BindingDB logo
myBDB logout

Patent code US10800755

Compile Data Set for Download or QSAR

Found 217 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
5-hydroxytryptamine receptor 1A


(Homo sapiens (Human))
BDBM466559
PNG
(US10800755, Example 14)
Show SMILES Cc1cccc(n1)C1=CCN(CCNC(=O)C2CCC(F)(F)CC2)CC1
Show InChI InChI=1S/C20H27F2N3O/c1-15-3-2-4-18(24-15)16-7-12-25(13-8-16)14-11-23-19(26)17-5-9-20(21,22)10-6-17/h2-4,7,17H,5-6,8-14H2,1H3,(H,23,26)
PDB

Reactome pathway

UniProtKB/SwissProt
UniProtKB/TrEMBL

antibodypedia
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 0.100n/an/an/an/an/an/a



SUMITOMO DAINIPPON PHARMA CO., LTD.

US Patent


Assay Description
The binding affinity of the present compounds to human 5-HT1A receptor, human D4 receptor, and human D2 receptor was measured in a manner mentioned b...


US Patent US10800755 (2020)

More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Homo sapiens (Human))
BDBM466556
PNG
(4,4-Difluoro-N-{2-[6-(trifluoromethyl)-3′,6&...)
Show SMILES FC(F)(F)c1cccc(n1)C1=CCN(CCNC(=O)C2CCC(F)(F)CC2)CC1
Show InChI InChI=1S/C20H24F5N3O/c21-19(22)8-4-15(5-9-19)18(29)26-10-13-28-11-6-14(7-12-28)16-2-1-3-17(27-16)20(23,24)25/h1-3,6,15H,4-5,7-13H2,(H,26,29)
PDB

Reactome pathway

UniProtKB/SwissProt
UniProtKB/TrEMBL

antibodypedia
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 0.200n/an/an/an/an/an/a



SUMITOMO DAINIPPON PHARMA CO., LTD.

US Patent


Assay Description
The binding affinity of the present compounds to human 5-HT1A receptor, human D4 receptor, and human D2 receptor was measured in a manner mentioned b...


US Patent US10800755 (2020)

More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Homo sapiens (Human))
BDBM466577
PNG
(2,2-Dimethyl-N-{2-[6-(trifluoromethyl)-3′,6&...)
Show SMILES CC(C)(C)C(=O)NCCN1CCC(=CC1)c1cccc(n1)C(F)(F)F
Show InChI InChI=1S/C18H24F3N3O/c1-17(2,3)16(25)22-9-12-24-10-7-13(8-11-24)14-5-4-6-15(23-14)18(19,20)21/h4-7H,8-12H2,1-3H3,(H,22,25)
PDB

Reactome pathway

UniProtKB/SwissProt
UniProtKB/TrEMBL

antibodypedia
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 0.300n/an/an/an/an/an/a



SUMITOMO DAINIPPON PHARMA CO., LTD.

US Patent


Assay Description
The binding affinity of the present compounds to human 5-HT1A receptor, human D4 receptor, and human D2 receptor was measured in a manner mentioned b...


US Patent US10800755 (2020)

More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Homo sapiens (Human))
BDBM466535
PNG
(4,4-Difluoro-N-(2-{4-[6-(trifluoromethyl)pyridin-2...)
Show SMILES FC(F)(F)c1cccc(n1)C1CCN(CCNC(=O)C2CCC(F)(F)CC2)CC1
Show InChI InChI=1S/C20H26F5N3O/c21-19(22)8-4-15(5-9-19)18(29)26-10-13-28-11-6-14(7-12-28)16-2-1-3-17(27-16)20(23,24)25/h1-3,14-15H,4-13H2,(H,26,29)
PDB

Reactome pathway

UniProtKB/SwissProt
UniProtKB/TrEMBL

antibodypedia
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 0.400n/an/an/an/an/an/a



SUMITOMO DAINIPPON PHARMA CO., LTD.

US Patent


Assay Description
The binding affinity of the present compounds to human 5-HT1A receptor, human D4 receptor, and human D2 receptor was measured in a manner mentioned b...


US Patent US10800755 (2020)

More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Homo sapiens (Human))
BDBM466547
PNG
(US10800755, Example 4)
Show SMILES Cc1cccc(n1)C1CCN(CCNC(=O)C2CCC(F)(F)CC2)CC1
Show InChI InChI=1S/C20H29F2N3O/c1-15-3-2-4-18(24-15)16-7-12-25(13-8-16)14-11-23-19(26)17-5-9-20(21,22)10-6-17/h2-4,16-17H,5-14H2,1H3,(H,23,26)
PDB

Reactome pathway

UniProtKB/SwissProt
UniProtKB/TrEMBL

antibodypedia
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 0.400n/an/an/an/an/an/a



SUMITOMO DAINIPPON PHARMA CO., LTD.

US Patent


Assay Description
The binding affinity of the present compounds to human 5-HT1A receptor, human D4 receptor, and human D2 receptor was measured in a manner mentioned b...


US Patent US10800755 (2020)

More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Homo sapiens (Human))
BDBM466575
PNG
(N-[2-(6-Methyl-3′,6′-dihydro[2,4′...)
Show SMILES Cc1cccc(n1)C1=CCN(CCNC(=O)C2CCOCC2)CC1
Show InChI InChI=1S/C19H27N3O2/c1-15-3-2-4-18(21-15)16-5-10-22(11-6-16)12-9-20-19(23)17-7-13-24-14-8-17/h2-5,17H,6-14H2,1H3,(H,20,23)
PDB

Reactome pathway

UniProtKB/SwissProt
UniProtKB/TrEMBL

antibodypedia
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 0.400n/an/an/an/an/an/a



SUMITOMO DAINIPPON PHARMA CO., LTD.

US Patent


Assay Description
The binding affinity of the present compounds to human 5-HT1A receptor, human D4 receptor, and human D2 receptor was measured in a manner mentioned b...


US Patent US10800755 (2020)

More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Homo sapiens (Human))
BDBM466565
PNG
(US10800755, Example 19)
Show SMILES FC(F)(F)c1cccc(n1)C1=CCN(CCNC(=O)C2CCOCC2)CC1
Show InChI InChI=1S/C19H24F3N3O2/c20-19(21,22)17-3-1-2-16(24-17)14-4-9-25(10-5-14)11-8-23-18(26)15-6-12-27-13-7-15/h1-4,15H,5-13H2,(H,23,26)
PDB

Reactome pathway

UniProtKB/SwissProt
UniProtKB/TrEMBL

antibodypedia
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 0.800n/an/an/an/an/an/a



SUMITOMO DAINIPPON PHARMA CO., LTD.

US Patent


Assay Description
The binding affinity of the present compounds to human 5-HT1A receptor, human D4 receptor, and human D2 receptor was measured in a manner mentioned b...


US Patent US10800755 (2020)

More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Homo sapiens (Human))
BDBM466553
PNG
(US10800755, Example 9)
Show SMILES CC(C)(C)C(=O)NCCN1CCC(CC1)c1cccc(n1)C(F)(F)F
Show InChI InChI=1S/C18H26F3N3O/c1-17(2,3)16(25)22-9-12-24-10-7-13(8-11-24)14-5-4-6-15(23-14)18(19,20)21/h4-6,13H,7-12H2,1-3H3,(H,22,25)
PDB

Reactome pathway

UniProtKB/SwissProt
UniProtKB/TrEMBL

antibodypedia
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 1.10n/an/an/an/an/an/a



SUMITOMO DAINIPPON PHARMA CO., LTD.

US Patent


Assay Description
The binding affinity of the present compounds to human 5-HT1A receptor, human D4 receptor, and human D2 receptor was measured in a manner mentioned b...


US Patent US10800755 (2020)

More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Homo sapiens (Human))
BDBM466557
PNG
(US10800755, Example 13)
Show SMILES Cc1cccc(n1)C1=CCN(CCNC(=O)[C@H]2C[C@@H]3CC[C@H]2O3)CC1
Show InChI InChI=1S/C20H27N3O2/c1-14-3-2-4-18(22-14)15-7-10-23(11-8-15)12-9-21-20(24)17-13-16-5-6-19(17)25-16/h2-4,7,16-17,19H,5-6,8-13H2,1H3,(H,21,24)/t16-,17-,19+/m0/s1
PDB

Reactome pathway

UniProtKB/SwissProt
UniProtKB/TrEMBL

antibodypedia
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 1.10n/an/an/an/an/an/a



SUMITOMO DAINIPPON PHARMA CO., LTD.

US Patent


Assay Description
The binding affinity of the present compounds to human 5-HT1A receptor, human D4 receptor, and human D2 receptor was measured in a manner mentioned b...


US Patent US10800755 (2020)

More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Homo sapiens (Human))
BDBM466552
PNG
(N-{2-[4-(6-Methylpyridin-2-yl)piperidin-1-yl]ethyl...)
Show SMILES Cc1cccc(n1)C1CCN(CCNC(=O)C2CCOCC2)CC1
Show InChI InChI=1S/C19H29N3O2/c1-15-3-2-4-18(21-15)16-5-10-22(11-6-16)12-9-20-19(23)17-7-13-24-14-8-17/h2-4,16-17H,5-14H2,1H3,(H,20,23)
PDB

Reactome pathway

UniProtKB/SwissProt
UniProtKB/TrEMBL

antibodypedia
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 1.40n/an/an/an/an/an/a



SUMITOMO DAINIPPON PHARMA CO., LTD.

US Patent


Assay Description
The binding affinity of the present compounds to human 5-HT1A receptor, human D4 receptor, and human D2 receptor was measured in a manner mentioned b...


US Patent US10800755 (2020)

More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Homo sapiens (Human))
BDBM466554
PNG
(US10800755, Example 10)
Show SMILES Cc1cccc(n1)C1CCN(CCNC(=O)C(C)(C)C)CC1
Show InChI InChI=1S/C18H29N3O/c1-14-6-5-7-16(20-14)15-8-11-21(12-9-15)13-10-19-17(22)18(2,3)4/h5-7,15H,8-13H2,1-4H3,(H,19,22)
PDB

Reactome pathway

UniProtKB/SwissProt
UniProtKB/TrEMBL

antibodypedia
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 1.40n/an/an/an/an/an/a



SUMITOMO DAINIPPON PHARMA CO., LTD.

US Patent


Assay Description
The binding affinity of the present compounds to human 5-HT1A receptor, human D4 receptor, and human D2 receptor was measured in a manner mentioned b...


US Patent US10800755 (2020)

More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Homo sapiens (Human))
BDBM466576
PNG
(2,2-Dimethyl-N-[2-(6-methyl-3′,6′-dihy...)
Show SMILES Cc1cccc(n1)C1=CCN(CCNC(=O)C(C)(C)C)CC1
Show InChI InChI=1S/C18H27N3O/c1-14-6-5-7-16(20-14)15-8-11-21(12-9-15)13-10-19-17(22)18(2,3)4/h5-8H,9-13H2,1-4H3,(H,19,22)
PDB

Reactome pathway

UniProtKB/SwissProt
UniProtKB/TrEMBL

antibodypedia
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 1.40n/an/an/an/an/an/a



SUMITOMO DAINIPPON PHARMA CO., LTD.

US Patent


Assay Description
The binding affinity of the present compounds to human 5-HT1A receptor, human D4 receptor, and human D2 receptor was measured in a manner mentioned b...


US Patent US10800755 (2020)

More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Homo sapiens (Human))
BDBM466555
PNG
(US10800755, Example 11)
Show SMILES FC(F)(F)c1cccc(n1)C1CCN(CCNC(=O)C2CCOCC2)CC1
Show InChI InChI=1S/C19H26F3N3O2/c20-19(21,22)17-3-1-2-16(24-17)14-4-9-25(10-5-14)11-8-23-18(26)15-6-12-27-13-7-15/h1-3,14-15H,4-13H2,(H,23,26)
PDB

Reactome pathway

UniProtKB/SwissProt
UniProtKB/TrEMBL

antibodypedia
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 2.10n/an/an/an/an/an/a



SUMITOMO DAINIPPON PHARMA CO., LTD.

US Patent


Assay Description
The binding affinity of the present compounds to human 5-HT1A receptor, human D4 receptor, and human D2 receptor was measured in a manner mentioned b...


US Patent US10800755 (2020)

More data for this
Ligand-Target Pair
D(4) dopamine receptor


(Homo sapiens)
BDBM466577
PNG
(2,2-Dimethyl-N-{2-[6-(trifluoromethyl)-3′,6&...)
Show SMILES CC(C)(C)C(=O)NCCN1CCC(=CC1)c1cccc(n1)C(F)(F)F
Show InChI InChI=1S/C18H24F3N3O/c1-17(2,3)16(25)22-9-12-24-10-7-13(8-11-24)14-5-4-6-15(23-14)18(19,20)21/h4-7H,8-12H2,1-3H3,(H,22,25)
Reactome pathway

UniProtKB/TrEMBL

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 2.90n/an/an/an/an/an/a



SUMITOMO DAINIPPON PHARMA CO., LTD.

US Patent


Assay Description
The binding affinity of the present compounds to human 5-HT1A receptor, human D4 receptor, and human D2 receptor was measured in a manner mentioned b...


US Patent US10800755 (2020)

More data for this
Ligand-Target Pair
D(4) dopamine receptor


(Homo sapiens)
BDBM466559
PNG
(US10800755, Example 14)
Show SMILES Cc1cccc(n1)C1=CCN(CCNC(=O)C2CCC(F)(F)CC2)CC1
Show InChI InChI=1S/C20H27F2N3O/c1-15-3-2-4-18(24-15)16-7-12-25(13-8-16)14-11-23-19(26)17-5-9-20(21,22)10-6-17/h2-4,7,17H,5-6,8-14H2,1H3,(H,23,26)
Reactome pathway

UniProtKB/TrEMBL

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 3n/an/an/an/an/an/a



SUMITOMO DAINIPPON PHARMA CO., LTD.

US Patent


Assay Description
The binding affinity of the present compounds to human 5-HT1A receptor, human D4 receptor, and human D2 receptor was measured in a manner mentioned b...


US Patent US10800755 (2020)

More data for this
Ligand-Target Pair
D(4) dopamine receptor


(Homo sapiens)
BDBM466556
PNG
(4,4-Difluoro-N-{2-[6-(trifluoromethyl)-3′,6&...)
Show SMILES FC(F)(F)c1cccc(n1)C1=CCN(CCNC(=O)C2CCC(F)(F)CC2)CC1
Show InChI InChI=1S/C20H24F5N3O/c21-19(22)8-4-15(5-9-19)18(29)26-10-13-28-11-6-14(7-12-28)16-2-1-3-17(27-16)20(23,24)25/h1-3,6,15H,4-5,7-13H2,(H,26,29)
Reactome pathway

UniProtKB/TrEMBL

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 4.5n/an/an/an/an/an/a



SUMITOMO DAINIPPON PHARMA CO., LTD.

US Patent


Assay Description
The binding affinity of the present compounds to human 5-HT1A receptor, human D4 receptor, and human D2 receptor was measured in a manner mentioned b...


US Patent US10800755 (2020)

More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Homo sapiens (Human))
BDBM466561
PNG
(N-{2-[6-(Trifluoromethyl)-3′,6′-dihydr...)
Show SMILES FC(F)(F)c1cccc(n1)C1=CCN(CCNC(=O)C2CCCOC2)CC1
Show InChI InChI=1S/C19H24F3N3O2/c20-19(21,22)17-5-1-4-16(24-17)14-6-9-25(10-7-14)11-8-23-18(26)15-3-2-12-27-13-15/h1,4-6,15H,2-3,7-13H2,(H,23,26)
PDB

Reactome pathway

UniProtKB/SwissProt
UniProtKB/TrEMBL

antibodypedia
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 6n/an/an/an/an/an/a



SUMITOMO DAINIPPON PHARMA CO., LTD.

US Patent


Assay Description
The binding affinity of the present compounds to human 5-HT1A receptor, human D4 receptor, and human D2 receptor was measured in a manner mentioned b...


US Patent US10800755 (2020)

More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Homo sapiens (Human))
BDBM466566
PNG
(US10800755, Example 20)
Show SMILES Cc1cccc(n1)C1=CCN(CCNC(=O)C2CCCCO2)CC1
Show InChI InChI=1S/C19H27N3O2/c1-15-5-4-6-17(21-15)16-8-11-22(12-9-16)13-10-20-19(23)18-7-2-3-14-24-18/h4-6,8,18H,2-3,7,9-14H2,1H3,(H,20,23)
PDB

Reactome pathway

UniProtKB/SwissProt
UniProtKB/TrEMBL

antibodypedia
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 6.80n/an/an/an/an/an/a



SUMITOMO DAINIPPON PHARMA CO., LTD.

US Patent


Assay Description
The binding affinity of the present compounds to human 5-HT1A receptor, human D4 receptor, and human D2 receptor was measured in a manner mentioned b...


US Patent US10800755 (2020)

More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Homo sapiens (Human))
BDBM466545
PNG
(US10800755, Example 3)
Show SMILES Cc1cccc(n1)C1CCN(CCNC(=O)C2CC3CCC2O3)CC1
Show InChI InChI=1S/C20H29N3O2/c1-14-3-2-4-18(22-14)15-7-10-23(11-8-15)12-9-21-20(24)17-13-16-5-6-19(17)25-16/h2-4,15-17,19H,5-13H2,1H3,(H,21,24)
PDB

Reactome pathway

UniProtKB/SwissProt
UniProtKB/TrEMBL

antibodypedia
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 7.10n/an/an/an/an/an/a



SUMITOMO DAINIPPON PHARMA CO., LTD.

US Patent


Assay Description
The binding affinity of the present compounds to human 5-HT1A receptor, human D4 receptor, and human D2 receptor was measured in a manner mentioned b...


US Patent US10800755 (2020)

More data for this
Ligand-Target Pair
D(4) dopamine receptor


(Homo sapiens)
BDBM466565
PNG
(US10800755, Example 19)
Show SMILES FC(F)(F)c1cccc(n1)C1=CCN(CCNC(=O)C2CCOCC2)CC1
Show InChI InChI=1S/C19H24F3N3O2/c20-19(21,22)17-3-1-2-16(24-17)14-4-9-25(10-5-14)11-8-23-18(26)15-6-12-27-13-7-15/h1-4,15H,5-13H2,(H,23,26)
Reactome pathway

UniProtKB/TrEMBL

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 8n/an/an/an/an/an/a



SUMITOMO DAINIPPON PHARMA CO., LTD.

US Patent


Assay Description
The binding affinity of the present compounds to human 5-HT1A receptor, human D4 receptor, and human D2 receptor was measured in a manner mentioned b...


US Patent US10800755 (2020)

More data for this
Ligand-Target Pair
D(4) dopamine receptor


(Homo sapiens)
BDBM466553
PNG
(US10800755, Example 9)
Show SMILES CC(C)(C)C(=O)NCCN1CCC(CC1)c1cccc(n1)C(F)(F)F
Show InChI InChI=1S/C18H26F3N3O/c1-17(2,3)16(25)22-9-12-24-10-7-13(8-11-24)14-5-4-6-15(23-14)18(19,20)21/h4-6,13H,7-12H2,1-3H3,(H,22,25)
Reactome pathway

UniProtKB/TrEMBL

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 8n/an/an/an/an/an/a



SUMITOMO DAINIPPON PHARMA CO., LTD.

US Patent


Assay Description
The binding affinity of the present compounds to human 5-HT1A receptor, human D4 receptor, and human D2 receptor was measured in a manner mentioned b...


US Patent US10800755 (2020)

More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Homo sapiens (Human))
BDBM466580
PNG
(US10800755, Example 34)
Show SMILES FC(F)c1cccc(n1)C1CCN(CCNC(=O)C2CCOCC2)CC1
Show InChI InChI=1S/C19H27F2N3O2/c20-18(21)17-3-1-2-16(23-17)14-4-9-24(10-5-14)11-8-22-19(25)15-6-12-26-13-7-15/h1-3,14-15,18H,4-13H2,(H,22,25)
PDB

Reactome pathway

UniProtKB/SwissProt
UniProtKB/TrEMBL

antibodypedia
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 10n/an/an/an/an/an/a



SUMITOMO DAINIPPON PHARMA CO., LTD.

US Patent


Assay Description
The binding affinity of the present compounds to human 5-HT1A receptor, human D4 receptor, and human D2 receptor was measured in a manner mentioned b...


US Patent US10800755 (2020)

More data for this
Ligand-Target Pair
D(4) dopamine receptor


(Homo sapiens)
BDBM466584
PNG
(N-(2-{4-[6-(Dimethylamino)pyridin-2-yl]piperidin-1...)
Show SMILES CN(C)c1cccc(n1)C1CCN(CCNC(=O)C2CCOCC2)CC1
Show InChI InChI=1S/C20H32N4O2/c1-23(2)19-5-3-4-18(22-19)16-6-11-24(12-7-16)13-10-21-20(25)17-8-14-26-15-9-17/h3-5,16-17H,6-15H2,1-2H3,(H,21,25)
Reactome pathway

UniProtKB/TrEMBL

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 10n/an/an/an/an/an/a



SUMITOMO DAINIPPON PHARMA CO., LTD.

US Patent


Assay Description
The binding affinity of the present compounds to human 5-HT1A receptor, human D4 receptor, and human D2 receptor was measured in a manner mentioned b...


US Patent US10800755 (2020)

More data for this
Ligand-Target Pair
D(4) dopamine receptor


(Homo sapiens)
BDBM466535
PNG
(4,4-Difluoro-N-(2-{4-[6-(trifluoromethyl)pyridin-2...)
Show SMILES FC(F)(F)c1cccc(n1)C1CCN(CCNC(=O)C2CCC(F)(F)CC2)CC1
Show InChI InChI=1S/C20H26F5N3O/c21-19(22)8-4-15(5-9-19)18(29)26-10-13-28-11-6-14(7-12-28)16-2-1-3-17(27-16)20(23,24)25/h1-3,14-15H,4-13H2,(H,26,29)
Reactome pathway

UniProtKB/TrEMBL

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 11n/an/an/an/an/an/a



SUMITOMO DAINIPPON PHARMA CO., LTD.

US Patent


Assay Description
The binding affinity of the present compounds to human 5-HT1A receptor, human D4 receptor, and human D2 receptor was measured in a manner mentioned b...


US Patent US10800755 (2020)

More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Homo sapiens (Human))
BDBM466540
PNG
(US10800755, Example 2)
Show SMILES FC(F)(F)c1cccc(n1)C1CCN(CCNC(=O)C2CCCOC2)CC1
Show InChI InChI=1S/C19H26F3N3O2/c20-19(21,22)17-5-1-4-16(24-17)14-6-9-25(10-7-14)11-8-23-18(26)15-3-2-12-27-13-15/h1,4-5,14-15H,2-3,6-13H2,(H,23,26)
PDB

Reactome pathway

UniProtKB/SwissProt
UniProtKB/TrEMBL

antibodypedia
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 11n/an/an/an/an/an/a



SUMITOMO DAINIPPON PHARMA CO., LTD.

US Patent


Assay Description
The binding affinity of the present compounds to human 5-HT1A receptor, human D4 receptor, and human D2 receptor was measured in a manner mentioned b...


US Patent US10800755 (2020)

More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Homo sapiens (Human))
BDBM466551
PNG
(US10800755, Example 7)
Show SMILES COCC1(CC1)C(=O)NCCN1CCC(CC1)c1cccc(n1)C(F)(F)F
Show InChI InChI=1S/C19H26F3N3O2/c1-27-13-18(7-8-18)17(26)23-9-12-25-10-5-14(6-11-25)15-3-2-4-16(24-15)19(20,21)22/h2-4,14H,5-13H2,1H3,(H,23,26)
PDB

Reactome pathway

UniProtKB/SwissProt
UniProtKB/TrEMBL

antibodypedia
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 13n/an/an/an/an/an/a



SUMITOMO DAINIPPON PHARMA CO., LTD.

US Patent


Assay Description
The binding affinity of the present compounds to human 5-HT1A receptor, human D4 receptor, and human D2 receptor was measured in a manner mentioned b...


US Patent US10800755 (2020)

More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Homo sapiens (Human))
BDBM466560
PNG
(US10800755, Example 15)
Show SMILES Cc1cccc(n1)C1CCN(CCNC(=O)C2CCCOC2)CC1
Show InChI InChI=1S/C19H29N3O2/c1-15-4-2-6-18(21-15)16-7-10-22(11-8-16)12-9-20-19(23)17-5-3-13-24-14-17/h2,4,6,16-17H,3,5,7-14H2,1H3,(H,20,23)
PDB

Reactome pathway

UniProtKB/SwissProt
UniProtKB/TrEMBL

antibodypedia
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 13n/an/an/an/an/an/a



SUMITOMO DAINIPPON PHARMA CO., LTD.

US Patent


Assay Description
The binding affinity of the present compounds to human 5-HT1A receptor, human D4 receptor, and human D2 receptor was measured in a manner mentioned b...


US Patent US10800755 (2020)

More data for this
Ligand-Target Pair
D(4) dopamine receptor


(Homo sapiens)
BDBM466576
PNG
(2,2-Dimethyl-N-[2-(6-methyl-3′,6′-dihy...)
Show SMILES Cc1cccc(n1)C1=CCN(CCNC(=O)C(C)(C)C)CC1
Show InChI InChI=1S/C18H27N3O/c1-14-6-5-7-16(20-14)15-8-11-21(12-9-15)13-10-19-17(22)18(2,3)4/h5-8H,9-13H2,1-4H3,(H,19,22)
Reactome pathway

UniProtKB/TrEMBL

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 14n/an/an/an/an/an/a



SUMITOMO DAINIPPON PHARMA CO., LTD.

US Patent


Assay Description
The binding affinity of the present compounds to human 5-HT1A receptor, human D4 receptor, and human D2 receptor was measured in a manner mentioned b...


US Patent US10800755 (2020)

More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Homo sapiens (Human))
BDBM466567
PNG
(US10800755, Example 21)
Show SMILES FC(F)(F)c1cccc(n1)C1CCN(CCNC(=O)[C@H]2C[C@@H]3CC[C@H]2O3)CC1
Show InChI InChI=1S/C20H26F3N3O2/c21-20(22,23)18-3-1-2-16(25-18)13-6-9-26(10-7-13)11-8-24-19(27)15-12-14-4-5-17(15)28-14/h1-3,13-15,17H,4-12H2,(H,24,27)/t14-,15-,17+/m0/s1
PDB

Reactome pathway

UniProtKB/SwissProt
UniProtKB/TrEMBL

antibodypedia
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 15n/an/an/an/an/an/a



SUMITOMO DAINIPPON PHARMA CO., LTD.

US Patent


Assay Description
The binding affinity of the present compounds to human 5-HT1A receptor, human D4 receptor, and human D2 receptor was measured in a manner mentioned b...


US Patent US10800755 (2020)

More data for this
Ligand-Target Pair
D(4) dopamine receptor


(Homo sapiens)
BDBM466564
PNG
(US10800755, Example 18)
Show SMILES COCC(C)(C)C(=O)NCCN1CCC(=CC1)c1cccc(n1)C(F)(F)F
Show InChI InChI=1S/C19H26F3N3O2/c1-18(2,13-27-3)17(26)23-9-12-25-10-7-14(8-11-25)15-5-4-6-16(24-15)19(20,21)22/h4-7H,8-13H2,1-3H3,(H,23,26)
Reactome pathway

UniProtKB/TrEMBL

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 19n/an/an/an/an/an/a



SUMITOMO DAINIPPON PHARMA CO., LTD.

US Patent


Assay Description
The binding affinity of the present compounds to human 5-HT1A receptor, human D4 receptor, and human D2 receptor was measured in a manner mentioned b...


US Patent US10800755 (2020)

More data for this
Ligand-Target Pair
D(4) dopamine receptor


(Homo sapiens)
BDBM466554
PNG
(US10800755, Example 10)
Show SMILES Cc1cccc(n1)C1CCN(CCNC(=O)C(C)(C)C)CC1
Show InChI InChI=1S/C18H29N3O/c1-14-6-5-7-16(20-14)15-8-11-21(12-9-15)13-10-19-17(22)18(2,3)4/h5-7,15H,8-13H2,1-4H3,(H,19,22)
Reactome pathway

UniProtKB/TrEMBL

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 19n/an/an/an/an/an/a



SUMITOMO DAINIPPON PHARMA CO., LTD.

US Patent


Assay Description
The binding affinity of the present compounds to human 5-HT1A receptor, human D4 receptor, and human D2 receptor was measured in a manner mentioned b...


US Patent US10800755 (2020)

More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Homo sapiens (Human))
BDBM466571
PNG
(US10800755, Example 25)
Show SMILES FC(F)(F)c1cccc(n1)C1CCN(CCNC(=O)C2CCCO2)CC1
Show InChI InChI=1S/C18H24F3N3O2/c19-18(20,21)16-5-1-3-14(23-16)13-6-9-24(10-7-13)11-8-22-17(25)15-4-2-12-26-15/h1,3,5,13,15H,2,4,6-12H2,(H,22,25)
PDB

Reactome pathway

UniProtKB/SwissProt
UniProtKB/TrEMBL

antibodypedia
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 20n/an/an/an/an/an/a



SUMITOMO DAINIPPON PHARMA CO., LTD.

US Patent


Assay Description
The binding affinity of the present compounds to human 5-HT1A receptor, human D4 receptor, and human D2 receptor was measured in a manner mentioned b...


US Patent US10800755 (2020)

More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Homo sapiens (Human))
BDBM466579
PNG
(US10800755, Example 33)
Show SMILES COc1cccc(n1)C1CCN(CCNC(=O)C2CCOCC2)CC1
Show InChI InChI=1S/C19H29N3O3/c1-24-18-4-2-3-17(21-18)15-5-10-22(11-6-15)12-9-20-19(23)16-7-13-25-14-8-16/h2-4,15-16H,5-14H2,1H3,(H,20,23)
PDB

Reactome pathway

UniProtKB/SwissProt
UniProtKB/TrEMBL

antibodypedia
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 21n/an/an/an/an/an/a



SUMITOMO DAINIPPON PHARMA CO., LTD.

US Patent


Assay Description
The binding affinity of the present compounds to human 5-HT1A receptor, human D4 receptor, and human D2 receptor was measured in a manner mentioned b...


US Patent US10800755 (2020)

More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Homo sapiens (Human))
BDBM466564
PNG
(US10800755, Example 18)
Show SMILES COCC(C)(C)C(=O)NCCN1CCC(=CC1)c1cccc(n1)C(F)(F)F
Show InChI InChI=1S/C19H26F3N3O2/c1-18(2,13-27-3)17(26)23-9-12-25-10-7-14(8-11-25)15-5-4-6-16(24-15)19(20,21)22/h4-7H,8-13H2,1-3H3,(H,23,26)
PDB

Reactome pathway

UniProtKB/SwissProt
UniProtKB/TrEMBL

antibodypedia
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 21n/an/an/an/an/an/a



SUMITOMO DAINIPPON PHARMA CO., LTD.

US Patent


Assay Description
The binding affinity of the present compounds to human 5-HT1A receptor, human D4 receptor, and human D2 receptor was measured in a manner mentioned b...


US Patent US10800755 (2020)

More data for this
Ligand-Target Pair
D(4) dopamine receptor


(Homo sapiens)
BDBM466575
PNG
(N-[2-(6-Methyl-3′,6′-dihydro[2,4′...)
Show SMILES Cc1cccc(n1)C1=CCN(CCNC(=O)C2CCOCC2)CC1
Show InChI InChI=1S/C19H27N3O2/c1-15-3-2-4-18(21-15)16-5-10-22(11-6-16)12-9-20-19(23)17-7-13-24-14-8-17/h2-5,17H,6-14H2,1H3,(H,20,23)
Reactome pathway

UniProtKB/TrEMBL

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 22n/an/an/an/an/an/a



SUMITOMO DAINIPPON PHARMA CO., LTD.

US Patent


Assay Description
The binding affinity of the present compounds to human 5-HT1A receptor, human D4 receptor, and human D2 receptor was measured in a manner mentioned b...


US Patent US10800755 (2020)

More data for this
Ligand-Target Pair
D(4) dopamine receptor


(Homo sapiens)
BDBM466557
PNG
(US10800755, Example 13)
Show SMILES Cc1cccc(n1)C1=CCN(CCNC(=O)[C@H]2C[C@@H]3CC[C@H]2O3)CC1
Show InChI InChI=1S/C20H27N3O2/c1-14-3-2-4-18(22-14)15-7-10-23(11-8-15)12-9-21-20(24)17-13-16-5-6-19(17)25-16/h2-4,7,16-17,19H,5-6,8-13H2,1H3,(H,21,24)/t16-,17-,19+/m0/s1
Reactome pathway

UniProtKB/TrEMBL

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 24n/an/an/an/an/an/a



SUMITOMO DAINIPPON PHARMA CO., LTD.

US Patent


Assay Description
The binding affinity of the present compounds to human 5-HT1A receptor, human D4 receptor, and human D2 receptor was measured in a manner mentioned b...


US Patent US10800755 (2020)

More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Homo sapiens (Human))
BDBM466562
PNG
(US10800755, Example 17)
Show SMILES COCC(C)(C)C(=O)NCCN1CCC(=CC1)c1cccc(C)n1
Show InChI InChI=1S/C19H29N3O2/c1-15-6-5-7-17(21-15)16-8-11-22(12-9-16)13-10-20-18(23)19(2,3)14-24-4/h5-8H,9-14H2,1-4H3,(H,20,23)
PDB

Reactome pathway

UniProtKB/SwissProt
UniProtKB/TrEMBL

antibodypedia
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 26n/an/an/an/an/an/a



SUMITOMO DAINIPPON PHARMA CO., LTD.

US Patent


Assay Description
The binding affinity of the present compounds to human 5-HT1A receptor, human D4 receptor, and human D2 receptor was measured in a manner mentioned b...


US Patent US10800755 (2020)

More data for this
Ligand-Target Pair
D(4) dopamine receptor


(Homo sapiens)
BDBM466547
PNG
(US10800755, Example 4)
Show SMILES Cc1cccc(n1)C1CCN(CCNC(=O)C2CCC(F)(F)CC2)CC1
Show InChI InChI=1S/C20H29F2N3O/c1-15-3-2-4-18(24-15)16-7-12-25(13-8-16)14-11-23-19(26)17-5-9-20(21,22)10-6-17/h2-4,16-17H,5-14H2,1H3,(H,23,26)
Reactome pathway

UniProtKB/TrEMBL

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 26n/an/an/an/an/an/a



SUMITOMO DAINIPPON PHARMA CO., LTD.

US Patent


Assay Description
The binding affinity of the present compounds to human 5-HT1A receptor, human D4 receptor, and human D2 receptor was measured in a manner mentioned b...


US Patent US10800755 (2020)

More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Homo sapiens (Human))
BDBM466570
PNG
(US10800755, Example 24)
Show SMILES Cc1cccc(n1)C1CCN(CCNC(=O)C2CCCO2)CC1
Show InChI InChI=1S/C18H27N3O2/c1-14-4-2-5-16(20-14)15-7-10-21(11-8-15)12-9-19-18(22)17-6-3-13-23-17/h2,4-5,15,17H,3,6-13H2,1H3,(H,19,22)
PDB

Reactome pathway

UniProtKB/SwissProt
UniProtKB/TrEMBL

antibodypedia
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 27n/an/an/an/an/an/a



SUMITOMO DAINIPPON PHARMA CO., LTD.

US Patent


Assay Description
The binding affinity of the present compounds to human 5-HT1A receptor, human D4 receptor, and human D2 receptor was measured in a manner mentioned b...


US Patent US10800755 (2020)

More data for this
Ligand-Target Pair
D(4) dopamine receptor


(Homo sapiens)
BDBM466561
PNG
(N-{2-[6-(Trifluoromethyl)-3′,6′-dihydr...)
Show SMILES FC(F)(F)c1cccc(n1)C1=CCN(CCNC(=O)C2CCCOC2)CC1
Show InChI InChI=1S/C19H24F3N3O2/c20-19(21,22)17-5-1-4-16(24-17)14-6-9-25(10-7-14)11-8-23-18(26)15-3-2-12-27-13-15/h1,4-6,15H,2-3,7-13H2,(H,23,26)
Reactome pathway

UniProtKB/TrEMBL

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 27n/an/an/an/an/an/a



SUMITOMO DAINIPPON PHARMA CO., LTD.

US Patent


Assay Description
The binding affinity of the present compounds to human 5-HT1A receptor, human D4 receptor, and human D2 receptor was measured in a manner mentioned b...


US Patent US10800755 (2020)

More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Homo sapiens (Human))
BDBM466574
PNG
(US10800755, Example 28)
Show SMILES FC(F)(F)Oc1cccc(n1)C1CCN(CCNC(=O)C2CCOCC2)CC1
Show InChI InChI=1S/C19H26F3N3O3/c20-19(21,22)28-17-3-1-2-16(24-17)14-4-9-25(10-5-14)11-8-23-18(26)15-6-12-27-13-7-15/h1-3,14-15H,4-13H2,(H,23,26)
PDB

Reactome pathway

UniProtKB/SwissProt
UniProtKB/TrEMBL

antibodypedia
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 28n/an/an/an/an/an/a



SUMITOMO DAINIPPON PHARMA CO., LTD.

US Patent


Assay Description
The binding affinity of the present compounds to human 5-HT1A receptor, human D4 receptor, and human D2 receptor was measured in a manner mentioned b...


US Patent US10800755 (2020)

More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Homo sapiens (Human))
BDBM466550
PNG
(US10800755, Example 6)
Show SMILES COCC(C)(C)C(=O)NCCN1CCC(CC1)c1cccc(n1)C(F)(F)F
Show InChI InChI=1S/C19H28F3N3O2/c1-18(2,13-27-3)17(26)23-9-12-25-10-7-14(8-11-25)15-5-4-6-16(24-15)19(20,21)22/h4-6,14H,7-13H2,1-3H3,(H,23,26)
PDB

Reactome pathway

UniProtKB/SwissProt
UniProtKB/TrEMBL

antibodypedia
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 37n/an/an/an/an/an/a



SUMITOMO DAINIPPON PHARMA CO., LTD.

US Patent


Assay Description
The binding affinity of the present compounds to human 5-HT1A receptor, human D4 receptor, and human D2 receptor was measured in a manner mentioned b...


US Patent US10800755 (2020)

More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Homo sapiens (Human))
BDBM466584
PNG
(N-(2-{4-[6-(Dimethylamino)pyridin-2-yl]piperidin-1...)
Show SMILES CN(C)c1cccc(n1)C1CCN(CCNC(=O)C2CCOCC2)CC1
Show InChI InChI=1S/C20H32N4O2/c1-23(2)19-5-3-4-18(22-19)16-6-11-24(12-7-16)13-10-21-20(25)17-8-14-26-15-9-17/h3-5,16-17H,6-15H2,1-2H3,(H,21,25)
PDB

Reactome pathway

UniProtKB/SwissProt
UniProtKB/TrEMBL

antibodypedia
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 37n/an/an/an/an/an/a



SUMITOMO DAINIPPON PHARMA CO., LTD.

US Patent


Assay Description
The binding affinity of the present compounds to human 5-HT1A receptor, human D4 receptor, and human D2 receptor was measured in a manner mentioned b...


US Patent US10800755 (2020)

More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Homo sapiens (Human))
BDBM466578
PNG
(US10800755, Example 32)
Show SMILES Fc1cccc(n1)C1CCN(CCNC(=O)C2CCOCC2)CC1
Show InChI InChI=1S/C18H26FN3O2/c19-17-3-1-2-16(21-17)14-4-9-22(10-5-14)11-8-20-18(23)15-6-12-24-13-7-15/h1-3,14-15H,4-13H2,(H,20,23)
PDB

Reactome pathway

UniProtKB/SwissProt
UniProtKB/TrEMBL

antibodypedia
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 42n/an/an/an/an/an/a



SUMITOMO DAINIPPON PHARMA CO., LTD.

US Patent


Assay Description
The binding affinity of the present compounds to human 5-HT1A receptor, human D4 receptor, and human D2 receptor was measured in a manner mentioned b...


US Patent US10800755 (2020)

More data for this
Ligand-Target Pair
D(4) dopamine receptor


(Homo sapiens)
BDBM466551
PNG
(US10800755, Example 7)
Show SMILES COCC1(CC1)C(=O)NCCN1CCC(CC1)c1cccc(n1)C(F)(F)F
Show InChI InChI=1S/C19H26F3N3O2/c1-27-13-18(7-8-18)17(26)23-9-12-25-10-5-14(6-11-25)15-3-2-4-16(24-15)19(20,21)22/h2-4,14H,5-13H2,1H3,(H,23,26)
Reactome pathway

UniProtKB/TrEMBL

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 43n/an/an/an/an/an/a



SUMITOMO DAINIPPON PHARMA CO., LTD.

US Patent


Assay Description
The binding affinity of the present compounds to human 5-HT1A receptor, human D4 receptor, and human D2 receptor was measured in a manner mentioned b...


US Patent US10800755 (2020)

More data for this
Ligand-Target Pair
D(4) dopamine receptor


(Homo sapiens)
BDBM466555
PNG
(US10800755, Example 11)
Show SMILES FC(F)(F)c1cccc(n1)C1CCN(CCNC(=O)C2CCOCC2)CC1
Show InChI InChI=1S/C19H26F3N3O2/c20-19(21,22)17-3-1-2-16(24-17)14-4-9-25(10-5-14)11-8-23-18(26)15-6-12-27-13-7-15/h1-3,14-15H,4-13H2,(H,23,26)
Reactome pathway

UniProtKB/TrEMBL

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 44n/an/an/an/an/an/a



SUMITOMO DAINIPPON PHARMA CO., LTD.

US Patent


Assay Description
The binding affinity of the present compounds to human 5-HT1A receptor, human D4 receptor, and human D2 receptor was measured in a manner mentioned b...


US Patent US10800755 (2020)

More data for this
Ligand-Target Pair
D(4) dopamine receptor


(Homo sapiens)
BDBM466580
PNG
(US10800755, Example 34)
Show SMILES FC(F)c1cccc(n1)C1CCN(CCNC(=O)C2CCOCC2)CC1
Show InChI InChI=1S/C19H27F2N3O2/c20-18(21)17-3-1-2-16(23-17)14-4-9-24(10-5-14)11-8-22-19(25)15-6-12-26-13-7-15/h1-3,14-15,18H,4-13H2,(H,22,25)
Reactome pathway

UniProtKB/TrEMBL

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 56n/an/an/an/an/an/a



SUMITOMO DAINIPPON PHARMA CO., LTD.

US Patent


Assay Description
The binding affinity of the present compounds to human 5-HT1A receptor, human D4 receptor, and human D2 receptor was measured in a manner mentioned b...


US Patent US10800755 (2020)

More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Homo sapiens (Human))
BDBM466568
PNG
(US10800755, Example 22)
Show SMILES Cc1cccc(n1)C1CCN(CCNC(=O)C2CCOC2)CC1
Show InChI InChI=1S/C18H27N3O2/c1-14-3-2-4-17(20-14)15-5-9-21(10-6-15)11-8-19-18(22)16-7-12-23-13-16/h2-4,15-16H,5-13H2,1H3,(H,19,22)
PDB

Reactome pathway

UniProtKB/SwissProt
UniProtKB/TrEMBL

antibodypedia
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 58n/an/an/an/an/an/a



SUMITOMO DAINIPPON PHARMA CO., LTD.

US Patent


Assay Description
The binding affinity of the present compounds to human 5-HT1A receptor, human D4 receptor, and human D2 receptor was measured in a manner mentioned b...


US Patent US10800755 (2020)

More data for this
Ligand-Target Pair
D(4) dopamine receptor


(Homo sapiens)
BDBM466583
PNG
(N-(2-{4-[6-(Methylamino)pyridin-2-yl]piperidin-1-y...)
Show SMILES CNc1cccc(n1)C1CCN(CCNC(=O)C2CCOCC2)CC1
Show InChI InChI=1S/C19H30N4O2/c1-20-18-4-2-3-17(22-18)15-5-10-23(11-6-15)12-9-21-19(24)16-7-13-25-14-8-16/h2-4,15-16H,5-14H2,1H3,(H,20,22)(H,21,24)
Reactome pathway

UniProtKB/TrEMBL

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 73n/an/an/an/an/an/a



SUMITOMO DAINIPPON PHARMA CO., LTD.

US Patent


Assay Description
The binding affinity of the present compounds to human 5-HT1A receptor, human D4 receptor, and human D2 receptor was measured in a manner mentioned b...


US Patent US10800755 (2020)

More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Homo sapiens (Human))
BDBM466573
PNG
(US10800755, Example 27)
Show SMILES CO[C@H]1CC[C@@H](CC1)C(=O)NCCN1CCC(CC1)c1cccc(n1)C(F)(F)F
Show InChI InChI=1S/C21H30F3N3O2/c1-29-17-7-5-16(6-8-17)20(28)25-11-14-27-12-9-15(10-13-27)18-3-2-4-19(26-18)21(22,23)24/h2-4,15-17H,5-14H2,1H3,(H,25,28)/t16-,17-
PDB

Reactome pathway

UniProtKB/SwissProt
UniProtKB/TrEMBL

antibodypedia
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 77n/an/an/an/an/an/a



SUMITOMO DAINIPPON PHARMA CO., LTD.

US Patent


Assay Description
The binding affinity of the present compounds to human 5-HT1A receptor, human D4 receptor, and human D2 receptor was measured in a manner mentioned b...


US Patent US10800755 (2020)

More data for this
Ligand-Target Pair
Displayed 1 to 50 (of 217 total )  |  Next  |  Last  >>
* indicates data uncertainty>20%