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Patent code US10829446

Compile Data Set for Download or QSAR
Found 156 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Histone acetyltransferase KAT6A


(Homo sapiens)
BDBM50527298
PNG
(CHEMBL4571483 | US10829446, Compound 152)
Show SMILES Cc1cc(cc(C(=O)NNS(=O)(=O)c2ccccc2)c1F)-c1ccco1
Show InChI InChI=1S/C18H15FN2O4S/c1-12-10-13(16-8-5-9-25-16)11-15(17(12)19)18(22)20-21-26(23,24)14-6-3-2-4-7-14/h2-11,21H,1H3,(H,20,22)
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
n/an/a 8n/an/an/an/an/an/a


TBA

Assay Description
Active Moz protein was expressed as N-terminal fusion protein with a His6 tag in BL21 E. coli cells. Protein purification was performed via nickel-im...


Citation and Details
More data for this
Ligand-Target Pair
Histone acetyltransferase KAT6A


(Homo sapiens)
BDBM471919
PNG
(US10829446, Compound 154)
Show SMILES Cc1cc(c(F)c(C(=O)NNS(=O)(=O)c2ccccc2)c1F)-c1ccccc1
Show InChI InChI=1S/C20H16F2N2O3S/c1-13-12-16(14-8-4-2-5-9-14)19(22)17(18(13)21)20(25)23-24-28(26,27)15-10-6-3-7-11-15/h2-12,24H,1H3,(H,23,25)
PDB

UniProtKB/SwissProt

GoogleScholar
UniChem
n/an/a 10n/an/an/an/an/an/a


TBA

Assay Description
Active Moz protein was expressed as N-terminal fusion protein with a His6 tag in BL21 E. coli cells. Protein purification was performed via nickel-im...


Citation and Details
More data for this
Ligand-Target Pair
Histone acetyltransferase KAT6A


(Homo sapiens)
BDBM50527243
PNG
(CHEMBL4458272 | US10829446, Compound 153)
Show SMILES Cc1cc(cc(c1)-c1ccco1)C(=O)NNS(=O)(=O)c1ccccc1F
Show InChI InChI=1S/C18H15FN2O4S/c1-12-9-13(16-6-4-8-25-16)11-14(10-12)18(22)20-21-26(23,24)17-7-3-2-5-15(17)19/h2-11,21H,1H3,(H,20,22)
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
n/an/a 10n/an/an/an/an/an/a


TBA

Assay Description
Active Moz protein was expressed as N-terminal fusion protein with a His6 tag in BL21 E. coli cells. Protein purification was performed via nickel-im...


Citation and Details
More data for this
Ligand-Target Pair
Histone acetyltransferase KAT6A


(Homo sapiens)
BDBM50518867
PNG
(CHEMBL4460509 | US10829446, Compound 157)
Show SMILES Fc1ccc(cc1C(=O)NNS(=O)(=O)c1ccccc1)-c1ccccc1
Show InChI InChI=1S/C19H15FN2O3S/c20-18-12-11-15(14-7-3-1-4-8-14)13-17(18)19(23)21-22-26(24,25)16-9-5-2-6-10-16/h1-13,22H,(H,21,23)
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
PDB
UniChem
n/an/a 17n/an/an/an/an/an/a


TBA

Assay Description
Active Moz protein was expressed as N-terminal fusion protein with a His6 tag in BL21 E. coli cells. Protein purification was performed via nickel-im...


Citation and Details
More data for this
Ligand-Target Pair
Histone acetyltransferase KAT6A


(Homo sapiens)
BDBM50527325
PNG
(CHEMBL4461380 | US10829446, Compound 87)
Show SMILES Cc1cc(cc(C(=O)NNS(=O)(=O)c2ccccc2)c1F)-n1nccn1
Show InChI InChI=1S/C16H14FN5O3S/c1-11-9-12(22-18-7-8-19-22)10-14(15(11)17)16(23)20-21-26(24,25)13-5-3-2-4-6-13/h2-10,21H,1H3,(H,20,23)
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
n/an/a 41n/an/an/an/an/an/a


TBA

Assay Description
Active Moz protein was expressed as N-terminal fusion protein with a His6 tag in BL21 E. coli cells. Protein purification was performed via nickel-im...


Citation and Details
More data for this
Ligand-Target Pair
Histone acetyltransferase KAT6A


(Homo sapiens)
BDBM50527227
PNG
(CHEMBL4450971 | US10829446, Compound 150)
Show SMILES Fc1ccccc1S(=O)(=O)NNC(=O)c1cccc(OCC=C)c1
Show InChI InChI=1S/C16H15FN2O4S/c1-2-10-23-13-7-5-6-12(11-13)16(20)18-19-24(21,22)15-9-4-3-8-14(15)17/h2-9,11,19H,1,10H2,(H,18,20)
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
n/an/a 43n/an/an/an/an/an/a


TBA

Assay Description
Active Moz protein was expressed as N-terminal fusion protein with a His6 tag in BL21 E. coli cells. Protein purification was performed via nickel-im...


Citation and Details
More data for this
Ligand-Target Pair
Histone acetyltransferase KAT6A


(Homo sapiens)
BDBM50527366
PNG
(CHEMBL4449163 | US10829446, Compound 139)
Show SMILES CC(C)Oc1cc(C)cc(c1)C(=O)NNS(=O)(=O)c1ccccc1F
Show InChI InChI=1S/C17H19FN2O4S/c1-11(2)24-14-9-12(3)8-13(10-14)17(21)19-20-25(22,23)16-7-5-4-6-15(16)18/h4-11,20H,1-3H3,(H,19,21)
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
n/an/a 43n/an/an/an/an/an/a


TBA

Assay Description
Active Moz protein was expressed as N-terminal fusion protein with a His6 tag in BL21 E. coli cells. Protein purification was performed via nickel-im...


Citation and Details
More data for this
Ligand-Target Pair
Histone acetyltransferase KAT6A


(Homo sapiens)
BDBM50527348
PNG
(CHEMBL4454507 | US10829446, Compound 59)
Show SMILES Cc1cc(cc(c1)-n1cccn1)C(=O)NNS(=O)(=O)c1ccccc1F
Show InChI InChI=1S/C17H15FN4O3S/c1-12-9-13(11-14(10-12)22-8-4-7-19-22)17(23)20-21-26(24,25)16-6-3-2-5-15(16)18/h2-11,21H,1H3,(H,20,23)
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
n/an/a 47n/an/an/an/an/an/a


TBA

Assay Description
Active Moz protein was expressed as N-terminal fusion protein with a His6 tag in BL21 E. coli cells. Protein purification was performed via nickel-im...


Citation and Details
More data for this
Ligand-Target Pair
Histone acetyltransferase KAT6A


(Homo sapiens)
BDBM50527303
PNG
(CHEMBL4464572 | US10829446, Compound 95)
Show SMILES Cc1cc(OCC=C)cc(C(=O)NNS(=O)(=O)c2ccccc2)c1F
Show InChI InChI=1S/C17H17FN2O4S/c1-3-9-24-13-10-12(2)16(18)15(11-13)17(21)19-20-25(22,23)14-7-5-4-6-8-14/h3-8,10-11,20H,1,9H2,2H3,(H,19,21)
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
n/an/a 50n/an/an/an/an/an/a


TBA

Assay Description
Active Moz protein was expressed as N-terminal fusion protein with a His6 tag in BL21 E. coli cells. Protein purification was performed via nickel-im...


Citation and Details
More data for this
Ligand-Target Pair
Histone acetyltransferase KAT6A


(Homo sapiens)
BDBM50527355
PNG
(CHEMBL4456585 | US10829446, Compound 46)
Show SMILES Fc1cc(cc(c1)-c1ccccn1)C(=O)NNS(=O)(=O)c1ccccc1F
Show InChI InChI=1S/C18H13F2N3O3S/c19-14-10-12(16-6-3-4-8-21-16)9-13(11-14)18(24)22-23-27(25,26)17-7-2-1-5-15(17)20/h1-11,23H,(H,22,24)
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
PDB
UniChem
n/an/a 51n/an/an/an/an/an/a


TBA

Assay Description
Active Moz protein was expressed as N-terminal fusion protein with a His6 tag in BL21 E. coli cells. Protein purification was performed via nickel-im...


Citation and Details
More data for this
Ligand-Target Pair
Histone acetyltransferase KAT6A


(Homo sapiens)
BDBM50527304
PNG
(CHEMBL4560554 | US10829446, Compound 113)
Show SMILES CCCOc1cc(C)c(F)c(c1)C(=O)NNS(=O)(=O)c1ccccc1
Show InChI InChI=1S/C17H19FN2O4S/c1-3-9-24-13-10-12(2)16(18)15(11-13)17(21)19-20-25(22,23)14-7-5-4-6-8-14/h4-8,10-11,20H,3,9H2,1-2H3,(H,19,21)
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
n/an/a 52n/an/an/an/an/an/a


TBA

Assay Description
Active Moz protein was expressed as N-terminal fusion protein with a His6 tag in BL21 E. coli cells. Protein purification was performed via nickel-im...


Citation and Details
More data for this
Ligand-Target Pair
Histone acetyltransferase KAT6A


(Homo sapiens)
BDBM471901
PNG
(US10829446, Compound 136)
Show SMILES Fc1ccc(OC=C)cc1C(=O)NNS(=O)(=O)c1ccccc1
Show InChI InChI=1S/C15H13FN2O4S/c1-2-22-11-8-9-14(16)13(10-11)15(19)17-18-23(20,21)12-6-4-3-5-7-12/h2-10,18H,1H2,(H,17,19)
PDB

UniProtKB/SwissProt

GoogleScholar
UniChem
n/an/a 53n/an/an/an/an/an/a


TBA

Assay Description
Active Moz protein was expressed as N-terminal fusion protein with a His6 tag in BL21 E. coli cells. Protein purification was performed via nickel-im...


Citation and Details
More data for this
Ligand-Target Pair
Histone acetyltransferase KAT6A


(Homo sapiens)
BDBM50527346
PNG
(CHEMBL4566403 | US10829446, Compound 88)
Show SMILES Cc1cc(cc(c1)-n1nccn1)C(=O)NNS(=O)(=O)c1ccccc1F
Show InChI InChI=1S/C16H14FN5O3S/c1-11-8-12(10-13(9-11)22-18-6-7-19-22)16(23)20-21-26(24,25)15-5-3-2-4-14(15)17/h2-10,21H,1H3,(H,20,23)
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
n/an/a 54n/an/an/an/an/an/a


TBA

Assay Description
Active Moz protein was expressed as N-terminal fusion protein with a His6 tag in BL21 E. coli cells. Protein purification was performed via nickel-im...


Citation and Details
More data for this
Ligand-Target Pair
Histone acetyltransferase KAT6A


(Homo sapiens)
BDBM50527302
PNG
(CHEMBL4573736 | US10829446, Compound 146)
Show SMILES CC(=C)COc1cc(C)c(F)c(c1)C(=O)NNS(=O)(=O)c1ccccc1
Show InChI InChI=1S/C18H19FN2O4S/c1-12(2)11-25-14-9-13(3)17(19)16(10-14)18(22)20-21-26(23,24)15-7-5-4-6-8-15/h4-10,21H,1,11H2,2-3H3,(H,20,22)
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
n/an/a 55n/an/an/an/an/an/a


TBA

Assay Description
Active Moz protein was expressed as N-terminal fusion protein with a His6 tag in BL21 E. coli cells. Protein purification was performed via nickel-im...


Citation and Details
More data for this
Ligand-Target Pair
Histone acetyltransferase KAT6A


(Homo sapiens)
BDBM50518832
PNG
(CHEMBL4455897 | US10829446, Compound 36)
Show SMILES Cc1cc(cc(C(=O)NNS(=O)(=O)c2ccccc2)c1F)-c1ccccc1
Show InChI InChI=1S/C20H17FN2O3S/c1-14-12-16(15-8-4-2-5-9-15)13-18(19(14)21)20(24)22-23-27(25,26)17-10-6-3-7-11-17/h2-13,23H,1H3,(H,22,24)
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
PDB
UniChem
n/an/a 55n/an/an/an/an/an/a


TBA

Assay Description
Active Moz protein was expressed as N-terminal fusion protein with a His6 tag in BL21 E. coli cells. Protein purification was performed via nickel-im...


Citation and Details
More data for this
Ligand-Target Pair
Histone acetyltransferase KAT6A


(Homo sapiens)
BDBM50527246
PNG
(CHEMBL4445473 | US10829446, Compound 84)
Show SMILES Cc1ccnn1-c1cc(C)cc(c1)C(=O)NNS(=O)(=O)c1ccccc1F
Show InChI InChI=1S/C18H17FN4O3S/c1-12-9-14(11-15(10-12)23-13(2)7-8-20-23)18(24)21-22-27(25,26)17-6-4-3-5-16(17)19/h3-11,22H,1-2H3,(H,21,24)
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
n/an/a 58n/an/an/an/an/an/a


TBA

Assay Description
Active Moz protein was expressed as N-terminal fusion protein with a His6 tag in BL21 E. coli cells. Protein purification was performed via nickel-im...


Citation and Details
More data for this
Ligand-Target Pair
Histone acetyltransferase KAT6A


(Homo sapiens)
BDBM50527250
PNG
(CHEMBL4475883 | US10829446, Compound 67)
Show SMILES Cc1ccn(n1)-c1cc(C)cc(c1)C(=O)NNS(=O)(=O)c1ccccc1F
Show InChI InChI=1S/C18H17FN4O3S/c1-12-9-14(11-15(10-12)23-8-7-13(2)21-23)18(24)20-22-27(25,26)17-6-4-3-5-16(17)19/h3-11,22H,1-2H3,(H,20,24)
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
n/an/a 60n/an/an/an/an/an/a


TBA

Assay Description
Active Moz protein was expressed as N-terminal fusion protein with a His6 tag in BL21 E. coli cells. Protein purification was performed via nickel-im...


Citation and Details
More data for this
Ligand-Target Pair
Histone acetyltransferase KAT6A


(Homo sapiens)
BDBM50527377
PNG
(CHEMBL4474916 | US10829446, Compound 134)
Show SMILES CC(C)Oc1ccc(F)c(c1)C(=O)NNS(=O)(=O)c1ccccc1
Show InChI InChI=1S/C16H17FN2O4S/c1-11(2)23-12-8-9-15(17)14(10-12)16(20)18-19-24(21,22)13-6-4-3-5-7-13/h3-11,19H,1-2H3,(H,18,20)
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
n/an/a 60n/an/an/an/an/an/a


TBA

Assay Description
Active Moz protein was expressed as N-terminal fusion protein with a His6 tag in BL21 E. coli cells. Protein purification was performed via nickel-im...


Citation and Details
More data for this
Ligand-Target Pair
Histone acetyltransferase KAT6A


(Homo sapiens)
BDBM50527365
PNG
(CHEMBL4455027 | US10829446, Compound 91)
Show SMILES Fc1cc(OCC=C)cc(c1)C(=O)NNS(=O)(=O)c1ccccc1F
Show InChI InChI=1S/C16H14F2N2O4S/c1-2-7-24-13-9-11(8-12(17)10-13)16(21)19-20-25(22,23)15-6-4-3-5-14(15)18/h2-6,8-10,20H,1,7H2,(H,19,21)
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
n/an/a 60n/an/an/an/an/an/a


TBA

Assay Description
Active Moz protein was expressed as N-terminal fusion protein with a His6 tag in BL21 E. coli cells. Protein purification was performed via nickel-im...


Citation and Details
More data for this
Ligand-Target Pair
Histone acetyltransferase KAT6A


(Homo sapiens)
BDBM50527353
PNG
(CHEMBL4524297 | US10829446, Compound 94)
Show SMILES Cc1cc(OCC2CC2)cc(C(=O)NNS(=O)(=O)c2ccccc2)c1F
Show InChI InChI=1S/C18H19FN2O4S/c1-12-9-14(25-11-13-7-8-13)10-16(17(12)19)18(22)20-21-26(23,24)15-5-3-2-4-6-15/h2-6,9-10,13,21H,7-8,11H2,1H3,(H,20,22)
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
n/an/a 61n/an/an/an/an/an/a


TBA

Assay Description
Active Moz protein was expressed as N-terminal fusion protein with a His6 tag in BL21 E. coli cells. Protein purification was performed via nickel-im...


Citation and Details
More data for this
Ligand-Target Pair
Histone acetyltransferase KAT6A


(Homo sapiens)
BDBM50527230
PNG
(CHEMBL4581401 | US10829446, Compound 60)
Show SMILES Cc1cc(cc(C(=O)NNS(=O)(=O)c2ccccc2)c1F)-n1cccn1
Show InChI InChI=1S/C17H15FN4O3S/c1-12-10-13(22-9-5-8-19-22)11-15(16(12)18)17(23)20-21-26(24,25)14-6-3-2-4-7-14/h2-11,21H,1H3,(H,20,23)
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
n/an/a 62n/an/an/an/an/an/a


TBA

Assay Description
Active Moz protein was expressed as N-terminal fusion protein with a His6 tag in BL21 E. coli cells. Protein purification was performed via nickel-im...


Citation and Details
More data for this
Ligand-Target Pair
Histone acetyltransferase KAT6A


(Homo sapiens)
BDBM50527313
PNG
(CHEMBL4446917 | US10829446, Compound 137)
Show SMILES CCOc1cc(C)cc(c1)C(=O)NNS(=O)(=O)c1ccccc1F
Show InChI InChI=1S/C16H17FN2O4S/c1-3-23-13-9-11(2)8-12(10-13)16(20)18-19-24(21,22)15-7-5-4-6-14(15)17/h4-10,19H,3H2,1-2H3,(H,18,20)
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
n/an/a 62n/an/an/an/an/an/a


TBA

Assay Description
Active Moz protein was expressed as N-terminal fusion protein with a His6 tag in BL21 E. coli cells. Protein purification was performed via nickel-im...


Citation and Details
More data for this
Ligand-Target Pair
Histone acetyltransferase KAT6A


(Homo sapiens)
BDBM50527341
PNG
(CHEMBL4443232 | US10829446, Compound 138)
Show SMILES CCOc1cc(C)c(F)c(c1)C(=O)NNS(=O)(=O)c1ccccc1
Show InChI InChI=1S/C16H17FN2O4S/c1-3-23-12-9-11(2)15(17)14(10-12)16(20)18-19-24(21,22)13-7-5-4-6-8-13/h4-10,19H,3H2,1-2H3,(H,18,20)
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
n/an/a 62n/an/an/an/an/an/a


TBA

Assay Description
Active Moz protein was expressed as N-terminal fusion protein with a His6 tag in BL21 E. coli cells. Protein purification was performed via nickel-im...


Citation and Details
More data for this
Ligand-Target Pair
Histone acetyltransferase KAT6A


(Homo sapiens)
BDBM50527218
PNG
(CHEMBL4513861 | US10829446, Compound 114)
Show SMILES CC(C)Oc1cc(C)c(F)c(c1)C(=O)NNS(=O)(=O)c1ccccc1
Show InChI InChI=1S/C17H19FN2O4S/c1-11(2)24-13-9-12(3)16(18)15(10-13)17(21)19-20-25(22,23)14-7-5-4-6-8-14/h4-11,20H,1-3H3,(H,19,21)
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
n/an/a 64n/an/an/an/an/an/a


TBA

Assay Description
Active Moz protein was expressed as N-terminal fusion protein with a His6 tag in BL21 E. coli cells. Protein purification was performed via nickel-im...


Citation and Details
More data for this
Ligand-Target Pair
Histone acetyltransferase KAT6A


(Homo sapiens)
BDBM50527311
PNG
(CHEMBL4449359 | US10829446, Compound 53)
Show SMILES Cc1cc(cc(C(=O)NNS(=O)(=O)c2ccccc2)c1F)-c1ncccn1
Show InChI InChI=1S/C18H15FN4O3S/c1-12-10-13(17-20-8-5-9-21-17)11-15(16(12)19)18(24)22-23-27(25,26)14-6-3-2-4-7-14/h2-11,23H,1H3,(H,22,24)
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
n/an/a 65n/an/an/an/an/an/a


TBA

Assay Description
Active Moz protein was expressed as N-terminal fusion protein with a His6 tag in BL21 E. coli cells. Protein purification was performed via nickel-im...


Citation and Details
More data for this
Ligand-Target Pair
Histone acetyltransferase KAT6A


(Homo sapiens)
BDBM50527240
PNG
(CHEMBL4541948 | US10829446, Compound 124)
Show SMILES Fc1ccccc1S(=O)(=O)NNC(=O)c1cccc(c1)-c1ccsc1
Show InChI InChI=1S/C17H13FN2O3S2/c18-15-6-1-2-7-16(15)25(22,23)20-19-17(21)13-5-3-4-12(10-13)14-8-9-24-11-14/h1-11,20H,(H,19,21)
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
n/an/a 66n/an/an/an/an/an/a


TBA

Assay Description
Active Moz protein was expressed as N-terminal fusion protein with a His6 tag in BL21 E. coli cells. Protein purification was performed via nickel-im...


Citation and Details
More data for this
Ligand-Target Pair
Histone acetyltransferase KAT6A


(Homo sapiens)
BDBM50527225
PNG
(CHEMBL4565790 | US10829446, Compound 101)
Show SMILES Fc1cc(cc(c1)-c1ccco1)C(=O)NNS(=O)(=O)c1ccccc1F
Show InChI InChI=1S/C17H12F2N2O4S/c18-13-9-11(15-5-3-7-25-15)8-12(10-13)17(22)20-21-26(23,24)16-6-2-1-4-14(16)19/h1-10,21H,(H,20,22)
PDB

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UniChem
n/an/a 66n/an/an/an/an/an/a


TBA

Assay Description
Active Moz protein was expressed as N-terminal fusion protein with a His6 tag in BL21 E. coli cells. Protein purification was performed via nickel-im...


Citation and Details
More data for this
Ligand-Target Pair
Histone acetyltransferase KAT6A


(Homo sapiens)
BDBM50527293
PNG
(CHEMBL4561274 | US10829446, Compound 69)
Show SMILES Cc1ccn(n1)-c1cc(C)c(F)c(c1)C(=O)NNS(=O)(=O)c1ccccc1
Show InChI InChI=1S/C18H17FN4O3S/c1-12-10-14(23-9-8-13(2)21-23)11-16(17(12)19)18(24)20-22-27(25,26)15-6-4-3-5-7-15/h3-11,22H,1-2H3,(H,20,24)
PDB

UniProtKB/SwissProt

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UniChem
n/an/a 68n/an/an/an/an/an/a


TBA

Assay Description
Active Moz protein was expressed as N-terminal fusion protein with a His6 tag in BL21 E. coli cells. Protein purification was performed via nickel-im...


Citation and Details
More data for this
Ligand-Target Pair
Histone acetyltransferase KAT6A


(Homo sapiens)
BDBM50527221
PNG
(CHEMBL4464911 | US10829446, Compound 64)
Show SMILES Fc1cc(cc(c1)-n1cccn1)C(=O)NNS(=O)(=O)c1ccccc1F
Show InChI InChI=1S/C16H12F2N4O3S/c17-12-8-11(9-13(10-12)22-7-3-6-19-22)16(23)20-21-26(24,25)15-5-2-1-4-14(15)18/h1-10,21H,(H,20,23)
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UniProtKB/SwissProt

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n/an/a 70n/an/an/an/an/an/a


TBA

Assay Description
Active Moz protein was expressed as N-terminal fusion protein with a His6 tag in BL21 E. coli cells. Protein purification was performed via nickel-im...


Citation and Details
More data for this
Ligand-Target Pair
Histone acetyltransferase KAT6A


(Homo sapiens)
BDBM471920
PNG
(US10829446, Compound 155)
Show SMILES Cc1cc(c(F)c(C(=O)NNS(=O)(=O)c2ccccc2)c1F)-n1cccn1
Show InChI InChI=1S/C17H14F2N4O3S/c1-11-10-13(23-9-5-8-20-23)16(19)14(15(11)18)17(24)21-22-27(25,26)12-6-3-2-4-7-12/h2-10,22H,1H3,(H,21,24)
PDB

UniProtKB/SwissProt

GoogleScholar
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n/an/a 71n/an/an/an/an/an/a


TBA

Assay Description
Active Moz protein was expressed as N-terminal fusion protein with a His6 tag in BL21 E. coli cells. Protein purification was performed via nickel-im...


Citation and Details
More data for this
Ligand-Target Pair
Histone acetyltransferase KAT6A


(Homo sapiens)
BDBM50527334
PNG
(CHEMBL4453580 | US10829446, Compound 111)
Show SMILES CCCOc1cc(F)cc(c1)C(=O)NNS(=O)(=O)c1ccccc1F
Show InChI InChI=1S/C16H16F2N2O4S/c1-2-7-24-13-9-11(8-12(17)10-13)16(21)19-20-25(22,23)15-6-4-3-5-14(15)18/h3-6,8-10,20H,2,7H2,1H3,(H,19,21)
PDB

UniProtKB/SwissProt

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n/an/a 72n/an/an/an/an/an/a


TBA

Assay Description
Active Moz protein was expressed as N-terminal fusion protein with a His6 tag in BL21 E. coli cells. Protein purification was performed via nickel-im...


Citation and Details
More data for this
Ligand-Target Pair
Histone acetyltransferase KAT6A


(Homo sapiens)
BDBM50527235
PNG
(CHEMBL4516984 | US10829446, Compound 52)
Show SMILES Fc1cc(cc(c1)-c1ncccn1)C(=O)NNS(=O)(=O)c1ccccc1F
Show InChI InChI=1S/C17H12F2N4O3S/c18-13-9-11(16-20-6-3-7-21-16)8-12(10-13)17(24)22-23-27(25,26)15-5-2-1-4-14(15)19/h1-10,23H,(H,22,24)
PDB

UniProtKB/SwissProt

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UniChem
n/an/a 73n/an/an/an/an/an/a


TBA

Assay Description
Active Moz protein was expressed as N-terminal fusion protein with a His6 tag in BL21 E. coli cells. Protein purification was performed via nickel-im...


Citation and Details
More data for this
Ligand-Target Pair
Histone acetyltransferase KAT6A


(Homo sapiens)
BDBM50527336
PNG
(CHEMBL4474246 | US10829446, Compound 143)
Show SMILES CCOc1cc(C)c(F)c(c1)C(=O)NNS(=O)(=O)c1ccccc1F
Show InChI InChI=1S/C16H16F2N2O4S/c1-3-24-11-8-10(2)15(18)12(9-11)16(21)19-20-25(22,23)14-7-5-4-6-13(14)17/h4-9,20H,3H2,1-2H3,(H,19,21)
PDB

UniProtKB/SwissProt

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UniChem
n/an/a 74n/an/an/an/an/an/a


TBA

Assay Description
Active Moz protein was expressed as N-terminal fusion protein with a His6 tag in BL21 E. coli cells. Protein purification was performed via nickel-im...


Citation and Details
More data for this
Ligand-Target Pair
Histone acetyltransferase KAT6A


(Homo sapiens)
BDBM50527288
PNG
(CHEMBL4462062 | US10829446, Compound 44)
Show SMILES Cc1cc(cc(C(=O)NNS(=O)(=O)c2ccccc2)c1F)-c1ccccn1
Show InChI InChI=1S/C19H16FN3O3S/c1-13-11-14(17-9-5-6-10-21-17)12-16(18(13)20)19(24)22-23-27(25,26)15-7-3-2-4-8-15/h2-12,23H,1H3,(H,22,24)
PDB

UniProtKB/SwissProt

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UniChem
n/an/a 75n/an/an/an/an/an/a


TBA

Assay Description
Active Moz protein was expressed as N-terminal fusion protein with a His6 tag in BL21 E. coli cells. Protein purification was performed via nickel-im...


Citation and Details
More data for this
Ligand-Target Pair
Histone acetyltransferase KAT6A


(Homo sapiens)
BDBM50527242
PNG
(CHEMBL4454163 | US10829446, Compound 129)
Show SMILES Fc1ccccc1S(=O)(=O)NNC(=O)c1cccc(c1)-c1cccs1
Show InChI InChI=1S/C17H13FN2O3S2/c18-14-7-1-2-9-16(14)25(22,23)20-19-17(21)13-6-3-5-12(11-13)15-8-4-10-24-15/h1-11,20H,(H,19,21)
PDB

UniProtKB/SwissProt

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UniChem
n/an/a 77n/an/an/an/an/an/a


TBA

Assay Description
Active Moz protein was expressed as N-terminal fusion protein with a His6 tag in BL21 E. coli cells. Protein purification was performed via nickel-im...


Citation and Details
More data for this
Ligand-Target Pair
Histone acetyltransferase KAT6A


(Homo sapiens)
BDBM50527238
PNG
(CHEMBL4539384 | US10829446, Compound 42)
Show SMILES Cc1cc(cc(c1)-c1ccccn1)C(=O)NNS(=O)(=O)c1ccccc1F
Show InChI InChI=1S/C19H16FN3O3S/c1-13-10-14(17-7-4-5-9-21-17)12-15(11-13)19(24)22-23-27(25,26)18-8-3-2-6-16(18)20/h2-12,23H,1H3,(H,22,24)
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n/an/a 77n/an/an/an/an/an/a


TBA

Assay Description
Active Moz protein was expressed as N-terminal fusion protein with a His6 tag in BL21 E. coli cells. Protein purification was performed via nickel-im...


Citation and Details
More data for this
Ligand-Target Pair
Histone acetyltransferase KAT6A


(Homo sapiens)
BDBM50527360
PNG
(CHEMBL4456874 | US10829446, Compound 71)
Show SMILES Cc1ccn(n1)-c1cc(F)cc(c1)C(=O)NNS(=O)(=O)c1ccccc1F
Show InChI InChI=1S/C17H14F2N4O3S/c1-11-6-7-23(21-11)14-9-12(8-13(18)10-14)17(24)20-22-27(25,26)16-5-3-2-4-15(16)19/h2-10,22H,1H3,(H,20,24)
PDB

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n/an/a 78n/an/an/an/an/an/a


TBA

Assay Description
Active Moz protein was expressed as N-terminal fusion protein with a His6 tag in BL21 E. coli cells. Protein purification was performed via nickel-im...


Citation and Details
More data for this
Ligand-Target Pair
Histone acetyltransferase KAT6A


(Homo sapiens)
BDBM50518831
PNG
(CHEMBL4464835 | US10829446, Compound 35)
Show SMILES Fc1c(Cl)cc(cc1C(=O)NNS(=O)(=O)c1ccccc1)-c1ccccc1
Show InChI InChI=1S/C19H14ClFN2O3S/c20-17-12-14(13-7-3-1-4-8-13)11-16(18(17)21)19(24)22-23-27(25,26)15-9-5-2-6-10-15/h1-12,23H,(H,22,24)
PDB

UniProtKB/SwissProt

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UniChem
n/an/a 82n/an/an/an/an/an/a


TBA

Assay Description
Active Moz protein was expressed as N-terminal fusion protein with a His6 tag in BL21 E. coli cells. Protein purification was performed via nickel-im...


Citation and Details
More data for this
Ligand-Target Pair
Histone acetyltransferase KAT6A


(Homo sapiens)
BDBM50527291
PNG
(CHEMBL4556380 | US10829446, Compound 79)
Show SMILES Cc1cnn(c1)-c1cc(C)c(F)c(c1)C(=O)NNS(=O)(=O)c1ccccc1
Show InChI InChI=1S/C18H17FN4O3S/c1-12-10-20-23(11-12)14-8-13(2)17(19)16(9-14)18(24)21-22-27(25,26)15-6-4-3-5-7-15/h3-11,22H,1-2H3,(H,21,24)
PDB

UniProtKB/SwissProt

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UniChem
n/an/a 84n/an/an/an/an/an/a


TBA

Assay Description
Active Moz protein was expressed as N-terminal fusion protein with a His6 tag in BL21 E. coli cells. Protein purification was performed via nickel-im...


Citation and Details
More data for this
Ligand-Target Pair
Histone acetyltransferase KAT6A


(Homo sapiens)
BDBM50527267
PNG
(CHEMBL4588326 | US10829446, Compound 93)
Show SMILES Cc1cc(OCC2CC2)cc(c1)C(=O)NNS(=O)(=O)c1ccccc1F
Show InChI InChI=1S/C18H19FN2O4S/c1-12-8-14(10-15(9-12)25-11-13-6-7-13)18(22)20-21-26(23,24)17-5-3-2-4-16(17)19/h2-5,8-10,13,21H,6-7,11H2,1H3,(H,20,22)
PDB

UniProtKB/SwissProt

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UniChem
n/an/a 84n/an/an/an/an/an/a


TBA

Assay Description
Active Moz protein was expressed as N-terminal fusion protein with a His6 tag in BL21 E. coli cells. Protein purification was performed via nickel-im...


Citation and Details
More data for this
Ligand-Target Pair
Histone acetyltransferase KAT6A


(Homo sapiens)
BDBM50527224
PNG
(CHEMBL4468833 | US10829446, Compound 48)
Show SMILES COc1cc(cc(c1)-c1ccccn1)C(=O)NNS(=O)(=O)c1ccccc1F
Show InChI InChI=1S/C19H16FN3O4S/c1-27-15-11-13(17-7-4-5-9-21-17)10-14(12-15)19(24)22-23-28(25,26)18-8-3-2-6-16(18)20/h2-12,23H,1H3,(H,22,24)
PDB

UniProtKB/SwissProt

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UniChem
n/an/a 85n/an/an/an/an/an/a


TBA

Assay Description
Active Moz protein was expressed as N-terminal fusion protein with a His6 tag in BL21 E. coli cells. Protein purification was performed via nickel-im...


Citation and Details
More data for this
Ligand-Target Pair
Histone acetyltransferase KAT6A


(Homo sapiens)
BDBM50527339
PNG
(CHEMBL4517015 | US10829446, Compound 85)
Show SMILES Cc1ccnn1-c1cc(C)c(F)c(c1)C(=O)NNS(=O)(=O)c1ccccc1
Show InChI InChI=1S/C18H17FN4O3S/c1-12-10-14(23-13(2)8-9-20-23)11-16(17(12)19)18(24)21-22-27(25,26)15-6-4-3-5-7-15/h3-11,22H,1-2H3,(H,21,24)
PDB

UniProtKB/SwissProt

GoogleScholar
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UniChem
n/an/a 87n/an/an/an/an/an/a


TBA

Assay Description
Active Moz protein was expressed as N-terminal fusion protein with a His6 tag in BL21 E. coli cells. Protein purification was performed via nickel-im...


Citation and Details
More data for this
Ligand-Target Pair
Histone acetyltransferase KAT6A


(Homo sapiens)
BDBM50527328
PNG
(CHEMBL4441439 | US10829446, Compound 49)
Show SMILES Cc1cc(cc(c1)-c1ncccn1)C(=O)NNS(=O)(=O)c1ccccc1F
Show InChI InChI=1S/C18H15FN4O3S/c1-12-9-13(17-20-7-4-8-21-17)11-14(10-12)18(24)22-23-27(25,26)16-6-3-2-5-15(16)19/h2-11,23H,1H3,(H,22,24)
PDB

UniProtKB/SwissProt

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UniChem
n/an/a 89n/an/an/an/an/an/a


TBA

Assay Description
Active Moz protein was expressed as N-terminal fusion protein with a His6 tag in BL21 E. coli cells. Protein purification was performed via nickel-im...


Citation and Details
More data for this
Ligand-Target Pair
Histone acetyltransferase KAT6A


(Homo sapiens)
BDBM50527266
PNG
(CHEMBL4590077 | US10829446, Compound 97)
Show SMILES Fc1cc(OCC2CC2)cc(c1)C(=O)NNS(=O)(=O)c1ccccc1F
Show InChI InChI=1S/C17H16F2N2O4S/c18-13-7-12(8-14(9-13)25-10-11-5-6-11)17(22)20-21-26(23,24)16-4-2-1-3-15(16)19/h1-4,7-9,11,21H,5-6,10H2,(H,20,22)
PDB

UniProtKB/SwissProt

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UniChem
n/an/a 91n/an/an/an/an/an/a


TBA

Assay Description
Active Moz protein was expressed as N-terminal fusion protein with a His6 tag in BL21 E. coli cells. Protein purification was performed via nickel-im...


Citation and Details
More data for this
Ligand-Target Pair
Histone acetyltransferase KAT6A


(Homo sapiens)
BDBM50527247
PNG
(CHEMBL4446616 | US10829446, Compound 86)
Show SMILES Cc1ccnn1-c1cc(F)cc(c1)C(=O)NNS(=O)(=O)c1ccccc1F
Show InChI InChI=1S/C17H14F2N4O3S/c1-11-6-7-20-23(11)14-9-12(8-13(18)10-14)17(24)21-22-27(25,26)16-5-3-2-4-15(16)19/h2-10,22H,1H3,(H,21,24)
PDB

UniProtKB/SwissProt

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UniChem
n/an/a 91n/an/an/an/an/an/a


TBA

Assay Description
Active Moz protein was expressed as N-terminal fusion protein with a His6 tag in BL21 E. coli cells. Protein purification was performed via nickel-im...


Citation and Details
More data for this
Ligand-Target Pair
Histone acetyltransferase KAT6A


(Homo sapiens)
BDBM50527317
PNG
(CHEMBL4468268 | US10829446, Compound 123)
Show SMILES CC(C)Oc1cccc(c1)C(=O)NNS(=O)(=O)c1ccccc1F
Show InChI InChI=1S/C16H17FN2O4S/c1-11(2)23-13-7-5-6-12(10-13)16(20)18-19-24(21,22)15-9-4-3-8-14(15)17/h3-11,19H,1-2H3,(H,18,20)
PDB

UniProtKB/SwissProt

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UniChem
n/an/a 93n/an/an/an/an/an/a


TBA

Assay Description
Active Moz protein was expressed as N-terminal fusion protein with a His6 tag in BL21 E. coli cells. Protein purification was performed via nickel-im...


Citation and Details
More data for this
Ligand-Target Pair
Histone acetyltransferase KAT6A


(Homo sapiens)
BDBM50527244
PNG
(CHEMBL4437798 | US10829446, Compound 105)
Show SMILES Fc1ccccc1S(=O)(=O)NNC(=O)c1cc(Cl)cc(c1)-c1ccco1
Show InChI InChI=1S/C17H12ClFN2O4S/c18-13-9-11(15-5-3-7-25-15)8-12(10-13)17(22)20-21-26(23,24)16-6-2-1-4-14(16)19/h1-10,21H,(H,20,22)
PDB

UniProtKB/SwissProt

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PC sid
UniChem
n/an/a 93n/an/an/an/an/an/a


TBA

Assay Description
Active Moz protein was expressed as N-terminal fusion protein with a His6 tag in BL21 E. coli cells. Protein purification was performed via nickel-im...


Citation and Details
More data for this
Ligand-Target Pair
Histone acetyltransferase KAT6A


(Homo sapiens)
BDBM50527268
PNG
(CHEMBL4537104 | US10829446, Compound 96)
Show SMILES CC(C)Oc1cc(F)cc(c1)C(=O)NNS(=O)(=O)c1ccccc1F
Show InChI InChI=1S/C16H16F2N2O4S/c1-10(2)24-13-8-11(7-12(17)9-13)16(21)19-20-25(22,23)15-6-4-3-5-14(15)18/h3-10,20H,1-2H3,(H,19,21)
PDB

UniProtKB/SwissProt

GoogleScholar
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UniChem
n/an/a 93n/an/an/an/an/an/a


TBA

Assay Description
Active Moz protein was expressed as N-terminal fusion protein with a His6 tag in BL21 E. coli cells. Protein purification was performed via nickel-im...


Citation and Details
More data for this
Ligand-Target Pair
Histone acetyltransferase KAT6A


(Homo sapiens)
BDBM50527347
PNG
(CHEMBL4526110 | US10829446, Compound 75)
Show SMILES Cc1cc(cc(c1)-n1cc(F)cn1)C(=O)NNS(=O)(=O)c1ccccc1F
Show InChI InChI=1S/C17H14F2N4O3S/c1-11-6-12(8-14(7-11)23-10-13(18)9-20-23)17(24)21-22-27(25,26)16-5-3-2-4-15(16)19/h2-10,22H,1H3,(H,21,24)
PDB

UniProtKB/SwissProt

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UniChem
n/an/a 94n/an/an/an/an/an/a


TBA

Assay Description
Active Moz protein was expressed as N-terminal fusion protein with a His6 tag in BL21 E. coli cells. Protein purification was performed via nickel-im...


Citation and Details
More data for this
Ligand-Target Pair
Histone acetyltransferase KAT6A


(Homo sapiens)
BDBM50527241
PNG
(CHEMBL4593937 | US10829446, Compound 132)
Show SMILES Fc1ccccc1S(=O)(=O)NNC(=O)c1cc(Cl)cc(c1)-c1cccs1
Show InChI InChI=1S/C17H12ClFN2O3S2/c18-13-9-11(15-5-3-7-25-15)8-12(10-13)17(22)20-21-26(23,24)16-6-2-1-4-14(16)19/h1-10,21H,(H,20,22)
PDB

UniProtKB/SwissProt

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UniChem
n/an/a 96n/an/an/an/an/an/a


TBA

Assay Description
Active Moz protein was expressed as N-terminal fusion protein with a His6 tag in BL21 E. coli cells. Protein purification was performed via nickel-im...


Citation and Details
More data for this
Ligand-Target Pair
Histone acetyltransferase KAT6A


(Homo sapiens)
BDBM50527263
PNG
(CHEMBL4465716 | US10829446, Compound 63)
Show SMILES COc1cc(cc(c1)-n1cccn1)C(=O)NNS(=O)(=O)c1ccccc1F
Show InChI InChI=1S/C17H15FN4O4S/c1-26-14-10-12(9-13(11-14)22-8-4-7-19-22)17(23)20-21-27(24,25)16-6-3-2-5-15(16)18/h2-11,21H,1H3,(H,20,23)
PDB

UniProtKB/SwissProt

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UniChem
n/an/a 97n/an/an/an/an/an/a


TBA

Assay Description
Active Moz protein was expressed as N-terminal fusion protein with a His6 tag in BL21 E. coli cells. Protein purification was performed via nickel-im...


Citation and Details
More data for this
Ligand-Target Pair
Histone acetyltransferase KAT6A


(Homo sapiens)
BDBM50518833
PNG
(CHEMBL4528993 | US10829446, Compound 45)
Show SMILES Fc1cc(cc(c1)-c1ccccn1)C(=O)NNS(=O)(=O)c1ccccc1
Show InChI InChI=1S/C18H14FN3O3S/c19-15-11-13(17-8-4-5-9-20-17)10-14(12-15)18(23)21-22-26(24,25)16-6-2-1-3-7-16/h1-12,22H,(H,21,23)
PDB

UniProtKB/SwissProt

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UniChem
n/an/a 97n/an/an/an/an/an/a


TBA

Assay Description
Active Moz protein was expressed as N-terminal fusion protein with a His6 tag in BL21 E. coli cells. Protein purification was performed via nickel-im...


Citation and Details
More data for this
Ligand-Target Pair
Histone acetyltransferase KAT6A


(Homo sapiens)
BDBM50527352
PNG
(CHEMBL4476346 | US10829446, Compound 61)
Show SMILES Fc1ccc(cc1C(=O)NNS(=O)(=O)c1ccccc1)-n1cccn1
Show InChI InChI=1S/C16H13FN4O3S/c17-15-8-7-12(21-10-4-9-18-21)11-14(15)16(22)19-20-25(23,24)13-5-2-1-3-6-13/h1-11,20H,(H,19,22)
PDB

UniProtKB/SwissProt

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UniChem
n/an/a 97n/an/an/an/an/an/a


TBA

Assay Description
Active Moz protein was expressed as N-terminal fusion protein with a His6 tag in BL21 E. coli cells. Protein purification was performed via nickel-im...


Citation and Details
More data for this
Ligand-Target Pair
Histone acetyltransferase KAT6A


(Homo sapiens)
BDBM50527358
PNG
(CHEMBL4572653 | US10829446, Compound 135)
Show SMILES Fc1ccccc1S(=O)(=O)NNC(=O)c1cccc(c1)-c1ccco1
Show InChI InChI=1S/C17H13FN2O4S/c18-14-7-1-2-9-16(14)25(22,23)20-19-17(21)13-6-3-5-12(11-13)15-8-4-10-24-15/h1-11,20H,(H,19,21)
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UniProtKB/SwissProt

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UniChem
n/an/a 98n/an/an/an/an/an/a


TBA

Assay Description
Active Moz protein was expressed as N-terminal fusion protein with a His6 tag in BL21 E. coli cells. Protein purification was performed via nickel-im...


Citation and Details
More data for this
Ligand-Target Pair
Histone acetyltransferase KAT6A


(Homo sapiens)
BDBM50527382
PNG
(CHEMBL4518462 | US10829446, Compound 145)
Show SMILES Cc1cc(OCC=C)cc(c1)C(=O)NNS(=O)(=O)c1ccccc1F
Show InChI InChI=1S/C17H17FN2O4S/c1-3-8-24-14-10-12(2)9-13(11-14)17(21)19-20-25(22,23)16-7-5-4-6-15(16)18/h3-7,9-11,20H,1,8H2,2H3,(H,19,21)
PDB

UniProtKB/SwissProt

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UniChem
n/an/a 100n/an/an/an/an/an/a


TBA

Assay Description
Active Moz protein was expressed as N-terminal fusion protein with a His6 tag in BL21 E. coli cells. Protein purification was performed via nickel-im...


Citation and Details
More data for this
Ligand-Target Pair
Histone acetyltransferase KAT6A


(Homo sapiens)
BDBM50527383
PNG
(CHEMBL4581333 | US10829446, Compound 43)
Show SMILES Fc1ccc(cc1C(=O)NNS(=O)(=O)c1ccccc1)-c1ccccn1
Show InChI InChI=1S/C18H14FN3O3S/c19-16-10-9-13(17-8-4-5-11-20-17)12-15(16)18(23)21-22-26(24,25)14-6-2-1-3-7-14/h1-12,22H,(H,21,23)
PDB

UniProtKB/SwissProt

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UniChem
n/an/a 100n/an/an/an/an/an/a


TBA

Assay Description
Active Moz protein was expressed as N-terminal fusion protein with a His6 tag in BL21 E. coli cells. Protein purification was performed via nickel-im...


Citation and Details
More data for this
Ligand-Target Pair
Histone acetyltransferase KAT6A


(Homo sapiens)
BDBM50527299
PNG
(CHEMBL4580493 | US10829446, Compound 104)
Show SMILES Clc1cc(cc(c1)-c1ccco1)C(=O)NNS(=O)(=O)c1ccccc1
Show InChI InChI=1S/C17H13ClN2O4S/c18-14-10-12(16-7-4-8-24-16)9-13(11-14)17(21)19-20-25(22,23)15-5-2-1-3-6-15/h1-11,20H,(H,19,21)
PDB

UniProtKB/SwissProt

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UniChem
n/an/a 106n/an/an/an/an/an/a


TBA

Assay Description
Active Moz protein was expressed as N-terminal fusion protein with a His6 tag in BL21 E. coli cells. Protein purification was performed via nickel-im...


Citation and Details
More data for this
Ligand-Target Pair
Histone acetyltransferase KAT6A


(Homo sapiens)
BDBM50527349
PNG
(CHEMBL4569652 | US10829446, Compound 92)
Show SMILES CCOc1cc(F)cc(c1)C(=O)NNS(=O)(=O)c1ccccc1F
Show InChI InChI=1S/C15H14F2N2O4S/c1-2-23-12-8-10(7-11(16)9-12)15(20)18-19-24(21,22)14-6-4-3-5-13(14)17/h3-9,19H,2H2,1H3,(H,18,20)
PDB

UniProtKB/SwissProt

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UniChem
n/an/a 106n/an/an/an/an/an/a


TBA

Assay Description
Active Moz protein was expressed as N-terminal fusion protein with a His6 tag in BL21 E. coli cells. Protein purification was performed via nickel-im...


Citation and Details
More data for this
Ligand-Target Pair
Histone acetyltransferase KAT6A


(Homo sapiens)
BDBM50527357
PNG
(CHEMBL4463739 | US10829446, Compound 103)
Show SMILES COc1cc(cc(c1)-c1ccco1)C(=O)NNS(=O)(=O)c1ccccc1F
Show InChI InChI=1S/C18H15FN2O5S/c1-25-14-10-12(16-6-4-8-26-16)9-13(11-14)18(22)20-21-27(23,24)17-7-3-2-5-15(17)19/h2-11,21H,1H3,(H,20,22)
PDB

UniProtKB/SwissProt

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UniChem
n/an/a 109n/an/an/an/an/an/a


TBA

Assay Description
Active Moz protein was expressed as N-terminal fusion protein with a His6 tag in BL21 E. coli cells. Protein purification was performed via nickel-im...


Citation and Details
More data for this
Ligand-Target Pair
Histone acetyltransferase KAT6A


(Homo sapiens)
BDBM471848
PNG
(US10829446, Compound 90)
Show SMILES Fc1ccccc1S(=O)(=O)NNC(=O)c1cccc(OCC2CC2)c1
Show InChI InChI=1S/C17H17FN2O4S/c18-15-6-1-2-7-16(15)25(22,23)20-19-17(21)13-4-3-5-14(10-13)24-11-12-8-9-12/h1-7,10,12,20H,8-9,11H2,(H,19,21)
PDB

UniProtKB/SwissProt

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UniChem
n/an/a 116n/an/an/an/an/an/a


TBA

Assay Description
Active Moz protein was expressed as N-terminal fusion protein with a His6 tag in BL21 E. coli cells. Protein purification was performed via nickel-im...


Citation and Details
More data for this
Ligand-Target Pair
Histone acetyltransferase KAT6A


(Homo sapiens)
BDBM50527350
PNG
(CHEMBL4578978 | US10829446, Compound 121)
Show SMILES CCCOc1cccc(c1)C(=O)NNS(=O)(=O)c1ccccc1F
Show InChI InChI=1S/C16H17FN2O4S/c1-2-10-23-13-7-5-6-12(11-13)16(20)18-19-24(21,22)15-9-4-3-8-14(15)17/h3-9,11,19H,2,10H2,1H3,(H,18,20)
PDB

UniProtKB/SwissProt

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UniChem
n/an/a 117n/an/an/an/an/an/a


TBA

Assay Description
Active Moz protein was expressed as N-terminal fusion protein with a His6 tag in BL21 E. coli cells. Protein purification was performed via nickel-im...


Citation and Details
More data for this
Ligand-Target Pair
Histone acetyltransferase KAT6A


(Homo sapiens)
BDBM50527371
PNG
(CHEMBL4475866 | US10829446, Compound 76)
Show SMILES Cc1cc(cc(C(=O)NNS(=O)(=O)c2ccccc2)c1F)-n1cc(F)cn1
Show InChI InChI=1S/C17H14F2N4O3S/c1-11-7-13(23-10-12(18)9-20-23)8-15(16(11)19)17(24)21-22-27(25,26)14-5-3-2-4-6-14/h2-10,22H,1H3,(H,21,24)
PDB

UniProtKB/SwissProt

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UniChem
n/an/a 119n/an/an/an/an/an/a


TBA

Assay Description
Active Moz protein was expressed as N-terminal fusion protein with a His6 tag in BL21 E. coli cells. Protein purification was performed via nickel-im...


Citation and Details
More data for this
Ligand-Target Pair
Histone acetyltransferase KAT6A


(Homo sapiens)
BDBM50527251
PNG
(CHEMBL4588945 | US10829446, Compound 66)
Show SMILES Cc1ccn(n1)-c1cccc(c1)C(=O)NNS(=O)(=O)c1ccccc1F
Show InChI InChI=1S/C17H15FN4O3S/c1-12-9-10-22(20-12)14-6-4-5-13(11-14)17(23)19-21-26(24,25)16-8-3-2-7-15(16)18/h2-11,21H,1H3,(H,19,23)
PDB

UniProtKB/SwissProt

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UniChem
n/an/a 120n/an/an/an/an/an/a


TBA

Assay Description
Active Moz protein was expressed as N-terminal fusion protein with a His6 tag in BL21 E. coli cells. Protein purification was performed via nickel-im...


Citation and Details
More data for this
Ligand-Target Pair
Histone acetyltransferase KAT6A


(Homo sapiens)
BDBM50527337
PNG
(CHEMBL4525271 | US10829446, Compound 130)
Show SMILES CCCc1cccc(c1)C(=O)NNS(=O)(=O)c1ccccc1F
Show InChI InChI=1S/C16H17FN2O3S/c1-2-6-12-7-5-8-13(11-12)16(20)18-19-23(21,22)15-10-4-3-9-14(15)17/h3-5,7-11,19H,2,6H2,1H3,(H,18,20)
PDB

UniProtKB/SwissProt

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UniChem
n/an/a 120n/an/an/an/an/an/a


TBA

Assay Description
Active Moz protein was expressed as N-terminal fusion protein with a His6 tag in BL21 E. coli cells. Protein purification was performed via nickel-im...


Citation and Details
More data for this
Ligand-Target Pair
Histone acetyltransferase KAT6A


(Homo sapiens)
BDBM50527232
PNG
(CHEMBL4436877 | US10829446, Compound 78)
Show SMILES Cc1cnn(c1)-c1cc(C)cc(c1)C(=O)NNS(=O)(=O)c1ccccc1F
Show InChI InChI=1S/C18H17FN4O3S/c1-12-7-14(9-15(8-12)23-11-13(2)10-20-23)18(24)21-22-27(25,26)17-6-4-3-5-16(17)19/h3-11,22H,1-2H3,(H,21,24)
PDB

UniProtKB/SwissProt

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UniChem
n/an/a 122n/an/an/an/an/an/a


TBA

Assay Description
Active Moz protein was expressed as N-terminal fusion protein with a His6 tag in BL21 E. coli cells. Protein purification was performed via nickel-im...


Citation and Details
More data for this
Ligand-Target Pair
Histone acetyltransferase KAT6A


(Homo sapiens)
BDBM50527228
PNG
(CHEMBL4464519 | US10829446, Compound 5)
Show SMILES Fc1ccccc1S(=O)(=O)NNC(=O)c1cccc(I)c1
Show InChI InChI=1S/C13H10FIN2O3S/c14-11-6-1-2-7-12(11)21(19,20)17-16-13(18)9-4-3-5-10(15)8-9/h1-8,17H,(H,16,18)
PDB

UniProtKB/SwissProt

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UniChem
n/an/a 123n/an/an/an/an/an/a


TBA

Assay Description
Active Moz protein was expressed as N-terminal fusion protein with a His6 tag in BL21 E. coli cells. Protein purification was performed via nickel-im...


Citation and Details
More data for this
Ligand-Target Pair
Histone acetyltransferase KAT6A


(Homo sapiens)
BDBM50527220
PNG
(CHEMBL4451170 | US10829446, Compound 58)
Show SMILES Fc1ccccc1S(=O)(=O)NNC(=O)c1cccc(c1)-n1cccn1
Show InChI InChI=1S/C16H13FN4O3S/c17-14-7-1-2-8-15(14)25(23,24)20-19-16(22)12-5-3-6-13(11-12)21-10-4-9-18-21/h1-11,20H,(H,19,22)
PDB

UniProtKB/SwissProt

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UniChem
n/an/a 123n/an/an/an/an/an/a


TBA

Assay Description
Active Moz protein was expressed as N-terminal fusion protein with a His6 tag in BL21 E. coli cells. Protein purification was performed via nickel-im...


Citation and Details
More data for this
Ligand-Target Pair
Histone acetyltransferase KAT6A


(Homo sapiens)
BDBM50527312
PNG
(CHEMBL4445093 | US10829446, Compound 120)
Show SMILES CCOc1cccc(c1)C(=O)NNS(=O)(=O)c1ccccc1F
Show InChI InChI=1S/C15H15FN2O4S/c1-2-22-12-7-5-6-11(10-12)15(19)17-18-23(20,21)14-9-4-3-8-13(14)16/h3-10,18H,2H2,1H3,(H,17,19)
PDB

UniProtKB/SwissProt

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UniChem
n/an/a 126n/an/an/an/an/an/a


TBA

Assay Description
Active Moz protein was expressed as N-terminal fusion protein with a His6 tag in BL21 E. coli cells. Protein purification was performed via nickel-im...


Citation and Details
More data for this
Ligand-Target Pair
Histone acetyltransferase KAT6A


(Homo sapiens)
BDBM50527385
PNG
(CHEMBL4465155 | US10829446, Compound 57)
Show SMILES Fc1ccccc1S(=O)(=O)NNC(=O)c1cccc(c1)-c1ncccn1
Show InChI InChI=1S/C17H13FN4O3S/c18-14-7-1-2-8-15(14)26(24,25)22-21-17(23)13-6-3-5-12(11-13)16-19-9-4-10-20-16/h1-11,22H,(H,21,23)
PDB

UniProtKB/SwissProt

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UniChem
n/an/a 126n/an/an/an/an/an/a


TBA

Assay Description
Active Moz protein was expressed as N-terminal fusion protein with a His6 tag in BL21 E. coli cells. Protein purification was performed via nickel-im...


Citation and Details
More data for this
Ligand-Target Pair
Histone acetyltransferase KAT6A


(Homo sapiens)
BDBM50527359
PNG
(CHEMBL4441001 | US10829446, Compound 80)
Show SMILES Cc1cnn(c1)-c1cc(F)cc(c1)C(=O)NNS(=O)(=O)c1ccccc1F
Show InChI InChI=1S/C17H14F2N4O3S/c1-11-9-20-23(10-11)14-7-12(6-13(18)8-14)17(24)21-22-27(25,26)16-5-3-2-4-15(16)19/h2-10,22H,1H3,(H,21,24)
PDB

UniProtKB/SwissProt

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UniChem
n/an/a 126n/an/an/an/an/an/a


TBA

Assay Description
Active Moz protein was expressed as N-terminal fusion protein with a His6 tag in BL21 E. coli cells. Protein purification was performed via nickel-im...


Citation and Details
More data for this
Ligand-Target Pair
Histone acetyltransferase KAT6A


(Homo sapiens)
BDBM50527222
PNG
(CHEMBL4467522 | US10829446, Compound 141)
Show SMILES COc1cc(OC(C)C)cc(c1)C(=O)NNS(=O)(=O)c1ccccc1F
Show InChI InChI=1S/C17H19FN2O5S/c1-11(2)25-14-9-12(8-13(10-14)24-3)17(21)19-20-26(22,23)16-7-5-4-6-15(16)18/h4-11,20H,1-3H3,(H,19,21)
PDB

UniProtKB/SwissProt

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UniChem
n/an/a 133n/an/an/an/an/an/a


TBA

Assay Description
Active Moz protein was expressed as N-terminal fusion protein with a His6 tag in BL21 E. coli cells. Protein purification was performed via nickel-im...


Citation and Details
More data for this
Ligand-Target Pair
Histone acetyltransferase KAT6A


(Homo sapiens)
BDBM50527338
PNG
(CHEMBL4475957 | US10829446, Compound 54)
Show SMILES Fc1ccc(cc1C(=O)NNS(=O)(=O)c1ccccc1)-c1ncccn1
Show InChI InChI=1S/C17H13FN4O3S/c18-15-8-7-12(16-19-9-4-10-20-16)11-14(15)17(23)21-22-26(24,25)13-5-2-1-3-6-13/h1-11,22H,(H,21,23)
PDB

UniProtKB/SwissProt

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PC sid
UniChem
n/an/a 137n/an/an/an/an/an/a


TBA

Assay Description
Active Moz protein was expressed as N-terminal fusion protein with a His6 tag in BL21 E. coli cells. Protein purification was performed via nickel-im...


Citation and Details
More data for this
Ligand-Target Pair
Histone acetyltransferase KAT6A


(Homo sapiens)
BDBM50527281
PNG
(CHEMBL4483705 | US10829446, Compound 24)
Show SMILES Fc1ccccc1S(=O)(=O)NNC(=O)c1cccc(c1)-c1ccccc1
Show InChI InChI=1S/C19H15FN2O3S/c20-17-11-4-5-12-18(17)26(24,25)22-21-19(23)16-10-6-9-15(13-16)14-7-2-1-3-8-14/h1-13,22H,(H,21,23)
PDB

UniProtKB/SwissProt

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UniChem
n/an/a 139n/an/an/an/an/an/a


TBA

Assay Description
Active Moz protein was expressed as N-terminal fusion protein with a His6 tag in BL21 E. coli cells. Protein purification was performed via nickel-im...


Citation and Details
More data for this
Ligand-Target Pair
Histone acetyltransferase KAT6A


(Homo sapiens)
BDBM50527245
PNG
(CHEMBL4521125 | US10829446, Compound 89)
Show SMILES Fc1cc(cc(c1)-n1nccn1)C(=O)NNS(=O)(=O)c1ccccc1F
Show InChI InChI=1S/C15H11F2N5O3S/c16-11-7-10(8-12(9-11)22-18-5-6-19-22)15(23)20-21-26(24,25)14-4-2-1-3-13(14)17/h1-9,21H,(H,20,23)
PDB

UniProtKB/SwissProt

GoogleScholar
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PC sid
UniChem
n/an/a 140n/an/an/an/an/an/a


TBA

Assay Description
Active Moz protein was expressed as N-terminal fusion protein with a His6 tag in BL21 E. coli cells. Protein purification was performed via nickel-im...


Citation and Details
More data for this
Ligand-Target Pair
Histone acetyltransferase KAT6A


(Homo sapiens)
BDBM50527381
PNG
(CHEMBL4466823 | US10829446, Compound 41)
Show SMILES Fc1ccccc1S(=O)(=O)NNC(=O)c1cccc(c1)-c1ccccn1
Show InChI InChI=1S/C18H14FN3O3S/c19-15-8-1-2-10-17(15)26(24,25)22-21-18(23)14-7-5-6-13(12-14)16-9-3-4-11-20-16/h1-12,22H,(H,21,23)
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
n/an/a 142n/an/an/an/an/an/a


TBA

Assay Description
Active Moz protein was expressed as N-terminal fusion protein with a His6 tag in BL21 E. coli cells. Protein purification was performed via nickel-im...


Citation and Details
More data for this
Ligand-Target Pair
Histone acetyltransferase KAT6A


(Homo sapiens)
BDBM50527374
PNG
(CHEMBL4434925 | US10829446, Compound 100)
Show SMILES Fc1cc(cc(c1)-c1ccco1)C(=O)NNS(=O)(=O)c1ccccc1
Show InChI InChI=1S/C17H13FN2O4S/c18-14-10-12(16-7-4-8-24-16)9-13(11-14)17(21)19-20-25(22,23)15-5-2-1-3-6-15/h1-11,20H,(H,19,21)
PDB

UniProtKB/SwissProt

GoogleScholar
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PC sid
UniChem
n/an/a 144n/an/an/an/an/an/a


TBA

Assay Description
Active Moz protein was expressed as N-terminal fusion protein with a His6 tag in BL21 E. coli cells. Protein purification was performed via nickel-im...


Citation and Details
More data for this
Ligand-Target Pair
Histone acetyltransferase KAT6A


(Homo sapiens)
BDBM50527265
PNG
(CHEMBL4559662 | US10829446, Compound 151)
Show SMILES Cc1cc(OC2CC2)cc(c1)C(=O)NNS(=O)(=O)c1ccccc1F
Show InChI InChI=1S/C17H17FN2O4S/c1-11-8-12(10-14(9-11)24-13-6-7-13)17(21)19-20-25(22,23)16-5-3-2-4-15(16)18/h2-5,8-10,13,20H,6-7H2,1H3,(H,19,21)
PDB

UniProtKB/SwissProt

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UniChem
n/an/a 145n/an/an/an/an/an/a


TBA

Assay Description
Active Moz protein was expressed as N-terminal fusion protein with a His6 tag in BL21 E. coli cells. Protein purification was performed via nickel-im...


Citation and Details
More data for this
Ligand-Target Pair
Histone acetyltransferase KAT6A


(Homo sapiens)
BDBM50527327
PNG
(CHEMBL4453559 | US10829446, Compound 55)
Show SMILES COc1cc(cc(c1)-c1ncccn1)C(=O)NNS(=O)(=O)c1ccccc1F
Show InChI InChI=1S/C18H15FN4O4S/c1-27-14-10-12(17-20-7-4-8-21-17)9-13(11-14)18(24)22-23-28(25,26)16-6-3-2-5-15(16)19/h2-11,23H,1H3,(H,22,24)
PDB

UniProtKB/SwissProt

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UniChem
n/an/a 150n/an/an/an/an/an/a


TBA

Assay Description
Active Moz protein was expressed as N-terminal fusion protein with a His6 tag in BL21 E. coli cells. Protein purification was performed via nickel-im...


Citation and Details
More data for this
Ligand-Target Pair
Histone acetyltransferase KAT6A


(Homo sapiens)
BDBM50527306
PNG
(CHEMBL4528681 | US10829446, Compound 140)
Show SMILES Fc1ccc(OCC#C)cc1C(=O)NNS(=O)(=O)c1ccccc1
Show InChI InChI=1S/C16H13FN2O4S/c1-2-10-23-12-8-9-15(17)14(11-12)16(20)18-19-24(21,22)13-6-4-3-5-7-13/h1,3-9,11,19H,10H2,(H,18,20)
PDB

UniProtKB/SwissProt

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UniChem
n/an/a 151n/an/an/an/an/an/a


TBA

Assay Description
Active Moz protein was expressed as N-terminal fusion protein with a His6 tag in BL21 E. coli cells. Protein purification was performed via nickel-im...


Citation and Details
More data for this
Ligand-Target Pair
Histone acetyltransferase KAT6A


(Homo sapiens)
BDBM50527340
PNG
(CHEMBL4456078 | US10829446, Compound 68)
Show SMILES Cc1ccn(n1)-c1ccc(F)c(c1)C(=O)NNS(=O)(=O)c1ccccc1
Show InChI InChI=1S/C17H15FN4O3S/c1-12-9-10-22(20-12)13-7-8-16(18)15(11-13)17(23)19-21-26(24,25)14-5-3-2-4-6-14/h2-11,21H,1H3,(H,19,23)
PDB

UniProtKB/SwissProt

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UniChem
n/an/a 153n/an/an/an/an/an/a


TBA

Assay Description
Active Moz protein was expressed as N-terminal fusion protein with a His6 tag in BL21 E. coli cells. Protein purification was performed via nickel-im...


Citation and Details
More data for this
Ligand-Target Pair
Histone acetyltransferase KAT6A


(Homo sapiens)
BDBM50518827
PNG
(CHEMBL4544946 | US10829446, Compound 8)
Show SMILES O=C(NNS(=O)(=O)c1ccccc1)c1cccc(c1)-c1ccsc1
Show InChI InChI=1S/C17H14N2O3S2/c20-17(18-19-24(21,22)16-7-2-1-3-8-16)14-6-4-5-13(11-14)15-9-10-23-12-15/h1-12,19H,(H,18,20)
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UniProtKB/SwissProt

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UniChem
n/an/a 162n/an/an/an/an/an/a


TBA

Assay Description
Active Moz protein was expressed as N-terminal fusion protein with a His6 tag in BL21 E. coli cells. Protein purification was performed via nickel-im...


Citation and Details
More data for this
Ligand-Target Pair
Histone acetyltransferase KAT6A


(Homo sapiens)
BDBM50527226
PNG
(CHEMBL4585500 | US10829446, Compound 142)
Show SMILES CCOc1cc(OC)cc(c1)C(=O)NNS(=O)(=O)c1ccccc1F
Show InChI InChI=1S/C16H17FN2O5S/c1-3-24-13-9-11(8-12(10-13)23-2)16(20)18-19-25(21,22)15-7-5-4-6-14(15)17/h4-10,19H,3H2,1-2H3,(H,18,20)
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UniProtKB/SwissProt

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n/an/a 167n/an/an/an/an/an/a


TBA

Assay Description
Active Moz protein was expressed as N-terminal fusion protein with a His6 tag in BL21 E. coli cells. Protein purification was performed via nickel-im...


Citation and Details
More data for this
Ligand-Target Pair
Histone acetyltransferase KAT6A


(Homo sapiens)
BDBM50527279
PNG
(CHEMBL4578485 | US10829446, Compound 126)
Show SMILES CC(C)COc1cccc(c1)C(=O)NNS(=O)(=O)c1ccccc1F
Show InChI InChI=1S/C17H19FN2O4S/c1-12(2)11-24-14-7-5-6-13(10-14)17(21)19-20-25(22,23)16-9-4-3-8-15(16)18/h3-10,12,20H,11H2,1-2H3,(H,19,21)
PDB

UniProtKB/SwissProt

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UniChem
n/an/a 176n/an/an/an/an/an/a


TBA

Assay Description
Active Moz protein was expressed as N-terminal fusion protein with a His6 tag in BL21 E. coli cells. Protein purification was performed via nickel-im...


Citation and Details
More data for this
Ligand-Target Pair
Histone acetyltransferase KAT6A


(Homo sapiens)
BDBM50527229
PNG
(CHEMBL4437534 | US10829446, Compound 39)
Show SMILES O=C(NNS(=O)(=O)c1ccccc1)c1cccc(c1)-c1ccccn1
Show InChI InChI=1S/C18H15N3O3S/c22-18(20-21-25(23,24)16-9-2-1-3-10-16)15-8-6-7-14(13-15)17-11-4-5-12-19-17/h1-13,21H,(H,20,22)
PDB

UniProtKB/SwissProt

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UniChem
n/an/a 181n/an/an/an/an/an/a


TBA

Assay Description
Active Moz protein was expressed as N-terminal fusion protein with a His6 tag in BL21 E. coli cells. Protein purification was performed via nickel-im...


Citation and Details
More data for this
Ligand-Target Pair
Histone acetyltransferase KAT6A


(Homo sapiens)
BDBM50527342
PNG
(CHEMBL4465335 | US10829446, Compound 144)
Show SMILES CCOc1ccc(F)c(c1)C(=O)NNS(=O)(=O)c1ccccc1
Show InChI InChI=1S/C15H15FN2O4S/c1-2-22-11-8-9-14(16)13(10-11)15(19)17-18-23(20,21)12-6-4-3-5-7-12/h3-10,18H,2H2,1H3,(H,17,19)
PDB

UniProtKB/SwissProt

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UniChem
n/an/a 185n/an/an/an/an/an/a


TBA

Assay Description
Active Moz protein was expressed as N-terminal fusion protein with a His6 tag in BL21 E. coli cells. Protein purification was performed via nickel-im...


Citation and Details
More data for this
Ligand-Target Pair
Histone acetyltransferase KAT6A


(Homo sapiens)
BDBM50518791
PNG
(CHEMBL4520147 | US10829446, Compound 4)
Show SMILES Cc1cccc(C(=O)NNS(=O)(=O)c2ccc3ccccc3c2)c1F
Show InChI InChI=1S/C18H15FN2O3S/c1-12-5-4-8-16(17(12)19)18(22)20-21-25(23,24)15-10-9-13-6-2-3-7-14(13)11-15/h2-11,21H,1H3,(H,20,22)
PDB

UniProtKB/SwissProt

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UniChem
n/an/a 195n/an/an/an/an/an/a


TBA

Assay Description
Active Moz protein was expressed as N-terminal fusion protein with a His6 tag in BL21 E. coli cells. Protein purification was performed via nickel-im...


Citation and Details
More data for this
Ligand-Target Pair
Histone acetyltransferase KAT6A


(Homo sapiens)
BDBM50527249
PNG
(CHEMBL4532593 | US10829446, Compound 70)
Show SMILES COc1cc(cc(c1)-n1ccc(C)n1)C(=O)NNS(=O)(=O)c1ccccc1F
Show InChI InChI=1S/C18H17FN4O4S/c1-12-7-8-23(21-12)14-9-13(10-15(11-14)27-2)18(24)20-22-28(25,26)17-6-4-3-5-16(17)19/h3-11,22H,1-2H3,(H,20,24)
PDB

UniProtKB/SwissProt

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UniChem
n/an/a 203n/an/an/an/an/an/a


TBA

Assay Description
Active Moz protein was expressed as N-terminal fusion protein with a His6 tag in BL21 E. coli cells. Protein purification was performed via nickel-im...


Citation and Details
More data for this
Ligand-Target Pair
Histone acetyltransferase KAT6A


(Homo sapiens)
BDBM50527292
PNG
(CHEMBL4463475 | US10829446, Compound 82)
Show SMILES Cc1cnn(c1)-c1ccc(F)c(c1)C(=O)NNS(=O)(=O)c1ccccc1
Show InChI InChI=1S/C17H15FN4O3S/c1-12-10-19-22(11-12)13-7-8-16(18)15(9-13)17(23)20-21-26(24,25)14-5-3-2-4-6-14/h2-11,21H,1H3,(H,20,23)
PDB

UniProtKB/SwissProt

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UniChem
n/an/a 221n/an/an/an/an/an/a


TBA

Assay Description
Active Moz protein was expressed as N-terminal fusion protein with a His6 tag in BL21 E. coli cells. Protein purification was performed via nickel-im...


Citation and Details
More data for this
Ligand-Target Pair
Histone acetyltransferase KAT6A


(Homo sapiens)
BDBM50527287
PNG
(CHEMBL4455764 | US10829446, Compound 50)
Show SMILES Cc1cc(cc(c1)-c1ncccn1)C(=O)NNS(=O)(=O)c1ccccc1
Show InChI InChI=1S/C18H16N4O3S/c1-13-10-14(17-19-8-5-9-20-17)12-15(11-13)18(23)21-22-26(24,25)16-6-3-2-4-7-16/h2-12,22H,1H3,(H,21,23)
PDB

UniProtKB/SwissProt

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UniChem
n/an/a 231n/an/an/an/an/an/a


TBA

Assay Description
Active Moz protein was expressed as N-terminal fusion protein with a His6 tag in BL21 E. coli cells. Protein purification was performed via nickel-im...


Citation and Details
More data for this
Ligand-Target Pair
Histone acetyltransferase KAT6A


(Homo sapiens)
BDBM50527278
PNG
(CHEMBL4450945 | US10829446, Compound 131)
Show SMILES Fc1ccccc1S(=O)(=O)NNC(=O)c1cccc(OC2CCCC2)c1
Show InChI InChI=1S/C18H19FN2O4S/c19-16-10-3-4-11-17(16)26(23,24)21-20-18(22)13-6-5-9-15(12-13)25-14-7-1-2-8-14/h3-6,9-12,14,21H,1-2,7-8H2,(H,20,22)
PDB

UniProtKB/SwissProt

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UniChem
n/an/a 244n/an/an/an/an/an/a


TBA

Assay Description
Active Moz protein was expressed as N-terminal fusion protein with a His6 tag in BL21 E. coli cells. Protein purification was performed via nickel-im...


Citation and Details
More data for this
Ligand-Target Pair
Histone acetyltransferase KAT6A


(Homo sapiens)
BDBM50518819
PNG
(CHEMBL4474291 | US10829446, Compound 33)
Show SMILES Fc1c(cccc1-c1ccccc1)C(=O)NNS(=O)(=O)c1ccccc1
Show InChI InChI=1S/C19H15FN2O3S/c20-18-16(14-8-3-1-4-9-14)12-7-13-17(18)19(23)21-22-26(24,25)15-10-5-2-6-11-15/h1-13,22H,(H,21,23)
PDB

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UniChem
n/an/a 270n/an/an/an/an/an/a


TBA

Assay Description
Active Moz protein was expressed as N-terminal fusion protein with a His6 tag in BL21 E. coli cells. Protein purification was performed via nickel-im...


Citation and Details
More data for this
Ligand-Target Pair
Histone acetyltransferase KAT6A


(Homo sapiens)
BDBM50518858
PNG
(CHEMBL4562274 | US10829446, Compound 2)
Show SMILES O=C(NNS(=O)(=O)c1ccccc1)c1cccc(c1)-c1ccccc1
Show InChI InChI=1S/C19H16N2O3S/c22-19(20-21-25(23,24)18-12-5-2-6-13-18)17-11-7-10-16(14-17)15-8-3-1-4-9-15/h1-14,21H,(H,20,22)
PDB

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n/an/a 287n/an/an/an/an/an/a


TBA

Assay Description
Active Moz protein was expressed as N-terminal fusion protein with a His6 tag in BL21 E. coli cells. Protein purification was performed via nickel-im...


Citation and Details
More data for this
Ligand-Target Pair
Histone acetyltransferase KAT6A


(Homo sapiens)
BDBM50527248
PNG
(CHEMBL4549881 | US10829446, Compound 77)
Show SMILES Cc1cnn(c1)-c1cccc(c1)C(=O)NNS(=O)(=O)c1ccccc1F
Show InChI InChI=1S/C17H15FN4O3S/c1-12-10-19-22(11-12)14-6-4-5-13(9-14)17(23)20-21-26(24,25)16-8-3-2-7-15(16)18/h2-11,21H,1H3,(H,20,23)
PDB

UniProtKB/SwissProt

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UniChem
n/an/a 303n/an/an/an/an/an/a


TBA

Assay Description
Active Moz protein was expressed as N-terminal fusion protein with a His6 tag in BL21 E. coli cells. Protein purification was performed via nickel-im...


Citation and Details
More data for this
Ligand-Target Pair
Histone acetyltransferase KAT6A


(Homo sapiens)
BDBM50527252
PNG
(CHEMBL4437810 | US10829446, Compound 83)
Show SMILES Cc1cc(C)n(n1)-c1cccc(c1)C(=O)NNS(=O)(=O)c1ccccc1F
Show InChI InChI=1S/C18H17FN4O3S/c1-12-10-13(2)23(21-12)15-7-5-6-14(11-15)18(24)20-22-27(25,26)17-9-4-3-8-16(17)19/h3-11,22H,1-2H3,(H,20,24)
PDB

UniProtKB/SwissProt

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UniChem
n/an/a 331n/an/an/an/an/an/a


TBA

Assay Description
Active Moz protein was expressed as N-terminal fusion protein with a His6 tag in BL21 E. coli cells. Protein purification was performed via nickel-im...


Citation and Details
More data for this
Ligand-Target Pair
Histone acetyltransferase KAT6A


(Homo sapiens)
BDBM50527283
PNG
(CHEMBL4590691 | US10829446, Compound 20)
Show SMILES Cc1cccc(c1)C(=O)NNS(=O)(=O)c1ccccc1F
Show InChI InChI=1S/C14H13FN2O3S/c1-10-5-4-6-11(9-10)14(18)16-17-21(19,20)13-8-3-2-7-12(13)15/h2-9,17H,1H3,(H,16,18)
PDB

UniProtKB/SwissProt

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UniChem
n/an/a 378n/an/an/an/an/an/a


TBA

Assay Description
Active Moz protein was expressed as N-terminal fusion protein with a His6 tag in BL21 E. coli cells. Protein purification was performed via nickel-im...


Citation and Details
More data for this
Ligand-Target Pair
Histone acetyltransferase KAT6A


(Homo sapiens)
BDBM50527289
PNG
(CHEMBL4448443 | US10829446, Compound 47)
Show SMILES COc1cc(cc(c1)-c1ccccn1)C(=O)NNS(=O)(=O)c1ccccc1
Show InChI InChI=1S/C19H17N3O4S/c1-26-16-12-14(18-9-5-6-10-20-18)11-15(13-16)19(23)21-22-27(24,25)17-7-3-2-4-8-17/h2-13,22H,1H3,(H,21,23)
PDB

UniProtKB/SwissProt

GoogleScholar
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UniChem
n/an/a 393n/an/an/an/an/an/a


TBA

Assay Description
Active Moz protein was expressed as N-terminal fusion protein with a His6 tag in BL21 E. coli cells. Protein purification was performed via nickel-im...


Citation and Details
More data for this
Ligand-Target Pair
Histone acetyltransferase KAT6A


(Homo sapiens)
BDBM50527332
PNG
(CHEMBL4475994 | US10829446, Compound 23)
Show SMILES O=C(NNS(=O)(=O)c1ccccc1)c1cccc(OC2CCCC2)c1
Show InChI InChI=1S/C18H20N2O4S/c21-18(19-20-25(22,23)17-11-2-1-3-12-17)14-7-6-10-16(13-14)24-15-8-4-5-9-15/h1-3,6-7,10-13,15,20H,4-5,8-9H2,(H,19,21)
PDB

UniProtKB/SwissProt

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UniChem
n/an/a 406n/an/an/an/an/an/a


TBA

Assay Description
Active Moz protein was expressed as N-terminal fusion protein with a His6 tag in BL21 E. coli cells. Protein purification was performed via nickel-im...


Citation and Details
More data for this
Ligand-Target Pair
Histone acetyltransferase KAT6A


(Homo sapiens)
BDBM50527233
PNG
(CHEMBL4439337 | US10829446, Compound 73)
Show SMILES Fc1cnn(c1)-c1cccc(c1)C(=O)NNS(=O)(=O)c1ccccc1F
Show InChI InChI=1S/C16H12F2N4O3S/c17-12-9-19-22(10-12)13-5-3-4-11(8-13)16(23)20-21-26(24,25)15-7-2-1-6-14(15)18/h1-10,21H,(H,20,23)
PDB

UniProtKB/SwissProt

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UniChem
n/an/a 411n/an/an/an/an/an/a


TBA

Assay Description
Active Moz protein was expressed as N-terminal fusion protein with a His6 tag in BL21 E. coli cells. Protein purification was performed via nickel-im...


Citation and Details
More data for this
Ligand-Target Pair
Histone acetyltransferase KAT6A


(Homo sapiens)
BDBM50527305
PNG
(CHEMBL4592414 | US10829446, Compound 112)
Show SMILES CCCOc1cc(F)cc(c1)C(=O)NNS(=O)(=O)c1ccccc1
Show InChI InChI=1S/C16H17FN2O4S/c1-2-8-23-14-10-12(9-13(17)11-14)16(20)18-19-24(21,22)15-6-4-3-5-7-15/h3-7,9-11,19H,2,8H2,1H3,(H,18,20)
PDB

UniProtKB/SwissProt

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UniChem
n/an/a 422n/an/an/an/an/an/a


TBA

Assay Description
Active Moz protein was expressed as N-terminal fusion protein with a His6 tag in BL21 E. coli cells. Protein purification was performed via nickel-im...


Citation and Details
More data for this
Ligand-Target Pair
Histone acetyltransferase KAT6A


(Homo sapiens)
BDBM50527294
PNG
(CHEMBL4451724 | US10829446, Compound 72)
Show SMILES Cc1ccn(n1)-c1cc(F)cc(c1)C(=O)NNS(=O)(=O)c1ccccc1
Show InChI InChI=1S/C17H15FN4O3S/c1-12-7-8-22(20-12)15-10-13(9-14(18)11-15)17(23)19-21-26(24,25)16-5-3-2-4-6-16/h2-11,21H,1H3,(H,19,23)
PDB

UniProtKB/SwissProt

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PC cid
PC sid
UniChem
n/an/a 426n/an/an/an/an/an/a


TBA

Assay Description
Active Moz protein was expressed as N-terminal fusion protein with a His6 tag in BL21 E. coli cells. Protein purification was performed via nickel-im...


Citation and Details
More data for this
Ligand-Target Pair
Histone acetyltransferase KAT6A


(Homo sapiens)
BDBM50527309
PNG
(CHEMBL4463902 | US10829446, Compound 18)
Show SMILES CCOc1cccc(c1)C(=O)NNS(=O)(=O)c1ccccc1
Show InChI InChI=1S/C15H16N2O4S/c1-2-21-13-8-6-7-12(11-13)15(18)16-17-22(19,20)14-9-4-3-5-10-14/h3-11,17H,2H2,1H3,(H,16,18)
PDB

UniProtKB/SwissProt

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UniChem
n/an/a 432n/an/an/an/an/an/a


TBA

Assay Description
Active Moz protein was expressed as N-terminal fusion protein with a His6 tag in BL21 E. coli cells. Protein purification was performed via nickel-im...


Citation and Details
More data for this
Ligand-Target Pair
Histone acetyltransferase KAT6A


(Homo sapiens)
BDBM50527331
PNG
(CHEMBL4522271 | US10829446, Compound 125)
Show SMILES CCCCOc1cccc(c1)C(=O)NNS(=O)(=O)c1ccccc1F
Show InChI InChI=1S/C17H19FN2O4S/c1-2-3-11-24-14-8-6-7-13(12-14)17(21)19-20-25(22,23)16-10-5-4-9-15(16)18/h4-10,12,20H,2-3,11H2,1H3,(H,19,21)
PDB

UniProtKB/SwissProt

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UniChem
n/an/a 437n/an/an/an/an/an/a


TBA

Assay Description
Active Moz protein was expressed as N-terminal fusion protein with a His6 tag in BL21 E. coli cells. Protein purification was performed via nickel-im...


Citation and Details
More data for this
Ligand-Target Pair
Histone acetyltransferase KAT6A


(Homo sapiens)
BDBM50527294
PNG
(CHEMBL4451724 | US10829446, Compound 72)
Show SMILES Cc1ccn(n1)-c1cc(F)cc(c1)C(=O)NNS(=O)(=O)c1ccccc1
Show InChI InChI=1S/C17H15FN4O3S/c1-12-7-8-22(20-12)15-10-13(9-14(18)11-15)17(23)19-21-26(24,25)16-5-3-2-4-6-16/h2-11,21H,1H3,(H,19,23)
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
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UniChem
n/an/a 440n/an/an/an/an/an/a


TBA

Assay Description
Active Moz protein was expressed as N-terminal fusion protein with a His6 tag in BL21 E. coli cells. Protein purification was performed via nickel-im...


Citation and Details
More data for this
Ligand-Target Pair
Histone acetyltransferase KAT6A


(Homo sapiens)
BDBM50527343
PNG
(CHEMBL4460681 | US10829446, Compound 9)
Show SMILES CCCOc1cccc(c1)C(=O)NNS(=O)(=O)c1ccccc1
Show InChI InChI=1S/C16H18N2O4S/c1-2-11-22-14-8-6-7-13(12-14)16(19)17-18-23(20,21)15-9-4-3-5-10-15/h3-10,12,18H,2,11H2,1H3,(H,17,19)
PDB

UniProtKB/SwissProt

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UniChem
n/an/a 449n/an/an/an/an/an/a


TBA

Assay Description
Active Moz protein was expressed as N-terminal fusion protein with a His6 tag in BL21 E. coli cells. Protein purification was performed via nickel-im...


Citation and Details
More data for this
Ligand-Target Pair
Histone acetyltransferase KAT6A


(Homo sapiens)
BDBM50527286
PNG
(CHEMBL4470229 | US10829446, Compound 51)
Show SMILES Fc1cc(cc(c1)-c1ncccn1)C(=O)NNS(=O)(=O)c1ccccc1
Show InChI InChI=1S/C17H13FN4O3S/c18-14-10-12(16-19-7-4-8-20-16)9-13(11-14)17(23)21-22-26(24,25)15-5-2-1-3-6-15/h1-11,22H,(H,21,23)
PDB

UniProtKB/SwissProt

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UniChem
n/an/a 449n/an/an/an/an/an/a


TBA

Assay Description
Active Moz protein was expressed as N-terminal fusion protein with a His6 tag in BL21 E. coli cells. Protein purification was performed via nickel-im...


Citation and Details
More data for this
Ligand-Target Pair
Histone acetyltransferase KAT6A


(Homo sapiens)
BDBM50518828
PNG
(CHEMBL4538005 | US10829446, Compound 14)
Show SMILES O=C(NNS(=O)(=O)c1ccccc1)c1cccc(c1)-c1cccs1
Show InChI InChI=1S/C17H14N2O3S2/c20-17(18-19-24(21,22)15-8-2-1-3-9-15)14-7-4-6-13(12-14)16-10-5-11-23-16/h1-12,19H,(H,18,20)
PDB

UniProtKB/SwissProt

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UniChem
n/an/a 470n/an/an/an/an/an/a


TBA

Assay Description
Active Moz protein was expressed as N-terminal fusion protein with a His6 tag in BL21 E. coli cells. Protein purification was performed via nickel-im...


Citation and Details
More data for this
Ligand-Target Pair
Histone acetyltransferase KAT6A


(Homo sapiens)
BDBM50527318
PNG
(CHEMBL4439103 | US10829446, Compound 11)
Show SMILES CC(C)Oc1cccc(c1)C(=O)NNS(=O)(=O)c1ccccc1
Show InChI InChI=1S/C16H18N2O4S/c1-12(2)22-14-8-6-7-13(11-14)16(19)17-18-23(20,21)15-9-4-3-5-10-15/h3-12,18H,1-2H3,(H,17,19)
PDB

UniProtKB/SwissProt

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UniChem
n/an/a 475n/an/an/an/an/an/a


TBA

Assay Description
Active Moz protein was expressed as N-terminal fusion protein with a His6 tag in BL21 E. coli cells. Protein purification was performed via nickel-im...


Citation and Details
More data for this
Ligand-Target Pair
Histone acetyltransferase KAT6A


(Homo sapiens)
BDBM50527231
PNG
(CHEMBL4593009 | US10829446, Compound 102)
Show SMILES COc1cc(cc(c1)-c1ccco1)C(=O)NNS(=O)(=O)c1ccccc1
Show InChI InChI=1S/C18H16N2O5S/c1-24-15-11-13(17-8-5-9-25-17)10-14(12-15)18(21)19-20-26(22,23)16-6-3-2-4-7-16/h2-12,20H,1H3,(H,19,21)
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UniProtKB/SwissProt

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UniChem
n/an/a 478n/an/an/an/an/an/a


TBA

Assay Description
Active Moz protein was expressed as N-terminal fusion protein with a His6 tag in BL21 E. coli cells. Protein purification was performed via nickel-im...


Citation and Details
More data for this
Ligand-Target Pair
Histone acetyltransferase KAT6A


(Homo sapiens)
BDBM50527356
PNG
(CHEMBL4553520 | US10829446, Compound 118)
Show SMILES Fc1ccccc1S(=O)(=O)NNC(=O)c1cccc(c1)-c1ncon1
Show InChI InChI=1S/C15H11FN4O4S/c16-12-6-1-2-7-13(12)25(22,23)20-18-15(21)11-5-3-4-10(8-11)14-17-9-24-19-14/h1-9,20H,(H,18,21)
PDB

UniProtKB/SwissProt

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UniChem
n/an/a 488n/an/an/an/an/an/a


TBA

Assay Description
Active Moz protein was expressed as N-terminal fusion protein with a His6 tag in BL21 E. coli cells. Protein purification was performed via nickel-im...


Citation and Details
More data for this
Ligand-Target Pair
Histone acetyltransferase KAT6A


(Homo sapiens)
BDBM50518795
PNG
(CHEMBL4582659 | US10829446, Compound 29)
Show SMILES Fc1ccccc1-c1cccc(c1)C(=O)NNS(=O)(=O)c1ccccc1
Show InChI InChI=1S/C19H15FN2O3S/c20-18-12-5-4-11-17(18)14-7-6-8-15(13-14)19(23)21-22-26(24,25)16-9-2-1-3-10-16/h1-13,22H,(H,21,23)
PDB

UniProtKB/SwissProt

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UniChem
n/an/a 548n/an/an/an/an/an/a


TBA

Assay Description
Active Moz protein was expressed as N-terminal fusion protein with a His6 tag in BL21 E. coli cells. Protein purification was performed via nickel-im...


Citation and Details
More data for this
Ligand-Target Pair
Histone acetyltransferase KAT6A


(Homo sapiens)
BDBM50527290
PNG
(CHEMBL4517852 | US10829446, Compound 74)
Show SMILES Cc1cc(cc(c1)-n1cc(F)cn1)C(=O)NNS(=O)(=O)c1ccccc1
Show InChI InChI=1S/C17H15FN4O3S/c1-12-7-13(9-15(8-12)22-11-14(18)10-19-22)17(23)20-21-26(24,25)16-5-3-2-4-6-16/h2-11,21H,1H3,(H,20,23)
PDB

UniProtKB/SwissProt

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UniChem
n/an/a 552n/an/an/an/an/an/a


TBA

Assay Description
Active Moz protein was expressed as N-terminal fusion protein with a His6 tag in BL21 E. coli cells. Protein purification was performed via nickel-im...


Citation and Details
More data for this
Ligand-Target Pair
Histone acetyltransferase KAT6A


(Homo sapiens)
BDBM50527216
PNG
(CHEMBL4569365 | US10829446, Compound 128)
Show SMILES Fc1ccccc1S(=O)(=O)NNC(=O)c1cccc(OC(F)(F)F)c1
Show InChI InChI=1S/C14H10F4N2O4S/c15-11-6-1-2-7-12(11)25(22,23)20-19-13(21)9-4-3-5-10(8-9)24-14(16,17)18/h1-8,20H,(H,19,21)
PDB

UniProtKB/SwissProt

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UniChem
n/an/a 558n/an/an/an/an/an/a


TBA

Assay Description
Active Moz protein was expressed as N-terminal fusion protein with a His6 tag in BL21 E. coli cells. Protein purification was performed via nickel-im...


Citation and Details
More data for this
Ligand-Target Pair
Histone acetyltransferase KAT6A


(Homo sapiens)
BDBM50518855
PNG
(CHEMBL4471104 | US10829446, Compound 40)
Show SMILES O=C(NNS(=O)(=O)c1ccccc1)c1cccc(c1)-n1cccn1
Show InChI InChI=1S/C16H14N4O3S/c21-16(18-19-24(22,23)15-8-2-1-3-9-15)13-6-4-7-14(12-13)20-11-5-10-17-20/h1-12,19H,(H,18,21)
PDB

UniProtKB/SwissProt

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UniChem
n/an/a 635n/an/an/an/an/an/a


TBA

Assay Description
Active Moz protein was expressed as N-terminal fusion protein with a His6 tag in BL21 E. coli cells. Protein purification was performed via nickel-im...


Citation and Details
More data for this
Ligand-Target Pair
Histone acetyltransferase KAT6A


(Homo sapiens)
BDBM50527370
PNG
(CHEMBL4561694 | US10829446, Compound 38)
Show SMILES O=C(NNS(=O)(=O)c1ccccc1)c1cccc(c1)-c1ncccn1
Show InChI InChI=1S/C17H14N4O3S/c22-17(20-21-25(23,24)15-8-2-1-3-9-15)14-7-4-6-13(12-14)16-18-10-5-11-19-16/h1-12,21H,(H,20,22)
PDB

UniProtKB/SwissProt

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PC sid
UniChem
n/an/a 674n/an/an/an/an/an/a


TBA

Assay Description
Active Moz protein was expressed as N-terminal fusion protein with a His6 tag in BL21 E. coli cells. Protein purification was performed via nickel-im...


Citation and Details
More data for this
Ligand-Target Pair
Histone acetyltransferase KAT6A


(Homo sapiens)
BDBM50527282
PNG
(CHEMBL4441536 | US10829446, Compound 127)
Show SMILES CCc1cccc(c1)C(=O)NNS(=O)(=O)c1ccccc1F
Show InChI InChI=1S/C15H15FN2O3S/c1-2-11-6-5-7-12(10-11)15(19)17-18-22(20,21)14-9-4-3-8-13(14)16/h3-10,18H,2H2,1H3,(H,17,19)
PDB

UniProtKB/SwissProt

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PC sid
UniChem
n/an/a 675n/an/an/an/an/an/a


TBA

Assay Description
Active Moz protein was expressed as N-terminal fusion protein with a His6 tag in BL21 E. coli cells. Protein purification was performed via nickel-im...


Citation and Details
More data for this
Ligand-Target Pair
Histone acetyltransferase KAT6A


(Homo sapiens)
BDBM50518823
PNG
(CHEMBL4443846 | US10829446, Compound 30)
Show SMILES Fc1cccc(c1)-c1cccc(c1)C(=O)NNS(=O)(=O)c1ccccc1
Show InChI InChI=1S/C19H15FN2O3S/c20-17-9-5-7-15(13-17)14-6-4-8-16(12-14)19(23)21-22-26(24,25)18-10-2-1-3-11-18/h1-13,22H,(H,21,23)
PDB

UniProtKB/SwissProt

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UniChem
n/an/a 721n/an/an/an/an/an/a


TBA

Assay Description
Active Moz protein was expressed as N-terminal fusion protein with a His6 tag in BL21 E. coli cells. Protein purification was performed via nickel-im...


Citation and Details
More data for this
Ligand-Target Pair
Histone acetyltransferase KAT6A


(Homo sapiens)
BDBM50527372
PNG
(CHEMBL4459368 | US10829446, Compound 81)
Show SMILES Cc1cnn(c1)-c1cc(F)cc(c1)C(=O)NNS(=O)(=O)c1ccccc1
Show InChI InChI=1S/C17H15FN4O3S/c1-12-10-19-22(11-12)15-8-13(7-14(18)9-15)17(23)20-21-26(24,25)16-5-3-2-4-6-16/h2-11,21H,1H3,(H,20,23)
PDB

UniProtKB/SwissProt

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UniChem
n/an/a 748n/an/an/an/an/an/a


TBA

Assay Description
Active Moz protein was expressed as N-terminal fusion protein with a His6 tag in BL21 E. coli cells. Protein purification was performed via nickel-im...


Citation and Details
More data for this
Ligand-Target Pair
Histone acetyltransferase KAT6A


(Homo sapiens)
BDBM471898
PNG
(US10829446, Compound 133)
Show SMILES Fc1ccc(cc1)-c1ccc(F)c(c1)C(=O)NNS(=O)(=O)c1ccccc1F
Show InChI InChI=1S/C19H13F3N2O3S/c20-14-8-5-12(6-9-14)13-7-10-16(21)15(11-13)19(25)23-24-28(26,27)18-4-2-1-3-17(18)22/h1-11,24H,(H,23,25)
PDB

UniProtKB/SwissProt

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UniChem
n/an/a 839n/an/an/an/an/an/a


TBA

Assay Description
Active Moz protein was expressed as N-terminal fusion protein with a His6 tag in BL21 E. coli cells. Protein purification was performed via nickel-im...


Citation and Details
More data for this
Ligand-Target Pair
Histone acetyltransferase KAT6A


(Homo sapiens)
BDBM50527315
PNG
(CHEMBL4566381 | US10829446, Compound 122)
Show SMILES CC(C)c1cccc(c1)C(=O)NNS(=O)(=O)c1ccccc1F
Show InChI InChI=1S/C16H17FN2O3S/c1-11(2)12-6-5-7-13(10-12)16(20)18-19-23(21,22)15-9-4-3-8-14(15)17/h3-11,19H,1-2H3,(H,18,20)
PDB

UniProtKB/SwissProt

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UniChem
n/an/a 966n/an/an/an/an/an/a


TBA

Assay Description
Active Moz protein was expressed as N-terminal fusion protein with a His6 tag in BL21 E. coli cells. Protein purification was performed via nickel-im...


Citation and Details
More data for this
Ligand-Target Pair
Histone acetyltransferase KAT6A


(Homo sapiens)
BDBM50527297
PNG
(CHEMBL4461279 | US10829446, Compound 13)
Show SMILES O=C(NNS(=O)(=O)c1ccccc1)c1cccc(c1)-c1nccs1
Show InChI InChI=1S/C16H13N3O3S2/c20-15(18-19-24(21,22)14-7-2-1-3-8-14)12-5-4-6-13(11-12)16-17-9-10-23-16/h1-11,19H,(H,18,20)
PDB

UniProtKB/SwissProt

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PC sid
UniChem
n/an/a 998n/an/an/an/an/an/a


TBA

Assay Description
Active Moz protein was expressed as N-terminal fusion protein with a His6 tag in BL21 E. coli cells. Protein purification was performed via nickel-im...


Citation and Details
More data for this
Ligand-Target Pair
Histone acetyltransferase KAT6A


(Homo sapiens)
BDBM50527373
PNG
(CHEMBL4469704 | US10829446, Compound 62)
Show SMILES COc1cc(cc(c1)-n1cccn1)C(=O)NNS(=O)(=O)c1ccccc1
Show InChI InChI=1S/C17H16N4O4S/c1-25-15-11-13(10-14(12-15)21-9-5-8-18-21)17(22)19-20-26(23,24)16-6-3-2-4-7-16/h2-12,20H,1H3,(H,19,22)
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
n/an/a 1.17E+3n/an/an/an/an/an/a


TBA

Assay Description
Active Moz protein was expressed as N-terminal fusion protein with a His6 tag in BL21 E. coli cells. Protein purification was performed via nickel-im...


Citation and Details
More data for this
Ligand-Target Pair
Histone acetyltransferase KAT6A


(Homo sapiens)
BDBM50527285
PNG
(CHEMBL4468749 | US10829446, Compound 56)
Show SMILES COc1cc(cc(c1)-c1ncccn1)C(=O)NNS(=O)(=O)c1ccccc1
Show InChI InChI=1S/C18H16N4O4S/c1-26-15-11-13(17-19-8-5-9-20-17)10-14(12-15)18(23)21-22-27(24,25)16-6-3-2-4-7-16/h2-12,22H,1H3,(H,21,23)
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
n/an/a 1.25E+3n/an/an/an/an/an/a


TBA

Assay Description
Active Moz protein was expressed as N-terminal fusion protein with a His6 tag in BL21 E. coli cells. Protein purification was performed via nickel-im...


Citation and Details
More data for this
Ligand-Target Pair
Histone acetyltransferase KAT6A


(Homo sapiens)
BDBM50527387
PNG
(CHEMBL4467591 | US10829446, Compound 16)
Show SMILES CC(C)COc1cccc(c1)C(=O)NNS(=O)(=O)c1ccccc1
Show InChI InChI=1S/C17H20N2O4S/c1-13(2)12-23-15-8-6-7-14(11-15)17(20)18-19-24(21,22)16-9-4-3-5-10-16/h3-11,13,19H,12H2,1-2H3,(H,18,20)
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
n/an/a 1.67E+3n/an/an/an/an/an/a


TBA

Assay Description
Active Moz protein was expressed as N-terminal fusion protein with a His6 tag in BL21 E. coli cells. Protein purification was performed via nickel-im...


Citation and Details
More data for this
Ligand-Target Pair
Histone acetyltransferase KAT6A


(Homo sapiens)
BDBM50518836
PNG
(CHEMBL4568429 | US10829446, Compound 148)
Show SMILES Cc1cccc(c1)C(=O)NNS(=O)(=O)c1ccc2ccccc2c1
Show InChI InChI=1S/C18H16N2O3S/c1-13-5-4-8-16(11-13)18(21)19-20-24(22,23)17-10-9-14-6-2-3-7-15(14)12-17/h2-12,20H,1H3,(H,19,21)
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
n/an/a 1.77E+3n/an/an/an/an/an/a


TBA

Assay Description
Active Moz protein was expressed as N-terminal fusion protein with a His6 tag in BL21 E. coli cells. Protein purification was performed via nickel-im...


Citation and Details
More data for this
Ligand-Target Pair
Histone acetyltransferase KAT6A


(Homo sapiens)
BDBM50527300
PNG
(CHEMBL4545831 | US10829446, Compound 107)
Show SMILES Fc1ccccc1S(=O)(=O)NNC(=O)c1ccnc(c1)-c1ccccc1
Show InChI InChI=1S/C18H14FN3O3S/c19-15-8-4-5-9-17(15)26(24,25)22-21-18(23)14-10-11-20-16(12-14)13-6-2-1-3-7-13/h1-12,22H,(H,21,23)
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
n/an/a 1.92E+3n/an/an/an/an/an/a


TBA

Assay Description
Active Moz protein was expressed as N-terminal fusion protein with a His6 tag in BL21 E. coli cells. Protein purification was performed via nickel-im...


Citation and Details
More data for this
Ligand-Target Pair
Histone acetyltransferase KAT6A


(Homo sapiens)
BDBM471728
PNG
(US10829446, Compound 6)
Show SMILES Ic1cccc(c1)C(=O)NNS(=O)(=O)c1ccccc1
Show InChI InChI=1S/C13H11IN2O3S/c14-11-6-4-5-10(9-11)13(17)15-16-20(18,19)12-7-2-1-3-8-12/h1-9,16H,(H,15,17)
PDB

UniProtKB/SwissProt

GoogleScholar
UniChem
n/an/a 2.04E+3n/an/an/an/an/an/a


TBA

Assay Description
Active Moz protein was expressed as N-terminal fusion protein with a His6 tag in BL21 E. coli cells. Protein purification was performed via nickel-im...


Citation and Details
More data for this
Ligand-Target Pair
Histone acetyltransferase KAT6A


(Homo sapiens)
BDBM50527323
PNG
(CHEMBL4456194 | US10829446, Compound 21)
Show SMILES CCCc1cccc(c1)C(=O)NNS(=O)(=O)c1ccccc1
Show InChI InChI=1S/C16H18N2O3S/c1-2-7-13-8-6-9-14(12-13)16(19)17-18-22(20,21)15-10-4-3-5-11-15/h3-6,8-12,18H,2,7H2,1H3,(H,17,19)
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
n/an/a 2.35E+3n/an/an/an/an/an/a


TBA

Assay Description
Active Moz protein was expressed as N-terminal fusion protein with a His6 tag in BL21 E. coli cells. Protein purification was performed via nickel-im...


Citation and Details
More data for this
Ligand-Target Pair
Histone acetyltransferase KAT6A


(Homo sapiens)
BDBM50527322
PNG
(CHEMBL4470247 | US10829446, Compound 19)
Show SMILES Cc1cccc(c1)C(=O)NNS(=O)(=O)c1ccccc1
Show InChI InChI=1S/C14H14N2O3S/c1-11-6-5-7-12(10-11)14(17)15-16-20(18,19)13-8-3-2-4-9-13/h2-10,16H,1H3,(H,15,17)
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
n/an/a 2.44E+3n/an/an/an/an/an/a


TBA

Assay Description
Active Moz protein was expressed as N-terminal fusion protein with a His6 tag in BL21 E. coli cells. Protein purification was performed via nickel-im...


Citation and Details
More data for this
Ligand-Target Pair
Histone acetyltransferase KAT6A


(Homo sapiens)
BDBM50527324
PNG
(CHEMBL4455968 | US10829446, Compound 110)
Show SMILES Fc1ccccc1S(=O)(=O)NNC(=O)c1cncc(c1)-c1ccccc1
Show InChI InChI=1S/C18H14FN3O3S/c19-16-8-4-5-9-17(16)26(24,25)22-21-18(23)15-10-14(11-20-12-15)13-6-2-1-3-7-13/h1-12,22H,(H,21,23)
PDB

UniProtKB/SwissProt

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PC cid
PC sid
UniChem
n/an/a 2.59E+3n/an/an/an/an/an/a


TBA

Assay Description
Active Moz protein was expressed as N-terminal fusion protein with a His6 tag in BL21 E. coli cells. Protein purification was performed via nickel-im...


Citation and Details
More data for this
Ligand-Target Pair
Histone acetyltransferase KAT6A


(Homo sapiens)
BDBM50518840
PNG
(CHEMBL4582784 | US10829446, Compound 1)
Show SMILES O=C(NNS(=O)(=O)c1ccc2ccccc2c1)c1cccc(c1)-c1ccccc1
Show InChI InChI=1S/C23H18N2O3S/c26-23(21-12-6-11-19(15-21)17-7-2-1-3-8-17)24-25-29(27,28)22-14-13-18-9-4-5-10-20(18)16-22/h1-16,25H,(H,24,26)
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
n/an/a 2.95E+3n/an/an/an/an/an/a


TBA

Assay Description
Active Moz protein was expressed as N-terminal fusion protein with a His6 tag in BL21 E. coli cells. Protein purification was performed via nickel-im...


Citation and Details
More data for this
Ligand-Target Pair
Histone acetyltransferase KAT6A


(Homo sapiens)
BDBM50527319
PNG
(CHEMBL4463977 | US10829446, Compound 15)
Show SMILES CCCCOc1cccc(c1)C(=O)NNS(=O)(=O)c1ccccc1
Show InChI InChI=1S/C17H20N2O4S/c1-2-3-12-23-15-9-7-8-14(13-15)17(20)18-19-24(21,22)16-10-5-4-6-11-16/h4-11,13,19H,2-3,12H2,1H3,(H,18,20)
PDB

UniProtKB/SwissProt

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PC cid
PC sid
UniChem
n/an/a 3.17E+3n/an/an/an/an/an/a


TBA

Assay Description
Active Moz protein was expressed as N-terminal fusion protein with a His6 tag in BL21 E. coli cells. Protein purification was performed via nickel-im...


Citation and Details
More data for this
Ligand-Target Pair
Histone acetyltransferase KAT6A


(Homo sapiens)
BDBM50518850
PNG
(CHEMBL4483508 | US10829446, Compound 28)
Show SMILES COc1cccc(c1)-c1cccc(c1)C(=O)NNS(=O)(=O)c1ccccc1
Show InChI InChI=1S/C20H18N2O4S/c1-26-18-10-6-8-16(14-18)15-7-5-9-17(13-15)20(23)21-22-27(24,25)19-11-3-2-4-12-19/h2-14,22H,1H3,(H,21,23)
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
n/an/a 3.22E+3n/an/an/an/an/an/a


TBA

Assay Description
Active Moz protein was expressed as N-terminal fusion protein with a His6 tag in BL21 E. coli cells. Protein purification was performed via nickel-im...


Citation and Details
More data for this
Ligand-Target Pair
Histone acetyltransferase KAT6A


(Homo sapiens)
BDBM50527388
PNG
(CHEMBL4529837 | US10829446, Compound 17)
Show SMILES CCc1cccc(c1)C(=O)NNS(=O)(=O)c1ccccc1
Show InChI InChI=1S/C15H16N2O3S/c1-2-12-7-6-8-13(11-12)15(18)16-17-21(19,20)14-9-4-3-5-10-14/h3-11,17H,2H2,1H3,(H,16,18)
PDB

UniProtKB/SwissProt

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UniChem
n/an/a 3.79E+3n/an/an/an/an/an/a


TBA

Assay Description
Active Moz protein was expressed as N-terminal fusion protein with a His6 tag in BL21 E. coli cells. Protein purification was performed via nickel-im...


Citation and Details
More data for this
Ligand-Target Pair
Histone acetyltransferase KAT6A


(Homo sapiens)
BDBM50518824
PNG
(CHEMBL4445689 | US10829446, Compound 25)
Show SMILES Fc1ccc(cc1)-c1cccc(c1)C(=O)NNS(=O)(=O)c1ccccc1
Show InChI InChI=1S/C19H15FN2O3S/c20-17-11-9-14(10-12-17)15-5-4-6-16(13-15)19(23)21-22-26(24,25)18-7-2-1-3-8-18/h1-13,22H,(H,21,23)
PDB

UniProtKB/SwissProt

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UniChem
n/an/a 3.83E+3n/an/an/an/an/an/a


TBA

Assay Description
Active Moz protein was expressed as N-terminal fusion protein with a His6 tag in BL21 E. coli cells. Protein purification was performed via nickel-im...


Citation and Details
More data for this
Ligand-Target Pair
Histone acetyltransferase KAT6A


(Homo sapiens)
BDBM50527389
PNG
(CHEMBL4472421 | US10829446, Compound 117)
Show SMILES Fc1ccccc1S(=O)(=O)NNC(=O)c1cccc(n1)-c1ccccc1
Show InChI InChI=1S/C18H14FN3O3S/c19-14-9-4-5-12-17(14)26(24,25)22-21-18(23)16-11-6-10-15(20-16)13-7-2-1-3-8-13/h1-12,22H,(H,21,23)
PDB

UniProtKB/SwissProt

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UniChem
n/an/a 4.55E+3n/an/an/an/an/an/a


TBA

Assay Description
Active Moz protein was expressed as N-terminal fusion protein with a His6 tag in BL21 E. coli cells. Protein purification was performed via nickel-im...


Citation and Details
More data for this
Ligand-Target Pair
Histone acetyltransferase KAT6A


(Homo sapiens)
BDBM50527239
PNG
(CHEMBL4539968 | US10829446, Compound 115)
Show SMILES Fc1ccccc1S(=O)(=O)NNC(=O)c1cccc(c1)-c1nnco1
Show InChI InChI=1S/C15H11FN4O4S/c16-12-6-1-2-7-13(12)25(22,23)20-18-14(21)10-4-3-5-11(8-10)15-19-17-9-24-15/h1-9,20H,(H,18,21)
PDB

UniProtKB/SwissProt

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UniChem
n/an/a 4.62E+3n/an/an/an/an/an/a


TBA

Assay Description
Active Moz protein was expressed as N-terminal fusion protein with a His6 tag in BL21 E. coli cells. Protein purification was performed via nickel-im...


Citation and Details
More data for this
Ligand-Target Pair
Histone acetyltransferase KAT6A


(Homo sapiens)
BDBM50527217
PNG
(CHEMBL4585031 | US10829446, Compound 10)
Show SMILES CC(C)c1cccc(c1)C(=O)NNS(=O)(=O)c1ccccc1
Show InChI InChI=1S/C16H18N2O3S/c1-12(2)13-7-6-8-14(11-13)16(19)17-18-22(20,21)15-9-4-3-5-10-15/h3-12,18H,1-2H3,(H,17,19)
PDB

UniProtKB/SwissProt

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UniChem
n/an/a 6.87E+3n/an/an/an/an/an/a


TBA

Assay Description
Active Moz protein was expressed as N-terminal fusion protein with a His6 tag in BL21 E. coli cells. Protein purification was performed via nickel-im...


Citation and Details
More data for this
Ligand-Target Pair
Histone acetyltransferase KAT6A


(Homo sapiens)
BDBM50527378
PNG
(CHEMBL2142778 | US10829446, Compound 149)
Show SMILES COc1cccc(c1)C(=O)NNS(=O)(=O)c1ccccc1
Show InChI InChI=1S/C14H14N2O4S/c1-20-12-7-5-6-11(10-12)14(17)15-16-21(18,19)13-8-3-2-4-9-13/h2-10,16H,1H3,(H,15,17)
PDB

UniProtKB/SwissProt

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UniChem
n/an/a 7.07E+3n/an/an/an/an/an/a


TBA

Assay Description
Active Moz protein was expressed as N-terminal fusion protein with a His6 tag in BL21 E. coli cells. Protein purification was performed via nickel-im...


Citation and Details
More data for this
Ligand-Target Pair
Histone acetyltransferase KAT6A


(Homo sapiens)
BDBM471729
PNG
(US10829446, Compound 7)
Show SMILES O=C(NNS(=O)(=O)c1ccccc1)c1cccc(c1)-c1cc[nH]n1
Show InChI InChI=1S/C16H14N4O3S/c21-16(19-20-24(22,23)14-7-2-1-3-8-14)13-6-4-5-12(11-13)15-9-10-17-18-15/h1-11,20H,(H,17,18)(H,19,21)
PDB

UniProtKB/SwissProt

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UniChem
n/an/a 7.44E+3n/an/an/an/an/an/a


TBA

Assay Description
Active Moz protein was expressed as N-terminal fusion protein with a His6 tag in BL21 E. coli cells. Protein purification was performed via nickel-im...


Citation and Details
More data for this
Ligand-Target Pair
Histone acetyltransferase KAT6A


(Homo sapiens)
BDBM50518837
PNG
(CHEMBL4473757 | US10829446, Compound 3)
Show SMILES CC(C)c1cccc(c1)C(=O)NNS(=O)(=O)c1ccc2ccccc2c1
Show InChI InChI=1S/C20H20N2O3S/c1-14(2)16-8-5-9-18(12-16)20(23)21-22-26(24,25)19-11-10-15-6-3-4-7-17(15)13-19/h3-14,22H,1-2H3,(H,21,23)
PDB

UniProtKB/SwissProt

GoogleScholar
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UniChem
n/an/a 7.80E+3n/an/an/an/an/an/a


TBA

Assay Description
Active Moz protein was expressed as N-terminal fusion protein with a His6 tag in BL21 E. coli cells. Protein purification was performed via nickel-im...


Citation and Details
More data for this
Ligand-Target Pair
Histone acetyltransferase KAT6A


(Homo sapiens)
BDBM50518868
PNG
(CHEMBL4434645 | US10829446, Compound 34)
Show SMILES Clc1ccccc1-c1cccc(c1)C(=O)NNS(=O)(=O)c1ccccc1
Show InChI InChI=1S/C19H15ClN2O3S/c20-18-12-5-4-11-17(18)14-7-6-8-15(13-14)19(23)21-22-26(24,25)16-9-2-1-3-10-16/h1-13,22H,(H,21,23)
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
n/an/a 8.02E+3n/an/an/an/an/an/a


TBA

Assay Description
Active Moz protein was expressed as N-terminal fusion protein with a His6 tag in BL21 E. coli cells. Protein purification was performed via nickel-im...


Citation and Details
More data for this
Ligand-Target Pair
Histone acetyltransferase KAT6A


(Homo sapiens)
BDBM50527321
PNG
(CHEMBL4460686 | US10829446, Compound 22)
Show SMILES FC(F)(F)Oc1cccc(c1)C(=O)NNS(=O)(=O)c1ccccc1
Show InChI InChI=1S/C14H11F3N2O4S/c15-14(16,17)23-11-6-4-5-10(9-11)13(20)18-19-24(21,22)12-7-2-1-3-8-12/h1-9,19H,(H,18,20)
PDB

UniProtKB/SwissProt

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PC sid
UniChem
n/an/a 8.47E+3n/an/an/an/an/an/a


TBA

Assay Description
Active Moz protein was expressed as N-terminal fusion protein with a His6 tag in BL21 E. coli cells. Protein purification was performed via nickel-im...


Citation and Details
More data for this
Ligand-Target Pair
Histone acetyltransferase KAT6A


(Homo sapiens)
BDBM50518856
PNG
(CHEMBL4466290 | US10829446, Compound 31)
Show SMILES O=C(NNS(=O)(=O)c1ccccc1)c1cccc(c1)-c1cccc(c1)C#N
Show InChI InChI=1S/C20H15N3O3S/c21-14-15-6-4-7-16(12-15)17-8-5-9-18(13-17)20(24)22-23-27(25,26)19-10-2-1-3-11-19/h1-13,23H,(H,22,24)
PDB

UniProtKB/SwissProt

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PC cid
PC sid
UniChem
n/an/a 8.55E+3n/an/an/an/an/an/a


TBA

Assay Description
Active Moz protein was expressed as N-terminal fusion protein with a His6 tag in BL21 E. coli cells. Protein purification was performed via nickel-im...


Citation and Details
More data for this
Ligand-Target Pair
Histone acetyltransferase KAT6A


(Homo sapiens)
BDBM50527330
PNG
(CHEMBL4564913 | US10829446, Compound 119)
Show SMILES FC(F)(F)c1cccc(c1)C(=O)NNS(=O)(=O)c1ccccc1
Show InChI InChI=1S/C14H11F3N2O3S/c15-14(16,17)11-6-4-5-10(9-11)13(20)18-19-23(21,22)12-7-2-1-3-8-12/h1-9,19H,(H,18,20)
PDB

UniProtKB/SwissProt

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PC cid
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UniChem
n/an/a 1.05E+4n/an/an/an/an/an/a


TBA

Assay Description
Active Moz protein was expressed as N-terminal fusion protein with a His6 tag in BL21 E. coli cells. Protein purification was performed via nickel-im...


Citation and Details
More data for this
Ligand-Target Pair
Histone acetyltransferase KAT6A


(Homo sapiens)
BDBM50518822
PNG
(CHEMBL4514005 | US10829446, Compound 27)
Show SMILES COc1ccccc1-c1cccc(c1)C(=O)NNS(=O)(=O)c1ccccc1
Show InChI InChI=1S/C20H18N2O4S/c1-26-19-13-6-5-12-18(19)15-8-7-9-16(14-15)20(23)21-22-27(24,25)17-10-3-2-4-11-17/h2-14,22H,1H3,(H,21,23)
PDB

UniProtKB/SwissProt

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PC cid
PC sid
UniChem
n/an/a 1.12E+4n/an/an/an/an/an/a


TBA

Assay Description
Active Moz protein was expressed as N-terminal fusion protein with a His6 tag in BL21 E. coli cells. Protein purification was performed via nickel-im...


Citation and Details
More data for this
Ligand-Target Pair
Histone acetyltransferase KAT6A


(Homo sapiens)
BDBM471856
PNG
(US10829446, Compound 98)
Show SMILES O=C(NNS(=O)(=O)c1ccc2ccccc2c1)c1cccc(c1)-c1cccnc1
Show InChI InChI=1S/C22H17N3O3S/c26-22(19-8-3-7-17(13-19)20-9-4-12-23-15-20)24-25-29(27,28)21-11-10-16-5-1-2-6-18(16)14-21/h1-15,25H,(H,24,26)
PDB

UniProtKB/SwissProt

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UniChem
n/an/a 1.31E+4n/an/an/an/an/an/a


TBA

Assay Description
Active Moz protein was expressed as N-terminal fusion protein with a His6 tag in BL21 E. coli cells. Protein purification was performed via nickel-im...


Citation and Details
More data for this
Ligand-Target Pair
Histone acetyltransferase KAT6A


(Homo sapiens)
BDBM50518820
PNG
(CHEMBL4465064 | US10829446, Compound 116)
Show SMILES O=C(NNS(=O)(=O)c1ccccc1)c1cccc(n1)-c1ccccc1
Show InChI InChI=1S/C18H15N3O3S/c22-18(20-21-25(23,24)15-10-5-2-6-11-15)17-13-7-12-16(19-17)14-8-3-1-4-9-14/h1-13,21H,(H,20,22)
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
n/an/a 1.66E+4n/an/an/an/an/an/a


TBA

Assay Description
Active Moz protein was expressed as N-terminal fusion protein with a His6 tag in BL21 E. coli cells. Protein purification was performed via nickel-im...


Citation and Details
More data for this
Ligand-Target Pair
Histone acetyltransferase KAT6A


(Homo sapiens)
BDBM50518876
PNG
(CHEMBL4516335 | US10829446, Compound 106)
Show SMILES O=C(NNS(=O)(=O)c1ccccc1)c1ccnc(c1)-c1ccccc1
Show InChI InChI=1S/C18H15N3O3S/c22-18(20-21-25(23,24)16-9-5-2-6-10-16)15-11-12-19-17(13-15)14-7-3-1-4-8-14/h1-13,21H,(H,20,22)
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
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UniChem
n/an/a 1.90E+4n/an/an/an/an/an/a


TBA

Assay Description
Active Moz protein was expressed as N-terminal fusion protein with a His6 tag in BL21 E. coli cells. Protein purification was performed via nickel-im...


Citation and Details
More data for this
Ligand-Target Pair
Histone acetyltransferase KAT6A


(Homo sapiens)
BDBM50518821
PNG
(CHEMBL4463217 | US10829446, Compound 109)
Show SMILES O=C(NNS(=O)(=O)c1ccccc1)c1cncc(c1)-c1ccccc1
Show InChI InChI=1S/C18H15N3O3S/c22-18(20-21-25(23,24)17-9-5-2-6-10-17)16-11-15(12-19-13-16)14-7-3-1-4-8-14/h1-13,21H,(H,20,22)
PDB

UniProtKB/SwissProt

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PC cid
PC sid
UniChem
n/an/a 2.13E+4n/an/an/an/an/an/a


TBA

Assay Description
Active Moz protein was expressed as N-terminal fusion protein with a His6 tag in BL21 E. coli cells. Protein purification was performed via nickel-im...


Citation and Details
More data for this
Ligand-Target Pair
Histone acetyltransferase KAT6A


(Homo sapiens)
BDBM50518859
PNG
(CHEMBL4453537 | US10829446, Compound 32)
Show SMILES Clc1ccc(cc1)-c1cccc(c1)C(=O)NNS(=O)(=O)c1ccccc1
Show InChI InChI=1S/C19H15ClN2O3S/c20-17-11-9-14(10-12-17)15-5-4-6-16(13-15)19(23)21-22-26(24,25)18-7-2-1-3-8-18/h1-13,22H,(H,21,23)
PDB

UniProtKB/SwissProt

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UniChem
n/an/a 2.58E+4n/an/an/an/an/an/a


TBA

Assay Description
Active Moz protein was expressed as N-terminal fusion protein with a His6 tag in BL21 E. coli cells. Protein purification was performed via nickel-im...


Citation and Details
More data for this
Ligand-Target Pair
Histone acetyltransferase KAT6A


(Homo sapiens)
BDBM50518796
PNG
(CHEMBL4542657 | US10829446, Compound 26)
Show SMILES COc1ccc(cc1)-c1cccc(c1)C(=O)NNS(=O)(=O)c1ccccc1
Show InChI InChI=1S/C20H18N2O4S/c1-26-18-12-10-15(11-13-18)16-6-5-7-17(14-16)20(23)21-22-27(24,25)19-8-3-2-4-9-19/h2-14,22H,1H3,(H,21,23)
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
n/an/a 4.00E+4n/an/an/an/an/an/a


TBA

Assay Description
Active Moz protein was expressed as N-terminal fusion protein with a His6 tag in BL21 E. coli cells. Protein purification was performed via nickel-im...


Citation and Details
More data for this
Ligand-Target Pair
Histone acetyltransferase KAT6A


(Homo sapiens)
BDBM50527326
PNG
(CHEMBL4443608 | US10829446, Compound 99)
Show SMILES Fc1ccccc1S(=O)(=O)NNC(=O)c1cccc(c1)-c1ccnnc1
Show InChI InChI=1S/C17H13FN4O3S/c18-15-6-1-2-7-16(15)26(24,25)22-21-17(23)13-5-3-4-12(10-13)14-8-9-19-20-11-14/h1-11,22H,(H,21,23)
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
n/an/a 6.37E+4n/an/an/an/an/an/a


TBA

Assay Description
Active Moz protein was expressed as N-terminal fusion protein with a His6 tag in BL21 E. coli cells. Protein purification was performed via nickel-im...


Citation and Details
More data for this
Ligand-Target Pair
Histone acetyltransferase KAT6A


(Homo sapiens)
BDBM471784
PNG
(US10829446, Compound 37)
Show SMILES Fc1c(Cl)cc(cc1C(=O)NNS(=O)(=O)c1ccccc1)-c1cccs1
Show InChI InChI=1S/C17H12ClFN2O3S2/c18-14-10-11(15-7-4-8-25-15)9-13(16(14)19)17(22)20-21-26(23,24)12-5-2-1-3-6-12/h1-10,21H,(H,20,22)
PDB

UniProtKB/SwissProt

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UniChem
n/an/a 8.54E+4n/an/an/an/an/an/a


TBA

Assay Description
Active Moz protein was expressed as N-terminal fusion protein with a His6 tag in BL21 E. coli cells. Protein purification was performed via nickel-im...


Citation and Details
More data for this
Ligand-Target Pair
Histone acetyltransferase KAT6A


(Homo sapiens)
BDBM471912
PNG
(US10829446, Compound 147)
Show SMILES Clc1cccc(c1)-c1cccc(CNNS(=O)(=O)c2ccccc2)c1
Show InChI InChI=1S/C19H17ClN2O2S/c20-18-9-5-8-17(13-18)16-7-4-6-15(12-16)14-21-22-25(23,24)19-10-2-1-3-11-19/h1-13,21-22H,14H2
PDB

UniProtKB/SwissProt

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UniChem
n/an/a 9.10E+4n/an/an/an/an/an/a


TBA

Assay Description
Active Moz protein was expressed as N-terminal fusion protein with a His6 tag in BL21 E. coli cells. Protein purification was performed via nickel-im...


Citation and Details
More data for this
Ligand-Target Pair
Histone acetyltransferase KAT6A


(Homo sapiens)
BDBM50527223
PNG
(CHEMBL4446366 | US10829446, Compound 108)
Show SMILES Fc1ccc(cc1C(=O)NNS(=O)(=O)c1ccccc1)-c1ccnnc1
Show InChI InChI=1S/C17H13FN4O3S/c18-16-7-6-12(13-8-9-19-20-11-13)10-15(16)17(23)21-22-26(24,25)14-4-2-1-3-5-14/h1-11,22H,(H,21,23)
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
n/an/a 1.25E+5n/an/an/an/an/an/a


TBA

Assay Description
Active Moz protein was expressed as N-terminal fusion protein with a His6 tag in BL21 E. coli cells. Protein purification was performed via nickel-im...


Citation and Details
More data for this
Ligand-Target Pair
Histone acetyltransferase KAT6A


(Homo sapiens)
BDBM50518826
PNG
(CHEMBL4473737 | US10829446, Compound 12)
Show SMILES O=C(NNS(=O)(=O)c1ccccc1)c1cccc(c1)-c1cncnc1
Show InChI InChI=1S/C17H14N4O3S/c22-17(20-21-25(23,24)16-7-2-1-3-8-16)14-6-4-5-13(9-14)15-10-18-12-19-11-15/h1-12,21H,(H,20,22)
PDB

UniProtKB/SwissProt

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PC cid
PC sid
UniChem
n/an/a 1.25E+5n/an/an/an/an/an/a


TBA

Assay Description
Active Moz protein was expressed as N-terminal fusion protein with a His6 tag in BL21 E. coli cells. Protein purification was performed via nickel-im...


Citation and Details
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%