Compile Data Set for Download or QSAR
maximum 50k data
Found 95 Enz. Inhib. hit(s) with all data for entry = 9578
TargetTyrosine-protein phosphatase non-receptor type 11 [E76K](Homo sapiens (Human))
Board Of Regents, The University Of Texas System

US Patent
LigandPNGBDBM384120(1-(3-(2,3- Dichlorophenyl)-1H- pyrazolo[3,4-b]- py...)
Affinity DataIC50:  2nMAssay Description:Recombinant full-length wild-type and E76K mutant human PTPN11 proteins were cloned, expressed (E. coli system), and isolated via a two-step purifica...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein phosphatase non-receptor type 11 [E76K](Homo sapiens (Human))
Board Of Regents, The University Of Texas System

US Patent
LigandPNGBDBM384163((R)-8-(3-(2-chloro-3- methoxyphenyl)-1H- pyrazolo[...)
Affinity DataIC50:  39nMAssay Description:Recombinant full-length wild-type and E76K mutant human PTPN11 proteins were cloned, expressed (E. coli system), and isolated via a two-step purifica...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein phosphatase non-receptor type 11 [E76K](Homo sapiens (Human))
Board Of Regents, The University Of Texas System

US Patent
LigandPNGBDBM384191((R)-8-(3-(3-Chloro-2-(methylamino)pyridin-4-yl)-1H...)
Affinity DataIC50:  43nMAssay Description:Recombinant full-length wild-type and E76K mutant human PTPN11 proteins were cloned, expressed (E. coli system), and isolated via a two-step purifica...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein phosphatase non-receptor type 11 [E76K](Homo sapiens (Human))
Board Of Regents, The University Of Texas System

US Patent
LigandPNGBDBM384147((1-(3-(4-Chloro-3-methoxyphenyl)-1H-pyrazolo[3,4-b...)
Affinity DataIC50:  72nMAssay Description:Recombinant full-length wild-type and E76K mutant human PTPN11 proteins were cloned, expressed (E. coli system), and isolated via a two-step purifica...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein phosphatase non-receptor type 11 [E76K](Homo sapiens (Human))
Board Of Regents, The University Of Texas System

US Patent
LigandPNGBDBM384152((S)-8-(3-(2,3-Dichlorophenyl)-1H-pyrazolo[3,4-b]py...)
Affinity DataIC50:  75nMAssay Description:Recombinant full-length wild-type and E76K mutant human PTPN11 proteins were cloned, expressed (E. coli system), and isolated via a two-step purifica...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein phosphatase non-receptor type 11 [E76K](Homo sapiens (Human))
Board Of Regents, The University Of Texas System

US Patent
LigandPNGBDBM384206((2S,4R)-4-Amino-8-(3-(2-amino-3-chloropyridin-4-yl...)
Affinity DataIC50:  75nMAssay Description:Recombinant full-length wild-type and E76K mutant human PTPN11 proteins were cloned, expressed (E. coli system), and isolated via a two-step purifica...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein phosphatase non-receptor type 11 [E76K](Homo sapiens (Human))
Board Of Regents, The University Of Texas System

US Patent
LigandPNGBDBM384141((1-(3-(2-chloro-3- methoxy phenyl)-1H- pyrazolo[3,...)
Affinity DataIC50:  80nMAssay Description:Recombinant full-length wild-type and E76K mutant human PTPN11 proteins were cloned, expressed (E. coli system), and isolated via a two-step purifica...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein phosphatase non-receptor type 11 [E76K](Homo sapiens (Human))
Board Of Regents, The University Of Texas System

US Patent
LigandPNGBDBM384207((1R)-8-[3-(2-amino- 3-chloropyridin-4- yl)-1H-pyra...)
Affinity DataIC50:  83nMAssay Description:Recombinant full-length wild-type and E76K mutant human PTPN11 proteins were cloned, expressed (E. coli system), and isolated via a two-step purifica...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein phosphatase non-receptor type 11 [E76K](Homo sapiens (Human))
Board Of Regents, The University Of Texas System

US Patent
LigandPNGBDBM384208((1R)-8-[3-(3-amino- 2-chlorophenyl)-1H- pyrazolo[3...)
Affinity DataIC50:  84nMAssay Description:Recombinant full-length wild-type and E76K mutant human PTPN11 proteins were cloned, expressed (E. coli system), and isolated via a two-step purifica...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein phosphatase non-receptor type 11 [E76K](Homo sapiens (Human))
Board Of Regents, The University Of Texas System

US Patent
LigandPNGBDBM475734(8-(3-(2,3-Dichlorophenyl)-1H-pyrazolo[3,4-b]pyrazi...)
Affinity DataIC50:  98nMAssay Description:Recombinant full-length wild-type and E76K mutant human PTPN11 proteins were cloned, expressed (E. coli system), and isolated via a two-step purifica...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein phosphatase non-receptor type 11 [E76K](Homo sapiens (Human))
Board Of Regents, The University Of Texas System

US Patent
LigandPNGBDBM384184(4-(6-(4-(Aminomethyl)-4-methylpiperidin-1-yl)-1H-p...)
Affinity DataIC50:  99nMAssay Description:Recombinant full-length wild-type and E76K mutant human PTPN11 proteins were cloned, expressed (E. coli system), and isolated via a two-step purifica...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein phosphatase non-receptor type 11 [E76K](Homo sapiens (Human))
Board Of Regents, The University Of Texas System

US Patent
LigandPNGBDBM384139((1-(3-(3-Chloro-2-fluorophenyl)-1H-pyrazolo[3,4-b]...)
Affinity DataIC50:  101nMAssay Description:Recombinant full-length wild-type and E76K mutant human PTPN11 proteins were cloned, expressed (E. coli system), and isolated via a two-step purifica...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein phosphatase non-receptor type 11 [E76K](Homo sapiens (Human))
Board Of Regents, The University Of Texas System

US Patent
LigandPNGBDBM384148((R)-8-(3-(4-chloro-3- methoxyphenyl)-1H- pyrazolo[...)
Affinity DataIC50:  102nMAssay Description:Recombinant full-length wild-type and E76K mutant human PTPN11 proteins were cloned, expressed (E. coli system), and isolated via a two-step purifica...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein phosphatase non-receptor type 11 [E76K](Homo sapiens (Human))
Board Of Regents, The University Of Texas System

US Patent
LigandPNGBDBM384170((4-Amino-1-(3-(2,3-dichlorophenyl)-1H-pyrazolo[3,4...)
Affinity DataIC50:  104nMAssay Description:Recombinant full-length wild-type and E76K mutant human PTPN11 proteins were cloned, expressed (E. coli system), and isolated via a two-step purifica...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein phosphatase non-receptor type 11 [E76K](Homo sapiens (Human))
Board Of Regents, The University Of Texas System

US Patent
LigandPNGBDBM384117(1-(3-(2,3-dichlorophenyl)-1H-pyrazolo[3,4-b]pyrazi...)
Affinity DataIC50:  110nMAssay Description:Recombinant full-length wild-type and E76K mutant human PTPN11 proteins were cloned, expressed (E. coli system), and isolated via a two-step purifica...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 11 [E76K](Homo sapiens (Human))
Board Of Regents, The University Of Texas System

US Patent
LigandPNGBDBM384131((R)-8-(3-(4-chloro- phenyl)-1H- pyrazolo[3,4-b]- p...)
Affinity DataIC50:  118nMAssay Description:Recombinant full-length wild-type and E76K mutant human PTPN11 proteins were cloned, expressed (E. coli system), and isolated via a two-step purifica...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein phosphatase non-receptor type 11 [E76K](Homo sapiens (Human))
Board Of Regents, The University Of Texas System

US Patent
LigandPNGBDBM384209(3-{6-[4-(amino- methyl)-4-methyl- piperidin-1-yl]-...)
Affinity DataIC50:  119nMAssay Description:Recombinant full-length wild-type and E76K mutant human PTPN11 proteins were cloned, expressed (E. coli system), and isolated via a two-step purifica...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein phosphatase non-receptor type 11 [E76K](Homo sapiens (Human))
Board Of Regents, The University Of Texas System

US Patent
LigandPNGBDBM384167((R)-8-(3-(2- chlorophenyl)-1H- pyrazolo[3,4-b]- py...)
Affinity DataIC50:  119nMAssay Description:Recombinant full-length wild-type and E76K mutant human PTPN11 proteins were cloned, expressed (E. coli system), and isolated via a two-step purifica...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein phosphatase non-receptor type 11 [E76K](Homo sapiens (Human))
Board Of Regents, The University Of Texas System

US Patent
LigandPNGBDBM384192(4-(6-(4-Amino-4-methylpiperidin-1-yl)-1H-pyrazolo[...)
Affinity DataIC50:  128nMAssay Description:Recombinant full-length wild-type and E76K mutant human PTPN11 proteins were cloned, expressed (E. coli system), and isolated via a two-step purifica...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetTyrosine-protein phosphatase non-receptor type 11 [E76K](Homo sapiens (Human))
Board Of Regents, The University Of Texas System

US Patent
LigandPNGBDBM384196((S)-8-(3-(2-Amino-3-chloropyridin-4-yl)-1H-pyrazol...)
Affinity DataIC50:  132nMAssay Description:Recombinant full-length wild-type and E76K mutant human PTPN11 proteins were cloned, expressed (E. coli system), and isolated via a two-step purifica...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein phosphatase non-receptor type 11 [E76K](Homo sapiens (Human))
Board Of Regents, The University Of Texas System

US Patent
LigandPNGBDBM384129(1-(3-(4-Chlorophenyl)-1H-pyrazolo[3,4-b]pyrazin-6-...)
Affinity DataIC50:  140nMAssay Description:Recombinant full-length wild-type and E76K mutant human PTPN11 proteins were cloned, expressed (E. coli system), and isolated via a two-step purifica...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein phosphatase non-receptor type 11 [E76K](Homo sapiens (Human))
Board Of Regents, The University Of Texas System

US Patent
LigandPNGBDBM384132(1-(3-(3,4-dichloro- phenyl)-1H- pyrazolo[3,4-b]- p...)
Affinity DataIC50:  141nMAssay Description:Recombinant full-length wild-type and E76K mutant human PTPN11 proteins were cloned, expressed (E. coli system), and isolated via a two-step purifica...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein phosphatase non-receptor type 11 [E76K](Homo sapiens (Human))
Board Of Regents, The University Of Texas System

US Patent
LigandPNGBDBM384142((1-(3-(3-chloro-2- methylphenyl)-1H- pyrazolo[3,4-...)
Affinity DataIC50:  142nMAssay Description:Recombinant full-length wild-type and E76K mutant human PTPN11 proteins were cloned, expressed (E. coli system), and isolated via a two-step purifica...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein phosphatase non-receptor type 11 [E76K](Homo sapiens (Human))
Board Of Regents, The University Of Texas System

US Patent
LigandPNGBDBM384162((R)-8-(3-(3-chloro-2- fluorophenyl)-1H- pyrazolo[3...)
Affinity DataIC50:  143nMAssay Description:Recombinant full-length wild-type and E76K mutant human PTPN11 proteins were cloned, expressed (E. coli system), and isolated via a two-step purifica...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein phosphatase non-receptor type 11 [E76K](Homo sapiens (Human))
Board Of Regents, The University Of Texas System

US Patent
LigandPNGBDBM384164((R)-8-(3-(3-chloro-2- methylphenyl)-1H- pyrazolo[3...)
Affinity DataIC50:  153nMAssay Description:Recombinant full-length wild-type and E76K mutant human PTPN11 proteins were cloned, expressed (E. coli system), and isolated via a two-step purifica...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein phosphatase non-receptor type 11 [E76K](Homo sapiens (Human))
Board Of Regents, The University Of Texas System

US Patent
LigandPNGBDBM384153((S)-8-(3-(2-chloro- phenyl)-1H- pyrazolo[3,4-b]- p...)
Affinity DataIC50:  158nMAssay Description:Recombinant full-length wild-type and E76K mutant human PTPN11 proteins were cloned, expressed (E. coli system), and isolated via a two-step purifica...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein phosphatase non-receptor type 11 [E76K](Homo sapiens (Human))
Board Of Regents, The University Of Texas System

US Patent
LigandPNGBDBM384127((1-(3-(3,4-dichloro- phenyl)-1H- pyrazolo[3,4-b]- ...)
Affinity DataIC50:  158nMAssay Description:Recombinant full-length wild-type and E76K mutant human PTPN11 proteins were cloned, expressed (E. coli system), and isolated via a two-step purifica...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein phosphatase non-receptor type 11 [E76K](Homo sapiens (Human))
Board Of Regents, The University Of Texas System

US Patent
LigandPNGBDBM384187(4-(6-(4-(Aminomethyl)-4-methylpiperidin-1-yl)-1H-p...)
Affinity DataIC50:  162nMAssay Description:Recombinant full-length wild-type and E76K mutant human PTPN11 proteins were cloned, expressed (E. coli system), and isolated via a two-step purifica...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein phosphatase non-receptor type 11 [E76K](Homo sapiens (Human))
Board Of Regents, The University Of Texas System

US Patent
LigandPNGBDBM384130((1-(3-(4-chloro- phenyl)-1H- pyrazolo[3,4-b]- pyra...)
Affinity DataIC50:  169nMAssay Description:Recombinant full-length wild-type and E76K mutant human PTPN11 proteins were cloned, expressed (E. coli system), and isolated via a two-step purifica...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein phosphatase non-receptor type 11 [E76K](Homo sapiens (Human))
Board Of Regents, The University Of Texas System

US Patent
LigandPNGBDBM384143((1-(3-(2-chloro- phenyl)-1H- pyrazolo[3,4-b]- pyra...)
Affinity DataIC50:  178nMAssay Description:Recombinant full-length wild-type and E76K mutant human PTPN11 proteins were cloned, expressed (E. coli system), and isolated via a two-step purifica...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein phosphatase non-receptor type 11 [E76K](Homo sapiens (Human))
Board Of Regents, The University Of Texas System

US Patent
LigandPNGBDBM475750(US10851110, Example 113a)
Affinity DataIC50:  180nMAssay Description:Recombinant full-length wild-type and E76K mutant human PTPN11 proteins were cloned, expressed (E. coli system), and isolated via a two-step purifica...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein phosphatase non-receptor type 11 [E76K](Homo sapiens (Human))
Board Of Regents, The University Of Texas System

US Patent
LigandPNGBDBM384185(1-(3-(3-amino-2-chlorophenyl)-1H-pyrazolo[3,4-b]py...)
Affinity DataIC50:  191nMAssay Description:Recombinant full-length wild-type and E76K mutant human PTPN11 proteins were cloned, expressed (E. coli system), and isolated via a two-step purifica...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein phosphatase non-receptor type 11 [E76K](Homo sapiens (Human))
Board Of Regents, The University Of Texas System

US Patent
LigandPNGBDBM384159((R)-8-(3-(3,4-dichloro- phenyl)-1H- pyrazolo[3,4-b...)
Affinity DataIC50:  193nMAssay Description:Recombinant full-length wild-type and E76K mutant human PTPN11 proteins were cloned, expressed (E. coli system), and isolated via a two-step purifica...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein phosphatase non-receptor type 11 [E76K](Homo sapiens (Human))
Board Of Regents, The University Of Texas System

US Patent
LigandPNGBDBM384121(3-(2,3-dichloro- phenyl)-6-(1,7-diaza- spiro[3.5]n...)
Affinity DataIC50:  196nMAssay Description:Recombinant full-length wild-type and E76K mutant human PTPN11 proteins were cloned, expressed (E. coli system), and isolated via a two-step purifica...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein phosphatase non-receptor type 11 [E76K](Homo sapiens (Human))
Board Of Regents, The University Of Texas System

US Patent
LigandPNGBDBM384154((4S)-8-(3-(2-Chloro- 6-fluorophenyl)-1H- pyrazolo[...)
Affinity DataIC50:  203nMAssay Description:Recombinant full-length wild-type and E76K mutant human PTPN11 proteins were cloned, expressed (E. coli system), and isolated via a two-step purifica...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein phosphatase non-receptor type 11 [E76K](Homo sapiens (Human))
Board Of Regents, The University Of Texas System

US Patent
LigandPNGBDBM384138(1-(3-(2-chloro-3- fluorophenyl)-1H- pyrazolo[3,4-b...)
Affinity DataIC50:  204nMAssay Description:Recombinant full-length wild-type and E76K mutant human PTPN11 proteins were cloned, expressed (E. coli system), and isolated via a two-step purifica...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein phosphatase non-receptor type 11 [E76K](Homo sapiens (Human))
Board Of Regents, The University Of Texas System

US Patent
LigandPNGBDBM384122(4-(aminomethyl)-1- (3-(2,3-dichloro- phenyl)-1H- p...)
Affinity DataIC50:  204nMAssay Description:Recombinant full-length wild-type and E76K mutant human PTPN11 proteins were cloned, expressed (E. coli system), and isolated via a two-step purifica...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein phosphatase non-receptor type 11 [E76K](Homo sapiens (Human))
Board Of Regents, The University Of Texas System

US Patent
LigandPNGBDBM475759(3-(2,3-Dichlorophenyl)-6-(2,8-diazaspiro[4.5]decan...)
Affinity DataIC50:  205nMAssay Description:Recombinant full-length wild-type and E76K mutant human PTPN11 proteins were cloned, expressed (E. coli system), and isolated via a two-step purifica...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein phosphatase non-receptor type 11 [E76K](Homo sapiens (Human))
Board Of Regents, The University Of Texas System

US Patent
LigandPNGBDBM384140(1-(3-(3-chloro-2- fluorophenyl)-1H- pyrazolo[3,4-b...)
Affinity DataIC50:  213nMAssay Description:Recombinant full-length wild-type and E76K mutant human PTPN11 proteins were cloned, expressed (E. coli system), and isolated via a two-step purifica...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetTyrosine-protein phosphatase non-receptor type 11 [E76K](Homo sapiens (Human))
Board Of Regents, The University Of Texas System

US Patent
LigandPNGBDBM475735(US10851110, Example 64B | US11466017, Example 64B)
Affinity DataIC50:  221nMAssay Description:Recombinant full-length wild-type and E76K mutant human PTPN11 proteins were cloned, expressed (E. coli system), and isolated via a two-step purifica...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein phosphatase non-receptor type 11 [E76K](Homo sapiens (Human))
Board Of Regents, The University Of Texas System

US Patent
LigandPNGBDBM475736(8-(3-(2,3-Dichlorophenyl)-1H-pyrazolo[3,4-b]pyrazi...)
Affinity DataIC50:  235nMAssay Description:Recombinant full-length wild-type and E76K mutant human PTPN11 proteins were cloned, expressed (E. coli system), and isolated via a two-step purifica...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein phosphatase non-receptor type 11 [E76K](Homo sapiens (Human))
Board Of Regents, The University Of Texas System

US Patent
LigandPNGBDBM384186(4-(6-(4-Amino-4-methylpiperidin-1-yl)-1H-pyrazolo[...)
Affinity DataIC50:  253nMAssay Description:Recombinant full-length wild-type and E76K mutant human PTPN11 proteins were cloned, expressed (E. coli system), and isolated via a two-step purifica...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein phosphatase non-receptor type 11 [E76K](Homo sapiens (Human))
Board Of Regents, The University Of Texas System

US Patent
LigandPNGBDBM384149((1-(3-(3-chloro-5- methoxyphenyl)-1H- pyrazolo[3,4...)
Affinity DataIC50:  304nMAssay Description:Recombinant full-length wild-type and E76K mutant human PTPN11 proteins were cloned, expressed (E. coli system), and isolated via a two-step purifica...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein phosphatase non-receptor type 11 [E76K](Homo sapiens (Human))
Board Of Regents, The University Of Texas System

US Patent
LigandPNGBDBM384165((R)-8-(3-(3-chloro-5- methoxyphenyl)-1H- pyrazolo[...)
Affinity DataIC50:  313nMAssay Description:Recombinant full-length wild-type and E76K mutant human PTPN11 proteins were cloned, expressed (E. coli system), and isolated via a two-step purifica...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein phosphatase non-receptor type 11 [E76K](Homo sapiens (Human))
Board Of Regents, The University Of Texas System

US Patent
LigandPNGBDBM384134(1-(3-(2- Chlorophenyl)-1H- pyrazolo[3,4- b]pyrazin...)
Affinity DataIC50:  326nMAssay Description:Recombinant full-length wild-type and E76K mutant human PTPN11 proteins were cloned, expressed (E. coli system), and isolated via a two-step purifica...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein phosphatase non-receptor type 11 [E76K](Homo sapiens (Human))
Board Of Regents, The University Of Texas System

US Patent
LigandPNGBDBM384124(1-(3-(3-chloro- phenyl)-1H- pyrazolo[3,4-b]- pyraz...)
Affinity DataIC50:  333nMAssay Description:Recombinant full-length wild-type and E76K mutant human PTPN11 proteins were cloned, expressed (E. coli system), and isolated via a two-step purifica...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein phosphatase non-receptor type 11 [E76K](Homo sapiens (Human))
Board Of Regents, The University Of Texas System

US Patent
LigandPNGBDBM384171(1-(3-(2,3-dichlo- rophenyl)-1H- pyrazolo[3,4-b]- p...)
Affinity DataIC50:  338nMAssay Description:Recombinant full-length wild-type and E76K mutant human PTPN11 proteins were cloned, expressed (E. coli system), and isolated via a two-step purifica...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein phosphatase non-receptor type 11 [E76K](Homo sapiens (Human))
Board Of Regents, The University Of Texas System

US Patent
LigandPNGBDBM384158((R)-8-(3-(3,5-dichloro- phenyl)-1H- pyrazolo[3,4-b...)
Affinity DataIC50:  355nMAssay Description:Recombinant full-length wild-type and E76K mutant human PTPN11 proteins were cloned, expressed (E. coli system), and isolated via a two-step purifica...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein phosphatase non-receptor type 11 [E76K](Homo sapiens (Human))
Board Of Regents, The University Of Texas System

US Patent
LigandPNGBDBM384123((1-(3-(3-chloro- phenyl)-1H- pyrazolo[3,4-b]- pyra...)
Affinity DataIC50:  367nMAssay Description:Recombinant full-length wild-type and E76K mutant human PTPN11 proteins were cloned, expressed (E. coli system), and isolated via a two-step purifica...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein phosphatase non-receptor type 11 [E76K](Homo sapiens (Human))
Board Of Regents, The University Of Texas System

US Patent
LigandPNGBDBM384204(4-(6-(4-(Aminomethyl)-4-methylpiperidin-1-yl)-1H-p...)
Affinity DataIC50:  377nMAssay Description:Recombinant full-length wild-type and E76K mutant human PTPN11 proteins were cloned, expressed (E. coli system), and isolated via a two-step purifica...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
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