mL) in PBS (100 μL/well 25 C., overnight). The coating soluti...


US Patent US10793564 (2020)

More data for this
Ligand-Target Pair
Integrin alpha-V/alpha-5


(Homo sapiens (Human))
BDBM465332
PNG
(US10793564, Compound 122)
Show SMILES Cc1cc(N[C@@H](CCN(CCCCc2ccc3CCCNc3n2)CC(F)F)C(O)=O)nc(n1)-c1ccncc1
Show InChI InChI=1S/C28H35F2N7O2/c1-19-17-25(36-27(33-19)21-9-13-31-14-10-21)35-23(28(38)39)11-16-37(18-24(29)30)15-3-2-6-22-8-7-20-5-4-12-32-26(20)34-22/h7-10,13-14,17,23-24H,2-6,11-12,15-16,18H2,1H3,(H,32,34)(H,38,39)(H,33,35,36)/t23-/m0/s1
PDB

Reactome pathway

UniProtKB/SwissProt

antibodypedia
antibodypedia
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 625n/an/an/an/an/an/a



PLIANT THERAPEUTICS, INC.

US Patent


Assay Description
Microplates were coated with recombinant human integrin αVβ6 (2 μg/mL) in PBS (100 μL/well 25 C., overnight). The coating soluti...


US Patent US10793564 (2020)

More data for this
Ligand-Target Pair
Integrin alpha-V/alpha-5


(Homo sapiens (Human))
BDBM465298
PNG
(US10793564, Compound 87)
Show SMILES COC[C@@H](F)CN(CCCCc1ccc2CCCNc2n1)CC[C@H](Nc1ccnc(n1)C(F)(F)F)C(O)=O
Show InChI InChI=1S/C25H34F4N6O3/c1-38-16-18(26)15-35(13-3-2-6-19-8-7-17-5-4-11-30-22(17)32-19)14-10-20(23(36)37)33-21-9-12-31-24(34-21)25(27,28)29/h7-9,12,18,20H,2-6,10-11,13-16H2,1H3,(H,30,32)(H,36,37)(H,31,33,34)/t18-,20-/m0/s1
PDB

Reactome pathway

UniProtKB/SwissProt

antibodypedia
antibodypedia
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 625n/an/an/an/an/an/a



PLIANT THERAPEUTICS, INC.

US Patent


Assay Description
Microplates were coated with recombinant human integrin αVβ6 (2 μg/mL) in PBS (100 μL/well 25 C., overnight). The coating soluti...


US Patent US10793564 (2020)

More data for this
Ligand-Target Pair
Integrin alpha-V/alpha-5


(Homo sapiens (Human))
BDBM465310
PNG
(US10793564, Compound 99)
Show SMILES OC(=O)[C@H](CCN(CCCCc1ccc2CCCNc2n1)CC(F)F)Nc1nc(nc2ccccc12)-c1cccnc1
Show InChI InChI=1S/C31H35F2N7O2/c32-27(33)20-40(17-4-3-9-23-13-12-21-7-6-16-35-28(21)36-23)18-14-26(31(41)42)38-30-24-10-1-2-11-25(24)37-29(39-30)22-8-5-15-34-19-22/h1-2,5,8,10-13,15,19,26-27H,3-4,6-7,9,14,16-18,20H2,(H,35,36)(H,41,42)(H,37,38,39)/t26-/m0/s1
PDB

Reactome pathway

UniProtKB/SwissProt

antibodypedia
antibodypedia
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 625n/an/an/an/an/an/a



PLIANT THERAPEUTICS, INC.

US Patent


Assay Description
Microplates were coated with recombinant human integrin αVβ6 (2 μg/mL) in PBS (100 μL/well 25 C., overnight). The coating soluti...


US Patent US10793564 (2020)

More data for this
Ligand-Target Pair
Integrin alpha-V/alpha-5


(Homo sapiens (Human))
BDBM465213
PNG
(US10793564, Compound 1)
Show SMILES OC(=O)[C@H](CCN(CCCCc1ccc2CCCNc2n1)C1CC1)Nc1cc(ncn1)C(F)F
Show InChI InChI=1S/C24H32F2N6O2/c25-22(26)20-14-21(29-15-28-20)31-19(24(33)34)10-13-32(18-8-9-18)12-2-1-5-17-7-6-16-4-3-11-27-23(16)30-17/h6-7,14-15,18-19,22H,1-5,8-13H2,(H,27,30)(H,33,34)(H,28,29,31)/t19-/m0/s1
PDB

Reactome pathway

UniProtKB/SwissProt

antibodypedia
antibodypedia
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 625n/an/an/an/an/an/a



PLIANT THERAPEUTICS, INC.

US Patent


Assay Description
Microplates were coated with recombinant human integrin αVβ6 (2 μg/mL) in PBS (100 μL/well 25 C., overnight). The coating soluti...


US Patent US10793564 (2020)

More data for this
Ligand-Target Pair
Integrin alpha-V/alpha-5


(Homo sapiens (Human))
BDBM465318
PNG
(US10793564, Compound 107)
Show SMILES CS(=O)(=O)CCN(CCCCc1ccc2CCCNc2n1)CC[C@H](Nc1nc(nc2ccccc12)-c1cccnc1)C(O)=O
Show InChI InChI=1S/C32H39N7O4S/c1-44(42,43)21-20-39(18-5-4-10-25-14-13-23-8-7-17-34-29(23)35-25)19-15-28(32(40)41)37-31-26-11-2-3-12-27(26)36-30(38-31)24-9-6-16-33-22-24/h2-3,6,9,11-14,16,22,28H,4-5,7-8,10,15,17-21H2,1H3,(H,34,35)(H,40,41)(H,36,37,38)/t28-/m0/s1
PDB

Reactome pathway

UniProtKB/SwissProt

antibodypedia
antibodypedia
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 625n/an/an/an/an/an/a



PLIANT THERAPEUTICS, INC.

US Patent


Assay Description
Microplates were coated with recombinant human integrin αVβ6 (2 μg/mL) in PBS (100 μL/well 25 C., overnight). The coating soluti...


US Patent US10793564 (2020)

More data for this
Ligand-Target Pair
Integrin alpha-V/alpha-5


(Homo sapiens (Human))
BDBM465245
PNG
(US10793564, Compound 34)
Show SMILES COCCN(CCCCc1ccc2CCCNc2n1)CC[C@H](Nc1nccc2ccccc12)C(O)=O
Show InChI InChI=1S/C28H37N5O3/c1-36-20-19-33(17-5-4-9-23-12-11-22-8-6-15-29-26(22)31-23)18-14-25(28(34)35)32-27-24-10-3-2-7-21(24)13-16-30-27/h2-3,7,10-13,16,25H,4-6,8-9,14-15,17-20H2,1H3,(H,29,31)(H,30,32)(H,34,35)/t25-/m0/s1
PDB

Reactome pathway

UniProtKB/SwissProt

antibodypedia
antibodypedia
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a>1.00E+3n/an/an/an/an/an/a



PLIANT THERAPEUTICS, INC.

US Patent


Assay Description
Microplates were coated with recombinant human integrin αVβ6 (2 μg/mL) in PBS (100 μL/well 25 C., overnight). The coating soluti...


US Patent US10793564 (2020)

More data for this
Ligand-Target Pair
Integrin alpha-V/alpha-5


(Homo sapiens (Human))
BDBM465309
PNG
(US10793564, Compound 98)
Show SMILES OC(=O)[C@H](CCN(CCCCc1ccc2CCCNc2n1)CC(F)F)Nc1cc(ncn1)-n1cccn1
Show InChI InChI=1S/C25H32F2N8O2/c26-21(27)16-34(12-2-1-6-19-8-7-18-5-3-10-28-24(18)32-19)14-9-20(25(36)37)33-22-15-23(30-17-29-22)35-13-4-11-31-35/h4,7-8,11,13,15,17,20-21H,1-3,5-6,9-10,12,14,16H2,(H,28,32)(H,36,37)(H,29,30,33)/t20-/m0/s1
PDB

Reactome pathway

UniProtKB/SwissProt

antibodypedia
antibodypedia
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a>1.00E+3n/an/an/an/an/an/a



PLIANT THERAPEUTICS, INC.

US Patent


Assay Description
Microplates were coated with recombinant human integrin αVβ6 (2 μg/mL) in PBS (100 μL/well 25 C., overnight). The coating soluti...


US Patent US10793564 (2020)

More data for this
Ligand-Target Pair
Integrin alpha-V/alpha-5


(Homo sapiens (Human))
BDBM465315
PNG
(US10793564, Compound 104)
Show SMILES CS(=O)(=O)CCN(CCCCc1ccc2CCCNc2n1)CC[C@H](Nc1ccnc(n1)C(F)(F)F)C(O)=O
Show InChI InChI=1S/C24H33F3N6O4S/c1-38(36,37)16-15-33(13-3-2-6-18-8-7-17-5-4-11-28-21(17)30-18)14-10-19(22(34)35)31-20-9-12-29-23(32-20)24(25,26)27/h7-9,12,19H,2-6,10-11,13-16H2,1H3,(H,28,30)(H,34,35)(H,29,31,32)/t19-/m0/s1
PDB

Reactome pathway

UniProtKB/SwissProt

antibodypedia
antibodypedia
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a>1.00E+3n/an/an/an/an/an/a



PLIANT THERAPEUTICS, INC.

US Patent


Assay Description
Microplates were coated with recombinant human integrin αVβ6 (2 μg/mL) in PBS (100 μL/well 25 C., overnight). The coating soluti...


US Patent US10793564 (2020)

More data for this
Ligand-Target Pair
Integrin alpha-V/alpha-5


(Homo sapiens (Human))
BDBM465328
PNG
(US10793564, Compound 118)
Show SMILES OC(=O)[C@H](CCN(CCCCc1ccc2CCCNc2n1)CC(F)F)Nc1ncc(cn1)C#N
Show InChI InChI=1S/C23H29F2N7O2/c24-20(25)15-32(10-2-1-5-18-7-6-17-4-3-9-27-21(17)30-18)11-8-19(22(33)34)31-23-28-13-16(12-26)14-29-23/h6-7,13-14,19-20H,1-5,8-11,15H2,(H,27,30)(H,33,34)(H,28,29,31)/t19-/m0/s1
PDB

Reactome pathway

UniProtKB/SwissProt

antibodypedia
antibodypedia
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a>1.00E+3n/an/an/an/an/an/a



PLIANT THERAPEUTICS, INC.

US Patent


Assay Description
Microplates were coated with recombinant human integrin αVβ6 (2 μg/mL) in PBS (100 μL/well 25 C., overnight). The coating soluti...


US Patent US10793564 (2020)

More data for this
Ligand-Target Pair
Integrin alpha-V/alpha-5


(Homo sapiens (Human))
BDBM465338
PNG
(US10793564, Compound 128)
Show SMILES COC[C@@H](F)CN(CCCCc1ccc2CCCNc2n1)CC[C@H](Nc1cc(ncn1)-c1ccccc1)C(O)=O
Show InChI InChI=1S/C30H39FN6O3/c1-40-20-24(31)19-37(16-6-5-11-25-13-12-23-10-7-15-32-29(23)35-25)17-14-26(30(38)39)36-28-18-27(33-21-34-28)22-8-3-2-4-9-22/h2-4,8-9,12-13,18,21,24,26H,5-7,10-11,14-17,19-20H2,1H3,(H,32,35)(H,38,39)(H,33,34,36)/t24-,26-/m0/s1
PDB

Reactome pathway

UniProtKB/SwissProt

antibodypedia
antibodypedia
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a>1.00E+3n/an/an/an/an/an/a



PLIANT THERAPEUTICS, INC.

US Patent


Assay Description
Microplates were coated with recombinant human integrin αVβ6 (2 μg/mL) in PBS (100 μL/well 25 C., overnight). The coating soluti...


US Patent US10793564 (2020)

More data for this
Ligand-Target Pair
Integrin alpha-V/alpha-5


(Homo sapiens (Human))
BDBM465356
PNG
((S)-2-((5-cyclopropylpyrimidin-2-yl) amino)-4-((2,...)
Show SMILES OC(=O)[C@H](CCN(CCCCc1ccc2CCCNc2n1)CC(F)F)Nc1ncc(cn1)C1CC1
Show InChI InChI=1S/C25H34F2N6O2/c26-22(27)16-33(12-2-1-5-20-9-8-18-4-3-11-28-23(18)31-20)13-10-21(24(34)35)32-25-29-14-19(15-30-25)17-6-7-17/h8-9,14-15,17,21-22H,1-7,10-13,16H2,(H,28,31)(H,34,35)(H,29,30,32)/t21-/m0/s1
PDB

Reactome pathway

UniProtKB/SwissProt

antibodypedia
antibodypedia
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a>1.00E+3n/an/an/an/an/an/a



PLIANT THERAPEUTICS, INC.

US Patent


Assay Description
Microplates were coated with recombinant human integrin αVβ6 (2 μg/mL) in PBS (100 μL/well 25 C., overnight). The coating soluti...


US Patent US10793564 (2020)

More data for this
Ligand-Target Pair
Integrin alpha-V/alpha-5


(Homo sapiens (Human))
BDBM465247
PNG
(US10793564, Compound 36)
Show SMILES COCCN(CCCCc1ccc2CCCNc2n1)CC[C@H](Nc1ccnc2ccccc12)C(O)=O
Show InChI InChI=1S/C28H37N5O3/c1-36-20-19-33(17-5-4-8-22-12-11-21-7-6-15-30-27(21)31-22)18-14-26(28(34)35)32-25-13-16-29-24-10-3-2-9-23(24)25/h2-3,9-13,16,26H,4-8,14-15,17-20H2,1H3,(H,29,32)(H,30,31)(H,34,35)/t26-/m0/s1
PDB

Reactome pathway

UniProtKB/SwissProt

antibodypedia
antibodypedia
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a>1.00E+3n/an/an/an/an/an/a



PLIANT THERAPEUTICS, INC.

US Patent


Assay Description
Microplates were coated with recombinant human integrin αVβ6 (2 μg/mL) in PBS (100 μL/well 25 C., overnight). The coating soluti...


US Patent US10793564 (2020)

More data for this
Ligand-Target Pair
Integrin alpha-V/alpha-5


(Homo sapiens (Human))
BDBM465331
PNG
(US10793564, Compound 121)
Show SMILES OC(=O)[C@H](CCN(CCCCc1ccc2CCCNc2n1)CC(F)F)Nc1ncc(F)cn1
Show InChI InChI=1S/C22H29F3N6O2/c23-16-12-27-22(28-13-16)30-18(21(32)33)8-11-31(14-19(24)25)10-2-1-5-17-7-6-15-4-3-9-26-20(15)29-17/h6-7,12-13,18-19H,1-5,8-11,14H2,(H,26,29)(H,32,33)(H,27,28,30)/t18-/m0/s1
PDB

Reactome pathway

UniProtKB/SwissProt

antibodypedia
antibodypedia
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a>1.00E+3n/an/an/an/an/an/a



PLIANT THERAPEUTICS, INC.

US Patent


Assay Description
Microplates were coated with recombinant human integrin αVβ6 (2 μg/mL) in PBS (100 μL/well 25 C., overnight). The coating soluti...


US Patent US10793564 (2020)

More data for this
Ligand-Target Pair
Integrin alpha-V/alpha-5


(Homo sapiens (Human))
BDBM465319
PNG
(US10793564, Compound 108)
Show SMILES COC[C@@H](F)CN(CCCCc1ccc2CCCNc2n1)CC[C@H](Nc1cc(ncn1)-n1cccn1)C(O)=O
Show InChI InChI=1S/C27H37FN8O3/c1-39-18-21(28)17-35(13-3-2-7-22-9-8-20-6-4-11-29-26(20)33-22)15-10-23(27(37)38)34-24-16-25(31-19-30-24)36-14-5-12-32-36/h5,8-9,12,14,16,19,21,23H,2-4,6-7,10-11,13,15,17-18H2,1H3,(H,29,33)(H,37,38)(H,30,31,34)/t21-,23-/m0/s1
PDB

Reactome pathway

UniProtKB/SwissProt

antibodypedia
antibodypedia
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a>1.00E+3n/an/an/an/an/an/a



PLIANT THERAPEUTICS, INC.

US Patent


Assay Description
Microplates were coated with recombinant human integrin αVβ6 (2 μg/mL) in PBS (100 μL/well 25 C., overnight). The coating soluti...


US Patent US10793564 (2020)

More data for this
Ligand-Target Pair
Integrin alpha-V/alpha-5


(Homo sapiens (Human))
BDBM465329
PNG
(US10793564, Compound 119)
Show SMILES OC(=O)[C@H](CCN(CCCCc1ccc2CCCNc2n1)CC(F)F)Nc1ncncc1-c1ccccc1
Show InChI InChI=1S/C28H34F2N6O2/c29-25(30)18-36(15-5-4-10-22-12-11-21-9-6-14-32-26(21)34-22)16-13-24(28(37)38)35-27-23(17-31-19-33-27)20-7-2-1-3-8-20/h1-3,7-8,11-12,17,19,24-25H,4-6,9-10,13-16,18H2,(H,32,34)(H,37,38)(H,31,33,35)/t24-/m0/s1
PDB

Reactome pathway

UniProtKB/SwissProt

antibodypedia
antibodypedia
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a>1.00E+3n/an/an/an/an/an/a



PLIANT THERAPEUTICS, INC.

US Patent


Assay Description
Microplates were coated with recombinant human integrin αVβ6 (2 μg/mL) in PBS (100 μL/well 25 C., overnight). The coating soluti...


US Patent US10793564 (2020)

More data for this
Ligand-Target Pair
Integrin alpha-V/alpha-5


(Homo sapiens (Human))
BDBM465299
PNG
(US10793564, Compound 88)
Show SMILES Cn1ncc2c(N[C@@H](CCN(CCCCc3ccc4CCCNc4n3)CC(F)F)C(O)=O)ncnc12
Show InChI InChI=1S/C24H32F2N8O2/c1-33-23-18(13-30-33)22(28-15-29-23)32-19(24(35)36)9-12-34(14-20(25)26)11-3-2-6-17-8-7-16-5-4-10-27-21(16)31-17/h7-8,13,15,19-20H,2-6,9-12,14H2,1H3,(H,27,31)(H,35,36)(H,28,29,32)/t19-/m0/s1
PDB

Reactome pathway

UniProtKB/SwissProt

antibodypedia
antibodypedia
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a>1.00E+3n/an/an/an/an/an/a



PLIANT THERAPEUTICS, INC.

US Patent


Assay Description
Microplates were coated with recombinant human integrin αVβ6 (2 μg/mL) in PBS (100 μL/well 25 C., overnight). The coating soluti...


US Patent US10793564 (2020)

More data for this
Ligand-Target Pair
Integrin alpha-V/alpha-5


(Homo sapiens (Human))
BDBM465220
PNG
(US10793564, Compound 9)
Show SMILES OC(=O)[C@H](CCN(CCCCc1ccc2CCCNc2n1)C1CC(F)(F)C1)Nc1ncnc2ccccc12
Show InChI InChI=1S/C28H34F2N6O2/c29-28(30)16-21(17-28)36(14-4-3-7-20-11-10-19-6-5-13-31-25(19)34-20)15-12-24(27(37)38)35-26-22-8-1-2-9-23(22)32-18-33-26/h1-2,8-11,18,21,24H,3-7,12-17H2,(H,31,34)(H,37,38)(H,32,33,35)/t24-/m0/s1
PDB

Reactome pathway

UniProtKB/SwissProt

antibodypedia
antibodypedia
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a>1.00E+3n/an/an/an/an/an/a



PLIANT THERAPEUTICS, INC.

US Patent


Assay Description
Microplates were coated with recombinant human integrin αVβ6 (2 μg/mL) in PBS (100 μL/well 25 C., overnight). The coating soluti...


US Patent US10793564 (2020)

More data for this
Ligand-Target Pair
Integrin alpha-V/alpha-5


(Homo sapiens (Human))
BDBM465336
PNG
(US10793564, Compound 126)
Show SMILES CS(=O)(=O)CCN(CCCCc1ccc2CCCNc2n1)CC[C@H](Nc1cc(ncn1)-n1cccn1)C(O)=O
Show InChI InChI=1S/C26H36N8O4S/c1-39(37,38)17-16-33(13-3-2-7-21-9-8-20-6-4-11-27-25(20)31-21)15-10-22(26(35)36)32-23-18-24(29-19-28-23)34-14-5-12-30-34/h5,8-9,12,14,18-19,22H,2-4,6-7,10-11,13,15-17H2,1H3,(H,27,31)(H,35,36)(H,28,29,32)/t22-/m0/s1
PDB

Reactome pathway

UniProtKB/SwissProt

antibodypedia
antibodypedia
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a>1.00E+3n/an/an/an/an/an/a



PLIANT THERAPEUTICS, INC.

US Patent


Assay Description
Microplates were coated with recombinant human integrin αVβ6 (2 μg/mL) in PBS (100 μL/well 25 C., overnight). The coating soluti...


US Patent US10793564 (2020)

More data for this
Ligand-Target Pair
Integrin alpha-V/alpha-5


(Homo sapiens (Human))
BDBM465330
PNG
(US10793564, Compound 120)
Show SMILES OC(=O)[C@H](CCN(CCCCc1ccc2CCCNc2n1)CC(F)F)Nc1ccncn1
Show InChI InChI=1S/C22H30F2N6O2/c23-19(24)14-30(13-9-18(22(31)32)29-20-8-11-25-15-27-20)12-2-1-5-17-7-6-16-4-3-10-26-21(16)28-17/h6-8,11,15,18-19H,1-5,9-10,12-14H2,(H,26,28)(H,31,32)(H,25,27,29)/t18-/m0/s1
PDB

Reactome pathway

UniProtKB/SwissProt

antibodypedia
antibodypedia
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a>1.00E+3n/an/an/an/an/an/a



PLIANT THERAPEUTICS, INC.

US Patent


Assay Description
Microplates were coated with recombinant human integrin αVβ6 (2 μg/mL) in PBS (100 μL/well 25 C., overnight). The coating soluti...


US Patent US10793564 (2020)

More data for this
Ligand-Target Pair
Integrin alpha-V/alpha-5


(Homo sapiens (Human))
BDBM465314
PNG
(US10793564, Compound 103)
Show SMILES CS(=O)(=O)CCN(CCCCc1ccc2CCCNc2n1)CC[C@H](Nc1ncc(Br)cn1)C(O)=O
Show InChI InChI=1S/C23H33BrN6O4S/c1-35(33,34)14-13-30(12-9-20(22(31)32)29-23-26-15-18(24)16-27-23)11-3-2-6-19-8-7-17-5-4-10-25-21(17)28-19/h7-8,15-16,20H,2-6,9-14H2,1H3,(H,25,28)(H,31,32)(H,26,27,29)/t20-/m0/s1
PDB

Reactome pathway

UniProtKB/SwissProt

antibodypedia
antibodypedia
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a>1.00E+3n/an/an/an/an/an/a



PLIANT THERAPEUTICS, INC.

US Patent


Assay Description
Microplates were coated with recombinant human integrin αVβ6 (2 μg/mL) in PBS (100 μL/well 25 C., overnight). The coating soluti...


US Patent US10793564 (2020)

More data for this
Ligand-Target Pair
Integrin alpha-V/alpha-5


(Homo sapiens (Human))
BDBM465313
PNG
(US10793564, Compound 102)
Show SMILES CS(=O)(=O)CCN(CCCCc1ccc2CCCNc2n1)CC[C@H](Nc1ncc(cn1)C(F)(F)F)C(O)=O
Show InChI InChI=1S/C24H33F3N6O4S/c1-38(36,37)14-13-33(11-3-2-6-19-8-7-17-5-4-10-28-21(17)31-19)12-9-20(22(34)35)32-23-29-15-18(16-30-23)24(25,26)27/h7-8,15-16,20H,2-6,9-14H2,1H3,(H,28,31)(H,34,35)(H,29,30,32)/t20-/m0/s1
PDB

Reactome pathway

UniProtKB/SwissProt

antibodypedia
antibodypedia
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a>1.00E+3n/an/an/an/an/an/a



PLIANT THERAPEUTICS, INC.

US Patent


Assay Description
Microplates were coated with recombinant human integrin αVβ6 (2 μg/mL) in PBS (100 μL/well 25 C., overnight). The coating soluti...


US Patent US10793564 (2020)

More data for this
Ligand-Target Pair
Integrin alpha-V/alpha-5


(Homo sapiens (Human))
BDBM465308
PNG
(US10793564, Compound 97)
Show SMILES OC(=O)[C@H](CCN(CCCCc1ccc2CCCNc2n1)CC(F)F)Nc1ccnc(n1)C(F)(F)F
Show InChI InChI=1S/C23H29F5N6O2/c24-18(25)14-34(12-2-1-5-16-7-6-15-4-3-10-29-20(15)31-16)13-9-17(21(35)36)32-19-8-11-30-22(33-19)23(26,27)28/h6-8,11,17-18H,1-5,9-10,12-14H2,(H,29,31)(H,35,36)(H,30,32,33)/t17-/m0/s1
PDB

Reactome pathway

UniProtKB/SwissProt

antibodypedia
antibodypedia
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a>1.00E+3n/an/an/an/an/an/a



PLIANT THERAPEUTICS, INC.

US Patent


Assay Description
Microplates were coated with recombinant human integrin αVβ6 (2 μg/mL) in PBS (100 μL/well 25 C., overnight). The coating soluti...


US Patent US10793564 (2020)

More data for this
Ligand-Target Pair
Integrin alpha-V/alpha-5


(Homo sapiens (Human))
BDBM465352
PNG
(US10793564, Compound 142)
Show SMILES OC(=O)[C@H](CCN(CCCCc1ccc2CCCNc2n1)CC(F)F)Nc1cc(ncn1)-c1ccccc1
Show InChI InChI=1S/C28H34F2N6O2/c29-25(30)18-36(15-5-4-10-22-12-11-21-9-6-14-31-27(21)34-22)16-13-23(28(37)38)35-26-17-24(32-19-33-26)20-7-2-1-3-8-20/h1-3,7-8,11-12,17,19,23,25H,4-6,9-10,13-16,18H2,(H,31,34)(H,37,38)(H,32,33,35)/t23-/m0/s1
PDB

Reactome pathway

UniProtKB/SwissProt

antibodypedia
antibodypedia
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a>1.00E+3n/an/an/an/an/an/a



PLIANT THERAPEUTICS, INC.

US Patent


Assay Description
Microplates were coated with recombinant human integrin αVβ6 (2 μg/mL) in PBS (100 μL/well 25 C., overnight). The coating soluti...


US Patent US10793564 (2020)

More data for this
Ligand-Target Pair
Integrin alpha-V/alpha-5


(Homo sapiens (Human))
BDBM465306
PNG
(US10793564, Compound 95)
Show SMILES OC(=O)[C@H](CCN(CCCCc1ccc2CCCNc2n1)CC(F)F)Nc1ncc(cn1)C(F)(F)F
Show InChI InChI=1S/C23H29F5N6O2/c24-19(25)14-34(10-2-1-5-17-7-6-15-4-3-9-29-20(15)32-17)11-8-18(21(35)36)33-22-30-12-16(13-31-22)23(26,27)28/h6-7,12-13,18-19H,1-5,8-11,14H2,(H,29,32)(H,35,36)(H,30,31,33)/t18-/m0/s1
PDB

Reactome pathway

UniProtKB/SwissProt

antibodypedia
antibodypedia
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a>1.00E+3n/an/an/an/an/an/a



PLIANT THERAPEUTICS, INC.

US Patent


Assay Description
Microplates were coated with recombinant human integrin αVβ6 (2 μg/mL) in PBS (100 μL/well 25 C., overnight). The coating soluti...


US Patent US10793564 (2020)

More data for this
Ligand-Target Pair
Integrin alpha-V/alpha-5


(Homo sapiens (Human))
BDBM465307
PNG
(US10793564, Compound 96)
Show SMILES OC(=O)[C@H](CCN(CCCCc1ccc2CCCNc2n1)CC(F)F)Nc1ncc(Br)cn1
Show InChI InChI=1S/C22H29BrF2N6O2/c23-16-12-27-22(28-13-16)30-18(21(32)33)8-11-31(14-19(24)25)10-2-1-5-17-7-6-15-4-3-9-26-20(15)29-17/h6-7,12-13,18-19H,1-5,8-11,14H2,(H,26,29)(H,32,33)(H,27,28,30)/t18-/m0/s1
PDB

Reactome pathway

UniProtKB/SwissProt

antibodypedia
antibodypedia
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a>1.00E+3n/an/an/an/an/an/a



PLIANT THERAPEUTICS, INC.

US Patent


Assay Description
Microplates were coated with recombinant human integrin αVβ6 (2 μg/mL) in PBS (100 μL/well 25 C., overnight). The coating soluti...


US Patent US10793564 (2020)

More data for this
Ligand-Target Pair
* indicates data uncertainty>20%