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Found 7 Enz. Inhib. hit(s) with all data for entry = 9441
Target4-aminobutyrate aminotransferase, mitochondrial(Homo sapiens (Human))
Northwestern University

US Patent
LigandPNGBDBM466532(US10800753, Compound 17)
Affinity DataKi:  1.82E+5nMAssay Description:Inhibition constants were determined by monitoring GABA-AT activity in the presence of 0-50 mM concentrations of synthesized analogues using a couple...More data for this Ligand-Target Pair
In DepthDetails US Patent
Target4-aminobutyrate aminotransferase, mitochondrial(Homo sapiens (Human))
Northwestern University

US Patent
LigandPNGBDBM323800((2R,4S)-4-Aminotetrahydrothiophene-2-carboxylic ac...)
Affinity DataKi:  2.23E+6nMAssay Description:Inhibition constants were determined by monitoring GABA-AT activity in the presence of 0-50 mM concentrations of synthesized analogues using a couple...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target4-aminobutyrate aminotransferase, mitochondrial(Homo sapiens (Human))
Northwestern University

US Patent
LigandPNGBDBM466536(US10800753, Compound 19)
Affinity DataKi:  3.20E+6nMAssay Description:Inhibition constants were determined by monitoring GABA-AT activity in the presence of 0-50 mM concentrations of synthesized analogues using a couple...More data for this Ligand-Target Pair
In DepthDetails US Patent
Target4-aminobutyrate aminotransferase, mitochondrial(Homo sapiens (Human))
Northwestern University

US Patent
LigandPNGBDBM50357219(CHEMBL1361446 | US10800753, Compound (S)-vigabatri...)
Affinity DataKi:  3.20E+6nMAssay Description:Inhibition constants were determined by monitoring GABA-AT activity in the presence of 0-50 mM concentrations of synthesized analogues using a couple...More data for this Ligand-Target Pair
In DepthDetails US Patent
Target4-aminobutyrate aminotransferase, mitochondrial(Homo sapiens (Human))
Northwestern University

US Patent
LigandPNGBDBM466538(US10800753, Compound 21)
Affinity DataKi:  3.30E+6nMAssay Description:Inhibition constants were determined by monitoring GABA-AT activity in the presence of 0-50 mM concentrations of synthesized analogues using a couple...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target4-aminobutyrate aminotransferase, mitochondrial(Homo sapiens (Human))
Northwestern University

US Patent
LigandPNGBDBM466537(US10800753, Compound 20)
Affinity DataKi:  3.40E+6nMAssay Description:Inhibition constants were determined by monitoring GABA-AT activity in the presence of 0-50 mM concentrations of synthesized analogues using a couple...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target4-aminobutyrate aminotransferase, mitochondrial(Homo sapiens (Human))
Northwestern University

US Patent
LigandPNGBDBM466539(US10800753, Compound 22)
Affinity DataKi:  7.50E+6nMAssay Description:Inhibition constants were determined by monitoring GABA-AT activity in the presence of 0-50 mM concentrations of synthesized analogues using a couple...More data for this Ligand-Target Pair
In DepthDetails US Patent