Compile Data Set for Download or QSAR
maximum 50k data
Found 5 Enz. Inhib. hit(s) with all data for entry = 9523
TargetBeta-secretase 1(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM472830(US10829500, Exam. 5)
Affinity DataIC50:  28nMAssay Description:It has been found that the compounds of the present invention are associated with inhibition of BACE1 activity. More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBeta-secretase 1(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM472828(US10829500, Exam. 3)
Affinity DataIC50:  36nMAssay Description:It has been found that the compounds of the present invention are associated with inhibition of BACE1 activity. More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBeta-secretase 1(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM472827(US10829500, Exam. 2)
Affinity DataIC50:  49nMAssay Description:It has been found that the compounds of the present invention are associated with inhibition of BACE1 activity. More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBeta-secretase 1(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM472826(US10829500, Exam. 1)
Affinity DataIC50:  86nMAssay Description:It has been found that the compounds of the present invention are associated with inhibition of BACE1 activity. More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBeta-secretase 1(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM472829(US10829500, Exam. 4)
Affinity DataIC50:  96nMAssay Description:It has been found that the compounds of the present invention are associated with inhibition of BACE1 activity. More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent