Compile Data Set for Download or QSAR
maximum 50k data
Found 100 Enz. Inhib. hit(s) with all data for entry = 9538
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Kronos Bio

US Patent
LigandPNGBDBM473090(6-(1H-indazol-6-yl)-N- {4H,6H,7H- pyrazolo[3,2- c]...)
Affinity DataIC50:  2.00E+3nMAssay Description:A master mix minus Syk enzyme is prepared containing 1X Cell Signaling kinase buffer (25 mM Tris-HCl, pH 7.5, 5 mM beta-glycerophosphate, 2 mM dithio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Kronos Bio

US Patent
LigandPNGBDBM473114(2-hydroxy-1-(4-{6-[(6- {1H-pyrrolo[3,2- b]pyridin-...)
Affinity DataIC50:  2.60E+3nMAssay Description:A master mix minus Syk enzyme is prepared containing 1X Cell Signaling kinase buffer (25 mM Tris-HCl, pH 7.5, 5 mM beta-glycerophosphate, 2 mM dithio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Kronos Bio

US Patent
LigandPNGBDBM473125(1-(2-(6-(1H-pyrrolo[3,2- b]pyridin-6- yl)imidazo[1...)
Affinity DataIC50:  2.80E+3nMAssay Description:A master mix minus Syk enzyme is prepared containing 1X Cell Signaling kinase buffer (25 mM Tris-HCl, pH 7.5, 5 mM beta-glycerophosphate, 2 mM dithio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Kronos Bio

US Patent
LigandPNGBDBM473118(N-{5-methanesulfonyl- 4H,5H,6H,7H- pyrazolo[1,5-a]...)
Affinity DataIC50:  3.70E+3nMAssay Description:A master mix minus Syk enzyme is prepared containing 1X Cell Signaling kinase buffer (25 mM Tris-HCl, pH 7.5, 5 mM beta-glycerophosphate, 2 mM dithio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Kronos Bio

US Patent
LigandPNGBDBM473072(N-[6-(1H-indazol-6- yl)imidazo[1,2- a]pyridin-8-yl...)
Affinity DataIC50:  3.80E+3nMAssay Description:A master mix minus Syk enzyme is prepared containing 1X Cell Signaling kinase buffer (25 mM Tris-HCl, pH 7.5, 5 mM beta-glycerophosphate, 2 mM dithio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Kronos Bio

US Patent
LigandPNGBDBM473108(1-(4-{6-[(6-{1H- pyrrolo[3,2-b]pyridin-6- yl}imida...)
Affinity DataIC50:  4.29E+3nMAssay Description:A master mix minus Syk enzyme is prepared containing 1X Cell Signaling kinase buffer (25 mM Tris-HCl, pH 7.5, 5 mM beta-glycerophosphate, 2 mM dithio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Kronos Bio

US Patent
LigandPNGBDBM473102(N-{4H,6H,7H- pyrazolo[3,2- c][1,4]oxazin-2-yl}-6- ...)
Affinity DataIC50:  4.50E+3nMAssay Description:A master mix minus Syk enzyme is prepared containing 1X Cell Signaling kinase buffer (25 mM Tris-HCl, pH 7.5, 5 mM beta-glycerophosphate, 2 mM dithio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Kronos Bio

US Patent
LigandPNGBDBM473092(N-[6-(1H-indazol-6- yl)imidazo[1,2- a]pyridin-8-yl...)
Affinity DataIC50:  5.00E+3nMAssay Description:A master mix minus Syk enzyme is prepared containing 1X Cell Signaling kinase buffer (25 mM Tris-HCl, pH 7.5, 5 mM beta-glycerophosphate, 2 mM dithio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Kronos Bio

US Patent
LigandPNGBDBM473095(1-(6-{[6-(1H-indazol-6- yl)imidazo[1,2- a]pyridin-...)
Affinity DataIC50:  5.00E+3nMAssay Description:A master mix minus Syk enzyme is prepared containing 1X Cell Signaling kinase buffer (25 mM Tris-HCl, pH 7.5, 5 mM beta-glycerophosphate, 2 mM dithio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Kronos Bio

US Patent
LigandPNGBDBM473100(US10842803, Structure TABLE 1.30 | [(2R)-4-(6-{[6-...)
Affinity DataIC50:  5.00E+3nMAssay Description:A master mix minus Syk enzyme is prepared containing 1X Cell Signaling kinase buffer (25 mM Tris-HCl, pH 7.5, 5 mM beta-glycerophosphate, 2 mM dithio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Kronos Bio

US Patent
LigandPNGBDBM473088(1-(6-{[6-(1H-indazol-6- yl)imidazo[1,2- a]pyridin-...)
Affinity DataIC50:  6.00E+3nMAssay Description:A master mix minus Syk enzyme is prepared containing 1X Cell Signaling kinase buffer (25 mM Tris-HCl, pH 7.5, 5 mM beta-glycerophosphate, 2 mM dithio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Kronos Bio

US Patent
LigandPNGBDBM473078(N-[6-(1H-indazol-6- yl)imidazo[1,2- a]pyridin-8-yl...)
Affinity DataIC50:  6.20E+3nMAssay Description:A master mix minus Syk enzyme is prepared containing 1X Cell Signaling kinase buffer (25 mM Tris-HCl, pH 7.5, 5 mM beta-glycerophosphate, 2 mM dithio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Kronos Bio

US Patent
LigandPNGBDBM473082(N-[6-(1H-indazol-6- yl)imidazo[1,2- a]pyridin-8-yl...)
Affinity DataIC50:  6.60E+3nMAssay Description:A master mix minus Syk enzyme is prepared containing 1X Cell Signaling kinase buffer (25 mM Tris-HCl, pH 7.5, 5 mM beta-glycerophosphate, 2 mM dithio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Kronos Bio

US Patent
LigandPNGBDBM473127(2-(6-(8-(6,7-dihydro-4H- pyrazolo[5,1- c][1,4]oxaz...)
Affinity DataIC50:  7.10E+3nMAssay Description:A master mix minus Syk enzyme is prepared containing 1X Cell Signaling kinase buffer (25 mM Tris-HCl, pH 7.5, 5 mM beta-glycerophosphate, 2 mM dithio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Kronos Bio

US Patent
LigandPNGBDBM473123(N-(5-methyl-6-(1H- pyrrolo[3,2-b]pyridin-6- yl)imi...)
Affinity DataIC50:  7.70E+3nMAssay Description:A master mix minus Syk enzyme is prepared containing 1X Cell Signaling kinase buffer (25 mM Tris-HCl, pH 7.5, 5 mM beta-glycerophosphate, 2 mM dithio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Kronos Bio

US Patent
LigandPNGBDBM473097(1-[(6-{[6-(1H-indazol-6- yl)imidazo[1,2- a]pyridin...)
Affinity DataIC50:  8.00E+3nMAssay Description:A master mix minus Syk enzyme is prepared containing 1X Cell Signaling kinase buffer (25 mM Tris-HCl, pH 7.5, 5 mM beta-glycerophosphate, 2 mM dithio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Kronos Bio

US Patent
LigandPNGBDBM473098(US10842803, Structure TABLE 1.28 | [(2S)-4-(6-{[6-...)
Affinity DataIC50:  8.00E+3nMAssay Description:A master mix minus Syk enzyme is prepared containing 1X Cell Signaling kinase buffer (25 mM Tris-HCl, pH 7.5, 5 mM beta-glycerophosphate, 2 mM dithio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Kronos Bio

US Patent
LigandPNGBDBM473107(2-[ethyl({6-[(6-{1H- pyrrolo[3,2-b]pyridin-6- yl}i...)
Affinity DataIC50:  8.50E+3nMAssay Description:A master mix minus Syk enzyme is prepared containing 1X Cell Signaling kinase buffer (25 mM Tris-HCl, pH 7.5, 5 mM beta-glycerophosphate, 2 mM dithio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Kronos Bio

US Patent
LigandPNGBDBM473089(2-[(6-{[6-(1H-indazol-6- yl)imidazo[1,2- a]pyridin...)
Affinity DataIC50:  9.00E+3nMAssay Description:A master mix minus Syk enzyme is prepared containing 1X Cell Signaling kinase buffer (25 mM Tris-HCl, pH 7.5, 5 mM beta-glycerophosphate, 2 mM dithio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Kronos Bio

US Patent
LigandPNGBDBM473117(6-[8-({5- methanesulfonyl- 4H,5H,6H,7H- pyrazolo[1...)
Affinity DataIC50:  1.00E+4nMAssay Description:A master mix minus Syk enzyme is prepared containing 1X Cell Signaling kinase buffer (25 mM Tris-HCl, pH 7.5, 5 mM beta-glycerophosphate, 2 mM dithio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Kronos Bio

US Patent
LigandPNGBDBM473105(1,5-dimethyl-N-(6-{1H- pyrrolo[3,2-b]pyridin-6- yl...)
Affinity DataIC50:  1.05E+4nMAssay Description:A master mix minus Syk enzyme is prepared containing 1X Cell Signaling kinase buffer (25 mM Tris-HCl, pH 7.5, 5 mM beta-glycerophosphate, 2 mM dithio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Kronos Bio

US Patent
LigandPNGBDBM473124(6-(8-(6,7-dihydro-4H- pyrazolo[5,1- c][1,4]oxazin-...)
Affinity DataIC50:  1.08E+4nMAssay Description:A master mix minus Syk enzyme is prepared containing 1X Cell Signaling kinase buffer (25 mM Tris-HCl, pH 7.5, 5 mM beta-glycerophosphate, 2 mM dithio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Kronos Bio

US Patent
LigandPNGBDBM473122(N-(5-(methoxymethyl)- 1-methyl-1H-pyrazol-3- yl)-6...)
Affinity DataIC50:  1.09E+4nMAssay Description:A master mix minus Syk enzyme is prepared containing 1X Cell Signaling kinase buffer (25 mM Tris-HCl, pH 7.5, 5 mM beta-glycerophosphate, 2 mM dithio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Kronos Bio

US Patent
LigandPNGBDBM473120(5-(4-ethylpiperazin-1- yl)-N-(6-{1H- pyrrolo[3,2-b...)
Affinity DataIC50:  1.13E+4nMAssay Description:A master mix minus Syk enzyme is prepared containing 1X Cell Signaling kinase buffer (25 mM Tris-HCl, pH 7.5, 5 mM beta-glycerophosphate, 2 mM dithio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Kronos Bio

US Patent
LigandPNGBDBM473162(5-(5-chloro-8-(5-(4- isopropylpiperazin-1- yl)pyri...)
Affinity DataIC50:  1.20E+4nMAssay Description:A master mix minus Syk enzyme is prepared containing 1X Cell Signaling kinase buffer (25 mM Tris-HCl, pH 7.5, 5 mM beta-glycerophosphate, 2 mM dithio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Kronos Bio

US Patent
LigandPNGBDBM473131(N-(6-(1H-indazol-6-yl)- 5-methylimidazo[1,2- a]pyr...)
Affinity DataIC50:  1.28E+4nMAssay Description:A master mix minus Syk enzyme is prepared containing 1X Cell Signaling kinase buffer (25 mM Tris-HCl, pH 7.5, 5 mM beta-glycerophosphate, 2 mM dithio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Kronos Bio

US Patent
LigandPNGBDBM473112(6-(8-{[5- (hydroxymethyl)-1- methyl-1H-pyrazol-3- ...)
Affinity DataIC50:  1.30E+4nMAssay Description:A master mix minus Syk enzyme is prepared containing 1X Cell Signaling kinase buffer (25 mM Tris-HCl, pH 7.5, 5 mM beta-glycerophosphate, 2 mM dithio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Kronos Bio

US Patent
LigandPNGBDBM473091(2-N-[6-(1H-indazol-6- yl)imidazo[1,2- a]pyridin-8-...)
Affinity DataIC50:  1.30E+4nMAssay Description:A master mix minus Syk enzyme is prepared containing 1X Cell Signaling kinase buffer (25 mM Tris-HCl, pH 7.5, 5 mM beta-glycerophosphate, 2 mM dithio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Kronos Bio

US Patent
LigandPNGBDBM473134(N-(6-(1H-indol-6- yl)imidazo[1,2- a]pyridin-8-yl)-...)
Affinity DataIC50:  1.30E+4nMAssay Description:A master mix minus Syk enzyme is prepared containing 1X Cell Signaling kinase buffer (25 mM Tris-HCl, pH 7.5, 5 mM beta-glycerophosphate, 2 mM dithio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Kronos Bio

US Patent
LigandPNGBDBM473076(6-{8-[(5,6- dimethoxypyridin-2- yl)amino]imidazo[1...)
Affinity DataIC50:  1.33E+4nMAssay Description:A master mix minus Syk enzyme is prepared containing 1X Cell Signaling kinase buffer (25 mM Tris-HCl, pH 7.5, 5 mM beta-glycerophosphate, 2 mM dithio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Kronos Bio

US Patent
LigandPNGBDBM473158(5-chloro-N-(5-(4- ethylpiperazin-1- yl)pyridin-2-y...)
Affinity DataIC50:  1.40E+4nMAssay Description:A master mix minus Syk enzyme is prepared containing 1X Cell Signaling kinase buffer (25 mM Tris-HCl, pH 7.5, 5 mM beta-glycerophosphate, 2 mM dithio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Kronos Bio

US Patent
LigandPNGBDBM473161(2-(6-(5-chloro-8-(5-(4- isopropylpiperazin-1- yl)p...)
Affinity DataIC50:  1.50E+4nMAssay Description:A master mix minus Syk enzyme is prepared containing 1X Cell Signaling kinase buffer (25 mM Tris-HCl, pH 7.5, 5 mM beta-glycerophosphate, 2 mM dithio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Kronos Bio

US Patent
LigandPNGBDBM473099(N-[6-(1H-indazol-6-yl)- 5-methylimidazo[1,2- a]pyr...)
Affinity DataIC50:  1.50E+4nMAssay Description:A master mix minus Syk enzyme is prepared containing 1X Cell Signaling kinase buffer (25 mM Tris-HCl, pH 7.5, 5 mM beta-glycerophosphate, 2 mM dithio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Kronos Bio

US Patent
LigandPNGBDBM473094(6-(8-{[6-(morpholin-4- yl)pyridazin-3- yl]amino}im...)
Affinity DataIC50:  1.50E+4nMAssay Description:A master mix minus Syk enzyme is prepared containing 1X Cell Signaling kinase buffer (25 mM Tris-HCl, pH 7.5, 5 mM beta-glycerophosphate, 2 mM dithio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Kronos Bio

US Patent
LigandPNGBDBM473119(6-(8-{[5-(4- acetylpiperazin-1- yl)pyridin-2- yl]a...)
Affinity DataIC50:  1.55E+4nMAssay Description:A master mix minus Syk enzyme is prepared containing 1X Cell Signaling kinase buffer (25 mM Tris-HCl, pH 7.5, 5 mM beta-glycerophosphate, 2 mM dithio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Kronos Bio

US Patent
LigandPNGBDBM473139(N-(5-(4-ethylpiperazin- 1-yl)pyridin-2-yl)-6- (1H-...)
Affinity DataIC50:  1.70E+4nMAssay Description:A master mix minus Syk enzyme is prepared containing 1X Cell Signaling kinase buffer (25 mM Tris-HCl, pH 7.5, 5 mM beta-glycerophosphate, 2 mM dithio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Kronos Bio

US Patent
LigandPNGBDBM473159(6-(5-chloro-8-(5-(4- isopropylpiperazin-1- yl)pyri...)
Affinity DataIC50:  1.70E+4nMAssay Description:A master mix minus Syk enzyme is prepared containing 1X Cell Signaling kinase buffer (25 mM Tris-HCl, pH 7.5, 5 mM beta-glycerophosphate, 2 mM dithio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Kronos Bio

US Patent
LigandPNGBDBM473138(2-(6-(8-(5- morpholinopyridin-2- ylamino)imidazo[1...)
Affinity DataIC50:  1.70E+4nMAssay Description:A master mix minus Syk enzyme is prepared containing 1X Cell Signaling kinase buffer (25 mM Tris-HCl, pH 7.5, 5 mM beta-glycerophosphate, 2 mM dithio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Kronos Bio

US Patent
LigandPNGBDBM473113(6-[8-({5-acetyl- 4H,5H,6H,7H- pyrazolo[1,5-a]pyraz...)
Affinity DataIC50:  1.80E+4nMAssay Description:A master mix minus Syk enzyme is prepared containing 1X Cell Signaling kinase buffer (25 mM Tris-HCl, pH 7.5, 5 mM beta-glycerophosphate, 2 mM dithio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Kronos Bio

US Patent
LigandPNGBDBM473074(N-[6-(1,3-benzothiazol- 5-yl)imidazo[1,2- a]pyridi...)
Affinity DataIC50:  1.82E+4nMAssay Description:A master mix minus Syk enzyme is prepared containing 1X Cell Signaling kinase buffer (25 mM Tris-HCl, pH 7.5, 5 mM beta-glycerophosphate, 2 mM dithio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Kronos Bio

US Patent
LigandPNGBDBM473136(6-(8-(5-(1-hydroxy-2- methylpropan-2- yl)pyridin-2...)
Affinity DataIC50:  1.90E+4nMAssay Description:A master mix minus Syk enzyme is prepared containing 1X Cell Signaling kinase buffer (25 mM Tris-HCl, pH 7.5, 5 mM beta-glycerophosphate, 2 mM dithio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Kronos Bio

US Patent
LigandPNGBDBM473128(5-(8-(5-(2- hydroxypropan-2-yl)-1- methyl-1H-pyraz...)
Affinity DataIC50:  1.97E+4nMAssay Description:A master mix minus Syk enzyme is prepared containing 1X Cell Signaling kinase buffer (25 mM Tris-HCl, pH 7.5, 5 mM beta-glycerophosphate, 2 mM dithio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Kronos Bio

US Patent
LigandPNGBDBM473096(1-(6-{[6-(1H-indazol-6- yl)imidazo[1,2- a]pyridin-...)
Affinity DataIC50:  2.00E+4nMAssay Description:A master mix minus Syk enzyme is prepared containing 1X Cell Signaling kinase buffer (25 mM Tris-HCl, pH 7.5, 5 mM beta-glycerophosphate, 2 mM dithio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Kronos Bio

US Patent
LigandPNGBDBM473116(US10842803, Structure TABLE 1.46 | {1-methyl-3-[(6...)
Affinity DataIC50:  2.08E+4nMAssay Description:A master mix minus Syk enzyme is prepared containing 1X Cell Signaling kinase buffer (25 mM Tris-HCl, pH 7.5, 5 mM beta-glycerophosphate, 2 mM dithio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Kronos Bio

US Patent
LigandPNGBDBM473135(N-(5-cyclopropyl-1H- pyrazol-3-yl)-6-(1H- indazol-...)
Affinity DataIC50:  2.20E+4nMAssay Description:A master mix minus Syk enzyme is prepared containing 1X Cell Signaling kinase buffer (25 mM Tris-HCl, pH 7.5, 5 mM beta-glycerophosphate, 2 mM dithio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Kronos Bio

US Patent
LigandPNGBDBM473075(7-{8-[(5,6- dimethoxypyridin-2- yl)amino]imidazo[1...)
Affinity DataIC50:  2.24E+4nMAssay Description:A master mix minus Syk enzyme is prepared containing 1X Cell Signaling kinase buffer (25 mM Tris-HCl, pH 7.5, 5 mM beta-glycerophosphate, 2 mM dithio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Kronos Bio

US Patent
LigandPNGBDBM473087(2-N-[6-(1H-indazol-6- yl)imidazo[1,2- a]pyridin-8-...)
Affinity DataIC50:  2.31E+4nMAssay Description:A master mix minus Syk enzyme is prepared containing 1X Cell Signaling kinase buffer (25 mM Tris-HCl, pH 7.5, 5 mM beta-glycerophosphate, 2 mM dithio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Kronos Bio

US Patent
LigandPNGBDBM473103(1-methyl-N-(6-{1H- pyrrolo[3,2-b]pyridin-6- yl}imi...)
Affinity DataIC50:  2.32E+4nMAssay Description:A master mix minus Syk enzyme is prepared containing 1X Cell Signaling kinase buffer (25 mM Tris-HCl, pH 7.5, 5 mM beta-glycerophosphate, 2 mM dithio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Kronos Bio

US Patent
LigandPNGBDBM473077(N-[6-(3,4-dihydro-2H- 1,4-benzoxazin-6- yl)imidazo...)
Affinity DataIC50:  2.37E+4nMAssay Description:A master mix minus Syk enzyme is prepared containing 1X Cell Signaling kinase buffer (25 mM Tris-HCl, pH 7.5, 5 mM beta-glycerophosphate, 2 mM dithio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Kronos Bio

US Patent
LigandPNGBDBM473121(2-(6-(8-(5- morpholinopyridin-2- ylamino)imidazo[1...)
Affinity DataIC50:  2.39E+4nMAssay Description:A master mix minus Syk enzyme is prepared containing 1X Cell Signaling kinase buffer (25 mM Tris-HCl, pH 7.5, 5 mM beta-glycerophosphate, 2 mM dithio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
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