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Found 340 Enz. Inhib. hit(s) with all data for entry = 9425
TargetBile acid receptor(Homo sapiens (Human))
Ardelyx

US Patent
LigandPNGBDBM465384(US10793568, Compound I-3)
Affinity DataEC50:  25.1nMAssay Description:The affinity of FXR ligands for the ligand binding domain of FXR was determined using a commercially available human FXR ligand binding assay (Lantha...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBile acid receptor(Homo sapiens (Human))
Ardelyx

US Patent
LigandPNGBDBM465382(US10793568, Compound I-1)
Affinity DataEC50:  39.8nMAssay Description:The affinity of FXR ligands for the ligand binding domain of FXR was determined using a commercially available human FXR ligand binding assay (Lantha...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBile acid receptor(Homo sapiens (Human))
Ardelyx

US Patent
LigandPNGBDBM465383(US10793568, Compound I-2)
Affinity DataEC50:  50.1nMAssay Description:The affinity of FXR ligands for the ligand binding domain of FXR was determined using a commercially available human FXR ligand binding assay (Lantha...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBile acid receptor(Homo sapiens (Human))
Ardelyx

US Patent
LigandPNGBDBM465385(US10793568, Compound I-4)
Affinity DataEC50:  50.1nMAssay Description:The affinity of FXR ligands for the ligand binding domain of FXR was determined using a commercially available human FXR ligand binding assay (Lantha...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBile acid receptor(Homo sapiens (Human))
Ardelyx

US Patent
LigandPNGBDBM465386(US10793568, Compound I-5)
Affinity DataEC50:  63.1nMAssay Description:The affinity of FXR ligands for the ligand binding domain of FXR was determined using a commercially available human FXR ligand binding assay (Lantha...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBile acid receptor(Homo sapiens (Human))
Ardelyx

US Patent
LigandPNGBDBM465387(US10793568, Compound I-6)
Affinity DataEC50:  20nMAssay Description:The affinity of FXR ligands for the ligand binding domain of FXR was determined using a commercially available human FXR ligand binding assay (Lantha...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBile acid receptor(Homo sapiens (Human))
Ardelyx

US Patent
LigandPNGBDBM465388(US10793568, Compound I-7)
Affinity DataEC50:  39.8nMAssay Description:The affinity of FXR ligands for the ligand binding domain of FXR was determined using a commercially available human FXR ligand binding assay (Lantha...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBile acid receptor(Homo sapiens (Human))
Ardelyx

US Patent
LigandPNGBDBM465389(US10793568, Compound I-8)
Affinity DataEC50:  25.1nMAssay Description:The affinity of FXR ligands for the ligand binding domain of FXR was determined using a commercially available human FXR ligand binding assay (Lantha...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBile acid receptor(Homo sapiens (Human))
Ardelyx

US Patent
LigandPNGBDBM465390(US10793568, Compound I-9)
Affinity DataEC50:  79.4nMAssay Description:The affinity of FXR ligands for the ligand binding domain of FXR was determined using a commercially available human FXR ligand binding assay (Lantha...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBile acid receptor(Homo sapiens (Human))
Ardelyx

US Patent
LigandPNGBDBM465391(US10793568, Compound I-10)
Affinity DataEC50:  100nMAssay Description:The affinity of FXR ligands for the ligand binding domain of FXR was determined using a commercially available human FXR ligand binding assay (Lantha...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBile acid receptor(Homo sapiens (Human))
Ardelyx

US Patent
LigandPNGBDBM465392(US10793568, Compound I-11)
Affinity DataEC50:  20nMAssay Description:The affinity of FXR ligands for the ligand binding domain of FXR was determined using a commercially available human FXR ligand binding assay (Lantha...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBile acid receptor(Homo sapiens (Human))
Ardelyx

US Patent
LigandPNGBDBM465393(US10793568, Compound I-12)
Affinity DataEC50:  1nMAssay Description:The affinity of FXR ligands for the ligand binding domain of FXR was determined using a commercially available human FXR ligand binding assay (Lantha...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBile acid receptor(Homo sapiens (Human))
Ardelyx

US Patent
LigandPNGBDBM465394(US10793568, Compound I-13)
Affinity DataEC50:  2.51nMAssay Description:The affinity of FXR ligands for the ligand binding domain of FXR was determined using a commercially available human FXR ligand binding assay (Lantha...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBile acid receptor(Homo sapiens (Human))
Ardelyx

US Patent
LigandPNGBDBM465395(US10793568, Compound I-14)
Affinity DataEC50:  2.51nMAssay Description:The affinity of FXR ligands for the ligand binding domain of FXR was determined using a commercially available human FXR ligand binding assay (Lantha...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBile acid receptor(Homo sapiens (Human))
Ardelyx

US Patent
LigandPNGBDBM465396(US10793568, Compound I-15)
Affinity DataEC50:  15.8nMAssay Description:The affinity of FXR ligands for the ligand binding domain of FXR was determined using a commercially available human FXR ligand binding assay (Lantha...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBile acid receptor(Homo sapiens (Human))
Ardelyx

US Patent
LigandPNGBDBM465397(US10793568, Compound I-16)
Affinity DataEC50:  1.58nMAssay Description:The affinity of FXR ligands for the ligand binding domain of FXR was determined using a commercially available human FXR ligand binding assay (Lantha...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBile acid receptor(Homo sapiens (Human))
Ardelyx

US Patent
LigandPNGBDBM465398(US10793568, Compound I-17)
Affinity DataEC50:  6.31nMAssay Description:The affinity of FXR ligands for the ligand binding domain of FXR was determined using a commercially available human FXR ligand binding assay (Lantha...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBile acid receptor(Homo sapiens (Human))
Ardelyx

US Patent
LigandPNGBDBM465399(US10793568, Compound I-18)
Affinity DataEC50:  1.58nMAssay Description:The affinity of FXR ligands for the ligand binding domain of FXR was determined using a commercially available human FXR ligand binding assay (Lantha...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBile acid receptor(Homo sapiens (Human))
Ardelyx

US Patent
LigandPNGBDBM465400(US10793568, Compound I-19)
Affinity DataEC50:  10nMAssay Description:The affinity of FXR ligands for the ligand binding domain of FXR was determined using a commercially available human FXR ligand binding assay (Lantha...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBile acid receptor(Homo sapiens (Human))
Ardelyx

US Patent
LigandPNGBDBM465401(US10793568, Compound I-20)
Affinity DataEC50:  3.98nMAssay Description:The affinity of FXR ligands for the ligand binding domain of FXR was determined using a commercially available human FXR ligand binding assay (Lantha...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBile acid receptor(Homo sapiens (Human))
Ardelyx

US Patent
LigandPNGBDBM465402(US10793568, Compound I-21)
Affinity DataEC50:  100nMAssay Description:The affinity of FXR ligands for the ligand binding domain of FXR was determined using a commercially available human FXR ligand binding assay (Lantha...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBile acid receptor(Homo sapiens (Human))
Ardelyx

US Patent
LigandPNGBDBM465403(US10793568, Compound I-22)
Affinity DataEC50:  316nMAssay Description:The affinity of FXR ligands for the ligand binding domain of FXR was determined using a commercially available human FXR ligand binding assay (Lantha...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBile acid receptor(Homo sapiens (Human))
Ardelyx

US Patent
LigandPNGBDBM465404(US10793568, Compound I-23)
Affinity DataEC50:  3.16E+3nMAssay Description:The affinity of FXR ligands for the ligand binding domain of FXR was determined using a commercially available human FXR ligand binding assay (Lantha...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBile acid receptor(Homo sapiens (Human))
Ardelyx

US Patent
LigandPNGBDBM465405(US10793568, Compound I-24)
Affinity DataEC50:  12.6nMAssay Description:The affinity of FXR ligands for the ligand binding domain of FXR was determined using a commercially available human FXR ligand binding assay (Lantha...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBile acid receptor(Homo sapiens (Human))
Ardelyx

US Patent
LigandPNGBDBM465406(US10793568, Compound I-25)
Affinity DataEC50:  3.98nMAssay Description:The affinity of FXR ligands for the ligand binding domain of FXR was determined using a commercially available human FXR ligand binding assay (Lantha...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBile acid receptor(Homo sapiens (Human))
Ardelyx

US Patent
LigandPNGBDBM465407(US10793568, Compound I-26)
Affinity DataEC50:  3.98nMAssay Description:The affinity of FXR ligands for the ligand binding domain of FXR was determined using a commercially available human FXR ligand binding assay (Lantha...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBile acid receptor(Homo sapiens (Human))
Ardelyx

US Patent
LigandPNGBDBM465408(US10793568, Compound I-27)
Affinity DataEC50:  12.6nMAssay Description:The affinity of FXR ligands for the ligand binding domain of FXR was determined using a commercially available human FXR ligand binding assay (Lantha...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBile acid receptor(Homo sapiens (Human))
Ardelyx

US Patent
LigandPNGBDBM465409(US10793568, Compound I-28)
Affinity DataEC50:  1.26nMAssay Description:The affinity of FXR ligands for the ligand binding domain of FXR was determined using a commercially available human FXR ligand binding assay (Lantha...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBile acid receptor(Homo sapiens (Human))
Ardelyx

US Patent
LigandPNGBDBM465410(US10793568, Compound I-29)
Affinity DataEC50:  15.8nMAssay Description:The affinity of FXR ligands for the ligand binding domain of FXR was determined using a commercially available human FXR ligand binding assay (Lantha...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBile acid receptor(Homo sapiens (Human))
Ardelyx

US Patent
LigandPNGBDBM465411(US10793568, Compound I-30)
Affinity DataEC50:  2.51nMAssay Description:The affinity of FXR ligands for the ligand binding domain of FXR was determined using a commercially available human FXR ligand binding assay (Lantha...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBile acid receptor(Homo sapiens (Human))
Ardelyx

US Patent
LigandPNGBDBM465412(US10793568, Compound I-31)
Affinity DataEC50:  39.8nMAssay Description:The affinity of FXR ligands for the ligand binding domain of FXR was determined using a commercially available human FXR ligand binding assay (Lantha...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBile acid receptor(Homo sapiens (Human))
Ardelyx

US Patent
LigandPNGBDBM465413(US10793568, Compound I-32)
Affinity DataEC50:  25.1nMAssay Description:The affinity of FXR ligands for the ligand binding domain of FXR was determined using a commercially available human FXR ligand binding assay (Lantha...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBile acid receptor(Homo sapiens (Human))
Ardelyx

US Patent
LigandPNGBDBM465414(US10793568, Compound I-33)
Affinity DataEC50:  25.1nMAssay Description:The affinity of FXR ligands for the ligand binding domain of FXR was determined using a commercially available human FXR ligand binding assay (Lantha...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBile acid receptor(Homo sapiens (Human))
Ardelyx

US Patent
LigandPNGBDBM465415(US10793568, Compound I-34)
Affinity DataEC50: >3.16E+4nMAssay Description:The affinity of FXR ligands for the ligand binding domain of FXR was determined using a commercially available human FXR ligand binding assay (Lantha...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBile acid receptor(Homo sapiens (Human))
Ardelyx

US Patent
LigandPNGBDBM465416(US10793568, Compound I-35)
Affinity DataEC50: >3.16E+4nMAssay Description:The affinity of FXR ligands for the ligand binding domain of FXR was determined using a commercially available human FXR ligand binding assay (Lantha...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBile acid receptor(Homo sapiens (Human))
Ardelyx

US Patent
LigandPNGBDBM465417(US10793568, Compound I-36)
Affinity DataEC50:  3.98E+3nMAssay Description:The affinity of FXR ligands for the ligand binding domain of FXR was determined using a commercially available human FXR ligand binding assay (Lantha...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBile acid receptor(Homo sapiens (Human))
Ardelyx

US Patent
LigandPNGBDBM465418(US10793568, Compound I-37)
Affinity DataEC50: >3.16E+4nMAssay Description:The affinity of FXR ligands for the ligand binding domain of FXR was determined using a commercially available human FXR ligand binding assay (Lantha...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBile acid receptor(Homo sapiens (Human))
Ardelyx

US Patent
LigandPNGBDBM465419(US10793568, Compound I-38)
Affinity DataEC50:  501nMAssay Description:The affinity of FXR ligands for the ligand binding domain of FXR was determined using a commercially available human FXR ligand binding assay (Lantha...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBile acid receptor(Homo sapiens (Human))
Ardelyx

US Patent
LigandPNGBDBM465420(US10793568, Compound I-39)
Affinity DataEC50:  15.8nMAssay Description:The affinity of FXR ligands for the ligand binding domain of FXR was determined using a commercially available human FXR ligand binding assay (Lantha...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBile acid receptor(Homo sapiens (Human))
Ardelyx

US Patent
LigandPNGBDBM465421(US10793568, Compound I-40)
Affinity DataEC50: >3.16E+4nMAssay Description:The affinity of FXR ligands for the ligand binding domain of FXR was determined using a commercially available human FXR ligand binding assay (Lantha...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBile acid receptor(Homo sapiens (Human))
Ardelyx

US Patent
LigandPNGBDBM465422(US10793568, Compound I-41)
Affinity DataEC50: >3.16E+4nMAssay Description:The affinity of FXR ligands for the ligand binding domain of FXR was determined using a commercially available human FXR ligand binding assay (Lantha...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBile acid receptor(Homo sapiens (Human))
Ardelyx

US Patent
LigandPNGBDBM465423(US10793568, Compound I-42)
Affinity DataEC50:  25.1nMAssay Description:The affinity of FXR ligands for the ligand binding domain of FXR was determined using a commercially available human FXR ligand binding assay (Lantha...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBile acid receptor(Homo sapiens (Human))
Ardelyx

US Patent
LigandPNGBDBM465424(US10793568, Compound I-43)
Affinity DataEC50:  15.8nMAssay Description:The affinity of FXR ligands for the ligand binding domain of FXR was determined using a commercially available human FXR ligand binding assay (Lantha...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBile acid receptor(Homo sapiens (Human))
Ardelyx

US Patent
LigandPNGBDBM465425(US10793568, Compound I-44)
Affinity DataEC50:  25.1nMAssay Description:The affinity of FXR ligands for the ligand binding domain of FXR was determined using a commercially available human FXR ligand binding assay (Lantha...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBile acid receptor(Homo sapiens (Human))
Ardelyx

US Patent
LigandPNGBDBM465426(US10793568, Compound I-45)
Affinity DataEC50:  31.6nMAssay Description:The affinity of FXR ligands for the ligand binding domain of FXR was determined using a commercially available human FXR ligand binding assay (Lantha...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBile acid receptor(Homo sapiens (Human))
Ardelyx

US Patent
LigandPNGBDBM465427(US10793568, Compound I-46)
Affinity DataEC50:  12.6nMAssay Description:The affinity of FXR ligands for the ligand binding domain of FXR was determined using a commercially available human FXR ligand binding assay (Lantha...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBile acid receptor(Homo sapiens (Human))
Ardelyx

US Patent
LigandPNGBDBM465428(US10793568, Compound I-47)
Affinity DataEC50:  15.8nMAssay Description:The affinity of FXR ligands for the ligand binding domain of FXR was determined using a commercially available human FXR ligand binding assay (Lantha...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBile acid receptor(Homo sapiens (Human))
Ardelyx

US Patent
LigandPNGBDBM465429(US10793568, Compound I-48)
Affinity DataEC50:  25.1nMAssay Description:The affinity of FXR ligands for the ligand binding domain of FXR was determined using a commercially available human FXR ligand binding assay (Lantha...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBile acid receptor(Homo sapiens (Human))
Ardelyx

US Patent
LigandPNGBDBM465430(US10793568, Compound I-49)
Affinity DataEC50:  10nMAssay Description:The affinity of FXR ligands for the ligand binding domain of FXR was determined using a commercially available human FXR ligand binding assay (Lantha...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBile acid receptor(Homo sapiens (Human))
Ardelyx

US Patent
LigandPNGBDBM465431(US10793568, Compound I-50)
Affinity DataEC50:  158nMAssay Description:The affinity of FXR ligands for the ligand binding domain of FXR was determined using a commercially available human FXR ligand binding assay (Lantha...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
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