Compile Data Set for Download or QSAR
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Found 22 Enz. Inhib. hit(s) with all data for entry = 9527
TargetMu-type opioid receptor(Homo sapiens (Human))
Mebias Discovery

US Patent
LigandPNGBDBM86253(CAS_100929-53-1 | DAMGO | NSC_104742 | US10836728,...)
Affinity DataEC50: <10nMAssay Description:G-protein signaling was measured via second messenger cAMP modulation. Detection of cAMP modulation was accomplished in the PathHunter human OPRM1 (&...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetBeta-arrestin-1(Homo sapiens (Human))
Mebias Discovery

US Patent
LigandPNGBDBM472836(3-[3-Dimethylaminomethyl-4-hydroxy-1-(3-phenyl-pro...)
Affinity DataEC50:  270nMAssay Description:The DISCOVERX PATHHUNTER® β-Arrestin assay is used to measure β-arrestin-2 activity. The technology is based on Enzyme Fragment Complementa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMu-type opioid receptor(Homo sapiens (Human))
Mebias Discovery

US Patent
LigandPNGBDBM224017((+)-Morphine | US10752592, Compound morphine | US1...)
Affinity DataEC50:  60nMAssay Description:G-protein signaling was measured via second messenger cAMP modulation. Detection of cAMP modulation was accomplished in the PathHunter human OPRM1 (&...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBeta-arrestin-1(Homo sapiens (Human))
Mebias Discovery

US Patent
LigandPNGBDBM224017((+)-Morphine | US10752592, Compound morphine | US1...)
Affinity DataEC50:  310nMAssay Description:The DISCOVERX PATHHUNTER® β-Arrestin assay is used to measure β-arrestin-2 activity. The technology is based on Enzyme Fragment Complementa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMu-type opioid receptor(Homo sapiens (Human))
Mebias Discovery

US Patent
LigandPNGBDBM472704(3-(1-(2-Chloro-4-fluorobenzyl)-3-((dimethylamino)m...)
Affinity DataEC50:  102nMAssay Description:G-protein signaling was measured via second messenger cAMP modulation. Detection of cAMP modulation was accomplished in the PathHunter human OPRM1 (&...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBeta-arrestin-1(Homo sapiens (Human))
Mebias Discovery

US Patent
LigandPNGBDBM472704(3-(1-(2-Chloro-4-fluorobenzyl)-3-((dimethylamino)m...)
Affinity DataEC50:  2.56E+3nMAssay Description:The DISCOVERX PATHHUNTER® β-Arrestin assay is used to measure β-arrestin-2 activity. The technology is based on Enzyme Fragment Complementa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMu-type opioid receptor(Homo sapiens (Human))
Mebias Discovery

US Patent
LigandPNGBDBM472714(US10836728, Compound Ent-A-syn-(6))
Affinity DataEC50:  163nMAssay Description:G-protein signaling was measured via second messenger cAMP modulation. Detection of cAMP modulation was accomplished in the PathHunter human OPRM1 (&...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBeta-arrestin-1(Homo sapiens (Human))
Mebias Discovery

US Patent
LigandPNGBDBM472714(US10836728, Compound Ent-A-syn-(6))
Affinity DataEC50:  3.17E+3nMAssay Description:The DISCOVERX PATHHUNTER® β-Arrestin assay is used to measure β-arrestin-2 activity. The technology is based on Enzyme Fragment Complementa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMu-type opioid receptor(Homo sapiens (Human))
Mebias Discovery

US Patent
LigandPNGBDBM472715(US10836728, Compound Ent-B-syn-(6))
Affinity DataEC50:  463nMAssay Description:G-protein signaling was measured via second messenger cAMP modulation. Detection of cAMP modulation was accomplished in the PathHunter human OPRM1 (&...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBeta-arrestin-1(Homo sapiens (Human))
Mebias Discovery

US Patent
LigandPNGBDBM472715(US10836728, Compound Ent-B-syn-(6))
Affinity DataEC50:  3.67E+3nMAssay Description:The DISCOVERX PATHHUNTER® β-Arrestin assay is used to measure β-arrestin-2 activity. The technology is based on Enzyme Fragment Complementa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMu-type opioid receptor(Homo sapiens (Human))
Mebias Discovery

US Patent
LigandPNGBDBM472721(3-(3-((Dimethylamino)methyl)-4-hydroxy-1-phenethyl...)
Affinity DataEC50:  34nMAssay Description:G-protein signaling was measured via second messenger cAMP modulation. Detection of cAMP modulation was accomplished in the PathHunter human OPRM1 (&...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBeta-arrestin-1(Homo sapiens (Human))
Mebias Discovery

US Patent
LigandPNGBDBM472721(3-(3-((Dimethylamino)methyl)-4-hydroxy-1-phenethyl...)
Affinity DataEC50:  830nMAssay Description:The DISCOVERX PATHHUNTER® β-Arrestin assay is used to measure β-arrestin-2 activity. The technology is based on Enzyme Fragment Complementa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMu-type opioid receptor(Homo sapiens (Human))
Mebias Discovery

US Patent
LigandPNGBDBM472831(US10836728, Compound (11))
Affinity DataEC50:  550nMAssay Description:G-protein signaling was measured via second messenger cAMP modulation. Detection of cAMP modulation was accomplished in the PathHunter human OPRM1 (&...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBeta-arrestin-1(Homo sapiens (Human))
Mebias Discovery

US Patent
LigandPNGBDBM472831(US10836728, Compound (11))
Affinity DataEC50:  1.07E+4nMAssay Description:The DISCOVERX PATHHUNTER® β-Arrestin assay is used to measure β-arrestin-2 activity. The technology is based on Enzyme Fragment Complementa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMu-type opioid receptor(Homo sapiens (Human))
Mebias Discovery

US Patent
LigandPNGBDBM472832(US10836728, Compound (15))
Affinity DataEC50:  67nMAssay Description:G-protein signaling was measured via second messenger cAMP modulation. Detection of cAMP modulation was accomplished in the PathHunter human OPRM1 (&...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBeta-arrestin-1(Homo sapiens (Human))
Mebias Discovery

US Patent
LigandPNGBDBM472832(US10836728, Compound (15))
Affinity DataEC50: >1.00E+5nMAssay Description:The DISCOVERX PATHHUNTER® β-Arrestin assay is used to measure β-arrestin-2 activity. The technology is based on Enzyme Fragment Complementa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMu-type opioid receptor(Homo sapiens (Human))
Mebias Discovery

US Patent
LigandPNGBDBM472834(US10836728, Compound (17))
Affinity DataEC50:  467nMAssay Description:G-protein signaling was measured via second messenger cAMP modulation. Detection of cAMP modulation was accomplished in the PathHunter human OPRM1 (&...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBeta-arrestin-1(Homo sapiens (Human))
Mebias Discovery

US Patent
LigandPNGBDBM472834(US10836728, Compound (17))
Affinity DataEC50: >1.00E+5nMAssay Description:The DISCOVERX PATHHUNTER® β-Arrestin assay is used to measure β-arrestin-2 activity. The technology is based on Enzyme Fragment Complementa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMu-type opioid receptor(Homo sapiens (Human))
Mebias Discovery

US Patent
LigandPNGBDBM472835(3-(3-((Dimethylamino)methyl)-4-hydroxy-1-(4-hydrox...)
Affinity DataEC50:  160nMAssay Description:G-protein signaling was measured via second messenger cAMP modulation. Detection of cAMP modulation was accomplished in the PathHunter human OPRM1 (&...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBeta-arrestin-1(Homo sapiens (Human))
Mebias Discovery

US Patent
LigandPNGBDBM472835(3-(3-((Dimethylamino)methyl)-4-hydroxy-1-(4-hydrox...)
Affinity DataEC50:  3.10E+3nMAssay Description:The DISCOVERX PATHHUNTER® β-Arrestin assay is used to measure β-arrestin-2 activity. The technology is based on Enzyme Fragment Complementa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMu-type opioid receptor(Homo sapiens (Human))
Mebias Discovery

US Patent
LigandPNGBDBM472836(3-[3-Dimethylaminomethyl-4-hydroxy-1-(3-phenyl-pro...)
Affinity DataEC50:  10nMAssay Description:G-protein signaling was measured via second messenger cAMP modulation. Detection of cAMP modulation was accomplished in the PathHunter human OPRM1 (&...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBeta-arrestin-1(Homo sapiens (Human))
Mebias Discovery

US Patent
LigandPNGBDBM86253(CAS_100929-53-1 | DAMGO | NSC_104742 | US10836728,...)
Affinity DataEC50:  60nMAssay Description:The DISCOVERX PATHHUNTER® β-Arrestin assay is used to measure β-arrestin-2 activity. The technology is based on Enzyme Fragment Complementa...More data for this Ligand-Target Pair
In DepthDetails US Patent