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Patent code US10828300

Compile Data Set for Download or QSAR

Found 248 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Tyrosine-protein kinase BTK


(Homo sapiens (Human))
BDBM397143
PNG
(US10596172, Compound I-8 | US10828300, Compound I-...)
Show SMILES Cc1cccc(Nc2nc(Nc3cccc(NC(=O)C=C)c3)ncc2C)c1
Show InChI InChI=1S/C21H21N5O/c1-4-19(27)23-17-9-6-10-18(12-17)25-21-22-13-15(3)20(26-21)24-16-8-5-7-14(2)11-16/h4-13H,1H2,2-3H3,(H,23,27)(H2,22,24,25,26)
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n/an/a<10n/an/an/an/an/an/a



Celgene CAR LLC

US Patent


Assay Description
Briefly, 10× stocks of EGFR-WT (PV3872) from Invitrogen and EGFR-T790M/L858R (40350) from BPS Bioscience, San Diego, Calif., 1.13×ATP (AS001A) and ap...


US Patent US10828300 (2020)

More data for this
Ligand-Target Pair
Tyrosine-protein kinase BTK


(Homo sapiens (Human))
BDBM397145
PNG
(US10596172, Compound I-7 | US10828300, Compound IR...)
Show SMILES Cc1cnc(Nc2ccccc2)nc1Nc1cccc(NC(=O)C=C)c1
Show InChI InChI=1S/C20H19N5O/c1-3-18(26)22-16-10-7-11-17(12-16)23-19-14(2)13-21-20(25-19)24-15-8-5-4-6-9-15/h3-13H,1H2,2H3,(H,22,26)(H2,21,23,24,25)
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n/an/a<10n/an/an/an/an/an/a



Celgene CAR LLC

US Patent


Assay Description
Briefly, 10× stocks of EGFR-WT (PV3872) from Invitrogen and EGFR-T790M/L858R (40350) from BPS Bioscience, San Diego, Calif., 1.13×ATP (AS001A) and ap...


US Patent US10828300 (2020)

More data for this
Ligand-Target Pair
Tyrosine-protein kinase BTK


(Homo sapiens (Human))
BDBM397152
PNG
(US10596172, Compound I-40 | US10828300, Compound I...)
Show SMILES Cc1cnc(Nc2cccc(c2)S(N)(=O)=O)nc1Nc1ccc2CN(CCc2c1)C(=O)C=C
Show InChI InChI=1S/C23H24N6O3S/c1-3-21(30)29-10-9-16-11-19(8-7-17(16)14-29)26-22-15(2)13-25-23(28-22)27-18-5-4-6-20(12-18)33(24,31)32/h3-8,11-13H,1,9-10,14H2,2H3,(H2,24,31,32)(H2,25,26,27,28)
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Celgene CAR LLC

US Patent


Assay Description
Briefly, 10× stocks of EGFR-WT (PV3872) from Invitrogen and EGFR-T790M/L858R (40350) from BPS Bioscience, San Diego, Calif., 1.13×ATP (AS001A) and ap...


US Patent US10828300 (2020)

More data for this
Ligand-Target Pair
Tyrosine-protein kinase BTK


(Homo sapiens (Human))
BDBM397160
PNG
(US10596172, Compound I-73 | US10828300, Compound I...)
Show SMILES CC(C)(O)COc1ccc(Nc2ncc(F)c(Nc3cccc(NC(=O)C=C)c3)n2)cc1
Show InChI InChI=1S/C23H24FN5O3/c1-4-20(30)26-16-6-5-7-17(12-16)27-21-19(24)13-25-22(29-21)28-15-8-10-18(11-9-15)32-14-23(2,3)31/h4-13,31H,1,14H2,2-3H3,(H,26,30)(H2,25,27,28,29)
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n/an/a<10n/an/an/an/an/an/a



Celgene CAR LLC

US Patent


Assay Description
Briefly, 10× stocks of EGFR-WT (PV3872) from Invitrogen and EGFR-T790M/L858R (40350) from BPS Bioscience, San Diego, Calif., 1.13×ATP (AS001A) and ap...


US Patent US10828300 (2020)

More data for this
Ligand-Target Pair
Tyrosine-protein kinase BTK


(Homo sapiens (Human))
BDBM397303
PNG
(US10596172, Compound I-84 | US10828300, Compound I...)
Show SMILES OCCN1CCN(CC1)c1cccc(Nc2ncc(F)c(Oc3cccc(NC(=O)C=C)c3)n2)c1
Show InChI InChI=1S/C25H27FN6O3/c1-2-23(34)28-19-6-4-8-21(16-19)35-24-22(26)17-27-25(30-24)29-18-5-3-7-20(15-18)32-11-9-31(10-12-32)13-14-33/h2-8,15-17,33H,1,9-14H2,(H,28,34)(H,27,29,30)
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Celgene CAR LLC

US Patent


Assay Description
Briefly, 10× stocks of EGFR-WT (PV3872) from Invitrogen and EGFR-T790M/L858R (40350) from BPS Bioscience, San Diego, Calif., 1.13×ATP (AS001A) and ap...


US Patent US10828300 (2020)

More data for this
Ligand-Target Pair
Tyrosine-protein kinase BTK


(Homo sapiens (Human))
BDBM397310
PNG
(US10596172, Compound I-99 | US10828300, Compound I...)
Show SMILES Cc1cccc(Nc2nc(Nc3cccc(NC(=O)\C=C\CN4CC[C@H](O)C4)c3)ncc2F)c1
Show InChI InChI=1S/C25H27FN6O2/c1-17-5-2-6-18(13-17)29-24-22(26)15-27-25(31-24)30-20-8-3-7-19(14-20)28-23(34)9-4-11-32-12-10-21(33)16-32/h2-9,13-15,21,33H,10-12,16H2,1H3,(H,28,34)(H2,27,29,30,31)/b9-4+/t21-/m0/s1
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Celgene CAR LLC

US Patent


Assay Description
Briefly, 10× stocks of EGFR-WT (PV3872) from Invitrogen and EGFR-T790M/L858R (40350) from BPS Bioscience, San Diego, Calif., 1.13×ATP (AS001A) and ap...


US Patent US10828300 (2020)

More data for this
Ligand-Target Pair
Tyrosine-protein kinase BTK


(Homo sapiens (Human))
BDBM397175
PNG
(US10596172, Compound I-103 | US10828300, Compound ...)
Show SMILES COCCOc1ccc(Nc2ncc(F)c(Nc3cccc(NC(=O)C=C)c3)n2)cn1
Show InChI InChI=1S/C21H21FN6O3/c1-3-18(29)25-14-5-4-6-15(11-14)26-20-17(22)13-24-21(28-20)27-16-7-8-19(23-12-16)31-10-9-30-2/h3-8,11-13H,1,9-10H2,2H3,(H,25,29)(H2,24,26,27,28)
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n/an/a<10n/an/an/an/an/an/a



Celgene CAR LLC

US Patent


Assay Description
Briefly, 10× stocks of EGFR-WT (PV3872) from Invitrogen and EGFR-T790M/L858R (40350) from BPS Bioscience, San Diego, Calif., 1.13×ATP (AS001A) and ap...


US Patent US10828300 (2020)

More data for this
Ligand-Target Pair
Tyrosine-protein kinase BTK


(Homo sapiens (Human))
BDBM397176
PNG
(US10596172, Compound I-105 | US10828300, Compound ...)
Show SMILES OCCOc1cccc(Nc2ncc(F)c(Nc3cccc(NC(=O)C=C)c3)n2)c1
Show InChI InChI=1S/C21H20FN5O3/c1-2-19(29)24-14-5-3-6-15(11-14)25-20-18(22)13-23-21(27-20)26-16-7-4-8-17(12-16)30-10-9-28/h2-8,11-13,28H,1,9-10H2,(H,24,29)(H2,23,25,26,27)
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n/an/a<10n/an/an/an/an/an/a



Celgene CAR LLC

US Patent


Assay Description
Briefly, 10× stocks of EGFR-WT (PV3872) from Invitrogen and EGFR-T790M/L858R (40350) from BPS Bioscience, San Diego, Calif., 1.13×ATP (AS001A) and ap...


US Patent US10828300 (2020)

More data for this
Ligand-Target Pair
Tyrosine-protein kinase BTK


(Homo sapiens (Human))
BDBM397318
PNG
(US10596172, Compound I-112 | US10828300, Compound ...)
Show SMILES CC(=O)N1CCOc2ccc(Nc3ncc(F)c(Nc4cccc(NC(=O)C=C)c4)n3)cc12
Show InChI InChI=1S/C23H21FN6O3/c1-3-21(32)26-15-5-4-6-16(11-15)27-22-18(24)13-25-23(29-22)28-17-7-8-20-19(12-17)30(14(2)31)9-10-33-20/h3-8,11-13H,1,9-10H2,2H3,(H,26,32)(H2,25,27,28,29)
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n/an/a<10n/an/an/an/an/an/a



Celgene CAR LLC

US Patent


Assay Description
Briefly, 10× stocks of EGFR-WT (PV3872) from Invitrogen and EGFR-T790M/L858R (40350) from BPS Bioscience, San Diego, Calif., 1.13×ATP (AS001A) and ap...


US Patent US10828300 (2020)

More data for this
Ligand-Target Pair
Tyrosine-protein kinase BTK


(Homo sapiens (Human))
BDBM397189
PNG
(US10596172, Compound I-125 | US10828300, Compound ...)
Show SMILES COc1ccc(Nc2ncc(F)c(Nc3cccc(NC(=O)\C=C\CN(C)C)c3)n2)cn1
Show InChI InChI=1S/C22H24FN7O2/c1-30(2)11-5-8-19(31)26-15-6-4-7-16(12-15)27-21-18(23)14-25-22(29-21)28-17-9-10-20(32-3)24-13-17/h4-10,12-14H,11H2,1-3H3,(H,26,31)(H2,25,27,28,29)/b8-5+
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n/an/a<10n/an/an/an/an/an/a



Celgene CAR LLC

US Patent


Assay Description
Briefly, 10× stocks of EGFR-WT (PV3872) from Invitrogen and EGFR-T790M/L858R (40350) from BPS Bioscience, San Diego, Calif., 1.13×ATP (AS001A) and ap...


US Patent US10828300 (2020)

More data for this
Ligand-Target Pair
Tyrosine-protein kinase BTK


(Homo sapiens (Human))
BDBM397327
PNG
(US10596172, Compound I-132 | US10828300, Compound ...)
Show SMILES COc1cccc(Nc2ncc(c(Nc3ccc4CN(Cc4c3)C(=O)C=C)n2)C(F)(F)F)c1
Show InChI InChI=1S/C23H20F3N5O2/c1-3-20(32)31-12-14-7-8-17(9-15(14)13-31)28-21-19(23(24,25)26)11-27-22(30-21)29-16-5-4-6-18(10-16)33-2/h3-11H,1,12-13H2,2H3,(H2,27,28,29,30)
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n/an/a<10n/an/an/an/an/an/a



Celgene CAR LLC

US Patent


Assay Description
Briefly, 10× stocks of EGFR-WT (PV3872) from Invitrogen and EGFR-T790M/L858R (40350) from BPS Bioscience, San Diego, Calif., 1.13×ATP (AS001A) and ap...


US Patent US10828300 (2020)

More data for this
Ligand-Target Pair
Tyrosine-protein kinase BTK


(Homo sapiens (Human))
BDBM397196
PNG
(US10596172, Compound I-135 | US10828300, Compound ...)
Show SMILES Fc1cnc(Nc2cccc(OCCN3CCOCC3)c2)nc1N[C@@H]1CCCN(C1)C(=O)C=C
Show InChI InChI=1S/C24H31FN6O3/c1-2-22(32)31-8-4-6-19(17-31)27-23-21(25)16-26-24(29-23)28-18-5-3-7-20(15-18)34-14-11-30-9-12-33-13-10-30/h2-3,5,7,15-16,19H,1,4,6,8-14,17H2,(H2,26,27,28,29)/t19-/m1/s1
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n/an/a<10n/an/an/an/an/an/a



Celgene CAR LLC

US Patent


Assay Description
Briefly, 10× stocks of EGFR-WT (PV3872) from Invitrogen and EGFR-T790M/L858R (40350) from BPS Bioscience, San Diego, Calif., 1.13×ATP (AS001A) and ap...


US Patent US10828300 (2020)

More data for this
Ligand-Target Pair
Tyrosine-protein kinase BTK


(Homo sapiens (Human))
BDBM397330
PNG
(US10596172, Compound I-141 | US10828300, Compound ...)
Show SMILES COCCOc1ccc(Nc2ncc(F)c(Nc3ccc4OCCN(C(=O)C=C)c4c3)n2)cc1
Show InChI InChI=1S/C24H24FN5O4/c1-3-22(31)30-10-11-34-21-9-6-17(14-20(21)30)27-23-19(25)15-26-24(29-23)28-16-4-7-18(8-5-16)33-13-12-32-2/h3-9,14-15H,1,10-13H2,2H3,(H2,26,27,28,29)
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n/an/a<10n/an/an/an/an/an/a



Celgene CAR LLC

US Patent


Assay Description
Briefly, 10× stocks of EGFR-WT (PV3872) from Invitrogen and EGFR-T790M/L858R (40350) from BPS Bioscience, San Diego, Calif., 1.13×ATP (AS001A) and ap...


US Patent US10828300 (2020)

More data for this
Ligand-Target Pair
Tyrosine-protein kinase BTK


(Homo sapiens (Human))
BDBM397334
PNG
(US10596172, Compound I-161 | US10828300, Compound ...)
Show SMILES OC(C(=C)C#N)c1ccc(Nc2nc(Nc3ccccc3)ncc2F)cc1
Show InChI InChI=1S/C20H16FN5O/c1-13(11-22)18(27)14-7-9-16(10-8-14)24-19-17(21)12-23-20(26-19)25-15-5-3-2-4-6-15/h2-10,12,18,27H,1H2,(H2,23,24,25,26)
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n/an/a<10n/an/an/an/an/an/a



Celgene CAR LLC

US Patent


Assay Description
Briefly, 10× stocks of EGFR-WT (PV3872) from Invitrogen and EGFR-T790M/L858R (40350) from BPS Bioscience, San Diego, Calif., 1.13×ATP (AS001A) and ap...


US Patent US10828300 (2020)

More data for this
Ligand-Target Pair
Tyrosine-protein kinase BTK


(Homo sapiens (Human))
BDBM397238
PNG
(US10596172, Compound I-190 | US10828300, Compound ...)
Show SMILES COc1cccc(Nc2ncc(F)c(O[C@@H]3CCCN(C3)C(=O)C=C)n2)c1
Show InChI InChI=1S/C19H21FN4O3/c1-3-17(25)24-9-5-8-15(12-24)27-18-16(20)11-21-19(23-18)22-13-6-4-7-14(10-13)26-2/h3-4,6-7,10-11,15H,1,5,8-9,12H2,2H3,(H,21,22,23)/t15-/m1/s1
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n/an/a<10n/an/an/an/an/an/a



Celgene CAR LLC

US Patent


Assay Description
Briefly, 10× stocks of EGFR-WT (PV3872) from Invitrogen and EGFR-T790M/L858R (40350) from BPS Bioscience, San Diego, Calif., 1.13×ATP (AS001A) and ap...


US Patent US10828300 (2020)

More data for this
Ligand-Target Pair
Tyrosine-protein kinase BTK


(Homo sapiens (Human))
BDBM397244
PNG
(US10828300, Compound I-200 | US9987276, Compound I...)
Show SMILES COc1cccc(Nc2ncc(C(=O)Nc3ccccc3)c(Oc3cccc(NC(=O)C=C)c3)n2)c1
Show InChI InChI=1S/C27H23N5O4/c1-3-24(33)29-19-11-8-14-22(16-19)36-26-23(25(34)30-18-9-5-4-6-10-18)17-28-27(32-26)31-20-12-7-13-21(15-20)35-2/h3-17H,1H2,2H3,(H,29,33)(H,30,34)(H,28,31,32)
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Celgene CAR LLC

US Patent


Assay Description
Briefly, 10× stocks of EGFR-WT (PV3872) from Invitrogen and EGFR-T790M/L858R (40350) from BPS Bioscience, San Diego, Calif., 1.13×ATP (AS001A) and ap...


US Patent US10828300 (2020)

More data for this
Ligand-Target Pair
Tyrosine-protein kinase BTK


(Homo sapiens (Human))
BDBM397246
PNG
(US10596172, Compound I-202 | US10828300, Compound ...)
Show SMILES COc1ccc(Nc2ncc(F)c(N[C@@H]3CCCN(C3)C(=O)C=C)n2)cn1
Show InChI InChI=1S/C18H21FN6O2/c1-3-16(26)25-8-4-5-13(11-25)22-17-14(19)10-21-18(24-17)23-12-6-7-15(27-2)20-9-12/h3,6-7,9-10,13H,1,4-5,8,11H2,2H3,(H2,21,22,23,24)/t13-/m1/s1
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n/an/a<10n/an/an/an/an/an/a



Celgene CAR LLC

US Patent


Assay Description
Briefly, 10× stocks of EGFR-WT (PV3872) from Invitrogen and EGFR-T790M/L858R (40350) from BPS Bioscience, San Diego, Calif., 1.13×ATP (AS001A) and ap...


US Patent US10828300 (2020)

More data for this
Ligand-Target Pair
Tyrosine-protein kinase BTK


(Homo sapiens (Human))
BDBM397254
PNG
(US10596172, Compound I-218 | US10828300, Compound ...)
Show SMILES COc1ccc(Nc2ncc(c(Nc3cccc(NC(=O)C=C)c3)n2)C(F)(F)F)cn1
Show InChI InChI=1S/C20H17F3N6O2/c1-3-16(30)26-12-5-4-6-13(9-12)27-18-15(20(21,22)23)11-25-19(29-18)28-14-7-8-17(31-2)24-10-14/h3-11H,1H2,2H3,(H,26,30)(H2,25,27,28,29)
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n/an/a<10n/an/an/an/an/an/a



Celgene CAR LLC

US Patent


Assay Description
Briefly, 10× stocks of EGFR-WT (PV3872) from Invitrogen and EGFR-T790M/L858R (40350) from BPS Bioscience, San Diego, Calif., 1.13×ATP (AS001A) and ap...


US Patent US10828300 (2020)

More data for this
Ligand-Target Pair
Tyrosine-protein kinase BTK


(Homo sapiens (Human))
BDBM397257
PNG
(US10596172, Compound I-227 | US10828300, Compound ...)
Show SMILES COc1cccc(Nc2ncc(c(Nc3ccc(Cl)c(NC(=O)C=C)c3)n2)C(F)(F)F)c1
Show InChI InChI=1S/C21H17ClF3N5O2/c1-3-18(31)29-17-10-13(7-8-16(17)22)27-19-15(21(23,24)25)11-26-20(30-19)28-12-5-4-6-14(9-12)32-2/h3-11H,1H2,2H3,(H,29,31)(H2,26,27,28,30)
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n/an/a<10n/an/an/an/an/an/a



Celgene CAR LLC

US Patent


Assay Description
Briefly, 10× stocks of EGFR-WT (PV3872) from Invitrogen and EGFR-T790M/L858R (40350) from BPS Bioscience, San Diego, Calif., 1.13×ATP (AS001A) and ap...


US Patent US10828300 (2020)

More data for this
Ligand-Target Pair
Tyrosine-protein kinase BTK


(Homo sapiens (Human))
BDBM397270
PNG
(US10596172, Compound I-315 | US10828300, Compound ...)
Show SMILES CC(C)(O)COc1ccc(Nc2ncc(F)c(Nc3cccc(NC(=O)C=C)c3)n2)cc1F
Show InChI InChI=1S/C23H23F2N5O3/c1-4-20(31)27-14-6-5-7-15(10-14)28-21-18(25)12-26-22(30-21)29-16-8-9-19(17(24)11-16)33-13-23(2,3)32/h4-12,32H,1,13H2,2-3H3,(H,27,31)(H2,26,28,29,30)
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Celgene CAR LLC

US Patent


Assay Description
Briefly, 10× stocks of EGFR-WT (PV3872) from Invitrogen and EGFR-T790M/L858R (40350) from BPS Bioscience, San Diego, Calif., 1.13×ATP (AS001A) and ap...


US Patent US10828300 (2020)

More data for this
Ligand-Target Pair
Tyrosine-protein kinase BTK


(Homo sapiens (Human))
BDBM397386
PNG
(US10596172, Compound I-348 | US10828300, Compound ...)
Show SMILES Fc1cnc(Nc2ccc(O[C@@H]3CCOC3)cc2)nc1N[C@@H]1CCCN(C1)C(=O)C=C
Show InChI InChI=1S/C22H26FN5O3/c1-2-20(29)28-10-3-4-16(13-28)25-21-19(23)12-24-22(27-21)26-15-5-7-17(8-6-15)31-18-9-11-30-14-18/h2,5-8,12,16,18H,1,3-4,9-11,13-14H2,(H2,24,25,26,27)/t16-,18-/m1/s1
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Celgene CAR LLC

US Patent


Assay Description
Briefly, 10× stocks of EGFR-WT (PV3872) from Invitrogen and EGFR-T790M/L858R (40350) from BPS Bioscience, San Diego, Calif., 1.13×ATP (AS001A) and ap...


US Patent US10828300 (2020)

More data for this
Ligand-Target Pair
Tyrosine-protein kinase BTK


(Homo sapiens (Human))
BDBM397142
PNG
(US10596172, Compound I-1 | US10828300, Compound I-...)
Show SMILES Cc1cccc(Nc2ccnc(Nc3cccc(NC(=O)C=C)c3)n2)c1
Show InChI InChI=1S/C20H19N5O/c1-3-19(26)23-16-8-5-9-17(13-16)24-20-21-11-10-18(25-20)22-15-7-4-6-14(2)12-15/h3-13H,1H2,2H3,(H,23,26)(H2,21,22,24,25)
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Celgene CAR LLC

US Patent


Assay Description
Briefly, 10× stocks of EGFR-WT (PV3872) from Invitrogen and EGFR-T790M/L858R (40350) from BPS Bioscience, San Diego, Calif., 1.13×ATP (AS001A) and ap...


US Patent US10828300 (2020)

More data for this
Ligand-Target Pair
Tyrosine-protein kinase BTK


(Homo sapiens (Human))
BDBM397147
PNG
(US10596172, Compound I-28 | US10828300, Compound I...)
Show SMILES Fc1cnc(Nc2ccccc2)nc1Nc1cccc(NC(=O)C=C)c1
Show InChI InChI=1S/C19H16FN5O/c1-2-17(26)22-14-9-6-10-15(11-14)23-18-16(20)12-21-19(25-18)24-13-7-4-3-5-8-13/h2-12H,1H2,(H,22,26)(H2,21,23,24,25)
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Celgene CAR LLC

US Patent


Assay Description
Briefly, 10× stocks of EGFR-WT (PV3872) from Invitrogen and EGFR-T790M/L858R (40350) from BPS Bioscience, San Diego, Calif., 1.13×ATP (AS001A) and ap...


US Patent US10828300 (2020)

More data for this
Ligand-Target Pair
Tyrosine-protein kinase BTK


(Homo sapiens (Human))
BDBM397150
PNG
(US10596172, Compound I-38 | US10828300, Compound I...)
Show SMILES CN(C)C\C=C\C(=O)Nc1cccc(Nc2nc(Nc3ccccc3)ncc2C)c1
Show InChI InChI=1S/C23H26N6O/c1-17-16-24-23(27-18-9-5-4-6-10-18)28-22(17)26-20-12-7-11-19(15-20)25-21(30)13-8-14-29(2)3/h4-13,15-16H,14H2,1-3H3,(H,25,30)(H2,24,26,27,28)/b13-8+
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Celgene CAR LLC

US Patent


Assay Description
Briefly, 10× stocks of EGFR-WT (PV3872) from Invitrogen and EGFR-T790M/L858R (40350) from BPS Bioscience, San Diego, Calif., 1.13×ATP (AS001A) and ap...


US Patent US10828300 (2020)

More data for this
Ligand-Target Pair
Tyrosine-protein kinase BTK


(Homo sapiens (Human))
BDBM397151
PNG
(US10596172, Compound I-39 | US10828300, Compound I...)
Show SMILES Cc1cnc(Nc2ccccc2)nc1Nc1ccc(NC(=O)C=C)cc1
Show InChI InChI=1S/C20H19N5O/c1-3-18(26)22-16-9-11-17(12-10-16)23-19-14(2)13-21-20(25-19)24-15-7-5-4-6-8-15/h3-13H,1H2,2H3,(H,22,26)(H2,21,23,24,25)
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Celgene CAR LLC

US Patent


Assay Description
Briefly, 10× stocks of EGFR-WT (PV3872) from Invitrogen and EGFR-T790M/L858R (40350) from BPS Bioscience, San Diego, Calif., 1.13×ATP (AS001A) and ap...


US Patent US10828300 (2020)

More data for this
Ligand-Target Pair
Tyrosine-protein kinase BTK


(Homo sapiens (Human))
BDBM397179
PNG
(US10596172, Compound I-110 | US10828300, Compound ...)
Show SMILES Fc1cnc(Nc2cccc(OCC(=O)N3CCOCC3)c2)nc1Nc1cccc(NC(=O)C=C)c1
Show InChI InChI=1S/C25H25FN6O4/c1-2-22(33)28-17-5-3-6-18(13-17)29-24-21(26)15-27-25(31-24)30-19-7-4-8-20(14-19)36-16-23(34)32-9-11-35-12-10-32/h2-8,13-15H,1,9-12,16H2,(H,28,33)(H2,27,29,30,31)
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Celgene CAR LLC

US Patent


Assay Description
Briefly, 10× stocks of EGFR-WT (PV3872) from Invitrogen and EGFR-T790M/L858R (40350) from BPS Bioscience, San Diego, Calif., 1.13×ATP (AS001A) and ap...


US Patent US10828300 (2020)

More data for this
Ligand-Target Pair
Tyrosine-protein kinase BTK


(Homo sapiens (Human))
BDBM397200
PNG
(US10596172, Compound I-142 | US10828300, Compound ...)
Show SMILES CN(C(=O)C(F)(F)F)c1ccc(Nc2ncc(C(C)=O)c(Nc3ccc4OCCN(C(=O)C=C)c4c3)n2)cn1
Show InChI InChI=1S/C25H22F3N7O4/c1-4-21(37)35-9-10-39-19-7-5-15(11-18(19)35)31-22-17(14(2)36)13-30-24(33-22)32-16-6-8-20(29-12-16)34(3)23(38)25(26,27)28/h4-8,11-13H,1,9-10H2,2-3H3,(H2,30,31,32,33)
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Celgene CAR LLC

US Patent


Assay Description
Briefly, 10× stocks of EGFR-WT (PV3872) from Invitrogen and EGFR-T790M/L858R (40350) from BPS Bioscience, San Diego, Calif., 1.13×ATP (AS001A) and ap...


US Patent US10828300 (2020)

More data for this
Ligand-Target Pair
Tyrosine-protein kinase BTK


(Homo sapiens (Human))
BDBM437815
PNG
(US10596172, Compound I-149 | US10828300, Compound ...)
Show SMILES Fc1cnc(Nc2ccc3OCCN(C(=O)C=C)c3c2)nc1Nc1cccc(Cl)c1
Show InChI InChI=1S/C21H17ClFN5O2/c1-2-19(29)28-8-9-30-18-7-6-15(11-17(18)28)26-21-24-12-16(23)20(27-21)25-14-5-3-4-13(22)10-14/h2-7,10-12H,1,8-9H2,(H2,24,25,26,27)
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Celgene CAR LLC

US Patent


Assay Description
Briefly, 10× stocks of EGFR-WT (PV3872) from Invitrogen and EGFR-T790M/L858R (40350) from BPS Bioscience, San Diego, Calif., 1.13×ATP (AS001A) and ap...


US Patent US10828300 (2020)

More data for this
Ligand-Target Pair
Tyrosine-protein kinase BTK


(Homo sapiens (Human))
BDBM397219
PNG
(US10596172, Compound I-165 | US10828300, Compound ...)
Show SMILES COc1ccc(Nc2ncc(F)c(Nc3ccc4CN(Cc4c3)C(=O)C=C)n2)cn1
Show InChI InChI=1S/C21H19FN6O2/c1-3-19(29)28-11-13-4-5-15(8-14(13)12-28)25-20-17(22)10-24-21(27-20)26-16-6-7-18(30-2)23-9-16/h3-10H,1,11-12H2,2H3,(H2,24,25,26,27)
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Celgene CAR LLC

US Patent


Assay Description
Briefly, 10× stocks of EGFR-WT (PV3872) from Invitrogen and EGFR-T790M/L858R (40350) from BPS Bioscience, San Diego, Calif., 1.13×ATP (AS001A) and ap...


US Patent US10828300 (2020)

More data for this
Ligand-Target Pair
Tyrosine-protein kinase BTK


(Homo sapiens (Human))
BDBM471867
PNG
(US10828300, Compound I-176)
Show SMILES COc1ccc(Nc2ncc(C(=O)NC3CC3)c(Oc3cccc(NC(=O)C=C)c3)n2)cn1
Show InChI InChI=1S/C23H22N6O4/c1-3-19(30)26-15-5-4-6-17(11-15)33-22-18(21(31)27-14-7-8-14)13-25-23(29-22)28-16-9-10-20(32-2)24-12-16/h3-6,9-14H,1,7-8H2,2H3,(H,26,30)(H,27,31)(H,25,28,29)
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Celgene CAR LLC

US Patent


Assay Description
Briefly, 10× stocks of EGFR-WT (PV3872) from Invitrogen and EGFR-T790M/L858R (40350) from BPS Bioscience, San Diego, Calif., 1.13×ATP (AS001A) and ap...


US Patent US10828300 (2020)

More data for this
Ligand-Target Pair
Tyrosine-protein kinase BTK


(Homo sapiens (Human))
BDBM50161162
PNG
(AVL-292 | CC-292 | SPEBRUTINIB | Spebrutinib | US1...)
Show SMILES COCCOc1ccc(Nc2ncc(F)c(Nc3cccc(NC(=O)C=C)c3)n2)cc1
Show InChI InChI=1S/C19H18ClN3O/c20-13-9-11-7-8-21-14-6-5-10-3-1-2-4-12(10)16(14)15(11)18-17(13)22-19(24)23-18/h1-4,9,14,16,21H,5-8H2,(H2,22,23,24)/t14-,16-/m0/s1
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n/an/a<10n/an/an/an/an/an/a



Celgene CAR LLC

US Patent


Assay Description
Briefly, 10× stocks of EGFR-WT (PV3872) from Invitrogen and EGFR-T790M/L858R (40350) from BPS Bioscience, San Diego, Calif., 1.13×ATP (AS001A) and ap...


US Patent US10828300 (2020)

More data for this
Ligand-Target Pair
Tyrosine-protein kinase BTK


(Homo sapiens (Human))
BDBM397241
PNG
(US10596172, Compound I-195 | US10828300, Compound ...)
Show SMILES COc1cccc(Nc2ncc(F)c(N[C@@H]3CCCN(C3)C(=O)C=C)n2)c1
Show InChI InChI=1S/C19H22FN5O2/c1-3-17(26)25-9-5-7-14(12-25)22-18-16(20)11-21-19(24-18)23-13-6-4-8-15(10-13)27-2/h3-4,6,8,10-11,14H,1,5,7,9,12H2,2H3,(H2,21,22,23,24)/t14-/m1/s1
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Celgene CAR LLC

US Patent


Assay Description
Briefly, 10× stocks of EGFR-WT (PV3872) from Invitrogen and EGFR-T790M/L858R (40350) from BPS Bioscience, San Diego, Calif., 1.13×ATP (AS001A) and ap...


US Patent US10828300 (2020)

More data for this
Ligand-Target Pair
Tyrosine-protein kinase BTK


(Homo sapiens (Human))
BDBM397242
PNG
(US10596172, Compound I-198 | US10828300, Compound ...)
Show SMILES CC(C)(C)OC(=O)NCCCOc1ccc(Nc2ncc(F)c(Nc3cccc(NC(=O)C=C)c3)n2)cc1
Show InChI InChI=1S/C27H31FN6O4/c1-5-23(35)31-19-8-6-9-20(16-19)32-24-22(28)17-30-25(34-24)33-18-10-12-21(13-11-18)37-15-7-14-29-26(36)38-27(2,3)4/h5-6,8-13,16-17H,1,7,14-15H2,2-4H3,(H,29,36)(H,31,35)(H2,30,32,33,34)
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Celgene CAR LLC

US Patent


Assay Description
Briefly, 10× stocks of EGFR-WT (PV3872) from Invitrogen and EGFR-T790M/L858R (40350) from BPS Bioscience, San Diego, Calif., 1.13×ATP (AS001A) and ap...


US Patent US10828300 (2020)

More data for this
Ligand-Target Pair
Tyrosine-protein kinase BTK


(Homo sapiens (Human))
BDBM397249
PNG
(US10596172, Compound I-208 | US10828300, Compound ...)
Show SMILES Fc1cnc(Nc2cccc(OCCCN3CCOCC3)c2)nc1Nc1cccc(NC(=O)C=C)c1
Show InChI InChI=1S/C26H29FN6O3/c1-2-24(34)29-19-6-3-7-20(16-19)30-25-23(27)18-28-26(32-25)31-21-8-4-9-22(17-21)36-13-5-10-33-11-14-35-15-12-33/h2-4,6-9,16-18H,1,5,10-15H2,(H,29,34)(H2,28,30,31,32)
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Celgene CAR LLC

US Patent


Assay Description
Briefly, 10× stocks of EGFR-WT (PV3872) from Invitrogen and EGFR-T790M/L858R (40350) from BPS Bioscience, San Diego, Calif., 1.13×ATP (AS001A) and ap...


US Patent US10828300 (2020)

More data for this
Ligand-Target Pair
Tyrosine-protein kinase BTK


(Homo sapiens (Human))
BDBM397250
PNG
(US10596172, Compound I-209 | US10828300, Compound ...)
Show SMILES COc1ccc(Nc2ncc(C(N)=O)c(Nc3cccc(NC(=O)C=C)c3)n2)cn1
Show InChI InChI=1S/C20H19N7O3/c1-3-16(28)24-12-5-4-6-13(9-12)25-19-15(18(21)29)11-23-20(27-19)26-14-7-8-17(30-2)22-10-14/h3-11H,1H2,2H3,(H2,21,29)(H,24,28)(H2,23,25,26,27)
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Celgene CAR LLC

US Patent


Assay Description
Briefly, 10× stocks of EGFR-WT (PV3872) from Invitrogen and EGFR-T790M/L858R (40350) from BPS Bioscience, San Diego, Calif., 1.13×ATP (AS001A) and ap...


US Patent US10828300 (2020)

More data for this
Ligand-Target Pair
Tyrosine-protein kinase BTK


(Homo sapiens (Human))
BDBM397261
PNG
(US10596172, Compound I-237 | US10828300, Compound ...)
Show SMILES Cc1cnc(Nc2cccc(OCCCNC(=O)CCCC[C@@H]3SC[C@@H]4NC(=O)N[C@H]34)c2)nc1Nc1cccc(NC(=O)C=C)c1
Show InChI InChI=1S/C33H40N8O4S/c1-3-28(42)36-22-9-6-10-23(17-22)37-31-21(2)19-35-32(41-31)38-24-11-7-12-25(18-24)45-16-8-15-34-29(43)14-5-4-13-27-30-26(20-46-27)39-33(44)40-30/h3,6-7,9-12,17-19,26-27,30H,1,4-5,8,13-16,20H2,2H3,(H,34,43)(H,36,42)(H2,39,40,44)(H2,35,37,38,41)/t26-,27-,30-/m0/s1
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Celgene CAR LLC

US Patent


Assay Description
Briefly, 10× stocks of EGFR-WT (PV3872) from Invitrogen and EGFR-T790M/L858R (40350) from BPS Bioscience, San Diego, Calif., 1.13×ATP (AS001A) and ap...


US Patent US10828300 (2020)

More data for this
Ligand-Target Pair
Tyrosine-protein kinase BTK


(Homo sapiens (Human))
BDBM397268
PNG
(US10596172, Compound I-249 | US10828300, Compound ...)
Show SMILES CC(C)(O)COc1cc(Nc2ncc(F)c(Nc3cccc(NC(=O)C=C)c3)n2)ccc1Cl
Show InChI InChI=1S/C23H23ClFN5O3/c1-4-20(31)27-14-6-5-7-15(10-14)28-21-18(25)12-26-22(30-21)29-16-8-9-17(24)19(11-16)33-13-23(2,3)32/h4-12,32H,1,13H2,2-3H3,(H,27,31)(H2,26,28,29,30)
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Celgene CAR LLC

US Patent


Assay Description
Briefly, 10× stocks of EGFR-WT (PV3872) from Invitrogen and EGFR-T790M/L858R (40350) from BPS Bioscience, San Diego, Calif., 1.13×ATP (AS001A) and ap...


US Patent US10828300 (2020)

More data for this
Ligand-Target Pair
Tyrosine-protein kinase BTK


(Homo sapiens (Human))
BDBM397368
PNG
(US10596172, Compound I-312 | US10828300, Compound ...)
Show SMILES CC(C)(O)COc1ccc(Nc2ncc(F)c(Nc3cccc(c3)C(O)C(=C)C#N)n2)cn1
Show InChI InChI=1S/C23H23FN6O3/c1-14(10-25)20(31)15-5-4-6-16(9-15)28-21-18(24)12-27-22(30-21)29-17-7-8-19(26-11-17)33-13-23(2,3)32/h4-9,11-12,20,31-32H,1,13H2,2-3H3,(H2,27,28,29,30)
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n/an/a<10n/an/an/an/an/an/a



Celgene CAR LLC

US Patent


Assay Description
Briefly, 10× stocks of EGFR-WT (PV3872) from Invitrogen and EGFR-T790M/L858R (40350) from BPS Bioscience, San Diego, Calif., 1.13×ATP (AS001A) and ap...


US Patent US10828300 (2020)

More data for this
Ligand-Target Pair
Tyrosine-protein kinase BTK


(Homo sapiens (Human))
BDBM397272
PNG
(US10596172, Compound I-318 | US10828300, Compound ...)
Show SMILES CS(=O)(=O)CCCOc1ccc(Nc2ncc(F)c(Nc3cccc(NC(=O)C=C)c3)n2)cc1F
Show InChI InChI=1S/C23H23F2N5O4S/c1-3-21(31)27-15-6-4-7-16(12-15)28-22-19(25)14-26-23(30-22)29-17-8-9-20(18(24)13-17)34-10-5-11-35(2,32)33/h3-4,6-9,12-14H,1,5,10-11H2,2H3,(H,27,31)(H2,26,28,29,30)
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Celgene CAR LLC

US Patent


Assay Description
Briefly, 10× stocks of EGFR-WT (PV3872) from Invitrogen and EGFR-T790M/L858R (40350) from BPS Bioscience, San Diego, Calif., 1.13×ATP (AS001A) and ap...


US Patent US10828300 (2020)

More data for this
Ligand-Target Pair
Tyrosine-protein kinase BTK


(Homo sapiens (Human))
BDBM397379
PNG
(US10596172, Compound I-339 | US10828300, Compound ...)
Show SMILES OCC(O)COc1cccc(Nc2ncc(F)c(Nc3cccc(NC(=O)C=C)c3)n2)c1
Show InChI InChI=1S/C22H22FN5O4/c1-2-20(31)25-14-5-3-6-15(9-14)26-21-19(23)11-24-22(28-21)27-16-7-4-8-18(10-16)32-13-17(30)12-29/h2-11,17,29-30H,1,12-13H2,(H,25,31)(H2,24,26,27,28)
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Celgene CAR LLC

US Patent


Assay Description
Briefly, 10× stocks of EGFR-WT (PV3872) from Invitrogen and EGFR-T790M/L858R (40350) from BPS Bioscience, San Diego, Calif., 1.13×ATP (AS001A) and ap...


US Patent US10828300 (2020)

More data for this
Ligand-Target Pair
Tyrosine-protein kinase BTK


(Homo sapiens (Human))
BDBM397390
PNG
(US10596172, Compound I-352 | US10828300, Compound ...)
Show SMILES COCCOc1ccc(Nc2ncc(c(Nc3cccc(NC(=O)C=C)c3)n2)C(F)(F)F)cc1F
Show InChI InChI=1S/C23H21F4N5O3/c1-3-20(33)29-14-5-4-6-15(11-14)30-21-17(23(25,26)27)13-28-22(32-21)31-16-7-8-19(18(24)12-16)35-10-9-34-2/h3-8,11-13H,1,9-10H2,2H3,(H,29,33)(H2,28,30,31,32)
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n/an/a<10n/an/an/an/an/an/a



Celgene CAR LLC

US Patent


Assay Description
Briefly, 10× stocks of EGFR-WT (PV3872) from Invitrogen and EGFR-T790M/L858R (40350) from BPS Bioscience, San Diego, Calif., 1.13×ATP (AS001A) and ap...


US Patent US10828300 (2020)

More data for this
Ligand-Target Pair
Tyrosine-protein kinase BTK


(Homo sapiens (Human))
BDBM397281
PNG
(US10596172, Compound I-353 | US10828300, Compound ...)
Show SMILES OCC(O)COc1cc(Nc2ncc(F)c(Nc3cccc(NC(=O)C=C)c3)n2)ccc1Cl
Show InChI InChI=1S/C22H21ClFN5O4/c1-2-20(32)26-13-4-3-5-14(8-13)27-21-18(24)10-25-22(29-21)28-15-6-7-17(23)19(9-15)33-12-16(31)11-30/h2-10,16,30-31H,1,11-12H2,(H,26,32)(H2,25,27,28,29)
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Celgene CAR LLC

US Patent


Assay Description
Briefly, 10× stocks of EGFR-WT (PV3872) from Invitrogen and EGFR-T790M/L858R (40350) from BPS Bioscience, San Diego, Calif., 1.13×ATP (AS001A) and ap...


US Patent US10828300 (2020)

More data for this
Ligand-Target Pair
Tyrosine-protein kinase BTK


(Homo sapiens (Human))
BDBM397283
PNG
(US10596172, Compound I-355 | US10828300, Compound ...)
Show SMILES O[C@H]1CN[C@H](COc2ccc(Nc3ncc(F)c(Nc4cccc(NC(=O)C=C)c4)n3)cc2F)C1
Show InChI InChI=1S/C24H24F2N6O3/c1-2-22(34)29-14-4-3-5-15(8-14)30-23-20(26)12-28-24(32-23)31-16-6-7-21(19(25)10-16)35-13-17-9-18(33)11-27-17/h2-8,10,12,17-18,27,33H,1,9,11,13H2,(H,29,34)(H2,28,30,31,32)/t17-,18+/m0/s1
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Celgene CAR LLC

US Patent


Assay Description
Briefly, 10× stocks of EGFR-WT (PV3872) from Invitrogen and EGFR-T790M/L858R (40350) from BPS Bioscience, San Diego, Calif., 1.13×ATP (AS001A) and ap...


US Patent US10828300 (2020)

More data for this
Ligand-Target Pair
Tyrosine-protein kinase BTK


(Homo sapiens (Human))
BDBM397285
PNG
(US10596172, Compound I-357 | US10828300, Compound ...)
Show SMILES C[C@@H](CO)Oc1cc(Nc2ncc(F)c(Nc3cccc(NC(=O)C=C)c3)n2)ccc1Cl
Show InChI InChI=1S/C22H21ClFN5O3/c1-3-20(31)26-14-5-4-6-15(9-14)27-21-18(24)11-25-22(29-21)28-16-7-8-17(23)19(10-16)32-13(2)12-30/h3-11,13,30H,1,12H2,2H3,(H,26,31)(H2,25,27,28,29)/t13-/m0/s1
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Celgene CAR LLC

US Patent


Assay Description
Briefly, 10× stocks of EGFR-WT (PV3872) from Invitrogen and EGFR-T790M/L858R (40350) from BPS Bioscience, San Diego, Calif., 1.13×ATP (AS001A) and ap...


US Patent US10828300 (2020)

More data for this
Ligand-Target Pair
Tyrosine-protein kinase BTK


(Homo sapiens (Human))
BDBM397391
PNG
(US10596172, Compound I-358 | US10828300, Compound ...)
Show SMILES C[C@H](CO)Oc1cc(Nc2ncc(F)c(Nc3cccc(NC(=O)C=C)c3)n2)ccc1Cl
Show InChI InChI=1S/C22H21ClFN5O3/c1-3-20(31)26-14-5-4-6-15(9-14)27-21-18(24)11-25-22(29-21)28-16-7-8-17(23)19(10-16)32-13(2)12-30/h3-11,13,30H,1,12H2,2H3,(H,26,31)(H2,25,27,28,29)/t13-/m1/s1
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n/an/a<10n/an/an/an/an/an/a



Celgene CAR LLC

US Patent


Assay Description
Briefly, 10× stocks of EGFR-WT (PV3872) from Invitrogen and EGFR-T790M/L858R (40350) from BPS Bioscience, San Diego, Calif., 1.13×ATP (AS001A) and ap...


US Patent US10828300 (2020)

More data for this
Ligand-Target Pair
Tyrosine-protein kinase BTK


(Homo sapiens (Human))
BDBM397286
PNG
(US10596172, Compound I-359 | US10828300, Compound ...)
Show SMILES COCCOCCOc1ccc(Nc2ncc(F)c(Nc3cccc(NC(=O)C=C)c3)n2)cc1F
Show InChI InChI=1S/C24H25F2N5O4/c1-3-22(32)28-16-5-4-6-17(13-16)29-23-20(26)15-27-24(31-23)30-18-7-8-21(19(25)14-18)35-12-11-34-10-9-33-2/h3-8,13-15H,1,9-12H2,2H3,(H,28,32)(H2,27,29,30,31)
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Celgene CAR LLC

US Patent


Assay Description
Briefly, 10× stocks of EGFR-WT (PV3872) from Invitrogen and EGFR-T790M/L858R (40350) from BPS Bioscience, San Diego, Calif., 1.13×ATP (AS001A) and ap...


US Patent US10828300 (2020)

More data for this
Ligand-Target Pair
Tyrosine-protein kinase BTK


(Homo sapiens (Human))
BDBM397289
PNG
(US10596172, Compound I-5 | US10828300, Compound I-...)
Show SMILES Cc1cnc(Nc2cccc(NC(=O)C=C)c2)nc1Nc1ccccc1
Show InChI InChI=1S/C20H19N5O/c1-3-18(26)22-16-10-7-11-17(12-16)24-20-21-13-14(2)19(25-20)23-15-8-5-4-6-9-15/h3-13H,1H2,2H3,(H,22,26)(H2,21,23,24,25)
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Celgene CAR LLC

US Patent


Assay Description
Briefly, 10× stocks of EGFR-WT (PV3872) from Invitrogen and EGFR-T790M/L858R (40350) from BPS Bioscience, San Diego, Calif., 1.13×ATP (AS001A) and ap...


US Patent US10828300 (2020)

More data for this
Ligand-Target Pair
Tyrosine-protein kinase BTK


(Homo sapiens (Human))
BDBM397293
PNG
(US10596172, Compound I-11 | US10828300, Compound I...)
Show SMILES Cc1cnc(Nc2cccc(c2)S(N)(=O)=O)nc1Nc1ccc2CN(CCc2c1)C(=O)CCl
Show InChI InChI=1S/C22H23ClN6O3S/c1-14-12-25-22(27-17-3-2-4-19(10-17)33(24,31)32)28-21(14)26-18-6-5-16-13-29(20(30)11-23)8-7-15(16)9-18/h2-6,9-10,12H,7-8,11,13H2,1H3,(H2,24,31,32)(H2,25,26,27,28)
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n/an/a<10n/an/an/an/an/an/a



Celgene CAR LLC

US Patent


Assay Description
Briefly, 10× stocks of EGFR-WT (PV3872) from Invitrogen and EGFR-T790M/L858R (40350) from BPS Bioscience, San Diego, Calif., 1.13×ATP (AS001A) and ap...


US Patent US10828300 (2020)

More data for this
Ligand-Target Pair
Tyrosine-protein kinase BTK


(Homo sapiens (Human))
BDBM397146
PNG
(US10596172, Compound I-27 | US10828300, Compound I...)
Show SMILES Cc1cnc(Nc2ccccc2)nc1NC1CCCN(C1)C(=O)C=C
Show InChI InChI=1S/C19H23N5O/c1-3-17(25)24-11-7-10-16(13-24)21-18-14(2)12-20-19(23-18)22-15-8-5-4-6-9-15/h3-6,8-9,12,16H,1,7,10-11,13H2,2H3,(H2,20,21,22,23)
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n/an/a<10n/an/an/an/an/an/a



Celgene CAR LLC

US Patent


Assay Description
Briefly, 10× stocks of EGFR-WT (PV3872) from Invitrogen and EGFR-T790M/L858R (40350) from BPS Bioscience, San Diego, Calif., 1.13×ATP (AS001A) and ap...


US Patent US10828300 (2020)

More data for this
Ligand-Target Pair
Tyrosine-protein kinase BTK


(Homo sapiens (Human))
BDBM397154
PNG
(US10596172, Compound I-54 | US10828300, Compound I...)
Show SMILES Fc1cnc(Nc2ccc(O[C@H]3CCOC3)nc2)nc1Nc1cccc(NC(=O)C=C)c1
Show InChI InChI=1S/C22H21FN6O3/c1-2-19(30)26-14-4-3-5-15(10-14)27-21-18(23)12-25-22(29-21)28-16-6-7-20(24-11-16)32-17-8-9-31-13-17/h2-7,10-12,17H,1,8-9,13H2,(H,26,30)(H2,25,27,28,29)/t17-/m0/s1
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n/an/a<10n/an/an/an/an/an/a



Celgene CAR LLC

US Patent


Assay Description
Briefly, 10× stocks of EGFR-WT (PV3872) from Invitrogen and EGFR-T790M/L858R (40350) from BPS Bioscience, San Diego, Calif., 1.13×ATP (AS001A) and ap...


US Patent US10828300 (2020)

More data for this
Ligand-Target Pair
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* indicates data uncertainty>20%