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Patent code US10807959

Compile Data Set for Download or QSAR

Found 266 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
WD repeat-containing protein 5 (WDR5)


(Homo sapiens (Human))
BDBM468736
PNG
(US10807959, Example 5)
Show SMILES Cc1cc(CNC(=O)c2cc(CNC3=NCCN3)cc(c2)-c2ccc(F)nc2C)ccc1Cl
Show InChI InChI=1S/C25H25ClFN5O/c1-15-9-17(3-5-22(15)26)13-30-24(33)20-11-18(14-31-25-28-7-8-29-25)10-19(12-20)21-4-6-23(27)32-16(21)2/h3-6,9-12H,7-8,13-14H2,1-2H3,(H,30,33)(H2,28,29,31)
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0.0200n/an/an/an/an/an/an/an/a



Vanderbilt University

US Patent


Assay Description
A Time-Resolved Fluorescence Resonance Energy Transfer (TR-FRET) assay that measures the displacement of the 10mer-Thr-FAM probe in response to compo...


US Patent US10807959 (2020)

More data for this
Ligand-Target Pair
WD repeat-containing protein 5 (WDR5)


(Homo sapiens (Human))
BDBM468925
PNG
(US10807959, Example B64)
Show SMILES Cc1nc(F)ccc1-c1cc(CNC2=NCCN2)cc(c1)C(=O)NCc1ccc(Cl)c(Cl)c1
Show InChI InChI=1S/C24H22Cl2FN5O/c1-14-19(3-5-22(27)32-14)17-8-16(13-31-24-28-6-7-29-24)9-18(11-17)23(33)30-12-15-2-4-20(25)21(26)10-15/h2-5,8-11H,6-7,12-13H2,1H3,(H,30,33)(H2,28,29,31)
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0.0210n/an/an/an/an/an/an/an/a



Vanderbilt University

US Patent


Assay Description
FPA Assay protocol adopted from Karatas et al. (J. Med. Chem. 2010, 5179.; J. Amer. Chem. Soc. 2013, 669.): WDR5 (Δ23, residues 24-334), is expr...


US Patent US10807959 (2020)

More data for this
Ligand-Target Pair
WD repeat-containing protein 5 (WDR5)


(Homo sapiens (Human))
BDBM468927
PNG
(US10807959, Example B74)
Show SMILES Cc1cc(ccn1)-c1cc(CNC2=NCCN2)cc(c1)C(=O)NCc1ccc(Cl)c(Cl)c1
Show InChI InChI=1S/C24H23Cl2N5O/c1-15-8-18(4-5-27-15)19-9-17(14-31-24-28-6-7-29-24)10-20(12-19)23(32)30-13-16-2-3-21(25)22(26)11-16/h2-5,8-12H,6-7,13-14H2,1H3,(H,30,32)(H2,28,29,31)
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0.0310n/an/an/an/an/an/an/an/a



Vanderbilt University

US Patent


Assay Description
FPA Assay protocol adopted from Karatas et al. (J. Med. Chem. 2010, 5179.; J. Amer. Chem. Soc. 2013, 669.): WDR5 (Δ23, residues 24-334), is expr...


US Patent US10807959 (2020)

More data for this
Ligand-Target Pair
WD repeat-containing protein 5 (WDR5)


(Homo sapiens (Human))
BDBM468928
PNG
(US10807959, Example B81)
Show SMILES Cc1cc(ccn1)-c1cc(CNC2=NCCN2)cc(c1)C(=O)NCc1cc(Cl)cc(Cl)c1
Show InChI InChI=1S/C24H23Cl2N5O/c1-15-6-18(2-3-27-15)19-7-16(14-31-24-28-4-5-29-24)8-20(11-19)23(32)30-13-17-9-21(25)12-22(26)10-17/h2-3,6-12H,4-5,13-14H2,1H3,(H,30,32)(H2,28,29,31)
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0.0330n/an/an/an/an/an/an/an/a



Vanderbilt University

US Patent


Assay Description
FPA Assay protocol adopted from Karatas et al. (J. Med. Chem. 2010, 5179.; J. Amer. Chem. Soc. 2013, 669.): WDR5 (Δ23, residues 24-334), is expr...


US Patent US10807959 (2020)

More data for this
Ligand-Target Pair
WD repeat-containing protein 5 (WDR5)


(Homo sapiens (Human))
BDBM468938
PNG
(US10807959, Example B109)
Show SMILES COc1cc(CNC(=O)c2cc(CNC3=NCCN3)cc(c2)-c2cc(C)cnc2F)cc(OC)c1
Show InChI InChI=1S/C26H28FN5O3/c1-16-6-23(24(27)30-13-16)19-7-17(15-32-26-28-4-5-29-26)8-20(11-19)25(33)31-14-18-9-21(34-2)12-22(10-18)35-3/h6-13H,4-5,14-15H2,1-3H3,(H,31,33)(H2,28,29,32)
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0.0380n/an/an/an/an/an/an/an/a



Vanderbilt University

US Patent


Assay Description
FPA Assay protocol adopted from Karatas et al. (J. Med. Chem. 2010, 5179.; J. Amer. Chem. Soc. 2013, 669.): WDR5 (Δ23, residues 24-334), is expr...


US Patent US10807959 (2020)

More data for this
Ligand-Target Pair
WD repeat-containing protein 5 (WDR5)


(Homo sapiens (Human))
BDBM468939
PNG
(US10807959, Example B111)
Show SMILES Cc1cc(cc(C)n1)-c1cc(CNC2=NCCN2)cc(c1)C(=O)NCc1cc(Cl)ccn1
Show InChI InChI=1S/C24H25ClN6O/c1-15-7-18(8-16(2)31-15)19-9-17(13-30-24-27-5-6-28-24)10-20(11-19)23(32)29-14-22-12-21(25)3-4-26-22/h3-4,7-12H,5-6,13-14H2,1-2H3,(H,29,32)(H2,27,28,30)
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0.0870n/an/an/an/an/an/an/an/a



Vanderbilt University

US Patent


Assay Description
FPA Assay protocol adopted from Karatas et al. (J. Med. Chem. 2010, 5179.; J. Amer. Chem. Soc. 2013, 669.): WDR5 (Δ23, residues 24-334), is expr...


US Patent US10807959 (2020)

More data for this
Ligand-Target Pair
WD repeat-containing protein 5 (WDR5)


(Homo sapiens (Human))
BDBM468936
PNG
(US10807959, Example B99)
Show SMILES Cc1cc(cnc1F)-c1cc(CNC2=NCCN2)cc(c1)C(=O)NCc1ccc(Cl)c(Cl)c1
Show InChI InChI=1S/C24H22Cl2FN5O/c1-14-6-19(13-30-22(14)27)17-7-16(12-32-24-28-4-5-29-24)8-18(10-17)23(33)31-11-15-2-3-20(25)21(26)9-15/h2-3,6-10,13H,4-5,11-12H2,1H3,(H,31,33)(H2,28,29,32)
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0.0870n/an/an/an/an/an/an/an/a



Vanderbilt University

US Patent


Assay Description
FPA Assay protocol adopted from Karatas et al. (J. Med. Chem. 2010, 5179.; J. Amer. Chem. Soc. 2013, 669.): WDR5 (Δ23, residues 24-334), is expr...


US Patent US10807959 (2020)

More data for this
Ligand-Target Pair
WD repeat-containing protein 5 (WDR5)


(Homo sapiens (Human))
BDBM468945
PNG
(US10807959, Example B129)
Show SMILES Cc1cc(CNC(=O)c2cc(CNC3=NCCC3)cc(c2)-c2ccc(F)nc2C)ccc1Cl
Show InChI InChI=1S/C26H26ClFN4O/c1-16-10-18(5-7-23(16)27)14-31-26(33)21-12-19(15-30-25-4-3-9-29-25)11-20(13-21)22-6-8-24(28)32-17(22)2/h5-8,10-13H,3-4,9,14-15H2,1-2H3,(H,29,30)(H,31,33)
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0.0890n/an/an/an/an/an/an/an/a



Vanderbilt University

US Patent


Assay Description
FPA Assay protocol adopted from Karatas et al. (J. Med. Chem. 2010, 5179.; J. Amer. Chem. Soc. 2013, 669.): WDR5 (Δ23, residues 24-334), is expr...


US Patent US10807959 (2020)

More data for this
Ligand-Target Pair
WD repeat-containing protein 5 (WDR5)


(Homo sapiens (Human))
BDBM468937
PNG
(US10807959, Example B107)
Show SMILES COc1ccc(CNC(=O)c2cc(CNC3=NCCN3)cc(c2)-c2cc(C)cnc2F)cc1OC
Show InChI InChI=1S/C26H28FN5O3/c1-16-8-21(24(27)30-13-16)19-9-18(15-32-26-28-6-7-29-26)10-20(12-19)25(33)31-14-17-4-5-22(34-2)23(11-17)35-3/h4-5,8-13H,6-7,14-15H2,1-3H3,(H,31,33)(H2,28,29,32)
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0.0970n/an/an/an/an/an/an/an/a



Vanderbilt University

US Patent


Assay Description
FPA Assay protocol adopted from Karatas et al. (J. Med. Chem. 2010, 5179.; J. Amer. Chem. Soc. 2013, 669.): WDR5 (Δ23, residues 24-334), is expr...


US Patent US10807959 (2020)

More data for this
Ligand-Target Pair
WD repeat-containing protein 5 (WDR5)


(Homo sapiens (Human))
BDBM468770
PNG
(US10807959, Example 39)
Show SMILES Cc1ccnc(c1)C(NC(=O)c1cc(CNC2=NCCN2)cc(c1)-c1cc(C)cnc1F)C1CC1
Show InChI InChI=1S/C27H29FN6O/c1-16-5-6-29-23(10-16)24(19-3-4-19)34-26(35)21-12-18(15-33-27-30-7-8-31-27)11-20(13-21)22-9-17(2)14-32-25(22)28/h5-6,9-14,19,24H,3-4,7-8,15H2,1-2H3,(H,34,35)(H2,30,31,33)
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<0.100n/an/an/an/an/an/an/an/a



Vanderbilt University

US Patent


Assay Description
A Time-Resolved Fluorescence Resonance Energy Transfer (TR-FRET) assay that measures the displacement of the 10mer-Thr-FAM probe in response to compo...


US Patent US10807959 (2020)

More data for this
Ligand-Target Pair
WD repeat-containing protein 5 (WDR5)


(Homo sapiens (Human))
BDBM468762
PNG
(US10807959, Example 31)
Show SMILES Cc1cc(CNC(=O)c2cc(CNC3=NCCN3)cc(c2)-c2cnc(F)c(C)c2)ccc1Cl
Show InChI InChI=1S/C25H25ClFN5O/c1-15-7-17(3-4-22(15)26)12-31-24(33)20-10-18(13-32-25-28-5-6-29-25)9-19(11-20)21-8-16(2)23(27)30-14-21/h3-4,7-11,14H,5-6,12-13H2,1-2H3,(H,31,33)(H2,28,29,32)
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Vanderbilt University

US Patent


Assay Description
A Time-Resolved Fluorescence Resonance Energy Transfer (TR-FRET) assay that measures the displacement of the 10mer-Thr-FAM probe in response to compo...


US Patent US10807959 (2020)

More data for this
Ligand-Target Pair
WD repeat-containing protein 5 (WDR5)


(Homo sapiens (Human))
BDBM468836
PNG
(US10807959, Example 106)
Show SMILES CCn1cc(c(n1)C(F)(F)F)-c1cc(CNC(=N)C2CCC2)cc(c1)C(=O)N[C@@H](C1CC1)c1ccc(F)c(C)c1
Show InChI InChI=1S/C30H33F4N5O/c1-3-39-16-24(27(38-39)30(32,33)34)22-12-18(15-36-28(35)20-5-4-6-20)13-23(14-22)29(40)37-26(19-7-8-19)21-9-10-25(31)17(2)11-21/h9-14,16,19-20,26H,3-8,15H2,1-2H3,(H2,35,36)(H,37,40)/t26-/m0/s1
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<0.100n/an/an/an/an/an/an/an/a



Vanderbilt University

US Patent


Assay Description
A Time-Resolved Fluorescence Resonance Energy Transfer (TR-FRET) assay that measures the displacement of the 10mer-Thr-FAM probe in response to compo...


US Patent US10807959 (2020)

More data for this
Ligand-Target Pair
WD repeat-containing protein 5 (WDR5)


(Homo sapiens (Human))
BDBM468835
PNG
(US10807959, Example 105)
Show SMILES CCn1cc(c(n1)C(F)(F)F)-c1cc(CNC(=N)C2CC2)cc(c1)C(=O)N[C@@H](C1CC1)c1ccc(F)c(C)c1
Show InChI InChI=1S/C29H31F4N5O/c1-3-38-15-23(26(37-38)29(31,32)33)21-11-17(14-35-27(34)19-6-7-19)12-22(13-21)28(39)36-25(18-4-5-18)20-8-9-24(30)16(2)10-20/h8-13,15,18-19,25H,3-7,14H2,1-2H3,(H2,34,35)(H,36,39)/t25-/m0/s1
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<0.100n/an/an/an/an/an/an/an/a



Vanderbilt University

US Patent


Assay Description
A Time-Resolved Fluorescence Resonance Energy Transfer (TR-FRET) assay that measures the displacement of the 10mer-Thr-FAM probe in response to compo...


US Patent US10807959 (2020)

More data for this
Ligand-Target Pair
WD repeat-containing protein 5 (WDR5)


(Homo sapiens (Human))
BDBM468817
PNG
(US10807959, Example 87)
Show SMILES COc1ccc(C)cc1-c1cc(CNC2=NCCN2)cc(n1)C(=O)NCc1ccc(Cl)c(Cl)c1
Show InChI InChI=1S/C25H25Cl2N5O2/c1-15-3-6-23(34-2)18(9-15)21-11-17(14-31-25-28-7-8-29-25)12-22(32-21)24(33)30-13-16-4-5-19(26)20(27)10-16/h3-6,9-12H,7-8,13-14H2,1-2H3,(H,30,33)(H2,28,29,31)
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Vanderbilt University

US Patent


Assay Description
A Time-Resolved Fluorescence Resonance Energy Transfer (TR-FRET) assay that measures the displacement of the 10mer-Thr-FAM probe in response to compo...


US Patent US10807959 (2020)

More data for this
Ligand-Target Pair
WD repeat-containing protein 5 (WDR5)


(Homo sapiens (Human))
BDBM468772
PNG
(US10807959, Example 41)
Show SMILES Cc1cc(cc(C)n1)-c1cc(CNC2=NCCN2)cc(c1)C(=O)NCc1ccc(Cl)c(C)c1
Show InChI InChI=1S/C26H28ClN5O/c1-16-8-19(4-5-24(16)27)14-30-25(33)23-12-20(15-31-26-28-6-7-29-26)11-22(13-23)21-9-17(2)32-18(3)10-21/h4-5,8-13H,6-7,14-15H2,1-3H3,(H,30,33)(H2,28,29,31)
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Vanderbilt University

US Patent


Assay Description
A Time-Resolved Fluorescence Resonance Energy Transfer (TR-FRET) assay that measures the displacement of the 10mer-Thr-FAM probe in response to compo...


US Patent US10807959 (2020)

More data for this
Ligand-Target Pair
WD repeat-containing protein 5 (WDR5)


(Homo sapiens (Human))
BDBM468782
PNG
(US10807959, Example 51)
Show SMILES COc1ccnc(CNC(=O)c2cc(CNC3=NCCN3)cc(c2)-c2cc(C)c(F)cc2C)c1
Show InChI InChI=1S/C26H28FN5O2/c1-16-9-24(27)17(2)8-23(16)19-10-18(14-32-26-29-6-7-30-26)11-20(12-19)25(33)31-15-21-13-22(34-3)4-5-28-21/h4-5,8-13H,6-7,14-15H2,1-3H3,(H,31,33)(H2,29,30,32)
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<0.100n/an/an/an/an/an/an/an/a



Vanderbilt University

US Patent


Assay Description
A Time-Resolved Fluorescence Resonance Energy Transfer (TR-FRET) assay that measures the displacement of the 10mer-Thr-FAM probe in response to compo...


US Patent US10807959 (2020)

More data for this
Ligand-Target Pair
WD repeat-containing protein 5 (WDR5)


(Homo sapiens (Human))
BDBM468777
PNG
(US10807959, Example 46)
Show SMILES COc1ccnc(CNC(=O)c2cc(CNC3=NCCN3)cc(c2)-c2cc(cnc2OC)C(F)(F)F)c1
Show InChI InChI=1S/C25H25F3N6O3/c1-36-20-3-4-29-19(11-20)14-32-22(35)17-8-15(12-34-24-30-5-6-31-24)7-16(9-17)21-10-18(25(26,27)28)13-33-23(21)37-2/h3-4,7-11,13H,5-6,12,14H2,1-2H3,(H,32,35)(H2,30,31,34)
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Vanderbilt University

US Patent


Assay Description
A Time-Resolved Fluorescence Resonance Energy Transfer (TR-FRET) assay that measures the displacement of the 10mer-Thr-FAM probe in response to compo...


US Patent US10807959 (2020)

More data for this
Ligand-Target Pair
WD repeat-containing protein 5 (WDR5)


(Homo sapiens (Human))
BDBM468797
PNG
(US10807959, Example 67)
Show SMILES Cc1cc(CNC(=O)c2cc(CNC3=NCCC3)cc(c2)-c2cccnc2C(F)(F)F)ccc1Cl
Show InChI InChI=1S/C26H24ClF3N4O/c1-16-10-17(6-7-22(16)27)14-34-25(35)20-12-18(15-33-23-5-3-8-31-23)11-19(13-20)21-4-2-9-32-24(21)26(28,29)30/h2,4,6-7,9-13H,3,5,8,14-15H2,1H3,(H,31,33)(H,34,35)
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<0.100n/an/an/an/an/an/an/an/a



Vanderbilt University

US Patent


Assay Description
A Time-Resolved Fluorescence Resonance Energy Transfer (TR-FRET) assay that measures the displacement of the 10mer-Thr-FAM probe in response to compo...


US Patent US10807959 (2020)

More data for this
Ligand-Target Pair
WD repeat-containing protein 5 (WDR5)


(Homo sapiens (Human))
BDBM468816
PNG
(US10807959, Example 86)
Show SMILES COc1ncc(Cl)cc1-c1cc(CNC2=NCCN2)cc(n1)C(=O)NCc1ccc(Cl)c(Cl)c1
Show InChI InChI=1S/C23H21Cl3N6O2/c1-34-22-16(9-15(24)12-30-22)19-7-14(11-31-23-27-4-5-28-23)8-20(32-19)21(33)29-10-13-2-3-17(25)18(26)6-13/h2-3,6-9,12H,4-5,10-11H2,1H3,(H,29,33)(H2,27,28,31)
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<0.100n/an/an/an/an/an/an/an/a



Vanderbilt University

US Patent


Assay Description
A Time-Resolved Fluorescence Resonance Energy Transfer (TR-FRET) assay that measures the displacement of the 10mer-Thr-FAM probe in response to compo...


US Patent US10807959 (2020)

More data for this
Ligand-Target Pair
WD repeat-containing protein 5 (WDR5)


(Homo sapiens (Human))
BDBM468778
PNG
(US10807959, Example 47)
Show SMILES COc1ccnc(CNC(=O)c2cc(CNC3=NCCN3)cc(c2)-c2ccc(F)cc2C(F)(F)F)c1
Show InChI InChI=1S/C25H23F4N5O2/c1-36-20-4-5-30-19(12-20)14-33-23(35)17-9-15(13-34-24-31-6-7-32-24)8-16(10-17)21-3-2-18(26)11-22(21)25(27,28)29/h2-5,8-12H,6-7,13-14H2,1H3,(H,33,35)(H2,31,32,34)
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<0.100n/an/an/an/an/an/an/an/a



Vanderbilt University

US Patent


Assay Description
A Time-Resolved Fluorescence Resonance Energy Transfer (TR-FRET) assay that measures the displacement of the 10mer-Thr-FAM probe in response to compo...


US Patent US10807959 (2020)

More data for this
Ligand-Target Pair
WD repeat-containing protein 5 (WDR5)


(Homo sapiens (Human))
BDBM468781
PNG
(US10807959, Example 50)
Show SMILES COc1ccnc(CNC(=O)c2cc(CNC3=NCCN3)cc(c2)-c2cc(C)c(F)cc2OC)c1
Show InChI InChI=1S/C26H28FN5O3/c1-16-8-22(24(35-3)13-23(16)27)18-9-17(14-32-26-29-6-7-30-26)10-19(11-18)25(33)31-15-20-12-21(34-2)4-5-28-20/h4-5,8-13H,6-7,14-15H2,1-3H3,(H,31,33)(H2,29,30,32)
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<0.100n/an/an/an/an/an/an/an/a



Vanderbilt University

US Patent


Assay Description
A Time-Resolved Fluorescence Resonance Energy Transfer (TR-FRET) assay that measures the displacement of the 10mer-Thr-FAM probe in response to compo...


US Patent US10807959 (2020)

More data for this
Ligand-Target Pair
WD repeat-containing protein 5 (WDR5)


(Homo sapiens (Human))
BDBM468740
PNG
(US10807959, Example 9)
Show SMILES Cc1ccnc(c1)C(NC(=O)c1cc(CNC2=NCCN2)cc(c1)-c1ccc(F)nc1C)C1CC1
Show InChI InChI=1S/C27H29FN6O/c1-16-7-8-29-23(11-16)25(19-3-4-19)34-26(35)21-13-18(15-32-27-30-9-10-31-27)12-20(14-21)22-5-6-24(28)33-17(22)2/h5-8,11-14,19,25H,3-4,9-10,15H2,1-2H3,(H,34,35)(H2,30,31,32)
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<0.100n/an/an/an/an/an/an/an/a



Vanderbilt University

US Patent


Assay Description
A Time-Resolved Fluorescence Resonance Energy Transfer (TR-FRET) assay that measures the displacement of the 10mer-Thr-FAM probe in response to compo...


US Patent US10807959 (2020)

More data for this
Ligand-Target Pair
WD repeat-containing protein 5 (WDR5)


(Homo sapiens (Human))
BDBM468773
PNG
(US10807959, Example 42)
Show SMILES Cc1cnc(F)c(c1)-c1cc(CNC2=NCCN2)cc(c1)C(=O)NCc1ccc(Cl)c(C)c1
Show InChI InChI=1S/C25H25ClFN5O/c1-15-7-21(23(27)30-12-15)19-9-18(14-32-25-28-5-6-29-25)10-20(11-19)24(33)31-13-17-3-4-22(26)16(2)8-17/h3-4,7-12H,5-6,13-14H2,1-2H3,(H,31,33)(H2,28,29,32)
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<0.100n/an/an/an/an/an/an/an/a



Vanderbilt University

US Patent


Assay Description
A Time-Resolved Fluorescence Resonance Energy Transfer (TR-FRET) assay that measures the displacement of the 10mer-Thr-FAM probe in response to compo...


US Patent US10807959 (2020)

More data for this
Ligand-Target Pair
WD repeat-containing protein 5 (WDR5)


(Homo sapiens (Human))
BDBM468743
PNG
(US10807959, Example 12)
Show SMILES Cc1ccncc1-c1cc(CNC2=NCCN2)cc(c1)C(=O)NCc1ccc(Cl)c(Cl)c1
Show InChI InChI=1S/C24H23Cl2N5O/c1-15-4-5-27-14-20(15)18-8-17(13-31-24-28-6-7-29-24)9-19(11-18)23(32)30-12-16-2-3-21(25)22(26)10-16/h2-5,8-11,14H,6-7,12-13H2,1H3,(H,30,32)(H2,28,29,31)
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<0.100n/an/an/an/an/an/an/an/a



Vanderbilt University

US Patent


Assay Description
A Time-Resolved Fluorescence Resonance Energy Transfer (TR-FRET) assay that measures the displacement of the 10mer-Thr-FAM probe in response to compo...


US Patent US10807959 (2020)

More data for this
Ligand-Target Pair
WD repeat-containing protein 5 (WDR5)


(Homo sapiens (Human))
BDBM468942
PNG
(US10807959, Example B116)
Show SMILES COc1ccnc(CNC(=O)c2cc(CNC3=NCCN3)cc(c2)-c2cc(Cl)ccc2OC)c1
Show InChI InChI=1S/C25H26ClN5O3/c1-33-21-5-6-27-20(13-21)15-30-24(32)18-10-16(14-31-25-28-7-8-29-25)9-17(11-18)22-12-19(26)3-4-23(22)34-2/h3-6,9-13H,7-8,14-15H2,1-2H3,(H,30,32)(H2,28,29,31)
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0.106n/an/an/an/an/an/an/an/a



Vanderbilt University

US Patent


Assay Description
FPA Assay protocol adopted from Karatas et al. (J. Med. Chem. 2010, 5179.; J. Amer. Chem. Soc. 2013, 669.): WDR5 (Δ23, residues 24-334), is expr...


US Patent US10807959 (2020)

More data for this
Ligand-Target Pair
WD repeat-containing protein 5 (WDR5)


(Homo sapiens (Human))
BDBM468738
PNG
(US10807959, Example 7)
Show SMILES COc1cc(OC)cc(c1)C(C)NC(=O)c1cc(CNC2=NCCN2)cc(c1)-c1ccc(F)nc1C
Show InChI InChI=1S/C27H30FN5O3/c1-16(19-12-22(35-3)14-23(13-19)36-4)33-26(34)21-10-18(15-31-27-29-7-8-30-27)9-20(11-21)24-5-6-25(28)32-17(24)2/h5-6,9-14,16H,7-8,15H2,1-4H3,(H,33,34)(H2,29,30,31)
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0.110n/an/an/an/an/an/an/an/a



Vanderbilt University

US Patent


Assay Description
A Time-Resolved Fluorescence Resonance Energy Transfer (TR-FRET) assay that measures the displacement of the 10mer-Thr-FAM probe in response to compo...


US Patent US10807959 (2020)

More data for this
Ligand-Target Pair
WD repeat-containing protein 5 (WDR5)


(Homo sapiens (Human))
BDBM468933
PNG
(US10807959, Example B90)
Show SMILES Cc1cc(C)cc(CNC(=O)c2cc(CNC3=NCCN3)cc(c2)-c2ccnc(C)c2)c1
Show InChI InChI=1S/C26H29N5O/c1-17-8-18(2)10-20(9-17)15-30-25(32)24-13-21(16-31-26-28-6-7-29-26)12-23(14-24)22-4-5-27-19(3)11-22/h4-5,8-14H,6-7,15-16H2,1-3H3,(H,30,32)(H2,28,29,31)
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0.115n/an/an/an/an/an/an/an/a



Vanderbilt University

US Patent


Assay Description
FPA Assay protocol adopted from Karatas et al. (J. Med. Chem. 2010, 5179.; J. Amer. Chem. Soc. 2013, 669.): WDR5 (Δ23, residues 24-334), is expr...


US Patent US10807959 (2020)

More data for this
Ligand-Target Pair
WD repeat-containing protein 5 (WDR5)


(Homo sapiens (Human))
BDBM468931
PNG
(US10807959, Example B88)
Show SMILES Cc1cc(CNC(=O)c2cc(CNC3=NCCN3)cc(c2)-c2cnccc2C)ccc1Cl
Show InChI InChI=1S/C25H26ClN5O/c1-16-5-6-27-15-22(16)20-10-19(14-31-25-28-7-8-29-25)11-21(12-20)24(32)30-13-18-3-4-23(26)17(2)9-18/h3-6,9-12,15H,7-8,13-14H2,1-2H3,(H,30,32)(H2,28,29,31)
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0.115n/an/an/an/an/an/an/an/a



Vanderbilt University

US Patent


Assay Description
FPA Assay protocol adopted from Karatas et al. (J. Med. Chem. 2010, 5179.; J. Amer. Chem. Soc. 2013, 669.): WDR5 (Δ23, residues 24-334), is expr...


US Patent US10807959 (2020)

More data for this
Ligand-Target Pair
WD repeat-containing protein 5 (WDR5)


(Homo sapiens (Human))
BDBM468929
PNG
(US10807959, Example B84)
Show SMILES Cc1cc(ccn1)-c1cc(CNC2=NCCN2)cc(c1)C(=O)NCc1ccc(Cl)c(C)c1
Show InChI InChI=1S/C25H26ClN5O/c1-16-9-18(3-4-23(16)26)14-30-24(32)22-12-19(15-31-25-28-7-8-29-25)11-21(13-22)20-5-6-27-17(2)10-20/h3-6,9-13H,7-8,14-15H2,1-2H3,(H,30,32)(H2,28,29,31)
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0.118n/an/an/an/an/an/an/an/a



Vanderbilt University

US Patent


Assay Description
FPA Assay protocol adopted from Karatas et al. (J. Med. Chem. 2010, 5179.; J. Amer. Chem. Soc. 2013, 669.): WDR5 (Δ23, residues 24-334), is expr...


US Patent US10807959 (2020)

More data for this
Ligand-Target Pair
WD repeat-containing protein 5 (WDR5)


(Homo sapiens (Human))
BDBM468818
PNG
(US10807959, Example 88)
Show SMILES CCOc1ncc(C)cc1-c1cc(CNC2=NCCN2)cc(n1)C(=O)NCc1ccc(Cl)c(Cl)c1
Show InChI InChI=1S/C25H26Cl2N6O2/c1-3-35-24-18(8-15(2)12-31-24)21-10-17(14-32-25-28-6-7-29-25)11-22(33-21)23(34)30-13-16-4-5-19(26)20(27)9-16/h4-5,8-12H,3,6-7,13-14H2,1-2H3,(H,30,34)(H2,28,29,32)
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0.120n/an/an/an/an/an/an/an/a



Vanderbilt University

US Patent


Assay Description
A Time-Resolved Fluorescence Resonance Energy Transfer (TR-FRET) assay that measures the displacement of the 10mer-Thr-FAM probe in response to compo...


US Patent US10807959 (2020)

More data for this
Ligand-Target Pair
WD repeat-containing protein 5 (WDR5)


(Homo sapiens (Human))
BDBM468839
PNG
(US10807959, Example 109)
Show SMILES CCn1cc(c(n1)C(F)(F)F)-c1cc(CNC(=N)C2(C)CC2)cc(c1)C(=O)N[C@@H](C1CC1)c1ccc(F)c(C)c1
Show InChI InChI=1S/C30H33F4N5O/c1-4-39-16-23(26(38-39)30(32,33)34)21-12-18(15-36-28(35)29(3)9-10-29)13-22(14-21)27(40)37-25(19-5-6-19)20-7-8-24(31)17(2)11-20/h7-8,11-14,16,19,25H,4-6,9-10,15H2,1-3H3,(H2,35,36)(H,37,40)/t25-/m0/s1
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0.130n/an/an/an/an/an/an/an/a



Vanderbilt University

US Patent


Assay Description
A Time-Resolved Fluorescence Resonance Energy Transfer (TR-FRET) assay that measures the displacement of the 10mer-Thr-FAM probe in response to compo...


US Patent US10807959 (2020)

More data for this
Ligand-Target Pair
WD repeat-containing protein 5 (WDR5)


(Homo sapiens (Human))
BDBM468924
PNG
(US10807959, Example B63)
Show SMILES COc1cc(CNC(=O)c2cc(CNC3=NCCN3)cc(c2)-c2ccc(F)nc2C)cc(OC)c1
Show InChI InChI=1S/C26H28FN5O3/c1-16-23(4-5-24(27)32-16)19-8-17(15-31-26-28-6-7-29-26)9-20(12-19)25(33)30-14-18-10-21(34-2)13-22(11-18)35-3/h4-5,8-13H,6-7,14-15H2,1-3H3,(H,30,33)(H2,28,29,31)
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0.131n/an/an/an/an/an/an/an/a



Vanderbilt University

US Patent


Assay Description
FPA Assay protocol adopted from Karatas et al. (J. Med. Chem. 2010, 5179.; J. Amer. Chem. Soc. 2013, 669.): WDR5 (Δ23, residues 24-334), is expr...


US Patent US10807959 (2020)

More data for this
Ligand-Target Pair
WD repeat-containing protein 5 (WDR5)


(Homo sapiens (Human))
BDBM468949
PNG
(US10807959, Example C22)
Show SMILES Cc1cc(F)ccc1-c1cc(CNC2=NCCC2)cc(n1)C(=O)NCc1ccc(Cl)c(Cl)c1
Show InChI InChI=1S/C25H23Cl2FN4O/c1-15-9-18(28)5-6-19(15)22-11-17(14-30-24-3-2-8-29-24)12-23(32-22)25(33)31-13-16-4-7-20(26)21(27)10-16/h4-7,9-12H,2-3,8,13-14H2,1H3,(H,29,30)(H,31,33)
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0.132n/an/an/an/an/an/an/an/a



Vanderbilt University

US Patent


Assay Description
FPA Assay protocol adopted from Karatas et al. (J. Med. Chem. 2010, 5179.; J. Amer. Chem. Soc. 2013, 669.): WDR5 (Δ23, residues 24-334), is expr...


US Patent US10807959 (2020)

More data for this
Ligand-Target Pair
WD repeat-containing protein 5 (WDR5)


(Homo sapiens (Human))
BDBM468737
PNG
(US10807959, Example 6)
Show SMILES Cc1cc(C)cc(CNC(=O)c2cc(CNC3=NCCN3)cc(c2)-c2ccc(F)nc2C)c1
Show InChI InChI=1S/C26H28FN5O/c1-16-8-17(2)10-19(9-16)14-30-25(33)22-12-20(15-31-26-28-6-7-29-26)11-21(13-22)23-4-5-24(27)32-18(23)3/h4-5,8-13H,6-7,14-15H2,1-3H3,(H,30,33)(H2,28,29,31)
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0.140n/an/an/an/an/an/an/an/a



Vanderbilt University

US Patent


Assay Description
A Time-Resolved Fluorescence Resonance Energy Transfer (TR-FRET) assay that measures the displacement of the 10mer-Thr-FAM probe in response to compo...


US Patent US10807959 (2020)

More data for this
Ligand-Target Pair
WD repeat-containing protein 5 (WDR5)


(Homo sapiens (Human))
BDBM468814
PNG
(US10807959, Example 84)
Show SMILES Cc1cnccc1-c1cc(CNC2=NCCN2)cc(n1)C(=O)NCc1ccc(Cl)c(Cl)c1
Show InChI InChI=1S/C23H22Cl2N6O/c1-14-11-26-5-4-17(14)20-9-16(13-30-23-27-6-7-28-23)10-21(31-20)22(32)29-12-15-2-3-18(24)19(25)8-15/h2-5,8-11H,6-7,12-13H2,1H3,(H,29,32)(H2,27,28,30)
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0.150n/an/an/an/an/an/an/an/a



Vanderbilt University

US Patent


Assay Description
A Time-Resolved Fluorescence Resonance Energy Transfer (TR-FRET) assay that measures the displacement of the 10mer-Thr-FAM probe in response to compo...


US Patent US10807959 (2020)

More data for this
Ligand-Target Pair
WD repeat-containing protein 5 (WDR5)


(Homo sapiens (Human))
BDBM468837
PNG
(US10807959, Example 107)
Show SMILES CCn1cc(c(n1)C(F)(F)F)-c1cc(CNC(=N)CC2CC2)cc(c1)C(=O)N[C@@H](C1CC1)c1ccc(F)c(C)c1
Show InChI InChI=1S/C30H33F4N5O/c1-3-39-16-24(28(38-39)30(32,33)34)22-11-19(15-36-26(35)13-18-4-5-18)12-23(14-22)29(40)37-27(20-6-7-20)21-8-9-25(31)17(2)10-21/h8-12,14,16,18,20,27H,3-7,13,15H2,1-2H3,(H2,35,36)(H,37,40)/t27-/m0/s1
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0.150n/an/an/an/an/an/an/an/a



Vanderbilt University

US Patent


Assay Description
A Time-Resolved Fluorescence Resonance Energy Transfer (TR-FRET) assay that measures the displacement of the 10mer-Thr-FAM probe in response to compo...


US Patent US10807959 (2020)

More data for this
Ligand-Target Pair
WD repeat-containing protein 5 (WDR5)


(Homo sapiens (Human))
BDBM468914
PNG
(US10807959, Example B47)
Show SMILES Cc1cc(CNC(=O)c2ccc(F)c(CNC3=NCCN3)c2)ccc1Cl
Show InChI InChI=1S/C19H20ClFN4O/c1-12-8-13(2-4-16(12)20)10-24-18(26)14-3-5-17(21)15(9-14)11-25-19-22-6-7-23-19/h2-5,8-9H,6-7,10-11H2,1H3,(H,24,26)(H2,22,23,25)
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0.189n/an/an/an/an/an/an/an/a



Vanderbilt University

US Patent


Assay Description
FPA Assay protocol adopted from Karatas et al. (J. Med. Chem. 2010, 5179.; J. Amer. Chem. Soc. 2013, 669.): WDR5 (Δ23, residues 24-334), is expr...


US Patent US10807959 (2020)

More data for this
Ligand-Target Pair
WD repeat-containing protein 5 (WDR5)


(Homo sapiens (Human))
BDBM468930
PNG
(US10807959, Example B87)
Show SMILES Cc1ccncc1-c1cc(CNC2=NCCN2)cc(c1)C(=O)NCc1cc(Cl)cc(Cl)c1
Show InChI InChI=1S/C24H23Cl2N5O/c1-15-2-3-27-14-22(15)18-6-16(13-31-24-28-4-5-29-24)7-19(10-18)23(32)30-12-17-8-20(25)11-21(26)9-17/h2-3,6-11,14H,4-5,12-13H2,1H3,(H,30,32)(H2,28,29,31)
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0.198n/an/an/an/an/an/an/an/a



Vanderbilt University

US Patent


Assay Description
FPA Assay protocol adopted from Karatas et al. (J. Med. Chem. 2010, 5179.; J. Amer. Chem. Soc. 2013, 669.): WDR5 (Δ23, residues 24-334), is expr...


US Patent US10807959 (2020)

More data for this
Ligand-Target Pair
WD repeat-containing protein 5 (WDR5)


(Homo sapiens (Human))
BDBM468756
PNG
(US10807959, Example 25)
Show SMILES Cc1ccnc(c1)C(NC(=O)c1cc(CNC2=NCCN2)cc(c1)-c1cnccc1C)C1CC1
Show InChI InChI=1S/C27H30N6O/c1-17-5-8-29-24(11-17)25(20-3-4-20)33-26(34)22-13-19(15-32-27-30-9-10-31-27)12-21(14-22)23-16-28-7-6-18(23)2/h5-8,11-14,16,20,25H,3-4,9-10,15H2,1-2H3,(H,33,34)(H2,30,31,32)
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0.200n/an/an/an/an/an/an/an/a



Vanderbilt University

US Patent


Assay Description
A Time-Resolved Fluorescence Resonance Energy Transfer (TR-FRET) assay that measures the displacement of the 10mer-Thr-FAM probe in response to compo...


US Patent US10807959 (2020)

More data for this
Ligand-Target Pair
WD repeat-containing protein 5 (WDR5)


(Homo sapiens (Human))
BDBM468792
PNG
(US10807959, Example 62)
Show SMILES COc1cc(CNC(=O)c2cc(CNC3=NCCC3)cc(c2)-c2cc(C)c(F)cc2C)cc(OC)c1
Show InChI InChI=1S/C29H32FN3O3/c1-18-9-27(30)19(2)8-26(18)22-10-20(16-32-28-6-5-7-31-28)11-23(14-22)29(34)33-17-21-12-24(35-3)15-25(13-21)36-4/h8-15H,5-7,16-17H2,1-4H3,(H,31,32)(H,33,34)
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0.210n/an/an/an/an/an/an/an/a



Vanderbilt University

US Patent


Assay Description
A Time-Resolved Fluorescence Resonance Energy Transfer (TR-FRET) assay that measures the displacement of the 10mer-Thr-FAM probe in response to compo...


US Patent US10807959 (2020)

More data for this
Ligand-Target Pair
WD repeat-containing protein 5 (WDR5)


(Homo sapiens (Human))
BDBM468742
PNG
(US10807959, Example 11)
Show SMILES COc1ccnc(CNC(=O)c2cc(CNC3=NCCN3)cc(c2)-c2ccc(F)nc2C)c1
Show InChI InChI=1S/C24H25FN6O2/c1-15-21(3-4-22(25)31-15)17-9-16(13-30-24-27-7-8-28-24)10-18(11-17)23(32)29-14-19-12-20(33-2)5-6-26-19/h3-6,9-12H,7-8,13-14H2,1-2H3,(H,29,32)(H2,27,28,30)
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0.220n/an/an/an/an/an/an/an/a



Vanderbilt University

US Patent


Assay Description
A Time-Resolved Fluorescence Resonance Energy Transfer (TR-FRET) assay that measures the displacement of the 10mer-Thr-FAM probe in response to compo...


US Patent US10807959 (2020)

More data for this
Ligand-Target Pair
WD repeat-containing protein 5 (WDR5)


(Homo sapiens (Human))
BDBM468940
PNG
(US10807959, Example B114)
Show SMILES COc1ccnc(CNC(=O)c2cc(CNC3=NCCN3)cc(c2)-c2ccc(F)cc2C)c1
Show InChI InChI=1S/C25H26FN5O2/c1-16-9-20(26)3-4-23(16)18-10-17(14-31-25-28-7-8-29-25)11-19(12-18)24(32)30-15-21-13-22(33-2)5-6-27-21/h3-6,9-13H,7-8,14-15H2,1-2H3,(H,30,32)(H2,28,29,31)
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0.228n/an/an/an/an/an/an/an/a



Vanderbilt University

US Patent


Assay Description
FPA Assay protocol adopted from Karatas et al. (J. Med. Chem. 2010, 5179.; J. Amer. Chem. Soc. 2013, 669.): WDR5 (Δ23, residues 24-334), is expr...


US Patent US10807959 (2020)

More data for this
Ligand-Target Pair
WD repeat-containing protein 5 (WDR5)


(Homo sapiens (Human))
BDBM468811
PNG
(US10807959, Example 81)
Show SMILES Cc1ccncc1-c1cc(CNC2=NCCN2)cc(n1)C(=O)NCc1ccc(Cl)c(Cl)c1
Show InChI InChI=1S/C23H22Cl2N6O/c1-14-4-5-26-13-17(14)20-9-16(12-30-23-27-6-7-28-23)10-21(31-20)22(32)29-11-15-2-3-18(24)19(25)8-15/h2-5,8-10,13H,6-7,11-12H2,1H3,(H,29,32)(H2,27,28,30)
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0.240n/an/an/an/an/an/an/an/a



Vanderbilt University

US Patent


Assay Description
A Time-Resolved Fluorescence Resonance Energy Transfer (TR-FRET) assay that measures the displacement of the 10mer-Thr-FAM probe in response to compo...


US Patent US10807959 (2020)

More data for this
Ligand-Target Pair
WD repeat-containing protein 5 (WDR5)


(Homo sapiens (Human))
BDBM468769
PNG
(US10807959, Example 38)
Show SMILES Cc1cnc(F)c(c1)-c1cc(CNC2=NCCN2)cc(c1)C(=O)NCc1cc(Cl)ccn1
Show InChI InChI=1S/C23H22ClFN6O/c1-14-6-20(21(25)29-11-14)16-7-15(12-31-23-27-4-5-28-23)8-17(9-16)22(32)30-13-19-10-18(24)2-3-26-19/h2-3,6-11H,4-5,12-13H2,1H3,(H,30,32)(H2,27,28,31)
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0.260n/an/an/an/an/an/an/an/a



Vanderbilt University

US Patent


Assay Description
A Time-Resolved Fluorescence Resonance Energy Transfer (TR-FRET) assay that measures the displacement of the 10mer-Thr-FAM probe in response to compo...


US Patent US10807959 (2020)

More data for this
Ligand-Target Pair
WD repeat-containing protein 5 (WDR5)


(Homo sapiens (Human))
BDBM468753
PNG
(US10807959, Example 22)
Show SMILES Cc1cc(ccn1)-c1cc(CNC2=NCCN2)cc(c1)C(=O)NCc1cc(Cl)ccn1
Show InChI InChI=1S/C23H23ClN6O/c1-15-8-17(2-4-25-15)18-9-16(13-30-23-27-6-7-28-23)10-19(11-18)22(31)29-14-21-12-20(24)3-5-26-21/h2-5,8-12H,6-7,13-14H2,1H3,(H,29,31)(H2,27,28,30)
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0.280n/an/an/an/an/an/an/an/a



Vanderbilt University

US Patent


Assay Description
A Time-Resolved Fluorescence Resonance Energy Transfer (TR-FRET) assay that measures the displacement of the 10mer-Thr-FAM probe in response to compo...


US Patent US10807959 (2020)

More data for this
Ligand-Target Pair
WD repeat-containing protein 5 (WDR5)


(Homo sapiens (Human))
BDBM468858
PNG
(US10807959, Example 164)
Show SMILES Cc1nccn1Cc1cc(nc(c1)-c1ccc(F)nc1C)C(=O)NCc1ccc(Cl)c(Cl)c1
Show InChI InChI=1S/C24H20Cl2FN5O/c1-14-18(4-6-23(27)30-14)21-10-17(13-32-8-7-28-15(32)2)11-22(31-21)24(33)29-12-16-3-5-19(25)20(26)9-16/h3-11H,12-13H2,1-2H3,(H,29,33)
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0.280n/an/an/an/an/an/an/an/a



Vanderbilt University

US Patent


Assay Description
A Time-Resolved Fluorescence Resonance Energy Transfer (TR-FRET) assay that measures the displacement of the 10mer-Thr-FAM probe in response to compo...


US Patent US10807959 (2020)

More data for this
Ligand-Target Pair
WD repeat-containing protein 5 (WDR5)


(Homo sapiens (Human))
BDBM468780
PNG
(US10807959, Example 49)
Show SMILES COc1ccnc(CNC(=O)c2cc(CNC3=NCCN3)cc(c2)-c2ccc(F)cc2OC)c1
Show InChI InChI=1S/C25H26FN5O3/c1-33-21-5-6-27-20(13-21)15-30-24(32)18-10-16(14-31-25-28-7-8-29-25)9-17(11-18)22-4-3-19(26)12-23(22)34-2/h3-6,9-13H,7-8,14-15H2,1-2H3,(H,30,32)(H2,28,29,31)
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0.300n/an/an/an/an/an/an/an/a



Vanderbilt University

US Patent


Assay Description
A Time-Resolved Fluorescence Resonance Energy Transfer (TR-FRET) assay that measures the displacement of the 10mer-Thr-FAM probe in response to compo...


US Patent US10807959 (2020)

More data for this
Ligand-Target Pair
WD repeat-containing protein 5 (WDR5)


(Homo sapiens (Human))
BDBM468798
PNG
(US10807959, Example 68)
Show SMILES Cc1cc(CNC(=O)c2cc(CNC3=NCCC3)cc(c2)-c2ccc(F)cc2C(F)(F)F)ccc1Cl
Show InChI InChI=1S/C27H24ClF4N3O/c1-16-9-17(4-7-24(16)28)14-35-26(36)20-11-18(15-34-25-3-2-8-33-25)10-19(12-20)22-6-5-21(29)13-23(22)27(30,31)32/h4-7,9-13H,2-3,8,14-15H2,1H3,(H,33,34)(H,35,36)
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0.300n/an/an/an/an/an/an/an/a



Vanderbilt University

US Patent


Assay Description
A Time-Resolved Fluorescence Resonance Energy Transfer (TR-FRET) assay that measures the displacement of the 10mer-Thr-FAM probe in response to compo...


US Patent US10807959 (2020)

More data for this
Ligand-Target Pair
WD repeat-containing protein 5 (WDR5)


(Homo sapiens (Human))
BDBM468784
PNG
(US10807959, Example 54)
Show SMILES CC(NC(=O)c1cc(CNC2=NCCC2)cc(c1)-c1ccc(F)nc1C)c1cc(C)c(Cl)cn1
Show InChI InChI=1S/C26H27ClFN5O/c1-15-9-23(30-14-22(15)27)17(3)33-26(34)20-11-18(13-31-25-5-4-8-29-25)10-19(12-20)21-6-7-24(28)32-16(21)2/h6-7,9-12,14,17H,4-5,8,13H2,1-3H3,(H,29,31)(H,33,34)
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0.310n/an/an/an/an/an/an/an/a



Vanderbilt University

US Patent


Assay Description
A Time-Resolved Fluorescence Resonance Energy Transfer (TR-FRET) assay that measures the displacement of the 10mer-Thr-FAM probe in response to compo...


US Patent US10807959 (2020)

More data for this
Ligand-Target Pair
WD repeat-containing protein 5 (WDR5)


(Homo sapiens (Human))
BDBM468813
PNG
(US10807959, Example 83)
Show SMILES COc1ncc(C)cc1-c1cc(CNC2=NCCN2)cc(n1)C(=O)NCc1ccc(Cl)c(Cl)c1
Show InChI InChI=1S/C24H24Cl2N6O2/c1-14-7-17(23(34-2)30-11-14)20-9-16(13-31-24-27-5-6-28-24)10-21(32-20)22(33)29-12-15-3-4-18(25)19(26)8-15/h3-4,7-11H,5-6,12-13H2,1-2H3,(H,29,33)(H2,27,28,31)
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0.310n/an/an/an/an/an/an/an/a



Vanderbilt University

US Patent


Assay Description
A Time-Resolved Fluorescence Resonance Energy Transfer (TR-FRET) assay that measures the displacement of the 10mer-Thr-FAM probe in response to compo...


US Patent US10807959 (2020)

More data for this
Ligand-Target Pair
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* indicates data uncertainty>20%