Compile Data Set for Download or QSAR
maximum 50k data
Found 71 Enz. Inhib. hit(s) with all data for entry = 9560
TargetPolymerase acidic protein()
Novartis

US Patent
LigandPNGBDBM474361((S)-6-benzhydryl-11-hydroxy-3-(1H-pyrazol- 4-yl)-5...)
Affinity DataIC50:  8nMAssay Description:Compounds were dissolved and serially diluted in 100% DMSO then 0.5 μl was transferred to 384-well plates. 50 nM truncated Influenza A/victoria/...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPolymerase acidic protein()
Novartis

US Patent
LigandPNGBDBM474354((S)-6-((S)-(3-fluorophenyl)(4- fluorophenyl)methyl...)
Affinity DataIC50:  9nMAssay Description:Compounds were dissolved and serially diluted in 100% DMSO then 0.5 μl was transferred to 384-well plates. 50 nM truncated Influenza A/victoria/...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPolymerase acidic protein()
Novartis

US Patent
LigandPNGBDBM474346((S)-6-benzhydryl-3-bromo-11-hydroxy-5H- imidazo[1,...)
Affinity DataIC50:  9nMAssay Description:Compounds were dissolved and serially diluted in 100% DMSO then 0.5 μl was transferred to 384-well plates. 50 nM truncated Influenza A/victoria/...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPolymerase acidic protein()
Novartis

US Patent
LigandPNGBDBM474343((S)-6-Benzhydryl-11-hydroxy-5H- imidazo[1,2-a]pyri...)
Affinity DataIC50:  10nMAssay Description:Compounds were dissolved and serially diluted in 100% DMSO then 0.5 μl was transferred to 384-well plates. 50 nM truncated Influenza A/victoria/...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPolymerase acidic protein()
Novartis

US Patent
LigandPNGBDBM474367((S)-6-((S)-(3-bromophenyl)(4- fluorophenyl)methyl)...)
Affinity DataIC50:  10nMAssay Description:Compounds were dissolved and serially diluted in 100% DMSO then 0.5 μl was transferred to 384-well plates. 50 nM truncated Influenza A/victoria/...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPolymerase acidic protein()
Novartis

US Patent
LigandPNGBDBM474357((S)-6-((R)-(2-bromo-4-fluorophenyl)(4- fluoropheny...)
Affinity DataIC50:  10nMAssay Description:Compounds were dissolved and serially diluted in 100% DMSO then 0.5 μl was transferred to 384-well plates. 50 nM truncated Influenza A/victoria/...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPolymerase acidic protein()
Novartis

US Patent
LigandPNGBDBM474355((S)-6-((S)-(4-chlorophenyl)(4- fluorophenyl)methyl...)
Affinity DataIC50:  20nMAssay Description:Compounds were dissolved and serially diluted in 100% DMSO then 0.5 μl was transferred to 384-well plates. 50 nM truncated Influenza A/victoria/...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPolymerase acidic protein()
Novartis

US Patent
LigandPNGBDBM474344((S)-6-Benzhydryl-3-chloro-11-hydroxy-5,6- dihydro-...)
Affinity DataIC50:  20nMAssay Description:Compounds were dissolved and serially diluted in 100% DMSO then 0.5 μl was transferred to 384-well plates. 50 nM truncated Influenza A/victoria/...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPolymerase acidic protein()
Novartis

US Patent
LigandPNGBDBM474358((S)-6-((S)-(4-fluorophenyl)(o-tolyl)methyl)-11- hy...)
Affinity DataIC50:  20nMAssay Description:Compounds were dissolved and serially diluted in 100% DMSO then 0.5 μl was transferred to 384-well plates. 50 nM truncated Influenza A/victoria/...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPolymerase acidic protein()
Novartis

US Patent
LigandPNGBDBM474349((S)-6-((R)-(4-fluorophenyl)(phenyl)methyl)- 11-hyd...)
Affinity DataIC50:  20nMAssay Description:Compounds were dissolved and serially diluted in 100% DMSO then 0.5 μl was transferred to 384-well plates. 50 nM truncated Influenza A/victoria/...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPolymerase acidic protein()
Novartis

US Patent
LigandPNGBDBM474350((S)-6-((S)-(4-fluorophenyl)(phenyl)methyl)- 11-hyd...)
Affinity DataIC50:  20nMAssay Description:Compounds were dissolved and serially diluted in 100% DMSO then 0.5 μl was transferred to 384-well plates. 50 nM truncated Influenza A/victoria/...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPolymerase acidic protein()
Novartis

US Patent
LigandPNGBDBM474359(3-((S)-(4-fluorophenyl)((S)-11-hydroxy-10- oxo-5,6...)
Affinity DataIC50:  20nMAssay Description:Compounds were dissolved and serially diluted in 100% DMSO then 0.5 μl was transferred to 384-well plates. 50 nM truncated Influenza A/victoria/...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPolymerase acidic protein()
Novartis

US Patent
LigandPNGBDBM474351((S)-6-((R)-(4-fluorophenyl)(5-fluoropyridin-3- yl)...)
Affinity DataIC50:  40nMAssay Description:Compounds were dissolved and serially diluted in 100% DMSO then 0.5 μl was transferred to 384-well plates. 50 nM truncated Influenza A/victoria/...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPolymerase acidic protein()
Novartis

US Patent
LigandPNGBDBM474347((S)-6-benzhydryl-3-cyclopropyl-11-hydroxy- 5H-imid...)
Affinity DataIC50:  40nMAssay Description:Compounds were dissolved and serially diluted in 100% DMSO then 0.5 μl was transferred to 384-well plates. 50 nM truncated Influenza A/victoria/...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPolymerase acidic protein()
Novartis

US Patent
LigandPNGBDBM474345(6-benzhydryl-11-hydroxy-5,6-dihydro-10H- imidazo[1...)
Affinity DataIC50:  40nMAssay Description:Compounds were dissolved and serially diluted in 100% DMSO then 0.5 μl was transferred to 384-well plates. 50 nM truncated Influenza A/victoria/...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPolymerase acidic protein()
Novartis

US Patent
LigandPNGBDBM474366(6-benzhydryl-5-ethyl-11-hydroxy-5,6-dihydro- 10H-i...)
Affinity DataIC50:  40nMAssay Description:Compounds were dissolved and serially diluted in 100% DMSO then 0.5 μl was transferred to 384-well plates. 50 nM truncated Influenza A/victoria/...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPolymerase acidic protein()
Novartis

US Patent
LigandPNGBDBM474364((S)-6-benzhydryl-3-(difluoromethyl)-11- hydroxy-5,...)
Affinity DataIC50:  40nMAssay Description:Compounds were dissolved and serially diluted in 100% DMSO then 0.5 μl was transferred to 384-well plates. 50 nM truncated Influenza A/victoria/...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPolymerase acidic protein()
Novartis

US Patent
LigandPNGBDBM474356((S)-6-((S)-(4-fluorophenyl)(m-tolyl)methyl)- 11-hy...)
Affinity DataIC50:  40nMAssay Description:Compounds were dissolved and serially diluted in 100% DMSO then 0.5 μl was transferred to 384-well plates. 50 nM truncated Influenza A/victoria/...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPolymerase acidic protein()
Novartis

US Patent
LigandPNGBDBM474360(3-((R)-(3-fluorophenyl)((S)-11-hydroxy-10- oxo-5,6...)
Affinity DataIC50:  50nMAssay Description:Compounds were dissolved and serially diluted in 100% DMSO then 0.5 μl was transferred to 384-well plates. 50 nM truncated Influenza A/victoria/...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPolymerase acidic protein()
Novartis

US Patent
LigandPNGBDBM474353((S)-6-(bis(3-fluorophenyl)methyl)-11- hydroxy-5,6-...)
Affinity DataIC50:  50nMAssay Description:Compounds were dissolved and serially diluted in 100% DMSO then 0.5 μl was transferred to 384-well plates. 50 nM truncated Influenza A/victoria/...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPolymerase acidic protein()
Novartis

US Patent
LigandPNGBDBM474340(6-Benzhydryl-11-hydroxy-5H- imidazo[2',1':3,4]pyra...)
Affinity DataIC50:  50nMAssay Description:Compounds were dissolved and serially diluted in 100% DMSO then 0.5 μl was transferred to 384-well plates. 50 nM truncated Influenza A/victoria/...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPolymerase acidic protein()
Novartis

US Patent
LigandPNGBDBM474362((S)-6-benzhydryl-11-hydroxy-3-phenyl-5,6- dihydro-...)
Affinity DataIC50:  60nMAssay Description:Compounds were dissolved and serially diluted in 100% DMSO then 0.5 μl was transferred to 384-well plates. 50 nM truncated Influenza A/victoria/...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPolymerase acidic protein()
Novartis

US Patent
LigandPNGBDBM474341(6-(bis(3-fluorophenyl)methyl)-11-hydroxy- 5,6-dihy...)
Affinity DataIC50:  70nMAssay Description:Compounds were dissolved and serially diluted in 100% DMSO then 0.5 μl was transferred to 384-well plates. 50 nM truncated Influenza A/victoria/...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPolymerase acidic protein()
Novartis

US Patent
LigandPNGBDBM474365(6-benzhydryl-11-hydroxy-5,5-dimethyl-5,6- dihydro-...)
Affinity DataIC50:  100nMAssay Description:Compounds were dissolved and serially diluted in 100% DMSO then 0.5 μl was transferred to 384-well plates. 50 nM truncated Influenza A/victoria/...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPolymerase acidic protein()
Novartis

US Patent
LigandPNGBDBM474369((S)-6-benzhydryl-11-hydroxy-3- (hydroxymethyl)-5,6...)
Affinity DataIC50:  100nMAssay Description:Compounds were dissolved and serially diluted in 100% DMSO then 0.5 μl was transferred to 384-well plates. 50 nM truncated Influenza A/victoria/...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPolymerase acidic protein()
Novartis

US Patent
LigandPNGBDBM474348((S)-6-benzhydryl-11-hydroxy-2,3-dimethyl- 5H-imida...)
Affinity DataIC50:  100nMAssay Description:Compounds were dissolved and serially diluted in 100% DMSO then 0.5 μl was transferred to 384-well plates. 50 nM truncated Influenza A/victoria/...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPolymerase acidic protein()
Novartis

US Patent
LigandPNGBDBM474363((S)-6-benzhydryl-11-hydroxy-3- (methoxymethyl)-5,6...)
Affinity DataIC50:  100nMAssay Description:Compounds were dissolved and serially diluted in 100% DMSO then 0.5 μl was transferred to 384-well plates. 50 nM truncated Influenza A/victoria/...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPolymerase acidic protein()
Novartis

US Patent
LigandPNGBDBM474352((S)-6-((R)-(4-fluorophenyl)(6- (trifluoromethyl)py...)
Affinity DataIC50:  300nMAssay Description:Compounds were dissolved and serially diluted in 100% DMSO then 0.5 μl was transferred to 384-well plates. 50 nM truncated Influenza A/victoria/...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPolymerase acidic protein()
Novartis

US Patent
LigandPNGBDBM474342(6-benzhydryl-11-hydroxy-5,6-dihydro-10H- [1,2,4]tr...)
Affinity DataIC50:  400nMAssay Description:Compounds were dissolved and serially diluted in 100% DMSO then 0.5 μl was transferred to 384-well plates. 50 nM truncated Influenza A/victoria/...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNeuraminidase(Influenza A virus (strain A/Wilson-Smith/1933 H1N1...)
Novartis

US Patent
LigandPNGBDBM474367((S)-6-((S)-(3-bromophenyl)(4- fluorophenyl)methyl)...)
Affinity DataEC50:  45nMAssay Description:For influenza NA assays, MDCK cells were plated in Phenol Red-free DMEM (Gibco) supplemented with 2 mM L-Glutamine, 1% sodium pyruvate (Cellgro, Mana...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNeuraminidase(Influenza A virus (strain A/Memphis/1/1971 H3N2))
Novartis

US Patent
LigandPNGBDBM474367((S)-6-((S)-(3-bromophenyl)(4- fluorophenyl)methyl)...)
Affinity DataEC50:  190nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNeuraminidase()
Novartis

US Patent
LigandPNGBDBM474367((S)-6-((S)-(3-bromophenyl)(4- fluorophenyl)methyl)...)
Affinity DataEC50:  65nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNeuraminidase(Influenza A virus (strain A/Wilson-Smith/1933 H1N1...)
Novartis

US Patent
LigandPNGBDBM474368((S)-6-(bis(4-fluorophenyl)methyl)-3-bromo- 11-hydr...)
Affinity DataEC50:  290nMAssay Description:For influenza NA assays, MDCK cells were plated in Phenol Red-free DMEM (Gibco) supplemented with 2 mM L-Glutamine, 1% sodium pyruvate (Cellgro, Mana...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNeuraminidase(Influenza A virus (strain A/Memphis/1/1971 H3N2))
Novartis

US Patent
LigandPNGBDBM474368((S)-6-(bis(4-fluorophenyl)methyl)-3-bromo- 11-hydr...)
Affinity DataEC50:  840nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNeuraminidase()
Novartis

US Patent
LigandPNGBDBM474368((S)-6-(bis(4-fluorophenyl)methyl)-3-bromo- 11-hydr...)
Affinity DataEC50:  560nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNeuraminidase(Influenza A virus (strain A/Wilson-Smith/1933 H1N1...)
Novartis

US Patent
LigandPNGBDBM474369((S)-6-benzhydryl-11-hydroxy-3- (hydroxymethyl)-5,6...)
Affinity DataEC50:  2.60E+3nMAssay Description:For influenza NA assays, MDCK cells were plated in Phenol Red-free DMEM (Gibco) supplemented with 2 mM L-Glutamine, 1% sodium pyruvate (Cellgro, Mana...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNeuraminidase(Influenza A virus (strain A/Memphis/1/1971 H3N2))
Novartis

US Patent
LigandPNGBDBM474369((S)-6-benzhydryl-11-hydroxy-3- (hydroxymethyl)-5,6...)
Affinity DataEC50:  4.60E+3nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNeuraminidase()
Novartis

US Patent
LigandPNGBDBM474369((S)-6-benzhydryl-11-hydroxy-3- (hydroxymethyl)-5,6...)
Affinity DataEC50:  1.60E+3nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNeuraminidase(Influenza A virus (strain A/Wilson-Smith/1933 H1N1...)
Novartis

US Patent
LigandPNGBDBM474370((S)-6-benzhydryl-11-hydroxy-3- (trifluoromethyl)-5...)
Affinity DataEC50:  200nMAssay Description:For influenza NA assays, MDCK cells were plated in Phenol Red-free DMEM (Gibco) supplemented with 2 mM L-Glutamine, 1% sodium pyruvate (Cellgro, Mana...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNeuraminidase(Influenza A virus (strain A/Memphis/1/1971 H3N2))
Novartis

US Patent
LigandPNGBDBM474370((S)-6-benzhydryl-11-hydroxy-3- (trifluoromethyl)-5...)
Affinity DataEC50:  1.80E+3nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNeuraminidase()
Novartis

US Patent
LigandPNGBDBM474370((S)-6-benzhydryl-11-hydroxy-3- (trifluoromethyl)-5...)
Affinity DataEC50:  820nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNeuraminidase(Influenza A virus (strain A/Wilson-Smith/1933 H1N1...)
Novartis

US Patent
LigandPNGBDBM474371((S)-6-benzhydryl-11-hydroxy-10-oxo-5,6- dihydro-10...)
Affinity DataEC50:  1.40E+3nMAssay Description:For influenza NA assays, MDCK cells were plated in Phenol Red-free DMEM (Gibco) supplemented with 2 mM L-Glutamine, 1% sodium pyruvate (Cellgro, Mana...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNeuraminidase(Influenza A virus (strain A/Memphis/1/1971 H3N2))
Novartis

US Patent
LigandPNGBDBM474371((S)-6-benzhydryl-11-hydroxy-10-oxo-5,6- dihydro-10...)
Affinity DataEC50:  5.70E+3nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNeuraminidase()
Novartis

US Patent
LigandPNGBDBM474371((S)-6-benzhydryl-11-hydroxy-10-oxo-5,6- dihydro-10...)
Affinity DataEC50:  1.20E+3nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNeuraminidase(Influenza A virus (strain A/Wilson-Smith/1933 H1N1...)
Novartis

US Patent
LigandPNGBDBM474372((S)-6-benzhydryl-11-hydroxy-3- ((methylamino)methy...)
Affinity DataEC50:  2.30E+3nMAssay Description:For influenza NA assays, MDCK cells were plated in Phenol Red-free DMEM (Gibco) supplemented with 2 mM L-Glutamine, 1% sodium pyruvate (Cellgro, Mana...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNeuraminidase(Influenza A virus (strain A/Memphis/1/1971 H3N2))
Novartis

US Patent
LigandPNGBDBM474372((S)-6-benzhydryl-11-hydroxy-3- ((methylamino)methy...)
Affinity DataEC50:  5.70E+3nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNeuraminidase()
Novartis

US Patent
LigandPNGBDBM474372((S)-6-benzhydryl-11-hydroxy-3- ((methylamino)methy...)
Affinity DataEC50:  3.40E+3nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNeuraminidase(Influenza A virus (strain A/Wilson-Smith/1933 H1N1...)
Novartis

US Patent
LigandPNGBDBM474373((S)-6-benzhydryl-3- ((cyclohexylamino)methyl)-11-h...)
Affinity DataEC50:  3.20E+3nMAssay Description:For influenza NA assays, MDCK cells were plated in Phenol Red-free DMEM (Gibco) supplemented with 2 mM L-Glutamine, 1% sodium pyruvate (Cellgro, Mana...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNeuraminidase(Influenza A virus (strain A/Memphis/1/1971 H3N2))
Novartis

US Patent
LigandPNGBDBM474373((S)-6-benzhydryl-3- ((cyclohexylamino)methyl)-11-h...)
Affinity DataEC50:  6.10E+3nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNeuraminidase()
Novartis

US Patent
LigandPNGBDBM474373((S)-6-benzhydryl-3- ((cyclohexylamino)methyl)-11-h...)
Affinity DataEC50:  3.90E+3nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
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