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Patent code US10829496

Compile Data Set for Download or QSAR
Found 29 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Interleukin-1 receptor-associated kinase 4


(Homo sapiens (Human))
BDBM472800
PNG
(3-(((2S,3 S,4S)-3-ethyl-4-fluoro-5-oxopyrrolidin-2...)
Show SMILES CC[C@H]1[C@@H](COc2csc3cc(C(N)=O)c(OC)cc23)NC(=O)[C@H]1F
Show InChI InChI=1S/C17H19FN2O4S/c1-3-8-11(20-17(22)15(8)18)6-24-13-7-25-14-5-10(16(19)21)12(23-2)4-9(13)14/h4-5,7-8,11,15H,3,6H2,1-2H3,(H2,19,21)(H,20,22)/t8-,11+,15-/m0/s1
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n/an/a 0.400n/an/an/an/an/an/a


TBA

Assay Description
The assays were performed in U-bottom 384-well plates. The final assay volume was 30 μL prepared from 15 μL additions of enzyme and substra...


Citation and Details
More data for this
Ligand-Target Pair
Interleukin-1 receptor-associated kinase 4


(Homo sapiens (Human))
BDBM472797
PNG
(3-(((2S,3S)-3-Ethyl-4,4-difluoro-5-oxopyrrolidin-2...)
Show SMILES CC[C@H]1[C@@H](COc2csc3cc(C(N)=O)c(OC)nc23)NC(=O)C1(F)F
Show InChI InChI=1S/C16H17F2N3O4S/c1-3-8-9(20-15(23)16(8,17)18)5-25-10-6-26-11-4-7(13(19)22)14(24-2)21-12(10)11/h4,6,8-9H,3,5H2,1-2H3,(H2,19,22)(H,20,23)/t8-,9+/m0/s1
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n/an/a 0.600n/an/an/an/an/an/a


TBA

Assay Description
The assays were performed in U-bottom 384-well plates. The final assay volume was 30 μL prepared from 15 μL additions of enzyme and substra...


Citation and Details
More data for this
Ligand-Target Pair
Interleukin-1 receptor-associated kinase 4


(Homo sapiens (Human))
BDBM472804
PNG
(US10829496, Example 8)
Show SMILES CC[C@H]1[C@@H](COc2csc3cc(C(N)=O)c(OC)nc23)NC(=O)[C@@H]1F
Show InChI InChI=1S/C16H18FN3O4S/c1-3-7-9(19-15(22)12(7)17)5-24-10-6-25-11-4-8(14(18)21)16(23-2)20-13(10)11/h4,6-7,9,12H,3,5H2,1-2H3,(H2,18,21)(H,19,22)/t7-,9+,12+/m0/s1
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n/an/a 0.700n/an/an/an/an/an/a


TBA

Assay Description
The assays were performed in U-bottom 384-well plates. The final assay volume was 30 μL prepared from 15 μL additions of enzyme and substra...


Citation and Details
More data for this
Ligand-Target Pair
Interleukin-1 receptor-associated kinase 4


(Homo sapiens (Human))
BDBM472825
PNG
(US10829496, Example 29)
Show SMILES CC[C@@H]1CC(=O)N[C@@H]1COc1csc2cc(C(N)=O)c(OC)cc12
Show InChI InChI=1S/C17H20N2O4S/c1-3-9-4-16(20)19-12(9)7-23-14-8-24-15-6-11(17(18)21)13(22-2)5-10(14)15/h5-6,8-9,12H,3-4,7H2,1-2H3,(H2,18,21)(H,19,20)/t9-,12-/m1/s1
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n/an/a 0.900n/an/an/an/an/an/a


TBA

Assay Description
The assays were performed in U-bottom 384-well plates. The final assay volume was 30 μL prepared from 15 μL additions of enzyme and substra...


Citation and Details
More data for this
Ligand-Target Pair
Interleukin-1 receptor-associated kinase 4


(Homo sapiens (Human))
BDBM472802
PNG
(US10829496, Example 6)
Show SMILES CC[C@@H]1CC(=O)N[C@@H]1COc1csc2cc(C(N)=O)c(OC)nc12
Show InChI InChI=1S/C16H19N3O4S/c1-3-8-4-13(20)18-10(8)6-23-11-7-24-12-5-9(15(17)21)16(22-2)19-14(11)12/h5,7-8,10H,3-4,6H2,1-2H3,(H2,17,21)(H,18,20)/t8-,10-/m1/s1
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n/an/a 1n/an/an/an/an/an/a


TBA

Assay Description
The assays were performed in U-bottom 384-well plates. The final assay volume was 30 μL prepared from 15 μL additions of enzyme and substra...


Citation and Details
More data for this
Ligand-Target Pair
Interleukin-1 receptor-associated kinase 4


(Homo sapiens (Human))
BDBM472823
PNG
(US10829496, Example 27)
Show SMILES COc1nc2c(OC[C@H]3NC(=O)[C@H](F)[C@H]3C)csc2cc1C(N)=O
Show InChI InChI=1S/C15H16FN3O4S/c1-6-8(18-14(21)11(6)16)4-23-9-5-24-10-3-7(13(17)20)15(22-2)19-12(9)10/h3,5-6,8,11H,4H2,1-2H3,(H2,17,20)(H,18,21)/t6-,8+,11+/m0/s1
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n/an/a 1.10n/an/an/an/an/an/a


TBA

Assay Description
The assays were performed in U-bottom 384-well plates. The final assay volume was 30 μL prepared from 15 μL additions of enzyme and substra...


Citation and Details
More data for this
Ligand-Target Pair
Interleukin-1 receptor-associated kinase 4


(Homo sapiens (Human))
BDBM472798
PNG
(3-(((2S,3S,4S)-3-Ethyl-4-fluoro-5-oxopyrrolidin-2-...)
Show SMILES CC[C@H]1[C@@H](COc2csc3cc(C(N)=O)c(OC)nc23)NC(=O)[C@H]1F
Show InChI InChI=1S/C16H18FN3O4S/c1-3-7-9(19-15(22)12(7)17)5-24-10-6-25-11-4-8(14(18)21)16(23-2)20-13(10)11/h4,6-7,9,12H,3,5H2,1-2H3,(H2,18,21)(H,19,22)/t7-,9+,12-/m0/s1
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n/an/a 1.20n/an/an/an/an/an/a


TBA

Assay Description
The assays were performed in U-bottom 384-well plates. The final assay volume was 30 μL prepared from 15 μL additions of enzyme and substra...


Citation and Details
More data for this
Ligand-Target Pair
Interleukin-1 receptor-associated kinase 4


(Homo sapiens (Human))
BDBM472817
PNG
(US10829496, Example 21)
Show SMILES COc1nc2c(OC[C@H]3NC(=O)C(F)(F)[C@H]3C)csc2cc1C(N)=O
Show InChI InChI=1S/C15H15F2N3O4S/c1-6-8(19-14(22)15(6,16)17)4-24-9-5-25-10-3-7(12(18)21)13(23-2)20-11(9)10/h3,5-6,8H,4H2,1-2H3,(H2,18,21)(H,19,22)/t6-,8+/m0/s1
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n/an/a 1.30n/an/an/an/an/an/a


TBA

Assay Description
The assays were performed in U-bottom 384-well plates. The final assay volume was 30 μL prepared from 15 μL additions of enzyme and substra...


Citation and Details
More data for this
Ligand-Target Pair
Interleukin-1 receptor-associated kinase 4


(Homo sapiens (Human))
BDBM472819
PNG
(US10829496, Example 23)
Show SMILES CC[C@H]1[C@@H](COc2csc3cc(C(N)=O)c(OC(C)C)nc23)NC(=O)[C@H]1F
Show InChI InChI=1S/C18H22FN3O4S/c1-4-9-11(21-17(24)14(9)19)6-25-12-7-27-13-5-10(16(20)23)18(22-15(12)13)26-8(2)3/h5,7-9,11,14H,4,6H2,1-3H3,(H2,20,23)(H,21,24)/t9-,11+,14-/m0/s1
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n/an/a 1.40n/an/an/an/an/an/a


TBA

Assay Description
The assays were performed in U-bottom 384-well plates. The final assay volume was 30 μL prepared from 15 μL additions of enzyme and substra...


Citation and Details
More data for this
Ligand-Target Pair
Interleukin-1 receptor-associated kinase 4


(Homo sapiens (Human))
BDBM472808
PNG
(US10829496, Example 12)
Show SMILES COc1nc2c(OC[C@H]3NC(=O)C[C@H]3C(F)F)csc2cc1C(N)=O
Show InChI InChI=1S/C15H15F2N3O4S/c1-23-15-7(14(18)22)2-10-12(20-15)9(5-25-10)24-4-8-6(13(16)17)3-11(21)19-8/h2,5-6,8,13H,3-4H2,1H3,(H2,18,22)(H,19,21)/t6-,8-/m1/s1
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n/an/a 2.5n/an/an/an/an/an/a


TBA

Assay Description
The assays were performed in U-bottom 384-well plates. The final assay volume was 30 μL prepared from 15 μL additions of enzyme and substra...


Citation and Details
More data for this
Ligand-Target Pair
Interleukin-1 receptor-associated kinase 4


(Homo sapiens (Human))
BDBM472814
PNG
(US10829496, Example 18)
Show SMILES COc1nc2c(OC[C@H]3NC(=O)[C@H](F)[C@H]3C3CC3)csc2cc1C(N)=O
Show InChI InChI=1S/C17H18FN3O4S/c1-24-17-8(15(19)22)4-11-14(21-17)10(6-26-11)25-5-9-12(7-2-3-7)13(18)16(23)20-9/h4,6-7,9,12-13H,2-3,5H2,1H3,(H2,19,22)(H,20,23)/t9-,12+,13-/m1/s1
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n/an/a 2.80n/an/an/an/an/an/a


TBA

Assay Description
The assays were performed in U-bottom 384-well plates. The final assay volume was 30 μL prepared from 15 μL additions of enzyme and substra...


Citation and Details
More data for this
Ligand-Target Pair
Interleukin-1 receptor-associated kinase 4


(Homo sapiens (Human))
BDBM472807
PNG
(US10829496, Example 11)
Show SMILES COc1nc2c(OC[C@@H]3C[C@@H](F)C(=O)N3)csc2cc1C(N)=O
Show InChI InChI=1S/C14H14FN3O4S/c1-21-14-7(12(16)19)3-10-11(18-14)9(5-23-10)22-4-6-2-8(15)13(20)17-6/h3,5-6,8H,2,4H2,1H3,(H2,16,19)(H,17,20)/t6-,8+/m0/s1
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n/an/a 4n/an/an/an/an/an/a


TBA

Assay Description
The assays were performed in U-bottom 384-well plates. The final assay volume was 30 μL prepared from 15 μL additions of enzyme and substra...


Citation and Details
More data for this
Ligand-Target Pair
Interleukin-1 receptor-associated kinase 4


(Homo sapiens (Human))
BDBM472813
PNG
(US10829496, Example 17)
Show SMILES COc1nc2c(OC[C@H]3NC(=O)C[C@H]3C)csc2cc1C(N)=O
Show InChI InChI=1S/C15H17N3O4S/c1-7-3-12(19)17-9(7)5-22-10-6-23-11-4-8(14(16)20)15(21-2)18-13(10)11/h4,6-7,9H,3,5H2,1-2H3,(H2,16,20)(H,17,19)/t7-,9-/m1/s1
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n/an/a 6n/an/an/an/an/an/a


TBA

Assay Description
The assays were performed in U-bottom 384-well plates. The final assay volume was 30 μL prepared from 15 μL additions of enzyme and substra...


Citation and Details
More data for this
Ligand-Target Pair
Interleukin-1 receptor-associated kinase 4


(Homo sapiens (Human))
BDBM472822
PNG
(US10829496, Example 26)
Show SMILES CC[C@@H]1OC(=O)N[C@@H]1COc1csc2cc(C(N)=O)c(OC)nc12
Show InChI InChI=1S/C15H17N3O5S/c1-3-9-8(17-15(20)23-9)5-22-10-6-24-11-4-7(13(16)19)14(21-2)18-12(10)11/h4,6,8-9H,3,5H2,1-2H3,(H2,16,19)(H,17,20)/t8-,9+/m1/s1
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n/an/a 6.80n/an/an/an/an/an/a


TBA

Assay Description
The assays were performed in U-bottom 384-well plates. The final assay volume was 30 μL prepared from 15 μL additions of enzyme and substra...


Citation and Details
More data for this
Ligand-Target Pair
Interleukin-1 receptor-associated kinase 4


(Homo sapiens (Human))
BDBM472815
PNG
(US10829496, Example 19)
Show SMILES CC[C@@H]1CC(=O)N[C@@H]1COc1c(C)sc2cc(C(N)=O)c(OC)nc12
Show InChI InChI=1S/C17H21N3O4S/c1-4-9-5-13(21)19-11(9)7-24-15-8(2)25-12-6-10(16(18)22)17(23-3)20-14(12)15/h6,9,11H,4-5,7H2,1-3H3,(H2,18,22)(H,19,21)/t9-,11-/m1/s1
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n/an/a 10.6n/an/an/an/an/an/a


TBA

Assay Description
The assays were performed in U-bottom 384-well plates. The final assay volume was 30 μL prepared from 15 μL additions of enzyme and substra...


Citation and Details
More data for this
Ligand-Target Pair
Interleukin-1 receptor-associated kinase 4


(Homo sapiens (Human))
BDBM472824
PNG
(US10829496, Example 28)
Show SMILES COc1nc2c(OC[C@H]3NC(=O)[C@@H](F)[C@H]3C)csc2cc1C(N)=O
Show InChI InChI=1S/C15H16FN3O4S/c1-6-8(18-14(21)11(6)16)4-23-9-5-24-10-3-7(13(17)20)15(22-2)19-12(9)10/h3,5-6,8,11H,4H2,1-2H3,(H2,17,20)(H,18,21)/t6-,8+,11-/m0/s1
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n/an/a 13.3n/an/an/an/an/an/a


TBA

Assay Description
The assays were performed in U-bottom 384-well plates. The final assay volume was 30 μL prepared from 15 μL additions of enzyme and substra...


Citation and Details
More data for this
Ligand-Target Pair
Interleukin-1 receptor-associated kinase 4


(Homo sapiens (Human))
BDBM472816
PNG
(US10829496, Example 20)
Show SMILES CC[C@@H]1CC(=O)N[C@@H]1COc1csc2cc(C(N)=O)c(OC3CC3)nc12
Show InChI InChI=1S/C18H21N3O4S/c1-2-9-5-15(22)20-12(9)7-24-13-8-26-14-6-11(17(19)23)18(21-16(13)14)25-10-3-4-10/h6,8-10,12H,2-5,7H2,1H3,(H2,19,23)(H,20,22)/t9-,12-/m1/s1
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n/an/a 19.1n/an/an/an/an/an/a


TBA

Assay Description
The assays were performed in U-bottom 384-well plates. The final assay volume was 30 μL prepared from 15 μL additions of enzyme and substra...


Citation and Details
More data for this
Ligand-Target Pair
Interleukin-1 receptor-associated kinase 4


(Homo sapiens (Human))
BDBM472820
PNG
(US10829496, Example 24)
Show SMILES CC[C@H]1[C@@H](COc2csc3cc(C(N)=O)c(OC4CC4)nc23)NC(=O)[C@H]1F
Show InChI InChI=1S/C18H20FN3O4S/c1-2-9-11(21-17(24)14(9)19)6-25-12-7-27-13-5-10(16(20)23)18(22-15(12)13)26-8-3-4-8/h5,7-9,11,14H,2-4,6H2,1H3,(H2,20,23)(H,21,24)/t9-,11+,14-/m0/s1
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n/an/a 20.2n/an/an/an/an/an/a


TBA

Assay Description
The assays were performed in U-bottom 384-well plates. The final assay volume was 30 μL prepared from 15 μL additions of enzyme and substra...


Citation and Details
More data for this
Ligand-Target Pair
Interleukin-1 receptor-associated kinase 4


(Homo sapiens (Human))
BDBM472801
PNG
(US10829496, Example 5)
Show SMILES COc1nc2c(OC[C@@H]3CCC(=O)N3)csc2cc1C(N)=O
Show InChI InChI=1S/C14H15N3O4S/c1-20-14-8(13(15)19)4-10-12(17-14)9(6-22-10)21-5-7-2-3-11(18)16-7/h4,6-7H,2-3,5H2,1H3,(H2,15,19)(H,16,18)/t7-/m0/s1
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n/an/a 20.3n/an/an/an/an/an/a


TBA

Assay Description
The assays were performed in U-bottom 384-well plates. The final assay volume was 30 μL prepared from 15 μL additions of enzyme and substra...


Citation and Details
More data for this
Ligand-Target Pair
Interleukin-1 receptor-associated kinase 4


(Homo sapiens (Human))
BDBM472818
PNG
(US10829496, Example 22)
Show SMILES CC[C@H]1[C@@H](COc2c(C)sc3cc(C(N)=O)c(OC)nc23)NC(=O)[C@H]1F
Show InChI InChI=1S/C17H20FN3O4S/c1-4-8-10(20-16(23)12(8)18)6-25-14-7(2)26-11-5-9(15(19)22)17(24-3)21-13(11)14/h5,8,10,12H,4,6H2,1-3H3,(H2,19,22)(H,20,23)/t8-,10+,12-/m0/s1
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n/an/a 33.6n/an/an/an/an/an/a


TBA

Assay Description
The assays were performed in U-bottom 384-well plates. The final assay volume was 30 μL prepared from 15 μL additions of enzyme and substra...


Citation and Details
More data for this
Ligand-Target Pair
Interleukin-1 receptor-associated kinase 4


(Homo sapiens (Human))
BDBM472809
PNG
(US10829496, Example 13 | US10829496, Example 14)
Show SMILES COc1nc2c(OC[C@@H]3CC(C)C(=O)N3)csc2cc1C(N)=O
Show InChI InChI=1S/C15H17N3O4S/c1-7-3-8(17-14(7)20)5-22-10-6-23-11-4-9(13(16)19)15(21-2)18-12(10)11/h4,6-8H,3,5H2,1-2H3,(H2,16,19)(H,17,20)/t7?,8-/m0/s1
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n/an/a 36.2n/an/an/an/an/an/a


TBA

Assay Description
The assays were performed in U-bottom 384-well plates. The final assay volume was 30 μL prepared from 15 μL additions of enzyme and substra...


Citation and Details
More data for this
Ligand-Target Pair
Interleukin-1 receptor-associated kinase 4


(Homo sapiens (Human))
BDBM472811
PNG
(US10829496, Example 15 | US10829496, Example 16)
Show SMILES CCC1C[C@@H](COc2csc3cc(C(N)=O)c(OC)nc23)NC1=O
Show InChI InChI=1S/C16H19N3O4S/c1-3-8-4-9(18-15(8)21)6-23-11-7-24-12-5-10(14(17)20)16(22-2)19-13(11)12/h5,7-9H,3-4,6H2,1-2H3,(H2,17,20)(H,18,21)/t8?,9-/m0/s1
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n/an/a 63.4n/an/an/an/an/an/a


TBA

Assay Description
The assays were performed in U-bottom 384-well plates. The final assay volume was 30 μL prepared from 15 μL additions of enzyme and substra...


Citation and Details
More data for this
Ligand-Target Pair
Interleukin-1 receptor-associated kinase 4


(Homo sapiens (Human))
BDBM472811
PNG
(US10829496, Example 15 | US10829496, Example 16)
Show SMILES CCC1C[C@@H](COc2csc3cc(C(N)=O)c(OC)nc23)NC1=O
Show InChI InChI=1S/C16H19N3O4S/c1-3-8-4-9(18-15(8)21)6-23-11-7-24-12-5-10(14(17)20)16(22-2)19-13(11)12/h5,7-9H,3-4,6H2,1-2H3,(H2,17,20)(H,18,21)/t8?,9-/m0/s1
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n/an/a 98.1n/an/an/an/an/an/a


TBA

Assay Description
The assays were performed in U-bottom 384-well plates. The final assay volume was 30 μL prepared from 15 μL additions of enzyme and substra...


Citation and Details
More data for this
Ligand-Target Pair
Interleukin-1 receptor-associated kinase 4


(Homo sapiens (Human))
BDBM472821
PNG
(US10829496, Example 25)
Show SMILES COc1nc2c(OC[C@@H]3CCC(=O)N3)c(C)sc2cc1C(N)=O
Show InChI InChI=1S/C15H17N3O4S/c1-7-13(22-6-8-3-4-11(19)17-8)12-10(23-7)5-9(14(16)20)15(18-12)21-2/h5,8H,3-4,6H2,1-2H3,(H2,16,20)(H,17,19)/t8-/m0/s1
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n/an/a 128n/an/an/an/an/an/a


TBA

Assay Description
The assays were performed in U-bottom 384-well plates. The final assay volume was 30 μL prepared from 15 μL additions of enzyme and substra...


Citation and Details
More data for this
Ligand-Target Pair
Interleukin-1 receptor-associated kinase 4


(Homo sapiens (Human))
BDBM472805
PNG
(US10829496, Example 9)
Show SMILES CC[C@H]1[C@@H](COc2csc3cc(C(N)=O)c(OC)nc23)NC(=O)C11CC1
Show InChI InChI=1S/C18H21N3O4S/c1-3-10-11(20-17(23)18(10)4-5-18)7-25-12-8-26-13-6-9(15(19)22)16(24-2)21-14(12)13/h6,8,10-11H,3-5,7H2,1-2H3,(H2,19,22)(H,20,23)/t10-,11+/m0/s1
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n/an/a 130n/an/an/an/an/an/a


TBA

Assay Description
The assays were performed in U-bottom 384-well plates. The final assay volume was 30 μL prepared from 15 μL additions of enzyme and substra...


Citation and Details
More data for this
Ligand-Target Pair
Interleukin-1 receptor-associated kinase 4


(Homo sapiens (Human))
BDBM472809
PNG
(US10829496, Example 13 | US10829496, Example 14)
Show SMILES COc1nc2c(OC[C@@H]3CC(C)C(=O)N3)csc2cc1C(N)=O
Show InChI InChI=1S/C15H17N3O4S/c1-7-3-8(17-14(7)20)5-22-10-6-23-11-4-9(13(16)19)15(21-2)18-12(10)11/h4,6-8H,3,5H2,1-2H3,(H2,16,19)(H,17,20)/t7?,8-/m0/s1
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n/an/a 459n/an/an/an/an/an/a


TBA

Assay Description
The assays were performed in U-bottom 384-well plates. The final assay volume was 30 μL prepared from 15 μL additions of enzyme and substra...


Citation and Details
More data for this
Ligand-Target Pair
Interleukin-1 receptor-associated kinase 4


(Homo sapiens (Human))
BDBM472799
PNG
((S)-5-Methoxy-3-((5-oxopyrrolidin-2-yl)methoxy)thi...)
Show SMILES COc1cc2c(OC[C@@H]3CCC(=O)N3)csc2nc1C(N)=O
Show InChI InChI=1S/C14H15N3O4S/c1-20-9-4-8-10(21-5-7-2-3-11(18)16-7)6-22-14(8)17-12(9)13(15)19/h4,6-7H,2-3,5H2,1H3,(H2,15,19)(H,16,18)/t7-/m0/s1
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n/an/a 558n/an/an/an/an/an/a


TBA

Assay Description
The assays were performed in U-bottom 384-well plates. The final assay volume was 30 μL prepared from 15 μL additions of enzyme and substra...


Citation and Details
More data for this
Ligand-Target Pair
Interleukin-1 receptor-associated kinase 4


(Homo sapiens (Human))
BDBM472806
PNG
(US10829496, Example 10)
Show SMILES CC[C@H]1[C@@H](COc2csc3cc(C(N)=O)c(OC)nc23)NC(=O)C1(C)C
Show InChI InChI=1S/C18H23N3O4S/c1-5-10-11(20-17(23)18(10,2)3)7-25-12-8-26-13-6-9(15(19)22)16(24-4)21-14(12)13/h6,8,10-11H,5,7H2,1-4H3,(H2,19,22)(H,20,23)/t10-,11+/m0/s1
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n/an/a 595n/an/an/an/an/an/a


TBA

Assay Description
The assays were performed in U-bottom 384-well plates. The final assay volume was 30 μL prepared from 15 μL additions of enzyme and substra...


Citation and Details
More data for this
Ligand-Target Pair
Interleukin-1 receptor-associated kinase 4


(Homo sapiens (Human))
BDBM472803
PNG
(US10829496, Example 7)
Show SMILES COc1nc2c(OCC3COCC(=O)N3)csc2cc1C(N)=O
Show InChI InChI=1S/C14H15N3O5S/c1-20-14-8(13(15)19)2-10-12(17-14)9(6-23-10)22-4-7-3-21-5-11(18)16-7/h2,6-7H,3-5H2,1H3,(H2,15,19)(H,16,18)
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n/an/a 615n/an/an/an/an/an/a


TBA

Assay Description
The assays were performed in U-bottom 384-well plates. The final assay volume was 30 μL prepared from 15 μL additions of enzyme and substra...


Citation and Details
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%