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Patent code US10889546

Compile Data Set for Download or QSAR
Found 85 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Egl nine homolog 1


(Homo sapiens (Human))
BDBM50318679
PNG
(CHEMBL4162752 | US10889546, Example 44)
Show SMILES OC(=O)CNC(=O)c1ncc(cc1O)C#CCOc1ccc(Cl)cc1
Show InChI InChI=1S/C17H13ClN2O5/c18-12-3-5-13(6-4-12)25-7-1-2-11-8-14(21)16(19-9-11)17(24)20-10-15(22)23/h3-6,8-9,21H,7,10H2,(H,20,24)(H,22,23)
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Similars

US Patent
n/an/a 13.7n/an/an/an/an/an/a



Jiangsu Hengrui Medicine Co., Ltd.

US Patent


Assay Description
The EGLN-1 (or EGLN-3) enzyme activity is determined using mass spectrometry (matrix-assisted laser desorption ionization, time-of-flight MS, MALD...


US Patent US10889546 (2021)

More data for this
Ligand-Target Pair
Egl nine homolog 1


(Homo sapiens (Human))
BDBM477226
PNG
(US10889546, Example 35)
Show SMILES Cc1ccccc1OCC#Cc1cnc(C(=O)NCC(O)=O)c(O)c1
Show InChI InChI=1S/C18H16N2O5/c1-12-5-2-3-7-15(12)25-8-4-6-13-9-14(21)17(19-10-13)18(24)20-11-16(22)23/h2-3,5,7,9-10,21H,8,11H2,1H3,(H,20,24)(H,22,23)
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n/an/a 70.4n/an/an/an/an/an/a



Jiangsu Hengrui Medicine Co., Ltd.

US Patent


Assay Description
The EGLN-1 (or EGLN-3) enzyme activity is determined using mass spectrometry (matrix-assisted laser desorption ionization, time-of-flight MS, MALD...


US Patent US10889546 (2021)

More data for this
Ligand-Target Pair
Egl nine homolog 1


(Homo sapiens (Human))
BDBM477229
PNG
(US10889546, Example 38)
Show SMILES Cc1cccc(OCC#Cc2cnc(C(=O)NCC(O)=O)c(O)c2)c1C
Show InChI InChI=1S/C19H18N2O5/c1-12-5-3-7-16(13(12)2)26-8-4-6-14-9-15(22)18(20-10-14)19(25)21-11-17(23)24/h3,5,7,9-10,22H,8,11H2,1-2H3,(H,21,25)(H,23,24)
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n/an/a 79.2n/an/an/an/an/an/a



Jiangsu Hengrui Medicine Co., Ltd.

US Patent


Assay Description
The EGLN-1 (or EGLN-3) enzyme activity is determined using mass spectrometry (matrix-assisted laser desorption ionization, time-of-flight MS, MALD...


US Patent US10889546 (2021)

More data for this
Ligand-Target Pair
Prolyl hydroxylase EGLN3


(Homo sapiens (Human))
BDBM477219
PNG
(US10889546, Example 28)
Show SMILES NC(=O)CNC(=O)c1ncc(cc1O)C#CCOc1ccc(Cl)cc1
Show InChI InChI=1S/C17H14ClN3O4/c18-12-3-5-13(6-4-12)25-7-1-2-11-8-14(22)16(20-9-11)17(24)21-10-15(19)23/h3-6,8-9,22H,7,10H2,(H2,19,23)(H,21,24)
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n/an/a 99.2n/an/an/an/an/an/a



Jiangsu Hengrui Medicine Co., Ltd.

US Patent


Assay Description
The EGLN-1 (or EGLN-3) enzyme activity is determined using mass spectrometry (matrix-assisted laser desorption ionization, time-of-flight MS, MALD...


US Patent US10889546 (2021)

More data for this
Ligand-Target Pair
Prolyl hydroxylase EGLN3


(Homo sapiens (Human))
BDBM477232
PNG
(US10889546, Example 41)
Show SMILES OC(=O)CNC(=O)c1ncc(cc1O)C#CCOc1cccc(OC2CC2)c1
Show InChI InChI=1S/C20H18N2O6/c23-17-9-13(11-21-19(17)20(26)22-12-18(24)25)3-2-8-27-15-4-1-5-16(10-15)28-14-6-7-14/h1,4-5,9-11,14,23H,6-8,12H2,(H,22,26)(H,24,25)
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n/an/a 101n/an/an/an/an/an/a



Jiangsu Hengrui Medicine Co., Ltd.

US Patent


Assay Description
The EGLN-1 (or EGLN-3) enzyme activity is determined using mass spectrometry (matrix-assisted laser desorption ionization, time-of-flight MS, MALD...


US Patent US10889546 (2021)

More data for this
Ligand-Target Pair
Egl nine homolog 1


(Homo sapiens (Human))
BDBM477238
PNG
(US10889546, Example 46)
Show SMILES OC(=O)CNC(=O)c1ncc(cc1O)C#CCOc1cccc(Cl)c1
Show InChI InChI=1S/C17H13ClN2O5/c18-12-4-1-5-13(8-12)25-6-2-3-11-7-14(21)16(19-9-11)17(24)20-10-15(22)23/h1,4-5,7-9,21H,6,10H2,(H,20,24)(H,22,23)
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n/an/a 102n/an/an/an/an/an/a



Jiangsu Hengrui Medicine Co., Ltd.

US Patent


Assay Description
The EGLN-1 (or EGLN-3) enzyme activity is determined using mass spectrometry (matrix-assisted laser desorption ionization, time-of-flight MS, MALD...


US Patent US10889546 (2021)

More data for this
Ligand-Target Pair
Egl nine homolog 1


(Homo sapiens (Human))
BDBM477225
PNG
(US10889546, Example 34)
Show SMILES Cc1ccc(OCC#Cc2cnc(C(=O)NCC(O)=O)c(O)c2)cc1
Show InChI InChI=1S/C18H16N2O5/c1-12-4-6-14(7-5-12)25-8-2-3-13-9-15(21)17(19-10-13)18(24)20-11-16(22)23/h4-7,9-10,21H,8,11H2,1H3,(H,20,24)(H,22,23)
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n/an/a 110n/an/an/an/an/an/a



Jiangsu Hengrui Medicine Co., Ltd.

US Patent


Assay Description
The EGLN-1 (or EGLN-3) enzyme activity is determined using mass spectrometry (matrix-assisted laser desorption ionization, time-of-flight MS, MALD...


US Patent US10889546 (2021)

More data for this
Ligand-Target Pair
Egl nine homolog 1


(Homo sapiens (Human))
BDBM477219
PNG
(US10889546, Example 28)
Show SMILES NC(=O)CNC(=O)c1ncc(cc1O)C#CCOc1ccc(Cl)cc1
Show InChI InChI=1S/C17H14ClN3O4/c18-12-3-5-13(6-4-12)25-7-1-2-11-8-14(22)16(20-9-11)17(24)21-10-15(19)23/h3-6,8-9,22H,7,10H2,(H2,19,23)(H,21,24)
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n/an/a 125n/an/an/an/an/an/a



Jiangsu Hengrui Medicine Co., Ltd.

US Patent


Assay Description
The EGLN-1 (or EGLN-3) enzyme activity is determined using mass spectrometry (matrix-assisted laser desorption ionization, time-of-flight MS, MALD...


US Patent US10889546 (2021)

More data for this
Ligand-Target Pair
Egl nine homolog 1


(Homo sapiens (Human))
BDBM477224
PNG
(US10889546, Example 33)
Show SMILES OC(=O)CNC(=O)c1ncc(cc1O)C#CCOc1ccccc1
Show InChI InChI=1S/C17H14N2O5/c20-14-9-12(5-4-8-24-13-6-2-1-3-7-13)10-18-16(14)17(23)19-11-15(21)22/h1-3,6-7,9-10,20H,8,11H2,(H,19,23)(H,21,22)
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n/an/a 170n/an/an/an/an/an/a



Jiangsu Hengrui Medicine Co., Ltd.

US Patent


Assay Description
The EGLN-1 (or EGLN-3) enzyme activity is determined using mass spectrometry (matrix-assisted laser desorption ionization, time-of-flight MS, MALD...


US Patent US10889546 (2021)

More data for this
Ligand-Target Pair
Egl nine homolog 1


(Homo sapiens (Human))
BDBM477237
PNG
(US10889546, Example 45)
Show SMILES OC(=O)CNC(=O)c1ncc(cc1O)C#CCOc1ccccc1Cl
Show InChI InChI=1S/C17H13ClN2O5/c18-12-5-1-2-6-14(12)25-7-3-4-11-8-13(21)16(19-9-11)17(24)20-10-15(22)23/h1-2,5-6,8-9,21H,7,10H2,(H,20,24)(H,22,23)
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n/an/a 175n/an/an/an/an/an/a



Jiangsu Hengrui Medicine Co., Ltd.

US Patent


Assay Description
The EGLN-1 (or EGLN-3) enzyme activity is determined using mass spectrometry (matrix-assisted laser desorption ionization, time-of-flight MS, MALD...


US Patent US10889546 (2021)

More data for this
Ligand-Target Pair
Egl nine homolog 1


(Homo sapiens (Human))
BDBM477240
PNG
(US10889546, Example 48)
Show SMILES OC(=O)CNC(=O)c1ncc(cc1O)C#CCOc1cccc(Br)c1
Show InChI InChI=1S/C17H13BrN2O5/c18-12-4-1-5-13(8-12)25-6-2-3-11-7-14(21)16(19-9-11)17(24)20-10-15(22)23/h1,4-5,7-9,21H,6,10H2,(H,20,24)(H,22,23)
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n/an/a 178n/an/an/an/an/an/a



Jiangsu Hengrui Medicine Co., Ltd.

US Patent


Assay Description
The EGLN-1 (or EGLN-3) enzyme activity is determined using mass spectrometry (matrix-assisted laser desorption ionization, time-of-flight MS, MALD...


US Patent US10889546 (2021)

More data for this
Ligand-Target Pair
Egl nine homolog 1


(Homo sapiens (Human))
BDBM477230
PNG
(US10889546, Example 39)
Show SMILES OCc1ccc(OCC#Cc2cnc(C(=O)NCC(O)=O)c(O)c2)cc1
Show InChI InChI=1S/C18H16N2O6/c21-11-12-3-5-14(6-4-12)26-7-1-2-13-8-15(22)17(19-9-13)18(25)20-10-16(23)24/h3-6,8-9,21-22H,7,10-11H2,(H,20,25)(H,23,24)
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n/an/a 186n/an/an/an/an/an/a



Jiangsu Hengrui Medicine Co., Ltd.

US Patent


Assay Description
The EGLN-1 (or EGLN-3) enzyme activity is determined using mass spectrometry (matrix-assisted laser desorption ionization, time-of-flight MS, MALD...


US Patent US10889546 (2021)

More data for this
Ligand-Target Pair
Egl nine homolog 1


(Homo sapiens (Human))
BDBM477239
PNG
(US10889546, Example 47)
Show SMILES OC(=O)CNC(=O)c1ncc(cc1O)C#CCOc1ccc(F)cc1
Show InChI InChI=1S/C17H13FN2O5/c18-12-3-5-13(6-4-12)25-7-1-2-11-8-14(21)16(19-9-11)17(24)20-10-15(22)23/h3-6,8-9,21H,7,10H2,(H,20,24)(H,22,23)
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n/an/a 187n/an/an/an/an/an/a



Jiangsu Hengrui Medicine Co., Ltd.

US Patent


Assay Description
The EGLN-1 (or EGLN-3) enzyme activity is determined using mass spectrometry (matrix-assisted laser desorption ionization, time-of-flight MS, MALD...


US Patent US10889546 (2021)

More data for this
Ligand-Target Pair
Prolyl hydroxylase EGLN3


(Homo sapiens (Human))
BDBM477198
PNG
(US10889546, Example 8)
Show SMILES OCc1ccc(cc1)C#Cc1cc(O)c(nc1Cl)C(=O)NCC(O)=O
Show InChI InChI=1S/C17H13ClN2O5/c18-16-12(6-5-10-1-3-11(9-21)4-2-10)7-13(22)15(20-16)17(25)19-8-14(23)24/h1-4,7,21-22H,8-9H2,(H,19,25)(H,23,24)
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n/an/a 210n/an/an/an/an/an/a



Jiangsu Hengrui Medicine Co., Ltd.

US Patent


Assay Description
The EGLN-1 (or EGLN-3) enzyme activity is determined using mass spectrometry (matrix-assisted laser desorption ionization, time-of-flight MS, MALD...


US Patent US10889546 (2021)

More data for this
Ligand-Target Pair
Egl nine homolog 1


(Homo sapiens (Human))
BDBM477246
PNG
(US10889546, Example 54)
Show SMILES OC(=O)CNC(=O)c1ncc(cc1O)C#CCOc1ccc(cc1)C(=O)N1CCCC1
Show InChI InChI=1S/C22H21N3O6/c26-18-12-15(13-23-20(18)21(29)24-14-19(27)28)4-3-11-31-17-7-5-16(6-8-17)22(30)25-9-1-2-10-25/h5-8,12-13,26H,1-2,9-11,14H2,(H,24,29)(H,27,28)
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n/an/a 211n/an/an/an/an/an/a



Jiangsu Hengrui Medicine Co., Ltd.

US Patent


Assay Description
The EGLN-1 (or EGLN-3) enzyme activity is determined using mass spectrometry (matrix-assisted laser desorption ionization, time-of-flight MS, MALD...


US Patent US10889546 (2021)

More data for this
Ligand-Target Pair
Egl nine homolog 1


(Homo sapiens (Human))
BDBM477197
PNG
(US10889546, Example 7)
Show SMILES Cc1ccc(cc1)C#Cc1cc(O)c(nc1C)C(=O)NCC(O)=O
Show InChI InChI=1S/C18H16N2O4/c1-11-3-5-13(6-4-11)7-8-14-9-15(21)17(20-12(14)2)18(24)19-10-16(22)23/h3-6,9,21H,10H2,1-2H3,(H,19,24)(H,22,23)
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n/an/a 215n/an/an/an/an/an/a



Jiangsu Hengrui Medicine Co., Ltd.

US Patent


Assay Description
The EGLN-1 (or EGLN-3) enzyme activity is determined using mass spectrometry (matrix-assisted laser desorption ionization, time-of-flight MS, MALD...


US Patent US10889546 (2021)

More data for this
Ligand-Target Pair
Egl nine homolog 1


(Homo sapiens (Human))
BDBM477247
PNG
(US10889546, Example 55)
Show SMILES OC(=O)CNC(=O)c1nc(Cl)c(cc1O)C#CCOc1ccc(cc1)C(=O)N1CC1
Show InChI InChI=1S/C20H16ClN3O6/c21-18-13(10-15(25)17(23-18)19(28)22-11-16(26)27)2-1-9-30-14-5-3-12(4-6-14)20(29)24-7-8-24/h3-6,10,25H,7-9,11H2,(H,22,28)(H,26,27)
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n/an/a 221n/an/an/an/an/an/a



Jiangsu Hengrui Medicine Co., Ltd.

US Patent


Assay Description
The EGLN-1 (or EGLN-3) enzyme activity is determined using mass spectrometry (matrix-assisted laser desorption ionization, time-of-flight MS, MALD...


US Patent US10889546 (2021)

More data for this
Ligand-Target Pair
Prolyl hydroxylase EGLN3


(Homo sapiens (Human))
BDBM477231
PNG
(US10889546, Example 40)
Show SMILES CC(C)(C)Oc1cccc(OCC#Cc2cnc(C(=O)NCC(O)=O)c(O)c2)c1
Show InChI InChI=1S/C21H22N2O6/c1-21(2,3)29-16-8-4-7-15(11-16)28-9-5-6-14-10-17(24)19(22-12-14)20(27)23-13-18(25)26/h4,7-8,10-12,24H,9,13H2,1-3H3,(H,23,27)(H,25,26)
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n/an/a 221n/an/an/an/an/an/a



Jiangsu Hengrui Medicine Co., Ltd.

US Patent


Assay Description
The EGLN-1 (or EGLN-3) enzyme activity is determined using mass spectrometry (matrix-assisted laser desorption ionization, time-of-flight MS, MALD...


US Patent US10889546 (2021)

More data for this
Ligand-Target Pair
Egl nine homolog 1


(Homo sapiens (Human))
BDBM477211
PNG
(US10889546, Example 20)
Show SMILES OC(=O)CNC(=O)c1ncc(cc1O)C#Cc1ccccc1C#N
Show InChI InChI=1S/C17H11N3O4/c18-8-13-4-2-1-3-12(13)6-5-11-7-14(21)16(19-9-11)17(24)20-10-15(22)23/h1-4,7,9,21H,10H2,(H,20,24)(H,22,23)
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n/an/a 234n/an/an/an/an/an/a



Jiangsu Hengrui Medicine Co., Ltd.

US Patent


Assay Description
The EGLN-1 (or EGLN-3) enzyme activity is determined using mass spectrometry (matrix-assisted laser desorption ionization, time-of-flight MS, MALD...


US Patent US10889546 (2021)

More data for this
Ligand-Target Pair
Egl nine homolog 1


(Homo sapiens (Human))
BDBM477257
PNG
(US10889546, Example 65)
Show SMILES OC(=O)CNC(=O)c1ncc(cc1O)C#CCNc1ccc(Cl)cc1
Show InChI InChI=1S/C17H14ClN3O4/c18-12-3-5-13(6-4-12)19-7-1-2-11-8-14(22)16(20-9-11)17(25)21-10-15(23)24/h3-6,8-9,19,22H,7,10H2,(H,21,25)(H,23,24)
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n/an/a 290n/an/an/an/an/an/a



Jiangsu Hengrui Medicine Co., Ltd.

US Patent


Assay Description
The EGLN-1 (or EGLN-3) enzyme activity is determined using mass spectrometry (matrix-assisted laser desorption ionization, time-of-flight MS, MALD...


US Patent US10889546 (2021)

More data for this
Ligand-Target Pair
Egl nine homolog 1


(Homo sapiens (Human))
BDBM477205
PNG
(US10889546, Example 14)
Show SMILES Cc1cccc(c1)C#Cc1cnc(C(=O)NCC(O)=O)c(O)c1
Show InChI InChI=1S/C17H14N2O4/c1-11-3-2-4-12(7-11)5-6-13-8-14(20)16(18-9-13)17(23)19-10-15(21)22/h2-4,7-9,20H,10H2,1H3,(H,19,23)(H,21,22)
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n/an/a 298n/an/an/an/an/an/a



Jiangsu Hengrui Medicine Co., Ltd.

US Patent


Assay Description
The EGLN-1 (or EGLN-3) enzyme activity is determined using mass spectrometry (matrix-assisted laser desorption ionization, time-of-flight MS, MALD...


US Patent US10889546 (2021)

More data for this
Ligand-Target Pair
Egl nine homolog 1


(Homo sapiens (Human))
BDBM477244
PNG
(US10889546, Example 52)
Show SMILES NC(=O)c1ccc(OCC#Cc2cnc(C(=O)NCC(O)=O)c(O)c2)cc1
Show InChI InChI=1S/C18H15N3O6/c19-17(25)12-3-5-13(6-4-12)27-7-1-2-11-8-14(22)16(20-9-11)18(26)21-10-15(23)24/h3-6,8-9,22H,7,10H2,(H2,19,25)(H,21,26)(H,23,24)
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n/an/a 310n/an/an/an/an/an/a



Jiangsu Hengrui Medicine Co., Ltd.

US Patent


Assay Description
The EGLN-1 (or EGLN-3) enzyme activity is determined using mass spectrometry (matrix-assisted laser desorption ionization, time-of-flight MS, MALD...


US Patent US10889546 (2021)

More data for this
Ligand-Target Pair
Egl nine homolog 1


(Homo sapiens (Human))
BDBM477210
PNG
(US10889546, Example 19)
Show SMILES OC(=O)CNC(=O)c1ncc(cc1O)C#Cc1ccc(cc1)C#N
Show InChI InChI=1S/C17H11N3O4/c18-8-12-4-1-11(2-5-12)3-6-13-7-14(21)16(19-9-13)17(24)20-10-15(22)23/h1-2,4-5,7,9,21H,10H2,(H,20,24)(H,22,23)
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Jiangsu Hengrui Medicine Co., Ltd.

US Patent


Assay Description
The EGLN-1 (or EGLN-3) enzyme activity is determined using mass spectrometry (matrix-assisted laser desorption ionization, time-of-flight MS, MALD...


US Patent US10889546 (2021)

More data for this
Ligand-Target Pair
Egl nine homolog 1


(Homo sapiens (Human))
BDBM477242
PNG
(US10889546, Example 50)
Show SMILES CC(=O)Nc1ccc(OCC#Cc2cnc(C(=O)NCC(O)=O)c(O)c2)cc1
Show InChI InChI=1S/C19H17N3O6/c1-12(23)22-14-4-6-15(7-5-14)28-8-2-3-13-9-16(24)18(20-10-13)19(27)21-11-17(25)26/h4-7,9-10,24H,8,11H2,1H3,(H,21,27)(H,22,23)(H,25,26)
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n/an/a 311n/an/an/an/an/an/a



Jiangsu Hengrui Medicine Co., Ltd.

US Patent


Assay Description
The EGLN-1 (or EGLN-3) enzyme activity is determined using mass spectrometry (matrix-assisted laser desorption ionization, time-of-flight MS, MALD...


US Patent US10889546 (2021)

More data for this
Ligand-Target Pair
Egl nine homolog 1


(Homo sapiens (Human))
BDBM477256
PNG
(US10889546, Example 64)
Show SMILES OC(=O)CNC(=O)c1ncc(cc1O)C#CCNc1ccccc1
Show InChI InChI=1S/C17H15N3O4/c21-14-9-12(5-4-8-18-13-6-2-1-3-7-13)10-19-16(14)17(24)20-11-15(22)23/h1-3,6-7,9-10,18,21H,8,11H2,(H,20,24)(H,22,23)
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n/an/a 326n/an/an/an/an/an/a



Jiangsu Hengrui Medicine Co., Ltd.

US Patent


Assay Description
The EGLN-1 (or EGLN-3) enzyme activity is determined using mass spectrometry (matrix-assisted laser desorption ionization, time-of-flight MS, MALD...


US Patent US10889546 (2021)

More data for this
Ligand-Target Pair
Egl nine homolog 1


(Homo sapiens (Human))
BDBM477227
PNG
(US10889546, Example 36)
Show SMILES CCc1ccc(OCC#Cc2cnc(C(=O)NCC(O)=O)c(O)c2)cc1
Show InChI InChI=1S/C19H18N2O5/c1-2-13-5-7-15(8-6-13)26-9-3-4-14-10-16(22)18(20-11-14)19(25)21-12-17(23)24/h5-8,10-11,22H,2,9,12H2,1H3,(H,21,25)(H,23,24)
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n/an/a 378n/an/an/an/an/an/a



Jiangsu Hengrui Medicine Co., Ltd.

US Patent


Assay Description
The EGLN-1 (or EGLN-3) enzyme activity is determined using mass spectrometry (matrix-assisted laser desorption ionization, time-of-flight MS, MALD...


US Patent US10889546 (2021)

More data for this
Ligand-Target Pair
Egl nine homolog 1


(Homo sapiens (Human))
BDBM477228
PNG
(US10889546, Example 37)
Show SMILES CC(C)(C)c1ccc(OCC#Cc2cnc(C(=O)NCC(O)=O)c(O)c2)cc1
Show InChI InChI=1S/C21H22N2O5/c1-21(2,3)15-6-8-16(9-7-15)28-10-4-5-14-11-17(24)19(22-12-14)20(27)23-13-18(25)26/h6-9,11-12,24H,10,13H2,1-3H3,(H,23,27)(H,25,26)
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Jiangsu Hengrui Medicine Co., Ltd.

US Patent


Assay Description
The EGLN-1 (or EGLN-3) enzyme activity is determined using mass spectrometry (matrix-assisted laser desorption ionization, time-of-flight MS, MALD...


US Patent US10889546 (2021)

More data for this
Ligand-Target Pair
Egl nine homolog 1


(Homo sapiens (Human))
BDBM477252
PNG
(US10889546, Example 60)
Show SMILES OC(=O)CNC(=O)c1ncc(cc1O)C#CCOc1cccc2ccoc12
Show InChI InChI=1S/C19H14N2O6/c22-14-9-12(10-20-17(14)19(25)21-11-16(23)24)3-2-7-26-15-5-1-4-13-6-8-27-18(13)15/h1,4-6,8-10,22H,7,11H2,(H,21,25)(H,23,24)
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n/an/a 399n/an/an/an/an/an/a



Jiangsu Hengrui Medicine Co., Ltd.

US Patent


Assay Description
The EGLN-1 (or EGLN-3) enzyme activity is determined using mass spectrometry (matrix-assisted laser desorption ionization, time-of-flight MS, MALD...


US Patent US10889546 (2021)

More data for this
Ligand-Target Pair
Egl nine homolog 1


(Homo sapiens (Human))
BDBM477258
PNG
(US10889546, Example 66)
Show SMILES CCc1ccc(NCC#Cc2cnc(C(=O)NCC(O)=O)c(O)c2)cc1
Show InChI InChI=1S/C19H19N3O4/c1-2-13-5-7-15(8-6-13)20-9-3-4-14-10-16(23)18(21-11-14)19(26)22-12-17(24)25/h5-8,10-11,20,23H,2,9,12H2,1H3,(H,22,26)(H,24,25)
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n/an/a 400n/an/an/an/an/an/a



Jiangsu Hengrui Medicine Co., Ltd.

US Patent


Assay Description
The EGLN-1 (or EGLN-3) enzyme activity is determined using mass spectrometry (matrix-assisted laser desorption ionization, time-of-flight MS, MALD...


US Patent US10889546 (2021)

More data for this
Ligand-Target Pair
Egl nine homolog 1


(Homo sapiens (Human))
BDBM477234
PNG
(US10889546, Example 43)
Show SMILES OC(=O)CNC(=O)c1ncc(cc1O)C#CCOc1ccc(CF)o1
Show InChI InChI=1S/C16H14FN2O6/c1-17-12-4-5-14(25-12)24-6-2-3-10-7-11(20)15(18-8-10)16(23)19-9-13(21)22/h4-5,7-8,20H,6,9H2,1H3,(H,19,23)(H,21,22)
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n/an/a 402n/an/an/an/an/an/a



Jiangsu Hengrui Medicine Co., Ltd.

US Patent


Assay Description
The EGLN-1 (or EGLN-3) enzyme activity is determined using mass spectrometry (matrix-assisted laser desorption ionization, time-of-flight MS, MALD...


US Patent US10889546 (2021)

More data for this
Ligand-Target Pair
Egl nine homolog 1


(Homo sapiens (Human))
BDBM477251
PNG
(US10889546, Example 59)
Show SMILES OC(=O)CNC(=O)c1ncc(cc1O)C#CCOc1cccc2ncccc12
Show InChI InChI=1S/C20H15N3O5/c24-16-10-13(11-22-19(16)20(27)23-12-18(25)26)4-3-9-28-17-7-1-6-15-14(17)5-2-8-21-15/h1-2,5-8,10-11,24H,9,12H2,(H,23,27)(H,25,26)
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Jiangsu Hengrui Medicine Co., Ltd.

US Patent


Assay Description
The EGLN-1 (or EGLN-3) enzyme activity is determined using mass spectrometry (matrix-assisted laser desorption ionization, time-of-flight MS, MALD...


US Patent US10889546 (2021)

More data for this
Ligand-Target Pair
Egl nine homolog 1


(Homo sapiens (Human))
BDBM477243
PNG
(US10889546, Example 51)
Show SMILES CC(C)(C)NC(=O)c1ccc(OCC#Cc2cnc(C(=O)NCC(O)=O)c(O)c2)cc1
Show InChI InChI=1S/C22H23N3O6/c1-22(2,3)25-20(29)15-6-8-16(9-7-15)31-10-4-5-14-11-17(26)19(23-12-14)21(30)24-13-18(27)28/h6-9,11-12,26H,10,13H2,1-3H3,(H,24,30)(H,25,29)(H,27,28)
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n/an/a 442n/an/an/an/an/an/a



Jiangsu Hengrui Medicine Co., Ltd.

US Patent


Assay Description
The EGLN-1 (or EGLN-3) enzyme activity is determined using mass spectrometry (matrix-assisted laser desorption ionization, time-of-flight MS, MALD...


US Patent US10889546 (2021)

More data for this
Ligand-Target Pair
Egl nine homolog 1


(Homo sapiens (Human))
BDBM477254
PNG
(US10889546, Example 62)
Show SMILES OC(=O)CNC(=O)c1ncc(cc1O)C#CCOc1cc(Cl)cc(Cl)c1
Show InChI InChI=1S/C17H12Cl2N2O5/c18-11-5-12(19)7-13(6-11)26-3-1-2-10-4-14(22)16(20-8-10)17(25)21-9-15(23)24/h4-8,22H,3,9H2,(H,21,25)(H,23,24)
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n/an/a 450n/an/an/an/an/an/a



Jiangsu Hengrui Medicine Co., Ltd.

US Patent


Assay Description
The EGLN-1 (or EGLN-3) enzyme activity is determined using mass spectrometry (matrix-assisted laser desorption ionization, time-of-flight MS, MALD...


US Patent US10889546 (2021)

More data for this
Ligand-Target Pair
Egl nine homolog 1


(Homo sapiens (Human))
BDBM477208
PNG
(US10889546, Example 17)
Show SMILES COc1cccc(c1)C#Cc1cnc(C(=O)NCC(O)=O)c(O)c1
Show InChI InChI=1S/C17H14N2O5/c1-24-13-4-2-3-11(7-13)5-6-12-8-14(20)16(18-9-12)17(23)19-10-15(21)22/h2-4,7-9,20H,10H2,1H3,(H,19,23)(H,21,22)
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n/an/a 464n/an/an/an/an/an/a



Jiangsu Hengrui Medicine Co., Ltd.

US Patent


Assay Description
The EGLN-1 (or EGLN-3) enzyme activity is determined using mass spectrometry (matrix-assisted laser desorption ionization, time-of-flight MS, MALD...


US Patent US10889546 (2021)

More data for this
Ligand-Target Pair
Egl nine homolog 1


(Homo sapiens (Human))
BDBM477232
PNG
(US10889546, Example 41)
Show SMILES OC(=O)CNC(=O)c1ncc(cc1O)C#CCOc1cccc(OC2CC2)c1
Show InChI InChI=1S/C20H18N2O6/c23-17-9-13(11-21-19(17)20(26)22-12-18(24)25)3-2-8-27-15-4-1-5-16(10-15)28-14-6-7-14/h1,4-5,9-11,14,23H,6-8,12H2,(H,22,26)(H,24,25)
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n/an/a 489n/an/an/an/an/an/a



Jiangsu Hengrui Medicine Co., Ltd.

US Patent


Assay Description
The EGLN-1 (or EGLN-3) enzyme activity is determined using mass spectrometry (matrix-assisted laser desorption ionization, time-of-flight MS, MALD...


US Patent US10889546 (2021)

More data for this
Ligand-Target Pair
Egl nine homolog 1


(Homo sapiens (Human))
BDBM477212
PNG
(US10889546, Example 21)
Show SMILES OC(=O)CNC(=O)c1ncc(cc1O)C#Cc1ccc(cc1)C(F)(F)F
Show InChI InChI=1S/C17H11F3N2O4/c18-17(19,20)12-5-3-10(4-6-12)1-2-11-7-13(23)15(21-8-11)16(26)22-9-14(24)25/h3-8,23H,9H2,(H,22,26)(H,24,25)
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n/an/a 510n/an/an/an/an/an/a



Jiangsu Hengrui Medicine Co., Ltd.

US Patent


Assay Description
The EGLN-1 (or EGLN-3) enzyme activity is determined using mass spectrometry (matrix-assisted laser desorption ionization, time-of-flight MS, MALD...


US Patent US10889546 (2021)

More data for this
Ligand-Target Pair
Egl nine homolog 1


(Homo sapiens (Human))
BDBM477233
PNG
(US10889546, Example 42)
Show SMILES OC(=O)CNC(=O)c1ncc(cc1O)C#CCOc1ccc(cc1)C(F)(F)F
Show InChI InChI=1S/C18H13F3N2O5/c19-18(20,21)12-3-5-13(6-4-12)28-7-1-2-11-8-14(24)16(22-9-11)17(27)23-10-15(25)26/h3-6,8-9,24H,7,10H2,(H,23,27)(H,25,26)
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n/an/a 515n/an/an/an/an/an/a



Jiangsu Hengrui Medicine Co., Ltd.

US Patent


Assay Description
The EGLN-1 (or EGLN-3) enzyme activity is determined using mass spectrometry (matrix-assisted laser desorption ionization, time-of-flight MS, MALD...


US Patent US10889546 (2021)

More data for this
Ligand-Target Pair
Egl nine homolog 1


(Homo sapiens (Human))
BDBM477245
PNG
(US10889546, Example 53)
Show SMILES CN(C(=O)c1ccc(OCC#Cc2cnc(C(=O)NCC(O)=O)c(O)c2)cn1)C(C)(C)C
Show InChI InChI=1S/C22H24N4O6/c1-22(2,3)26(4)21(31)16-8-7-15(12-23-16)32-9-5-6-14-10-17(27)19(24-11-14)20(30)25-13-18(28)29/h7-8,10-12,27H,9,13H2,1-4H3,(H,25,30)(H,28,29)
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n/an/a 520n/an/an/an/an/an/a



Jiangsu Hengrui Medicine Co., Ltd.

US Patent


Assay Description
The EGLN-1 (or EGLN-3) enzyme activity is determined using mass spectrometry (matrix-assisted laser desorption ionization, time-of-flight MS, MALD...


US Patent US10889546 (2021)

More data for this
Ligand-Target Pair
Egl nine homolog 1


(Homo sapiens (Human))
BDBM477253
PNG
(US10889546, Example 61)
Show SMILES OC(=O)CNC(=O)c1ncc(cc1O)C#CCOc1cccc(Cl)c1Cl
Show InChI InChI=1S/C17H12Cl2N2O5/c18-11-4-1-5-13(15(11)19)26-6-2-3-10-7-12(22)16(20-8-10)17(25)21-9-14(23)24/h1,4-5,7-8,22H,6,9H2,(H,21,25)(H,23,24)
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n/an/a 527n/an/an/an/an/an/a



Jiangsu Hengrui Medicine Co., Ltd.

US Patent


Assay Description
The EGLN-1 (or EGLN-3) enzyme activity is determined using mass spectrometry (matrix-assisted laser desorption ionization, time-of-flight MS, MALD...


US Patent US10889546 (2021)

More data for this
Ligand-Target Pair
Egl nine homolog 1


(Homo sapiens (Human))
BDBM477249
PNG
(US10889546, Example 57)
Show SMILES OC(=O)CNC(=O)c1ncc(cc1O)C#CCOc1ccc(cc1)-c1ccccc1
Show InChI InChI=1S/C23H18N2O5/c26-20-13-16(14-24-22(20)23(29)25-15-21(27)28)5-4-12-30-19-10-8-18(9-11-19)17-6-2-1-3-7-17/h1-3,6-11,13-14,26H,12,15H2,(H,25,29)(H,27,28)
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Jiangsu Hengrui Medicine Co., Ltd.

US Patent


Assay Description
The EGLN-1 (or EGLN-3) enzyme activity is determined using mass spectrometry (matrix-assisted laser desorption ionization, time-of-flight MS, MALD...


US Patent US10889546 (2021)

More data for this
Ligand-Target Pair
Egl nine homolog 1


(Homo sapiens (Human))
BDBM477231
PNG
(US10889546, Example 40)
Show SMILES CC(C)(C)Oc1cccc(OCC#Cc2cnc(C(=O)NCC(O)=O)c(O)c2)c1
Show InChI InChI=1S/C21H22N2O6/c1-21(2,3)29-16-8-4-7-15(11-16)28-9-5-6-14-10-17(24)19(22-12-14)20(27)23-13-18(25)26/h4,7-8,10-12,24H,9,13H2,1-3H3,(H,23,27)(H,25,26)
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n/an/a 544n/an/an/an/an/an/a



Jiangsu Hengrui Medicine Co., Ltd.

US Patent


Assay Description
The EGLN-1 (or EGLN-3) enzyme activity is determined using mass spectrometry (matrix-assisted laser desorption ionization, time-of-flight MS, MALD...


US Patent US10889546 (2021)

More data for this
Ligand-Target Pair
Egl nine homolog 1


(Homo sapiens (Human))
BDBM477198
PNG
(US10889546, Example 8)
Show SMILES OCc1ccc(cc1)C#Cc1cc(O)c(nc1Cl)C(=O)NCC(O)=O
Show InChI InChI=1S/C17H13ClN2O5/c18-16-12(6-5-10-1-3-11(9-21)4-2-10)7-13(22)15(20-16)17(25)19-8-14(23)24/h1-4,7,21-22H,8-9H2,(H,19,25)(H,23,24)
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Jiangsu Hengrui Medicine Co., Ltd.

US Patent


Assay Description
The EGLN-1 (or EGLN-3) enzyme activity is determined using mass spectrometry (matrix-assisted laser desorption ionization, time-of-flight MS, MALD...


US Patent US10889546 (2021)

More data for this
Ligand-Target Pair
Egl nine homolog 1


(Homo sapiens (Human))
BDBM477207
PNG
(US10889546, Example 16)
Show SMILES OCc1ccc(cc1)C#Cc1cnc(C(=O)NCC(O)=O)c(O)c1
Show InChI InChI=1S/C17H14N2O5/c20-10-12-4-1-11(2-5-12)3-6-13-7-14(21)16(18-8-13)17(24)19-9-15(22)23/h1-2,4-5,7-8,20-21H,9-10H2,(H,19,24)(H,22,23)
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n/an/a 564n/an/an/an/an/an/a



Jiangsu Hengrui Medicine Co., Ltd.

US Patent


Assay Description
The EGLN-1 (or EGLN-3) enzyme activity is determined using mass spectrometry (matrix-assisted laser desorption ionization, time-of-flight MS, MALD...


US Patent US10889546 (2021)

More data for this
Ligand-Target Pair
Egl nine homolog 1


(Homo sapiens (Human))
BDBM477206
PNG
(US10889546, Example 15)
Show SMILES OC(=O)CNC(=O)c1ncc(cc1O)C#Cc1ccc(F)cc1
Show InChI InChI=1S/C16H11FN2O4/c17-12-5-3-10(4-6-12)1-2-11-7-13(20)15(18-8-11)16(23)19-9-14(21)22/h3-8,20H,9H2,(H,19,23)(H,21,22)
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n/an/a 567n/an/an/an/an/an/a



Jiangsu Hengrui Medicine Co., Ltd.

US Patent


Assay Description
The EGLN-1 (or EGLN-3) enzyme activity is determined using mass spectrometry (matrix-assisted laser desorption ionization, time-of-flight MS, MALD...


US Patent US10889546 (2021)

More data for this
Ligand-Target Pair
Egl nine homolog 1


(Homo sapiens (Human))
BDBM50431015
PNG
(CHEMBL2338329 | US10889546, FG-4592 | US9115085, C...)
Show SMILES Cc1nc(C(=O)NCC(O)=O)c(O)c2ccc(Oc3ccccc3)cc12
Show InChI InChI=1S/C19H16N2O5/c1-11-15-9-13(26-12-5-3-2-4-6-12)7-8-14(15)18(24)17(21-11)19(25)20-10-16(22)23/h2-9,24H,10H2,1H3,(H,20,25)(H,22,23)
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n/an/a 599n/an/an/an/an/an/a



Jiangsu Hengrui Medicine Co., Ltd.

US Patent


Assay Description
The EGLN-1 (or EGLN-3) enzyme activity is determined using mass spectrometry (matrix-assisted laser desorption ionization, time-of-flight MS, MALD...


US Patent US10889546 (2021)

More data for this
Ligand-Target Pair
Egl nine homolog 1


(Homo sapiens (Human))
BDBM477250
PNG
(US10889546, Example 58)
Show SMILES OC(=O)CNC(=O)c1ncc(cc1O)C#CCOc1ccc2ccccc2c1
Show InChI InChI=1S/C21H16N2O5/c24-18-10-14(12-22-20(18)21(27)23-13-19(25)26)4-3-9-28-17-8-7-15-5-1-2-6-16(15)11-17/h1-2,5-8,10-12,24H,9,13H2,(H,23,27)(H,25,26)
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n/an/a 606n/an/an/an/an/an/a



Jiangsu Hengrui Medicine Co., Ltd.

US Patent


Assay Description
The EGLN-1 (or EGLN-3) enzyme activity is determined using mass spectrometry (matrix-assisted laser desorption ionization, time-of-flight MS, MALD...


US Patent US10889546 (2021)

More data for this
Ligand-Target Pair
Prolyl hydroxylase EGLN3


(Homo sapiens (Human))
BDBM477201
PNG
(US10889546, Example 11)
Show SMILES CC(C)(NC(=O)c1ncc(cc1O)C#Cc1ccc(F)cc1)C(O)=O
Show InChI InChI=1S/C18H15FN2O4/c1-18(2,17(24)25)21-16(23)15-14(22)9-12(10-20-15)4-3-11-5-7-13(19)8-6-11/h5-10,22H,1-2H3,(H,21,23)(H,24,25)
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n/an/a 645n/an/an/an/an/an/a



Jiangsu Hengrui Medicine Co., Ltd.

US Patent


Assay Description
The EGLN-1 (or EGLN-3) enzyme activity is determined using mass spectrometry (matrix-assisted laser desorption ionization, time-of-flight MS, MALD...


US Patent US10889546 (2021)

More data for this
Ligand-Target Pair
Egl nine homolog 1


(Homo sapiens (Human))
BDBM477241
PNG
(US10889546, Example 49)
Show SMILES OC(=O)CNC(=O)c1ncc(cc1O)C#CCOc1cccc(c1)C#N
Show InChI InChI=1S/C18H13N3O5/c19-9-12-3-1-5-14(7-12)26-6-2-4-13-8-15(22)17(20-10-13)18(25)21-11-16(23)24/h1,3,5,7-8,10,22H,6,11H2,(H,21,25)(H,23,24)
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n/an/a 653n/an/an/an/an/an/a



Jiangsu Hengrui Medicine Co., Ltd.

US Patent


Assay Description
The EGLN-1 (or EGLN-3) enzyme activity is determined using mass spectrometry (matrix-assisted laser desorption ionization, time-of-flight MS, MALD...


US Patent US10889546 (2021)

More data for this
Ligand-Target Pair
Prolyl hydroxylase EGLN3


(Homo sapiens (Human))
BDBM477199
PNG
(US10889546, Example 9)
Show SMILES CC(NC(=O)c1ncc(cc1O)C#Cc1ccc(cc1)C1CC1)C(O)=O
Show InChI InChI=1S/C20H18N2O4/c1-12(20(25)26)22-19(24)18-17(23)10-14(11-21-18)3-2-13-4-6-15(7-5-13)16-8-9-16/h4-7,10-12,16,23H,8-9H2,1H3,(H,22,24)(H,25,26)
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n/an/a 675n/an/an/an/an/an/a



Jiangsu Hengrui Medicine Co., Ltd.

US Patent


Assay Description
The EGLN-1 (or EGLN-3) enzyme activity is determined using mass spectrometry (matrix-assisted laser desorption ionization, time-of-flight MS, MALD...


US Patent US10889546 (2021)

More data for this
Ligand-Target Pair
Egl nine homolog 1


(Homo sapiens (Human))
BDBM477259
PNG
(US10889546, Example 67)
Show SMILES CN(CC#Cc1cnc(C(=O)NCC(O)=O)c(O)c1)c1ccc(cc1)-c1cnc[nH]1
Show InChI InChI=1S/C21H19N5O4/c1-26(16-6-4-15(5-7-16)17-11-22-13-25-17)8-2-3-14-9-18(27)20(23-10-14)21(30)24-12-19(28)29/h4-7,9-11,13,27H,8,12H2,1H3,(H,22,25)(H,24,30)(H,28,29)
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n/an/a 675n/an/an/an/an/an/a



Jiangsu Hengrui Medicine Co., Ltd.

US Patent


Assay Description
The EGLN-1 (or EGLN-3) enzyme activity is determined using mass spectrometry (matrix-assisted laser desorption ionization, time-of-flight MS, MALD...


US Patent US10889546 (2021)

More data for this
Ligand-Target Pair
Egl nine homolog 1


(Homo sapiens (Human))
BDBM477248
PNG
(US10889546, Example 56)
Show SMILES CN1CCCN(CC1)C(=O)c1ccc(OCC#Cc2cnc(C(=O)NCC(O)=O)c(O)c2)cc1
Show InChI InChI=1S/C24H26N4O6/c1-27-9-3-10-28(12-11-27)24(33)18-5-7-19(8-6-18)34-13-2-4-17-14-20(29)22(25-15-17)23(32)26-16-21(30)31/h5-8,14-15,29H,3,9-13,16H2,1H3,(H,26,32)(H,30,31)
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n/an/a 690n/an/an/an/an/an/a



Jiangsu Hengrui Medicine Co., Ltd.

US Patent


Assay Description
The EGLN-1 (or EGLN-3) enzyme activity is determined using mass spectrometry (matrix-assisted laser desorption ionization, time-of-flight MS, MALD...


US Patent US10889546 (2021)

More data for this
Ligand-Target Pair
Prolyl hydroxylase EGLN3


(Homo sapiens (Human))
BDBM477197
PNG
(US10889546, Example 7)
Show SMILES Cc1ccc(cc1)C#Cc1cc(O)c(nc1C)C(=O)NCC(O)=O
Show InChI InChI=1S/C18H16N2O4/c1-11-3-5-13(6-4-11)7-8-14-9-15(21)17(20-12(14)2)18(24)19-10-16(22)23/h3-6,9,21H,10H2,1-2H3,(H,19,24)(H,22,23)
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n/an/a 711n/an/an/an/an/an/a



Jiangsu Hengrui Medicine Co., Ltd.

US Patent


Assay Description
The EGLN-1 (or EGLN-3) enzyme activity is determined using mass spectrometry (matrix-assisted laser desorption ionization, time-of-flight MS, MALD...


US Patent US10889546 (2021)

More data for this
Ligand-Target Pair
Egl nine homolog 1


(Homo sapiens (Human))
BDBM477255
PNG
(US10889546, Example 63)
Show SMILES Cc1nc(C(=O)NCC(O)=O)c(O)cc1C#CCOc1ccc(cc1)C1CC1
Show InChI InChI=1S/C21H20N2O5/c1-13-16(11-18(24)20(23-13)21(27)22-12-19(25)26)3-2-10-28-17-8-6-15(7-9-17)14-4-5-14/h6-9,11,14,24H,4-5,10,12H2,1H3,(H,22,27)(H,25,26)
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n/an/a 759n/an/an/an/an/an/a



Jiangsu Hengrui Medicine Co., Ltd.

US Patent


Assay Description
The EGLN-1 (or EGLN-3) enzyme activity is determined using mass spectrometry (matrix-assisted laser desorption ionization, time-of-flight MS, MALD...


US Patent US10889546 (2021)

More data for this
Ligand-Target Pair
Prolyl hydroxylase EGLN3


(Homo sapiens (Human))
BDBM477251
PNG
(US10889546, Example 59)
Show SMILES OC(=O)CNC(=O)c1ncc(cc1O)C#CCOc1cccc2ncccc12
Show InChI InChI=1S/C20H15N3O5/c24-16-10-13(11-22-19(16)20(27)23-12-18(25)26)4-3-9-28-17-7-1-6-15-14(17)5-2-8-21-15/h1-2,5-8,10-11,24H,9,12H2,(H,23,27)(H,25,26)
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n/an/a 772n/an/an/an/an/an/a



Jiangsu Hengrui Medicine Co., Ltd.

US Patent


Assay Description
The EGLN-1 (or EGLN-3) enzyme activity is determined using mass spectrometry (matrix-assisted laser desorption ionization, time-of-flight MS, MALD...


US Patent US10889546 (2021)

More data for this
Ligand-Target Pair
Prolyl hydroxylase EGLN3


(Homo sapiens (Human))
BDBM477217
PNG
(US10889546, Example 26)
Show SMILES CCNC(=O)CNC(=O)c1ncc(cc1O)C#Cc1ccc(NC(=O)C2CC2)cc1
Show InChI InChI=1S/C22H22N4O4/c1-2-23-19(28)13-25-22(30)20-18(27)11-15(12-24-20)4-3-14-5-9-17(10-6-14)26-21(29)16-7-8-16/h5-6,9-12,16,27H,2,7-8,13H2,1H3,(H,23,28)(H,25,30)(H,26,29)
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n/an/a 780n/an/an/an/an/an/a



Jiangsu Hengrui Medicine Co., Ltd.

US Patent


Assay Description
The EGLN-1 (or EGLN-3) enzyme activity is determined using mass spectrometry (matrix-assisted laser desorption ionization, time-of-flight MS, MALD...


US Patent US10889546 (2021)

More data for this
Ligand-Target Pair
Prolyl hydroxylase EGLN3


(Homo sapiens (Human))
BDBM477192
PNG
(US10889546, Example 2)
Show SMILES CC(C)C#Cc1cnc(C(=O)NCC(O)=O)c(O)c1
Show InChI InChI=1S/C13H14N2O4/c1-8(2)3-4-9-5-10(16)12(14-6-9)13(19)15-7-11(17)18/h5-6,8,16H,7H2,1-2H3,(H,15,19)(H,17,18)
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n/an/a 805n/an/an/an/an/an/a



Jiangsu Hengrui Medicine Co., Ltd.

US Patent


Assay Description
The EGLN-1 (or EGLN-3) enzyme activity is determined using mass spectrometry (matrix-assisted laser desorption ionization, time-of-flight MS, MALD...


US Patent US10889546 (2021)

More data for this
Ligand-Target Pair
Egl nine homolog 1


(Homo sapiens (Human))
BDBM477195
PNG
(US10889546, Example 5)
Show SMILES OC(=O)CNC(=O)c1ncc(cc1O)C#Cc1ccccc1
Show InChI InChI=1S/C16H12N2O4/c19-13-8-12(7-6-11-4-2-1-3-5-11)9-17-15(13)16(22)18-10-14(20)21/h1-5,8-9,19H,10H2,(H,18,22)(H,20,21)
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n/an/a 820n/an/an/an/an/an/a



Jiangsu Hengrui Medicine Co., Ltd.

US Patent


Assay Description
The EGLN-1 (or EGLN-3) enzyme activity is determined using mass spectrometry (matrix-assisted laser desorption ionization, time-of-flight MS, MALD...


US Patent US10889546 (2021)

More data for this
Ligand-Target Pair
Egl nine homolog 1


(Homo sapiens (Human))
BDBM477194
PNG
(US10889546, Example 4)
Show SMILES OC(=O)CNC(=O)c1ncc(cc1O)C#CC1CC1
Show InChI InChI=1S/C13H12N2O4/c16-10-5-9(4-3-8-1-2-8)6-14-12(10)13(19)15-7-11(17)18/h5-6,8,16H,1-2,7H2,(H,15,19)(H,17,18)
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n/an/a 835n/an/an/an/an/an/a



Jiangsu Hengrui Medicine Co., Ltd.

US Patent


Assay Description
The EGLN-1 (or EGLN-3) enzyme activity is determined using mass spectrometry (matrix-assisted laser desorption ionization, time-of-flight MS, MALD...


US Patent US10889546 (2021)

More data for this
Ligand-Target Pair
Egl nine homolog 1


(Homo sapiens (Human))
BDBM477213
PNG
(US10889546, Example 22)
Show SMILES CC(=O)Nc1ccc(cc1)C#Cc1cnc(C(=O)NCC(O)=O)c(O)c1
Show InChI InChI=1S/C18H15N3O5/c1-11(22)21-14-6-4-12(5-7-14)2-3-13-8-15(23)17(19-9-13)18(26)20-10-16(24)25/h4-9,23H,10H2,1H3,(H,20,26)(H,21,22)(H,24,25)
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n/an/a 950n/an/an/an/an/an/a



Jiangsu Hengrui Medicine Co., Ltd.

US Patent


Assay Description
The EGLN-1 (or EGLN-3) enzyme activity is determined using mass spectrometry (matrix-assisted laser desorption ionization, time-of-flight MS, MALD...


US Patent US10889546 (2021)

More data for this
Ligand-Target Pair
Egl nine homolog 1


(Homo sapiens (Human))
BDBM477199
PNG
(US10889546, Example 9)
Show SMILES CC(NC(=O)c1ncc(cc1O)C#Cc1ccc(cc1)C1CC1)C(O)=O
Show InChI InChI=1S/C20H18N2O4/c1-12(20(25)26)22-19(24)18-17(23)10-14(11-21-18)3-2-13-4-6-15(7-5-13)16-8-9-16/h4-7,10-12,16,23H,8-9H2,1H3,(H,22,24)(H,25,26)
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n/an/a 1.05E+3n/an/an/an/an/an/a



Jiangsu Hengrui Medicine Co., Ltd.

US Patent


Assay Description
The EGLN-1 (or EGLN-3) enzyme activity is determined using mass spectrometry (matrix-assisted laser desorption ionization, time-of-flight MS, MALD...


US Patent US10889546 (2021)

More data for this
Ligand-Target Pair
Egl nine homolog 1


(Homo sapiens (Human))
BDBM477214
PNG
(US10889546, Example 23)
Show SMILES CN(C)C(=O)c1ccc(cc1)C#Cc1cnc(C(=O)NCC(N)=O)c(O)c1
Show InChI InChI=1S/C19H18N4O4/c1-23(2)19(27)14-7-5-12(6-8-14)3-4-13-9-15(24)17(21-10-13)18(26)22-11-16(20)25/h5-10,24H,11H2,1-2H3,(H2,20,25)(H,22,26)
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n/an/a 1.06E+3n/an/an/an/an/an/a



Jiangsu Hengrui Medicine Co., Ltd.

US Patent


Assay Description
The EGLN-1 (or EGLN-3) enzyme activity is determined using mass spectrometry (matrix-assisted laser desorption ionization, time-of-flight MS, MALD...


US Patent US10889546 (2021)

More data for this
Ligand-Target Pair
Egl nine homolog 1


(Homo sapiens (Human))
BDBM477260
PNG
(US10889546, Example 68)
Show SMILES OC(=O)CNC(=O)c1ncc(cc1O)C#CCN(c1ccccc1)c1ccc(F)c(F)c1
Show InChI InChI=1S/C23H17F2N3O4/c24-18-9-8-17(12-19(18)25)28(16-6-2-1-3-7-16)10-4-5-15-11-20(29)22(26-13-15)23(32)27-14-21(30)31/h1-3,6-9,11-13,29H,10,14H2,(H,27,32)(H,30,31)
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n/an/a 1.20E+3n/an/an/an/an/an/a



Jiangsu Hengrui Medicine Co., Ltd.

US Patent


Assay Description
The EGLN-1 (or EGLN-3) enzyme activity is determined using mass spectrometry (matrix-assisted laser desorption ionization, time-of-flight MS, MALD...


US Patent US10889546 (2021)

More data for this
Ligand-Target Pair
Egl nine homolog 1


(Homo sapiens (Human))
BDBM477193
PNG
(US10889546, Example 3)
Show SMILES CC(C)(C)C#Cc1cnc(C(=O)NCC(O)=O)c(O)c1
Show InChI InChI=1S/C14H16N2O4/c1-14(2,3)5-4-9-6-10(17)12(15-7-9)13(20)16-8-11(18)19/h6-7,17H,8H2,1-3H3,(H,16,20)(H,18,19)
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n/an/a 1.22E+3n/an/an/an/an/an/a



Jiangsu Hengrui Medicine Co., Ltd.

US Patent


Assay Description
The EGLN-1 (or EGLN-3) enzyme activity is determined using mass spectrometry (matrix-assisted laser desorption ionization, time-of-flight MS, MALD...


US Patent US10889546 (2021)

More data for this
Ligand-Target Pair
Egl nine homolog 1


(Homo sapiens (Human))
BDBM107703
PNG
(US10889546, US2007/0299086 Table 2.4 | US8598210, ...)
Show SMILES OC(=O)CNC(=O)c1ncc(cc1O)-c1ccc(Cl)cc1
Show InChI InChI=1S/C14H11ClN2O4/c15-10-3-1-8(2-4-10)9-5-11(18)13(16-6-9)14(21)17-7-12(19)20/h1-6,18H,7H2,(H,17,21)(H,19,20)
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US Patent
n/an/a 1.39E+3n/an/an/an/an/an/a



Jiangsu Hengrui Medicine Co., Ltd.

US Patent


Assay Description
The EGLN-1 (or EGLN-3) enzyme activity is determined using mass spectrometry (matrix-assisted laser desorption ionization, time-of-flight MS, MALD...


US Patent US10889546 (2021)

More data for this
Ligand-Target Pair
Egl nine homolog 1


(Homo sapiens (Human))
BDBM477261
PNG
(US10889546, Example 69)
Show SMILES CCOc1cc(ccc1C)N(CC#Cc1cnc(C(=O)NCC(O)=O)c(O)c1)C(C)(C)C
Show InChI InChI=1S/C24H29N3O5/c1-6-32-20-13-18(10-9-16(20)2)27(24(3,4)5)11-7-8-17-12-19(28)22(25-14-17)23(31)26-15-21(29)30/h9-10,12-14,28H,6,11,15H2,1-5H3,(H,26,31)(H,29,30)
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n/an/a 1.41E+3n/an/an/an/an/an/a



Jiangsu Hengrui Medicine Co., Ltd.

US Patent


Assay Description
The EGLN-1 (or EGLN-3) enzyme activity is determined using mass spectrometry (matrix-assisted laser desorption ionization, time-of-flight MS, MALD...


US Patent US10889546 (2021)

More data for this
Ligand-Target Pair
Egl nine homolog 1


(Homo sapiens (Human))
BDBM477192
PNG
(US10889546, Example 2)
Show SMILES CC(C)C#Cc1cnc(C(=O)NCC(O)=O)c(O)c1
Show InChI InChI=1S/C13H14N2O4/c1-8(2)3-4-9-5-10(16)12(14-6-9)13(19)15-7-11(17)18/h5-6,8,16H,7H2,1-2H3,(H,15,19)(H,17,18)
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n/an/a 1.42E+3n/an/an/an/an/an/a



Jiangsu Hengrui Medicine Co., Ltd.

US Patent


Assay Description
The EGLN-1 (or EGLN-3) enzyme activity is determined using mass spectrometry (matrix-assisted laser desorption ionization, time-of-flight MS, MALD...


US Patent US10889546 (2021)

More data for this
Ligand-Target Pair
Egl nine homolog 1


(Homo sapiens (Human))
BDBM477265
PNG
(US10889546, US2007/0299086 Table 2.2 | US10889546,...)
Show SMILES CCc1ccc(cc1)-c1cnc(C(=O)NCC(O)=O)c(O)c1
Show InChI InChI=1S/C16H16N2O4/c1-2-10-3-5-11(6-4-10)12-7-13(19)15(17-8-12)16(22)18-9-14(20)21/h3-8,19H,2,9H2,1H3,(H,18,22)(H,20,21)
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n/an/a 1.50E+3n/an/an/an/an/an/a



Jiangsu Hengrui Medicine Co., Ltd.

US Patent


Assay Description
The EGLN-1 (or EGLN-3) enzyme activity is determined using mass spectrometry (matrix-assisted laser desorption ionization, time-of-flight MS, MALD...


US Patent US10889546 (2021)

More data for this
Ligand-Target Pair
Egl nine homolog 1


(Homo sapiens (Human))
BDBM477265
PNG
(US10889546, US2007/0299086 Table 2.2 | US10889546,...)
Show SMILES CCc1ccc(cc1)-c1cnc(C(=O)NCC(O)=O)c(O)c1
Show InChI InChI=1S/C16H16N2O4/c1-2-10-3-5-11(6-4-10)12-7-13(19)15(17-8-12)16(22)18-9-14(20)21/h3-8,19H,2,9H2,1H3,(H,18,22)(H,20,21)
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n/an/a 1.50E+3n/an/an/an/an/an/a



Jiangsu Hengrui Medicine Co., Ltd.

US Patent


Assay Description
The EGLN-1 (or EGLN-3) enzyme activity is determined using mass spectrometry (matrix-assisted laser desorption ionization, time-of-flight MS, MALD...


US Patent US10889546 (2021)

More data for this
Ligand-Target Pair
Egl nine homolog 1


(Homo sapiens (Human))
BDBM477218
PNG
(US10889546, Example 27)
Show SMILES CNC(=O)CNC(=O)c1ncc(cc1O)C#CCOc1ccccc1
Show InChI InChI=1S/C18H17N3O4/c1-19-16(23)12-21-18(24)17-15(22)10-13(11-20-17)6-5-9-25-14-7-3-2-4-8-14/h2-4,7-8,10-11,22H,9,12H2,1H3,(H,19,23)(H,21,24)
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n/an/a 1.70E+3n/an/an/an/an/an/a



Jiangsu Hengrui Medicine Co., Ltd.

US Patent


Assay Description
The EGLN-1 (or EGLN-3) enzyme activity is determined using mass spectrometry (matrix-assisted laser desorption ionization, time-of-flight MS, MALD...


US Patent US10889546 (2021)

More data for this
Ligand-Target Pair
Egl nine homolog 1


(Homo sapiens (Human))
BDBM477201
PNG
(US10889546, Example 11)
Show SMILES CC(C)(NC(=O)c1ncc(cc1O)C#Cc1ccc(F)cc1)C(O)=O
Show InChI InChI=1S/C18H15FN2O4/c1-18(2,17(24)25)21-16(23)15-14(22)9-12(10-20-15)4-3-11-5-7-13(19)8-6-11/h5-10,22H,1-2H3,(H,21,23)(H,24,25)
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n/an/a 1.94E+3n/an/an/an/an/an/a



Jiangsu Hengrui Medicine Co., Ltd.

US Patent


Assay Description
The EGLN-1 (or EGLN-3) enzyme activity is determined using mass spectrometry (matrix-assisted laser desorption ionization, time-of-flight MS, MALD...


US Patent US10889546 (2021)

More data for this
Ligand-Target Pair
Egl nine homolog 1


(Homo sapiens (Human))
BDBM477266
PNG
(US10889546, US2007/0299086 Table 2.3)
Show SMILES OC(=O)CNC(=O)c1ncc(cc1O)-c1ccccc1
Show InChI InChI=1S/C14H12N2O4/c17-11-6-10(9-4-2-1-3-5-9)7-15-13(11)14(20)16-8-12(18)19/h1-7,17H,8H2,(H,16,20)(H,18,19)
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n/an/a 2.03E+3n/an/an/an/an/an/a



Jiangsu Hengrui Medicine Co., Ltd.

US Patent


Assay Description
The EGLN-1 (or EGLN-3) enzyme activity is determined using mass spectrometry (matrix-assisted laser desorption ionization, time-of-flight MS, MALD...


US Patent US10889546 (2021)

More data for this
Ligand-Target Pair
Egl nine homolog 1


(Homo sapiens (Human))
BDBM477200
PNG
(US10889546, Example 10)
Show SMILES CCC(NC(=O)c1ncc(cc1O)C#Cc1ccc(F)cc1)C(O)=O
Show InChI InChI=1S/C18H15FN2O4/c1-2-14(18(24)25)21-17(23)16-15(22)9-12(10-20-16)4-3-11-5-7-13(19)8-6-11/h5-10,14,22H,2H2,1H3,(H,21,23)(H,24,25)
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n/an/a 2.03E+3n/an/an/an/an/an/a



Jiangsu Hengrui Medicine Co., Ltd.

US Patent


Assay Description
The EGLN-1 (or EGLN-3) enzyme activity is determined using mass spectrometry (matrix-assisted laser desorption ionization, time-of-flight MS, MALD...


US Patent US10889546 (2021)

More data for this
Ligand-Target Pair
Egl nine homolog 1


(Homo sapiens (Human))
BDBM477217
PNG
(US10889546, Example 26)
Show SMILES CCNC(=O)CNC(=O)c1ncc(cc1O)C#Cc1ccc(NC(=O)C2CC2)cc1
Show InChI InChI=1S/C22H22N4O4/c1-2-23-19(28)13-25-22(30)20-18(27)11-15(12-24-20)4-3-14-5-9-17(10-6-14)26-21(29)16-7-8-16/h5-6,9-12,16,27H,2,7-8,13H2,1H3,(H,23,28)(H,25,30)(H,26,29)
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n/an/a 2.13E+3n/an/an/an/an/an/a



Jiangsu Hengrui Medicine Co., Ltd.

US Patent


Assay Description
The EGLN-1 (or EGLN-3) enzyme activity is determined using mass spectrometry (matrix-assisted laser desorption ionization, time-of-flight MS, MALD...


US Patent US10889546 (2021)

More data for this
Ligand-Target Pair
Egl nine homolog 1


(Homo sapiens (Human))
BDBM477264
PNG
(US10889546, US2007/0299086 Table 2.1)
Show SMILES Cc1cccc(c1)-c1cnc(C(=O)NCC(O)=O)c(O)c1
Show InChI InChI=1S/C15H14N2O4/c1-9-3-2-4-10(5-9)11-6-12(18)14(16-7-11)15(21)17-8-13(19)20/h2-7,18H,8H2,1H3,(H,17,21)(H,19,20)
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n/an/a 2.22E+3n/an/an/an/an/an/a



Jiangsu Hengrui Medicine Co., Ltd.

US Patent


Assay Description
The EGLN-1 (or EGLN-3) enzyme activity is determined using mass spectrometry (matrix-assisted laser desorption ionization, time-of-flight MS, MALD...


US Patent US10889546 (2021)

More data for this
Ligand-Target Pair
Egl nine homolog 1


(Homo sapiens (Human))
BDBM477204
PNG
(US10889546, Example 13)
Show SMILES CN(CC(O)=O)C(=O)c1nc(Br)c(cc1O)C#Cc1ccc(C)cc1
Show InChI InChI=1S/C18H15BrN2O4/c1-11-3-5-12(6-4-11)7-8-13-9-14(22)16(20-17(13)19)18(25)21(2)10-15(23)24/h3-6,9,22H,10H2,1-2H3,(H,23,24)
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n/an/a 2.65E+3n/an/an/an/an/an/a



Jiangsu Hengrui Medicine Co., Ltd.

US Patent


Assay Description
The EGLN-1 (or EGLN-3) enzyme activity is determined using mass spectrometry (matrix-assisted laser desorption ionization, time-of-flight MS, MALD...


US Patent US10889546 (2021)

More data for this
Ligand-Target Pair
Egl nine homolog 1


(Homo sapiens (Human))
BDBM477203
PNG
(US10889546, Example 12)
Show SMILES CCc1ccc(cc1)C#Cc1cnc(C(=O)CCC(O)=O)c(O)c1
Show InChI InChI=1S/C19H17NO4/c1-2-13-3-5-14(6-4-13)7-8-15-11-17(22)19(20-12-15)16(21)9-10-18(23)24/h3-6,11-12,22H,2,9-10H2,1H3,(H,23,24)
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n/an/a 2.78E+3n/an/an/an/an/an/a



Jiangsu Hengrui Medicine Co., Ltd.

US Patent


Assay Description
The EGLN-1 (or EGLN-3) enzyme activity is determined using mass spectrometry (matrix-assisted laser desorption ionization, time-of-flight MS, MALD...


US Patent US10889546 (2021)

More data for this
Ligand-Target Pair
Egl nine homolog 1


(Homo sapiens (Human))
BDBM477220
PNG
(US10889546, Example 29)
Show SMILES CCc1ccc(OCC#Cc2cnc(C(=O)NCC(=O)OC)c(O)c2)cc1
Show InChI InChI=1S/C20H20N2O5/c1-3-14-6-8-16(9-7-14)27-10-4-5-15-11-17(23)19(21-12-15)20(25)22-13-18(24)26-2/h6-9,11-12,23H,3,10,13H2,1-2H3,(H,22,25)
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n/an/a 3.12E+3n/an/an/an/an/an/a



Jiangsu Hengrui Medicine Co., Ltd.

US Patent


Assay Description
The EGLN-1 (or EGLN-3) enzyme activity is determined using mass spectrometry (matrix-assisted laser desorption ionization, time-of-flight MS, MALD...


US Patent US10889546 (2021)

More data for this
Ligand-Target Pair
Egl nine homolog 1


(Homo sapiens (Human))
BDBM477221
PNG
(US10889546, Example 30)
Show SMILES CC(C)OC(=O)CNC(=O)c1ncc(cc1O)C#CCOc1ccc(cc1)C#N
Show InChI InChI=1S/C21H19N3O5/c1-14(2)29-19(26)13-24-21(27)20-18(25)10-16(12-23-20)4-3-9-28-17-7-5-15(11-22)6-8-17/h5-8,10,12,14,25H,9,13H2,1-2H3,(H,24,27)
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n/an/a 3.76E+3n/an/an/an/an/an/a



Jiangsu Hengrui Medicine Co., Ltd.

US Patent


Assay Description
The EGLN-1 (or EGLN-3) enzyme activity is determined using mass spectrometry (matrix-assisted laser desorption ionization, time-of-flight MS, MALD...


US Patent US10889546 (2021)

More data for this
Ligand-Target Pair
Egl nine homolog 1


(Homo sapiens (Human))
BDBM477191
PNG
(US10889546, Example 1)
Show SMILES CC#Cc1cnc(C(=O)NCC(O)=O)c(O)c1
Show InChI InChI=1S/C11H10N2O4/c1-2-3-7-4-8(14)10(12-5-7)11(17)13-6-9(15)16/h4-5,14H,6H2,1H3,(H,13,17)(H,15,16)
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n/an/a 4.53E+3n/an/an/an/an/an/a



Jiangsu Hengrui Medicine Co., Ltd.

US Patent


Assay Description
The EGLN-1 (or EGLN-3) enzyme activity is determined using mass spectrometry (matrix-assisted laser desorption ionization, time-of-flight MS, MALD...


US Patent US10889546 (2021)

More data for this
Ligand-Target Pair
Egl nine homolog 1


(Homo sapiens (Human))
BDBM477215
PNG
(US10889546, Example 24)
Show SMILES CCCCC(=O)Nc1ccc(cc1)C#Cc1cnc(C(=O)NCC(=O)OCC2CC2)c(O)c1
Show InChI InChI=1S/C25H27N3O5/c1-2-3-4-22(30)28-20-11-9-17(10-12-20)5-8-19-13-21(29)24(26-14-19)25(32)27-15-23(31)33-16-18-6-7-18/h9-14,18,29H,2-4,6-7,15-16H2,1H3,(H,27,32)(H,28,30)
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n/an/a 5.20E+3n/an/an/an/an/an/a



Jiangsu Hengrui Medicine Co., Ltd.

US Patent


Assay Description
The EGLN-1 (or EGLN-3) enzyme activity is determined using mass spectrometry (matrix-assisted laser desorption ionization, time-of-flight MS, MALD...


US Patent US10889546 (2021)

More data for this
Ligand-Target Pair
Egl nine homolog 1


(Homo sapiens (Human))
BDBM477196
PNG
(US10889546, Example 6)
Show SMILES COC(=O)CNC(=O)c1ncc(cc1O)C#Cc1ccccc1
Show InChI InChI=1S/C17H14N2O4/c1-23-15(21)11-19-17(22)16-14(20)9-13(10-18-16)8-7-12-5-3-2-4-6-12/h2-6,9-10,20H,11H2,1H3,(H,19,22)
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n/an/a 5.50E+3n/an/an/an/an/an/a



Jiangsu Hengrui Medicine Co., Ltd.

US Patent


Assay Description
The EGLN-1 (or EGLN-3) enzyme activity is determined using mass spectrometry (matrix-assisted laser desorption ionization, time-of-flight MS, MALD...


US Patent US10889546 (2021)

More data for this
Ligand-Target Pair
Egl nine homolog 1


(Homo sapiens (Human))
BDBM477223
PNG
(US10889546, Example 32)
Show SMILES CN(C)C(=O)CNC(=O)c1ncc(cc1O)C#CCOc1ccc(Cl)cc1
Show InChI InChI=1S/C19H18ClN3O4/c1-23(2)17(25)12-22-19(26)18-16(24)10-13(11-21-18)4-3-9-27-15-7-5-14(20)6-8-15/h5-8,10-11,24H,9,12H2,1-2H3,(H,22,26)
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n/an/a 6.10E+3n/an/an/an/an/an/a



Jiangsu Hengrui Medicine Co., Ltd.

US Patent


Assay Description
The EGLN-1 (or EGLN-3) enzyme activity is determined using mass spectrometry (matrix-assisted laser desorption ionization, time-of-flight MS, MALD...


US Patent US10889546 (2021)

More data for this
Ligand-Target Pair
Egl nine homolog 1


(Homo sapiens (Human))
BDBM477222
PNG
(US10889546, Example 31)
Show SMILES Oc1cc(cnc1C(=O)NCC(=O)OC1CC1)C#CCOc1ccc(F)cc1
Show InChI InChI=1S/C20H17FN2O5/c21-14-3-5-15(6-4-14)27-9-1-2-13-10-17(24)19(22-11-13)20(26)23-12-18(25)28-16-7-8-16/h3-6,10-11,16,24H,7-9,12H2,(H,23,26)
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n/an/a 6.12E+3n/an/an/an/an/an/a



Jiangsu Hengrui Medicine Co., Ltd.

US Patent


Assay Description
The EGLN-1 (or EGLN-3) enzyme activity is determined using mass spectrometry (matrix-assisted laser desorption ionization, time-of-flight MS, MALD...


US Patent US10889546 (2021)

More data for this
Ligand-Target Pair
Egl nine homolog 1


(Homo sapiens (Human))
BDBM477216
PNG
(US10889546, Example 25)
Show SMILES CCCCNC(=O)c1ccc(cc1)C#Cc1cnc(C(=O)NCC(=O)OC(C)C)c(O)c1
Show InChI InChI=1S/C24H27N3O5/c1-4-5-12-25-23(30)19-10-8-17(9-11-19)6-7-18-13-20(28)22(26-14-18)24(31)27-15-21(29)32-16(2)3/h8-11,13-14,16,28H,4-5,12,15H2,1-3H3,(H,25,30)(H,27,31)
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n/an/a 6.21E+3n/an/an/an/an/an/a



Jiangsu Hengrui Medicine Co., Ltd.

US Patent


Assay Description
The EGLN-1 (or EGLN-3) enzyme activity is determined using mass spectrometry (matrix-assisted laser desorption ionization, time-of-flight MS, MALD...


US Patent US10889546 (2021)

More data for this
Ligand-Target Pair
Egl nine homolog 1


(Homo sapiens (Human))
BDBM477209
PNG
(US10889546, Example 18)
Show SMILES OC(=O)CNC(=O)c1ncc(cc1O)C#Cc1ccc(cc1)-c1ccccc1
Show InChI InChI=1S/C22H16N2O4/c25-19-12-16(13-23-21(19)22(28)24-14-20(26)27)7-6-15-8-10-18(11-9-15)17-4-2-1-3-5-17/h1-5,8-13,25H,14H2,(H,24,28)(H,26,27)
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US Patent
n/an/a 8.13E+3n/an/an/an/an/an/a



Jiangsu Hengrui Medicine Co., Ltd.

US Patent


Assay Description
The EGLN-1 (or EGLN-3) enzyme activity is determined using mass spectrometry (matrix-assisted laser desorption ionization, time-of-flight MS, MALD...


US Patent US10889546 (2021)

More data for this
Ligand-Target Pair
* indicates data uncertainty>20%